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Jane E.B. Reusch
Published October 1, 2003
Citation Information: J Clin Invest. 2003;112(7):986-988. https://doi.org/10.1172/JCI19902.
Citation Information: J Clin Invest. 2003;112(7):986-988. https://doi.org/10.1172/JCI19902.
Abstract
Glycemic control is the primary mediator of diabetic microvascular complications and also contributes to macrovascular complications. A new study (see related article beginning on page 1049) reveals a previously unrecognized association between oxidant activation of poly(ADP ribose) polymerase (PARP) and upregulation of known mediators of glycemic injury. Inhibitors of PARP may have potential therapeutic roles in the prevention of diabetic complications.
Authors
Jane E.B. Reusch
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Citations to this article in year 2013 (4)
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|---|---|---|
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AM Arbelaez, K Semenkovich, T Hershey |
Pediatric Diabetes | 2013 |
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O-GlcNAc cycling: a link between metabolism and chronic disease.
Bond MR, Hanover JA |
Annual Review of Nutrition | 2013 |
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Protective Effect of Padina arborescens Extract against High Glucose-induced Oxidative Damage in Human Umbilical Vein Endothelial Cells
Park MH, Han JS |
Preventive Nutrition and Food Science | 2013 |
|
Intracellular Adhesion Molecule-1 K469E Gene Polymorphism and Risk of Diabetic Microvascular Complications: A Meta-Analysis
Su X, Chen X, Liu L, Chang X, Yu X, Sun K |
PloS one | 2013 |
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