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Roderick J. Phillips, … , Michael P. Keane, Robert M. Strieter
Published August 1, 2004
Citation Information: J Clin Invest. 2004;114(3):438-446. https://doi.org/10.1172/JCI20997.
Citation Information: J Clin Invest. 2004;114(3):438-446. https://doi.org/10.1172/JCI20997.
Abstract
Previous reports have identified a circulating pool of CD45+ collagen I+ CXCR4+ (CD45+Col I+CXCR4+) cells, termed fibrocytes, that traffic to areas of fibrosis. No studies have demonstrated that these cells actually contribute to fibrosis, however. Pulmonary fibrosis was originally thought to be mediated solely by resident lung fibroblasts. Here we show that a population of human CD45+Col I+CXCR4+ circulating fibrocytes migrates in response to CXCL12 and traffics to the lungs in a murine model of bleomycin-induced pulmonary fibrosis. Next, we demonstrated that murine CD45+Col I+CXCR4+ fibrocytes also traffic to the lungs in response to a bleomycin challenge. Maximal intrapulmonary recruitment of CD45+Col I+CXCR4+ fibrocytes directly correlated with increased collagen deposition in the lungs. Treatment of bleomycin-exposed animals with specific neutralizing anti-CXCL12 Ab’s inhibited intrapulmonary recruitment of CD45+Col I+CXCR4+ circulating fibrocytes and attenuated lung fibrosis. Thus, our results demonstrate, we believe for the first time, that circulating fibrocytes contribute to the pathogenesis of pulmonary fibrosis.
Authors
Roderick J. Phillips, Marie D. Burdick, Kurt Hong, Marin A. Lutz, Lynne A. Murray, Ying Ying Xue, John A. Belperio, Michael P. Keane, Robert M. Strieter
Total citations by year
Citation information
Citations to this article (506)
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N Kuroda, M Masuya, I Tawara, J Tsuboi, M Yoneda, K Nishikawa, Y Kageyama, K Hachiya, K Ohishi, H Miwa, R Yamada, Y Hamada, K Tanaka, T Kato, Y Takei, N Katayama |
Scientific Reports | 2019 |
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Effects of high glucose on proliferation and function of circulating fibrocytes: Involvement of CXCR4/SDF‑1 axis
Y Weng, J Lou, X Liu, S Lin, C Xu, C Du, L Tang |
International journal of molecular medicine | 2019 |
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Depletion of Bone Marrow-Derived Fibrocytes Attenuates TAA-Induced Liver Fibrosis in Mice
F Hempel, M Roderfeld, R Savai, A Sydykov, K Irungbam, R Schermuly, R Voswinckel, K Köhler, Y Churin, L Kiss, J Bier, J Pons-Kühnemann, E Roeb |
Cells | 2019 |
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Pirfenidone activates cannabinoid receptor 2 in a mouse model of bleomycin‑induced pulmonary fibrosis
J Liu, G Shi |
Experimental and therapeutic medicine | 2019 |
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Systemic Molecular Mediators of Inflammation Differentiate Between Crohn’s Disease and Ulcerative Colitis, Implicating Threshold Levels of IL-10 and Relative Ratios of Pro-inflammatory Cytokines in Therapy
MG Kiernan, JC Coffey, SM Sahebally, P Tibbitts, EM Lyons, E Oleary, F Owolabi, CP Dunne |
Journal of Crohn's & colitis | 2019 |
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Correlation between circulating fibrocytes and dermal thickness in limited cutaneous systemic sclerosis patients: a pilot study.
Ruaro B, Soldano S, Smith V, Paolino S, Contini P, Montagna P, Pizzorni C, Casabella A, Tardito S, Sulli A, Cutolo M |
Rheumatology International | 2019 |
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Mucosal Bromodomain-Containing Protein 4 (BRD4) Mediates Aeroallergen-induced Inflammation and Remodeling
B Tian, K Hosoki, Z Liu, J Yang, Y Zhao, H Sun, J Zhou, E Rytting, L Kaphalia, WJ Calhoun, S Sur, AR Brasier |
Journal of Allergy and Clinical Immunology | 2018 |
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Sca-1 + cardiac fibroblasts promote development of heart failure
G Chen, W Bracamonte-Baran, NL Diny, X Hou, MV Talor, K Fu, Y Liu, G Davogustto, H Vasquez, H Taegtmeyer, OH Frazier, A Waisman, SJ Conway, F Wan, D Čiháková |
European Journal of Immunology | 2018 |
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MEKK1, JNK, and SMAD3 mediate CXCL12-stimulated connective tissue growth factor expression in human lung fibroblasts
CH Lin, CH Shih, YC Lin, YL Yang, BC Chen |
Journal of Biomedical Science | 2018 |
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The Development of Serum Amyloid P as a Possible Therapeutic
D Pilling, RH Gomer |
Frontiers in immunology | 2018 |
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Elevated Circulating Fibrocytes Is a Marker of Left Atrial Fibrosis and Recurrence of Persistent Atrial Fibrillation
Y Liu, XH Niu, X Yin, YJ Liu, C Han, J Yang, X Huang, X Yu, L Gao, YZ Yang, YL Xia, HH Li |
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease | 2018 |
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NMDA receptor activation inhibits the anti-fibrotic effect of BM-MSCs on bleomycin-induced pulmonary fibrosis
XH Li, C Li, Y Tang, YH Huang, QM Cheng, XT Huang, F Zhao, CX Hao, DD Feng, JP Xu, J Han, S Tang, W Liu, S Yue, ZQ Luo |
American journal of physiology. Lung cellular and molecular physiology | 2018 |
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Fibroblast-to-myofibroblast transition in bronchial asthma
M Michalik, K Wójcik-Pszczoła, M Paw, D Wnuk, P Koczurkiewicz, M Sanak, E Pękala, Z Madeja |
Cellular and Molecular Life Sciences | 2018 |
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Fibroblasts in the Tumor Microenvironment: Shield or Spear?
T Alkasalias, L Moyano-Galceran, M Arsenian-Henriksson, K Lehti |
International journal of molecular sciences | 2018 |
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40 YEARS OF IGF1: IGF1 receptor and thyroid-associated ophthalmopathy
M Mohyi, TJ Smith |
Journal of Molecular Endocrinology | 2018 |
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Radiation-induced pulmonary gene expression changes are attenuated by the CTGF antibody Pamrevlumab
MD Sternlicht, U Wirkner, S Bickelhaupt, RL Perez, A Tietz, KE Lipson, TW Seeley, PE Huber |
Respiratory Research | 2018 |
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Anti-fibrotic Effects of CXCR4-Targeting i-body AD-114 in Preclinical Models of Pulmonary Fibrosis
K Griffiths, DM Habiel, J Jaffar, U Binder, WG Darby, CG Hosking, A Skerra, GP Westall, CM Hogaboam, M Foley |
Scientific Reports | 2018 |
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Transient Blockade of Endothelin-1 Mitigates Amiodarone-Induced Pulmonary Fibrosis
X Liu, N Khadtare, H Patel, R Stephani, Jerome |
Lung | 2018 |
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Effects of CTLA4-Ig treatment on circulating fibrocytes and skin fibroblasts from the same systemic sclerosis patients: an in vitro assay
M Cutolo, S Soldano, P Montagna, AC Trombetta, P Contini, B Ruaro, A Sulli, S Scabini, E Stratta, S Paolino, C Pizzorni, V Smith, R Brizzolara |
Arthritis Research & Therapy | 2018 |
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Fibrocytes are increased in lung and peripheral blood of patients with idiopathic pulmonary fibrosis
P Heukels, JA van Hulst, M van Nimwegen, CE Boorsma, BN Melgert, LM van den Toorn, KA Boomars, MS Wijsenbeek, H Hoogsteden, JH von der Thüsen, RW Hendriks, M Kool, B van den Blink |
Respiratory Research | 2018 |
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Therapeutic targets for inflammation-mediated airway remodeling in chronic lung disease
AR Brasier |
Expert Review of Respiratory Medicine | 2018 |
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Potential Roles of CD34+ Fibrocytes Masquerading as Orbital Fibroblasts in Thyroid-Associated Ophthalmopathy
TJ Smith |
The Journal of clinical endocrinology and metabolism | 2018 |
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The Role of Immunity and Inflammation in IPF Pathogenesis
Butler MW, Keane MP |
Idiopathic Pulmonary Fibrosis | 2018 |
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Hsp90 Regulation of Fibroblast Activation in Pulmonary Fibrosis
Vishwaraj Sontake, Yunguan Wang, Rajesh Kasam, Debora Sinner, G. Bhanuprakash Reddy, Anjaparavanda Naren, Francis McCormack, Eric S. White, Anil Jegga, Satish K Madala |
JCI Insight | 2017 |
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Loss of Twist1 in the Mesenchymal Compartment Promotes Increased Fibrosis in Experimental Lung Injury by Enhanced Expression of CXCL12
J Tan, JR Tedrow, M Nouraie, JA Dutta, DT Miller, X Li, S Yu, Y Chu, B Juan-Guardela, N Kaminski, K Ramani, PS Biswas, Y Zhang, DJ Kass |
Journal of immunology (Baltimore, Md. : 1950) | 2017 |
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Dietary NaCl affects bleomycin-induced lung fibrosis in mice
W Chen, D Pilling, RH Gomer |
Experimental Lung Research | 2017 |
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Circulating fibrocyte mobilization in negative pressure wound therapy
D Chen, Y Zhao, Z Li, K Shou, X Zheng, P Li, B Qi, A Yu |
Journal of Cellular and Molecular Medicine | 2017 |
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Spoiling for a Fight: B Lymphocytes As Initiator and Effector Populations within Tertiary Lymphoid Organs in Autoimmunity and Transplantation
J Alsughayyir, GJ Pettigrew, R Motallebzadeh |
Frontiers in immunology | 2017 |
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Hypoxia-Inducible Factor 1α Signaling Promotes Repair of the Alveolar Epithelium after Acute Lung Injury
J McClendon, NL Jansing, EF Redente, A Gandjeva, Y Ito, SP Colgan, A Ahmad, DW Riches, HA Chapman, RJ Mason, RM Tuder, RL Zemans |
The American Journal of Pathology | 2017 |
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Circulating fibrocytes as biomarkers of impaired lung function in adults with sickle cell disease
B Mehrad, MD Burdick, NJ Wandersee, KS Shahir, L Zhang, PM Simpson, RM Strieter, JJ Field |
Blood Advances | 2017 |
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Mesenchymal stem cells in idiopathic pulmonary fibrosis
X Li, S Yue, Z Luo |
Oncotarget | 2017 |
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Fibroblasts: Diverse Cells Critical to Biomaterials Integration
RT Hannan, SM Peirce, TH Barker |
ACS Biomaterials Science & Engineering | 2017 |
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Essential involvement of the CX3CL1-CX3CR1 axis in bleomycin-induced pulmonary fibrosis via regulation of fibrocyte and M2 macrophage migration
Y Ishida, A Kimura, M Nosaka, Y Kuninaka, H Hemmi, I Sasaki, T Kaisho, N Mukaida, T Kondo |
Scientific Reports | 2017 |
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Allogeneic Human Mesenchymal Stem Cells in Patients With Idiopathic Pulmonary Fibrosis via Intravenous Delivery (AETHER)
MK Glassberg, J Minkiewicz, RL Toonkel, ES Simonet, GA Rubio, D DiFede, S Shafazand, A Khan, MV Pujol, VF LaRussa, LH Lancaster, GD Rosen, J Fishman, YN Mageto, A Mendizabal, JM Hare |
Chest | 2017 |
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Heterogeneity of Fibroblasts and Myofibroblasts in Pulmonary Fibrosis
DM Habiel, CM Hogaboam |
Current Pathobiology Reports | 2017 |
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Anti-fibrotic efficacy of nintedanib in pulmonary fibrosis via the inhibition of fibrocyte activity
S Sato, S Shinohara, S Hayashi, S Morizumi, S Abe, H Okazaki, Y Chen, H Goto, Y Aono, H Ogawa, K Koyama, H Nishimura, H Kawano, Y Toyoda, H Uehara, Y Nishioka |
Respiratory Research | 2017 |
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R1R2 peptide ameliorates pulmonary fibrosis in mice through fibrocyte migration and differentiation
HY Chiang, PH Chu, TH Lee, B Ryffel |
PloS one | 2017 |
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The role of periostin in lung fibrosis and airway remodeling
DN ODwyer, BB Moore |
Cellular and Molecular Life Sciences | 2017 |
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Radiation induced pulmonary fibrosis as a model of progressive fibrosis: Contributions of DNA damage, inflammatory response and cellular senescence genes
TA Beach, CJ Johnston, AM Groves, JP Williams, JN Finkelstein |
Experimental Lung Research | 2017 |
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Two-Way Conversion between Lipogenic and Myogenic Fibroblastic Phenotypes Marks the Progression and Resolution of Lung Fibrosis
EE Agha, A Moiseenko, V Kheirollahi, SD Langhe, S Crnkovic, G Kwapiszewska, D Kosanovic, F Schwind, RT Schermuly, I Henneke, BA MacKenzie, J Quantius, S Herold, A Ntokou, K Ahlbrecht, RE Morty, A Günther, W Seeger, S Bellusci |
Cell Stem Cell | 2017 |
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Cigarette smoke challenges bone marrow mesenchymal stem cell capacities in guinea pig
O Tura-Ceide, B Lobo, T Paul, R Puig-Pey, N Coll-Bonfill, J García-Lucio, V Smolders, I Blanco, JA Barberà, VI Peinado |
Respiratory Research | 2017 |
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Blood Biomarkers in Idiopathic Pulmonary Fibrosis
J Guiot, C Moermans, M Henket, JL Corhay, R Louis |
Lung | 2017 |
