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Citations to this article

Reperfusion injury induces apoptosis in rabbit cardiomyocytes.
R A Gottlieb, … , B M Babior, R L Engler
R A Gottlieb, … , B M Babior, R L Engler
Published October 1, 1994
Citation Information: J Clin Invest. 1994;94(4):1621-1628. https://doi.org/10.1172/JCI117504.
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Research Article Article has an altmetric score of 6

Reperfusion injury induces apoptosis in rabbit cardiomyocytes.

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Abstract

The most effective way to limit myocardial ischemic necrosis is reperfusion, but reperfusion itself may result in tissue injury, which has been difficult to separate from ischemic injury. This report identifies elements of apoptosis (programmed cell death) in myocytes as a response to reperfusion but not ischemia. The hallmark of apoptosis, nucleosomal ladders of DNA fragments (approximately 200 base pairs), was detected in ischemic/reperfused rabbit myocardial tissue but not in normal or ischemic-only rabbit hearts. Granulocytopenia did not prevent nucleosomal DNA cleavage. In situ nick end labeling demonstrated DNA fragmentation predominantly in myocytes. The pattern of nuclear chromatin condensation was distinctly different in reperfused than in persistently ischemic tissue by transmission electron microscopy. Apoptosis may be a specific feature of reperfusion injury in cardiac myocytes, leading to late cell death.

Authors

R A Gottlieb, K O Burleson, R A Kloner, B M Babior, R L Engler

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Journal of traditional and complementary medicine 2017
Heat shock protein 70 protects cardiomyocytes through suppressing SUMOylation and nucleus translocation of phosphorylated eukaryotic elongation factor 2 during myocardial ischemia and reperfusion
C Zhang, X Liu, J Miao, S Wang, L Wu, D Yan, J Li, W Guo, X Wu, A Shen
Apoptosis 2017
PPARγ Alleviates Right Ventricular Failure Secondary to Pulmonary Arterial Hypertension in Rats
Y Xu, Q Gu, N Liu, Y Yan, X Yang, Y Hao, C Qu
International Heart Journal 2017
Substance P Attenuates Hypoxia/Reoxygenation-Induced Apoptosis Via the Akt Signalling Pathway and the NK1-Receptor in H9C2Cells
Y Xu, Q Gu, J Tang, Y Qian, X Tan, Z Yu, C Qu
Heart, lung & circulation 2017
Cardioprotective effects of combined therapy with diltiazem and superoxide dismutase on myocardial ischemia-reperfusion injury in rats
C Chen, W Lu, G Wu, L Lv, W Chen, L Huang, X Wu, N Xu, Y Wu
Life Sciences 2017
Minireview: Syndecans and their crucial roles during tissue regeneration
H Chung, HA Multhaupt, ES Oh, JR Couchman
FEBS Letters 2016
Cox-2 Inhibition Protects against Hypoxia/Reoxygenation-Induced Cardiomyocyte Apoptosis via Akt-Dependent Enhancement of iNOS Expression
L Pang, Y Cai, EH Tang, D Yan, R Kosuru, H Li, MG Irwin, H Ma, Z Xia
Oxidative medicine and cellular longevity 2016
Myocardial apoptosis in heart disease: does the emperor have clothes?
JJ Corbalan, DE Vatner, SF Vatner
Basic Research in Cardiology 2016
Mitochondrial Function, Biology, and Role in Disease: A Scientific Statement From the American Heart Association
E Murphy, H Ardehali, RS Balaban, F DiLisa, GW Dorn, RN Kitsis, K Otsu, P Ping, R Rizzuto, MN Sack, D Wallace, RJ Youle
Circulation research 2016
The role of AMPK in cardiomyocyte health and survival
SC Bairwa, N Parajuli, JR Dyck
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease 2016
NPR3 protects cardiomyocytes from apoptosis through inhibition of cytosolic BRCA1 and TNF-α
D Lin, Y Chai, R Izadpanah, SE Braun, E Alt
Cell cycle (Georgetown, Tex.) 2016
Studies on the role of apoptosis after transient myocardial ischemia: genetic deletion of the executioner caspases-3 and -7 does not limit infarct size and ventricular remodeling
J Inserte, M Cardona, M Poncelas-Nozal, V Hernando, Ú Vilardosa, D Aluja, VM Parra, D Sanchis, D Garcia-Dorado
Basic Research in Cardiology 2016
Myocardial protective effects of a c-Jun N-terminal kinase inhibitor in rats with brain death
W Guo, S Cao, B Yan, G Zhang, J Li, Y Zhao, S Zhang
Journal of Cellular and Molecular Medicine 2016
Therapeutic synergy and complementarity for ischemia/reperfusion injury: β1-adrenergic blockade and phosphodiesterase-3 inhibition
MH Huang, KK Poh, HC Tan, FG Welt, CY Lui
International Journal of Cardiology 2016
Targeting the Innate Immune Response to Improve Cardiac Graft Recovery after Heart Transplantation: Implications for the Donation after Cardiac Death
S Toldo, M Quader, F Salloum, E Mezzaroma, A Abbate
International journal of molecular sciences 2016
Pathobiology of Ischemic Heart Disease: Past, Present and Future
LM Buja, RS Heide
Cardiovascular Pathology 2016
Soluble TNF-related apoptosis induced ligand (sTRAIL) is augmented by Post-Conditioning and correlates to infarct size and left ventricle dysfunction in STEMI patients: a substudy from a randomized clinical trial
A Luz, M Santos, R Magalhães, JC Oliveira, A Pacheco, J Silveira, S Cabral, S Torres, AF Leite-Moreira, H Carvalho
Heart and Vessels 2016
Cellular apoptosis in the cardiorenal axis
GM Virzì, A Clementi, C Ronco
Heart Failure Reviews 2016
Cardioprotective Effects of Phenylethanoid Glycoside-rich Extract from Cistanche deserticola in Ischemia-Reperfusion–Induced Myocardial Infarction in Rats
Q Yu, X Li, X Cao
Annals of Vascular Surgery 2016
Clematichinenoside (AR) Attenuates Hypoxia/Reoxygenation-Induced H9c2 Cardiomyocyte Apoptosis via a Mitochondria-Mediated Signaling Pathway
H Ding, R Han, X Chen, W Fang, M Liu, X Wang, Q Wei, N Kodithuwakku, Y Li
Molecules (Basel, Switzerland) 2016
A cardiac myocyte-restricted Lin28/let-7 regulatory axis promotes hypoxia-mediated apoptosis by inducing the AKT signaling suppressor PIK3IP1
S Joshi, J Wei, NH Bishopric
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease 2016
Liraglutide protects cardiac microvascular endothelial cells against hypoxia/reoxygenation injury through the suppression of the SR-Ca2+–XO–ROS axis via activation of the GLP-1R/PI3K/Akt/survivin pathways
Y Zhang, H Zhou, W Wu, C Shi, S Hu, T Yin, Q Ma, T Han, Y Zhang, F Tian, Y Chen
Free radical biology & medicine 2016
Acute Stress Decreases but Chronic Stress Increases Myocardial Sensitivity to Ischemic Injury in Rodents
ED Eisenmann, BR Rorabaugh, PR Zoladz
Frontiers in Psychiatry 2016
Aleglitazar, a Balanced Dual PPARα and -γ Agonist, Protects the Heart Against Ischemia-Reperfusion Injury
J Qian, H Chen, Y Birnbaum, MK Nanhwan, M Bajaj, Y Ye
Cardiovascular Drugs and Therapy 2016
Effects of Shenqi Fuzheng injection on Fas/FasL protein expression levels in the cardiomyocytes of a mouse model of viral myocarditis
T Wu, J Chen, L Fan, W Xie, C Xu, H Wang
Experimental and therapeutic medicine 2016
Lidocaine Enhances Contractile Function of Ischemic Myocardial Regions in Mouse Model of Sustained Myocardial Ischemia
B Müller-Edenborn, G Kania, E Osto, P Jakob, N Krasniqi, B Beck-Schimmer, P Blyszczuk, U Eriksson, J Calvert
PloS one 2016
Phosphorylated eEF2 is SUMOylated and induces cardiomyocyte apoptosis during myocardial ischemia reperfusion
C Zhang, X Liu, C Zhang, J Li, W Guo, D Yan, C Yang, J Zhao, X Wu, J Shi
Journal of Cardiology 2016
NOX2 Antisense Attenuates Hypoxia-Induced Oxidative Stress and Apoptosis in Cardiomyocyte
B Yu, F Meng, Y Yang, D Liu, K Shi
International journal of medical sciences 2016
3D Printed Stem-Cell-Laden, Microchanneled Hydrogel Patch for the Enhanced Release of Cell-Secreting Factors and Treatment of Myocardial Infarctions
MR Melhem, J Park, L Knapp, L Reinkensmeyer, C Cvetkovic, J Flewellyn, MK Lee, TW Jensen, R Bashir, H Kong, LB Schook
ACS Biomaterials Science & Engineering 2016
Naringenin ameliorates hypoxia/reoxygenation-induced endoplasmic reticulum stress-mediated apoptosis in H9c2 myocardial cells: involvement in ATF6, IRE1α and PERK signaling activation
JY Tang, P Jin, Q He, LH Lu, JP Ma, WL Gao, HP Bai, J Yang
Molecular and Cellular Biochemistry 2016
Mitochondrial phosphatase PGAM5 regulates Keap1-mediated Bcl-xL degradation and controls cardiomyocyte apoptosis driven by myocardial ischemia/reperfusion injury
C Yang, X Liu, F Yang, W Zhang, Z Chen, D Yan, Q You, X Wu
In vitro cellular & developmental biology. Animal 2016
Chronic type-I diabetes could not impede the anti-inflammatory and anti-apoptotic effects of combined postconditioning with ischemia and cyclosporine A in myocardial reperfusion injury
R Badalzadeh, A Azimi, A Alihemmati, B Yousefi
Journal of Physiology and Biochemistry 2016
Cardiomyocytes – Active Players in Cardiac Disease
KD Schlüter
Cardiomyocytes – Active Players in Cardiac Disease 2016
ADORA2b Signaling in Cardioprotection
Jennifer Gile, Tobias Eckle
Journal of nature and science 2016
TWEAK protects cardiomyocyte against apoptosis in a PI3K/AKT pathway dependent manner
Bin Yang, Ping Yan, Hui Gong, Lin Zuo, Ying Shi, Jian Guo, Rui Guo, Jun Xie, Bao Li
American journal of translational research 2016
Hydrogen Peroxide‐Responsive Nanoparticle Reduces Myocardial Ischemia/Reperfusion Injury
S Bae, M Park, C Kang, S Dilmen, TH Kang, DG Kang, Q Ke, SU Lee, D Lee, PM Kang
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease 2016
Myocardial reverse remodeling: how far can we rewind?
PG Rodrigues, AF Leite-Moreira, I Falcão-Pires
American journal of physiology. Heart and circulatory physiology 2016
Coronary Graft Failure
IC Ţintoiu, MJ Underwood, SP Cook, H Kitabata, A Abbas
2016
Macrophages mediate cardioprotective cellular postconditioning in acute myocardial infarction
Geoffrey de Couto, Wenxie Liu, Eleni Tseliou, Baiming Sun, Nupur Makkar, Hideaki Kanazawa, Moshe Arditi, Eduardo Marbán
Journal of Clinical Investigation 2015
Comprehensive Physiology
NG Frangogiannis
Comprehensive Physiology 2015
Abnormalities in Alternative Splicing of Apoptotic Genes and Cardiovascular Diseases
Z Dlamini, S Tshidino, R Hull
International journal of molecular sciences 2015
Na+–Ca2+ exchanger targeting miR-132 prevents apoptosis of cardiomyocytes under hypoxic condition by suppressing Ca2+ overload
S Hong, J Lee, HH Seo, CY Lee, KJ Yoo, SM Kim, S Lee, KC Hwang, E Choi
Biochemical and Biophysical Research Communications 2015
TGF-β improves myocardial function and prevents apoptosis induced by anoxia–reoxygenation, through the reduction of endoplasmic reticulum stress
Y Wang, L Zong, X Wang
Canadian Journal of Physiology and Pharmacology 2015
Attenuated SAG expression exacerbates 4-hydroxy-2-nonenal-induced apoptosis and hypertrophy of H9c2 cardiomyocytes
JH Park, JH Lee, JW Park
Free Radical Research 2015
Inhibition of p38 MAPK activation protects cardiac mitochondria from ischemia/reperfusion injury
S Kumphune, S Surinkaew, SC Chattipakorn, N Chattipakorn
Pharmaceutical Biology 2015
Up-regulation of iNOS by hypoxic postconditioning inhibits H9c2 cardiomyocyte apoptosis induced by hypoxia/re-oxygenation
H Zhao, R Yang, Y Shi, W Yang, Q Zeng, G Zhao, X Wang
Acta Biochimica et Biophysica Sinica 2015
Mechanical Tissue Resuscitation (MTR): A Nonpharmacological Approach to Treatment of Acute Myocardial Infarction: MTR HAS WIDE THERAPEUTIC WINDOW
JE Jordan, BD Pereira, MR Lane, MJ Morykwas, M McGee, LC Argenta
Journal of Cardiac Surgery 2015
High-molecular-weight polyethylene glycol inhibits myocardial ischemia–reperfusion injury in vivo
X Xu, JL Philip, MA Razzaque, JW Lloyd, CM Muller, SA Akhter
The Journal of Thoracic and Cardiovascular Surgery 2015
Modulation of p38 kinase by DUSP4 Is important in regulating cardiovascular function under oxidative stress
A Barajas-Espinosa, A Basye, MG Angelos, CA Chen
Free radical biology & medicine 2015
Secreted tyrosine sulfated-eIF5A mediates oxidative stress-induced apoptosis
Y Seko, T Fujimura, T Yao, H Taka, R Mineki, K Okumura, K Murayama
Scientific Reports 2015
Reactive oxygen species-activated nanomaterials as theranostic agents
KS Kim, D Lee, CG Song, PM Kang
Nanomedicine 2015
The role and modulation of autophagy in experimental models of myocardial ischemia-reperfusion injury
Carol Chen-Scarabelli, Pratik R Agrawal, Louis Saravolatz, Cadigia Abuniat, Gabriele Scarabelli, Anastasis Stephanou, Leena Loomba, Jagat Narula, Tiziano M Scarabelli, Richard Knight
Journal of Geriatric Cardiology 2015
Cell Death in the Cardiac Myocyte
T Marunouchi, K Tanonaka
Biological & Pharmaceutical Bulletin 2015
Tyrosol Prevents Ischemia/Reperfusion-Induced Cardiac Injury in H9c2 Cells: Involvement of ROS, Hsp70, JNK and ERK, and Apoptosis
L Sun, H Fan, L Yang, L Shi, Y Liu
Molecules (Basel, Switzerland) 2015
DNA Repair Gene Polymorphism and the Risk of Mitral Chordae Tendineae Rupture
AK Yigin, MB Vatan, R Akdemir, MN Aksoy, MA Cakar, H Kilic, U Erkorkmaz, K Karacan, S Kaleli
Disease Markers 2015
Correlation between apoptosis and left ventricular remodeling in subacute phase of myocardial ischemia and reperfusion
H Wakabayashi, J Taki, A Inaki, K Shiba, I Matsunari, S Kinuya
EJNMMI Research 2015
Dihydropyridines’ metabolites-induced early apoptosis after myocardial infarction in rats; new outlook on preclinical study with M-2 and M-3
KA Mitręga, J Nożyński, M Porc, AM Spałek, TF Krzemiński
Apoptosis 2015
NF45 inhibits cardiomyocyte apoptosis following myocardial ischemia-reperfusion injury
X Liu, C Zhang, L Qian, C Zhang, K Wu, C Yang, D Yan, X Wu, J Shi
Pathology - Research and Practice 2015
Mechanisms of oxidative stress and myocardial protection during open-heart surgery
NG Baikoussis, NA Papakonstantinou, C Verra, G Kakouris, M Chounti, P Hountis, P Dedeilias, M Argiriou
Annals of Cardiac Anaesthesia 2015
Acute myocardial infarction and myocardial ischemia-reperfusion injury: a comparison
Satwat Hashmi, Suhail Al-Salam
International journal of clinical and experimental pathology 2015
Apoptosis, ANUP, Chromogranin A, PGP 9.5, Endothelins and VEGF in Acquired Heart Diseases: Review of Literature
E Kulmane, M Pilmane, R Lacis
Acta Chirurgica Latviensis 2015
Cardiac Cytoarchitecture
E Ehler
2015
Role of copper in regression of cardiac hypertrophy
L Zheng, P Han, J Liu, R Li, W Yin, T Wang, W Zhang, YJ Kang
Pharmacology & Therapeutics 2014
Exogenous midkine administration prevents cardiac remodeling in pacing-induced congestive heart failure of rabbits
M Harada, M Hojo, K Kamiya, K Kadomatsu, T Murohara, I Kodama, M Horiba
Heart and Vessels 2014
Small molecules, big effects: the role of microRNAs in regulation of cardiomyocyte death
J Skommer, I Rana, FZ Marques, W Zhu, Z Du, FJ Charchar
Cell Death and Disease 2014
Comprehensive Physiology
SN Cheuvront, RW Kenefick
Comprehensive Physiology 2014
Reperfusion Therapy with Low-Dose Insulin or Insulin-Like Growth Factor 2; Myocardial Function and Infarct Size in a Porcine Model of Ischaemia and Reperfusion
PR Salminen, GO Dahle, CA Moen, A Wergeland, AK Jonassen, R Haaverstad, K Matre, K Grong
Basic & Clinical Pharmacology & Toxicology 2014
Naloxone Postconditioning Alleviates Rat Myocardial Ischemia Reperfusion Injury by Inhibiting JNK Activity
A Xia, Z Xue, W Wang, T Zhang, T Wei, X Sha, Y Ding, W Zhou
The Korean Journal of Physiology & Pharmacology 2014
Both Castration and Goserelin Acetate Ameliorate Myocardial Ischemia Reperfusion Injury and Apoptosis in Male Rats
NR Hadi, FG Yusif, M Yousif, KK Jaen
ISRN Pharmacology 2014
Functional O-GlcNAc modifications: Implications in molecular regulation and pathophysiology
K Vaidyanathan, S Durning, L Wells
Critical Reviews in Biochemistry and Molecular Biology 2014
Protective effect of picroside II on myocardial ischemia reperfusion injury in rats
N Wu, W Li, W Shu, D Jia
Drug design, development and therapy 2014
Cardioprotective effect of betulinic Acid on myocardial ischemia reperfusion injury in rats
A Xia, Z Xue, Y Li, W Wang, J Xia, T Wei, J Cao, W Zhou
Evidence-Based Complementary and Alternative Medicine 2014
Calpain system and its involvement in myocardial ischemia and reperfusion injury
C Neuhof, H Neuhof
World journal of cardiology 2014
Anti-apoptosis effect of polysaccharide isolated from the seeds of Cuscuta chinensis Lam on cardiomyocytes in aging rats
SL Sun, L Guo, YC Ren, B Wang, RH Li, YS Qi, H Yu, ND Chang, MH Li, HS Peng
Molecular Biology Reports 2014
Novel therapeutic strategies for ischemic heart disease
AJ Perricone, RS Heide
Pharmacological Research 2014
Myofibrillogenesis regulator-1 attenuated hypoxia/reoxygenation-induced apoptosis by inhibiting the PERK/Nrf2 pathway in neonatal rat cardiomyocytes
TQ Tao, XR Wang, M Liu, FF Xu, XH Liu
Apoptosis 2014
Ecdysterone protects gerbil brain from temporal global cerebral ischemia/reperfusion injury via preventing neuron apoptosis and deactivating astrocytes and microglia cells
W Wang, T Wang, WY Feng, ZY Wang, MS Cheng, YJ Wang
Neuroscience Research 2014
Magnesium lithospermate B improves myocardial function and prevents simulated ischemia/reperfusion injury-induced H9c2 cardiomyocytes apoptosis through Akt-dependent pathway
W Quan, B Wu, Y Bai, X Zhang, J Yin, M Xi, Y Guan, Q Shao, Y Chen, Q Wu, A Wen
Journal of Ethnopharmacology 2014
Ischaemic conditioning strategies for the nephrologist: a promise lost in translation?
