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Jane E.B. Reusch
Published October 1, 2003
Citation Information: J Clin Invest. 2003;112(7):986-988. https://doi.org/10.1172/JCI19902.
Citation Information: J Clin Invest. 2003;112(7):986-988. https://doi.org/10.1172/JCI19902.
Abstract
Glycemic control is the primary mediator of diabetic microvascular complications and also contributes to macrovascular complications. A new study (see related article beginning on page 1049) reveals a previously unrecognized association between oxidant activation of poly(ADP ribose) polymerase (PARP) and upregulation of known mediators of glycemic injury. Inhibitors of PARP may have potential therapeutic roles in the prevention of diabetic complications.
Authors
Jane E.B. Reusch
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Citation information
Citations to this article in year 2012 (1)
| Title and authors | Publication | Year |
|---|---|---|
|
Cerebral Myogenic Reactivity and Blood Flow in Type 2 Diabetic Rats: Role of Peroxynitrite in Hypoxia-Mediated Loss of Myogenic Tone
Kelly-Cobbs AI, Prakash R, Coucha M, Knight RA, Li W, Ogbi SN, Johnson M, Ergul A |
The Journal of pharmacology and experimental therapeutics | 2012 |
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