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Circulating fibrocytes are involved in inflammation and leukocyte trafficking in neonates with necrotizing enterocolitis:
Y Liu, S Qingjuan, Z Gao, C Deng, Y Wang, C Guo |
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Fibrocyte measurement in peripheral blood correlates with number of cultured mature fibrocytes in vitro and is a potential biomarker for interstitial lung disease in Rheumatoid Arthritis
SA Just, H Lindegaard, EK Hejbøl, JR Davidsen, N Bjerring, SW Hansen, HD Schrøder, IM Hansen, T Barington, C Nielsen |
Respiratory Research | 2017 |
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Transglutaminase 2 in human diseases
Z Szondy, I Korponay-Szabó, R Király, Z Sarang, GJ Tsay |
BioMedicine | 2017 |
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MicroRNA-101 attenuates pulmonary fibrosis by inhibiting fibroblast proliferation and activation
C Huang, X Xiao, Y Yang, A Mishra, Y Liang, X Zeng, X Yang, D Xu, MR Blackburn, CA Henke, L Liu |
The Journal of biological chemistry | 2017 |
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Pathway-based detection of idiopathic pulmonary fibrosis at an early stage
G Zhou, F Zhang, Y Liu, B Sun |
Molecular medicine reports | 2017 |
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Pulmonary toxicity generated from radiotherapeutic treatment of thoracic malignancies (Review)
G Deng, N Liang, J Xie, H Luo, L Qiao, J Zhang, D Wang, J Zhang |
Oncology Letters | 2017 |
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Protective effect of human serum amyloid P on CCl4-induced acute liver injury in mice
M Cong, W Zhao, T Liu, P Wang, X Fan, Q Zhai, X Bao, D Zhang, H You, T Kisseleva, D Brenner, J Jia, H Zhuang |
International journal of molecular medicine | 2017 |
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Endothelial Microparticles are Associated to Pathogenesis of Idiopathic Pulmonary Fibrosis
NC Bacha, A Blandinieres, E Rossi, N Gendron, N Nevo, S Lecourt, CL Guerin, JM Renard, P Gaussem, E Angles-Cano, CM Boulanger, D Israel-Biet, DM Smadja |
Stem Cell Reviews and Reports | 2017 |
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Mesenchymal stem cells: A double-edged sword in radiation-induced lung injury: MSCs and radiation-induced lung injury
Y Yao, Z Zheng, Q Song |
Thoracic Cancer | 2017 |
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Mechanisms of carbon nanotube-induced pulmonary fibrosis: a physicochemical characteristic perspective
KS Duke, JC Bonner |
Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology | 2017 |
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Regulation of myofibroblast accumulation and lung fibrosis by Tbx4
ting xie, Jiurong Liang, Ningshan Liu, Caijuan Huan, yanli zhang, Weijia Liu, Maya Kumar, Rui Xiao, Jeanine M. D'Armiento, Daniel Metzger, Pierre Chambon, Virginia Papaioannou, Barry R. Stripp, Dianhua Jiang, Paul W. Noble |
Journal of Clinical Investigation | 2016 |
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Vaccinia vaccine-based immunotherapy arrests and reverses established pulmonary fibrosis
Samuel Collins, Yee Chan-Li, Min-Hee Oh, Christine Vigeland, Nathachit Limjunyawong, Wayne Mitzner, Jonathan Powell, Maureen Horton |
JCI Insight | 2016 |
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Cardiomyocyte-derived CXCL12 is not involved in cardiogenesis but plays a crucial role in myocardial infarction
S Mühlstedt, SK Ghadge, J Duchene, F Qadri, A Järve, L Vilianovich, E Popova, A Pohlmann, T Niendorf, P Boyé, C Özcelik, M Bader |
Journal of Molecular Medicine | 2016 |
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Establishment of a mouse model for pulmonary inflammation and fibrosis by intratracheal instillation of polyhexamethyleneguanidine phosphate
SJ Lee, JH Park, JY Lee, YJ Jeong, JA Song, K Lee, DJ Kim |
Journal of Toxicologic Pathology | 2016 |
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Identification and Function of Fibrocytes in Skeletal Muscle Injury Repair and Muscular Dystrophy
X Wang, W Zhao, RM Ransohoff, L Zhou |
Journal of immunology (Baltimore, Md. : 1950) | 2016 |
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Controversies over the Epithelial-to-Mesenchymal Transition in Liver Fibrosis
K Taura, K Iwaisako, E Hatano, S Uemoto |
Journal of Clinical Medicine | 2016 |
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Impact of a CXCL12/CXCR4 Antagonist in Bleomycin (BLM) Induced Pulmonary Fibrosis and Carbon Tetrachloride (CCl4) Induced Hepatic Fibrosis in Mice
LN Chow, P Schreiner, BY Ng, B Lo, MR Hughes, RW Scott, V Gusti, S Lecour, E Simonson, I Manisali, I Barta, KM McNagny, J Crawford, M Webb, TM Underhill, P Mukhopadhyay |
PloS one | 2016 |
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Lung Pericytes and Resident Fibroblasts
L Barron, SA Gharib, JS Duffield |
The American Journal of Pathology | 2016 |
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Loss of CCR2 signaling alters leukocyte recruitment and exacerbates γ-herpesvirus-induced pneumonitis and fibrosis following bone marrow transplantation
SJ Gurczynski, MC Procario, DN O'Dwyer, CA Wilke, BB Moore |
American journal of physiology. Lung cellular and molecular physiology | 2016 |
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Searching for a good model for systemic sclerosis: the molecular profile and vascular changes occurring in UCD-200 chickens strongly resemble the early phase of human systemic sclerosis
P Cipriani, PD Benedetto, H Dietrich, P Ruscitti, V Liakouli, F Carubbi, I Pantano, O Berardicurti, R Sgonc, R Giacomelli |
Archives of Medical Science : AMS | 2016 |
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MHC-compatible bone marrow stromal/stem cells trigger fibrosis by activating host T cells in a scleroderma mouse model: ( A , B ) Transplantation model with different combinations of syngeneic (white) and mismatched (black) HSCs and BMSCs co-transplanted into BALB/c mice. ( B , i–v) (i) Negative control, (ii) mismatched BMSC transplantation, (iii) syngeneic BMSC transplantation, (iv) positive control, and (v) mismatched MSC-depleted WBMT. Excessive fibrosis (deep blue, and ∗) in various organs was observed in mismatched BMSC transplanted mice after 3 weeks. Double arrows indicate epidermal and dermal thickness. The fibrotic areas were assessed as the ratio of the blue-stained area per field. D, duct. Minimal Mallory staining areas (▲) in (iii) and (v) are physiological changes and necessary to support the structure of ducts and intestinal walls. Scale bar, 100 μm (50 μm in liver). ( C ) HSP47 + fibroblasts in the lacrimal glands were significantly higher following mismatched BMSC transplantation (red) compared to syngeneic BMSC (blue), and BMSC-depleted WBM transplantation (green). The number of HSP47 + cells in negative control (i) (blue), and syngeneic MSC transplantation (iii) (blue), and mismatched MSC transplantation (ii) (red), and positive control (iv) (red), and mismatched MSC-depleted WBMT (green). Data are shown as mean ± SD, #pD) Tear volume in the same groups described in ( C ). Data are shown as mean ± SD, n = 2-5 per group, *pE, F) The degree of fibrosis (blue) in the lacrimal glands of mismatched BMSC recipients was dose dependent. Excessive fibrotic areas are shown in deep blue (∗). Data are shown as mean ± SD, n = 3. Scale bar, 100 μm. *p
Y Ogawa, S Morikawa, H Okano, Y Mabuchi, S Suzuki, T Yaguchi, Y Sato, S Mukai, S Yaguchi, T Inaba, S Okamoto, Y Kawakami, K Tsubota, Y Matsuzaki, S Shimmura |
eLife | 2016 |
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Tumor-associated fibroblasts predominantly come from local and not circulating precursors
A Arina, C Idel, EM Hyjek, ML Alegre, Y Wang, VP Bindokas, RR Weichselbaum, H Schreiber |
Proceedings of the National Academy of Sciences | 2016 |
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From Here to There, Progenitor Cells and Stem Cells Are Everywhere in Lung Vascular Remodeling
RL Heise, PA Link, L Farkas |
Frontiers in Pediatrics | 2016 |
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Periostin regulates fibrocyte function to promote myofibroblast differentiation and lung fibrosis
SL Ashley, CA Wilke, KK Kim, BB Moore |
Mucosal Immunology | 2016 |
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Human Very Small Embryonic-Like Stem Cells Are Present in Normal Peripheral Blood of Young, Middle-Aged, and Aged Subjects
H Sovalat, M Scrofani, A Eidenschenk, P Hénon |
Stem Cells International | 2016 |
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Therapeutic potential of adipose stem cell-derived conditioned medium against pulmonary hypertension and lung fibrosis: Adipose stem cells attenuate pulmonary hypertension/fibrosis
A Rathinasabapathy, E Bruce, A Espejo, A Horowitz, DR Sudhan, A Nair, D Guzzo, J Francis, MK Raizada, V Shenoy, MJ Katovich |
British Journal of Pharmacology | 2016 |
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Organizing pneumonia in mice and men
N Izykowski, M Kuehnel, K Hussein, K Mitschke, M Gunn, S Janciauskiene, A Haverich, G Warnecke, F Laenger, U Maus, D Jonigk |
Journal of Translational Medicine | 2016 |
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Circulating fibrocytes as predictors of adverse events in unstable angina
EC Keeley, RC Schutt, MA Marinescu, MD Burdick, RM Strieter, B Mehrad |
Translational Research | 2016 |
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Fibroblasts, an inconspicuous but essential player in colon cancer development and progression
N Mukaida, S Sasaki |
World journal of gastroenterology : WJG | 2016 |
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i-bodies, Human Single Domain Antibodies That Antagonize Chemokine Receptor CXCR4
K Griffiths, O Dolezal, B Cao, SK Nilsson, HB See, KD Pfleger, M Roche, PR Gorry, A Pow, K Viduka, K Lim, BG Lu, DH Chang, T Murray-Rust, M Kvansakul, MA Perugini, C Dogovski, M Doerflinger, Y Zhang, K Parisi, JL Casey, SD Nuttall, M Foley |
The Journal of biological chemistry | 2016 |
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Immunohistochemical detection of intrathrombotic fibrocytes and its application to thrombus age estimation in murine deep vein thrombosis model
M Nosaka, Y Ishida, A Kimura, T Kawaguchi, H Yamamoto, Y Kuninaka, T Kondo |
International Journal of Legal Medicine | 2016 |
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Blocking the 4-1BB Pathway Ameliorates Crystalline Silica-induced Lung Inflammation and Fibrosis in Mice
C Li, S Du, Y Lu, X Lu, F Liu, Y Chen, D Weng, J Chen |
Theranostics | 2016 |
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Intersection of Chemokine and TSH Receptor Pathways in Human Fibrocytes: Emergence of CXCL-12/CXCR4 Cross Talk Potentially Relevant to Thyroid-Associated Ophthalmopathy
R Fernando, SJ Atkins, TJ Smith |
Endocrinology | 2016 |
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Fibrocytes Regulate Wilms Tumor 1-Positive Cell Accumulation in Severe Fibrotic Lung Disease
V Sontake, SK Shanmukhappa, BA DiPasquale, GB Reddy, M Medvedovic, WD Hardie, ES White, SK Madala |
Journal of immunology (Baltimore, Md. : 1950) | 2015 |
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Macrophages During the Fibrotic Process: M2 as Friend and Foe
TT Braga, JS Agudelo, NO Camara |
Frontiers in immunology | 2015 |
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Regulation of myofibroblast differentiation by miR-424 during epithelial-to-mesenchymal transition
X Xiao, C Huang, C Zhao, X Gou, LK Senavirathna, M Hinsdale, P Lloyd, L Liu |
Archives of Biochemistry and Biophysics | 2015 |
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Fibrocyte-like cells mediate acquired resistance to anti-angiogenic therapy with bevacizumab
A Mitsuhashi, H Goto, A Saijo, VT Trung, Y Aono, H Ogino, T Kuramoto, S Tabata, H Uehara, K Izumi, M Yoshida, H Kobayashi, H Takahashi, M Gotoh, S Kakiuchi, M Hanibuchi, S Yano, H Yokomise, S Sakiyama, Y Nishioka |
Nature Communications | 2015 |
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Bone marrow-derived fibrocytes contribute to liver fibrosis
J Xu, T Kisseleva |
Experimental biology and medicine (Maywood, N.J.) | 2015 |
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Bone marrow-derived fibrocytes contribute to liver fibrosis
J Xu, T Kisseleva |
Experimental biology and medicine (Maywood, N.J.) | 2015 |
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The Long Pentraxin PTX3 Promotes Fibrocyte Differentiation
D Pilling, N Cox, V Vakil, JS Verbeek, RH Gomer, G Zissel |
PloS one | 2015 |
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Rapid detection of circulating fibrocytes by flowcytometry in idiopathic pulmonary fibrosis
EH Alhamad, FA Al-Kassimi, A Almogren, MO ElRab, M Kolb, Z Shakoor, S Maharaj |
Annals of thoracic medicine | 2015 |
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T Helper 2 Cytokine Signaling in Bone Marrow-Derived Fibroblasts: A Target for Renal Fibrosis
N Sakai, T Wada |
Journal of the American Society of Nephrology : JASN | 2015 |
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The Origin of Matrix-Producing Cells that Contribute to Aortic Fibrosis in Hypertension
