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Usage Information

Dengue: defining protective versus pathologic immunity
Alan L. Rothman
Alan L. Rothman
Published April 1, 2004
Citation Information: J Clin Invest. 2004;113(7):946-951. https://doi.org/10.1172/JCI21512.
View: Text | PDF
Review Series

Dengue: defining protective versus pathologic immunity

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Abstract

Dengue is an expanding public health problem, and an effective vaccine remains elusive. This review discusses how the significant influence of sequential infection with different dengue virus serotypes on the severity of disease can be viewed in terms of beneficial and detrimental effects of heterologous immunity. A more complete understanding of these effects is likely to be critical for predicting optimal vaccine-induced immune responses.

Authors

Alan L. Rothman

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Usage data is cumulative from May 2024 through May 2025.

Usage JCI PMC
Text version 786 401
PDF 130 51
Figure 172 7
Table 91 0
Citation downloads 75 0
Totals 1,254 459
Total Views 1,713
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Usage information is collected from two different sources: this site (JCI) and Pubmed Central (PMC). JCI information (compiled daily) shows human readership based on methods we employ to screen out robotic usage. PMC information (aggregated monthly) is also similarly screened of robotic usage.

Various methods are used to distinguish robotic usage. For example, Google automatically scans articles to add to its search index and identifies itself as robotic; other services might not clearly identify themselves as robotic, or they are new or unknown as robotic. Because this activity can be misinterpreted as human readership, data may be re-processed periodically to reflect an improved understanding of robotic activity. Because of these factors, readers should consider usage information illustrative but subject to change.

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