Citations to this article
Citation Information: J Clin Invest. 1982;70(4):724-731. https://doi.org/10.1172/JCI110668.
Abstract
This investigation was undertaken in order to (a) characterize the postprandial inflow of individual bile acids to the liver and (b) determine if peripheral venous bile acid levels always adequately reflect the portal venous concentration, or if saturation of hepatic bile acid uptake can occur under physiological conditions. In five patients with uncomplicated cholesterol gallstone disease, the umbilical cord was cannulated during cholecystectomy, and a catheter was left in the left portal branch for 5 to 7 d. The serum concentrations of cholic acid, chenodeoxycholic acid, and deoxycholic acid in portal venous and systemic circulation were then determined at intervals of 15 to 30 min before and after a standardized meal. A highly accurate and specific gas chromatographic/mass spectrometric technique was used.
Authors
Bo Angelin, Ingemar Björkhem, Kurt Einarsson, Staffan Ewerth
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Citations to this article in year 2006 (5)
| Title and authors | Publication | Year |
|---|---|---|
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Integrated Upper Gastrointestinal Response to Food Intake
M Camilleri |
Gastroenterology | 2006 |
|
Circulating intestinal fibroblast growth factor 19 has a pronounced diurnal variation and modulates hepatic bile acid synthesis in man
T Lundåsen, C Gälman, B Angelin, M Rudling |
Journal of Internal Medicine | 2006 |
|
PKCζ Is Required for Microtubule-Based Motility of Vesicles Containing the ntcp Transporter
S Sarkar, E Bananis, S Nath, MS Anwer, AW Wolkoff, JW Murray |
Traffic | 2006 |
|
Biphasic regulation by bile acids of dermal fibroblast proliferation through regulation of cAMP production and COX-2 expression level
JP Meng, S Ceryak, Z Aratsu, L Jones, L Epstein, B Bouscarel |
American journal of physiology. Cell physiology | 2006 |
|
Bile acids stimulate PKCα autophosphorylation and activation: role in the attenuation of prostaglandin E 1 -induced cAMP production in human dermal fibroblasts
M Le, L Krilov, J Meng, K Chapin-Kennedy, S Ceryak, B Bouscarel |
AJP Gastrointestinal and Liver Physiology | 2006 |
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