J Wu, KR Montaniel, MA Saleh, L Xiao, W Chen, GK Owens, JD Humphrey, MW Majesky, DT Paik, AK Hatzopoulos, MS Madhur, DG Harrison |
Hypertension | 2015 |
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TSH-receptor-expressing fibrocytes and thyroid-associated ophthalmopathy
TJ Smith |
Nature Reviews Endocrinology | 2015 |
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An Experimental Model-Based Exploration of Cytokines in Ablative Radiation-Induced Lung Injury In Vivo and In Vitro
ZY Hong, KH Song, JH Yoon, J Cho, MD Story |
Pneumologie - Pneumology | 2015 |
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Increased circulating fibrocytes are associated with higher reticulocyte percent in children with sickle cell anemia: Fibrocytes in Sickle Cell Anemia
MS Karafin, S Dogra, M Rodeghier, M Burdick, B Mehrad, CE Rose, RM Strieter, MR DeBaun, RC Strunk, JJ Field |
Pediatric Pulmonology | 2015 |
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Immunohistochemical Expression of CXCR4 on Breast Cancer and Its Clinical Significance
MO Kishima, CE de Oliveira, BK Banin-Hirata, R Losi-Guembarovski, KB de Oliveira, MK Amarante, MA Watanabe |
Analytical cellular pathology (Amsterdam) | 2015 |
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TSH-Mediated TNFα Production in Human Fibrocytes Is Inhibited by Teprotumumab, an IGF-1R Antagonist
H Chen, SJ Shan, T Mester, YH Wei, RS Douglas, N Vij |
PloS one | 2015 |
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TNF-α–stimulated fibroblasts secrete lumican to promote fibrocyte differentiation
D Pilling, V Vakil, N Cox, RH Gomer |
Proceedings of the National Academy of Sciences | 2015 |
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Number, activation, and differentiation of circulating fibrocytes correlate with asthma severity
R Shipe, MD Burdick, BA Strieter, L Liu, YM Shim, S Sung, WG Teague, B Mehrad, RM Strieter, CE Rose |
Journal of Allergy and Clinical Immunology | 2015 |
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Radiation‑induced pulmonary injury accelerated pulmonary metastasis in a mouse model of breast cancer
HY Gong, WG Hu, QY Hu, XP Li, QB Song |
Oncology Letters | 2015 |
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Silica promotes the transdifferentiation of rat circulating fibrocytes in�vitro
W Yao, S Liu, J Li, C Hao |
Molecular medicine reports | 2015 |
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Levels of circulating endothelial cells are low in idiopathic pulmonary fibrosis and are further reduced by anti-fibrotic treatments
SD Biasi, S Cerri, E Bianchini, L Gibellini, E Persiani, G Montanari, F Luppi, CM Carbonelli, L Zucchi, M Bocchino, AS Zamparelli, C Vancheri, G Sgalla, L Richeldi, A Cossarizza |
BMC Medicine | 2015 |
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Histochemical Detection of Collagen Fibers by Sirius Red/Fast Green Is More Sensitive than van Gieson or Sirius Red Alone in Normal and Inflamed Rat Colon
C Segnani, C Ippolito, L Antonioli, C Pellegrini, C Blandizzi, A Dolfi, N Bernardini, V Lionetti |
PloS one | 2015 |
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ING5 inhibits cancer aggressiveness via preventing EMT and is a potential prognostic biomarker for lung cancer
F Zhang, X Zhang, J Meng, Y Zhao, X Liu, Y Liu, Y Wang, Y Li, Y Sun, Z Wang, Q Mei, T Zhang |
Oncotarget | 2015 |
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Fibrocytes at 20 Years.
Bucala R |
Molecular Medicine | 2015 |
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Tracking the elusive fibrocyte: Identification and characterization of collagen producing hematopoietic lineage cells during murine wound healing
H Suga, RC Rennert, M Rodrigues, M Sorkin, JP Glotzbach, M Januszyk, T Fujiwara, MT Longaker, GC Gurtner |
Stem Cells | 2014 |
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Prostatic Inflammation Induces Fibrosis in a Mouse Model of Chronic Bacterial Infection
L Wong, PR Hutson, W Bushman, P Thumbikat |
PloS one | 2014 |
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Mechanical Ventilation–associated Lung Fibrosis in Acute Respiratory Distress Syndrome: A Significant Contributor to Poor Outcome
NE Cabrera-Benitez, JG Laffey, M Parotto, PM Spieth, J Villar, H Zhang, AS Slutsky |
Anesthesiology | 2014 |
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Fibrocytes Are Not an Essential Source of Type I Collagen during Lung Fibrosis
KR Kleaveland, M Velikoff, J Yang, M Agarwal, RA Rippe, BB Moore, KK Kim |
Journal of immunology (Baltimore, Md. : 1950) | 2014 |
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Activated alveolar epithelial cells initiate fibrosis through autocrine and paracrine secretion of connective tissue growth factor
J Yang, M Velikoff, E Canalis, JC Horowitz, KK Kim |
American journal of physiology. Lung cellular and molecular physiology | 2014 |
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CXCR4 Inhibition Ameliorates Severe Obliterative Pulmonary Hypertension and Accumulation of C-Kit+ Cells in Rats
D Farkas, D Kraskauskas, JI Drake, AA Alhussaini, V Kraskauskiene, HJ Bogaard, CD Cool, NF Voelkel, L Farkas, W Shi |
PloS one | 2014 |
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The wound healing, chronic fibrosis, and cancer progression triad
B Rybinski, J Franco-Barraza, E Cukierman |
Physiological genomics | 2014 |
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Activated Wnt signaling induces myofibroblast differentiation of mesenchymal stem cells, contributing to pulmonary fibrosis
Z Sun, C Wang, C Shi, F Sun, X Xu, W Qian, S Nie, X Han |
International journal of molecular medicine | 2014 |
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The types of hepatic myofibroblasts contributing to liver fibrosis of different etiologies
J Xu, X Liu, Y Koyama, P Wang, T Lan, IG Kim, IH Kim, HY Ma, T Kisseleva |
Frontiers in pharmacology | 2014 |
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Pirfenidone inhibits fibrocyte accumulation in the lungs in bleomycin-induced murine pulmonary fibrosis
M Inomata, K Kamio, A Azuma, K Matsuda, N Kokuho, Y Miura, H Hayashi, T Nei, K Fujita, Y Saito, A Gemma |
Respiratory Research | 2014 |
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Hematopoietic and Mesenchymal Stem Cells for the Treatment of Chronic Respiratory Diseases: Role of Plasticity and Heterogeneity
M Conese, D Piro, A Carbone, S Castellani, SD Gioia |
The Scientific World JOURNAL | 2014 |
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CXCL12 Induces Connective Tissue Growth Factor Expression in Human Lung Fibroblasts through the Rac1/ERK, JNK, and AP-1 Pathways
CH Lin, CH Shih, CC Tseng, CC Yu, YJ Tsai, MY Bien, BC Chen, TS Acott |
PloS one | 2014 |
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Persistent Lung Inflammation and Fibrosis in Serum Amyloid P Component (Apcs-/-) Knockout Mice
D Pilling, RH Gomer, G Zissel |
PloS one | 2014 |
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Inhibition of Angiogenesis, Fibrosis and Thrombosis by Tetramethylpyrazine: Mechanisms Contributing to the SDF-1/CXCR4 Axis
X Cai, Z Chen, X Pan, L Xia, P Chen, Y Yang, H Hu, J Zhang, K Li, J Ge, K Yu, J Zhuang, M Bader |
PloS one | 2014 |
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Cellular Mechanisms of Tissue Fibrosis. 7. New insights into the cellular mechanisms of pulmonary fibrosis
CE Barkauskas, PW Noble |
American journal of physiology. Cell physiology | 2014 |
|
Future Directions in Idiopathic Pulmonary Fibrosis Research. An NHLBI Workshop Report
TS Blackwell, AM Tager, Z Borok, BB Moore, DA Schwartz, KJ Anstrom, Z Bar-Joseph, P Bitterman, MR Blackburn, W Bradford, KK Brown, HA Chapman, HR Collard, GP Cosgrove, R Deterding, R Doyle, KR Flaherty, CK Garcia, JS Hagood, CA Henke, E Herzog, CM Hogaboam, JC Horowitz, TE King, JE Loyd, WE Lawson, CB Marsh, PW Noble, I Noth, D Sheppard, J Olsson, LA Ortiz, TG O’Riordan, TD Oury, G Raghu, J Roman, PJ Sime, TH Sisson, D Tschumperlin, SM Violette, TE Weaver, RG Wells, ES White, N Kaminski, FJ Martinez, TA Wynn, VJ Thannickal, JP Eu |
American journal of respiratory and critical care medicine | 2014 |
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Protein Tyrosine Phosphatase α Mediates Profibrotic Signaling in Lung Fibroblasts through TGF-β Responsiveness
Y Aschner, AP Khalifah, N Briones, C Yamashita, L Dolgonos, SK Young, MN Campbell, DW Riches, EF Redente, WJ Janssen, PM Henson, J Sap, N Vacaresse, A Kapus, CA McCulloch, RL Zemans, GP Downey |
The American Journal of Pathology | 2014 |
|
Hypoxia and the extracellular matrix: drivers of tumour metastasis
DM Gilkes, GL Semenza, D Wirtz |
Nature Reviews Cancer | 2014 |
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Paracrine functions of fibrocytes to promote lung fibrosis
KR Kleaveland, BB Moore, KK Kim |
Expert Review of Respiratory Medicine | 2014 |
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Following the Path of CCL2 from Prostaglandins to Periostin in Lung Fibrosis
BB Moore |
American journal of respiratory cell and molecular biology | 2014 |
|
Microfluidic source-sink model reveals effects of biophysically distinct CXCL12 isoforms in breast cancer chemotaxis
SP Cavnar, P Ray, P Moudgil, SL Chang, KE Luker, JJ Linderman, S Takayama, GD Luker |
Integrative Biology | 2014 |
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Alternative strategies to manipulate fibrocyte involvement in the fibrotic tissue response: Pharmacokinetic inhibition and the feasibility of directed-adipogenic differentiation
DW Baker, YT Tsai, H Weng, L Tang |
Acta Biomaterialia | 2014 |
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Bone marrow derived “fibrocytes” contribute to tumor proliferation and fibrosis in gastric cancer
S Terai, S Fushida, T Tsukada, J Kinoshita, K Oyama, K Okamoto, I Makino, H Tajima, I Ninomiya, T Fujimura, S Harada, T Ohta |
Gastric Cancer | 2014 |
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IL-33 Enhanced the Proliferation and Constitutive Production of IL-13 and IL-5 by Fibrocytes
H Hayashi, A Kawakita, S Okazaki, H Murai, M Yasutomi, Y Ohshima |
BioMed Research International | 2014 |
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Heterogeneity in fibroblast proliferation and survival in idiopathic pulmonary fibrosis
DM Habiel, C Hogaboam |
Frontiers in pharmacology | 2014 |
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Fibrocytes in the fibrotic lung: altered phenotype detected by flow cytometry
C Reese, R Lee, M Bonner, B Perry, J Heywood, RM Silver, E Tourkina, RP Visconti, S Hoffman |
Frontiers in pharmacology | 2014 |
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CCL2 release by airway smooth muscle is increased in asthma and promotes fibrocyte migration
SR Singh, A Sutcliffe, D Kaur, S Gupta, D Desai, R Saunders, CE Brightling |
Allergy | 2014 |
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Class I HDACs regulate angiotensin II-dependent cardiac fibrosis via fibroblasts and circulating fibrocytes
SM Williams, L Golden-Mason, BS Ferguson, KB Schuetze, MA Cavasin, K Demos-Davies, ME Yeager, KR Stenmark, TA McKinsey |
Journal of Molecular and Cellular Cardiology | 2014 |
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First Identification of Resident and Circulating Fibrocytes in Dupuytren's Disease Shown to Be Inhibited by Serum Amyloid P and Xiapex
SA Iqbal, MJ Hayton, JS Watson, P Szczypa, A Bayat |
PloS one | 2014 |
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Brazilian green propolis modulates inflammation, angiogenesis and fibrogenesis in intraperitoneal implant in mice
LD Lima, SP Andrade, PP Campos, LS Barcelos, FM Soriani, SA Moura, MA Ferreira |
BMC complementary and alternative medicine | 2014 |
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Stromal reengineering to treat pancreas cancer
IM Stromnes, KE DelGiorno, PD Greenberg, SR Hingorani |
Carcinogenesis | 2014 |
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Cooperation between human fibrocytes and endothelial colony-forming cells increases angiogenesis via the CXCR4 pathway:
DM Smadja, P Dorfmüller, C Guerin, I Bieche, C Badoual, E Boscolo, M Kambouchner, A Cazes, O Mercier, M Humbert, P Gaussem, J Bischoff, D Israël-Biet |
Thrombosis and Haemostasis | 2014 |
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Walking along the Fibroblast Growth Factor 10 Route: A Key Pathway to Understand the Control and Regulation of Epithelial and Mesenchymal Cell-Lineage Formation during Lung Development and Repair after Injury
EE Agha, S Bellusci |
Scientifica | 2014 |
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A translational preclinical model of interstitial pulmonary fibrosis and pulmonary hypertension: mechanistic pathways driving disease pathophysiology
ER Jarman, VS Khambata, LY Ye, K Cheung, M Thomas, N Duggan, G Jarai |
Physiological Reports | 2014 |
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Circulating Fibrocytes as Biomarker of Prognosis in Hermansky-Pudlak Syndrome
