Go to JCI Insight
  • About
  • Editors
  • Consulting Editors
  • For authors
  • Publication ethics
  • Publication alerts by email
  • Advertising
  • Job board
  • Contact
  • Clinical Research and Public Health
  • Current issue
  • Past issues
  • By specialty
    • COVID-19
    • Cardiology
    • Gastroenterology
    • Immunology
    • Metabolism
    • Nephrology
    • Neuroscience
    • Oncology
    • Pulmonology
    • Vascular biology
    • All ...
  • Videos
    • Conversations with Giants in Medicine
    • Video Abstracts
  • Reviews
    • View all reviews ...
    • Complement Biology and Therapeutics (May 2025)
    • Evolving insights into MASLD and MASH pathogenesis and treatment (Apr 2025)
    • Microbiome in Health and Disease (Feb 2025)
    • Substance Use Disorders (Oct 2024)
    • Clonal Hematopoiesis (Oct 2024)
    • Sex Differences in Medicine (Sep 2024)
    • Vascular Malformations (Apr 2024)
    • View all review series ...
  • Viewpoint
  • Collections
    • In-Press Preview
    • Clinical Research and Public Health
    • Research Letters
    • Letters to the Editor
    • Editorials
    • Commentaries
    • Editor's notes
    • Reviews
    • Viewpoints
    • 100th anniversary
    • Top read articles

  • Current issue
  • Past issues
  • Specialties
  • Reviews
  • Review series
  • Conversations with Giants in Medicine
  • Video Abstracts
  • In-Press Preview
  • Clinical Research and Public Health
  • Research Letters
  • Letters to the Editor
  • Editorials
  • Commentaries
  • Editor's notes
  • Reviews
  • Viewpoints
  • 100th anniversary
  • Top read articles
  • About
  • Editors
  • Consulting Editors
  • For authors
  • Publication ethics
  • Publication alerts by email
  • Advertising
  • Job board
  • Contact

Citations to this article

Diabetes, microvascular complications, and cardiovascular complications: what is it about glucose?
Jane E.B. Reusch
Jane E.B. Reusch
Published October 1, 2003
Citation Information: J Clin Invest. 2003;112(7):986-988. https://doi.org/10.1172/JCI19902.
View: Text | PDF
Commentary Article has an altmetric score of 18

Diabetes, microvascular complications, and cardiovascular complications: what is it about glucose?

  • Text
  • PDF
Abstract

Glycemic control is the primary mediator of diabetic microvascular complications and also contributes to macrovascular complications. A new study (see related article beginning on page 1049) reveals a previously unrecognized association between oxidant activation of poly(ADP ribose) polymerase (PARP) and upregulation of known mediators of glycemic injury. Inhibitors of PARP may have potential therapeutic roles in the prevention of diabetic complications.

Authors

Jane E.B. Reusch

×

Total citations by year

Year: 2024 2023 2021 2020 2019 2017 2016 2015 2013 2012 2011 2010 2009 2008 2007 2005 Total
Citations: 4 3 2 2 2 3 1 4 4 1 1 4 4 2 1 2 40
Citation information
This citation data is accumulated from CrossRef, which receives citation information from participating publishers, including this journal. Not all publishers participate in CrossRef, so this information is not comprehensive. Additionally, data may not reflect the most current citations to this article, and the data may differ from citation information available from other sources (for example, Google Scholar, Web of Science, and Scopus).

Citations to this article (40)

