Gut microbial metabolite connections to cardiovascular disease call for gutsy therapeutic approaches

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Frank Ruschitzka, Antonio Vidal-Puig, Seyed Soheil Saeedi Saravi

The 2025 Nobel Prize in Physiology or Medicine — a bridge to peripheral immune tolerance

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Jeffrey A. Bluestone

Genetic and environmental influences in autism: guiding the future of tailored early detection and intervention

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Alexandra L. Bey, Scott Soderling, Geraldine Dawson

Ruling in, ruling out: the clinical utility of plasma biomarkers in diagnosis of Alzheimer’s disease

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Julie K. Wisch, Beau M. Ances

The pathogenesis of hepatic steatosis in MASLD: a lipid droplet perspective

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Natalie Krahmer, Tobias C. Walther, Robert V. Farese Jr.

Welsh, González, and Negulescu share Lasker Award recognizing transformative treatments for people with cystic fibrosis

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Benjamin D. Singer, G.R. Scott Budinger

Microbiota in interstitial cystitis/bladder pain syndrome: evidence and opportunities

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David J. Klumpp

An unexpected role for the brain in the pathogenesis of diabetic ketoacidosis

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Zaman Mirzadeh, Gregory J. Morton, Irl B. Hirsch, Michael W. Schwartz

Vaccines in cancer treatment and prevention: the time is now

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William Becker, W. Kimryn Rathmell

Fat, fibrosis, and the future: navigating the maze of MASLD/MASH

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Scott L. Friedman