Citations to this article
Citation Information: J Clin Invest. 1982;70(4):724-731. https://doi.org/10.1172/JCI110668.
Abstract
This investigation was undertaken in order to (a) characterize the postprandial inflow of individual bile acids to the liver and (b) determine if peripheral venous bile acid levels always adequately reflect the portal venous concentration, or if saturation of hepatic bile acid uptake can occur under physiological conditions. In five patients with uncomplicated cholesterol gallstone disease, the umbilical cord was cannulated during cholecystectomy, and a catheter was left in the left portal branch for 5 to 7 d. The serum concentrations of cholic acid, chenodeoxycholic acid, and deoxycholic acid in portal venous and systemic circulation were then determined at intervals of 15 to 30 min before and after a standardized meal. A highly accurate and specific gas chromatographic/mass spectrometric technique was used.
Authors
Bo Angelin, Ingemar Björkhem, Kurt Einarsson, Staffan Ewerth
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Citations to this article in year 2017 (5)
| Title and authors | Publication | Year |
|---|---|---|
|
Bile Acid Uptake Transporters as Targets for Therapy
D Slijepcevic, SF van de Graaf |
Digestive Diseases | 2017 |
|
Determinants of postprandial plasma bile acid kinetics in human volunteers
J Fiamoncini, AM Yiorkas, K Gedrich, M Rundle, SI Alsters, G Roeselers, TJ van Broek, T Clavel, I Lagkouvardos, S Wopereis, G Frost, B Ommen, AI Blakemore, H Daniel |
AJP Gastrointestinal and Liver Physiology | 2017 |
|
Bariatric Surgery: A Perspective for Primary Care
S Kizy, C Jahansouz, K Wirth, S Ikramuddin, D Leslie |
Diabetes spectrum : a publication of the American Diabetes Association | 2017 |
|
Transhepatic bile acid kinetics in pigs and humans
HM Eggink, FS van Nierop, MG Schooneman, A Boelen, A Kalsbeek, M Koehorst, GA Have, LM de Brauw, AK Groen, JA Romijn, NE Deutz, MR Soeters |
Clinical nutrition (Edinburgh, Scotland) | 2017 |
|
Complex interaction between circadian rhythm and diet on bile acid homeostasis in male rats
HM Eggink, JE Oosterman, P Goede, EM de Vries, E Foppen, M Koehorst, AK Groen, A Boelen, JA Romijn, SE la Fleur, MR Soeters, A Kalsbeek |
Chronobiology International | 2017 |
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