K McCafferty, C Byrne, MM Yaqoob
Nephrology Dialysis Transplantation 2014
Noninvasive Molecular Imaging of Cell Death in Myocardial Infarction using 111In-GSAO
N Tahara, HR Zandbergen, HJ de Haas, A Petrov, R Pandurangi, T Yamaki, J Zhou, T Imaizumi, RH Slart, M Dyszlewski, T Scarabelli, A Kini, C Reutelingsperger, N Narula, V Fuster, J Narula
Scientific Reports 2014
SPRC protects hypoxia and re-oxygenation injury by improving rat cardiac contractile function and intracellular calcium handling
YH Liang, YQ Shen, W Guo, YZ Zhu
Nitric Oxide 2014
Protein kinase C signaling pathway involvement in cardioprotection during isoflurane pretreatment
H Li, XE Lang
Molecular medicine reports 2014
Overexpression of the muscle-specific protein, melusin, protects from cardiac ischemia/reperfusion injury
C Penna, M Brancaccio, F Tullio, C Rubinetto, MG Perrelli, C Angotti, P Pagliaro, G Tarone
Basic Research in Cardiology 2014
Molecular identity of the mitochondrial permeability transition pore and its role in ischemia-reperfusion injury
G Morciano, C Giorgi, M Bonora, S Punzetti, R Pavasini, MR Wieckowski, G Campo, P Pinton
Journal of Molecular and Cellular Cardiology 2014
The protective effect of hispidin against hydrogen peroxide-induced apoptosis in H9c2 cardiomyoblast cells through Akt/GSK-3β and ERK1/2 signaling pathway
DE Kim, B Kim, HS Shin, HJ Kwon, ES Park
Experimental Cell Research 2014
Protective effects of crocetin pretreatment on myocardial injury in an ischemia/reperfusion rat model
Y Wang, J Sun, C Liu, C Fang
European Journal of Pharmacology 2014
Atorvastatin ameliorates myocardial ischemia/reperfusion injury through attenuation of endoplasmic reticulum stress-induced apoptosis
Hui Wu, Qizhu Tang, Jun Yang, Jiawang Ding, Ming Ye, Wusong Dong
International journal of clinical and experimental medicine 2014
Intracoronary insulin administered at reperfusion in a porcine model of acute coronary syndrome
PR Salminen, GO Dahle, CA Moen, AK Jonassen, R Haaverstad, K Matre, K Grong
European heart journal. Acute cardiovascular care 2014
Introduction to Translational Cardiovascular Research
DV Cokkinos
2014
MFG-E8 and Inflammation
P Wang
2014
Fluorescence tomography of rapamycin-induced autophagy and cardioprotection in vivo
HH Chen, C Mekkaoui, H Cho, S Ngoy, B Marinelli, P Waterman, M Nahrendorf, R Liao, L Josephson, DE Sosnovik
Circulation. Cardiovascular imaging 2013
Cell death in the myocardium: my heart won't go on
AM Orogo, ÅB Gustafsson
IUBMB Life (International Union of Biochemistry and Molecular Biology: Life) 2013
Apoptosis repressor with a CARD domain (ARC) restrains Bax-mediated pathogenesis in dystrophic skeletal muscle
J Davis, JQ Kwong, RN Kitsis, JD Molkentin
PloS one 2013
Endocrine protection of ischemic myocardium by FGF21 from the liver and adipose tissue
SQ Liu, D Roberts, A Kharitonenkov, B Zhang, SM Hanson, YC Li, LQ Zhang, YH Wu
Scientific Reports 2013
Soluble TNF receptors are associated with infarct size and ventricular dysfunction in ST-elevation myocardial infarction
L Nilsson, A Szymanowski, E Swahn, L Jonasson
PloS one 2013
Dynasore protects mitochondria and improves cardiac lusitropy in Langendorff perfused mouse heart
D Gao, L Zhang, R Dhillon, TT Hong, RM Shaw, J Zhu
PloS one 2013
Ginsenoside RK3 Prevents Hypoxia-Reoxygenation Induced Apoptosis in H9c2 Cardiomyocytes via AKT and MAPK Pathway
J Sun, G Sun, X Meng, H Wang, M Wang, M Qin, B Ma, Y Luo, Y Yu, R Chen, Q Ai, X Sun
Evidence-Based Complementary and Alternative Medicine 2013
Bioactive Food as Dietary Interventions for Cardiovascular Disease
H Hwang, JP Konhilas
Bioactive Food as Dietary Interventions for Cardiovascular Disease 2013
Danshen mediates through estrogen receptors to activate Akt and inhibit apoptosis effect of Leu27IGF-II-induced IGF-II receptor signaling activation in cardiomyoblasts
YS Weng, WW Kuo, YM Lin, CH Kuo, BS Tzang, FJ Tsai, CH Tsai, JA Lin, DJ Hsieh, CY Huang
Food and Chemical Toxicology 2013
Valsartan attenuates oxidative stress and NF-κB activation and reduces myocardial apoptosis after ischemia and reperfusion
B Wu, R Lin, R Dai, C Chen, H Wu, M Hong
European Journal of Pharmacology 2013
Inhibition of apoptosis by the intrinsic but not the extrinsic apoptotic pathway in myocardial ischemia-reperfusion
AV Kristen, K Ackermann, S Buss, L Lehmann, PA Schnabel, A Haunstetter, HA Katus, SE Hardt
Cardiovascular Pathology 2013
Mesenchymal stem cell exosome ameliorates reperfusion injury through proteomic complementation
RC Lai, RW Yeo, KH Tan, SK Lim
Regenerative Medicine 2013
Cardiomyocyte apoptosis in the failing heart — A critical review from definition and classification of cell death
G Takemura, M Kanoh, S Minatoguchi, H Fujiwara
International Journal of Cardiology 2013
The Comparison of the Effects of Bretschneider's Histidine-Tryptophan-Ketoglutarate and Conventional Crystalloid Cardioplegia on Pediatric Myocardium at Tissue Level: Bretschneider's HTK and Conventional Crystalloid Cardioplegia
O Korun, M Özkan, A Terzi, G Aşkın, A Sezgin, S Aşlamacı
Artificial Organs 2013
Targeting cell death in the reperfused heart: Pharmacological approaches for cardioprotection
MI Oerlemans, S Koudstaal, SA Chamuleau, DP de Kleijn, PA Doevendans, JP Sluijter
International Journal of Cardiology 2013
Haschek and Rousseaux's Handbook of Toxicologic Pathology
BR Berridge, JF van Vleet, E Herman
Haschek and Rousseaux's Handbook of Toxicologic Pathology 2013
Effect and Mechanism of Propofol on Myocardial Ischemia Reperfusion Injury in Type 2 Diabetic Rats
C Lin, H Sui, J Gu, X Yang, L Deng, W Li, W Ding, D Li, Y Yang
Microvascular Research 2013
Involvement of cardiomyocyte apoptosis in myocardial injury of hereditary epileptic rats
F Chen, Y Cao, H Qi, L Li, W Huang, Y Wang, H Sun
Canadian Journal of Physiology and Pharmacology 2013
Hydrogen peroxide-responsive copolyoxalate nanoparticles for detection and therapy of ischemia–reperfusion injury
D Lee, S Bae, Q Ke, J Lee, B Song, SA Karumanchi, G Khang, HS Choi, PM Kang
Journal of Controlled Release 2013
Protective effect of CDP-choline on ischemia-reperfusion-induced myocardial tissue injury in rats
C Coskun, B Avci, M Yalcin, A Yermezler, MS Yilmaz, V Savci
Irish Journal of Medical Science 2013
Alpinetin activates the δ receptor instead of the κ and μ receptor pathways to protect against rat myocardial cell apoptosis
C Suo, L Sun, S Yang
Experimental and therapeutic medicine 2013
p53's choice of myocardial death or survival: Oxygen protects infarct myocardium by recruiting p53 on NOS3 promoter through regulation of p53-Lys(118) acetylation
R Gogna, E Madan, M Khan, U Pati, P Kuppusamy
EMBO Molecular Medicine 2013
H2O2-responsive molecularly engineered polymer nanoparticles as ischemia/reperfusion-targeted nanotherapeutic agents
D Lee, S Bae, D Hong, H Lim, JH Yoon, O Hwang, S Park, Q Ke, G Khang, PM Kang
Scientific Reports 2013
Z-disc transcriptional coupling, sarcomeroptosis and mechanoptosis [corrected]
R Knöll, B Buyandelger
Cell Biochemistry and Biophysics 2013
Combination of Epinephrine with Esmolol Attenuates Post-Resuscitation Myocardial Dysfunction in a Porcine Model of Cardiac Arrest
Q Zhang, CS Li, X Chen
PloS one 2013
Gene Therapy
S Nimesh
Gene Therapy 2013
Soluble TNF Receptors Are Associated with Infarct Size and Ventricular Dysfunction in ST-Elevation Myocardial Infarction
L Nilsson, A Szymanowski, E Swahn, L Jonasson, AJ Marian
PloS one 2013
Dynasore Protects Mitochondria and Improves Cardiac Lusitropy in Langendorff Perfused Mouse Heart
D Gao, L Zhang, R Dhillon, TT Hong, RM Shaw, J Zhu, R Mohanraj
PloS one 2013
Apoptosis Repressor with a CARD Domain (ARC) Restrains Bax-Mediated Pathogenesis in Dystrophic Skeletal Muscle
J Davis, JQ Kwong, RN Kitsis, JD Molkentin, MA Sussman
PloS one 2013
Pediatric and Congenital Cardiology, Cardiac Surgery and Intensive Care
EM da Cruz, D Ivy, J Jaggers
Pediatric and Congenital Cardiology, Cardiac Surgery and Intensive Care 2013
Isoflurane Preconditioning Confers Cardioprotection by Activation of ALDH2
XE Lang, X Wang, KR Zhang, JY Lv, JH Jin, QS Li, SR Singh
PloS one 2013
Prognostic Value of TNF-Related Apoptosis Inducing Ligand (TRAIL) in Acute Coronary Syndrome Patients
P Osmancik, E Teringova, P Tousek, P Paulu, P Widimsky, A Abbate
PloS one 2013
Cardiac Remodeling
BI Jugdutt, NS Dhalla
2013
Regression of pathological cardiac hypertrophy: Signaling pathways and therapeutic targets
J Hou, YJ Kang
Pharmacology & Therapeutics 2012
Genomics in cardiovascular diseases: analysis of the importance of the toll-like receptor signaling pathway
J Bustamante, E Tamayo, J Herreros
International journal of general medicine 2012
Adora2b Signaling on Bone Marrow Derived Cells Dampens Myocardial Ischemia-Reperfusion Injury:
M Koeppen, PN Harter, S Bonney, M Bonney, S Reithel, C Zachskorn, M Mittelbronn, T Eckle
Anesthesiology 2012
A Soluble Receptor for Advanced Glycation End-Products Inhibits Hypoxia/Reoxygenation-Induced Apoptosis in Rat Cardiomyocytes via the Mitochondrial Pathway
C Guo, X Zeng, J Song, M Zhang, H Wang, X Xu, F Du, B Chen
International journal of molecular sciences 2012
Imaging Myocardial Ischemia and Reperfusion Injury via Cy5.5-Annexin V
R Tian, DF Pan
Nuclear Medicine and Molecular Imaging 2012
MicroRNA-15a/b are up-regulated in response to myocardial ischemia/reperfusion injury
LF Liu, Z Liang, ZR Lv, XH Liu, J Bai, J Chen, C Chen, Y Wang
Journal of Geriatric Cardiology 2012
Local Oxidative Stress Expansion through Endothelial Cells – A Key Role for Gap Junction Intercellular Communication
I Feine, I Pinkas, Y Salomon, A Scherz
PloS one 2012
Intracoronary Levosimendan during Ischemia Prevents Myocardial Apoptosis
M Malmberg, T Vähäsilta, A Saraste, JW Koskenvuo, JP Pärkkä, K Leino, T Laitio, C Stark, A Heikkilä, P Saukko, T Savunen
Frontiers in physiology 2012
Methods in Enzymology
JD Stone, AS Chervin, DH Aggen, DM Kranz
Protein Engineering for Therapeutics Part B 2012
Contrast-enhanced MRI of murine myocardial infarction - Part I : CONTRAST-ENHANCED MRI OF MURINE MYOCARDIAL INFARCTION
T Geelen, LE Paulis, BF Coolen, K Nicolay, GJ Strijkers
NMR in Biomedicine 2012
Extracellular and intracellular proteases in cardiac dysfunction due to ischemia–reperfusion injury
AL Müller, LV Hryshko, NS Dhalla
International Journal of Cardiology 2012
Liposomes for cardiovascular targeting
TS Levchenko, WC Hartner, VP Torchilin
Therapeutic Delivery 2012
GLP-1 and cardioprotection: from bench to bedside
S Ravassa, A Zudaire, J Diez
Cardiovascular Research 2012
Muscle
ML Martin, SL Belmonte, R Ram, FA Kamal, BC Blaxall
Muscle 2012
Liposomes in diagnosis and treatment of cardiovascular disorders
TS Levchenko, WC Hartner, VP Torchilin
Methodist DeBakey Cardiovascular Journal 2012
Protection of the ischemic myocardium during the reperfusion: between hope and reality
JC Bopassa
American Journal of Cardiovascular Disease 2012
Single intravenous low-dose injections of connexin 43 mimetic peptides protect ischemic heart in vivo against myocardial infarction
G Hawat, P Hélie, G Baroudi
Journal of Molecular and Cellular Cardiology 2012
Delayed Postconditioning: Not Too Late?
S Barrère-Lemaire, J Nargeot, C Piot
Trends in Cardiovascular Medicine 2012
Enhanced cell survival and diminished apoptotic response to simulated ischemia–reperfusion in H9c2 cells by magnetic field preconditioning
MV Kurian, L Hamilton, J Keeven, P Mehl, JM Mullins
Apoptosis 2012
An Apoptosis Signal-regulating Kinase 1 Inhibitor Reduces Cardiomyocyte Apoptosis and Infarct Size in a Rat Ischemia-reperfusion Model:
PZ Gerczuk, DG Breckenridge, JT Liles, GR Budas, JC Shryock, L Belardinelli, RA Kloner, W Dai
Journal of Cardiovascular Pharmacology 2012
Cardiac fibroblast death by ischemia/reperfusion is partially inhibited by IGF-1 through both PI3K/Akt and MEK–ERK pathways
R Vivar, C Humeres, M Varela, P Ayala, N Guzmán, I Olmedo, M Catalán, P Boza, C Muñoz, GD Araya
Experimental and Molecular Pathology 2012
Nitric oxide preserves XIAP and reduces hypoxia/reoxygenation-induced cardiomyocytes apoptosis via ERK1/2 activation
H Yuan, B Yan, HH Wang, S Hua, A Hu
Biochemical and Biophysical Research Communications 2012
Protective Role of Cardiac CFTR Activation Upon Early Reperfusion Against Myocardial Infarction
H Uramoto, T Okada, Y Okada
Cellular Physiology and Biochemistry 2012
Trichostatin A Ameliorates Myocardial Ischemia/Reperfusion Injury Through Inhibition of Endoplasmic Reticulum Stress-induced Apoptosis
L Yu, M Lu, P Wang, X Chen
Archives of Medical Research 2012
Reperfusion-triggered stress protein response in the myocardium is blocked by post-conditioning. Systems biology pathway analysis highlights the key role of the canonical aryl-hydrocarbon receptor pathway
G Vilahur, J Cubedo, L Casani, T Padro, M Sabate-Tenas, JJ Badimon, L Badimon
European Heart Journal 2012
Madecassoside, a triterpenoid saponin isolated from Centella asiatica herbs, protects endothelial cells against oxidative stress
D Bian, M Liu, Y Li, Y Xia, Z Gong, Y Dai
Journal of Biochemical and Molecular Toxicology 2012
Péptido similar al glucagón tipo 1 y supervivencia de la célula cardiaca
S Ravassa, A Zudaire, J Díez
Endocrinología y Nutrición 2012
Effects of xenon and isoflurane on apoptosis and inflammation in a porcine myocardial infarction model
S Sopka, C Mertens, AB Roehl, K Schiffl, R Rossaint, I Classen-Linke
Annals of Anatomy - Anatomischer Anzeiger 2012
Glucagon-like peptide 1 and cardiac cell survival
S Ravassa, A Zudaire, J Díez
Endocrinología y Nutrición (English Edition) 2012
Epoxyeicosatrienoic acids protect rat hearts against tumor necrosis factor-α-induced injury
G Zhao, J Wang, X Xu, Y Jing, L Tu, X Li, C Chen, K Cianflone, P Wang, RT Dackor, DC Zeldin, DW Wang
Journal of lipid research 2012
Redox-mediated programed death of myocardial cells after cardiac arrest and cardiopulmonary resuscitation
A Chalkias, T Xanthos
Redox Report 2012
Local Oxidative Stress Expansion through Endothelial Cells – A Key Role for Gap Junction Intercellular Communication
I Feine, I Pinkas, Y Salomon, A Scherz, M Ushio-Fukai
PloS one 2012
Strategic localization of heart mitochondrial NOS: a review of the evidence
T Zaobornyj, P Ghafourifar
American journal of physiology. Heart and circulatory physiology 2012
Safety and efficacy of intracoronary adenosine administration in patients with acute myocardial infarction undergoing primary percutaneous coronary intervention: a meta-analysis of randomized controlled trials
M Singh, T Shah, K Khosla, P Singh, J Molnar, S Khosla, R Arora
Therapeutic advances in cardiovascular disease 2012
Mitochondria and Their Role in Cardiovascular Disease
J Marín-García
2012
Atlas of Nuclear Cardiology
V Dilsizian, J Narula
2012
Management of Myocardial Reperfusion Injury
JC Kaski, DJ Hausenloy, BJ Gersh, DM Yellon
2012
The Ubiquitin Ligase MuRF1 Protects Against Cardiac Ischemia/Reperfusion Injury by Its Proteasome-Dependent Degradation of Phospho-c-Jun
HH Li, J Du, YN Fan, ML Zhang, DP Liu, L Li, P Lockyer, EY Kang, C Patterson, MS Willis
The American Journal of Pathology 2011
Role of various proteases in cardiac remodeling and progression of heart failure
AL Müller, NS Dhalla
Heart Failure Reviews 2011
Apnea stimulates the adaptive response to oxidative stress in elephant seal pups
JP Vázquez-Medina, T Zenteno-Savín, MS Tift, HJ Forman, DE Crocker, RM Ortiz
The Journal of experimental biology 2011
Cytoprotection by the modulation of mitochondrial electron transport chain: The emerging role of mitochondrial STAT3
K Szczepanek, Q Chen, AC Larner, EJ Lesnefsky
Mitochondrion 2011
High-molecular-weight polyethylene glycol protects cardiac myocytes from hypoxia- and reoxygenation-induced cell death and preserves ventricular function
R Malhotra, V Valuckaite, ML Staron, T Theccanat, KM D'Souza, JC Alverdy, SA Akhter
American journal of physiology. Heart and circulatory physiology 2011
Molecular MRI of Acute Necrosis With a Novel DNA-Binding Gadolinium Chelate: Kinetics of Cell Death and Clearance in Infarcted Myocardium
S Huang, HH Chen, H Yuan, G Dai, DT Schuhle, C Mekkaoui, S Ngoy, R Liao, P Caravan, L Josephson, DE Sosnovik
Circulation. Cardiovascular imaging 2011
Advances in Clinical Chemistry
M Mahler
Advances in Clinical Chemistry Volume 54 2011
Base des phénomènes d’ischémie reperfusion et de la protection myocardique
S Benhabbouche, CC da silva, M Abrial, R Ferrera
Annales Françaises d'Anesthésie et de Réanimation 2011
Protective effect of the apoptosis-sensing nanoparticle AnxCLIO-Cy5.5
HH Chen, Y Feng, M Zhang, W Chao, L Josephson, SY Shaw, DE Sosnovik
Nanomedicine: Nanotechnology, Biology and Medicine 2011
Nogo-A knockdown inhibits hypoxia/reoxygenation-induced activation of mitochondrial-dependent apoptosis in cardiomyocytes
JP Sarkey, M Chu, M McShane, E Bovo, YA Mou, AV Zima, PP de Tombe, GL Kartje, JL Martin
Journal of Molecular and Cellular Cardiology 2011
Protective effects of cynaroside against H2O2-induced apoptosis in H9c2 cardiomyoblasts
X Sun, G Sun, M Wang, J Xiao, X Sun
Journal of Cellular Biochemistry 2011
Levosimendan preserves the contractile responsiveness of hypoxic human myocardium via mitochondrial KATP channel and potential pERK 1/2 activation
PF Soeding, PJ Crack, CE Wright, JA Angus, CF Royse
European Journal of Pharmacology 2011
Luteolin improves contractile function and attenuates apoptosis following ischemia–reperfusion in adult rat cardiomyocytes
L Qi, H Pan, D Li, F Fang, D Chen, H Sun
European Journal of Pharmacology 2011
Toll-Like Receptor 4Stimulation Initiates an Inflammatory Response That Decreases Cardiomyocyte Contractility
O Avlas, R Fallach, A Shainberg, E Porat, E Hochhauser
Antioxidants & Redox Signaling 2011
Rutaecarpine prevents hypoxia–reoxygenation-induced myocardial cell apoptosis via inhibition of NADPH oxidases
MH Bao, W Dai, YJ Li, CP Hu
Canadian Journal of Physiology and Pharmacology 2011
Evaluation of adenosine preconditioning with 99mTc-His10-annexin V in a porcine model of myocardium ischemia and reperfusion injury: preliminary study
F Ye, W Fang, F Wang, ZC Hua, Z Wang, X Yang
Nuclear Medicine and Biology 2011
The clinical impact of circulating caspase-3 p17 level: a potential new biomarker for myocardial injury and cardiovascular disease
KP Singh, AS Jaffe, BT Liang
Future Cardiology 2011
Lethal myocardial reperfusion injury: A necessary evil?
B Ibanez, V Fuster, J Jiménez-Borreguero, JJ Badimon
International Journal of Cardiology 2011
Combined VEGF gene transfer and erythropoietin in ovine reperfused myocardial infarction
FD Olea, AD Lorenzi, C Cortés, L Cuniberti, L Fazzi, MP Flamenco, P Locatelli, PC Meckert, A Bercovich, R Laguens, A Crottogini
International Journal of Cardiology 2011
Role of p38 inhibition in cardiac ischemia/reperfusion injury
S Kumphune, S Chattipakorn, N Chattipakorn
European Journal of Clinical Pharmacology 2011
Anti-Apoptotic Effect of Hyperbaric Oxygen Preconditioning on a Rat Model of Myocardial Infarction
Q Sun, Q Sun, Y Liu, X Sun, H Tao
Journal of Surgical Research 2011
Anti-apoptotic protection afforded by cardioplegic celsior and histidine buffer solutions to hearts subjected to ischemia and ischemia/reperfusion
MG Alves, NG Machado, VA Sardão, RA Carvalho, PJ Oliveira
Journal of Cellular Biochemistry 2011
High-dose insulin in experimental myocardial infarction in rabbits: protection against effects of hyperglycaemia
VW Wong, M Mardini, NW Cheung, AS Mihailidou
Journal of Diabetes and its Complications 2011
In vivo gene delivery of XIAP protects against myocardial apoptosis and infarction following ischemia/reperfusion in conscious rabbits
SJ Kim, A Kuklov, GJ Crystal
Life Sciences 2011
TGF-β2 treatment enhances cytoprotective factors released from embryonic stem cells and inhibits apoptosis in infarcted myocardium
DK Singla, RD Singla, S Lamm, C Glass
American journal of physiology. Heart and circulatory physiology 2011
The combined transduction of copper, zinc-superoxide dismutase and catalase mediated by cell-penetrating peptide, PEP-1, to protect myocardium from ischemia-reperfusion injury
GQ Huang, JN Wang, JM Tang, L Zhang, F Zheng, JY Yang, LY Guo, X Kong, YZ Huang, Y Liu, SY Chen
Journal of Translational Medicine 2011
Type 10 adenylyl cyclase mediates mitochondrial Bax translocation and apoptosis of adult rat cardiomyocytes under simulated ischaemia/reperfusion
A Appukuttan, SA Kasseckert, M Micoogullari, JP Flacke, S Kumar, A Woste, Y Abdallah, L Pott, HP Reusch, Y Ladilov
Cardiovascular Research 2011
Heart Failure: A Companion to Braunwald's Heart Disease
A Diwan, GW Dorn
Heart Failure: A Companion to Braunwald's Heart Disease 2011
Molecular and cellular mechanisms involved in cardiac remodeling after acute myocardial infarction
G Vilahur, O Juan-Babot, E Peña, B Oñate, L Casaní, L Badimon
Journal of Molecular and Cellular Cardiology 2011
Sodium hydrosulfide improves the protective potential of the cardioplegic histidine buffer solution
MG Alves, AF Soares, RA Carvalho, PJ Oliveira
European Journal of Pharmacology 2011
High-molecular-weight polyethylene glycol protects cardiac myocytes from hypoxia- and reoxygenation-induced cell death and preserves ventricular function
R Malhotra, V Valuckaite, ML Staron, T Theccanat, KM D'Souza, JC Alverdy, SA Akhter
American journal of physiology. Heart and circulatory physiology 2011
TGF-β2 treatment enhances cytoprotective factors released from embryonic stem cells and inhibits apoptosis in infarcted myocardium
DK Singla, RD Singla, S Lamm, C Glass
American journal of physiology. Heart and circulatory physiology 2011
Blockade of Caspase-2 Activity Inhibits Ischemia/Reperfusion-Induced Mitochondrial Reactive Oxygen Burst and Cell Death in Cardiomyocytes
ZH Shao, KR Wojcik, Y Qin, CQ Li, TL Hoek, KJ Hamann
Journal of cell death 2011
Protective effect of intermedin on myocardial cell in a rat model of severe acute pancreatitis
X Du, Y Cao, P Xue, Z Lin, Z Zeng, Q Xia
Cellular & Molecular Biology Letters 2011
Signaling in the Heart
J Marín-García
2011
Molecular Defects in Cardiovascular Disease
NS Dhalla, M Nagano, B Ostadal
2011
Mechanical Stretch and Cytokines
A Kamkin, I Kiseleva
2011
Activation of calcium-sensing receptors is associated with apoptosis in a model of simulated cardiomyocytes ischemia/reperfusion
L Yan, T Zhu, T Sun, L Wang, S Pan, Z Tao, Z Yang, K Cao
Journal of Biomedical Research 2010
Cellular stress responses: cell survival and cell death
S Fulda, AM Gorman, O Hori, A Samali
International Journal of Cell Biology 2010
Protein Kinases as Drug Development Targets for Heart Disease Therapy
NS Dhalla, AL Müller
Pharmaceuticals (Basel, Switzerland) 2010
Netrin-1 prevents ischemia/reperfusion-induced myocardial infarction via a DCC/ERK1/2/eNOS s1177/NO/DCC feed-forward mechanism
J Zhang, H Cai
Journal of Molecular and Cellular Cardiology 2010
Pim-1 Kinase Protects Mitochondrial Integrity in Cardiomyocytes
GA Borillo, M Mason, P Quijada, M Völkers, C Cottage, M McGregor, S Din, K Fischer, N Gude, D Avitabile, S Barlow, R Alvarez, S Truffa, R Whittaker, MS Glassy, AB Gustafsson, S Miyamoto, CC Glembotski, RA Gottlieb, JH Brown, MA Sussman
Circulation research 2010
Cell Death in the Pathogenesis of Heart Disease: Mechanisms and Significance
RS Whelan, V Kaplinskiy, RN Kitsis
Annual Review of Physiology 2010
How to Mediate Cardioprotection in Ischemic Hearts—Accumulated Evidence of Basic Research Should Translate to Clinical Medicine
M Kitakaze
Cardiovascular Drugs and Therapy 2010
Sevoflurane postconditioning prevents activation of caspase 3 and 9 through antiapoptotic signaling after myocardial ischemia–reperfusion
Y Inamura, M Miyamae, S Sugioka, N Domae, J Kotani
Journal of Anesthesia 2010
Small-animal SPECT and SPECT/CT: application in cardiovascular research
R Golestani, C Wu, RA Tio, CJ Zeebregts, AD Petrov, FJ Beekman, RA Dierckx, HH Boersma, RH Slart
European Journal of Nuclear Medicine and Molecular Imaging 2010
Connexin 43 mimetic peptide Gap26 confers protection to intact heart against myocardial ischemia injury
G Hawat, M Benderdour, G Rousseau, G Baroudi
Pflügers Archiv - European Journal of Physiology 2010
Apoptosis in Cardiovascular Diseases: Mechanism and Clinical Implications
NH Kim, PM Kang
Korean Circulation Journal 2010
Imaging of apoptosis in the heart with nanoparticle technology
HH Chen, L Josephson, DE Sosnovik
Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology 2010
In Vivo Fluorometric Assessment of Cyclosporine on Mitochondrial Function During Myocardial Ischemia and Reperfusion
M Matsubara, M Ranji, BG Leshnower, M Noma, SJ Ratcliffe, B Chance, RC Gorman, JH 3rd
The Annals of Thoracic Surgery 2010
PAF exerts a direct apoptotic effect on the rat H9c2 cardiomyocytes in Ca2+-dependent manner
D Zhao, WF Chu, L Wu, J Li, QM Liu, YJ Lu, GF Qiao, ZG Wang, ZR Zhang, BF Yang
International Journal of Cardiology 2010
Attenuating Ischemia-Induced H9c2 Myoblasts Apoptosis by Therapeutic Hypothermia
CH Lin, WS Wu, MT Lin, WP Liu, RB Hsu, CP Chang
The American Journal of the Medical Sciences 2010
The Role of the Transcription Factor Nuclear Factor Kappa B in the Regulation of Cardiac Hypertrophy
D Sorriento, G Iaccarino, B Trimarco
High Blood Pressure & Cardiovascular Prevention 2010
Reduction of Myocardial Ischemia-Reperfusion Injury by Mechanical Tissue Resuscitation Using Sub-Atmospheric Pressure
LC Argenta, MJ Morykwas, JJ Mays, EA Thompson, JW Hammon, JE Jordan
Journal of Cardiac Surgery 2010
Apoptosis is not involved in the mechanism of myocardial dysfunction after resuscitation in a rat model of cardiac arrest and cardiopulmonary resuscitation
F Song, Y Shan, F Cappello, F Rappa, G Ristagno, T Yu, GL Volti, S Sun, MH Weil, W Tang
Critical Care Medicine 2010
The role of p53, bax, bcl2, and 8-OHdG in human acute myocardial infarction
RA Najar, SM Ghaderian, H Vakili, AS Panah, AR Farimani, G Rezaie, AB Harchegani
Central European Journal of Biology 2010
Indomethacin Reduces Cell Damage: Shedding New Light on Compartment Syndrome
A Manjoo, D Sanders, A Lawendy, M Gladwell, D Gray, N Parry, A Badhwar
Journal of Orthopaedic Trauma 2010
Antiapoptotic potential of herbal drugs in cardiovascular disorders: An overview
R Ahmad, S Javed, U Bhandari
Pharmaceutical Biology 2010
Cardioprotective properties of Crataegus oxycantha extract against ischemia-reperfusion injury
JK Swaminathan, M Khan, IK Mohan, K Selvendiran, SN Devaraj, BK Rivera, P Kuppusamy
Phytomedicine : international journal of phytotherapy and phytopharmacology 2010
Myocardium and microvessel endothelium apoptosis at day 7 following reperfused acute myocardial infarction
S Kang, Y Yang, Y Wu, Y Chen, L Li, Y Tian
Microvascular Research 2010
Cardioprotective activity of urocortin by preventing caspase-independent, non-apoptotic death in cultured neonatal rat cardiomyocytes exposed to ischemia
T Takatani-Nakase, K Takahashi
Biochemical and Biophysical Research Communications 2010
Curculigoside attenuates human umbilical vein endothelial cell injury induced by H2O2
YK Wang, YJ Hong, M Wei, Y Wu, ZQ Huang, RZ Chen, HZ Chen
Journal of Ethnopharmacology 2010
Activation of Bone Remodeling after Fatigue: Differential Response to Linear Microcracks and Diffuse Damage
BC Herman, L Cardoso, RJ Majeska, KJ Jepsen, MB Schaffler
Bone 2010
Vitamins & Hormones
KJ Hare, FK Knop
Vitamins & Hormones 2010
Biomarkers: In Medicine, Drug Discovery, and Environmental Health
AS McLean, SJ Huang
Biomarkers: In Medicine, Drug Discovery, and Environmental Health 2010
Sirolimus in Kidney Transplant Donors and Clinical and Histologic Improvement in Recipients: Rat Model
F Cicora, N Lausada, DN Vasquez, P Cicora, G Zalazar, P Gonzalez, G Palti, C Raimondi
Transplantation Proceedings 2010
Trimetazidine, Administered at the Onset of Reperfusion, Ameliorates Myocardial Dysfunction and Injury by Activation of p38 Mitogen-Activated Protein Kinase and Akt Signaling
M Khan, S Meduru, M Mostafa, S Khan, K Hideg, P Kuppusamy
The Journal of pharmacology and experimental therapeutics 2010
Herba Epimedii: Anti-Oxidative Properties and Its Medical Implications
SC Sze, Y Tong, TB Ng, CL Cheng, HP Cheung
Molecules (Basel, Switzerland) 2010
Cancer Nanotechnology
SR Grobmyer, BM Moudgil
Cancer Nanotechnology 2010
Studies on Cardiovascular Disorders
H Sauer, AM Shah, FR Laurindo
2010
New Solutions for the Heart
BK Podesser, DJ Chambers
2010
Pulmonary surfactant: an immunological perspective
ZC Chroneos, Z Sever-Chroneos, VL Shepherd
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2009
Involvement of GADD153 and cardiac ankyrin repeat protein in cardiac ischemia-reperfusion injury
MJ Lee, YK Kwak, KR You, BH Lee, DG Kim
Experimental and Molecular Medicine 2009
Apoptosis
P Erhardt, A Toth
Apoptosis 2009
Apoptosis
P Erhardt, A Toth
Apoptosis 2009
Near infrared light protects cardiomyocytes from hypoxia and reoxygenation injury by a nitric oxide dependent mechanism
R Zhang, Y Mio, PF Pratt, N Lohr, DC Warltier, HT Whelan, D Zhu, ER Jacobs, M Medhora, M Bienengraeber
Journal of Molecular and Cellular Cardiology 2009
Apoptosis predominates in nonmyocytes in heart failure
M Park, YT Shen, V Gaussin, GR Heyndrickx, J Bartunek, RR Resuello, FF Natividad, RN Kitsis, DE Vatner, SF Vatner
American journal of physiology. Heart and circulatory physiology 2009
FAK regulates cardiomyocyte survival following ischemia/reperfusion
ZS Hakim, LA DiMichele, M Rojas, D Meredith, CP Mack, JM Taylor
Journal of Molecular and Cellular Cardiology 2009
Role of apoptosis in cardiovascular disease
Y Lee, ÅB Gustafsson
Apoptosis 2009
Quantifying Acute Myocardial Injury Using Ratiometric Fluorometry
M Ranji, M Matsubara, BG Leshnower, RH Hinmon, DL Jaggard, B Chance, RC Gorman, JH Gorman
IEEE Transactions on Biomedical Engineering 2009
Prevention of ischemia/reperfusion-induced cardiac apoptosis and injury by melatonin is independent of glutathione peroxdiase 1
Z Chen, CC Chua, J Gao, KW Chua, YS Ho, RC Hamdy, BH Chua
Journal of Pineal Research 2009
Circulating p53 and cytochrome c levels in acute myocardial infarction patients
Y Dincer, S Himmetoglu, E Bozcali, VA Vural, T Akcay
Journal of Thrombosis and Thrombolysis 2009
Role of AIF in cardiac apoptosis in hypertrophic cardiomyocytes from Dahl salt-sensitive rats
S Choudhury, S Bae, SR Kumar, Q Ke, B Yalamarti, JH Choi, LA Kirshenbaum, PM Kang
Cardiovascular Research 2009
Bax distribution into mitochondrial detergent-resistant microdomains is related to ceramide and cholesterol content in postischemic hearts
E Martínez-Abundis, F Correa, N Pavón, C Zazueta
FEBS Journal 2009
Matrix metalloproteinase-2 and myocardial oxidative stress injury: beyond the matrix
AD Kandasamy, AK Chow, MA Ali, R Schulz
Cardiovascular Research 2009
Pathophysiological significance of apoptosis and its potential for treating heart diseases
G Takemura
Folia Pharmacologica Japonica 2009
4-Guanidino-n-butyl Syringate (Leonurine, SCM 198) Protects H9c2 Rat Ventricular Cells From Hypoxia-induced Apoptosis
X Liu, P Chen, L Pan, RD Silva, Y Zhu
Journal of Cardiovascular Pharmacology 2009
Post-ischemic Infusion of Atrial Natriuretic Peptide Attenuates Warm Ischemia–Reperfusion Injury in Rat Lung
A Aoyama, F Chen, T Fujinaga, A Sato, T Tsuruyama, J Zhang, T Shoji, H Sakai, T Nakamura, H Date, H Wada, T Bando
The Journal of Heart and Lung Transplantation 2009
Molecular imaging of cell death
MD Saint-Hubert, K Prinsen, L Mortelmans, A Verbruggen, FM Mottaghy
Methods 2009
Antioxidants in the prevention of myocardial ischemia/reperfusion injury
C Qin, S Yap, OL Woodman
Expert Review of Clinical Pharmacology 2009
Protective effect of electroacupuncture at the Neiguan point in a rabbit model of myocardial ischemia-reperfusion injury
H Zhang, L Liu, G Huang, L Zhou, W Wu, T Zhang, H Huang
Canadian Journal of Cardiology 2009
IL-10 attenuates TNF- -induced NF B pathway activation and cardiomyocyte apoptosis
S Dhingra, AK Sharma, RC Arora, J Slezak, PK Singal
Cardiovascular Research 2009
Induction of RISK by HMG-CoA reductase inhibition affords cardioprotection after myocardial infarction
G Vilahur, L Casaní, E Peña, X Duran, O Juan-Babot, L Badimon
Atherosclerosis 2009
Mitochondrial Involvement in Cardiac Apoptosis During Ischemia and Reperfusion: Can We Close the Box?
