Go to JCI Insight
  • About
  • Editors
  • Consulting Editors
  • For authors
  • Publication ethics
  • Publication alerts by email
  • Advertising
  • Job board
  • Contact
  • Clinical Research and Public Health
  • Current issue
  • Past issues
  • By specialty
    • COVID-19
    • Cardiology
    • Gastroenterology
    • Immunology
    • Metabolism
    • Nephrology
    • Neuroscience
    • Oncology
    • Pulmonology
    • Vascular biology
    • All ...
  • Videos
    • Conversations with Giants in Medicine
    • Video Abstracts
  • Reviews
    • View all reviews ...
    • Complement Biology and Therapeutics (May 2025)
    • Evolving insights into MASLD and MASH pathogenesis and treatment (Apr 2025)
    • Microbiome in Health and Disease (Feb 2025)
    • Substance Use Disorders (Oct 2024)
    • Clonal Hematopoiesis (Oct 2024)
    • Sex Differences in Medicine (Sep 2024)
    • Vascular Malformations (Apr 2024)
    • View all review series ...
  • Viewpoint
  • Collections
    • In-Press Preview
    • Clinical Research and Public Health
    • Research Letters
    • Letters to the Editor
    • Editorials
    • Commentaries
    • Editor's notes
    • Reviews
    • Viewpoints
    • 100th anniversary
    • Top read articles

  • Current issue
  • Past issues
  • Specialties
  • Reviews
  • Review series
  • Conversations with Giants in Medicine
  • Video Abstracts
  • In-Press Preview
  • Clinical Research and Public Health
  • Research Letters
  • Letters to the Editor
  • Editorials
  • Commentaries
  • Editor's notes
  • Reviews
  • Viewpoints
  • 100th anniversary
  • Top read articles
  • About
  • Editors
  • Consulting Editors
  • For authors
  • Publication ethics
  • Publication alerts by email
  • Advertising
  • Job board
  • Contact

Citations to this article

Linkage disequilibrium maps and association mapping
Newton E. Morton
Newton E. Morton
Published June 1, 2005
Citation Information: J Clin Invest. 2005;115(6):1425-1430. https://doi.org/10.1172/JCI25032.
View: Text | PDF
Review Series Article has an altmetric score of 1

Linkage disequilibrium maps and association mapping

  • Text
  • PDF
Abstract

The causal chain between a gene and its effect on disease susceptibility cannot be understood until the effect has been localized in the DNA sequence. Recently, polymorphisms incorporated in the HapMap Project have made linkage disequilibrium (LD) the most powerful tool for localization. The genetics of LD, the maps and databases that it provides, and their use for association mapping, as well as alternative methods for gene localization, are briefly described.

Authors

Newton E. Morton

×

Total citations by year

Year: 2022 2021 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 2006 2005 Total
Citations: 1 2 3 1 2 1 1 2 1 1 2 5 9 3 1 35
Citation information
This citation data is accumulated from CrossRef, which receives citation information from participating publishers, including this journal. Not all publishers participate in CrossRef, so this information is not comprehensive. Additionally, data may not reflect the most current citations to this article, and the data may differ from citation information available from other sources (for example, Google Scholar, Web of Science, and Scopus).

Citations to this article in year 2007 (9)

Title and authors Publication Year
Genotype matrix mapping: searching for quantitative trait loci interactions in genetic variation in complex traits
S Isobe, A Nakaya, S Tabata
DNA research : an international journal for rapid publication of reports on genes and genomes 2007
Magnetic resonance imaging as a tool for in vivo and ex vivo anatomical phenotyping in experimental genetic models
A Pitiot, Z Pausova, M Prior, J Perrin, N Loyse, T Paus
Human Brain Mapping 2007
Association Between Human Polymorphic DNA Markers and Hypoxia Adaptation in Sherpa Detected by a Preliminary Genome Scan
S Malacrida, Y Katsuyama, Y Droma, B Basnyat, C Angelini, M Ota, GA Danieli
Annals of Human Genetics 2007
Genetic Variability of Major Inflammatory Mediators Has No Impact on the Outcome of Kidney Transplantation
I Brabcova, J Petrasek, P Hribova, K Hyklova, K Bartosova, J Lacha, O Viklický
Transplantation 2007
A novel method to express SNP-based genetic heterogeneity,Ψ, and its use to measure linkage disequilibrium for multiple SNPs,Dg, and to estimate absolute maximum of haplotype frequency
R Yamada, F Matsuda
Genetic Epidemiology 2007
Diagnosis of neuronal ceroid lipofuscinosis: mutation detection strategies
AL Getty, PG Rothberg, DA Pearce
Expert Opinion on Medical Diagnostics 2007
snp.plotter: an R-based SNP/haplotype association and linkage disequilibrium plotting package
A Luna, KK Nicodemus
Bioinformatics 2007
Mechanisms of disease: genetics of rheumatoid arthritis--ethnic differences in disease-associated genes
R Yamada, K Yamamoto
Nature Clinical Practice Rheumatology 2007
Magnetic resonance imaging as a tool for in vivo and ex vivo anatomical phenotyping in experimental genetic models.
Pitiot A, Pausova Z, Prior M, Perrin J, Loyse N, Paus T
Human Brain Mapping 2007

Advertisement

Copyright © 2025 American Society for Clinical Investigation
ISSN: 0021-9738 (print), 1558-8238 (online)

Sign up for email alerts

On 1 Facebook pages
79 readers on Mendeley
2 readers on CiteULike
See more details