A Trimble, BR Gochuico, TC Markello, R Fischer, WA Gahl, JK Lee, Y Kim, MD Burdick, RM Strieter, B Mehrad |
American journal of respiratory and critical care medicine | 2014 |
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Relationship of DNA Methylation and Gene Expression in Idiopathic Pulmonary Fibrosis
IV Yang, BS Pedersen, E Rabinovich, CE Hennessy, EJ Davidson, E Murphy, BJ Guardela, JR Tedrow, Y Zhang, MK Singh, M Correll, MI Schwarz, M Geraci, FC Sciurba, J Quackenbush, A Spira, N Kaminski, DA Schwartz |
American journal of respiratory and critical care medicine | 2014 |
|
Fibroblasts secrete Slit2 to inhibit fibrocyte differentiation and fibrosis
D Pilling, Z Zheng, V Vakil, RH Gomer |
Proceedings of the National Academy of Sciences | 2014 |
|
Deficiency of Kruppel-like factor KLF4 in myeloid-derived suppressor cells inhibits tumor pulmonary metastasis in mice accompanied by decreased fibrocytes
Y Shi, L Ou, S Han, M Li, MM Pena, EA Pena, C Liu, M Nagarkatti, D Fan, W Ai |
Oncogenesis | 2014 |
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Expression of Thyrotropin Receptor, Thyroglobulin, Sodium-Iodide Symporter, and Thyroperoxidase by Fibrocytes Depends on AIRE
R Fernando, Y Lu, SJ Atkins, T Mester, K Branham, TJ Smith |
The Journal of clinical endocrinology and metabolism | 2014 |
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Human Fibrocytes Express Multiple Antigens Associated With Autoimmune Endocrine Diseases
R Fernando, A Vonberg, SJ Atkins, S Pietropaolo, M Pietropaolo, TJ Smith |
The Journal of clinical endocrinology and metabolism | 2014 |
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CXCR4 Receptor Overexpression in Mesenchymal Stem Cells Facilitates Treatment of Acute Lung Injury in Rats
JX Yang, N Zhang, HW Wang, P Gao, QP Yang, QP Wen |
The Journal of biological chemistry | 2014 |
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Increased CD40+ Fibrocytes in Patients With Idiopathic Orbital Inflammation:
BJ Lee, S Atkins, A Ginter, VM Elner, CC Nelson, RS Douglas |
Ophthalmic Plastic & Reconstructive Surgery | 2014 |
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PI3K/AKT Pathway Mediates Induction of IL-1RA by TSH in Fibrocytes: Modulation by PTEN
B Li, TJ Smith |
The Journal of clinical endocrinology and metabolism | 2014 |
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Inhibition of murine fibrocyte differentiation by cross-linked IgG is dependent on Fc RI
D Pilling, JR Crawford, JS Verbeek, RH Gomer |
Journal of leukocyte biology | 2014 |
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Biphasic Presence of Fibrocytes in a Porcine Hypertrophic Scar Model:
TE Travis, MJ Mino, LT Moffatt, NA Mauskar, NJ Prindeze, P Ghassemi, JC Ramella-Roman, MH Jordan, JW Shupp |
Journal of Burn Care & Research | 2014 |
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Essential role of stem cell factor-c-Kit signalling pathway in bleomycin-induced pulmonary fibrosis
L Ding, V Dolgachev, Z Wu, T Liu, T Nakashima, Z Wu, M Ullenbruch, NW Lukacs, Z Chen, SH Phan |
The Journal of Pathology | 2013 |
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Vascular repair and regeneration as a therapeutic target for pulmonary arterial hypertension
L Farkas, M Kolb |
Respiration | 2013 |
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Implicating Exudate Macrophages and Ly-6C high Monocytes in CCR2-Dependent Lung Fibrosis following Gene-Targeted Alveolar Injury
JJ Osterholzer, MA Olszewski, BJ Murdock, GH Chen, JR Erb-Downward, N Subbotina, K Browning, Y Lin, RE Morey, JK Dayrit, JC Horowitz, RH Simon, TH Sisson |
Journal of immunology (Baltimore, Md. : 1950) | 2013 |
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Rapamycin Blocks Fibrocyte Migration and Attenuates Bronchiolitis Obliterans in a Murine Model
JR Gillen, Y Zhao, DA Harris, DJ LaPar, ML Stone, LG Fernandez, IL Kron, CL Lau |
The Annals of Thoracic Surgery | 2013 |
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Short-Course Rapamycin Treatment Preserves Airway Epithelium and Protects Against Bronchiolitis Obliterans
JR Gillen, Y Zhao, DA Harris, DJ LaPar, IL Kron, CL Lau |
The Annals of Thoracic Surgery | 2013 |
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Scleroderma pathogenesis: a pivotal role for fibroblasts as effector cells
AJ Gilbane, CP Denton, AM Holmes |
Arthritis Research & Therapy | 2013 |
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CCR2 regulates the uptake of bone marrow-derived fibroblasts in renal fibrosis
Y Xia, ML Entman, Y Wang |
PloS one | 2013 |
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Cytokines in chronic respiratory diseases
SP Atamas, SP Chapoval, AD Keegan |
F1000 biology reports | 2013 |
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New Light Is Shed on the Enigmatic Origin of the Lung Myofibroblast
IO Rosas, RM Kottman, PJ Sime |
American journal of respiratory and critical care medicine | 2013 |
|
Inhibition of the CXCL12/CXCR4-Axis as Preventive Therapy for Radiation-Induced Pulmonary Fibrosis
HK Shu, Y Yoon, S Hong, K Xu, H Gao, C Hao, E Torres-Gonzalez, C Nayra, M Rojas, H Shim, W Shi |
PloS one | 2013 |
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Lysophosphatidic acid accelerates lung fibrosis by inducing differentiation of mesenchymal stem cells into myofibroblasts
N Tang, Y Zhao, R Feng, Y Liu, S Wang, W Wei, Q Ding, MS An, J Wen, L Li |
Journal of Cellular and Molecular Medicine | 2013 |
|
Rapamycin Inhibits Transforming Growth Factor β1-Induced Fibrogenesis in Primary Human Lung Fibroblasts
Y Gao, X Xu, K Ding, Y Liang, D Jiang, H Dai |
Yonsei Medical Journal | 2013 |
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Gallic Acid Induces a Reactive Oxygen Species-Provoked c-Jun NH2-Terminal Kinase-Dependent Apoptosis in Lung Fibroblasts
CY Chen, KC Chen, TY Yang, HC Liu, SL Hsu |
Evidence-Based Complementary and Alternative Medicine | 2013 |
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Stromal cell regulation of homeostatic and inflammatory lymphoid organogenesis
MJ Kain, BM Owens |
Immunology | 2013 |
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Fibrocytes represent a novel MDSC subset circulating in patients with metastatic cancer
H Zhang, I Maric, MJ DiPrima, J Khan, RJ Orentas, RN Kaplan, CL Mackall |
Blood | 2013 |
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Thyrotropin regulates IL-6 expression in CD34+ fibrocytes: clear delineation of its cAMP-independent actions
N Raychaudhuri, R Fernando, TJ Smith |
PloS one | 2013 |
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The fibroproliferative response in acute respiratory distress syndrome: mechanisms and clinical significance
EL Burnham, WJ Janssen, DW Riches, M Moss, GP Downey |
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology | 2013 |
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Fibrocytes Are Involved in Inflammation as well as Fibrosis in the Pathogenesis of Crohn’s Disease
S Sazuka, T Katsuno, T Nakagawa, M Saito, K Saito, D Maruoka, T Matsumura, M Arai, H Miyauchi, H Matsubara, O Yokosuka |
Digestive Diseases and Sciences | 2013 |
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Nonmicrobial-mediated inflammatory airway diseases—an update
PB Babu, P Krishnamoorthy |
Journal of Physiology and Biochemistry | 2013 |
|
FELD better not thinking of metastases only when liver lesions appear after bleomycin-based treatment for non-seminoma testis from metastases
FY de Vos, SF Mulder, JP Drenth, ID Nagtegaal, JJ Fütterer, WT van der Graaf |
BMC Cancer | 2013 |
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Differential regulation of cell functions by CSD peptide subdomains
C Reese, S Dyer, B Perry, M Bonner, J Oates, A Hofbauer, W Sessa, P Bernatchez, RP Visconti, J Zhang, CM Hatfield, RM Silver, S Hoffman, E Tourkina |
Respiratory Research | 2013 |
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Bone marrow-derived progenitor cells in end-stage lung disease patients
SE Gilpin, K Lung, GT de Couto, M Cypel, M Sato, LG Singer, S Keshavjee, TK Waddell |
BMC Pulmonary Medicine | 2013 |
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Origins of increased airway smooth muscle mass in asthma
R Berair, R Saunders, CE Brightling |
BMC Medicine | 2013 |
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Functional interaction of cockroach allergens and mannose receptor (CD206) in human circulating fibrocytes
YM Tsai, SC Hsu, J Zhang, YF Zhou, B Plunkett, SK Huang, PS Gao |
PloS one | 2013 |
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Distant mesenchymal progenitors contribute to skin wound healing and produce collagen: evidence from a murine fetal microchimerism model
E Seppanen, E Roy, R Ellis, G Bou-Gharios, NM Fisk, K Khosrotehrani |
PloS one | 2013 |
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Involvement of CXCR4/CXCR7/CXCL12 Interactions in Inflammatory bowel disease
L Werner, H Guzner-Gur, I Dotan |
Theranostics | 2013 |
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Pericyte progenitors at the crossroads between fibrosis and regeneration
ML Steinhauser, RT Lee |
Circulation research | 2013 |
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Always cleave up your mess: targeting collagen degradation to treat tissue fibrosis
W McKleroy, TH Lee, K Atabai |
American journal of physiology. Lung cellular and molecular physiology | 2013 |
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CCL2/CCR2 augments the production of transforming growth factor-beta1, type 1 collagen and CCL2 by human CD45-/collagen 1-positive cells under high glucose concentrations
A Hara, N Sakai, K Furuichi, Y Sakai, M Takeya, R Bucala, N Mukaida, Y Takuwa, K Matsushima, S Kaneko, T Wada |
Clinical and Experimental Nephrology | 2013 |
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Promising Molecular Targets and Biomarkers for Male BPH and LUTS
M Gharaee-Kermani, JA Macoska |
Current Urology Reports | 2013 |
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IL-17A/F Modulates Fibrocyte Functions in Cooperation with CD40-Mediated Signaling
H Hayashi, A Kawakita, S Okazaki, M Yasutomi, H Murai, Y Ohshima |
Inflammation | 2013 |
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Mesenchymal Stem Cells as Vectors for Lung Cancer Therapy
KK Kolluri, GJ Laurent, SM Janes |
Respiration | 2013 |
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Associations Between Fibrocytes and Postcontrast Myocardial T 1 Times in Hypertrophic Cardiomyopathy
L Fang, A Beale, AH Ellims, X Moore, L Ling, AJ Taylor, J ChinDusting, AM Dart |
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease | 2013 |
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Fibrocytes in the Pathogenesis of Chronic Fibrotic Lung Disease
Loomis-King H, Moore BB |
Current respiratory medicine reviews | 2013 |
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Fibrocytes in pulmonary fibrosis: a brief synopsis
Maharaj S, Shimbori C, Kolb M |
European Respiratory Review | 2013 |
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Pulmonary Fibrosis: Patterns and Perpetrators
Paul W. Noble, Christina Barkauskas, Dianhua Jiang |
Journal of Clinical Investigation | 2012 |
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Pulmonary Vaccination as a Novel Treatment for Lung Fibrosis
SL Collins, Y Chan-Li, RW Hallowell, JD Powell, MR Horton |
PloS one | 2012 |
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Stem Cell Mobilization
MG Kolonin, PJ Simmons |
2012 | |
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Role of the Lysophospholipid Mediators Lysophosphatidic Acid and Sphingosine 1-Phosphate in Lung Fibrosis
BS Shea, AM Tager |
Proceedings of the American Thoracic Society | 2012 |
|
Molecular and cellular mechanisms of pulmonary fibrosis
NW Todd, IG Luzina, SP Atamas |
Fibrogenesis & Tissue Repair | 2012 |
|
Cytokine mediated tissue fibrosis
LA Borthwick, TA Wynn, AJ Fisher |
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease | 2012 |
|
Cellular and Molecular Mechanisms of Chronic Inflammation-Associated Organ Fibrosis
S Ueha, FH Shand, K Matsushima |
Frontiers in immunology | 2012 |
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Surfactant Protein-D Regulates Effector Cell Function and Fibrotic Lung Remodeling in Response to Bleomycin Injury
Y Aono, JG Ledford, S Mukherjee, H Ogawa, Y Nishioka, S Sone, MF Beers, PW Noble, JR Wright |
American journal of respiratory and critical care medicine | 2012 |
|
Smoking and Idiopathic Pulmonary Fibrosis
CK Oh, LA Murray, NA Molfino |
Pulmonary Medicine | 2012 |
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Genesis of the Myofibroblast in Lung Injury and Fibrosis
SH Phan |
Proceedings of the American Thoracic Society | 2012 |
|
The role of the myofibroblast in tumor stroma remodeling
M Otranto, V Sarrazy, F Bonté, B Hinz, G Gabbiani, A Desmouliere |
Cell adhesion & migration | 2012 |
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Caveolin-1 Signaling in Lung Fibrosis
E Tourkina, S Hoffman |
The open rheumatology journal | 2012 |
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Investigation of Telomerase/Telomeres system in Bone Marrow Mesenchymal Stem Cells derived from IPF and RA-UIP