NG Machado, MG Alves, RA Carvalho, PJ Oliveira
Cardiovascular Toxicology 2009
Insulin inhibits myocardial ischemia-induced apoptosis and alleviates chronic adverse changes in post-ischemic cardiac structure and function
W Xing, W Yan, F Fu, Y Jin, L Ji, W Liu, L Wang, A Lv, Y Duan, J Zhang, H Zhang, F Gao
Apoptosis 2009
Anaesthesia and myocardial ischaemia/reperfusion injury
J Frassdorf, SD Hert, W Schlack
British Journal of Anaesthesia 2009
Apoptosis in Human Acute Myocardial Infarction: The Rationale for Clinical Trials of Apoptosis Inhibition in Acute Myocardial Infarction
SW Rabkin
Scholarly Research Exchange 2009
Cardioprotection: A radical view
C Penna, D Mancardi, R Rastaldo, P Pagliaro
Biochimica et Biophysica Acta (BBA) - Bioenergetics 2009
Myocyte apoptosis occurs early during the development of pressure-overload hypertrophy in infant myocardium
YH Choi, DB Cowan, AM Moran, SD Colan, C Stamm, K Takeuchi, I Friehs, PJ Nido, FX McGowan
The Journal of Thoracic and Cardiovascular Surgery 2009
Cellular mechanisms of cardioprotection by calorie restriction: state of the science and future perspectives
E Marzetti, SE Wohlgemuth, SD Anton, R Bernabei, CS Carter, C Leeuwenburgh
Clinics in Geriatric Medicine 2009
Myocardial Apoptosis and Infarction after Ischemia/Reperfusion Are Attenuated by κ-Opioid Receptor Agonist
F Rong, Z Peng, Y Ming-Xiang, QY Zhang, Y Zhao, SM Zhang, HT Guo, H Bi, YM Wang, C Liang, CH Gu, C Tao, Q Cui, SQ Yu, DH Yi, JM Pei
Archives of Medical Research 2009
Apelin protects heart against ischemia/reperfusion injury in rat
XJ Zeng, LK Zhang, HX Wang, LQ Lu, LQ Ma, CS Tang
Peptides 2009
Toll-like receptor signaling: a critical modulator of cell survival and ischemic injury in the heart
W Chao
American journal of physiology. Heart and circulatory physiology 2009
Apoptosis predominates in nonmyocytes in heart failure
M Park, YT Shen, V Gaussin, GR Heyndrickx, J Bartunek, RR Resuello, FF Natividad, RN Kitsis, DE Vatner, SF Vatner
American journal of physiology. Heart and circulatory physiology 2009
Combined therapy with cardioprotective cytokine administration and antiapoptotic gene transfer in postinfarction heart failure
H Okada, G Takemura, K Kosai, A Tsujimoto, M Esaki, T Takahashi, S Nagano, H Kanamori, S Miyata, Y Li, T Ohno, R Maruyama, A Ogino, L Li, M Nakagawa, K Nagashima, T Fujiwara, H Fujiwara, S Minatoguchi
American journal of physiology. Heart and circulatory physiology 2009
Cardioprotective effects of benazepril, an angiotensin-converting enzyme inhibitor, in an ischaemia-reperfusion model of myocardial infarction in rats
KC Sahoo, S Arora, S Goyal, K Kishore, R Ray, TC Nag, DS Arya
Journal of Renin-Angiotensin-Aldosterone System 2009
Molecular MRI of Cardiomyocyte Apoptosis With Simultaneous Delayed-Enhancement MRI Distinguishes Apoptotic and Necrotic Myocytes In Vivo: Potential for Midmyocardial Salvage in Acute Ischemia
DE Sosnovik, E Garanger, E Aikawa, M Nahrendorf, JL Figuiredo, G Dai, F Reynolds, A Rosenzweig, R Weissleder, L Josephson
Circulation. Cardiovascular imaging 2009
Klinische Kardiologie
E Erdmann
2009
Essentials of Apoptosis
Z Dong, XM Yin
2009
Apoptosome
F Cecconi, M D'Amelio
2009
Forkhead Transcription Factors
K Maiese
2009
Protective effect of electroacupuncture at the Neiguan point in a rabbit model of myocardial ischemia-reperfusion injury.
Zhang H, Liu L, Huang G, Zhou L, Wu W, Zhang T, Huang H
The Canadian journal of cardiology 2009
A cell penetrating heme oxygenase protein protects heart graft against ischemia/reperfusion injury
J Ma, CK Lau, A Obed, A Dada, A Doenecke, ST Fan, HJ Schlitt, TY Tsui
Gene Therapy 2008
Ultrastructural definition of apoptosis in heart failure
E Arbustini, A Brega, J Narula
Heart Failure Reviews 2008
Programmed cell death in cardiac myocytes: strategies to maximize post-ischemic salvage
K Mani
Heart Failure Reviews 2008
Sphingomyelinases: their regulation and roles in cardiovascular pathophysiology
C Pavoine, F Pecker
Cardiovascular Research 2008
The paradigm of postconditioning to protect the heart
C Penna, D Mancardi, S Raimondo, S Geuna, P Pagliaro
Journal of Cellular and Molecular Medicine 2008
The rationale for cardiomyocyte resuscitation in myocardial salvage
GW Dorn, A Diwan
Journal of Molecular Medicine 2008
Toll-like receptor signaling: a critical modulator of cell survival and ischemic injury in the heart
W Chao
American journal of physiology. Heart and circulatory physiology 2008
Simultaneous Administration of Insulin-Like Growth Factor-1 and Darbepoetin Alfa Protects the Rat Myocardium Against Myocardial Infarction and Enhances Angiogenesis
M Boucher, S Pesant, YH Lei, N Nanton, P Most, AD Eckhart, WJ Koch, E Gao
Clinical and Translational Science 2008
Cardioprotective Effects of Erythropoietin in Rats Subjected to Ischemia–Reperfusion Injury: Assessment of Infarct Size with 99m Tc-Annexin V
T Doue, K Ohtsuki, K Ogawa, M Ueda, A Azuma, H Saji, HW Strauss, H Matsubara
Journal of Nuclear Medicine 2008
Biphasic onset of splenic apoptosis following hemorrhagic shock: critical implications for Bax, Bcl-2, and Mcl-1 proteins
A Hostmann, K Jasse, G Schulze-Tanzil, Y Robinson, A Oberholzer, W Ertel, SK Tschoeke
Critical Care 2008
Fundamental and Clinical Cardiology Series
PD Stein
Cardiovascular Disease in the Elderly 2008
Ginsenoside Rb1 Preconditioning Protects Against Myocardial Infarction After Regional Ischemia and Reperfusion by Activation of Phosphatidylinositol-3-kinase Signal Transduction
Z Wang, M Li, W Wu, H Tan, D Geng
Cardiovascular Drugs and Therapy 2008
Role of oxidative stress in hypertrophied myoblasts stimulated by isoproterenol
K Itoh, M Minakawa, Y Ono, T Tsushima, K Fukui, I Fukuda
General Thoracic and Cardiovascular Surgery 2008
Over-expression of a modified bifunctional apoptosis regulator protects against cardiac injury and doxorubicin-induced cardiotoxicity in transgenic mice
CC Chua, J Gao, YS Ho, X Xu, IC Kuo, KY Chua, H Wang, RC Hamdy, JC Reed, BH Chua
Cardiovascular Research 2008
Cardiomyocyte-targeted siRNA delivery by prostaglandin E2-Fas siRNA polyplexes formulated with reducible poly(amido amine) for preventing cardiomyocyte apoptosis
SH Kim, JH Jeong, M Ou, JW Yockman, SW Kim, DA Bull
Biomaterials 2008
Blockade of the Fas/Fas ligand interaction suppresses hepatocyte apoptosis in ischemia-reperfusion rat liver
H Nakajima, N Mizuta, I Fujiwara, K Sakaguchi, H Ogata, J Magae, H Yagita, T Koji
Apoptosis 2008
Mitochondria: A mirror into cellular dysfunction in heart disease
MY White, AV Edwards, SJ Cordwell, JE van Eyk
PROTEOMICS – CLINICAL APPLICATIONS 2008
Direct Stenting after Thrombus Removal before Primary Angioplasty in Acute Myocardial Infarction
P Silva-Orrego, R Bigi, P Colombo, FD Marco, JA Oreglia, S Klugmann, D Gregori
Journal of Interventional Cardiology 2008
Antiapoptosis and Mitochondrial Effect of Pioglitazone Preconditioning in the Ischemic/reperfused Heart of Rat
J Li, MJ Lang, XB Mao, L Tian, YB Feng
Cardiovascular Drugs and Therapy 2008
Glycogen Synthase Kinase 3 Inhibition Protects the Heart From Acute Ischemia-Reperfusion Injury Via Inhibition of Inflammation and Apoptosis
HK Gao, Z Yin, N Zhou, XY Feng, F Gao, HC Wang
Journal of Cardiovascular Pharmacology 2008
INHIBITION OF p53 BY PIFITHRIN-α REDUCES MYOCYTE APOPTOSIS AND LEUKOCYTE TRANSMIGRATION IN AGED RAT HEARTS FOLLOWING 24 HOURS OF REPERFUSION
P Liu, B Xu, TA Cavalieri, CE Hock
Shock 2008
gp130-mediated pathway and heart failure
K Yamauchi-Takihara
Future Cardiology 2008
Ischemia/reperfusion-induced necrosis and apoptosis in the cells isolated from rat skeletal muscle
WZ Wang, XH Fang, LL Stephenson, KT Khiabani, WA Zamboni
Journal of Orthopaedic Research 2008
Cardiomyocyte death and renewal in the normal and diseased heart
LM Buja, D Vela
Cardiovascular Pathology 2008
Valoración de la viabilidad miocárdica mediante gated-SPECT de perfusión miocárdica
FX Albert-Bertran, J Castell-Conesa
Revista Española de Cardiología Suplementos 2008
Regulation of cell survival by Na + /H + exchanger-1
JR Schelling, BG Jawdeh
American journal of physiology. Renal physiology 2008
Review Paper: Pathophysiology of Myocardial Reperfusion Injury: The Role of Genetically Engineered Mouse Models
A Ramachandran, S Jha, DJ Lefer
Veterinary pathology 2008
Anti-Apoptotic Effect of Magnolol in Myocardial Ischemia and Reperfusion Injury Requires Extracellular Signal-Regulated Kinase1/2 Pathways in Rat In Vivo
YC Jin, KJ Kim, YM Kim, YM Ha, HJ Kim, UJ Yun, KH Bae, YS Kim, SS Kang, HG Seo, JH Lee, KC Chang
Experimental biology and medicine (Maywood, N.J.) 2008
Impact of Ischemia and Reperfusion Times on Myocardial Infarct Size in Mice In Vivo
A Redel, V Jazbutyte, TM Smul, M Lange, T Eckle, H Eltzschig, N Roewer, F Kehl
Experimental biology and medicine (Maywood, N.J.) 2008
Atherosclerosis and Oxidant Stress
JL Holtzman
2008
Inhibition of Ischemic Cardiomyocyte Apoptosis Through Targeted Ablation of Bnip3 Restrains Post-infarction Remodeling
Abhinav Diwan, Maike Krenz, Faisal M. Syed, Janaka Wansapura, Xiaoping Ren, Andrew G. Koesters, Hairong Li, Lorrie A. Kirshenbaum, Harvey S. Hahn, Jeffrey Robbins, W. Keith Jones, and Gerald W. Dorn II
Journal of Clinical Investigation 2007
Impaired perfusion after myocardial infarction is due to reperfusion-induced δPKC-mediated myocardial damage
F Ikeno, K Inagaki, M Rezaee, D Mochly-Rosen
Cardiovascular Research 2007
Reperfusion injury salvage kinase signalling: taking a RISK for cardioprotection
DJ Hausenloy, DM Yellon
Heart Failure Reviews 2007
"AKT"ing lessons for stem cells: regulation of cardiac myocyte and progenitor cell proliferation
M Sussman
Trends in Cardiovascular Medicine 2007
Preconditioning and postconditioning: United at reperfusion
DJ Hausenloy, DM Yellon
Pharmacology & Therapeutics 2007
Caspase-9-dependent pathway to murine germ cell apoptosis: mediation by oxidative stress, BAX, and caspase 2
JJ Lysiak, S Zheng, R Woodson, TT Turner
Cell and Tissue Research 2007
Noninvasive imaging of apoptosis in cardiovascular disease
EC Korngold, FA Jaffer, R Weissleder, DE Sosnovik
Heart Failure Reviews 2007
Periods of systemic partial hypoxia induces apoptosis and inflammation in rat skeletal muscle
N Aravindan, S Aravindan, K Shanmugasundaram, AD Shaw
Molecular and Cellular Biochemistry 2007
Shenfu injection suppresses apoptosis by regulation of Bcl-2 and caspase-3 during hypoxia/reoxygenation in neonatal rat cardiomyocytes in vitro
Y Wang, C Wang, B Zhang, Z Zhang
Molecular Biology Reports 2007
Heart Failure
HH Chen
Journal of the American College of Cardiology 2007
INHIBITION OF MYOCARDIAL APOPTOSIS BY POSTCONDITIONING IS ASSOCIATED WITH ATTENUATION OF OXIDATIVE STRESS-MEDIATED NUCLEAR FACTOR-κB TRANSLOCATION AND TNFα RELEASE
H Kin, NP Wang, J Mykytenko, J Reeves, J Deneve, R Jiang, AJ Zatta, RA Guyton, J Vinten-Johansen, ZQ Zhao
Shock 2007
Recombinant human-activated protein C inhibits cardiomyocyte apoptosis in a rat model of myocardial ischemia???reperfusion
B Pirat, H Muderrisoglu, MT Unal, H Ozdemir, A Yildirir, M Yucel, S Turkoglu
Coronary Artery Disease 2007
Sirolimus Improves Early Microcirculation, but Impairs Regeneration After Pancreatic Ischemia-Reperfusion Injury
F Serr, H Lauer, B Armann, S Ludwig, J Thiery, M Fiedler, U Ceglarek, A Tannapfel, D Uhlmann, J Hauss, H Witzigmann
American Journal of Transplantation 2007
ARC contributes to the inhibitory effect of preconditioning on cardiomyocyte apoptosis
YZ Li, XH Liu, XM Zhu, LR Cai
Apoptosis 2007
Oxidative Stress and Cardiac Repair/Remodeling Following Infarction
Y Sun
The American Journal of the Medical Sciences 2007
99mTc-Annexin-V Uptake in a Rat Model of Variable Ischemic Severity and Reperfusion Time
J Taki, T Higuchi, A Kawashima, JF Tait, A Muramori, I Matsunari, K Nakajima, JL Vanderheyden, HW Strauss
Circulation Journal 2007
Induction of Heme Oxygenase-1 Improves the Survival of Pancreas Grafts by Prevention of Pancreatitis After Transplantation
T Becker, AM Vilsendorf, T Terbish, J Klempnauer, A Jörns
Transplantation 2007
Myocardial uptake of 99mTc-annexin-V and 111In-antimyosin-antibodies after ischemia-reperfusion in rats
L Sarda-Mantel, F Hervatin, JB Michel, L Louedec, G Martet, F Rouzet, R Lebtahi, P Merlet, BA Khaw, D Guludec
European Journal of Nuclear Medicine and Molecular Imaging 2007
Ischemic preconditioning: protection against myocardial necrosis and apoptosis
EK Iliodromitis, A Lazou, DT Kremastinos
Vascular Health and Risk Management 2007
Trimetazidine inhibits cardiomyocyte apoptosis in a rabbit model of ischemia-reperfusion
Y Ruixing, L Wenwu, R Al-Ghazali
Translational Research 2007
Surgery for Myocardial Salvage in Acute Myocardial Infarction and Acute Coronary Syndromes
GM Comas, BC Esrig, MC Oz
Heart Failure Clinics 2007
Cell suicide and caspases
SK Rupinder, AK Gurpreet, S Manjeet
Vascular Pharmacology 2007
Post-Genomic Cardiology
J Marín-García, MJ Goldenthal, GW Moe
Post-Genomic Cardiology 2007
Cellular death linked to irreversible stress in the sarcoplasmic reticulum: The effect of inhibiting Ca2+–ATPase or protein glycosylation in the myocardiac cell model H9c2
F Soler, A Lax, F Fernández-Belda
Archives of Biochemistry and Biophysics 2007
Relevance of apoptosis in influencing recovery of hibernating myocardium
A Angelini, G Maiolino, GL Canna, C Ceconi, F Calabrese, E Pettenazzo, M Valente, O Alfieri, G Thiene, R Ferrari
European Journal of Heart Failure 2007
The cardioprotective effect of mesenchymal stem cells is mediated by IGF-I and VEGF
S Sadat, S Gehmert, YH Song, Y Yen, X Bai, S Gaiser, H Klein, E Alt
Biochemical and Biophysical Research Communications 2007
Inhibition of Thrombin During Reperfusion Improves Immediate Postischemic Myocardial Function and Modulates Apoptosis in a Porcine Model of Cardiopulmonary Bypass
M Jormalainen, AE Vento, H Lukkarinen, P Kääpä, V Kytö, J Lauronen, T Paavonen, R Suojaranta-Ylinen, J Petäjä
Journal of Cardiothoracic and Vascular Anesthesia 2007
Gender specific effect of progesterone on myocardial ischemia/reperfusion injury in rats
VV Dhote, R Balaraman
Life Sciences 2007
The Effects of Propofol on Cardiac Function After 4 Hours of Cold Cardioplegia and Reperfusion
SU Choi, HW Lee, HJ Lim, SM Yoon, SH Chang
Journal of Cardiothoracic and Vascular Anesthesia 2007
Role of monocyte chemoattractant protein-1 in myocardial infarction
H Morimoto, M Takahashi
International journal of biomedical science : IJBS 2007
Overexpression of IAP-2 attenuates apoptosis and protects against myocardial ischemia/reperfusion injury in transgenic mice
CC Chua, J Gao, YS Ho, Y Xiong, X Xu, Z Chen, RC Hamdy, BH Chua
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research 2007
Activation of apoptotic processes during transition from hypertrophy to heart failure in guinea pigs
AK Sharma, S Dhingra, N Khaper, PK Singal
American journal of physiology. Heart and circulatory physiology 2007
Modulation of electron transport protects cardiac mitochondria and decreases myocardial injury during ischemia and reperfusion
Q Chen, AK Camara, DF Stowe, CL Hoppel, EJ Lesnefsky
American journal of physiology. Cell physiology 2007
Past and present course of cardioprotection against ischemia- reperfusion injury
DA Liem, HM Honda, J Zhang, D Woo, P Ping
Journal of applied physiology 2007
Abolition of reperfusion-induced arrhythmias in hearts from thiamine-deficient rats
FA Oliveira, S Guatimosim, CH Castro, DT Galan, S Lauton-Santos, AM Ribeiro, AP Almeida, JS Cruz
American journal of physiology. Heart and circulatory physiology 2007
Bcl-2 family members and apoptosis, taken to heart
ÅB Gustafsson, RA Gottlieb
American journal of physiology. Cell physiology 2007
Induction of cardioplegic arrest immediately activates the myocardial apoptosis signal pathway
UM Fischer, CS Cox, GA Laine, U Mehlhorn, W Bloch, SJ Allen
American journal of physiology. Heart and circulatory physiology 2007
Mitochondria
SW Schaffer, MS Suleiman
2007
Therapeutic Neovascularization–Quo Vadis?