Title and authors Publication Year
Role and mechanism of miRNA in cardiac microvascular endothelial cells in cardiovascular diseases.
Yan J, Zhong X, Zhao Y, Wang X
Frontiers in Cardiovascular Medicine 2024
Identifying diagnostic indicators for type 2 diabetes mellitus from physical examination using interpretable machine learning approach
Lv X, Luo J, Huang W, Guo H, Bai X, Yan P, Jiang Z, Zhang Y, Jing R, Chen Q, Li M
Frontiers in Endocrinology 2024
The protective effects of alpha-pinene on high glucose-induced oxidative stress and inflammation in HepG2 cells
Choghakhori R, Azadpour M, Abbasnezhad A, Ebrahimzadeh F, Ahmadvand H
Iranian Journal of Basic Medical Sciences 2024
Do modifiable patient factors increase the risk of postoperative complications after total joint arthroplasty?
Baran JV, Rohatgi A, Redden A, Fomunung C, Goguen J, John DQ, Movassaghi A, Jackson GR, Sabesan VJ
Archives of orthopaedic and trauma surgery 2024
Relationship between elevated circulating thrombospondin-1 levels and vascular complications in diabetes mellitus.
Guo N, Yang L, Wan X, Qiu D, Sun W, Ma H
Journal of Diabetes Investigation 2023
A Systematic Review and Meta-analysis of Risk Factors for an Infection After Anterior Cruciate Ligament Reconstruction
Zhang L, Yang R, Mao Y, Fu W
Orthopaedic Journal of Sports Medicine 2023
Joint replacement and human immunodeficiency virus
Salimi M, Mirghaderi P, Mosalamiaghili S, Mohammadi A, Salimi A
World Journal of Virology 2023
Glucose Homeostasis, Hypoglycemia, and the Burnt-Out Diabetes Phenomenon in Kidney Disease
CM Rhee, CP Kovesdy, K Kalantar-Zadeh
Seminars in Nephrology 2021
The Impaired Bioenergetics of Diabetic Cardiac Microvascular Endothelial Cells
Zhang H, Shen Y, Kim IM, Weintraub NL, Tang Y
Frontiers in Endocrinology 2021
Myo -inositol Oxygenase (MIOX) Overexpression Drives the Progression of Renal Tubulointerstitial Injury in Diabetes
I Sharma, F Deng, Y Liao, YS Kanwar
Diabetes 2020
Concentration of proinflammatory cytokines in patients with ulcers as a complication of type 2 diabetes mellitus
Kupczyk D, Bilski R, Przewięźlikowski A, Studziñska R, Woźniak A
2020
Protein Isolate from Parkia biglobosa Seeds Improves Dyslipidaemia and Cardiac Oxidative Stress in Streptozotocin-Induced Diabetic Rats
Ogunyinka BI, Oyinloye BE, Osunsanmi FO, Kolanisi U, Opoku AR, Kappo AP
Antioxidants 2019
Association of Polymorphisms in miRNA Processing Genes With Type 2 Diabetes Mellitus and Its Vascular Complications in a Southern Chinese Population
Wen Z, Zou X, Xie X, Zheng S, Chen X, Zhu K, Dong S, Liang J, Huang X, Liu D, Wang Y, Liu Y, Wu J, Ying Y, Liu K, Lu C, Zhang B, Yang G, Jing C, Nie L
Frontiers in Endocrinology 2019
Intrahepatic vascular changes in non-alcoholic fatty liver disease: Potential role of insulin-resistance and endothelial dysfunction
M Pasarín, JG Abraldes, E Liguori, B Kok, VL Mura
World journal of gastroenterology : WJG 2017
Lipopolysaccharide-binding protein (LBP) reverses the amyloid state of fibrin seen in plasma of type 2 diabetics with cardiovascular co-morbidities
E Pretorius, S Mbotwe, DB Kell
Scientific Reports 2017
PARP inhibition ameliorates nephropathy in an animal model of type 2 diabetes: focus on oxidative stress, inflammation, and fibrosis.
Zakaria EM, El-Maraghy NN, Ahmed AF, Ali AA, El-Bassossy HM
Naunyn-Schmiedeberg's Archives of Pharmacology 2017
Patient-Related Risk Factors for Periprosthetic Joint Infection after Total Joint Arthroplasty: A Systematic Review and Meta-Analysis
Kunutsor SK, Whitehouse MR, Blom AW, Beswick AD
PloS one 2016
Systemic alterations in the metabolome of diabetic NOD mice delineate increased oxidative stress accompanied by reduced inflammation and hypertriglyceremia
J Fahrmann, D Grapov, J Yang, B Hammock, O Fiehn, GI Bell, M Hara
American journal of physiology. Endocrinology and metabolism 2015
Associations of FPG, A1C and disease duration with protein markers of oxidative damage and antioxidative defense in type 2 diabetes and diabetic retinopathy
Reddy VS, Agrawal P, Sethi S, Gupta N, Garg R, Madaan H, Kumar V
Eye 2015
Influence of Acute High Glucose on Protein Abundance Changes in Murine Glomerular Mesangial Cells
Barati MT, Gould JC, Salyer SA, Isaacs S, Wilkey DW, Merchant ML
Journal of Diabetes Research 2015
Matrix Metalloproteinase 9 Gene Promoter (rs 3918242) Mutation Reduces the Risk of Diabetic Microvascular Complications