KM Antoniou, GA Margaritopoulos, A Proklou, K Karagiannis, I Lasithiotaki, G Soufla, MC Kastrinaki, DA Spandidos, HA Papadaki, NM Siafakas |
Journal of inflammation (London, England) | 2012 |
|
Origin of Developmental Precursors Dictates the Pathophysiologic Role of Cardiac Fibroblasts
JR Crawford, SB Haudek, KA Cieslik, JA Trial, ML Entman |
Journal of Cardiovascular Translational Research | 2012 |
|
Fibrocytes and the pathogenesis of diffuse parenchymal lung disease
B Mehrad, RM Strieter |
Fibrogenesis & Tissue Repair | 2012 |
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Regulatory T cells reduce acute lung injury fibroproliferation by decreasing fibrocyte recruitment
BT Garibaldi, FR D'Alessio, JR Mock, DC Files, E Chau, Y Eto, MB Drummond, NR Aggarwal, V Sidhaye, LS King |
American journal of respiratory cell and molecular biology | 2012 |
|
Human fibrocytes coexpress thyroglobulin and thyrotropin receptor
R Fernando, S Atkins, N Raychaudhuri, Y Lu, B Li, RS Douglas, TJ Smith |
Proceedings of the National Academy of Sciences | 2012 |
|
The Role of Fibrocytes in Sickle Cell Lung Disease
JJ Field, MD Burdick, MR DeBaun, BA Strieter, L Liu, B Mehrad, CE Rose, J Linden, RM Strieter |
PloS one | 2012 |
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Elevated circulating fibrocyte levels in patients with hypertensive heart disease:
EC Keeley, B Mehrad, R Janardhanan, M Salerno, JR Hunter, MM Burdick, JJ Field, RM Strieter, CM Kramer |
Journal of Hypertension | 2012 |
|
Inhibiting CXCL12 blocks fibrocyte migration and differentiation and attenuates bronchiolitis obliterans in a murine heterotopic tracheal transplant model
DA Harris, Y Zhao, DJ LaPar, A Emaminia, JF Steidle, M Stoler, J Linden, IL Kron, CL Lau |
The Journal of Thoracic and Cardiovascular Surgery | 2012 |
|
Integrin-mediated regulation of TGFβ in fibrosis
NC Henderson, D Sheppard |
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease | 2012 |
|
Treatment with activated protein C (aPC) is protective during the development of myocardial fibrosis: an angiotensin II infusion model in mice
MJ Sopel, NL Rosin, AG Falkenham, M Bezuhly, CT Esmon, TD Lee, RS Liwski, JF Légaré |
PloS one | 2012 |
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Angiotensin II induces skin fibrosis: a novel mouse model of dermal fibrosis
L Stawski, R Han, AM Bujor, M Trojanowska |
Arthritis Research & Therapy | 2012 |
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FcγRI mediates serum amyloid P inhibition of fibrocyte differentiation
JR Crawford, D Pilling, RH Gomer |
Journal of leukocyte biology | 2012 |
|
Activation of p38 Mitogen-Activated Protein Kinase Promotes Peritoneal Fibrosis by Regulating Fibrocytes
S Kokubo, N Sakai, K Furuichi, T Toyama, S Kitajima, T Okumura, K Matsushima, S Kaneko, T Wada |
Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis | 2012 |
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Fibroblast progenitor cells are recruited into the myocardium prior to the development of myocardial fibrosis: Fibrocyte involvement in myocardial fibrosis
M Sopel, A Falkenham, A Oxner, I Ma, TD Lee, JF Légaré |
International Journal of Experimental Pathology | 2012 |
|
Fibrocytes: emerging effector cells in chronic inflammation
H Peng, EL Herzog |
Current Opinion in Pharmacology | 2012 |
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Vein graft neointimal hyperplasia is exacerbated by CXCR4 signaling in vein graft-extrinsic cells
L Zhang, L Brian, NJ Freedman |
Journal of Vascular Surgery | 2012 |
|
Exacerbations in Idiopathic Pulmonary Fibrosis Triggered by Pulmonary and Nonpulmonary Surgery: A Case Series and Comprehensive Review of the Literature
A Ghatol, AP Ruhl, SK Danoff |
Lung | 2012 |
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Recent advances in the pathogenesis and clinical evaluation of pulmonary fibrosis.
Margaritopoulos GA, Romagnoli M, Poletti V, Siafakas NM, Wells AU, Antoniou KM |
2012 | |
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Unravelling the progressive pathophysiology of idiopathic pulmonary fibrosis
Günther A, Korfei M, Mahavadi P, von der Beck D, Ruppert C, Markart P |
European Respiratory Review | 2012 |
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Adenovirus-mediated HIF-1α gene transfer promotes repair of mouse airway allograft microvasculature and attenuates chronic rejection
Xinguo Jiang, Mohammed Khan, Wen Tian, Joshua Beilke, Ramesh Natarajan, Jon Kosek, Merv Yoder, Gregg L. Semenza, Mark Nicolls |
Journal of Clinical Investigation | 2011 |
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FIZZ2/RELM-β induction and role in pulmonary fibrosis
T Liu, HA Baek, H Yu, HJ Lee, BH Park, M Ullenbruch, J Liu, T Nakashima, YY Choi, GD Wu, MJ Chung, SH Phan |
Journal of immunology (Baltimore, Md. : 1950) | 2011 |
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Migration of Fibrocytes in Fibrogenic Liver Injury
D Scholten, D Reichart, YH Paik, J Lindert, J Bhattacharya, CK Glass, DA Brenner, T Kisseleva |
The American Journal of Pathology | 2011 |
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Cadherin-11 contributes to pulmonary fibrosis: potential role in TGF-β production and epithelial to mesenchymal transition
DJ Schneider, M Wu, TT Le, SH Cho, MB Brenner, MR Blackburn, SK Agarwal |
The FASEB Journal | 2011 |
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A Novel Population of Cells Expressing Both Hematopoietic and Mesenchymal Markers Is Present in the Normal Adult Bone Marrow and Is Augmented in a Murine Model of Marrow Fibrosis
M Ohishi, W Ono, N Ono, R Khatri, M Marzia, EK Baker, SH Root, TL Wilson, Y Iwamoto, HM Kronenberg, HL Aguila, LE Purton, E Schipani |
The American Journal of Pathology | 2011 |
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Integrating mechanisms of pulmonary fibrosis
TA Wynn |
Journal of Experimental Medicine | 2011 |
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Effect of Protein Kinase C delta (PKC-δ) Inhibition on the Transcriptome of Normal and Systemic Sclerosis Human Dermal Fibroblasts In Vitro
PJ Wermuth, S Addya, SA Jimenez |
PloS one | 2011 |
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Stem Cells and Cell Therapies in Lung Biology and Lung Diseases
DJ Weiss, I Bertoncello, Z Borok, C Kim, A Panoskaltsis-Mortari, S Reynolds, M Rojas, B Stripp, D Warburton, DJ Prockop |
Proceedings of the American Thoracic Society | 2011 |
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The Chemokine, CCL3, and Its Receptor, CCR1, Mediate Thoracic Radiation–Induced Pulmonary Fibrosis
X Yang, W Walton, DN Cook, X Hua, S Tilley, CA Haskell, R Horuk, AW Blackstock, SL Kirby |
American journal of respiratory cell and molecular biology | 2011 |
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Myofibroblast differentiation and survival in fibrotic disease
K Kis, X Liu, JS Hagood |
Expert Reviews in Molecular Medicine | 2011 |
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Targeting stroma to treat cancers
B Engels, DA Rowley, H Schreiber |
Seminars in Cancer Biology | 2011 |
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CXCL16 recruits bone marrow-derived fibroblast precursors in renal fibrosis
G Chen, SC Lin, J Chen, L He, F Dong, J Xu, S Han, J Du, ML Entman, Y Wang |
Journal of the American Society of Nephrology : JASN | 2011 |
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Fibroblasts expressing the thyrotropin receptor overarch thyroid and orbit in Graves' disease
TJ Smith, DA Padovani-Claudio, Y Lu, N Raychaudhuri, R Fernando, S Atkins, EF Gillespie, AG Gianoukakis, BS Miller, PG Gauger, GM Doherty, RS Douglas |
The Journal of clinical endocrinology and metabolism | 2011 |
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Local apoptosis promotes collagen production by monocyte-derived cells in transforming growth factor β1-induced lung fibrosis
X Peng, SK Mathai, LA Murray, T Russell, R Reilkoff, Q Chen, M Gulati, JA Elias, R Bucala, Y Gan, EL Herzog |
Fibrogenesis & Tissue Repair | 2011 |
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Epithelial-mesenchymal interactions in biliary diseases
L Fabris, M Strazzabosco |
Seminars in liver disease | 2011 |
|
The role of fibrocytes in fibrotic diseases of the lungs and heart
EC Keeley, B Mehrad, RM Strieter |
Fibrogenesis & Tissue Repair | 2011 |
|
Cell Plasticity in Lung Injury and Repair
Z Borok, JA Whitsett, PB Bitterman, VJ Thannickal, DN Kotton, SD Reynolds, MA Krasnow, DW Bianchi, EE Morrisey, BL Hogan, JM Kurie, DC Walker, DC Radisky, SL Nishimura, SM Violette, PW Noble, SD Shapiro, CJ Blaisdell, HA Chapman, J Kiley, D Gail, D Hoshizaki |
Proceedings of the American Thoracic Society | 2011 |
|
Chemokine (C-C motif) ligand 2 mediates direct and indirect fibrotic responses in human and murine cultured fibrocytes
JE Ekert, LA Murray, AM Das, H Sheng, J Giles-Komar, MA Rycyzyn |
Fibrogenesis & Tissue Repair | 2011 |
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Fibrocyte-like cells recruited to the spleen support innate and adaptive immune responses to acute injury or infection
T Kisseleva, M Köckritz-Blickwede, D Reichart, SM McGillvray, G Wingender, M Kronenberg, CK Glass, V Nizet, DA Brenner |
Journal of Molecular Medicine | 2011 |
|
TLR9-induced interferon β is associated with protection from gammaherpesvirus-induced exacerbation of lung fibrosis
TR Luckhardt, SM Coomes, G Trujillo, JS Stoolman, KM Vannella, U Bhan, CA Wilke, TA Moore, GB Toews, C Hogaboam, BB Moore |
Fibrogenesis & Tissue Repair | 2011 |
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Profibrotic potential of Prominin-1+ epithelial progenitor cells in pulmonary fibrosis
P Blyszczuk, D Germano, S Stein, H Moch, CM Matter, B Beck-Schimmer, TF Lüscher, U Eriksson, G Kania |
Respiratory Research | 2011 |
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Age and sex dimorphisms contribute to the severity of bleomycin-induced lung injury and fibrosis
EF Redente, KM Jacobsen, JJ Solomon, AR Lara, S Faubel, RC Keith, PM Henson, GP Downey, DW Riches |
American journal of physiology. Lung cellular and molecular physiology | 2011 |
|
Fibrocytes: emerging effector cells in chronic inflammation
RA Reilkoff, R Bucala, EL Herzog |
Nature Reviews Immunology | 2011 |
|
Functional KCa3.1 K+ channels are required for human fibrocyte migration
G Cruse, SR Singh, SM Duffy, C Doe, R Saunders, CE Brightling, P Bradding |
Journal of Allergy and Clinical Immunology | 2011 |
|
Nicotinic acetylcholine receptor alpha7 subunit is time-dependently expressed in distinct cell types during skin wound healing in mice
YY Fan, TS Yu, T Wang, WW Liu, R Zhao, ST Zhang, WX Ma, JL Zheng, DW Guan |
Histochemistry and Cell Biology | 2011 |
|
High and Low Molecular Weight Hyaluronic Acid Differentially Regulate Human Fibrocyte Differentiation
AS Maharjan, D Pilling, RH Gomer, G Zissel |
PloS one | 2011 |
|
Novel therapeutic approaches for pulmonary fibrosis
A Datta, CJ Scotton, RC Chambers |
British Journal of Pharmacology | 2011 |
|
Progenitor cells in pulmonary vascular remodeling
ME Yeager, MG Frid, KR Stenmark |
Pulmonary circulation | 2011 |
|
Bosentan attenuates right ventricular hypertrophy and fibrosis in normobaric hypoxia model of pulmonary hypertension
G Choudhary, F Troncales, D Martin, EO Harrington, JR Klinger |
The Journal of Heart and Lung Transplantation | 2011 |
|
Remodeling and homeostasis of the extracellular matrix: implications for fibrotic diseases and cancer
TR Cox, JT Erler |
Disease models & mechanisms | 2011 |
|
Altered monocyte and fibrocyte phenotype and function in scleroderma interstitial lung disease: reversal by caveolin-1 scaffolding domain peptide
E Tourkina, M Bonner, J Oates, A Hofbauer, M Richard, S Znoyko, RP Visconti, J Zhang, CM Hatfield, RM Silver, S Hoffman |
Fibrogenesis & Tissue Repair | 2011 |
|
Fibrocytes and the tissue niche in lung repair
A Andersson-Sjöland, K Nihlberg, L Eriksson, L Bjermer, G Westergren-Thorsson |
Respiratory Research | 2011 |
|
The pivotal role of fibrocytes and mast cells in mediating fibrotic reactions to biomaterials
PT Thevenot, DW Baker, H Weng, MW Sun, L Tang |
Biomaterials | 2011 |
|
Central Nervous System Fibrosis Is Associated with Fibrocyte-Like Infiltrates
A Aldrich, T Kielian |
The American Journal of Pathology | 2011 |
|
C/EBPβ-Thr217 Phosphorylation Signaling Contributes to the Development of Lung Injury and Fibrosis in Mice
M Buck, M Chojkier |
PloS one | 2011 |
|
Stem cell therapy for idiopathic pulmonary fibrosis: a protocol proposal
A Tzouvelekis, G Koliakos, P Ntolios, I Baira, E Bouros, A Oikonomou, A Zissimopoulos, G Kolios, D Kakagia, V Paspaliaris, I Kotsianidis, M Froudarakis, D Bouros |
Journal of Translational Medicine | 2011 |
|
CCR2 mediates the uptake of bone marrow-derived fibroblast precursors in angiotensin II-induced cardiac fibrosis
J Xu, SC Lin, J Chen, Y Miao, GE Taffet, ML Entman, Y Wang |
American journal of physiology. Heart and circulatory physiology | 2011 |
|
Immunology of fibrotic lung disease: managing infections whilst preventing autoimmunity?
