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Jane E.B. Reusch
Published October 1, 2003
Citation Information: J Clin Invest. 2003;112(7):986-988. https://doi.org/10.1172/JCI19902.
Citation Information: J Clin Invest. 2003;112(7):986-988. https://doi.org/10.1172/JCI19902.
Abstract
Glycemic control is the primary mediator of diabetic microvascular complications and also contributes to macrovascular complications. A new study (see related article beginning on page 1049) reveals a previously unrecognized association between oxidant activation of poly(ADP ribose) polymerase (PARP) and upregulation of known mediators of glycemic injury. Inhibitors of PARP may have potential therapeutic roles in the prevention of diabetic complications.
Authors
Jane E.B. Reusch
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Citations to this article in year 2019 (2)
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Ogunyinka BI, Oyinloye BE, Osunsanmi FO, Kolanisi U, Opoku AR, Kappo AP |
Antioxidants | 2019 |
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Association of Polymorphisms in miRNA Processing Genes With Type 2 Diabetes Mellitus and Its Vascular Complications in a Southern Chinese Population
Wen Z, Zou X, Xie X, Zheng S, Chen X, Zhu K, Dong S, Liang J, Huang X, Liu D, Wang Y, Liu Y, Wu J, Ying Y, Liu K, Lu C, Zhang B, Yang G, Jing C, Nie L |
Frontiers in Endocrinology | 2019 |
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