E Deindl, C Kupatt
2007
Apoptosis, Cell Signaling, and Human Diseases
R Srivastava
2007
Necrosis Avidity of 99m Tc(CO) 3 -Labeled Pamoic acid Derivatives: Synthesis and Preliminary Biological Evaluation in Animal Models of Necrosis
H Fonge, SK Chitneni, J Lixin, K Vunckx, K Prinsen, J Nuyts, L Mortelmans, G Bormans, Y Ni, A Verbruggen
Bioconjugate Chemistry 2007
Myocardial uptake of 99mTc-annexin-V and 111In-antimyosin-antibodies after ischemia-reperfusion in rats
L Sarda-Mantel, F Hervatin, JB Michel, L Louedec, G Martet, F Rouzet, R Lebtahi, P Merlet, BA Khaw, DL Guludec
European Journal of Nuclear Medicine and Molecular Imaging 2007
Targeted deletion of Puma attenuates cardiomyocyte death and improves cardiac function during ischemia-reperfusion
A Toth, JR Jeffers, P Nickson, JY Min, JP Morgan, GP Zambetti, P Erhardt
American journal of physiology. Heart and circulatory physiology 2006
Role of Adenosine as Adjunctive Therapy in Acute Myocardial Infarction
MB Forman, GW Stone, EK Jackson
Cardiovascular Drug Reviews 2006
Potential biomarkers for ischemic heart damage identified in mitochondrial proteins by comparative proteomics
N Kim, Y Lee, H Kim, H Joo, JB Youm, WS Park, M Warda, DV Cuong, J Han
PROTEOMICS 2006
Fibrin(ogen) and its fragments in the pathophysiology and treatment of myocardial infarction
K Zacharowski, P Zacharowski, S Reingruber, P Petzelbauer
Journal of Molecular Medicine 2006
Mechanisms of apoptosis after ischemia and reperfusion: Role of the renin-angiotensin system
P Kossmehl, E Kurth, S Faramarzi, B Habighorst, M Shakibaei, M Wehland, R Kreutz, M Infanger, AH Danser, J Grosse, M Paul, D Grimm
Apoptosis 2006
Molecular cloning, sequence, function and structural basis of human heart 150 kDa oxygen-regulated protein, an ER chaperone
S Takeuchi
The Protein Journal 2006
Role of interleukin-4 in atherosclerosis
YW Lee, AA Hirani
Archives of Pharmacal Research 2006
Effects of Circuit Miniaturization in Reducing Inflammatory Response to Infant Cardiopulmonary Bypass by Elimination of Allogeneic Blood Products
E Hickey, T Karamlou, J You, RM Ungerleider
The Annals of Thoracic Surgery 2006
Thrombus Aspiration Before Primary Angioplasty Improves Myocardial Reperfusion in Acute Myocardial Infarction
P Silva-Orrego, P Colombo, R Bigi, D Gregori, A Delgado, P Salvade, J Oreglia, P Orrico, A Biase, G Piccalò, I Bossi, S Klugmann
Journal of the American College of Cardiology 2006
Ischemic but not mechanical preconditioning attenuates ischemia/reperfusion induced myocardial apoptosis in anaesthetized rabbits: The role of Bcl-2 family proteins and ERK1/2
A Lazou, EK Iliodromitis, D Cieslak, K Voskarides, S Mousikos, E Bofilis, DT Kremastinos
Apoptosis 2006
Cardiac Molecular Signaling After Burn Trauma
DL Carlson, JW Horton
Journal of Burn Care & Research 2006
Isoflurane Produces Sustained Cardiac Protection after Ischemia???Reperfusion Injury in Mice
YM Tsutsumi, HH Patel, NC Lai, T Takahashi, BP Head, DM Roth
Anesthesiology 2006
Corydalis yanhusuo rhizoma extract reduces infarct size and improves heart function during myocardial ischemia/reperfusion by inhibiting apoptosis in rats
H Ling, L Wu, L Li
Phytotherapy Research 2006
Molecular Mechanisms in Heart Failure
D Hilfiker-Kleiner, U Landmesser, H Drexler
Journal of the American College of Cardiology 2006
DY-9760e, a Novel Calmodulin Inhibitor, Exhibits Cardioprotective Effects in the Ischemic Heart
K Fukunaga, F Han, N Shioda, S Moriguchi, J Kasahara, Y Shirasaki
Cardiovascular Drug Reviews 2006
Fluorescence spectroscopy and imaging of myocardial apoptosis
M Ranji, S Kanemoto, M Matsubara, MA Grosso, JH Gorman, RC Gorman, DL Jaggard, B Chance
Journal of Biomedical Optics 2006
Upregulation of mitochondrial respiratory complex IV by estrogen receptor-β is critical for inhibiting mitochondrial apoptotic signaling and restoring cardiac functions following trauma–hemorrhage
YC Hsieh, HP Yu, T Suzuki, MA Choudhry, MG Schwacha, KI Bland, IH Chaudry
Journal of Molecular and Cellular Cardiology 2006
“How Do Cardiomyocytes Die?” Apoptosis and Autophagic Cell Death in Cardiac Myocytes
S Kunapuli, S Rosanio, ER Schwarz
Journal of Cardiac Failure 2006
A novel SOD-mimetic permeability transition inhibitor agent protects ischemic heart by inhibiting both apoptotic and necrotic cell death
Z Bognar, T Kalai, A Palfi, K Hanto, B Bognar, L Mark, Z Szabo, A Tapodi, B Radnai, Z Sarszegi, A Szanto, F Gallyas, K Hideg, B Sumegi, G Varbiro
Free radical biology & medicine 2006
In stent restenosis: bane of the stent era
AK Mitra, DK Agrawal
Journal of clinical pathology 2006
Cell death in the cardiovascular system
M Clarke, M Bennett, T Littlewood
Heart (British Cardiac Society) 2006
Bax translocates to mitochondria of heart cells during simulated ischaemia: involvement of AMP-activated and p38 mitogen-activated protein kinases
M Capano, M Crompton
Biochemical Journal 2006
Matrix metalloproteinase-2 contributes to tumor necrosis factor alpha induced apoptosis in cultured rat cardiac myocytes
J Shen, D O’Brien, Y Xu
Biochemical and Biophysical Research Communications 2006
Myocardial Preconditioning Against Ischemia-Induced Apoptosis and Necrosis in Man
HA Vohra, M Galiñanes
Journal of Surgical Research 2006
Dendroaspis natriuretic peptide protects the post-ischemic myocardial injury
KC Ha, CS Piao, HJ Chae, HR Kim, SW Chae
Regulatory Peptides 2006
Preconditioning prevents loss in mitochondrial function and release of cytochrome c during prolonged cardiac ischemia/reperfusion
KC Lundberg, LI Szweda
Archives of Biochemistry and Biophysics 2006
Critical role of PI3-kinase/Akt activation in the PARP inhibitor induced heart function recovery during ischemia–reperfusion
K Kovacs, A Toth, P Deres, T Kalai, K Hideg, F Gallyas, B Sumegi
Biochemical Pharmacology 2006
The role of ATP sensitive K+ channels and of nitric oxide synthase on myocardial ischemia/reperfusion-induced apoptosis
S Gok, S Vatansever, K Vural, C Sekuri, A İzanlı, A Tezcan, S Cilaker
Acta Histochemica 2006
Morphological aspects of apoptosis in heart diseases
Genzou Takemura, Hisayoshi Fujiwara
Journal of Cellular and Molecular Medicine 2006
Pretreatment with probucol attenuates cardiomyocyte apoptosis in a rabbit model of ischemia/reperfusion
Y Ruixing, R AlGhazali, L Wenwu, W Jinzhen
Scandinavian Journal of Clinical & Laboratory Investigation 2006
Involvement of polyamines in apoptosis of cardiac myoblasts in a model of simulated ischemia
B Tantini, E Fiumana, S Cetrullo, C Pignatti, F Bonavita, LM Shantz, E Giordano, C Muscari, F Flamigni, C Guarnieri, C Stefanelli, CM Caldarera
Journal of Molecular and Cellular Cardiology 2006
Myocardial apoptosis associated with the expression of proinflammatory cytokines during the course of myocardial infarction
Y Akasaka, N Morimoto, Y Ishikawa, K Fujita, K Ito, M Kimura-Matsumoto, S Ishiguro, H Morita, Y Kobayashi, T Ishii
Modern Pathology 2006
Myocyte apoptosis during acute myocardial infarction in rats is related to early sarcolemmal translocation of annexin A5 in border zone
V Monceau, Y Belikova, G Kratassiouk, E Robidel, F Russo-Marie, D Charlemagne
American journal of physiology. Heart and circulatory physiology 2006
C-phycocyanin protects against ischemia-reperfusion injury of heart through involvement of p38 MAPK and ERK signaling
M Khan, S Varadharaj, LP Ganesan, JC Shobha, MU Naidu, NL Parinandi, S Tridandapani, VK Kutala, P Kuppusamy
American journal of physiology. Heart and circulatory physiology 2006
cGMP-dependent Protein Kinase Type I Inhibits TAB1-p38 Mitogen-activated Protein Kinase Apoptosis Signaling in Cardiac Myocytes
B Fiedler, R Feil, F Hofmann, C Willenbockel, H Drexler, A Smolenski, SM Lohmann, KC Wollert
The Journal of biological chemistry 2006
Green Tea Protects Cytoskeleton from Oxidative Injury in Cardiomyocytes
E Pagnotta, N Calonghi, S Hrelia, L Masotti, P Biagi, C Angeloni
Journal of Agricultural and Food Chemistry 2006
Protective effect of agmatine on a reperfusion model after transient cerebral ischemia: Temporal evolution on perfusion MR imaging and histopathologic findings
D J Kim, D I Kim, S K Lee, S H Suh, Y J Lee, J Kim, T S Chung, J E Lee
American Journal of Neuroradiology 2006
Serum deoxyribonuclease I activity can be used as a sensitive marker for detection of transient myocardial ischaemia induced by percutaneous coronary intervention
K Arakawa, Y Kawai, T Kumamoto, N Morikawa, M Yoshida, H Tada, R Kawaguchi, K Taniguchi, I Miyamori, Y Kominato, K Kishi, T Yasuda
European Heart Journal 2005
Apoptosis and oncosis in acute coronary syndromes: Assessment and implications
BI Jugdutt, HA Idikio
Molecular and Cellular Biochemistry 2005
Biochemical dysfunction in heart mitochondria exposed to ischaemia and reperfusion
G Solaini, DA Harris
Biochemical Journal 2005
H11 has dose-dependent and dual hypertrophic and proapoptotic functions in cardiac myocytes
M Hase, C Depre, SF Vatner, J Sadoshima
Biochemical Journal 2005
Gene transfer of the pancaspase inhibitor P35 reduces myocardial infarct size and improves cardiac function
L Bott-Flügel, HJ Weig, M Knödler, C Städele, A Moretti, KL Laugwitz, M Seyfarth
Journal of Molecular Medicine 2005
Death begets failure in the heart
RS Foo, K Mani, RN Kitsis
Journal of Clinical Investigation 2005
A nonerythropoietic derivative of erythropoietin protects the myocardium from ischemia-reperfusion injury
F Fiordaliso, S Chimenti, L Staszewsky, A Bai, E Carlo, I Cuccovillo, M Doni, M Mengozzi, R Tonelli, P Ghezzi, T Coleman, M Brines, A Cerami, R Latini
Proceedings of the National Academy of Sciences 2005
The Reperfusion Injury Salvage Kinase Pathway: A Common Target for Both Ischemic Preconditioning and Postconditioning
DJ Hausenloy, A Tsang, DM Yellon
Trends in Cardiovascular Medicine 2005
Interleukin-6/soluble interleukin-6 receptor complex reduces infarct size via inhibiting myocardial apoptosis
K Matsushita, S Iwanaga, T Oda, K Kimura, M Shimada, M Sano, A Umezawa, J Hata, S Ogawa
Laboratory Investigation 2005
Tumor necrosis factor-??-induced caspase activation mediates endotoxin-related cardiac dysfunction*
DL Carlson, MS Willis, DJ White, JW Horton, BP Giroir
Critical Care Medicine 2005
Don't lose heart - therapeutic value of apoptosis prevention in the treatment of cardiovascular disease
JL Reeve, AM Duffy, T O'Brien, A Samali
Journal of Cellular and Molecular Medicine 2005
Effect of L-carnitine on cardiomyocyte apoptosis and cardiac function in patients undergoing heart valve replacement operation
X Daokang, S Zongquan, X Jiahong, D Nianguo, D Xinling, C Xinzhong
Journal of Huazhong University of Science and Technology [Medical Sciences] 2005
Immunohistochemical expression of activated caspase-3 in human myocardial infarction
N Zidar, Z Dolenc-Stražar, J Jeruc, D Štajer
Virchows Archiv 2005
Hypoxia-reoxygenation-induced apoptosis in cultured neonatal rat cardiomyocyets and the protective effect of prostaglandin E1
X Ma, R Fu, G Feng, Z Wang, S Ma, S Weng
Clinical and Experimental Pharmacology and Physiology 2005
Cardiomyocyte Apoptosis After Antegrade and Retrograde Cardioplegia
T Vähäsilta, A Saraste, V Kytö, M Malmberg, J Kiss, E Kentala, M Kallajoki, T Savunen
The Annals of Thoracic Surgery 2005
Apoptosis: a basic biological phenomenon with wide-ranging implications in human disease
B Fadeel, S Orrenius
Journal of Internal Medicine 2005
Caspase Inhibition Improves Ischemia-Reperfusion Injury After Lung Transplantation
SM Quadri, L Segall, M Perrot, B Han, V Edwards, N Jones, TK Waddell, M Liu, S Keshavjee
American Journal of Transplantation 2005
Isoflurane Protects against Myocardial Infarction during Early Reperfusion by Activation of Phosphatidylinositol-3-Kinase Signal Transduction: Evidence for Anesthetic-induced Postconditioning in Rabbits
PC Chiari, MW Bienengraeber, PS Pagel, JG Krolikowski, JR Kersten, DC Warltier
Anesthesiology 2005
ClC-3-independent Sensitivity of Apoptosis to Cl<sup>&ndash;</sup> Channel Blockers in Mouse Cardiomyocytes
N Takahashi, X Wang, S Tanabe, H Uramoto, K Jishage, S Uchida, S Sasaki, Y Okada
Cellular Physiology and Biochemistry 2005
Sustained Cardioprotection Afforded by A2A Adenosine Receptor Stimulation After 72 Hours of Myocardial Reperfusion
M Boucher, BP Wann, S Kaloustian, R Mass??, Schampaert, R Cardinal, G Rousseau
Journal of Cardiovascular Pharmacology 2005
Ischemic Preconditioning Can Overcome the Effect of Moderate to Severe Cold Ischemia on Concordant Mouse Xeno–Heart Transplants
DJ Lukes, A Lundgren, U Skogsberg, A Karlsson-Parra, B Soussi, M Olausson
Transplantation Proceedings 2005
Pathomechanisms of cartilage destruction by mechanical injury
B Kurz, AK Lemke, J Fay, T Pufe, AJ Grodzinsky, M Schünke
Annals of Anatomy - Anatomischer Anzeiger 2005
Protective effects of icariin on human umbilical vein endothelial cell injury induced by H2O2 in vitro
YK Wang, ZQ Huang
Pharmacological Research 2005
Role of Smac/DIABLO in hydrogen peroxide-induced apoptosis in C2C12 myogenic cells
B Jiang, W Xiao, Y Shi, M Liu, X Xiao
Free radical biology & medicine 2005
Imaging Techniques in Nuclear Cardiology for the Assessment of Myocardial Viability
RH Slart, JJ Bax, DJ Veldhuisen, EE Wall, RA Dierckx, PL Jager
The International Journal of Cardiovascular Imaging 2005
Effect of the degree of ischaemic injury and reoxygenation time on the type of myocardial cell death in man: role of caspases
HA Vohra, M Galiñanes
BMC Physiology 2005
Myocardial protection in reperfusion with postconditioning
J Vinten-Johansen, ZQ Zhao, R Jiang, AJ Zatta
Expert Review of Cardiovascular Therapy 2005
Oxidative stress in organ preservation: a multifaceted approach to cardioplegia
SK Nelson, S Bose, M Rizeq, JM McCord
Biomedicine & Pharmacotherapy 2005
Pulmonary Apoptosis After Supraceliac Aorta Clamping in a Rat Model1
O Collange, F Tamion, N Rives, C Thuillez, V Richard, B Dureuil, D Plissonnier
Journal of Surgical Research 2005
Protective effects of silybin on human umbilical vein endothelial cell injury induced by H2O2 in vitro
YK Wang, Y Hong, ZQ Huang
Vascular Pharmacology 2005
JNK mediates hepatic ischemia reperfusion injury
T Uehara, B Bennett, ST Sakata, Y Satoh, GK Bilter, JK Westwick, DA Brenner
Journal of Hepatology 2005
Isoflurane-induced myocardial preconditioning is dependent on phosphatidylinositol-3-kinase/Akt signalling
J Raphael, J Rivo, Y Gozal
British Journal of Anaesthesia 2005
Cell Death During HIV Infection
M Smith-Raska, M Lenardo, K Sakai
Cell Death During HIV Infection: gp120 2005
Animal models for the study of myocardial protection against ischemia
S Philipp, MV Cohen, JM Downey
Drug Discovery Today: Disease Models 2005
Reducing risk in infant cardiopulmonary bypass: The use of a miniaturized circuit and a crystalloid prime improves cardiopulmonary function and increases cerebral blood flow
T Karamlou, E Hickey, CC Silliman, I Shen, RM Ungerleider
Seminars in Thoracic and Cardiovascular Surgery Pediatric Cardiac Surgery Annual 2005
Dysfunction of the adrenal cortex: an exploration of molecular mechanisms
PJ Hornsby
Journal of Organ Dysfunction 2005
Lipopolysaccharide Improves Cardiomyocyte Survival and Function after Serum Deprivation
W Chao, Y Shen, X Zhu, H Zhao, M Novikov, U Schmidt, A Rosenzweig
The Journal of biological chemistry 2005
Involvement of GADD153 and Cardiac Ankyrin Repeat Protein in Hypoxia-induced Apoptosis of H9c2 Cells
XJ Han, JK Chae, MJ Lee, KR You, BH Lee, DG Kim
The Journal of biological chemistry 2005
Phosphodiesterase-5 Inhibitor Sildenafil Preconditions Adult Cardiac Myocytes against Necrosis and Apoptosis: ESSENTIAL ROLE OF NITRIC OXIDE SIGNALING
A Das, L Xi, RC Kukreja
The Journal of biological chemistry 2005
Ischemic preconditioning modulates the expression of several genes, leading to the overproduction of IL-1Ra, iNOS, and Bcl-2 in a human model of liver ischemia-reperfusion
A Barrier, N Olaya, F Chiappini, F Roser, O Scatton, C Artus, B Franc, S Dudoit, A Flahault, B Debuire, D Azoulay, A Lemoine
The FASEB Journal 2005
Induction of cell death in rat small intestine by ischemia reperfusion: differential roles of Fas/Fas ligand and Bcl-2/Bax systems depending upon cell types
S An, Y Hishikawa, T Koji
Histochemistry and Cell Biology 2005
Mitochondria and the Heart
J Marín-García
2005
Chloride Channel Inhibition Prevents ROSdependentApoptosis Induced by Ischemia-Reperfusion in Mouse Cardiomyocytes
X Wang, N Takahashi, H Uramoto, Y Okada
Cellular Physiology and Biochemistry 2005
Apoptosis in Health and Disease: Clinical and Therapeutic Aspects
M Holcik, EC LaCasse, AE MacKenzie, RG Korneluk
2005
99mTc-annexin V and 111In-antimyosin antibody uptake in experimental myocardial infarction in rats
L Sarda-Mantel, JB Michel, F Rouzet, G Martet, L Louedec, JL Vanderheyden, F Hervatin, O Raguin, JM Vrigneaud, BA Khaw, DL Guludec
European Journal of Nuclear Medicine and Molecular Imaging 2005
Imaging Techniques in Nuclear Cardiology for the Assessment of Myocardial Viability
RH Slart, JJ Bax, DJ van Veldhuisen, EE van der Wall, RA Dierckx, PL Jager
The International Journal of Cardiovascular Imaging 2005
Cardiomyocyte-specific Bcl-2 overexpression attenuates ischemia-reperfusion injury, immune response during acute rejection, and graft coronary artery disease
M Tanaka, S Nakae, RD Terry, GK Mokhtari, F Gunawan, LB Balsam, H Kaneda, T Kofidis, PS Tsao, RC Robbins
Blood 2004
Heme oxygenase‐1‐derived carbon monoxide protects hearts from transplant‐associated ischemia reperfusion injury
Y Akamatsu, M Haga, S Tyagi, K Yamashita, AV GraçaSouza, R Ollinger, E Czismadia, GA May, E Ifedigbo, LE Otterbein, FH Bach, MP Soares
The FASEB Journal 2004
Reflecting on 80 years of excellence
U Savla
Journal of Clinical Investigation 2004
Heart mitochondria signaling pathways: appraisal of an emerging field
J Marn-Garca, MJ Goldenthal
Journal of Molecular Medicine 2004
Nitric oxide and promotion of cardiac myocyte apoptosis
P Andréka, T Tran, KA Webster, NH Bishopric
Molecular and Cellular Biochemistry 2004
Functional and clinical repercussions of myocyte apoptosis in the multifaceted damage by ischemia/reperfusion injury: old and new concepts after 10 years of contributions
TM Scarabelli, RA Gottlieb
Cell Death and Differentiation 2004
Multiple deficiencies in antioxidant enzymes in mice result in a compound increase in sensitivity to oxidative stress
HV Remmen, W Qi, M Sabia, G Freeman, L Estlack, H Yang, ZM Guo, TT Huang, R Strong, S Lee, CJ Epstein, A Richardson
Free radical biology & medicine 2004
Inhibition of c-Jun N-terminal kinase decreases cardiomyocyte apoptosis and infarct size after myocardial ischemia and reperfusion in anaesthetized rats
C Ferrandi, R Ballerio, P Gaillard, C Giachetti, S Carboni, PA Vitte, JP Gotteland, R Cirillo
British Journal of Pharmacology 2004
Attenuation of ischemia and/or reperfusion injury during myocardial infarction using mild hypothermia in rats: An immunohistochemical study of Bcl-2, Bax, Bak and TUNEL
PP Babu, G Suzuki, Y Ono, Y Yoshida
Pathology International 2004
Ischemia/reperfusion injury: A review in relation to free tissue transfers
M Siemionow, E Arslan
Microsurgery 2004
Improved profile of bad phosphorylation and caspase 3 activation after blood versus crystalloid cardioplegia
J Feng, C Bianchi, J Li, FW Sellke
The Annals of Thoracic Surgery 2004
Inhaled nitric oxide attenuates apoptosis in ischemia-reperfusion injury of the rabbit lung
H Yamashita, S Akamine, Y Sumida, M Inoue, T Sawada, T Nagayasu, T Oka
The Annals of Thoracic Surgery 2004
Transient and reversible deoxyribonucleic acid damage in human left ventricle under controlled ischemia and reperfusion
GG Corbucci, C Perrino, G Donato, A Ricchi, B Lettieri, G Troncone, C Indolfi, M Chiariello, EV Avvedimento
Journal of the American College of Cardiology 2004
Mitochondrial Permeability Transition in Cardiomyocyte Apoptosis during Acute Graft Rejection
O Raisky, L Gomez, L Chalabreysse, O Gateau-Roesch, J Loufouat, F Thivolet-Bejui, J Ninet, M Ovize
American Journal of Transplantation 2004
Identification of Caspase-Independent PKC.EPSILON.-JNK/p38 MAPK Signaling Module in Response to Metabolic Inhibition in H9c2 Cells
YS Jung, YS Jung, MY Kim, E Kim
The Japanese Journal of Physiology 2004
Assessment of apoptosis in epidermal lamellar cells in clinically normal horses and those with laminitis
RR Faleiros, AM Stokes, SC Eades, DY Kim, DB Paulsen, RM Moore
American Journal of Veterinary Research 2004
Role of apoptosis in remodeling after myocardial infarction
G Takemura, H Fujiwara
Pharmacology & Therapeutics 2004
A potentially critical role of phospholipases in central nervous system ischemic, traumatic, and neurodegenerative disorders
JW Phillis, MH O'Regan
Brain Research Reviews 2004
Nitric oxide: a signaling molecule against mitochondrial permeability transition- and pH-dependent cell death after reperfusion
JS Kim, S Ohshima, P Pediaditakis, JJ Lemasters
Free radical biology & medicine 2004
Apoptosis: Pathophysiology and therapeutic implications for the cardiac surgeon
A Khoynezhad, Z Jalali, AJ Tortolani
The Annals of Thoracic Surgery 2004
Reduction of ischemia and reperfusion-induced myocardial damage by cytochrome P450 inhibitors
DJ Granville, B Tashakkor, C Takeuchi, AB Gustafsson, C Huang, MR Sayen, P Wentworth, M Yeager, RA Gottlieb
Proceedings of the National Academy of Sciences 2004
Apoptosis after reperfused myocardial infarction: Role of angiotensin II
BI Jugdutt
Experimental and clinical cardiology 2004
Regulation of cardiac myocyte apoptosis by the GATA-4 transcription factor
YJ Suzuki, T Evans
Life Sciences 2004
Reduction of infarct size and preservation of endothelial function by multidose intravenous adenosine during extended reperfusion
JM Budde, CD Morris, DA Velez, S Muraki, NP Wang, RA Guyton, ZQ Zhao
Journal of Surgical Research 2004
Nutritional supplementation with mixed essential amino acids enhances myocyte survival, preserving mitochondrial functional capacity during ischemia-reperfusion injury
TM Scarabelli, E Pasini, A Stephanou, C Chen-Scarabelli, L Saravolatz, RA Knight, DS Latchman, JM Gardin
The American Journal of Cardiology 2004
Synthesis and evaluation of anti-apoptotic activity of L-carnitine cyclic analogues and amino acid derivatives
R Fringuelli, MP Navarro, L Milanese, S Bruscoli, F Schiaffella, C Riccardi, CD Simone
Il Farmaco 2004
Initiation of mitochondrial-mediated apoptosis during cardiac reperfusion
KC Lundberg, LI Szweda
Archives of Biochemistry and Biophysics 2004
Local delivery of soluble TNF-alpha receptor 1 gene reduces infarct size following ischemia/reperfusion injury in rats
M Sugano, T Hata, K Tsuchida, N Suematsu, JI Oyama, S Satoh, N Makino
Molecular and Cellular Biochemistry 2004
Overexpression of mitogen-activated protein kinase kinase 6 in the heart improves functional recovery from ischemia in vitro and protects against myocardial infarction in vivo
JJ Martindale, JA Wall, DM Martinez-Longoria, P Aryal, HA Rockman, Y Guo, R Bolli, CC Glembotski
The Journal of biological chemistry 2004
Wasting of the left ventricle in patients with cardiac cachexia: a cardiovascular magnetic resonance study
VG Florea, J Moon, DJ Pennell, W Doehner, AJ Coats, SD Anker
International Journal of Cardiology 2004
Taurine prevents the ischemia-induced apoptosis in cultured neonatal rat cardiomyocytes through Akt/caspase-9 pathway
T Takatani, K Takahashi, Y Uozumi, T Matsuda, T Ito, SW Schaffer, Y Fujio, J Azuma
Biochemical and Biophysical Research Communications 2004