T Hügle |
Journal of inflammation research | 2011 |
|
Hypoxic pulmonary hypertension in mice with constitutively active platelet-derived growth factor receptor-β
BK Dahal, R Heuchel, SS Pullamsetti, J Wilhelm, HA Ghofrani, N Weissmann, W Seeger, F Grimminger, RT Schermuly |
Pulmonary circulation | 2011 |
|
Mesenchymal stromal cell mutations and wound healing contribute to the etiology of desmoid tumors
AM Carothers, H Rizvi, RM Hasson, YI Heit, JS Davids, MM Bertagnolli, NL Cho |
Cancer research | 2011 |
|
Role of semaphorin 7a signaling in transforming growth factor β1-induced lung fibrosis and scleroderma-related interstitial lung disease
Y Gan, R Reilkoff, X Peng, T Russell, Q Chen, SK Mathai, R Homer, M Gulati, J Siner, J Elias, R Bucala, E Herzog |
Arthritis & Rheumatism | 2011 |
|
Circulating Fibrocytes Correlate With Bronchiolitis Obliterans Syndrome Development After Lung Transplantation: A Novel Clinical Biomarker
DJ LaPar, MD Burdick, A Emaminia, DA Harris, BA Strieter, L Liu, M Robbins, IL Kron, RM Strieter, CL Lau |
The Annals of Thoracic Surgery | 2011 |
|
CD4 + T Cells and Complement Independently Mediate Graft Ischemia in the Rejection of Mouse Orthotopic Tracheal Transplants
MA Khan, X Jiang, G Dhillon, J Beilke, VM Holers, C Atkinson, S Tomlinson, MR Nicolls |
Circulation research | 2011 |
|
Role for Circulating Osteogenic Precursor Cells in Aortic Valvular Disease
KP Egan, JH Kim, ER Mohler, RJ Pignolo |
Arteriosclerosis, thrombosis, and vascular biology | 2011 |
|
Antifibrotic activities of pirfenidone in animal models.
Schaefer CJ, Ruhrmund DW, Pan L, Seiwert SD, Kossen K |
European respiratory review : an official journal of the European Respiratory Society | 2011 |
|
The von Hippel-Lindau Chuvash mutation promotes pulmonary hypertension and fibrosis in mice
Michele Hickey, Theresa Richardson, Tao Wang, Matias Mosqueira, Evguenia Arguiri, Hongwei Yu, Qian-Chun Yu, Charalambos Solomides, Edward Morrisey, Tejvir Khurana, Melpo Christofidou-Solomidou, M. Celeste Simon |
Journal of Clinical Investigation | 2010 |
|
Inhibition of Pulmonary Fibrosis by CXCL10 Requires Glycosaminoglycan Binding and Syndecan-4
Dianhua Jiang, Jiurong Liang, Gabriele Campanella, Rishu Guo, Shuang Yu, Ting Xie, Ningshan Liu, Yoosun Jung, Robert Homer, Eric B. Meltzer, Yuejuan Li, Andrew Tager, Paul Goetinck, Andrew D Luster, Paul W. Noble |
Journal of Clinical Investigation | 2010 |
|
Loss of Negative Feedback Control of Nuclear Factor-κB2 Activity in Lymphocytes Leads to Fatal Lung Inflammation
L Yang, H Cui, Z Wang, B Zhang, J Ding, L Liu, HF Ding |
The American Journal of Pathology | 2010 |
|
Comprehensive Physiology
R Terjung |
Comprehensive Physiology | 2010 |
|
Inhibitory effect of CXC chemokine receptor 4 antagonist AMD3100 on bleomycin induced murine pulmonary fibrosis
JS Song, CM Kang, HH Kang, HK Yoon, YK Kim, KH Kim, HS Moon, SH Park |
Experimental & molecular medicine | 2010 |
|
New concepts of IL-10-induced lung fibrosis: fibrocyte recruitment and M2 activation in a CCL2/CCR2 axis
L Sun, MC Louie, KM Vannella, CA Wilke, AM LeVine, BB Moore, TP Shanley |
AJP Lung Cellular and Molecular Physiology | 2010 |
|
Intramyocardial fibroblast myocyte communication
R Kakkar, RT Lee |
Circulation research | 2010 |
|
MCP1 directs trafficking of hematopoietic stem cell-derived fibroblast precursors in solid tumor
RS Abangan, CR Williams, M Mehrotra, JD Duncan, AC Larue |
The American Journal of Pathology | 2010 |
|
Selective Enhancement of Donor Hematopoietic Cell Engraftment by the CXCR4 Antagonist AMD3100 in a Mouse Transplantation Model
Y Kang, BJ Chen, D DeOliveira, J Mito, NJ Chao, A Leri |
PloS one | 2010 |
|
Autocrine production of TGF-beta1 promotes myofibroblastic differentiation of neonatal lung mesenchymal stem cells
AP Popova, PD Bozyk, AM Goldsmith, MJ Linn, J Lei, JK Bentley, MB Hershenson |
American journal of physiology. Lung cellular and molecular physiology | 2010 |
|
Repetitive intratracheal bleomycin models several features of idiopathic pulmonary fibrosis
AL Degryse, H Tanjore, XC Xu, VV Polosukhin, BR Jones, FB McMahon, LA Gleaves, TS Blackwell, WE Lawson |
AJP Lung Cellular and Molecular Physiology | 2010 |
|
Fibrocyte activation in rheumatoid arthritis
CL Galligan, KA Siminovitch, EC Keystone, V Bykerk, OD Perez, EN Fish |
Rheumatology (Oxford, England) | 2010 |
|
Serum amyloid P therapeutically attenuates murine bleomycin-induced pulmonary fibrosis via its effects on macrophages
LA Murray, R Rosada, AP Moreira, A Joshi, MS Kramer, DP Hesson, RL Argentieri, S Mathai, M Gulati, EL Herzog, CM Hogaboam |
PloS one | 2010 |
|
Bone marrow-derived cells contribute to fibrosis in the chronically failing heart
PY Chu, J Mariani, S Finch, JR McMullen, J Sadoshima, T Marshall, DM Kaye |
The American Journal of Pathology | 2010 |
|
Hepatocyte growth factor in lung repair and pulmonary fibrosis
RA Panganiban, RM Day |
Acta Pharmacologica Sinica | 2010 |
|
Fibrocytes in health and disease
EL Herzog, R Bucala |
Experimental Hematology | 2010 |
|
The Pathogenesis of Systemic Sclerosis Revisited
M Geyer, U Müller-Ladner |
Clinical Reviews in Allergy & Immunology | 2010 |
|
Viral infection and aging as cofactors for the development of pulmonary fibrosis
PK Naik, BB Moore |
Expert Review of Respiratory Medicine | 2010 |
|
Involvement of bone-marrow-derived cells in kidney fibrosis
T Wada, N Sakai, Y Sakai, K Matsushima, S Kaneko, K Furuichi |
Clinical and Experimental Nephrology | 2010 |
|
Concise review: bone marrow-derived stem/progenitor cells in cutaneous repair and regeneration
Y Wu, RC Zhao, EE Tredget |
Stem Cells | 2010 |
|
T regulatory cells and attenuated bleomycin-induced fibrosis in lungs of CCR7-/- mice
G Trujillo, AJ Hartigan, CM Hogaboam |
Fibrogenesis & Tissue Repair | 2010 |
|
Inhibition of NF-kappaB signaling reduces virus load and gammaherpesvirus-induced pulmonary fibrosis
LT Krug, E Torres-González, Q Qin, D Sorescu, M Rojas, A Stecenko, SH Speck, AL Mora |
The American Journal of Pathology | 2010 |
|
Caveolin-1 regulates leucocyte behaviour in fibrotic lung disease
E Tourkina, M Richard, J Oates, A Hofbauer, M Bonner, P Gööz, R Visconti, J Zhang, S Znoyko, CM Hatfield, RM Silver, S Hoffman |
Annals of the rheumatic diseases | 2010 |
|
Distinct types of fibrocyte can differentiate from mononuclear cells in the presence and absence of serum
SJ Curnow, M Fairclough, C Schmutz, S Kissane, AK Denniston, K Nash, CD Buckley, JM Lord, M Salmon |
PloS one | 2010 |
|
Reactive response of fibrocytes to vocal fold mucosal injury in rat
C Ling, M Yamashita, J Zhang, DM Bless, NV Welham |
Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society | 2010 |
|
Stem cells as vectors for antitumour therapy
MR Loebinger, SM Janes |
Thorax | 2010 |
|
Monocytic fibroblast precursors mediate fibrosis in angiotensin-II-induced cardiac hypertrophy
SB Haudek, J Cheng, J Du, Y Wang, J Hermosillo-Rodriguez, JA Trial, GE Taffet, ML Entman |
Journal of Molecular and Cellular Cardiology | 2010 |
|
Improved serum-free culture conditions for spleen-derived murine fibrocytes
JR Crawford, D Pilling, RH Gomer |
Journal of Immunological Methods | 2010 |
|
Workshop on Idiopathic Pulmonary Fibrosis in Older Adults
RJ Castriotta, BA Eldadah, WM Foster, JB Halter, WR Hazzard, JP Kiley, TE King, FM Horne, SG Nayfield, HY Reynolds, KE Schmader, GB Toews, KP High |
Chest | 2010 |
|
The contribution of L-selectin to airway hyperresponsiveness in chronic allergic airways disease.
Royce SG, Lee M, Tang ML |
Journal of asthma and allergy | 2010 |
|
Circulating osteogenic precursor cells.
