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Newton E. Morton
Published June 1, 2005
Citation Information: J Clin Invest. 2005;115(6):1425-1430. https://doi.org/10.1172/JCI25032.
Citation Information: J Clin Invest. 2005;115(6):1425-1430. https://doi.org/10.1172/JCI25032.
Abstract
The causal chain between a gene and its effect on disease susceptibility cannot be understood until the effect has been localized in the DNA sequence. Recently, polymorphisms incorporated in the HapMap Project have made linkage disequilibrium (LD) the most powerful tool for localization. The genetics of LD, the maps and databases that it provides, and their use for association mapping, as well as alternative methods for gene localization, are briefly described.
Authors
Newton E. Morton
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Citations to this article in year 2009 (2)
| Title and authors | Publication | Year |
|---|---|---|
|
Bioinformatics for Systems Biology
S Krawetz |
2009 | |
|
Analytical Approaches and Population Types for Finding and Utilizing QTL in Complex Plant Populations
CH Sneller, DE Mather, S Crepieux |
Crop Science | 2009 |
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