Cell death in cartilage
K Kühn, DD D’Lima, S Hashimoto, M Lotz
Osteoarthritis and Cartilage 2004
Post-Ischemic Cardioprotection by A2A Adenosine Receptors: Dependent of Phosphatidylinositol 3-Kinase Pathway:
M Boucher, S Pesant, S Falcao, C Montigny, É Schampaert, R Cardinal, G Rousseau
Journal of Cardiovascular Pharmacology 2004
Minoxidil Attenuates Ischemia-Induced Apoptosis in Cultured Neonatal Rat Cardiomyocytes:
T Takatani, K Takahashi, C Jin, T Matsuda, X Cheng, T Ito, J Azuma
Journal of Cardiovascular Pharmacology 2004
Apoptosis Repressor with Caspase Recruitment Domain Protects against Cell Death by Interfering with Bax Activation
ÅB Gustafsson, JG Tsai, SE Logue, MT Crow, RA Gottlieb
The Journal of biological chemistry 2004
Increased cell death in osteopontin-deficient cardiac fibroblasts occurs by a caspase-3-independent pathway
R Zohar, B Zhu, P Liu, J Sodek, CA McCulloch
American journal of physiology. Heart and circulatory physiology 2004
Na + /Ca 2+ exchanger plays a key role in inducing apoptosis after hypoxia in cultured guinea pig ventricular myocytes
BN Eigel, H Gursahani, RW Hadley
American journal of physiology. Heart and circulatory physiology 2004
Cardiac myocyte apoptosis provokes adverse cardiac remodeling in transgenic mice with targeted TNF overexpression
D Engel, R Peshock, RC Armstong, N Sivasubramanian, DL Mann
American journal of physiology. Heart and circulatory physiology 2004
Ceramide in the antiapoptotic effect of ischemic preconditioning
L Argaud, AF Prigent, L Chalabreysse, J Loufouat, M Lagarde, M Ovize
American journal of physiology. Heart and circulatory physiology 2004
Attenuation of fatty acid-induced apoptosis by low-dose alcohol in neonatal rat cardiomyocytes
GC Sparagna, CE Jones, DL Hickson-Bick
American journal of physiology. Heart and circulatory physiology 2004
Serum Troponins as Biomarkers of Drug-Induced Cardiac Toxicity
KB Wallace, E Hausner, E Herman, GD Holt, JT Macgregor, AL Metz, E Murphy, IY Rosenblum, FD Sistare, MJ York
Toxicologic pathology 2004
Taurine inhibits apoptosis by preventing formation of the Apaf-1/caspase-9 apoptosome
T Takatani, K Takahashi, Y Uozumi, E Shikata, Y Yamamoto, T Ito, T Matsuda, SW Schaffer, Y Fujio, J Azuma
American journal of physiology. Cell physiology 2004
Differential contribution of necrosis and apoptosis in myocardial ischemia-reperfusion injury
JD McCully, H Wakiyama, YJ Hsieh, M Jones, S Levitsky
American journal of physiology. Heart and circulatory physiology 2004
Apoptosis versus necrosis in acute pancreatitis
M Bhatia
AJP Gastrointestinal and Liver Physiology 2004
Ischemic preconditioning and morphine attenuate myocardial apoptosis and infarction after ischemia-reperfusion in rabbits: role of δ-opioid receptor
S Okubo, Y Tanabe, K Takeda, M Kitayama, S Kanemitsu, RC Kukreja, N Takekoshi
American journal of physiology. Heart and circulatory physiology 2004
The Role of Oxygen-Free Radical in the Apoptosis of Enterocytes in Scalded Rats After Delayed Resuscitation:
C Zhang, ZY Sheng, S Hu, JC Gao, JY Li, S Yu, Y Liu
The Journal of trauma 2004
IGF and Nutrition in Health and Disease
MS Houston, JM Holly, EL Feldman
2004
Protein Kinase C Mediates Cerebral Reperfusion Injury In Vivo
R Bright
The Journal of neuroscience : the official journal of the Society for Neuroscience 2004
A unique pathway of cardiac myocyte death caused by hypoxia–acidosis
RM Graham, DP Frazier, JW Thompson, S Haliko, H Li, BJ Wasserlauf, MG Spiga, NH Bishopric, KA Webster
The Journal of experimental biology 2004
Apoptotic adaptations from exercise training in skeletal and cardiac muscles
PM Siu, RW Bryner, JK Martyn, SE Alway
The FASEB Journal 2004
Activation of Mst1 causes dilated cardiomyopathy by stimulating apoptosis without compensatory ventricular myocyte hypertrophy
Shimako Yamamoto, Guiping Yang, Daniela Zablocki, Jing Liu, Chull Hong, Song-Jung Kim, Sandra Soler, Mari Odashima, Jill Thaisz, Ghassan Yehia, Carlos A Molina, Atsuko Yatani, Dorothy E Vatner, Stephen F Vatner, and Junichi Sadoshima
Journal of Clinical Investigation 2003
LOX-1 pathway affects the extent of myocardial ischemia-reperfusion injury
K Kataoka, K Hasegawa, T Sawamura, M Fujita, T Yanazume, E Iwai-Kanai, T Kawamura, T Hirai, T Kita, R Nohara
Biochemical and Biophysical Research Communications 2003
Mitochondrial defects and heterogeneous cytochrome c release after cardiac cold ischemia and reperfusion
AV Kuznetsov, S Schneeberger, R Seiler, G Brandacher, W Mark, W Steurer, V Saks, Y Usson, R Margreiter, E Gnaiger
American journal of physiology. Heart and circulatory physiology 2003
Cytoprotective and Antiapoptotic Effects of IL-13 in Hepatic Cold Ischemia/Reperfusion Injury Are Heme Oxygenase-1 Dependent
B Ke, XD Shen, CR Lassman, F Gao, RW Busuttil, JW Kupiec-Weglinski
American Journal of Transplantation 2003
Attenuation of increased myocardial ischaemia-reperfusion injury conferred by hypercholesterolaemia through pharmacological inhibition of the caspase-1 cascade
TD Wang, WJ Chen, TJ Mau, JW Lin, WW Lin, YT Lee
British Journal of Pharmacology 2003
Apoptosis versus oncotic necrosis in hepatic ischemia/reperfusion injury
H Jaeschke, JJ Lemasters
Gastroenterology 2003
Targeting ischemic cardiac dysfunction through gene transfer
T Matsui, A Rosenzweig
Current Atherosclerosis Reports 2003
Growth Factor Signaling for Cardioprotection Against Oxidative Stress-Induced Apoptosis
YJ Suzuki
Antioxidants & Redox Signaling 2003
The basic biology of apoptosis and its implications for cardiac function and viability
G Valen
The Annals of Thoracic Surgery 2003
Cardiomyocyte apoptosis and ischemic preconditioning in open heart operations
ZK Wu, J Laurikka, A Saraste, V Kytö, EJ Pehkonen, T Savunen, MR Tarkka
The Annals of Thoracic Surgery 2003
Differential Activation of Protein Kinase C between Ischemic and Pharmacological Preconditioning in the Rabbit Heart
S Okubo, Y Tanabe, N Fujioka, K Takeda, N Takekoshi
The Japanese Journal of Physiology 2003
Effects of ACE Inhibition on Myocardial Apoptosis in an Ischemia–Reperfusion Rat Heart Model
M Kobara, T Tatsumi, D Kambayashi, A Mano, S Yamanaka, J Shiraishi, N Keira, S Matoba, J Asayama, S Fushiki, M Nakagawa
Journal of Cardiovascular Pharmacology 2003
Expression of lectin-like oxidized low-density lipoprotein receptors during ischemia-reperfusion and its role in determination of apoptosis and left ventricular dysfunction
D Li, V Williams, L Liu, H Chen, T Sawamura, F Romeo, JL Mehta
Journal of the American College of Cardiology 2003
Insulin therapy as an adjunct toreperfusion after acute coronary ischemia
MN Sack, DM Yellon
Journal of the American College of Cardiology 2003
Increased myocardial apoptosis in patients with unfavorable left ventricular remodeling and early symptomatic post-infarction heart failure
A Abbate, GG Biondi-Zoccai, R Bussani, A Dobrina, D Camilot, F Feroce, R Rossiello, F Baldi, F Silvestri, LM Biasucci, A Baldi
Journal of the American College of Cardiology 2003
Myocyte apoptosis: programming ventricular remodeling**Editorials published in the Journal of the American College of Cardiology reflect the views of the authors and do not necessarily represent the views of JACC or the American College of Cardiology
K Mani, RN Kitsis
Journal of the American College of Cardiology 2003
Rapid new bone tissue remodeling during distraction osteogenesis is associated with apoptosis
G Li, GR Dickson, DR Marsh, H Simpson
Journal of Orthopaedic Research 2003
Inhibitors of swelling-activated chloride channels increase infarct size and apoptosis in rabbit myocardium
R Souktani, B Ghaleh, R Tissier, AA de Tassigny, K Aouam, P Bedossa, D Charlemagne, J Samuel, P Henry, A Berdeaux
Fundamental and Clinical Pharmacology 2003
Protective effect ofMangifera indica L. extract (Vimang�) on the injury associated with hepatic ischaemia reperfusion
GM S�nchez, MA H., A Giuliani, AJ Sell�s, NP Rodr�guez, OS Fern�ndez, L Re
Phytotherapy Research 2003
Enhanced Expression of the Apoptosis Inducing Ligand TRAIL in Mononuclear Cells After Myocardial Infarction
H Nakajima, N Yanase, K Oshima, A Sasame, T Hara, S Fukazawa, R Takata, K Hata, K Mukai, A Yamashina, J Mizuguchi
Japanese Heart Journal 2003
Intermittent hypoxia attenuates ischemia/reperfusion induced apoptosis in cardiac myocytes via regulating Bcl-2/Bax expression
JW DONG, HF ZHU, WZ ZHU, HL DING, TM MA, ZN ZHOU
Cell Research 2003
Adrenomedullin Infusion during Ischemia/Reperfusion Attenuates Left Ventricular Remodeling and Myocardial Fibrosis in Rats
H OKUMURA, N NAGAYA, K KANGAWA
Hypertension Research 2003
Nitric oxide and oxygen radicals induced apoptosis via bcl-2 and p53 pathway in hypoxia-reoxygenated cardiomyocytes
J Shen, X Qiu, B Jiang, D Zhang, W Xin, PC Fung, B Zhao
Science in China Series C: Life Sciences 2003
Apoptosis in heart: basic mechanisms and implications in cardiovascular diseases
PM Kang, S Izumo
Trends in Molecular Medicine 2003
Apoptosis in the myocardium: much is still expected
SR Umansky, LD Tomei
Expert Opinion on Therapeutic Targets 2003
Detection of stunned myocardium in post-reperfusion cases of acute myocardial infarction
R Tanaka, T Nakamura, H Kumamoto, M Miura, K Hirabayashi, N Okamoto, T Zaima, K Fujita
Annals of Nuclear Medicine 2003
Antiapoptotic Effect and Inhibition of Ischemia/Reperfusion-Induced Myocardial Injury in Metallothionein-Overexpressing Transgenic Mice
YJ Kang, Y Li, X Sun, X Sun
The American Journal of Pathology 2003
Recombinant human erythropoietin protects the myocardium from ischemia-reperfusion injury and promotes beneficial remodeling
L Calvillo, R Latini, J Kajstura, A Leri, P Anversa, P Ghezzi, M Salio, A Cerami, M Brines
Proceedings of the National Academy of Sciences 2003
Role of mitogen-activated protein kinase in cardiac hypertrophy and heart failure
W Zhang, V Elimban, MS Nijjar, SK Gupta, NS Dhalla
Experimental and clinical cardiology 2003
Osteogenic protein-1 reduces intercellular adhesion molecule-1 messenger RNA expression, infarct size and TUNEL-positive cardiomyocytes in ischemia/reperfusion rat hearts
J Hayashi, S Kusachi, T Murakami, T Miyoshi, K Nakamura, K Koten, H Ogawa, S Hirohata, Y Ninomiya, Y Shiratori
Experimental and clinical cardiology 2003
Tempero-spatial dissociation between the expression of Fas and apoptosis after coronary occlusion
QZ Feng, TD Li, LX Wei, X Qiao, J Yi, L Wang, TS Yang
Molecular pathology : MP 2003
The administration of α-melanocyte-stimulating hormone protects the ischemic/reperfused myocardium
M Vecsernyes, B Juhasz, P Der, R Kocsan, P Feher, I Bacskay, P Kovacs, A Tosaki
European Journal of Pharmacology 2003
Early onset of rejection in concordant hamster xeno hearts display signs of necrosis, but not apoptosis, correlating to the phosphocreatine concentration
DJ Lukes, Å Tivesten, J Wilton, A Lundgren, O Rakotonirainy, C Kjellström, J Isgaard, A Karlsson-Parra, B Soussi, M Olausson
Transplant Immunology 2003
Genetic editing of dysfunctional myocardium
RJ Hajjar, F Huq, T Matsui, A Rosenzweig
Medical Clinics of North America 2003
Mitochondrial permeability transition and cytochrome c release in ischemia-reperfusion injury of the rat liver
A Hirakawa, N Takeyama, T Nakatani, T Tanaka
Journal of Surgical Research 2003
Mitochondrial function: the heart of myocardial preservation
EO McFalls, D Liem, K Schoonderwoerd, J Lamers, W Sluiter, D Duncker
Journal of Laboratory and Clinical Medicine 2003
Opposing roles of δ and εPKC in cardiac ischemia and reperfusion: targeting the apoptotic machinery
CL Murriel, D Mochly-Rosen
Archives of Biochemistry and Biophysics 2003
Cardiac ischemia/reperfusion, aging, and redox-dependent alterations in mitochondrial function
HA Sadek, AC Nulton-Persson, PA Szweda, LI Szweda
Archives of Biochemistry and Biophysics 2003
Atrial natriuretic peptide preconditioning protects against hepatic preservation injury by attenuating necrotic and apoptotic cell death
T Gerwig, H Meiβner, M Bilzer, AK Kiemer, H Arnholdt, AM Vollmar, AL Gerbes
Journal of Hepatology 2003
H9c2 cardiac myoblasts undergo apoptosis in a model of ischemia consisting of serum deprivation and hypoxia: inhibition by PMA
F Bonavita, C Stefanelli, E Giordano, M Columbaro, A Facchini, F Bonafè, CM Caldarera, C Guarnieri
FEBS Letters 2003
Mitochondria in apoptosis of ischemic heart
V Borutaite, GC Brown
FEBS Letters 2003
Left ventricular wall stress as a direct correlate of cardiomyocyte apoptosis in patients with severe dilated cardiomyopathy
PD Napoli, AA Taccardi, A Grilli, M Felaco, A Balbone, D Angelucci, S Gallina, AM Calafiore, RD Caterina, A Barsotti
American Heart Journal 2003
Induction of apoptosis and ubiquitin hydrolase gene expression by human serum factors in the early phase of acute myocardial infarction
R Hasegawa, K Kita, R Hasegawa, K Fusejima, S Fukuzawa, C Wano, S Watanabe, H Saisho, Y Masuda, F Nomura, N Suzuki
The Journal of laboratory and clinical medicine 2003
Ischemia and reperfusion injury
MJ Wilhelm, J Pratschke, I Laskowski, NL Tilney
Transplantation Reviews 2003
Preconditioning with cardioplegia is more effective in reducing apoptosis than is preconditioning with ischemia in the human myocardium
HA Vohra, AG Fowler, M Galiñanes
Annals of the New York Academy of Sciences 2003
Blocking the development of postischemic cardiomyopathy with viral gene transfer of the apoptosis repressor with caspase recruitment domain
S Chatterjee, LT Bish, V Jayasankar, AS Stewart, YJ Woo, MT Crow, TJ Gardner, HL Sweeney
The Journal of Thoracic and Cardiovascular Surgery 2003
Pharmacologic inhibition of intracellular caspases after myocardial infarction attenuates left ventricular remodeling: a potentially novel pathway
WM Yarbrough, R Mukherjee, GP Escobar, JA Sample, JE McLean, KB Dowdy, JW Hendrick, WC Gibson, AE Hardin, JT Mingoia, PC White, A Stiko, RC Armstrong, FA Crawford, FG Spinale
The Journal of Thoracic and Cardiovascular Surgery 2003
Continuous Tepid Blood Cardioplegia Can Preserve Coronary Endothelium and Ameliorate the Occurrence of Cardiomyocyte Apoptosis
CH Yeh, YC Wang, YC Wu, JJ Chu, PJ Lin
Chest 2003
Left ventricular function and cardiovascular events following adjuvant therapy with adenosine in acute myocardial infarction treated with thrombolysis: Results of the ATTenuation by Adenosine of Cardiac Complications (ATTACC) study
M Quintana, P Hjemdahl, A Sollevi, T Kahan, M Edner, N Rehnqvist, E Swahn, AC Kjerr, P Näsman
European Journal of Clinical Pharmacology 2003
Ischemia-Reperfusion of the Murine Testis Stimulates the Expression of Proinflammatory Cytokines and Activation of c-jun N-Terminal Kinase in a Pathway to E-Selectin Expression1
JJ Lysiak, QA Nguyen, JL Kirby, TT Turner
Biology of reproduction 2003
High glucose promotes mesangial cell apoptosis by oxidant-dependent mechanism
BP Kang, S Frencher, V Reddy, A Kessler, A Malhotra, LG Meggs
American journal of physiology. Renal physiology 2003
Clinical implications of apoptosis in hypertensive heart disease
MA Fortuño, A González, S Ravassa, B López, J Dı́ez
American journal of physiology. Heart and circulatory physiology 2003
Preconditioning the Myocardium: From Cellular Physiology to Clinical Cardiology
DM Yellon, JM Downey
Physiological reviews 2003
Fas pathway is a critical mediator of cardiac myocyte death and MI during ischemia-reperfusion in vivo
P Lee, M Sata, DJ Lefer, SM Factor, K Walsh, RN Kitsis
American journal of physiology. Heart and circulatory physiology 2003
A novel method to determine specificity and sensitivity of the TUNEL reaction in the quantitation of apoptosis
KJ Kelly, RM Sandoval, KW Dunn, BA Molitoris, PC Dagher
American journal of physiology. Cell physiology 2003
Hibernation, Stunning, and Preconditioning: Historical Perspective, Current Concepts, Clinical Applications, and Future Implications
E Cosar, CJ O'Connor
Seminars in cardiothoracic and vascular anesthesia 2003
Effect of Chronic Hypoxia on Inducible Nitric Oxide Synthase Expression in Rat Myocardial Tissue
A Grilli, MA de Lutiis, A Patruno, L Speranza, A Cataldi, L Centurione, AA Taccardi, PD Napoli, RD Caterina, R Barbacane, P Conti, M Felaco
Experimental biology and medicine (Maywood, N.J.) 2003
Dissociation of Cytochrome c from the Inner Mitochondrial Membrane during Cardiac Ischemia
LW Czerski, PA Szweda, LI Szweda
The Journal of biological chemistry 2003
Liver death and regeneration in paracetamol toxicity
AH McGregor, LJ More, KJ Simpson, DJ Harrison
Human & Experimental Toxicology 2003
Polyphenolic Flavonoids Differ in Their Antiapoptotic Efficacy in Hydrogen Peroxide–Treated Human Vascular Endothelial Cells
YJ Choi, JS Kang, JH Park, YJ Lee, JS Choi, YH Kang
The Journal of nutrition 2003
Myocardial Ischemia and Preconditioning
NS Dhalla, N Takeda, M Singh, A Lukas
2003
Signal Transduction and Cardiac Hypertrophy
NS Dhalla, LV Hryshko, E Kardami, PK Singal
2003
Cardiac Remodeling and Failure
PK Singal, IM Dixon, LA Kirshenbaum, NS Dhalla
2003
Mechanism of cell death of rat cardiac fibroblasts induced by serum depletion
Monika Leicht, Grit Marx, Doris Karbach, Michael Gekle, Thomas Köhler, Heinz-Gerd Zimmer
Molecular and Cellular Biochemistry 2003
Mechanisms of Apoptosis in the Heart
ÅB Gustafsson, RA Gottlieb
Journal of Clinical Immunology 2003
Reperfusion, not simulated ischemia, initiates intrinsic apoptosis injury in chick cardiomyocytes
TL Hoek, Y Qin, K Wojcik, CQ Li, ZH Shao, T Anderson, LB Becker, KJ Hamann
American journal of physiology. Heart and circulatory physiology 2003
The cardioprotective effects of Na + /H + exchange inhibition and mitochondrial K ATP channel activation are additive in the isolated rat heart
XH Xiao, DG Allen
Pflügers Archiv - European Journal of Physiology 2003
The opening of mitochondrial KATP channels blocks cardiocyte apoptosis: mechanism of preconditioning
Huiping Liu, Xiangdong Zhu, Zuohui Shao, Zhenhai Yao
American journal of physiology. Heart and circulatory physiology 2002
In vivo gene transfer of soluble TNF-alpha receptor 1 alleviates myocardial infarction
M Sugano, M Koyanagi, K Tsuchida, T Hata, N Makino
The FASEB Journal 2002
Lecithinized superoxide dismutase reduces cold ischemia-induced chronic allograft dysfunction
K Nakagawa, DD Koo, DR Davies, DW Gray, AJ Mclaren, KI Welsh, PJ Morris, SV Fuggle
Kidney International 2002
Increased cardiomyocyte apoptosis following ischemia and reperfusion in diet-induced hypercholesterolemia: Relation to Bcl-2 and bax proteins and caspase-3 activity
TD Wang, WJ Chen, SS Su, SC Lo, WW Lin, YT Lee
Lipids 2002
Glucocorticoids reduce ischemia-reperfusion-induced myocardial apoptosis in immature hearts
JM Pearl, DP Nelson, SM Schwartz, CJ Wagner, SM Bauer, EA Setser, JY Duffy
The Annals of Thoracic Surgery 2002
The Interaction Between HSP70 and TNF-?? Expression: A Novel Mechanism for Protection of the Myocardium Against Post-Injury Depression
X Meng, AH Harken
Shock 2002
Monitoring Apoptosis in Real Time
AM Green, ND Steinmetz
The Cancer Journal 2002
Cardiocytic apoptosis and capillary endothelial swellingas morphological evidence of myocardial ischemia in ventricular biopsies from patients with angina and normal coronary arteriograms
S Yamamoto, TN James, K Kawamura, M Nobuyoshi
Coronary Artery Disease 2002
Up-regulation of Bcl-2 through hyperbaric pressure transfection of TGF-β1 ameliorates ischemia-reperfusion injury in rat cardiac allografts
J Grünenfelder, DN Miniati, S Murata, V Falk, EG Hoyt, RC Robbins
The Journal of Heart and Lung Transplantation 2002
Relevance of apoptosis and cell proliferation for survival of patients with dilated cardiomyopathy undergoing partial left ventriculectomy
M Metzger, ML Higuchi, LF Moreira, MJ Chaves, JB Castelli, JM Silvestre, E Bocchi, N Stolf, JA Ramires
European Journal of Clinical Investigation 2002
New Insights Into the Role of Apoptosis in Cardiovascular Disease
PM Kang, P Yue, S Izumo
Circulation Journal 2002
Spatial Distribution of Bax and Bcl-2 in Osteocytes After Bone Fatigue: Complementary Roles in Bone Remodeling Regulation?
O Verborgt, NA Tatton, RJ Majeska, MB Schaffler
Journal of Bone and Mineral Research 2002
Soluble Fas may be a proinflammatory marker after cardiopulmonary bypass in children
U Joashi, SM Tibby, C Turner, A Mayer, C Austin, D Anderson, A Durward, IA Murdoch
The Journal of Thoracic and Cardiovascular Surgery 2002
Hypoxia and acidosis activate cardiac myocyte death through the Bcl-2 family protein BNIP3
LA Kubasiak, OM Hernandez, NH Bishopric, KA Webster
Proceedings of the National Academy of Sciences 2002
Inhibition of mitochondrial calcium-independent phospholipase A2 (iPLA2) attenuates mitochondrial phospholipid loss and is cardioprotective
SD Williams, RA Gottlieb
Biochemical Journal 2002
Apoptosis in myocardial ischaemia and infarction
PA Krijnen, R Nijmeijer, CJ Meijer, CA Visser, CE Hack, HW Niessen
Journal of clinical pathology 2002
Apoptosis in the cardiovascular system
MR Bennett
Heart (British Cardiac Society) 2002
Activation of c-Jun N-terminal kinase promotes survival of cardiac myocytes after oxidative stress
CJ Dougherty, LA Kubasiak, H Prentice, P Andreka, NH Bishopric, KA Webster
Biochemical Journal 2002
Modulation of Ceramide Content and Lack of Apoptosis in the Chronically Hypoxic Neonatal Rat Heart
FF Bitar, H Bitar, ME Sabban, M Nasser, KA Yunis, A Tawil, GS Dbaibo
Pediatric Research 2002
Basic fibroblast growth factor protects cardiac myocytes from iNOS-mediated apoptosis
E Iwai-Kanai, K Hasegawa, M Fujita, M Araki, T Yanazume, S Adachi, S Sasayama
Journal of Cellular Physiology 2002
Exacerbation of myocardial injury in transgenic mice overexpressing FGF-2 is T cell dependent
JT Meij, F Sheikh, SK Jimenez, PW Nickerson, E Kardami, PA Cattini
American journal of physiology. Heart and circulatory physiology 2002
Molecular Pathomechanisms and New Trends in Drug Research
G Schmitz, M Torzewski, S Barlage, W Drobnik
Molecular Pathomechanisms and New Trends in Drug Research 2002
La mitocondria y el corazón
J Marín-García, MJ Goldenthal
Revista Española de Cardiología 2002
A Novel nonpeptidic caspase-3/7 inhibitor, (S)-(+)-5-[1-(2-methoxymethylpyrrolidinyl)sulfonyl]isatin reduces myocardial ischemic injury
JG Chapman, WP Magee, HA Stukenbrok, GE Beckius, AJ Milici, WR Tracey
European Journal of Pharmacology 2002
Cardioprotective effects of the serine protease inhibitor aprotinin after regional ischemia and reperfusion on the beating heart
D Pruefer, U Buerke, M Khalil, M Dahm, H Darius, H Oelert, M Buerke
The Journal of Thoracic and Cardiovascular Surgery 2002
Advances in Experimental Medicine and Biology
KA Webster, DJ Discher, OM Hernandez, K Yamashita, NH Bishopric
Advances in experimental medicine and biology 2002
Reactive oxygen species induce cardiomyocyte apoptosis partly through TNF-alpha
Ryuichi Aikawa, Yuko Nitta-Komatsubara, Sumiyo Kudoh, Hiroyuki Takano, Toshio Nagai, Yoshio Yazaki, Ryozo Nagai, Issei Komuro
Cytokine 2002
Apoptosis in myocardial infarction
M Rodríguez, BR Lucchesi, J Schaper
Annals of Medicine 2002
Adenosine A 3 receptor activation protects the myocardium from reperfusion/reoxygenation injury
HL Maddock, MM Mocanu, DM Yellon
American journal of physiology. Heart and circulatory physiology 2002
Burn plasma mediates cardiac myocyte apoptosis via endotoxin
DL Carlson, E Lightfoot, DD Bryant, SB Haudek, D Maass, J Horton, BP Giroir
American journal of physiology. Heart and circulatory physiology 2002
Losing heart: the role of apoptosis in heart disease—a novel therapeutic target?