Pignolo RJ, Shore EM |
Critical reviews in eukaryotic gene expression | 2010 |
|
Fibrogenesis
Munger JS, Rom WN |
2010 | |
|
WISP1, a matricellular protein of the CCN family, is a novel mediator of pulmonary fibrosis
Melanie Königshoff, Monika Kramer, Nisha Balsara, Jochen Wilhelm, Oana Veronica Amarie, Andreas Jahn, Frank Rose, Ludger Fink, Werner Seeger, Liliana Schaefer, Andreas Günther, Oliver Eickelberg |
Journal of Clinical Investigation | 2009 |
|
Circulating Osteogenic Precursor Cells in Heterotopic Bone Formation
RK Suda, PC Billings, KP Egan, JH Kim, R McCarrick-Walmsley, DL Glaser, DL Porter, EM Shore, RJ Pignolo |
Stem Cells | 2009 |
|
Emerging Concepts in the Pathogenesis of Lung Fibrosis
WD Hardie, SW Glasser, JS Hagood |
The American Journal of Pathology | 2009 |
|
Pulmonary surfactant: an immunological perspective
ZC Chroneos, Z Sever-Chroneos, VL Shepherd |
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology | 2009 |
|
Use of senescence-accelerated mouse model in bleomycin-induced lung injury suggests that bone marrow-derived cells can alter the outcome of lung injury in aged mice
J Xu, ET Gonzalez, SS Iyer, V Mac, AL Mora, RL Sutliff, A Reed, KL Brigham, P Kelly, M Rojas |
The journals of gerontology. Series A, Biological sciences and medical sciences | 2009 |
|
The pro-fibrotic factor IGFBP-5 induces lung fibroblast and mononuclear cell migration
H Yasuoka, Y Yamaguchi, CA Feghali-Bostwick |
American journal of respiratory cell and molecular biology | 2009 |
|
Determinants of initiation and progression of idiopathic pulmonary fibrosis
RM KOTTMANN, CM HOGAN, RP PHIPPS, PJ SIME |
Respirology | 2009 |
|
New mechanisms of pulmonary fibrosis
RM Strieter, B Mehrad |
Chest | 2009 |
|
Antifibrosis: To Reverse the Irreversible
Z Paz, Y Shoenfeld |
Clinical Reviews in Allergy & Immunology | 2009 |
|
Pulmonary fibrosis: pathogenesis, etiology and regulation
MS Wilson, TA Wynn |
Mucosal Immunology | 2009 |
|
The role of circulating mesenchymal progenitor cells (fibrocytes) in the pathogenesis of pulmonary fibrosis
RM Strieter, EC Keeley, MA Hughes, MD Burdick, B Mehrad |
Journal of leukocyte biology | 2009 |
|
Contribution of epithelial-derived fibroblasts to bleomycin-induced lung fibrosis
H Tanjore, XC Xu, VV Polosukhin, AL Degryse, B Li, W Han, TP Sherrill, D Plieth, EG Neilson, TS Blackwell, WE Lawson |
American journal of respiratory and critical care medicine | 2009 |
|
Fibrocytes: bringing new insights into mechanisms of inflammation and fibrosis
EC Keeley, B Mehrad, RM Strieter |
The International Journal of Biochemistry & Cell Biology | 2009 |
|
Fibrocyte CXCR4 regulation as a therapeutic target in pulmonary fibrosis
B Mehrad, MD Burdick, RM Strieter |
The International Journal of Biochemistry & Cell Biology | 2009 |
|
CD4+ T cells control the differentiation of Gr1+ monocytes into fibrocytes
M Niedermeier, B Reich, MR Gomez, A Denzel, K Schmidbauer, N Göbel, Y Talke, F Schweda, M Mack |
Proceedings of the National Academy of Sciences | 2009 |
|
Treadmill running exercise results in the presence of numerous myofibroblasts in mouse patellar tendons
M Szczodry, J Zhang, C Lim, HL Davitt, T Yeager, FH Fu, JH Wang |
Journal of Orthopaedic Research | 2009 |
|
Gene Expression Profiling of Pulmonary Fibrosis Identifies Twist1 as an Antiapoptotic Molecular “Rectifier” of Growth Factor Signaling
RS Bridges, D Kass, K Loh, C Glackin, AC Borczuk, S Greenberg |
The American Journal of Pathology | 2009 |
|
Systemic Inhibition of NF-κB Activation Protects from Silicosis
MD Giuseppe, F Gambelli, GW Hoyle, G Lungarella, SM Studer, T Richards, S Yousem, K McCurry, J Dauber, N Kaminski, G Leikauf, LA Ortiz, PJ Barnes |
PloS one | 2009 |
|
Identification of Markers that Distinguish Monocyte-Derived Fibrocytes from Monocytes, Macrophages, and Fibroblasts
D Pilling, T Fan, D Huang, B Kaul, RH Gomer, L Rénia |
PloS one | 2009 |
|
CXCR4 and Matrix Metalloproteinase-1 Are Elevated in Breast Carcinoma–Associated Fibroblasts and in Normal Mammary Fibroblasts Exposed to Factors Secreted by Breast Cancer Cells
SM Eck, AL Côté, WD Winkelman, CE Brinckerhoff |
Molecular cancer research : MCR | 2009 |
|
Development, repair and fibrosis: What is common and why it matters
W Shi, J Xu, D Warburton |
Respirology | 2009 |
|
Latent herpesvirus infection augments experimental pulmonary fibrosis
KM Vannella, TR Luckhardt, CA Wilke, LF van Dyk, GB Toews, BB Moore |
American journal of respiratory and critical care medicine | 2009 |
|
Improved serum-free culture conditions for the differentiation of human and murine fibrocytes
D Pilling, V Vakil, RH Gomer |
Journal of Immunological Methods | 2009 |
|
Human circulating fibrocytes have the capacity to differentiate osteoblasts and chondrocytes
YH Choi, MD Burdick, RM Strieter |
The International Journal of Biochemistry & Cell Biology | 2009 |
|
CXCR4 expression on circulating pan-cytokeratin positive cells is associated with survival in patients with advanced non-small cell lung cancer
KL Reckamp, RA Figlin, MD Burdick, SM Dubinett, RM Elashoff, RM Strieter |
BMC Cancer | 2009 |
|
Detection of fibrocytes in human skin wounds and its application for wound age determination
Y Ishida, A Kimura, T Takayasu, W Eisenmenger, T Kondo |
International Journal of Legal Medicine | 2009 |
|
Podocytes produce homeostatic chemokine stromal cell-derived factor-1/CXCL12, which contributes to glomerulosclerosis, podocyte loss and albuminuria in a mouse model of type 2 diabetes
SG Sayyed, H Hägele, OP Kulkarni, K Endlich, S Segerer, D Eulberg, S Klussmann, HJ Anders |
Diabetologia | 2009 |
|
Chemokines and cardiac fibrosis.
Dobaczewski M, Frangogiannis NG |
Frontiers in bioscience (Scholar edition) | 2009 |
|
Wnt pathway in pulmonary fibrosis in the bleomycin mouse model.
Liu L, Carron B, Yee HT, Yie TA, Hajjou M, Rom W |
Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer | 2009 |
|
Fibrocyte localization to the airway smooth muscle is a feature of asthma
R Saunders, S Siddiqui, D Kaur, C Doe, A Sutcliffe, F Hollins, P Bradding, A Wardlaw, CE Brightling |
Journal of Allergy and Clinical Immunology | 2008 |
|
Exacerbation of established pulmonary fibrosis in a murine model by gammaherpesvirus
TR McMillan, BB Moore, JB Weinberg, KM Vannella, WB Fields, PJ Christensen, LF van Dyk, GB Toews |
American journal of respiratory and critical care medicine | 2008 |
|
The synthetic peroxisome proliferator-activated receptor-gamma agonist ciglitazone attenuates neuroinflammation and accelerates encapsulation in bacterial brain abscesses
T Kielian, MM Syed, S Liu, NK Phulwani, N Phillips, G Wagoner, PD Drew, N Esen |
Journal of immunology (Baltimore, Md. : 1950) | 2008 |
|
Lung fibroblast repair functions in patients with chronic obstructive pulmonary disease are altered by multiple mechanisms
S Togo, O Holz, X Liu, H Sugiura, K Kamio, X Wang, S Kawasaki, Y Ahn, K Fredriksson, CM Skold, KC Mueller, D Branscheid, L Welker, H Watz, H Magnussen, SI Rennard |
American journal of respiratory and critical care medicine | 2008 |
|
Development of pulmonary fibrosis through a pathway involving the transcription factor Fra-2/AP-1
R Eferl, P Hasselblatt, M Rath, H Popper, R Zenz, V Komnenovic, MH Idarraga, L Kenner, EF Wagner |
Proceedings of the National Academy of Sciences | 2008 |
|
Macrophage roles following myocardial infarction
JM Lambert, EF Lopez, ML Lindsey |
International Journal of Cardiology | 2008 |
|
Stem cells in airway smooth muscle: state of the art
J Murphy, R Summer, A Fine |
Proceedings of the American Thoracic Society | 2008 |
|
The immune system and cardiac repair
NG Frangogiannis |
Pharmacological research : the official journal of the Italian Pharmacological Society | 2008 |
|
Cellular and molecular mechanisms of fibrosis
TA Wynn |
The Journal of Pathology | 2008 |
|
Methods for studying stem cells: Adult stem cells for lung repair
U Martin |
Methods (San Diego, Calif.) | 2008 |
|
What differentiates normal lung repair and fibrosis? Inflammation, resolution of repair, and fibrosis
RM Strieter |
Proceedings of the American Thoracic Society | 2008 |
|
Stem cells and cell therapies in lung biology and lung diseases
DJ Weiss, JK Kolls, LA Ortiz, A Panoskaltsis-Mortari, DJ Prockop |
Proceedings of the American Thoracic Society | 2008 |
|
Idiopathic pulmonary fibrosis
EB Meltzer, PW Noble |
Orphanet Journal of Rare Diseases | 2008 |
|
Biology of fibroblasts and myofibroblasts
SH Phan |
Proceedings of the American Thoracic Society | 2008 |
|
Adenosine A2A Receptor Blockade or Deletion Diminishes Fibrocyte Accumulation in the Skin in a Murine Model of Scleroderma, Bleomycin-induced Fibrosis
M Katebi, P Fernandez, ES Chan, BN Cronstein |
Inflammation | 2008 |
|
Retention of human bone marrow-derived cells in murine lungs following bleomycin-induced lung injury
JM Liebler, C Lutzko, A Banfalvi, D Senadheera, N Aghamohammadi, ED Crandall, Z Borok |
American journal of physiology. Lung cellular and molecular physiology | 2008 |
|
Ectopic lymphoid tissues and local immunity
DM Carragher, J Rangel-Moreno, TD Randall |
Seminars in Immunology | 2008 |
|
Pivotal Advance: Th-1 cytokines inhibit, and Th-2 cytokines promote fibrocyte differentiation
DD Shao, R Suresh, V Vakil, RH Gomer, D Pilling |
Journal of leukocyte biology | 2008 |
|
Knowns and unknowns of the alveolus
EL Herzog, AR Brody, TV Colby, R Mason, MC Williams |
Proceedings of the American Thoracic Society | 2008 |
|
Mesenchymal stem cells as vectors for lung disease
MR Loebinger, EK Sage, SM Janes |
Proceedings of the American Thoracic Society | 2008 |
|
Stem cells and cell therapies for cystic fibrosis and other lung diseases
DJ Weiss |
Pulmonary Pharmacology & Therapeutics | 2008 |
|
The bleomycin animal model: A useful tool to investigate treatment options for idiopathic pulmonary fibrosis?
A Moeller, K Ask, D Warburton, J Gauldie, M Kolb |
The International Journal of Biochemistry & Cell Biology | 2008 |
|
Immune Interactions in Hepatic Fibrosis
AP Holt, M Salmon, CD Buckley, DH Adams |
Clinics in Liver Disease | 2008 |
|
Unique Attributes of Orbital Fibroblasts and Global Alterations in IGF-1 Receptor Signaling Could Explain Thyroid-Associated Ophthalmopathy
TJ Smith, CC Tsai, MJ Shih, S Tsui, B Chen, R Han, V Naik, CS King, C Press, S Kamat, RA Goldberg, RP Phipps, RS Douglas, AG Gianoukakis |
Thyroid | 2008 |
|
Viruses as co-factors for the initiation or exacerbation of lung fibrosis
KM Vannella, BB Moore |
Fibrogenesis & Tissue Repair | 2008 |
|
Attenuation of obliterative bronchiolitis by a CXCR4 antagonist in the murine heterotopic tracheal transplant model
J Xu, E Torres, AL Mora, H Shim, A Ramirez, D Neujahr, KL Brigham, M Rojas |
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation | 2008 |
|
Serum amyloid P inhibits dermal wound healing
B Naik-Mathuria, D Pilling, JR Crawford, AN Gay, CW Smith, RH Gomer, OO Olutoye |
Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society | 2008 |
|
Circulating angiogenic precursors in idiopathic pulmonary arterial hypertension
K Asosingh, MA Aldred, A Vasanji, J Drazba, J Sharp, C Farver, SA Comhair, W Xu, L Licina, L Huang, B Anand-Apte, MC Yoder, RM Tuder, SC Erzurum |
The American Journal of Pathology | 2008 |
|
Gene expression profiling demonstrates a novel role for foetal fibrocytes and the umbilical vessels in human fetoplacental development
JS Kim, R Romero, AL Tarca, C LaJeunesse, YM Han, MJ Kim, YL Suh, S Draghici, P Mittal, F Gotsch, JP Kusanovic, S Hassan, CJ Kim |
Journal of Cellular and Molecular Medicine | 2008 |
|
Thrombin Induces Fibroblast CCL2/JE Production and Release via Coupling of PAR1 to G q and Cooperation between ERK1/2 and Rho Kinase Signaling Pathways
X Deng, PF Mercer, CJ Scotton, A Gilchrist, RC Chambers |
Molecular biology of the cell | 2008 |
|
IL-1R1/MyD88 Signaling and Inflammasome are Essential in Bleomycin Induced Pulmonary Inflammation and Fibrosis
Pamela Gasse, Caroline Mary, Isabelle Guenon, Nicolas Noulin, Sabine Charron, Silvia Schnyder-Candrian, Bruno Schnyder, Shizuo Akira, Valérie F. J. Quesniaux, Vincent Lagente, Bernhard Ryffel and Isabelle Couillin. |
Journal of Clinical Investigation | 2007 |
|
Infectious Disease, the Innate Immune Response, and Fibrosis
Alessia Meneghin, MD and Cory M. Hogaboam, PhD |
Journal of Clinical Investigation | 2007 |
|
The Role of CXC Chemokines in Pulmonary Fibrosis
Robert M. Strieter1, Brigitte N. Gomperts2, and Michael P. Keane3 |
Journal of Clinical Investigation | 2007 |
|
SYSTEMIC SCLEROSIS: A PROTOTYPIC MULTISYSTEM FIBROTIC DISORDER
John Varga and David Abraham |
Journal of Clinical Investigation | 2007 |
|
Common and Unique Mechanisms Regulate Fibrosis in Various Fibroproliferative Diseases
Thomas A. Wynn |
Journal of Clinical Investigation | 2007 |
|
Bone-marrow-derived stem cells — our key to longevity?
