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Bo Angelin, … , Kurt Einarsson, Staffan Ewerth
Published October 1, 1982
Citation Information: J Clin Invest. 1982;70(4):724-731. https://doi.org/10.1172/JCI110668.
Citation Information: J Clin Invest. 1982;70(4):724-731. https://doi.org/10.1172/JCI110668.
Abstract
This investigation was undertaken in order to (a) characterize the postprandial inflow of individual bile acids to the liver and (b) determine if peripheral venous bile acid levels always adequately reflect the portal venous concentration, or if saturation of hepatic bile acid uptake can occur under physiological conditions. In five patients with uncomplicated cholesterol gallstone disease, the umbilical cord was cannulated during cholecystectomy, and a catheter was left in the left portal branch for 5 to 7 d. The serum concentrations of cholic acid, chenodeoxycholic acid, and deoxycholic acid in portal venous and systemic circulation were then determined at intervals of 15 to 30 min before and after a standardized meal. A highly accurate and specific gas chromatographic/mass spectrometric technique was used.
Authors
Bo Angelin, Ingemar Björkhem, Kurt Einarsson, Staffan Ewerth
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Citation information
Citations to this article in year 2020 (12)
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Journal of Clinical Investigation | 2020 |
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Distinct Postprandial Bile Acids Responses to a High-Calorie Diet in Men Volunteers Underscore Metabolically Healthy and Unhealthy Phenotypes
A Lamaziere, D Rainteau, P KC, L Humbert, E Gauliard, F Ichou, M Ponnaiah, N Bouby, JE Salem, JM Mallet, M Guerin, P Lesnik |
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Hepatic Bile Acid Reuptake in the Rat Depends on Bile Acid Conjugation but Not on Agonistic Properties towards FXR and TGR5
SA Trammell, JS Svenningsen, JJ Holst, MP Gillum, RE Kuhre |
Molecules (Basel, Switzerland) | 2020 |
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Bilio-enteric flow and plasma concentrations of bile acids after gastric bypass and sleeve gastrectomy
A Eiken, S Fuglsang, M Eiken, MS Svane, RE Kuhre, NJ Albrechtsen, SH Hansen, SA Trammell, JS Svenningsen, JF Rehfeld, KN Bojsen-Møller, NB Jørgensen, JJ Holst, S Madsbad, JL Madsen, C Dirksen |
International Journal of Obesity | 2020 |
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Modulation of immune responses by bile acid receptor agonists in myasthenia gravis
Q Howlett-Prieto, C Langer, K Rezania, B Soliven |
Journal of Neuroimmunology | 2020 |
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A Physiology-Based Model of Bile Acid Distribution and Metabolism Under Healthy and Pathologic Conditions in Human Beings
V Voronova, V Sokolov, A Al-Khaifi, S Straniero, C Kumar, K Peskov, G Helmlinger, M Rudling, B Angelin |
CMGH Cellular and Molecular Gastroenterology and Hepatology | 2020 |
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Unraveling Host-Gut Microbiota Dialogue and Its Impact on Cholesterol Levels
R Villette, P KC, S Beliard, MF Tapia, D Rainteau, M Guerin, P Lesnik |
Frontiers in pharmacology | 2020 |
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Biliary excretion of gadobenate dimeglumine causing degradation of magnetic resonance cholangiopancreatography (MRCP)
LM Trunz, FF Guglielmo, SK Selvarajan, HV Naringrekar, A Alturki, JK Dave, DG Mitchell |
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Regulation of bile acid metabolism in biliary atresia: reduction of FGF19 by Kasai portoenterostomy and possible relation to early outcome
H Johansson, JF Svensson, M Almström, NV Hul, M Rudling, B Angelin, G Nowak, B Fischler, E Ellis |
Journal of Internal Medicine | 2020 |
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Fasting serum total bile acid level is associated with coronary artery disease, myocardial infarction and severity of coronary lesions
W Li, S Shu, L Cheng, X Hao, L Wang, Y Wu, Z Yuan, J Zhou |
Atherosclerosis | 2020 |
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Bile Acids: A Communication Channel in the Gut-Brain Axis
VF Monteiro-Cardoso, M Corlianò, RR Singaraja |
NeuroMolecular Medicine | 2020 |
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Mammalian Sterols: Novel Biological Roles of Cholesterol Synthesis Intermediates, Oxysterols and Bile Acids
D Rozman, R Gebhardt |
2020 |
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