C Gill, R Mestril, A Samali
The FASEB Journal 2002
Verapamil Reduces Coronary Endothelium Damage and Cardiomyocyte Necrosis but not Apoptosis after Ischemia and Reperfusion: Ex Vivo Study in Rat Hearts
PD Napoli, AA Taccardi, A Grilli, M Felaco, LD Gioacchino, RD Caterina, A Barsotti
International journal of immunopathology and pharmacology 2002
Contribution of Macrophage Migration Inhibitory Factor to Extracellular Signal-regulated Kinase Activation by Oxidative Stress in Cardiomyocytes
J Fukuzawa, J Nishihira, N Hasebe, T Haneda, J Osaki, T Saito, T Nomura, T Fujino, N Wakamiya, K Kikuchi
The Journal of biological chemistry 2002
Calpain and Mitochondria in Ischemia/Reperfusion Injury
M Chen, DJ Won, S Krajewski, RA Gottlieb
The Journal of biological chemistry 2002
Selected Contribution: Hypothermic protection of the ischemic heart via alterations in apoptotic pathways as assessed by gene array analysis
XH Ning, SH Chen, CS Xu, L Li, LY Yao, K Qian, JJ Krueger, OM Hyyti, MA Portman
Journal of applied physiology 2002
Absence of inducible nitric oxide synthase modulates early reperfusion-induced NF-κB and AP-1 activation and enhances myocardial damage
B Zingarelli, PW Hake, Z Yang, M Oconnor, AL Denenberg, HR Wong
The FASEB Journal 2002
HEME OXYGENASE-1 OVEREXPRESSION PROTECTS RAT HEARTS FROM COLD ISCHEMIA/REPERFUSION INJURY VIA AN ANTIAPOPTOTIC PATHWAY1:
M Katori, R Buelow, B Ke, J Ma, AJ Coito, S Iyer, D Southard, RW Busuttil, JW Kupiec-Weglinski
Transplantation 2002
Amelioration of myocardial global ischemia/reperfusion injury with volume-regulatory chloride channel inhibitors in vivo1:
K Mizoguchi, H Maeta, A Yamamoto, M Oe, H Kosaka
Transplantation 2002
Rac-Dependent Monocyte Chemoattractant Protein-1 Production Is Induced by Nutrient Deprivation
NH Lopes, SS Vasudevan, D Gregg, B Selvakumar, PJ Pagano, H Kovacic, PJ Goldschmidt-Clermont
Circulation research 2002
Persistent Infarct–Related Artery Occlusion Is Associated With an Increased Myocardial Apoptosis at Postmortem Examination in Humans Late After an Acute Myocardial Infarction
A Abbate, R Bussani, GG Biondi-Zoccai, R Rossiello, F Silvestri, F Baldi, LM Biasucci, A Baldi
Circulation 2002
Nitric Oxide Mediates the Antiapoptotic Effect of Insulin in Myocardial Ischemia-Reperfusion: The Roles of PI3-Kinase, Akt , and Endothelial Nitric Oxide Synthase Phosphorylation
F Gao, E Gao, TL Yue, EH Ohlstein, BL Lopez, TA Christopher, XL Ma
Circulation 2002
Mitochondria in Pathogenesis
JJ Lemasters, AL Nieminen
2002
Viral Gene Transfer of the Antiapoptotic Factor Bcl-2 Protects Against Chronic Postischemic Heart Failure
S Chatterjee, AS Stewart, LT Bish, V Jayasankar, EM Kim, T Pirolli, J Burdick, YJ Woo, TJ Gardner, HL Sweeney
Circulation 2002
Dopamine Treatment of Postischemic Contractile Dysfunction Rapidly Induces Calcium-Dependent Pro-Apoptotic Signaling
C Stamm, I Friehs, DB Cowan, H Cao-Danh, YH Choi, LF Duebener, FX McGowan, PJ del Nido
Circulation 2002
Noninvasive detection of cell death: From tracking epitaphs to counting coffins
J Narula, B Zaret
Journal of Nuclear Cardiology 2002
Cyclooxygenase-1 and -2 knockout mice demonstrate increased cardiac ischemia/reperfusion injury but are protected by acute preconditioning
MG Camitta, SA Gabel, P Chulada, JA Bradbury, R Langenbach, DC Zeldin, E Murphy
Circulation 2001
p53 activates the mitochondrial death pathway and apoptosis of ventricular myocytes independent of de novo gene transcription
KM Regula, LA Kirshenbaum
Journal of Molecular and Cellular Cardiology 2001
Reappearance of myocytes in ovine infarcts produced by six hours of complete ischemia followed by reperfusion
FW Bowen, T Hattori, N Narula, IS Salgo, T Plappert, MG st. Sutton, LH Edmunds
The Annals of Thoracic Surgery 2001
Cardioprotective Effects of Transforming Growth Factor-β1 During Early Reoxygenation or Reperfusion Are Mediated by p42/p44 MAPK
GF Baxter, MM Mocanu, BK Brar, DS Latchman, DM Yellon
Journal of Cardiovascular Pharmacology 2001
The role of apoptotic cell death in cardiovascular disease
R McLaughlin, CJ Kelly, E Kay, D Bouchier-Hayes
Irish Journal of Medical Science 2001
Cardiac apoptosis: from organ failure to allograft rejection
ME Hinescu
Journal of Cellular and Molecular Medicine 2001
Fibroblast growth factors in myocardial ischemia / reperfusion injury and ischemic preconditioning
P Cuevas, F Carceller, G Giménez-Gallego
Journal of Cellular and Molecular Medicine 2001
Adenosine-enhanced ischemic preconditioning modulates necrosis and apoptosis: effects of stunning and ischemia–reperfusion
B Stadler, J Phillips, Y Toyoda, M Federman, S Levitsky, JD McCully
The Annals of Thoracic Surgery 2001
What’s in a name? Would that which we call death by any other name be less tragic?
J Narula, R Baliga
The Annals of Thoracic Surgery 2001
Effect of endothelin receptor antagonist on lung allograft apoptosis and NOSII expression
MJ Shaw, H Shennib, N Bousette, EH Ohlstein, A Giaid
The Annals of Thoracic Surgery 2001
Time-Dependent Apoptotic Development and Pro-apoptotic Genes Expression in Rat Heart After Myocardial Infarction
YZ Zhu, YC Zhu, ZJ Wang, Q Lu, HS Lee, T Unger
The Japanese Journal of Pharmacology 2001
Postischemic apoptosis and functional recovery after angiotensin II type 1 receptor blockade in isolated working rat hearts
R Moudgil, V Menon, Y Xu, S Musat-Marcu, D Kumar, BI Jugdutt
Journal of Hypertension 2001
Detection of Apoptosis in Ischemic Heart
MS Rodríguez-Calvo, MN Tourret, L Concheiro, JI Muñoz, JM Suárez-Peñaranda
The American Journal of Forensic Medicine and Pathology 2001
Resuscitation-induced pulmonary apoptosis and intracellular adhesion molecule-1 expression in rats are attenuated by the use of Ketone Ringer’s solution1 1The opinions and assertions contained here are the private ones of the authors and are not to be construed as official or reflecting the views of the Department of Defense at large. This article was prepared by United States Government employees and cannot be copyrighted and may be copied with restriction
HB Alam, B Austin, E Koustova, P Rhee
Journal of the American College of Surgeons 2001
Activation of Mitogen-Activated Protein Kinases in the Non-Ischemic Myocardium of an Acute Myocardial Infarction in Rats
K Yoshida, M Yoshiyama, T Omura, Y Nakamura, S Kim, K Takeuchi, H Iwao, J Yoshikawa
Japanese Circulation Journal 2001
Coronary Reperfusion Following Ischemia. Different Expression of Bcl-2 and Bax Proteins, and Cardiomyocyte Apoptosis
Z Xie, T Koyama, J Suzuki, Y Fujii, H Togashi, H Sawa, K Nagashima
Japanese Heart Journal 2001
Mechanism of the Cardioprotective Effect of Inhibition of the Renin-Angiotensin System on Ischemia/Reperfusion-Induced Myocardial Injury
LX WANG, M IDEISHI, E YAHIRO, H URATA, K ARAKAWA, K SAKU
Hypertension Research 2001
Apoptosis and the Heart
LD Tomei, SR Umansky
Annals of the New York Academy of Sciences 2001
Fatty Acid-Induced Apoptosis in Neonatal Cardiomyocytes: Redox Signaling
GC Sparagna, DL Hickson-Bick, LM Buja, JB McMillin
Antioxidants & Redox Signaling 2001
Pharmacology of Caspase Inhibitors in Rabbit Cardiomyocytes Subjected to Metabolic Inhibition and Recovery
HL Li, E Karwatowska-Prokopczuk, M Mutomba, J Wu, D Karanewsky, K Valentino, RL Engler, RA Gottlieb
Antioxidants & Redox Signaling 2001
SIGNAL TRANSDUCTION OF NITRIC OXIDE DONOR-INDUCED PROTECTION IN HYDROGEN PEROXIDE-MEDIATED APOPTOSIS IN H9C2 CARDIOMYOBLASTS
HJ Chae, HR Kim, YG Kwak, JK Ko, CU Joo, SW Chae, SW Chae
Immunopharmacology and Immunotoxicology 2001
Simvastatin Induces Apoptosis of Cultured Rat Cardiomyocytes
D El-Ani, R Zimlichman
Journal of Basic and Clinical Physiology and Pharmacology 2001
Heart-targeted overexpression of caspase3 in mice increases infarct size and depresses cardiac function
G Condorelli, R Roncarati, J Ross, A Pisani, G Stassi, M Todaro, S Trocha, A Drusco, Y Gu, MA Russo, G Frati, SP Jones, DJ Lefer, C Napoli, CM Croce
Proceedings of the National Academy of Sciences 2001
Molecular and cellular mechanisms of cardiotoxicity
YJ Kang
Environmental Health Perspectives 2001
Phosphoinositide 3-kinase accelerates necrotic cell death during hypoxia
T Aki, Y Mizukami, Y Oka, K Yamaguchi, K Uemura, T Fujimiya, K Yoshida
Biochemical Journal 2001
Chronic Hypoxia Induces Apoptosis in Cardiac Myocytes: A Possible Role for Bcl-2-like Proteins
F Jung, U Weiland, RA Johns, C Ihling, S Dimmeler
Biochemical and Biophysical Research Communications 2001
Heart Physiology and Pathophysiology
NS Dhalla, RM Temsah, T Netticadan, MS Sandhu
Heart Physiology and Pathophysiology 2001
Postischemic apoptosis and functional recovery after angiotensin II type 1 receptor blockade in isolated working rat hearts:
R Moudgil, V Menon, Y Xu, S Musat-Marcu, D Kumar, BI Jugdutt
Journal of Hypertension 2001
Surgical Research
J Rozga, AA Demetriou
Surgical Research 2001
Transgene overexpression of alphaB crystallin confers simultaneous protection against cardiomyocyte apoptosis and necrosis during myocardial ischemia and reperfusion
PS Ray, JL Martin, EA Swanson, H Otani, WH Dillmann, DK Das
The FASEB Journal 2001
Pericardial fluid from patients with ischemic heart disease induces myocardial cell apoptotis via an oxidant stress-sensitive p38 mitogen-activated protein kinase pathway
A Iwakura, M Fujita, K Hasegawa, S Toyokuni, T Sawamura, R Nohara, S Sasayama, M Komeda
Journal of Molecular and Cellular Cardiology 2001
Apoptotic Cell Death Makes a Minor Contribution to Reperfusion Injury in Skeletal Muscle in the Rat
PA Cowled, L Leonardos, SH Millard, RA Fitridge
European Journal of Vascular and Endovascular Surgery 2001
Angiotensin receptors: signaling, vascular pathophysiology, and interactions with ceramide
H Gavras, HR Brunner
American journal of physiology. Heart and circulatory physiology 2001
The biology of apoptosis
FJ Geske, LE Gerschenson
Human Pathology 2001
Important role of energy-dependent mitochondrial pathways in cultured rat cardiac myocyte apoptosis
J Shiraishi, T Tatsumi, N Keira, K Akashi, A Mano, S Yamanaka, S Matoba, J Asayama, T Yaoi, S Fushiki, H Fliss, M Nakagawa
American journal of physiology. Heart and circulatory physiology 2001
Serpin protein CrmA suppresses hypoxia-mediated apoptosis of ventricular myocytes
RM Gurevich, KM Regula, LA Kirshenbaum
Circulation 2001
Vein adaptation to arterialization in an experimental model
A Westerband, D Crouse, LC Richter, ML Aguirre, CC Wixon, DC James, JL Mills, GC Hunter, RL Heimark
Journal of Vascular Surgery 2001
APOPTOSIS IN CARDIAC TRANSPLANT REJECTION
LW Miller, DJ Granville, J Narula, BM McManus
Cardiology Clinics 2001
Targeted inhibition of the small GTPase protects against ischemia/reperfusion liver injury in mice
M Ozaki, S Deshpande, P Angkeow, J Bellan, CJ Lowenstein, MC Dinauer, P Goldschmidt-Clermont, S Suzuki, K Irani
Transplantation Proceedings 2001
CELL DEATH IN THE HEART
RA Lockshin, CO Facey, Z Zakeri
Cardiology Clinics 2001
GENE THERAPY AND PHARMACEUTICAL MODULATION OF APOPTOSIS
Y Chandrashekhar, S Sen
Cardiology Clinics 2001
Apoptosis in myocarditis and dilated cardiomyopathy: Does enterovirus genome persistence protect from apoptosis? — An endomyocardial biopsy study
P Alter, M Jobmann, E Meyer, S Pankuweit, B Maisch
Cardiovascular Pathology 2001
Regulation of renal tubular cell apoptosis and proliferation after ischemic injury to a solitary kidney
R Oberbauer, C Schwarz, HM Regele, C Hansmann, TW Meyer, G Mayer
Journal of Laboratory and Clinical Medicine 2001
Adenosine Attenuates Reperfusion-induced Apoptotic Cell Death by Modulating Expression of Bcl-2 and Bax Proteins
ZQ Zhao, JM Budde, C Morris, NP Wang, DA Velez, S Muraki, RA Guyton, J Vinten-Johansen
Journal of Molecular and Cellular Cardiology 2001
Chelerythrine Rapidly Induces Apoptosis through Generation of Reactive Oxygen Species in Cardiac Myocytes
S Yamamoto, K Seta, C Morisco, SF Vatner, J Sadoshima
Journal of Molecular and Cellular Cardiology 2001
Role of Opioid δ1Receptors, Mitochondrial KATPChannels, and Protein Kinase C during Cardiocyte Apoptosis
H Liu, HY Zhang, BC McPherson, T Baman, S Roth, Z Shao, X Zhu, Z Yao
Journal of Molecular and Cellular Cardiology 2001
Phosphorylation of proteins and apoptosis induced by c-Jun N-terminal kinase1 activation in rat cardiomyocytes by H2O2 stimulation
Y Mizukami, T Okamura, T Miura, M Kimura, K Mogami, N Todoroki-Ikeda, S Kobayashi, M Matsuzaki
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research 2001
The Oxidative Stress Hypothesis of Congestive Heart Failure
S Mak, GE Newton
Chest 2001
Orphan G Protein-coupled Receptor, GPR41, Induces Apoptosis via a p53/Bax Pathway during Ischemic Hypoxia and Reoxygenation
M Kimura, Y Mizukami, T Miura, K Fujimoto, S Kobayashi, M Matsuzaki
The Journal of biological chemistry 2001
Annexin V staining during reperfusion detects cardiomyocytes with unique properties
P Narayan, RM Mentzer, RD Lasley
American journal of physiology. Heart and circulatory physiology 2001
Apoptosis in the ischemic reperfused myocardium
CR Holleyman, DF Larson
Perfusion 2001
Induction of Apoptosis and Fas Receptor/Fas Ligand Expression by Ischemia/Reperfusion in Cardiac Myocytes Requires Serine 727 of the STAT-1 Transcription Factor but Not Tyrosine 701
A Stephanou, TM Scarabelli, BK Brar, Y Nakanishi, M Matsumura, RA Knight, DS Latchman
The Journal of biological chemistry 2001
Distinct initiator caspases are required for the induction of apoptosis in cardiac myocytes during ischaemia versus reperfusion injury
A Stephanou, B Brar, Z Liao, T Scarabelli, RA Knight, DS Latchman
Cell Death and Differentiation 2001
Preconditioning attenuates apoptosis and necrosis: role of protein kinase Cε and -δ isoforms
H Liu, BC McPherson, Z Yao
American journal of physiology. Heart and circulatory physiology 2001
Increased [Mg 2+ ] o reduces Ca 2+ influx and disruption of mitochondrial membrane potential during reoxygenation
MN Sharikabad, KM Østbye, O Brørs
American journal of physiology. Heart and circulatory physiology 2001
Cardiomyocyte apoptosis and ventricular remodeling after myocardial infarction in rats
E Palojoki, A Saraste, A Eriksson, K Pulkki, M Kallajoki, LM Voipio-Pulkki, I Tikkanen
American journal of physiology. Heart and circulatory physiology 2001
Overexpression of Bcl-2 attenuates apoptosis and protects against myocardial I/R injury in transgenic mice
Z Chen, CC Chua, YS Ho, RC Hamdy, BH Chua
American journal of physiology. Heart and circulatory physiology 2001
Erratum: Seeing death in the living
RA Gottlieb, RN Kitsis
Nature Medicine 2001
A SUBPOPULATION OF MITOCHONDRIA PREVENTS CYTOSOLIC CALCIUM OVERLOAD IN ENDOTHELIAL CELLS AFTER COLD ISCHEMIA/REPERFUSION:
A Amberger, H Weiss, T Haller, G Kck, M Hermann, M Widschwendter, R Margreiter
Transplantation 2001
Mitochondrial ATP-Sensitive Potassium Channels Inhibit Apoptosis Induced by Oxidative Stress in Cardiac Cells
M Akao, A Ohler, B ORourke, E Marbán
Circulation research 2001
In Cardiomyocyte Hypoxia, Insulin-Like Growth Factor-I-Induced Antiapoptotic Signaling Requires Phosphatidylinositol-3-OH-Kinase-Dependent and Mitogen-Activated Protein Kinase-Dependent Activation of the Transcription Factor cAMP Response Element-Binding Protein
FB Mehrhof, FU Müller, MW Bergmann, P Li, Y Wang, W Schmitz, R Dietz, R von Harsdorf
Circulation 2001
Apoptosis of Endothelial Cells Precedes Myocyte Cell Apoptosis in Ischemia/Reperfusion Injury
T Scarabelli, A Stephanou, N Rayment, E Pasini, L Comini, S Curello, R Ferrari, R Knight, D Latchman
Circulation 2001
Annexin-V imaging for noninvasive detection of cardiac allograft rejection
J Narula, ER Acio, N Narula, LE Samuels, B Fyfe, D Wood, JM Fitzpatrick, PN Raghunath, JE Tomaszewski, C Kelly, N Steinmetz, A Green, JF Tait, J Leppo, FG Blankenberg, D Jain, HW Strauss
Nature Medicine 2001
Inhibition of C-Jun N-Terminal Kinase 1, but Not c-Jun N-Terminal Kinase 2, Suppresses Apoptosis Induced by Ischemia/Reoxygenation in Rat Cardiac Myocytes
D Hreniuk, M Garay, W Gaarde, BP Monia, RA McKay, CL Cioffi
Molecular pharmacology 2001
Intramitochondrial pyruvate attenuates hydrogen peroxide-induced apoptosis in bovine pulmonary artery endothelium
Y H Kang, S J Chung, I J Kang, J H Park, R Bünger
Molecular and Cellular Biochemistry 2001
Myocardial protection from ischemia-reperfusion injury by endogenous and exogenous hepatocyte growth factor
Teruya Nakamura, Shinya Mizuno, Kunio Matsumoto, Yoshiki Sawa, Hikaru Matsuda, Toshikazu Nakamura
Journal of Clinical Investigation 2000
Ischemic cardiomyopathy and the cellular renin-angiotensin system
P Anversa, A Leri, B Li, Y Liu, SD Somma, J Kajstura
The Journal of Heart and Lung Transplantation 2000
DNA damage in human leukocytes after ischemia/reperfusion injury
C Willy, S Dahouk, C Starck, W Kaffenberger, H Gerngroß, UG Plappert
Free radical biology & medicine 2000
Caspase inhibition and limitation of myocardial infarct size: protection against lethal reperfusion injury
MM Mocanu, GF Baxter, DM Yellon
British Journal of Pharmacology 2000
Apoptosis: mechanisms and clinical implications
PC Kam, NI Ferch
Anaesthesia 2000
Sensitization of tumor cells to Fas killing through overexpression of heat-shock transcription factor 1
W Xia, R Voellmy, NL Spector
Journal of Cellular Physiology 2000
Apoptosis induced by ischemia and reperfusion in experimental lung transplantation
U Stammberger, A Gaspert, S Hillinger, P Vogt, B Odermatt, W Weder, RA Schmid
The Annals of Thoracic Surgery 2000
Hypothermic circulatory arrest causes multisystem vascular endothelial dysfunction and apoptosis
WA Cooper, IG Duarte, VH Thourani, M Nakamura, NP Wang, WM Brown, JP Gott, J Vinten-Johansen, RA Guyton
The Annals of Thoracic Surgery 2000
Simvastatin enhanced sodium nitroprusside-induced apoptosis of smooth muscle cells
H Fujita, S Shimotsuura, A Yanagisawa, I Morita, S Murota, K Ishikawa
Atherosclerosis 2000
Clinico-pathologic, Immunohistochemical, and TUNEL Study in Early Cardiac Allograft Failure
A Panizo-Santos
Cardiovascular Pathology 2000
Cell Death in Human Lung Transplantation: Apoptosis Induction in Human Lungs During Ischemia and After Transplantation
S Fischer, SD Cassivi, AM Xavier, JA Cardella, E Cutz, V Edwards, M Liu, S Keshavjee
Annals of Surgery 2000
Apoptosis inhibition of cellular proliferation by II: possible implication and perspectives
I Mucsi, L Rosivall, B Antus
Acta Physiologica Hungarica 2000
Cardiotrophin-1
DS Latchman
Pharmacology & Therapeutics 2000
Is apoptosis present in progression to chronic hypertensive heart failure?