MZ Ratajczak, EK Zuba-Surma, B Machalinski, M Kucia |
Journal of Applied Genetics | 2007 |
|
A new murine model for bronchiolitis obliterans post-bone marrow transplant
A Panoskaltsis-Mortari, KV Tram, AP Price, CH Wendt, BR Blazar |
American journal of respiratory and critical care medicine | 2007 |
|
Chemokines and their receptors as potential targets for the treatment of asthma
C Palmqvist, AJ Wardlaw, P Bradding |
British Journal of Pharmacology | 2007 |
|
Role of the SDF-1/CXCR4 axis in the pathogenesis of lung injury and fibrosis
J Xu, A Mora, H Shim, A Stecenko, KL Brigham, M Rojas |
American journal of respiratory cell and molecular biology | 2007 |
|
New Insights into the Pathogenesis and Treatment of Idiopathic Pulmonary Fibrosis: A Potential Role for Stem Cells in the Lung Parenchyma and Implications for Therapy
M Gharaee-Kermani, MR Gyetko, B Hu, SH Phan |
Pharmaceutical Research | 2007 |
|
Fibroblasts as novel therapeutic targets in chronic inflammation
SJ Flavell, TZ Hou, S Lax, AD Filer, M Salmon, CD Buckley |
British Journal of Pharmacology | 2007 |
|
Essential roles of the CC chemokine ligand 3-CC chemokine receptor 5 axis in bleomycin-induced pulmonary fibrosis through regulation of macrophage and fibrocyte infiltration
Y Ishida, A Kimura, T Kondo, T Hayashi, M Ueno, N Takakura, K Matsushima, N Mukaida |
The American Journal of Pathology | 2007 |
|
Decreased asbestos-induced lung inflammation and fibrosis after radiation and bone marrow transplant
J Levis, R Loi, KJ Butnor, P Vacek, C Steele, BT Mossman, DJ Weiss |
American journal of respiratory cell and molecular biology | 2007 |
|
Muscle fatigue: MK2 signaling and myofibroblast differentiation
JS Hagood, MA Olman |
American journal of respiratory cell and molecular biology | 2007 |
|
Engraftment of bone marrow progenitor cells in a rat model of asbestos-induced pulmonary fibrosis
JL Spees, DA Pociask, DE Sullivan, MJ Whitney, JA Lasky, DJ Prockop, AR Brody |
American journal of respiratory and critical care medicine | 2007 |
|
Circulating progenitor cells in chronic lung disease
B Mehrad, MP Keane, BN Gomperts, RM Strieter |
Expert Review of Respiratory Medicine | 2007 |
|
The Myofibroblast
B Hinz, SH Phan, VJ Thannickal, A Galli, ML Bochaton-Piallat, G Gabbiani |
The American Journal of Pathology | 2007 |
|
Isolation of an Adult Mouse Lung Mesenchymal Progenitor Cell Population
R Summer, K Fitzsimmons, D Dwyer, J Murphy, A Fine |
American journal of respiratory cell and molecular biology | 2007 |
|
Using mouse genomics to understand idiopathic interstitial fibrosis
DM Brass, J Tomfohr, IV Yang, DA Schwartz |
Proceedings of the American Thoracic Society | 2007 |
|
Acute Exacerbations of Idiopathic Pulmonary Fibrosis
HR Collard, BB Moore, KR Flaherty, KK Brown, RJ Kaner, TE King, JA Lasky, JE Loyd, I Noth, MA Olman, G Raghu, J Roman, JH Ryu, DA Zisman, GW Hunninghake, TV Colby, JJ Egan, DM Hansell, T Johkoh, N Kaminski, DS Kim, Y Kondoh, DA Lynch, J Müller-Quernheim, JL Myers, AG Nicholson, M Selman, GB Toews, AU Wells, FJ Martinez |
American journal of respiratory and critical care medicine | 2007 |
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Reduction of Bleomycin-Induced Pulmonary Fibrosis by Serum Amyloid P
Pilling D, Roife D, Wang M, Ronkainen SD, Crawford JR, Travis EL, Gomer RH |
Journal of immunology (Baltimore, Md. : 1950) | 2007 |
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Cysteinyl leukotrienes are autocrine and paracrine regulators of fibrocyte function.
Vannella KM, McMillan TR, Charbeneau RP, Wilke CA, Thomas PE, Toews GB, Peters-Golden M, Moore BB |
Journal of immunology (Baltimore, Md. : 1950) | 2007 |
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A homing mechanism for bone marrow derived progenitor cell recruitment to the neovasculature
Hui Jin, Aparna Aiyer, Jingmei Su, Per Borgstrom, Dwayne Stupack, Martin Friedlander and Judy Varner |
Journal of Clinical Investigation | 2006 |
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Bone morphogenetic protein-4 inhibitor gremlin is overexpressed in idiopathic pulmonary fibrosis
K Koli, M Myllärniemi, K Vuorinen, K Salmenkivi, MJ Ryynänen, VL Kinnula, J Keski-Oja |
The American Journal of Pathology | 2006 |
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Soluble TNF mediates the transition from pulmonary inflammation to fibrosis
N Oikonomou, V Harokopos, J Zalevsky, C Valavanis, A Kotanidou, DE Szymkowski, G Kollias, V Aidinis |
PloS one | 2006 |
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Gene expression profiling of familial and sporadic interstitial pneumonia
IV Yang, LH Burch, MP Steele, JD Savov, JW Hollingsworth, E McElvania-Tekippe, KG Berman, MC Speer, TA Sporn, KK Brown, MI Schwarz, DA Schwartz |
American journal of respiratory and critical care medicine | 2006 |
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Alveolar epithelial cell mesenchymal transition develops in vivo during pulmonary fibrosis and is regulated by the extracellular matrix
KK Kim, MC Kugler, PJ Wolters, L Robillard, MG Galvez, AN Brumwell, D Sheppard, HA Chapman |
Proceedings of the National Academy of Sciences | 2006 |
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Stromal derived factor-1 (SDF-1/CXCL12) and CXCR4 in renal cell carcinoma metastasis
J Pan, J Mestas, MD Burdick, RJ Phillips, GV Thomas, K Reckamp, JA Belperio, RM Strieter |
Molecular Cancer | 2006 |
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Epithelial-mesenchymal interactions in pulmonary fibrosis
JC Horowitz, VJ Thannickal |
Seminars in respiratory and critical care medicine | 2006 |
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Aggregated IgG inhibits the differentiation of human fibrocytes
D Pilling |
Journal of leukocyte biology | 2006 |
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Smad3 signaling involved in pulmonary fibrosis and emphysema
J Gauldie, M Kolb, K Ask, G Martin, P Bonniaud, D Warburton |
Proceedings of the American Thoracic Society | 2006 |
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Focal interstitial CC chemokine receptor 7 (CCR7) expression in idiopathic interstitial pneumonia
ES Choi, EM Pierce, C Jakubzick, KJ Carpenter, SL Kunkel, H Evanoff, FJ Martinez, KR Flaherty, BB Moore, GB Toews, TV Colby, EA Kazerooni, BH Gross, WD Travis, CM Hogaboam |
Journal of clinical pathology | 2006 |
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Targeting the stromal microenvironment in chronic inflammation
A Filer, C Pitzalis, CD Buckley |
Current Opinion in Pharmacology | 2006 |
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Secondary lymphoid tissue chemokine (SLC/CCL21)/CCR7 signaling regulates fibrocytes in renal fibrosis
N Sakai, T Wada, H Yokoyama, M Lipp, S Ueha, K Matsushima, S Kaneko |
Proceedings of the National Academy of Sciences | 2006 |
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Angiogenesis in interstitial lung diseases: a pathogenetic hallmark or a bystander?
A Tzouvelekis, S Anevlavis, D Bouros |
Respiratory Research | 2006 |
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Tissue fibrocytes in patients with mild asthma: a possible link to thickness of reticular basement membrane?
K Nihlberg, K Larsen, A Hultgårdh-Nilsson, A Malmström, L Bjermer, G Westergren-Thorsson |
Respiratory Research | 2006 |
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Airway epithelial stem cells and the pathophysiology of chronic obstructive pulmonary disease
SH Randell |
Proceedings of the American Thoracic Society | 2006 |
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The extrapulmonary origin of fibroblasts: stem/progenitor cells and beyond
VN Lama, SH Phan |
Proceedings of the American Thoracic Society | 2006 |
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Hypoxia-induced pulmonary vascular remodeling requires recruitment of circulating mesenchymal precursors of a monocyte/macrophage lineage
MG Frid, JA Brunetti, DL Burke, TC Carpenter, NJ Davie, JT Reeves, MT Roedersheimer, N Rooijen, KR Stenmark |
The American Journal of Pathology | 2006 |
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The role of circulating fibrocytes in fibrosis
TE Quan, SE Cowper, R Bucala |
Current Rheumatology Reports | 2006 |
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The Role of CCL12 in the Recruitment of Fibrocytes and Lung Fibrosis
BB Moore, L Murray, A Das, CA Wilke, AB Herrygers, GB Toews |
American journal of respiratory cell and molecular biology | 2006 |
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Insulin-like growth factor-binding protein-5 induces pulmonary fibrosis and triggers mononuclear cellular infiltration
H Yasuoka, Z Zhou, JM Pilewski, TD Oury, AM Choi, CA Feghali-Bostwick |
The American Journal of Pathology | 2006 |
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β-Catenin in the Fibroproliferative Response to Acute Lung Injury
IS Douglas, FD Valle, RA Winn, NF Voelkel |
American journal of respiratory cell and molecular biology | 2006 |
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IDIOPATHIC PULMONARY FIBROSIS: NEW CONCEPTS IN PATHOGENESIS AND IMPLICATIONS FOR DRUG THERAPY
Horowitz JC, Thannickal VJ |
Treatments in Respiratory Medicine | 2006 |
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TNF-alpha sensitizes normal and fibrotic human lung fibroblasts to Fas-induced apoptosis
SK Frankel, GP Cosgrove, SI Cha, CD Cool, MW Wynes, BL Edelman, KK Brown, DW Riches |
American journal of respiratory cell and molecular biology | 2005 |
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Modulation of Prosurvival Signaling in Fibroblasts by a Protein Kinase Inhibitor Protects against Fibrotic Tissue Injury
R Vittal, JC Horowitz, BB Moore, H Zhang, FJ Martinez, GB Toews, TJ Standiford, VJ Thannickal |
The American Journal of Pathology | 2005 |
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Constitutive activation of prosurvival signaling in alveolar mesenchymal cells isolated from patients with nonresolving acute respiratory distress syndrome
JC Horowitz, Z Cui, TA Moore, TR Meier, RC Reddy, GB Toews, TJ Standiford, VJ Thannickal |
American journal of physiology. Lung cellular and molecular physiology | 2005 |
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Chemokine-mediated angiogenesis: an essential link in the evolution of airway fibrosis?
IS Douglas, MR Nicolls |
Journal of Clinical Investigation | 2005 |
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Stromal remodeling and SPARC (secreted protein acid rich in cysteine) expression in invasive ductal carcinomas of the breast
PJ Barth, R Moll, A Ramaswamy |
Virchows Archiv | 2005 |
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Bone Marrow-Derived Cells in the Pathogenesis of Lung Fibrosis
B Moore, V Thannickal, G Toews |
Current respiratory medicine reviews | 2005 |
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A stromal address code defined by fibroblasts
G Parsonage, AD Filer, O Haworth, GB Nash, GE Rainger, M Salmon, CD Buckley |
Trends in Immunology | 2005 |
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Failure of Bone Marrow to Reconstitute Lung Epithelium
DN Kotton, AJ Fabian, RC Mulligan |
American journal of respiratory cell and molecular biology | 2005 |
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Gene expression profiles reveal increased mClca3 (Gob5) expression and mucin production in a murine model of asbestos-induced fibrogenesis.
Sabo-Attwood T, Ramos-Nino M, Bond J, Butnor KJ, Heintz N, Gruber AD, Steele C, Taatjes DJ, Vacek P, Mossman BT |
The American Journal of Pathology | 2005 |
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Liver fibrosis
Bataller R, Brenner DA |
Journal of Clinical Investigation | 2005 |
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Pulmonary fibrosis: thinking outside of the lung.
Garantziotis S, Steele MP, Schwartz DA |
Journal of Clinical Investigation | 2004 |
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