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The requested article was not found.

Diabetes, microvascular complications, and cardiovascular complications: what is it about glucose?
Jane E.B. Reusch
Jane E.B. Reusch
Published October 1, 2003
Citation Information: J Clin Invest. 2003;112(7):986-988. https://doi.org/10.1172/JCI19902.
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Commentary Article has an altmetric score of 18

Diabetes, microvascular complications, and cardiovascular complications: what is it about glucose?

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Abstract

Glycemic control is the primary mediator of diabetic microvascular complications and also contributes to macrovascular complications. A new study (see related article beginning on page 1049) reveals a previously unrecognized association between oxidant activation of poly(ADP ribose) polymerase (PARP) and upregulation of known mediators of glycemic injury. Inhibitors of PARP may have potential therapeutic roles in the prevention of diabetic complications.

Authors

Jane E.B. Reusch

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