T Tamura, S Said, W Lu, J Harris, D Neufeld, JA Burbach, AM Gerdes
Journal of Cardiac Failure 2000
Insights into adenosine A1 and A3 receptors function: Cardiotoxicity and cardioprotection
V Shneyvays, N Safran, I Halili-Rutman, A Shainberg
Drug Development Research 2000
Visualisation of cell death in vivo in patients with acute myocardial infarction
L Hofstra, IH Liem, EA Dumont, HH Boersma, WL van Heerde, PA Doevendans, E DeMuinck, HJ Wellens, GJ Kemerink, CP Reutelingsperger, GA Heidendal
The Lancet 2000
Cell death in human lung transplantation: apoptosis induction in human lungs during ischemia and after transplantation
S Fischer, SD Cassivi, AM Xavier, JA Cardella, E Cutz, V Edwards, M Liu, S Keshavjee
Annals of Surgery 2000
In vivo myocardial infarct size reduction by a caspase inhibitor administered after the onset of ischemia
JQ Huang, S Radinovic, P Rezaiefar, SC Black
European Journal of Pharmacology 2000
Cytokines and their receptors in cardiovascular diseases — role of gp130 signalling pathway in cardiac myocyte growth and maintenance
K Yamauchi-Takihara, T Kishimoto
International Journal of Experimental Pathology 2000
Cell and Molecular Response to Stress
KA Webster
Cell and Molecular Response to Stress 2000
Regulation of the activity of caspases by L-carnitine and palmitoylcarnitine
MC Mutomba, H Yuan, M Konyavko, S Adachi, CB Yokoyama, V Esser, JD McGarry, BM Babior, RA Gottlieb
FEBS Letters 2000
Preservation injury of the liver: mechanisms and novel therapeutic strategies
M Bilzer, AL Gerbes
Journal of Hepatology 2000
IL-4 induces apoptosis of endothelial cells through the caspase-3-dependent pathway
YW Lee, H Kühn, B Hennig, M Toborek
FEBS Letters 2000
On the nature of cell death during remodeling of hypertrophied human myocardium
S Yamamoto, K Sawada, H Shimomura, K Kawamura, TN James
Journal of Molecular and Cellular Cardiology 2000
Morphological and molecular characterization of adult cardiomyocyte apoptosis during hypoxia and reoxygenation
PM Kang, A Haunstetter, H Aoki, A Usheva, S Izumo
Circulation research 2000
Quantitative determination of ceramide using diglyceride kinase
DK Perry, A Bielawska, YA Hannun
Methods in enzymology 2000
In vivo models of myocardial ischemia and reperfusion injury
SC Black
Journal of Pharmacological and Toxicological Methods 2000
Impact of ischemia/reperfusion injury and early inflammatory responses in kidney transplantation
DD Koo, SV Fuggle
Transplantation Reviews 2000
Inhibition of hypoxia/reoxygenation-induced apoptosis by an antisense oligonucleotide targeted to JNK1 in human kidney cells
M Garay, W Gaarde, BP Monia, P Nero, CL Cioffi
Biochemical Pharmacology 2000
Interleukin 6 induction in the canine myocardium after cardiopulmonary bypass
WJ Dreyer, SC Phillips, ML Lindsey, P Jackson, NE Bowles, LH Michael, ML Entman
The Journal of Thoracic and Cardiovascular Surgery 2000
Pathologic Assessment of Myocardial Cell Necrosis and Apoptosis after Ischemia and Reperfusion with Molecular and Morphological Markers
E Takashi, M Ashraf
Journal of Molecular and Cellular Cardiology 2000
Caspase Activation and Mitochondrial Cytochrome C Release during Hypoxia-mediated Apoptosis of Adult Ventricular Myocytes
D Moissac, RM Gurevich, H Zheng, PK Singal, LA Kirshenbaum
Journal of Molecular and Cellular Cardiology 2000
Apoptosis is Initiated by Myocardial Ischemia and Executed During Reperfusion
B Freude, TN Masters, F Robicsek, A Fokin, S Kostin, R Zimmermann, C Ullmann, S Lorenz-Meyer, J Schaper
Journal of Molecular and Cellular Cardiology 2000
Unresolved Issues Regarding the Role of Apoptosis in the Pathogenesis of Ischemic Injury and Heart Failure
A Elsässer, K Suzuki, J Schaper
Journal of Molecular and Cellular Cardiology 2000
Apoptosis in Dilated Cardiomyopathy
BK Hong, HM Kwon, KH Byun, DS Kim, EY Choi, TS Kang, SM Kang, KJ Chun, YS Jang, HS Kim
The Korean Journal of Internal Medicine 2000
Apoptosis in dilated cardiomyopathy
B K Hong, H M Kwon, K H Byun, D Kim, E Y Choi, T S Kang, S M Kang, K J Chun, Y Jang, H S Kim, M Kim
The Korean Journal of Internal Medicine 2000
Chinonin, a novel drug against cardiomyocyte apoptosis induced by hypoxia and reoxygenation
J G Shen, X S Quo, B Jiang, M Li, W Xin, B L Zhao
Biochimica et Biophysica Acta 2000
Does programmed cell death (apoptosis) play a role in the development of multiple organ dysfunction in critically ill patients? A review and a theoretical framework:
ED Papathanassoglou, JA Moynihan, MH Ackerman
Critical Care Medicine 2000
Histological assessment of apoptotic cell death in cardiomyopathies
NG Kavantzas, AC Lazaris, EV Agapitos, J Nanas, PS Davaris
Pathology 2000
Oxidative Stress Developed During Open Heart Surgery Induces Apoptosis: Reduction of Apoptotic Cell Death by Ebselen, a Glutathione Peroxidase Mimic:
N Maulik, T Yoshida
Journal of Cardiovascular Pharmacology 2000
Myofibrillar disruption in hypocontractile myocardium showing perfusion-contraction matches and mismatches
AJ Sherman, FJ Klocke, RS Decker, ML Decker, KA Kozlowski, KR Harris, S Hedjbeli, Y Yaroshenko, S Nakamura, MA Parker, PA Checchia, DB Evans
American journal of physiology. Heart and circulatory physiology 2000
A direct requirement of nuclear factor-κB for suppression of apoptosis in ventricular myocytes
S Mustapha, A Kirshner, DD Moissac, LA Kirshenbaum
American journal of physiology. Heart and circulatory physiology 2000
Endotoxin infusion in rats induces apoptotic and survival pathways in hearts
TE McDonald, MN Grinman, CM Carthy, KR Walley
American journal of physiology. Heart and circulatory physiology 2000
Influence of simulated ischemia on apoptosis induction by oxidative stress in adult cardiomyocytes of rats
J Inserte, G Taimor, B Hofstaetter, D Garcia-Dorado, HM Piper
American journal of physiology. Heart and circulatory physiology 2000
Urocortin Protects against Ischemic and Reperfusion Injury via a MAPK-dependent Pathway
BK Brar, AK Jonassen, A Stephanou, G Santilli, J Railson, RA Knight, DM Yellon, DS Latchman
The Journal of biological chemistry 2000
Cardioprotective effect of chronic hyperglycemia: effect on hypoxia-induced apoptosis and necrosis
SW Schaffer, CB Croft, V Solodushko
American journal of physiology. Heart and circulatory physiology 2000
Ischemia-induced STAT-1 Expression and Activation Play a Critical Role in Cardiomyocyte Apoptosis
A Stephanou, BK Brar, TM Scarabelli, AK Jonassen, DM Yellon, MS Marber, RA Knight, DS Latchman
The Journal of biological chemistry 2000
NUCLEAR FACTOR-??B TRANSCRIPTION FACTOR DECOY TREATMENT INHIBITS GRAFT CORONARY ARTERY DISEASE AFTER CARDIAC TRANSPLANTATION IN RODENTS1:
BT Feeley, DN Miniati, AK Park, EG Hoyt, RC Robbins
Transplantation 2000
Lactated Ringer???s Solution and Hetastarch but Not Plasma Resuscitation after Rat Hemorrhagic Shock Is Associated with Immediate Lung Apoptosis by the Up-regulation of the Bax Protein:
S Deb, L Sun, B Martin, E Talens, D Burris, C Kaufmann, N Rich, P Rhee
The Journal of trauma 2000
Inhibition of the Rac1 GTPase protects against nonlethal ischemia/reperfusion-induced necrosis and apoptosis in vivo
M Ozaki, SS Deshpande, P Angkeow, J Bellan, CJ Lowenstein, MC Dinauer, PJ Goldschmidt-Clermont, K Irani
The FASEB Journal 2000
ISCHEMIA REPERFUSION-INDUCED DYNAMIC CHANGES OF PROTEIN TYROSINE PHOSPHORYLATION DURING HUMAN LUNG TRANSPLANTATION1:
S Keshavjee, XM Zhang, S Fischer, M Liu
Transplantation 2000
Beneficial Effects of Intracoronary Adenosine as an Adjunct to Primary Angioplasty in Acute Myocardial Infarction
M Marzilli, E Orsini, P Marraccini, R Testa
Circulation 2000
Rapid Activation of Neutral Sphingomyelinase by Hypoxia-Reoxygenation of Cardiac Myocytes
OM Hernandez, DJ Discher, NH Bishopric, KA Webster
Circulation research 2000
Fas-Mediated Apoptosis in Adriamycin-Induced Cardiomyopathy in Rats: In Vivo Study
T Nakamura, Y Ueda, Y Juan, S Katsuda, H Takahashi, E Koh
Circulation 2000
Involvement of CD95/Apo1/Fas in Cell Death After Myocardial Ischemia
I Jeremias, C Kupatt, A Martin-Villalba, H Habazettl, J Schenkel, P Boekstegers, KM Debatin
Circulation 2000
Cardiomyocyte Death Induced by Myocardial Ischemia and Reperfusion: Measurement With Recombinant Human Annexin-V in a Mouse Model
EA Dumont, L Hofstra, WL van Heerde, S van den Eijnde, PA Doevendans, E DeMuinck, MA Daemen, JF Smits, P Frederik, HJ Wellens, MJ Daemen, CP Reutelingsperger
Circulation 2000
Textbook of Angiology
JB Chang
2000
Apoptosis and Its Modulation by Drugs
RG Cameron, G Feuer
2000
Apoptosis in Cardiac Biology
H Schunkert, GA Riegger
2000
The Hypertrophied Heart
N Takeda, M Nagano, NS Dhalla
2000
Pathologie des Endokard, der Kranzarterien und des Myokard
W Hort
2000
An Early Oxygen-Dependent Step Is Required for Dexamethasone-Induced Apoptosis of Immature Mouse Thymocytes
JF Torres-Roca, JW Tung, DR Greenwald, JM Brown, LA Herzenberg, LA Herzenberg, PD Katsikis
Journal of immunology (Baltimore, Md. : 1950) 2000
Is Apoptosis a Diagnostic Marker of Acute Myocardial Infarction?
FR Piro, CR di Gioia, P Gallo, C Giordano, G d'Amati
Archives of pathology & laboratory medicine 2000
Cell death, tissue hypoxia and the progression of heart failure
H N Sabbah, V G Sharov, S Goldstein
Heart Failure Reviews 2000
Effect of Flos carthami on stress-activated protein kinase activity in the isolated reperfused rat heart
Y L Siow, P C Choy, W M Leung, K O
Molecular and Cellular Biochemistry 2000
Burden of myocardial damage in cardiac allograft rejection: Scintigraphic evidence of myocardial injury and histologic evidence of myocyte necrosis and apoptosis
M Puig
Journal of Nuclear Cardiology 2000
Hypoxia-activated apoptosis of cardiac myocytes requires reoxygenation or a pH shift and is independent of p53
NH Bishopric, DJ Discher, S Kaiser, O Hernandez, B Sato, J Zang, KA Webster
Journal of Clinical Investigation 1999
Mitochondrial physiology and pathology; concepts of programmed death of organelles, cells and organisms
VP Skulachev
Molecular Aspects of Medicine 1999
Broad-spectrum cardioprotection with adenosine
J Vinten-Johansen, VH Thourani, RS Ronson, JE Jordan, ZQ Zhao, M Nakamura, D Velez, RA Guyton
The Annals of Thoracic Surgery 1999
Altered gene expression during hypoxia and reoxygenation of the heart
L Piacentini, JS Karliner
Pharmacology & Therapeutics 1999
Morphologic criteria and detection of apoptosis
A Saraste
Herz 1999
Calcium channel blockers, apoptosis and cancer: is there a biologic relationship?
RP Mason
Journal of the American College of Cardiology 1999
Ischemic preconditioning reduces neutrophil accumulation and myocardial apoptosis
NP Wang, BL Bufkin, M Nakamura, ZQ Zhao, JN Wilcox, KO Hewan-Lowe, RA Guyton, J Vinten-Johansen
The Annals of Thoracic Surgery 1999
Oxygen Free Radical Signaling in Ischemic Preconditioninga
DK Das, RM Engelman, N Maulik
Annals of the New York Academy of Sciences 1999
Apoptosis in Myocardial Ischemia-Reperfusion
RA Gottlieb, RL Engler
Annals of the New York Academy of Sciences 1999
Differential Regulation of Apoptosis by Ischemia-Reperfusion and Ischemic Adaptationa
N Maulik, H Sasaki, N Galang
Annals of the New York Academy of Sciences 1999
Emerging therapeutic targets in caspase-dependent disease
CB McBride, LT McPhail, JD Steeves
Expert Opinion on Therapeutic Targets 1999
Calpain Inhibitor-1 Reduces Infarct Size and DNA Fragmentation of Myocardium in Ischemic/Reperfused Rat Heart
H Iwamoto, T Miura, T Okamura, K Shirakawa, M Iwatate, S Kawamura, H Tatsuno, Y Ikeda, M Matsuzaki
Journal of Cardiovascular Pharmacology 1999
Antioxidative Properties of Pyruvate and Protection of the Ischemic Rat Heart During Cardioplegia
P Dobsak, C Courderot-Masuyer, M Zeller, C Vergely, A Laubriet, M Assem, JC Eicher, JR Teyssier, JE Wolf, L Rochette
Journal of Cardiovascular Pharmacology 1999
Increased p53 protein expression in human failing myocardium
H Song, JV Conte, AH Foster, JS McLaughlin, C Wei
The Journal of Heart and Lung Transplantation 1999
Effects of calcium channel blockers on cellular apoptosis
RP Mason
Cancer 1999
Elevated DNase activity and caspase expression in association with apoptosis in failing ischemic sheep left ventricles
L Jiang, Y Huang, T Yuasa, S Hunyor, CG Remedios
Electrophoresis 1999
Ischemia-reperfusion in the adult mouse heart
G Azhar, W Gao, L Liu, JY Wei
Experimental Gerontology 1999
A specific inhibitor of apoptosis decreases tissue injury after intestinal ischemia-reperfusion in mice
A Farber, JP Connors, RM Friedlander, RJ Wagner, RJ Powell, JL Cronenwett
Journal of Vascular Surgery 1999
Allograft heart valves: The role of apoptosis-mediated cell loss
SL Hilbert, RE Luna, J Zhang, Y Wang, RA Hopkins, ZX Yu, VJ Ferrans
The Journal of Thoracic and Cardiovascular Surgery 1999
Redox Regulation of NF-κB and AP-1 in Ischemic Reperfused Heart
H Sasaki, N Galang, N Maulik
Antioxidants & Redox Signaling 1999
Cardiomyocyte apoptosis and progression of heart failure to transplantation
Saraste, Pulkki, Kallajoki, Heikkila, Laine, Mattila, Nieminen, Parvinen, Voipio-Pulkki
European Journal of Clinical Investigation 1999
MEKK1 suppresses oxidative stress-induced apoptosis of embryonic stem cell-derived cardiac myocytes
T Minamino, T Yujiri, PJ Papst, ED Chan, GL Johnson, N Terada
Proceedings of the National Academy of Sciences 1999
A possible involvement of ion transporter in tumor necrosis factor alpha and cycloheximide-induced apoptosis of endothelial cells
H Fujita, I Morita, S Murota
Mediators of Inflammation 1999
Postmitochondrial regulation of apoptosis during heart failure
JC Reed, G Paternostro
Proceedings of the National Academy of Sciences 1999
Quantitative assessment of cardiac myocyte apoptosis in tissue sections using the fluorescence-based tunel technique enhanced with counterstains
TM Scarabelli, RA Knight, NB Rayment, TJ Cooper, A Stephanou, BK Brar, KM Lawrence, G Santilli, DS Latchman, GF Baxter, DM Yellon
Journal of Immunological Methods 1999
Cardiotrophin-1 (CT-1): a novel hypertrophic and cardioprotective agent
DS Latchman
International Journal of Experimental Pathology 1999
Protection of the myocardial cell during ischemia
P Théroux
The American Journal of Cardiology 1999
Apoptosis in cardiac disease
TN James
The American Journal of Medicine 1999
Differential regulation of Bcl-2, AP-1 and NF-κB on cardiomyocyte apoptosis during myocardial ischemic stress adaptation
N Maulik, S Goswami, N Galang, DK Das
FEBS Letters 1999
Inhibition of p38 mitogen-activated protein kinase decreases cardiomyocyte apoptosis and improves cardiac function after myocardial ischemia and reperfusion
XL Ma, S Kumar, F Gao, CS Louden, BL Lopez, TA Christopher, C Wang, JC Lee, GZ Feuerstein, TL Yue
Circulation 1999
The mitochondrial apoptotic pathway is activated by serum and glucose deprivation in cardiac myocytes
S Bialik, VL Cryns, A Drincic, S Miyata, AL Wollowick, A Srinivasan, RN Kitsis
Circulation research 1999
Increased severity of viral myocarditis in mice lacking lymphocyte maturation
T Kanda, H Koike, M Arai, JE Wilson, CM Carthy, D Yang, BM McManus, R Nagai, I Kobayashi
International Journal of Cardiology 1999
Is apoptosis a mechanism of cell death of cardiomyocytes in chronic chagasic myocarditis?
MA Rossi, AC Souza
International Journal of Cardiology 1999
Brain death-induced myocardial dysfunction: a role for apoptosis?
M Kirsch, S Bertrand, L Lecerf, M Ginat, JP Garnier, D Loisance
Transplantation Proceedings 1999
Protective role of nitric oxide synthase against ischemia-reperfusion injury in guinea pig myocardial mitochondria
Y Hotta, H Otsuka-Murakami, M Fujita, J Nakagawa, M Yajima, W Liu, N Ishikawa, N Kawai, T Masumizu, M Kohno
European Journal of Pharmacology 1999
JNK activation and apoptosis during ischemia—reperfusion
I Onishi, K Shimizu, T Tani, T Hashimoto, K Miwa
Transplantation Proceedings 1999
Caspase Inhibition Reduces Myocyte Cell Death Induced by Myocardial Ischemia and Reperfusion In Vivo
TA Holly, A Drincic, Y Byun, S Nakamura, K Harris, FJ Klocke, VL Cryns
Journal of Molecular and Cellular Cardiology 1999
Apoptosis in skeletal myocytes of patients with chronic heart failure is associated with exercise intolerance
V Adams, H Jiang, J Yu, S Möbius-Winkler, E Fiehn, A Linke, C Weigl, G Schuler, R Hambrecht
Journal of the American College of Cardiology 1999
Oxidative Damage of Cardiomyocytes Is Limited by Extracellular Regulated Kinases 1/2-mediated Induction of Cyclooxygenase-2
SR Adderley, DJ Fitzgerald
The Journal of biological chemistry 1999
Glucose Uptake and Glycolysis Reduce Hypoxia-induced Apoptosis in Cultured Neonatal Rat Cardiac Myocytes
R Malhotra, FC Brosius
The Journal of biological chemistry 1999
Molecular Mechanisms of Myocardial Remodeling
B Swynghedauw
Physiological reviews 1999
Alterations in sarcoplasmic reticulum function and gene expression in ischemic-reperfused rat heart
RM Temsah, T Netticadan, D Chapman, S Takeda, S Mochizuki, NS Dhalla
American journal of physiology. Heart and circulatory physiology 1999
Contrast Medium- and Mannitol-Induced Apoptosis in Heart and Kidney of SHR Rats
J Zhang, CG Duarte, S Ellis
Toxicologic pathology 1999
Enhanced DNA fragmentation in the thymus of spontaneously hypertensive rats
H Suzuki, FA Delano, N Jamshidi, D Katz, M Mori, K Kosaki, RA Gottlieb, H Ishii, GW Schmid-Schönbein
American journal of physiology. Heart and circulatory physiology 1999
APOPTOSIS OF SINUSOIDAL ENDOTHELIAL CELLS OCCURS DURING LIVER PRESERVATION INJURY BY A CASPASE-DEPENDENT MECHANISM1:
S Natori, M Selzner, KL Valentino, LC Fritz, A Srinivasan, PA Clavien, GJ Gores
Transplantation 1999
Proapoptotic effects of ANG II in human coronary artery endothelial cells: role of AT 1 receptor and PKC activation
D Li, B Yang, MI Philips, JL Mehta
American journal of physiology. Heart and circulatory physiology 1999
Metallothionein-overexpressing neonatal mouse cardiomyocytes are resistant to H 2 O 2 toxicity
GW Wang, DA Schuschke, YJ Kang
American journal of physiology. Heart and circulatory physiology 1999
Reversal of permeability transition during recovery of hearts from ischemia and its enhancement by pyruvate
PM Kerr, MS Suleiman, AP Halestrap
American journal of physiology. Heart and circulatory physiology 1999
Nitric oxide triggers programmed cell death (apoptosis) of adult rat ventricular myocytes in culture
DJ Pinsky, W Aji, M Szabolcs, ES Athan, Y Liu, YM Yang, RP Kline, KE Olson, PJ Cannon
American journal of physiology. Heart and circulatory physiology 1999
Ischemic preconditioning attenuates apoptosis through protein kinase C in rat hearts
T Okamura, T Miura, H Iwamoto, K Shirakawa, S Kawamura, Y Ikeda, M Iwatate, M Matsuzaki
American journal of physiology. Heart and circulatory physiology 1999
Stress Adaptation, Prophylaxis and Treatment
DK Das
1999
Cardiac Fatty Acid Metabolism and the Induction of Apoptosis:
GC Sparagna, DL Hickson-Bick
The American Journal of the Medical Sciences 1999
A caspase inhibitor fully protects rats against lethal normothermic liver ischemia by inhibition of liver apoptosis
R Cursio, J Gugenheim, JE Ricci, D Crenesse, P Rostagno, L Maulon, MC Saint-Paul, B Ferrua, P Auberger
The FASEB Journal 1999
ENDOTHELIAL CELL AND HEPATOCYTE DEATHS OCCUR BY APOPTOSIS AFTER ISCHEMIA-REPERFUSION INJURY IN THE RAT LIVER1,2:
V Kohli, M Selzner, JF Madden, RC Bentley, PA Clavien
Transplantation 1999
Resuscitation with Lactated Ringer's Solution in Rats with Hemorrhagic Shock Induces Immediate Apoptosis:
S Deb, B Martin, L Sun, P Ruff, D Burris, N Rich, S DeBreux, B Austin, P Rhee
The Journal of Trauma: Injury, Infection and Critical Care 1999
Profound Apoptosis-Mediated Regional Myocyte Loss and Compensatory Hypertrophy in Pigs With Hibernating Myocardium
H Lim, JA Fallavollita, R Hard, CW Kerr, JM Canty
Circulation 1999
Signaling Pathways in Reactive Oxygen Species–Induced Cardiomyocyte Apoptosis
R von Harsdorf, PF Li, R Dietz
Circulation 1999
Activation of Mitochondrial K ATP Channel Elicits Late Preconditioning Against Myocardial Infarction via Protein Kinase C Signaling Pathway
E Takashi, Y Wang, M Ashraf
Circulation research 1999
ARC Inhibits Cytochrome c Release From Mitochondria and Protects Against Hypoxia-Induced Apoptosis in Heart-Derived H9c2 Cells
D Ekhterae, Z Lin, MS Lundberg, MT Crow, FC Brosius, G Núñez
Circulation research 1999
Molecular Cardiology in Clinical Practice
M Sanders, JB Kostis
1999
Studies of Aging
H Sternberg, PS Timiras
1999
Myocardial preconditioning: basic concepts and potential mechanisms
S Okubo, L Xi, N L Bernardo, K Yoshida, R C Kukreja
Molecular and Cellular Biochemistry 1999
Insulin-Like Growth Factor I: An Attractive Option for Chronic Heart Failure?
