Citations to this article
Citation Information: J Clin Invest. 1982;70(4):724-731. https://doi.org/10.1172/JCI110668.
Abstract
This investigation was undertaken in order to (a) characterize the postprandial inflow of individual bile acids to the liver and (b) determine if peripheral venous bile acid levels always adequately reflect the portal venous concentration, or if saturation of hepatic bile acid uptake can occur under physiological conditions. In five patients with uncomplicated cholesterol gallstone disease, the umbilical cord was cannulated during cholecystectomy, and a catheter was left in the left portal branch for 5 to 7 d. The serum concentrations of cholic acid, chenodeoxycholic acid, and deoxycholic acid in portal venous and systemic circulation were then determined at intervals of 15 to 30 min before and after a standardized meal. A highly accurate and specific gas chromatographic/mass spectrometric technique was used.
Authors
Bo Angelin, Ingemar Björkhem, Kurt Einarsson, Staffan Ewerth
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Citations to this article in year 2009 (4)
| Title and authors | Publication | Year |
|---|---|---|
|
TGR5-mediated bile acid sensing controls glucose homeostasis
C Thomas, A Gioiello, L Noriega, A Strehle, J Oury, G Rizzo, A Macchiarulo, H Yamamoto, C Mataki, M Pruzanski, R Pellicciari, J Auwerx, K Schoonjans |
Cell Metabolism | 2009 |
|
Serum Bile Acids Are Higher in Humans With Prior Gastric Bypass: Potential Contribution to Improved Glucose and Lipid Metabolism
ME Patti, SM Houten, AC Bianco, R Bernier, PR Larsen, JJ Holst, MK Badman, E Maratos-Flier, EC Mun, J Pihlajamaki, J Auwerx, AB Goldfine |
Obesity | 2009 |
|
Circadian dysregulation disrupts bile acid homeostasis
K Ma, R Xiao, HT Tseng, L Shan, L Fu, DD Moore |
PloS one | 2009 |
|
Efficacy of urine bile acid as a non-invasive indicator of liver damage in rats
H Kawai, N Kudo, Y Kawashima, A Mitsumoto |
The Journal of Toxicological Sciences | 2009 |
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