Zhang Z, Wu X, Cai T, Gao W, Zhou X, Zhao J, Yao J, Shang H, Dong J, Liao L
International journal of environmental research and public health 2015
Glycemic extremes in youth with T1DM: The structural and functional integrity of the developing brain: Glycemic extremes in youth with T1DM
AM Arbelaez, K Semenkovich, T Hershey
Pediatric Diabetes 2013
O-GlcNAc cycling: a link between metabolism and chronic disease.
Bond MR, Hanover JA
Annual Review of Nutrition 2013
Protective Effect of Padina arborescens Extract against High Glucose-induced Oxidative Damage in Human Umbilical Vein Endothelial Cells
Park MH, Han JS
Preventive Nutrition and Food Science 2013
Intracellular Adhesion Molecule-1 K469E Gene Polymorphism and Risk of Diabetic Microvascular Complications: A Meta-Analysis
Su X, Chen X, Liu L, Chang X, Yu X, Sun K
PloS one 2013
Cerebral Myogenic Reactivity and Blood Flow in Type 2 Diabetic Rats: Role of Peroxynitrite in Hypoxia-Mediated Loss of Myogenic Tone
Kelly-Cobbs AI, Prakash R, Coucha M, Knight RA, Li W, Ogbi SN, Johnson M, Ergul A
The Journal of pharmacology and experimental therapeutics 2012
Transcriptional and Post-translational Modulation of myo-Inositol Oxygenase by High Glucose and Related Pathobiological Stresses
Nayak B, Kondeti VK, Xie P, Lin S, Viswakarma N, Raparia K, Kanwar YS
The Journal of biological chemistry 2011
Insulin-dependent diabetes mellitus in mice does not alter liver heparan sulfate
JR Bishop, E Foley, R Lawrence, JD Esko
The Journal of biological chemistry 2010
Pathobiology of renal-specific oxidoreductase/myo-inositol oxygenase in diabetic nephropathy: its implications in tubulointerstitial fibrosis
P Xie, L Sun, PJ Oates, SK Srivastava, YS Kanwar
American journal of physiology. Renal physiology 2010
An accurate spectroscopic calibration for non-invasive glucose monitoring by modeling the physiological glucose dynamics
Barman I, Kong CR, Singh GP, Dasari RR, Feld MS
Analytical Chemistry 2010
Aspirin for Primary Prevention of Cardiovascular Events in People With Diabetes: A position statement of the American Diabetes Association, a scientific statement of the American Heart Association, and an expert consensus document of the American College of Cardiology Foundation
Pignone M, Alberts MJ, Colwell JA, Cushman M, Inzucchi SE, Mukherjee D, Rosenson RS, Williams CD, Wilson PW, Kirkman MS
Diabetes care 2010
Pulmonary surfactant: an immunological perspective
ZC Chroneos, Z Sever-Chroneos, VL Shepherd
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2009
Role of nitrosative stress in the pathogenesis of diabetic vascular dysfunction
C Szabo
British Journal of Pharmacology 2009
Problems associated with glucose toxicity: role of hyperglycemia-induced oxidative stress
S Kawahito, H Kitahata, S Oshita
World journal of gastroenterology : WJG 2009
Glycation Isotopic Labeling with 13C-Reducing Sugars for Quantitative Analysis of Glycated Proteins in Human Plasma
Priego-Capote F, Scherl A, Müller M, Waridel P, Lisacek F, Sanchez JC
Molecular & cellular proteomics : MCP 2009
Regulation of plasma fructose and mortality in mice by the aldose reductase inhibitor lidorestat
HL Noh, Y Hu, TS Park, T DiCioccio, AJ Nichols, K Okajima, S Homma, IJ Goldberg
The Journal of pharmacology and experimental therapeutics 2008
Aldose Reductase Regulates High Glucose-Induced Ectodomain Shedding of Tumor Necrosis Factor (TNF)-α via Protein Kinase C-δ and TNF-α Converting Enzyme in Vascular Smooth Muscle Cells
AB Reddy, KV Ramana, S Srivastava, A Bhatnagar, SK Srivastava
Endocrinology 2008
Early diabetic neuropathy: Triggers and mechanisms
Dobretsov M, Romanovsky D, Stimers JR
World journal of gastroenterology : WJG 2007
Role of Poly(ADP-Ribose) Polymerase-1 Activation in the Pathogenesis of Diabetic Complications: Endothelial Dysfunction, as a Common Underlying Theme
P Pacher, C Szabó
Antioxidants & Redox Signaling 2005
Role of nitrosative stress and peroxynitrite in the pathogenesis of diabetic complications. Emerging new therapeutical strategies.
Pacher P, Obrosova IG, Mabley JG, Szabó C
Current medicinal chemistry 2005

← Previous 1 2 Next →

Advertisement

Copyright © 2025 American Society for Clinical Investigation
ISSN: 0021-9738 (print), 1558-8238 (online)

Sign up for email alerts

Picked up by 1 news outlets
Referenced in 1 policy sources
Posted by 2 X users
Referenced in 2 patents
On 1 Facebook pages
21 readers on Mendeley
2 readers on CiteULike
See more details