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George Kirov, … , Michael C. O’Donovan, Michael J. Owen
Published June 1, 2005
Citation Information: J Clin Invest. 2005;115(6):1440-1448. https://doi.org/10.1172/JCI24759.
Citation Information: J Clin Invest. 2005;115(6):1440-1448. https://doi.org/10.1172/JCI24759.
Abstract
Genetic epidemiological studies suggest that individual variation in susceptibility to schizophrenia is largely genetic, reflecting alleles of moderate to small effect in multiple genes. Molecular genetic studies have identified a number of potential regions of linkage and 2 associated chromosomal abnormalities, and accumulating evidence favors several positional candidate genes. These findings are grounds for optimism that insight into genetic factors associated with schizophrenia will help further our understanding of this disease and contribute to the development of new ways to treat it.
Authors
George Kirov, Michael C. O’Donovan, Michael J. Owen
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Citation information
Citations to this article in year 2010 (2)
| Title and authors | Publication | Year |
|---|---|---|
|
Dysregulation of presynaptic calcium and synaptic plasticity in a mouse model of 22q11 deletion syndrome.
Earls LR, Bayazitov IT, Fricke RG, Berry RB, Illingworth E, Mittleman G, Zakharenko SS |
The Journal of neuroscience : the official journal of the Society for Neuroscience | 2010 |
|
[Cognitive disorders in schizophrenic patients].
Volz HP, Reischies F, Riedel M |
Der Nervenarzt | 2010 |
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