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Citations to this article

Modulation of in vitro erythropoiesis. The influence of beta-adrenergic agonists on erythroid colony formation.
J E Brown, J W Adamson
J E Brown, J W Adamson
Published July 1, 1977
Citation Information: J Clin Invest. 1977;60(1):70-77. https://doi.org/10.1172/JCI108771.
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Research Article

Modulation of in vitro erythropoiesis. The influence of beta-adrenergic agonists on erythroid colony formation.

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Abstract

Canine marrow erythroid colony growth is enhanced by agents linked to the adenyl cyclase/cyclic AMP (cAMP) system, including cAMP, a phosphodieterase inhibitor (RO-20-1724), cholera enterotoxin, and beta-adrenergic agonists. The adrenergic effect is mediated by receptors having beta2-subspecificity. These receptors are distinct from putative receptors for erythropoietin and those acted upon by cholera enterotoxin. In addition, the population of cells most responsive to beta-agonists is distinct from the majority of erythropoientin-responsive cells, perhaps representing a subpopulation of this class of cell. This demonstration of an adenyl cyclase-linked mechanism regulating mammalian erythroid colony growth provides a model for the modulation by other hormones or small molecules of in vitro and, perhaps, in vivo erythropoiesis.

Authors

J E Brown, J W Adamson

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Total citations by year

Year: 2025 2024 2022 2021 2020 2015 2013 2012 2011 2010 2009 2006 2005 2004 2000 1996 1993 1992 1990 1988 1987 1986 1985 1984 1983 1981 1980 1979 1978 1977 Total
Citations: 1 1 1 1 1 2 3 1 3 2 2 1 1 1 1 1 1 1 2 2 1 2 2 1 4 2 3 4 6 2 56
Citation information
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Adrenergic modulation of erythropoiesis following severe injury is mediated through bone marrow stroma
RB Fonseca, AM Mohr, L Wang, E Clinton, ZC Sifri, P Rameshwar, DH Livingston
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Molecular Biology of Hematopoiesis 5
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