MY Donath, J Zapf
Drugs & Aging 1999
Apoptosis in insulin-secreting cells. Evidence for the role of intracellular Ca2+ stores and arachidonic acid metabolism
YP Zhou, D Teng, F Dralyuk, D Ostrega, MW Roe, L Philipson, KS Polonsky
Journal of Clinical Investigation 1998
Enhanced expression of p53 and apoptosis induced by blockade of the vacuolar proton ATPase in cardiomyocytes
X Long, MT Crow, SJ Sollott, L O'Neill, DS Menees, ML Hipolito, MO Boluyt, T Asai, EG Lakatta
Journal of Clinical Investigation 1998
Complement activation and regulator expression after anoxic injury of human endothelial cells
A Väkevä, S Meri
APMIS 1998
Calpain mediates ischemic injury of the liver through modulation of apoptosis and necrosis
V Kohli, JF Madden, RC Bentley, PA Clavien
Gastroenterology 1998
Myocardial dna strand breaks are detected in biopsy tissues from patients with dilated cardiomyopathy
Y Seki, H Kai, M Kai, A Muraishi, K Adachi, T Imaizumi
Clinical Cardiology 1998
The role of mitochondria in the salvage and the injury of the ischemic myocardium
FD Lisa, R Menabò, M Canton, V Petronilli
Biochimica et Biophysica Acta (BBA) - Bioenergetics 1998
Role of enhanced ceramide generation in DNA damage and cell death in chemical hypoxic injury to LLC-PK1 cells
N Ueda, GP Kaushal, X Hong, SV Shah
Kidney International 1998
Role of nitric oxide in the control of apoptosis in the microvasculature
A López-Farré, JA Rodrı́guez-Feo, LS de Miguel, L Rico, S Casado
The International Journal of Biochemistry & Cell Biology 1998
Neurohormonal Activation, Oxygen Free Radicals, and Apoptosis in the Pathogenesis of Congestive Heart Failure
RR Ruffolo, GZ Feuerstein
Journal of Cardiovascular Pharmacology 1998
CNI-1493 Prolongs Survival and Reduces Myocyte Loss, Apoptosis, and Inflammation During Rat Cardiac Allograft Rejection
X Yang, M Szabolcs, O Minanov, N &NA;, RR Sciacca, M Bianchi, KJ Tracey, RE Michler, PJ Cannon
Journal of Cardiovascular Pharmacology 1998
Increased Circulating Soluble Form of Fas in Patients With Dilated Cardiomyopathy
H Kawakami, Y Shigematsu, T Ohtsuka, H Okayama, Y Hayashi, Y Hara, K Kodama, M Hamada, K Hiwada
Japanese Circulation Journal 1998
Initiation of apoptosis in hepatocytes during prolonged arterial hypotension and postresuscitation period
NV Nosova, VL Kozhura, IS Novoderzhkina
Bulletin of Experimental Biology and Medicine 1998
Elucidating the molecular mechanism of the permeability transition pore and its role in reperfusion injury of the heart
AP Halestrap, PM Kerr, S Javadov, KY Woodfield
Biochimica et Biophysica Acta (BBA) - Bioenergetics 1998
Randomised, double-blind, placebo-controlled trial of human recombinant growth hormone in patients with chronic heart failure due to dilated cardiomyopathy
KJ Osterziel, O Strohm, J Schuler, M Friedrich, D Hänlein, R Willenbrock, SD Anker, PA Poole-Wilson, MB Ranke, R Dietz
The Lancet 1998
Apoptosis of endothelial cells is associated with paracrine induction of adhesion molecules: evidence for an interleukin-1beta-dependent paracrine loop
MJ Hébert, SR Gullans, HS Mackenzie, HR Brady
The American Journal of Pathology 1998
Hibernating Myocardium
FH Epstein, W Wijns, SF Vatner, PG Camici
New England Journal of Medicine 1998
Coronary artery constriction in rats: necrotic and apoptotic myocyte death
J Kajstura, Y Liu, A Baldini, B Li, G Olivetti, A Leri, P Anversa
The American Journal of Cardiology 1998
VENTRICULAR REMODELING
S Goldstein, AS Ali, H Sabbah
Cardiology Clinics 1998
Induction of Apoptosis in Cardiac Myocytes by an A3Adenosine Receptor Agonist
V Shneyvays, H Nawrath, KA Jacobson, A Shainberg
Experimental Cell Research 1998
Ischemia–Reperfusion-Induced Apoptosis and p53 Expression in the Course of Rat Heterotopic Heart Transplantation
L Formigli, L Ibba-Manneschi, AM Perna, C Nediani, P Liguori, A Tani, S Zecchi-Orlandini
Microvascular Research 1998
Delayed activation-induced T lymphocytes death in aplastic anemia: related with abnormal Fas system
S C Kim, Y H Min, S Lee, S Y Chung, N C Yoo, J W Lee, J S Hahn, Y W Ko
The Korean Journal of Internal Medicine 1998
Pyruvate prevents hydrogen peroxide-induced apoptosis
N Ramakrishnan, R Chen, DE McClain, R Bünger
Free Radical Research 1998
"Apoptotic" Myocytes in Infarct Area in Rabbit Hearts May Be Oncotic Myocytes With DNA Fragmentation : Analysis by Immunogold Electron Microscopy Combined With In Situ Nick End-Labeling
M Ohno, G Takemura, A Ohno, J Misao, Y Hayakawa, S Minatoguchi, T Fujiwara, H Fujiwara
Kidney International 1998
Tumor necrosis factor in the heart
DR Meldrum
American Journal of Physiology - Regulatory, Integrative and Comparative Physiology 1998
Myocardial angiotensin II receptor expression and ischemia-reperfusion injury
B Yang, D Li, MI Phillips, P Mehta, JL Mehta
Vascular medicine (London, England) 1998
Bcl-2 and Bax expression in adult rat hearts after coronary occlusion: age-associated differences
L Liu, G Azhar, W Gao, X Zhang, JY Wei
American Journal of Physiology - Regulatory, Integrative and Comparative Physiology 1998
Ox-LDL induces apoptosis in human coronary artery endothelial cells: role of PKC, PTK, bcl-2, and Fas
D Li, B Yang, JL Mehta
American journal of physiology. Heart and circulatory physiology 1998
Identification of gene family of caspases in rat kidney and altered expression in ischemia-reperfusion injury
GP Kaushal, AB Singh, SV Shah
American journal of physiology. Renal physiology 1998
MKK6 Activates Myocardial Cell NF-κB and Inhibits Apoptosis in a p38 Mitogen-activated Protein Kinase-dependent Manner
D Zechner, R Craig, DS Hanford, PM McDonough, RA Sabbadini, CC Glembotski
The Journal of biological chemistry 1998
β-Adrenergic stimulation causes cardiocyte apoptosis: influence of tachycardia and hypertrophy
Y Shizukuda, PM Buttrick, DL Geenen, AC Borczuk, RN Kitsis, EH Sonnenblick
American journal of physiology. Heart and circulatory physiology 1998
Effects of ACE inhibition on cardiomyocyte apoptosis in dogs with heart failure
A Goussev, VG Sharov, H Shimoyama, M Tanimura, M Lesch, S Goldstein, HN Sabbah
American journal of physiology. Heart and circulatory physiology 1998
Apoptosis of sinusoidal endothelial cells is a critical mechanism of preservation injury in rat liver transplantation
W Gao, RC Bentley, JF Madden, PA Clavien
Hepatology 1998
Myocardial Infarction and Apoptosis After Myocardial Ischemia and Reperfusion : Role of the Terminal Complement Components and Inhibition by Anti-C5 Therapy
AP Vakeva, A Agah, SA Rollins, LA Matis, L Li, GL Stahl
Circulation 1998
APOPTOSIS AND INCREASED EXPRESSION OF INDUCIBLE NITRIC OXIDE SYNTHASE IN HUMAN ALLOGRAFT REJECTION1:
MJ Szabolcs, S Ravalli, O Minanov, RR Sciacca, RE Michler, PJ Cannon
Transplantation 1998
APOPTOSIS IN ISCHEMIA/REPERFUSION INJURY OF HUMAN RENAL ALLOGRAFTS1:
AT Burns, DR Davies, AJ Mclaren, L Cerundolo, PJ Morris, SV Fuggle
Transplantation 1998
Myocyte Cell Death in the Diseased Heart
P Anversa, J Kajstura
Circulation research 1998
Apoptosis: Basic Mechanisms and Implications for Cardiovascular Disease
A Haunstetter, S Izumo
Circulation research 1998
Effect of Vacuolar Proton ATPase on pH i , Ca 2+ , and Apoptosis in Neonatal Cardiomyocytes During Metabolic Inhibition/Recovery
E Karwatowska-Prokopczuk, JA Nordberg, HL Li, RL Engler, RA Gottlieb
Circulation research 1998
Role of Apoptosis in the Disappearance of Infiltrated and Proliferated Interstitial Cells After Myocardial Infarction
G Takemura, M Ohno, Y Hayakawa, J Misao, M Kanoh, A Ohno, Y Uno, S Minatoguchi, T Fujiwara, H Fujiwara
Circulation research 1998
Chronic Heart Failure in the United States: A Manifestation of Coronary Artery Disease
M Gheorghiade, RO Bonow
Circulation 1998
Possible Involvement of Stress-Activated Protein Kinase Signaling Pathway and Fas Receptor Expression in Prevention of Ischemia/Reperfusion-Induced Cardiomyocyte Apoptosis by Carvedilol
TL Yue, XL Ma, X Wang, AM Romanic, G Liu, C Louden, JL Gu, S Kumar, G Poste, RR Ruffolo, GZ Feuerstein
Circulation research 1998
Modes of Myocardial Cell Injury and Cell Death in Ischemic Heart Disease
LM Buja, ML Entman
Circulation 1998
Protection Against Ischemia/Reperfusion Damage of the Heart
Y Abiko, M Karmazyn
1998
Unstable Coronary Artery Syndromes Pathophysiology, Diagnosis and Treatment
RL Wilensky
1998
Free Radicals, Oxidative Stress, and Antioxidants
T Özben
1998
Arrhythmogenic right ventricular dysplasia/cardiomyopathy: Review for the clinician
K Ananthasubramaniam, F Khaja
Progress in Cardiovascular Diseases 1998
Apoptosis in heart failure
HN Sabbah, VG Sharov
Progress in Cardiovascular Diseases 1998
Myocardial Damage
JC Kaski, DW Holt
1998
Myocardial Ischemia and Reperfusion
MV Cohen, RJ Gelpi, JM Downey, J Slezak
1998
Dedifferentiated cardiomyocytes from chronic hibernating myocardium are ischemia-tolerant
J Ausma, F Thoné, G D Dispersyn, W Flameng, J L Vanoverschelde, F C Ramaekers, M Borgers
Molecular and Cellular Biochemistry 1998
Ischemic preconditioning attenuates apoptotic cell death associated with ischemia/reperfusion
N Maulik, T Yoshida, R M Engelman, D Deaton, J E Flack 3rd, J A Rousou, D K Das
Molecular and Cellular Biochemistry 1998
Chemical hypoxia triggers apoptosis of cultured neonatal rat cardiac myocytes: modulation by calcium-regulated proteases and protein kinases
S J Chen, M E Bradley, T C Lee
Molecular and Cellular Biochemistry 1998
p53 and the hypoxia-induced apoptosis of cultured neonatal rat cardiac myocytes
X Long, MO Boluyt, ML Hipolito, MS Lundberg, JS Zheng, L O'Neill, C Cirielli, EG Lakatta, MT Crow
Journal of Clinical Investigation 1997
Myocyte apoptosis during acute myocardial infarction in the mouse localizes to hypoxic regions but occurs independently of p53
S Bialik, DL Geenen, IE Sasson, R Cheng, JW Horner, SM Evans, EM Lord, CJ Koch, RN Kitsis
Journal of Clinical Investigation 1997
Oxidative stress activates extracellular signal-regulated kinases through Src and Ras in cultured cardiac myocytes of neonatal rats
R Aikawa, I Komuro, T Yamazaki, Y Zou, S Kudoh, M Tanaka, I Shiojima, Y Hiroi, Y Yazaki
Journal of Clinical Investigation 1997
Overexpression of insulin-like growth factor-1 in mice protects from myocyte death after infarction, attenuating ventricular dilation, wall stress, and cardiac hypertrophy
Q Li, B Li, X Wang, A Leri, KP Jana, Y Liu, J Kajstura, R Baserga, P Anversa
Journal of Clinical Investigation 1997
Role of caspases (ICE/CED 3 proteases) in DNA damage and cell death in response to a mitochondrial inhibitor, antimycin A Rapid Communication
GP Kaushal, N Ueda, SV Shah
Kidney International 1997
Tyrosine phosphorylation in DNA damage and cell death in hypoxic injury to LLC-PK1 cells
H Hagar, N Ueda, SV Shah
Kidney International 1997
Apoptosis in aorta of deoxycorticosterone acetate-salt hypertensive rats
AM Sharifi, EL Schiffrin
Journal of Hypertension 1997
Plasma Fas Ligand, an Inducer of Apoptosis, and Plasma Soluble Fas, an Inhibitor of Apoptosis, in Patients With Chronic Congestive Heart Failure
K Nishigaki, S Minatoguchi, M Seishima, K Asano, T Noda, N Yasuda, H Sano, H Kumada, M Takemura, A Noma, T Tanaka, S Watanabe, H Fujiwara
Journal of the American College of Cardiology 1997
Anabolic steroids induce injury and apoptosis of differentiated skeletal muscle
S Abu-Shakra, MS Alhalabi, FC Nachtman, RA Schemidt, WS Brusilow
Journal of Neuroscience Research 1997
Induction of early immediate genes and programmed cell death following cardioplegic arrest in human hearts
H Aebert
European Journal of Cardio-Thoracic Surgery 1997
Cytokines and Cardiomyocyte Death
KJ Pulkki
Annals of Medicine 1997
Ceramide is involved in triggering of cardiomyocyte apoptosis induced by ischemia and reperfusion
AE Bielawska, JP Shapiro, L Jiang, HS Melkonyan, C Piot, CL Wolfe, LD Tomei, YA Hannun, SR Umansky
The American Journal of Pathology 1997
Apoptosis in cardiovascular disease
MJ Davies
Heart (British Cardiac Society) 1997
Alternative Splicing of the Primary Fas Transcript Generating Soluble Fas Antagonists Is Suppressed in the Failing Human Ventricular Myocardium
H Schumann, H Morawietz, K Hakim, HR Zerkowski, T Eschenhagen, J Holtz, D Darmer
Biochemical and Biophysical Research Communications 1997
Apoptosis in the Failing Human Heart
G Olivetti, R Abbi, F Quaini, J Kajstura, W Cheng, JA Nitahara, E Quaini, CD Loreto, CA Beltrami, S Krajewski, JC Reed, P Anversa
New England Journal of Medicine 1997
Ischemia–Reperfusion Injury on the Pancreas in Rats: Identification of Acinar Cell Apoptosis
K Fujimoto, R Hosotani, M Wada, JU Lee, T Koshiba, Y Miyamoto, R Doi, M Imamura
Journal of Surgical Research 1997
Molecular and Cellular Mechanisms of Myocardial Failure
WS MD
The American Journal of Cardiology 1997
Protective Effects of Carvedilol in the Myocardium
GZ MD, AB PhD, RR PhD
The American Journal of Cardiology 1997
A novel mechanism of JNK1 activation. Nuclear translocation and activation of JNK1 during ischemia and reperfusion
Y Mizukami, K Yoshioka, S Morimoto, K Yoshida
The Journal of biological chemistry 1997
Autoimmunity in Myocarditis: Relevance of Animal Models
SA Huber
Clinical Immunology and Immunopathology 1997
Apoptosis of skeletal and cardiac muscles and physical exercise
U Carraro, C Franceschi
Aging clinical and experimental research 1997
Complex causes of fatal myocardial infarction
TN James
Fibrinolysis and Proteolysis 1997
Early apoptosis in human myocardial infarcts
JP Veinot, DA Gattinger, H Fliss
Human Pathology 1997
Angiotensin II Activates Programmed Myocyte Cell Deathin Vitro
E Cigola, J Kajstura, B Li, LG Meggs, P Anversa
Experimental Cell Research 1997
Myocardial cell death and apoptosis in hibernating myocardium
C Chen, L Ma, D R Linfert, T Lai, J T Fallon, L D Gillam, D D Waters, G J Tsongalis
Journal of the American College of Cardiology 1997
Nuclear translocation of PKC zeta during ischemia and its inhibition by wortmannin, an inhibitor of phosphatidylinositol 3-kinase
Y Mizukami, T Hirata, K Yoshida
FEBS Letters 1997
Biology of acute renal failure: Therapeutic implications
W Lieberthal
Kidney International 1997
Apoptosis and Congestive Heart Failure
G Feuerstein, RR Ruffolo, TL Yue
Trends in Cardiovascular Medicine 1997
Tissue-specific Pattern of Stress Kinase Activation in Ischemic/Reperfused Heart and Kidney
T Yin, G Sandhu, CD Wolfgang, A Burrier, RL Webb, DF Rigel, T Hai, J Whelan
The Journal of biological chemistry 1997
Atrial Natriuretic Peptide Induces Apoptosis in Neonatal Rat Cardiac Myocytes
CF Wu, NH Bishopric, RE Pratt
The Journal of biological chemistry 1997
ANTIAPOPTOTIC COMPOUND TO ENHANCE HYPOTHERMIC LIVER PRESERVATION1:
G Wu, LD Tomei, IC Bathurst, F Zhang, CB Hong, CJ Issel, A Columbano, RK Salley, S Chien
Transplantation 1997
Complex Causes of Fatal Myocardial Infarction
TN James
Circulation 1997
The bcl-2 Gene Product Prevents Programmed Cell Death of Ventricular Myocytes
LA Kirshenbaum, D de Moissac
Circulation 1997
Ischemic Preconditioning Decreases Apoptosis in Rat Hearts In Vivo
CA Piot, D Padmanaban, PC Ursell, RE Sievers, CL Wolfe
Circulation 1997
Death by Design: Programmed Cell Death in Cardiovascular Biology and Disease
WR MacLellan, MD Schneider
Circulation research 1997
Altered Balance Between Cell Replication and Apoptosis in Hearts and Kidneys of Newborn SHR
P Moreau, BS Tea, TV Dam, P Hamet
Hypertension 1997
Adenosine, Cardioprotection and Its Clinical Application
RM Mentzer, M Kitakaze, JM Downey, M Hori
1997
DNA Scission After Focal Brain Ischemia: Temporal Differences in Two Species
M Tagaya, KF Liu, B Copeland, D Seiffert, R Engler, JH Garcia, GJ del Zoppo
Stroke; a journal of cerebral circulation 1997
Cell Death Suggestive of Apoptosis After Spinal Cord Ischemia in Rabbits
ME Mackey, Y Wu, R Hu, JA DeMaro, MF Jacquin, GK Kanellopoulos, CY Hsu, NT Kouchoukos
Stroke; a journal of cerebral circulation 1997
Rapid Disruption of an Astrocyte Interaction With the Extracellular Matrix Mediated by Integrin α 6 β 4 During Focal Cerebral Ischemia/Reperfusion
S Wagner, M Tagaya, JA Koziol, V Quaranta, GJ del Zoppo
Stroke; a journal of cerebral circulation 1997
Reactive Oxygen Species and Platelet Activation in Reperfusion Injury
RC Forde, DJ Fitzgerald
Circulation 1997
Hypoxia/Reoxygenation Stimulates Jun Kinase Activity Through Redox Signaling in Cardiac Myocytes
KR Laderoute, KA Webster
Circulation research 1997
Cardiomyocyte Apoptosis and Cardiac Angiotensin-Converting Enzyme in Spontaneously Hypertensive Rats
J Díez, A Panizo, M Hernández, F Vega, I Sola, MA Fortuño, J Pardo
Hypertension 1997
Life and Death in the Cardiovascular System
ET Yeh
Circulation 1997
Apoptosis in Human Acute Myocardial Infarction
A Saraste, K Pulkki, M Kallajoki, K Henriksen, M Parvinen, LM Voipio-Pulkki
Circulation 1997
Immunohistochemical study on tissue transglutaminase and copper-zinc superoxide dismutase in human myocardium: Its relevance to apoptosis detected by the nick end labelling method
K Kashima, S Yokoyama, T Daa, I Nakayama, T Iwaki
Virchows Archiv 1997
Textbook of Coronary Thrombosis and Thrombolysis
RC Becker
1997
Pathobiology and Clinical Impact of Reperfusion Injury
Birnbaum, Leor, Kloner
Journal of Thrombosis and Thrombolysis 1997
Myocardial Reperfusion Injury: From Bench to Bedside
Horrigan, Nicolini
Journal of Thrombosis and Thrombolysis 1997
Lethal Reperfusion Injury: Does Anyone Still Care?
Mullane
Journal of Thrombosis and Thrombolysis 1997
Apoptosis: A New Mechanism of Lethal Myocardial "Reperfusion Injury"?
Piot, Wolfe
Journal of Thrombosis and Thrombolysis 1997
Lethal Myocardial Reperfusion Injury: Fact or Fiction?
Werns
Journal of Thrombosis and Thrombolysis 1997
Myocardial Reperfusion Injury
Becker
Journal of Thrombosis and Thrombolysis 1997
Expression of p21(WAF1/CIP1/SDI1) and p53 in apoptotic cells in the adrenal cortex and induction by ischemia/reperfusion injury
VV Didenko, X Wang, L Yang, PJ Hornsby
Journal of Clinical Investigation 1996
Preconditioning rabbit cardiomyocytes: role of pH, vacuolar proton ATPase, and apoptosis
RA Gottlieb, DL Gruol, JY Zhu, RL Engler
Journal of Clinical Investigation 1996
Apoptosis in pressure overload-induced heart hypertrophy in the rat
E Teiger, VD Than, L Richard, C Wisnewsky, BS Tea, L Gaboury, J Tremblay, K Schwartz, P Hamet
Journal of Clinical Investigation 1996
Tumor necrosis factor alpha-induced apoptosis in cardiac myocytes. Involvement of the sphingolipid signaling cascade in cardiac cell death
KA Krown, MT Page, C Nguyen, D Zechner, V Gutierrez, KL Comstock, CC Glembotski, PJ Quintana, RA Sabbadini
Journal of Clinical Investigation 1996
Myocardial infarction as a problem of growth control:Cell cycle therapy for cardiac myocytes?
MD Schneider
Journal of Cardiac Failure 1996
Apoptosis — Molecular mechanisms and biomedical implications
DJ McConkey, B Zhivotovsky, S Orrenius
Molecular Aspects of Medicine 1996
Modulation of radiation-induced apoptosis by lazaroids
N Neamati, DW Voehringer, MD Story, RE Meyn
Radiation Oncology Investigations 1996
Methods for studying experimental myocardial ischemic and reperfusion injury
SC Black, IW Rodger
Journal of Pharmacological and Toxicological Methods 1996
Induction of apoptosis in myocardial infarction and its possible relationship to nitric oxide synthase in macrophages
H Suzuki, SM Wildhirt, RR Dudek, KS Narayan, AH Bailey, RJ Bing
Tissue and Cell 1996
Monthly Update Cardiovascular & Renal: Apoptosis in cardiac health and disease
GZ Feuerstein, TL Yue
Expert Opinion on Investigational Drugs 1996
Biochemical Mechanisms in Heart Function
EG Krause, R Vetter
1996
Apoptosis in Ischemic and Reperfused Rat Myocardium
H Fliss, D Gattinger
Circulation research 1996
High and Low Molecular Weight Fibroblast Growth Factor-2 Increase Proliferation of Neonatal Rat Cardiac Myocytes but Have Differential Effects on Binucleation and Nuclear Morphology: Evidence for Both Paracrine and Intracrine Actions of Fibroblast Growth Factor-2
KB Pasumarthi, E Kardami, PA Cattini
Circulation research 1996
E-Selectin Appears in Nonischemic Tissue During Experimental Focal Cerebral Ischemia
HP Haring, EL Berg, N Tsurushita, M Tagaya, GJ del Zoppo
Stroke; a journal of cerebral circulation 1996
Apoptosis of Cardiac Myocytes During Cardiac Allograft Rejection: Relation to Induction of Nitric Oxide Synthase
M Szabolcs, RE Michler, X Yang, W Aji, D Roy, E Athan, RR Sciacca, OP Minanov, PJ Cannon
Circulation 1996
Expression of bcl-2 Protein, an Inhibitor of Apoptosis, and Bax, an Accelerator of Apoptosis, in Ventricular Myocytes of Human Hearts With Myocardial Infarction
J Misao, Y Hayakawa, M Ohno, S Kato, T Fujiwara, H Fujiwara
Circulation 1996
Cardiomyocyte Troponin T Immunoreactivity Is Modified by Cross-linking Resulting From Intracellular Calcium Overload
L Gorza, R Menabò, M Vitadello, CM Bergamini, FD Lisa
Circulation 1996
Biochemical Regulation of Myocardium
R Vetter, EG Krause
1996
Myocardial Ischemia: Mechanisms, Reperfusion, Protection
M Karmazyn
1996
Myocardial infarction and nitric oxide
RJ Bing, H Suzuki
Molecular and Cellular Biochemistry 1996
Apoptosis in the heart: when and why?
HJ Brmme, J Holtz
Molecular and Cellular Biochemistry 1996
Apoptosis in rheumatoid arthritis synovium
GS Firestein, M Yeo, NJ Zvaifler
Journal of Clinical Investigation 1995
Stretch-induced programmed myocyte cell death
W Cheng, B Li, J Kajstura, P Li, MS Wolin, EH Sonnenblick, TH Hintze, G Olivetti, P Anversa
Journal of Clinical Investigation 1995
Caspase Inhibitors and Myocardial Apoptosis
Y Li, R Cohen
International Anesthesiology Clinics
Magnetic resonance imaging of cardiomyocyte apoptosis with a novel magneto-optical nanoparticle
DE Sosnovik, EA Schellenberger, M Nahrendorf, MS Novikov, T Matsui, G Dai, F Reynolds, L Grazette, A Rosenzweig, R Weissleder, L Josephson
Magnetic Resonance in Medicine 2005
Cytoprotective Effect of 3-[2-[4-(3-Chloro-2-methylphenyl)-1-piperazinyl]ethyl]-5,6-dimethoxy-1-(4-imidazolylmethyl)-1H-indazole Dihydrochloride 3.5 Hydrate (DY-9760e) Against Ischemia/Reperfusion-Induced Injury in Rat Heart Involves Inhibition of Fodrin Breakdown and Protein Tyrosine Nitration
M Hashimoto, Y Takada, Y Takeuchi, J Kasahara, H Hisa, Y Shirasaki, K Fukunaga
Journal of Pharmacological Sciences 2005
In situ detection of apoptosis in regressing corpus luteum of pregnant sow: Evidence of an early presence of DNA fragmentation*1
M Bacci
Domestic Animal Endocrinology 1996
Molecular and clinical aspects of apoptosis
AG Uren, DL Vaux
Pharmacology & Therapeutics 1996
Apoptosis in the heart: when and why?
HJ Br�mme, J Holtz
Molecular and Cellular Biochemistry 1996
Physical and functional sensitivity of zinc finger transcription factors to redox change
X Wu, NH Bishopric, DJ Discher, BJ Murphy, KA Webster
Molecular and cellular biology 1996
In situ apoptosis assay for the detection of early acute myocardial infarction
RH Bardales, LS Hailey, SS Xie, RF Schaefer, SM Hsu
The American Journal of Pathology 1996
Evidence of cardiocyte apoptosis in myocardium of dogs with chronic heart failure
VG Sharov, HN Sabbah, H Shimoyama, AV Goussev, M Lesch, S Goldstein
The American Journal of Pathology 1996
Apoptosis — the cell's silent exit
PR Bär
Life Sciences 1996
Evidence of Apoptosis in Arrhythmogenic Right Ventricular Dysplasia
Z Mallat, A Tedgui, F Fontaliran, R Frank, M Durigon, G Fontaine
New England Journal of Medicine 1996
Apoptosis in Myocytes in End-Stage Heart Failure
J Narula, N Haider, R Virmani, TG DiSalvo, FD Kolodgie, RJ Hajjar, U Schmidt, MJ Semigran, GW Dec, BA Khaw
New England Journal of Medicine 1996
Apoptosis in the Heart
WS Colucci
New England Journal of Medicine 1996
Death by any other name
SM Schwartz, MR Bennett
The American Journal of Pathology 1995
Cardioprotective effect of insulin-like growth factor I in myocardial ischemia followed by reperfusion
M Buerke, T Murohara, C Skurk, C Nuss, K Tomaselli, AM Lefer
Proceedings of the National Academy of Sciences 1995
Gender differences and aging: Effects on the human heart
G Olivetti, G Giordano, D Corradi, M Melissari, C Lagrasta, SR Gambert, P Anversa
Journal of the American College of Cardiology 1995
Apoptosis, DNA damage and ubiquitin expression in normal and mdx muscle fibers after exercise
M Sandri, U Carraro, M Podhorska-Okolov, C Rizzi, P Arslan, D Monti, C Franceschi
FEBS Letters 1995
The role of complement in intestinal ischaemia and reperfusion injury
SA Gibbs, MR Weiser, HB Hechtman
Clinical Intensive Care 1995
Apoptosis in the pathogenesis and treatment of disease
CB Thompson
Science 1995
Involvement of inducible nitric oxide synthase in the inflammatory process of myocardial infarction
SM Wildhirt, RR Dudek, H Suzuki, RJ Bing
International Journal of Cardiology 1995
Antioxidants and Cardiovascular Disease
KR Bruckdorfer
1995
The cardiac cell cycle, pocket proteins, and p300
LA Kirshenbaum, MD Schneider
Trends in Cardiovascular Medicine 1995
Modulation of apoptosis by the widely distributed Bcl-2 homologue Bak
MC Kiefer, MJ Brauer, VC Powers, JJ Wu, SR Umansky, LD Tomei, PJ Barr
Nature 1995
Apoptosis in Human Atherosclerosis and Restenosis
JM Isner, M Kearney, S Bortman, J Passeri
Circulation 1995
The Cellular Basis of Pacing-Induced Dilated Cardiomyopathy: Myocyte Cell Loss and Myocyte Cellular Reactive Hypertrophy
J Kajstura, X Zhang, Y Liu, E Szoke, W Cheng, G Olivetti, TH Hintze, P Anversa
Circulation 1995
Infarct Salvage With Liposomal Prostaglandin E 1 Administered by Intravenous Bolus Immediately Before Reperfusion in a Canine Infarction-Reperfusion Model
RW Smalling, S Feld, N Ramanna, J Amirian, P Felli, WK Vaughn, C Swenson, A Janoff
Circulation 1995
Pathobiology and Clinical Impact of Reperfusion Injury
Birnbaum, Leor, Kloner
Journal of Thrombosis and Thrombolysis 1995
Advances in Pharmacology
B Drenger, Y Ginosar, Y Gozal
Advances in Pharmacology 1994
Hemodynamic actions of insulin
R Aikawa, M Nawano, Y Gu, H Katagiri, T Asano, W Zhu, R Nagai, I Komuro
The American journal of physiology 1994
Advances in Virus Research
LA Babiuk, MJ Lawman, HB Ohmann
Advances in virus research 1988
Current Topics in Cellular Regulation
G Cahill, T Aoki, R Smith
Current Topics in Cellular Regulation 1981
Myocardial Ischemia
LD Hillis, E Braunwald
New England Journal of Medicine 1977

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