This investigation was undertaken in order to (a) characterize the postprandial inflow of individual bile acids to the liver and (b) determine if peripheral venous bile acid levels always adequately reflect the portal venous concentration, or if saturation of hepatic bile acid uptake can occur under physiological conditions. In five patients with uncomplicated cholesterol gallstone disease, the umbilical cord was cannulated during cholecystectomy, and a catheter was left in the left portal branch for 5 to 7 d. The serum concentrations of cholic acid, chenodeoxycholic acid, and deoxycholic acid in portal venous and systemic circulation were then determined at intervals of 15 to 30 min before and after a standardized meal. A highly accurate and specific gas chromatographic/mass spectrometric technique was used.
Bo Angelin, Ingemar Björkhem, Kurt Einarsson, Staffan Ewerth
Year: | 2025 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 | 2014 | 2013 | 2012 | 2011 | 2010 | 2009 | 2008 | 2007 | 2006 | 2005 | 2004 | 2003 | 2002 | 2000 | 1999 | 1998 | 1997 | 1996 | 1995 | 1994 | 1993 | 1992 | 1991 | 1990 | 1989 | 1988 | 1987 | 1986 | 1985 | 1984 | 1983 | 1978 | Total |
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Citations: | 1 | 5 | 3 | 9 | 12 | 7 | 10 | 5 | 5 | 4 | 9 | 11 | 2 | 1 | 1 | 4 | 3 | 1 | 5 | 2 | 2 | 1 | 3 | 1 | 1 | 2 | 1 | 3 | 3 | 2 | 5 | 3 | 4 | 2 | 5 | 5 | 8 | 5 | 11 | 4 | 3 | 1 | 175 |
Title and authors | Publication | Year |
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Minocycline-induced disruption of the intestinal FXR-FGF15 axis impairs osteogenesis in mice
Matthew Carson, Amy Warner, Jessica Hathaway-Schrader, Vincenza Geiser, Joseph Kim, Joy Gerasco, William Hill, John Lemasters, Alexander Alekseyenko, Yongren Wu, Hai Yao, Jose Aguirre, Caroline Westwater, Chad Novince |
JCI Insight | 2023 |
Sex, puberty, and the gut microbiome.
Sisk-Hackworth L, Kelley ST, Thackray VG |
Reproduction (Cambridge, England) | 2023 |
Hepatocyte apical bulkheads provide a mechanical means to oppose bile pressure
Bebelman MP, Bovyn MJ, Mayer CM, Delpierre J, Naumann R, Martins NP, Honigmann A, Kalaidzidis Y, Haas PA, Zerial M |
The Journal of Cell Biology | 2023 |
Bile acid signaling in the regulation of whole body metabolic and immunological homeostasis.
Jia W, Li Y, Cheung KCP, Zheng X |
Science China Life Sciences | 2023 |
Bile acid signalling and its role in anxiety disorders.
Chen S, Shao Q, Chen J, Lv X, Ji J, Liu Y, Song Y |
Frontiers in Endocrinology | 2023 |