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Citations to this article

The application of biofilm science to the study and control of chronic bacterial infections
William Costerton, … , Christopher Post, Garth Ehrlich
William Costerton, … , Christopher Post, Garth Ehrlich
Published November 15, 2003
Citation Information: J Clin Invest. 2003;112(10):1466-1477. https://doi.org/10.1172/JCI20365.
View: Text | PDF | Corrigendum
Perspective Series Article has an altmetric score of 17

The application of biofilm science to the study and control of chronic bacterial infections

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Abstract

Unequivocal direct observations have established that the bacteria that cause device-related and other chronic infections grow in matrix-enclosed biofilms. The diagnostic and therapeutic strategies that have served us so well in the partial eradication of acute epidemic bacterial diseases have not yielded accurate data or favorable outcomes when applied to these biofilm diseases. We discuss the potential benefits of the application of the new methods and concepts developed by biofilm science and engineering to the clinical management of infectious diseases.

Authors

William Costerton, Richard Veeh, Mark Shirtliff, Mark Pasmore, Christopher Post, Garth Ehrlich

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Total citations by year

Year: 2025 2024 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 2006 2005 2004 2003 1997 Total
Citations: 5 7 6 13 19 37 28 36 29 28 34 36 39 28 29 31 29 28 23 27 25 11 1 1 550
Citation information
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Citations to this article in year 2006 (27)

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Characterization, Distribution, and Expression of Novel Genes among Eight Clinical Isolates of Streptococcuspneumoniae
K Shen, J Gladitz, P Antalis, B Dice, B Janto, R Keefe, J Hayes, A Ahmed, R Dopico, N Ehrlich, J Jocz, L Kropp, S Yu, L Nistico, DP Greenberg, K Barbadora, RA Preston, JC Post, GD Ehrlich, FZ Hu
Infection and immunity 2006
The preterm parturition syndrome
R Romero, J Espinoza, JP Kusanovic, F Gotsch, S Hassan, O Erez, T Chaiworapongsa, M Mazor
BJOG: An International Journal of Obstetrics and Gynaecology 2006
The quorum-sensing molecule N-3-oxododecanoyl homoserine lactone (3OC12-HSL) enhances the host defence by activating human polymorphonuclear neutrophils (PMN)
C Wagner, S Zimmermann, G Brenner-Weiss, F Hug, B Prior, U Obst, GM Hänsch
Analytical and Bioanalytical Chemistry 2006
Direct detection of bacterial biofilms on the middle-ear mucosa of children with chronic otitis media
L Hall-Stoodley, FZ Hu, A Gieseke, L Nistico, D Nguyen, J Hayes, M Forbes, DP Greenberg, B Dice, A Burrows, PA Wackym, P Stoodley, JC Post, GD Ehrlich, JE Kerschner
JAMA : the journal of the American Medical Association 2006
Treatment and outcome of CPD-associated peritonitis
L Troidle, F Finkelstein
Annals of clinical microbiology and antimicrobials 2006
Phenotypic characterization of Streptococcus pneumoniae biofilm development
M Allegrucci, FZ Hu, K Shen, J Hayes, GD Ehrlich, JC Post, K Sauer
Journal of bacteriology 2006
Effect of oral decontamination with chlorhexidine on the incidence of nosocomial pneumonia: a meta-analysis
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Critical Care 2006
The endo-perio lesion: a critical appraisal of the disease condition
I Rotstein, JH Simon
Endodontic Topics 2006
Biofilm: Its Relevance In Kidney Disease
G Tapia, J Yee
Advances in Chronic Kidney Disease 2006
Die implantatassoziierte posttraumatische Osteitis: Bakterielle Biofilme und Infektabwehr als Protagonisten der lokalen Entzündungsreaktion
C Wagner, GM Hänsch, A Wentzensen, V Heppert
Der Unfallchirurg 2006
On the causes of persistent apical periodontitis: a review
PN Nair
International Endodontic Journal 2006
Bactericidal effect of Nd:YAG laser irradiation on some endodontic pathogens ex vivo
L Bergmans, P Moisiadis, W Teughels, BV Meerbeek, M Quirynen, P Lambrechts
International Endodontic Journal 2006
Bacterial Biofilms on the Sinus Mucosa of Human Subjects With Chronic Rhinosinusitis:
AR Sanderson, JG Leid, D Hunsaker
The Laryngoscope 2006
Mécanismes physiopathologiques des infections sur matériel orthopédique
L Bernard
Revue du Rhumatisme 2006
The Effect of Exposure to Irrigant Solutions on Apical Dentin Biofilms In Vitro
MS Clegg, FJ Vertucci, C Walker, M Belanger, LR Britto
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Co-selection of antibiotic and metal resistance
C Baker-Austin, MS Wright, R Stepanauskas, JV McArthur
Trends in Microbiology 2006
Microbial Biofilms: A Potential Source for Alloplastic Device Failure
LG Mercuri
Journal of Oral and Maxillofacial Surgery 2006
Preconceptional antibiotic treatment to prevent preterm birth in women with a previous preterm delivery
J Espinoza, O Erez, R Romero
American Journal of Obstetrics and Gynecology 2006
Evidence-Based Practice in the Management of Vascular Access Devices for Home Parenteral Nutrition Therapy
M Ryder
JPEN. Journal of parenteral and enteral nutrition 2006
Efficacy of N-Acetyl-Cysteine in Combination with Thiamphenicol in Sequential (Intramuscular/Aerosol) Therapy of Upper Respiratory Tract Infections Even When Sustained by Bacterial Biofilms
A Macchi, F Ardito, A Marchese, GC Schito, G Fadda
Journal of chemotherapy (Florence, Italy) 2006
Biofilm Formation by Staphylococcus Aureus and Pseudomonas Aeruginosa is Associated with an Unfavorable Evolution after Surgery for Chronic Sinusitis and Nasal Polyposis
Z Bendouah, J Barbeau, WA Hamad, M Desrosiers
Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery 2006
Endoscopically Guided Aerobic Cultures in Postsurgical Patients with Chronic Rhinosinusitis
CS Coffey, RE Sonnenburg, CT Melroy, MG Dubin, BA Senior
American journal of rhinology 2006
Use of an in Vitro Assay for Determination of Biofilm-Forming Capacity of Bacteria in Chronic Rhinosinusitis
Z Bendouah, J Barbeau, WA Hamad, M Desrosiers
American journal of rhinology 2006
Transcriptome and Phenotypic Responses of Vibrio cholerae to Increased Cyclic di-GMP Level
S Beyhan, AD Tischler, A Camilli, FH Yildiz
Journal of bacteriology 2006
Induction of Neutrophil Chemotaxis by the Quorum-Sensing Molecule N -(3-Oxododecanoyl)- l -Homoserine Lactone
S Zimmermann, C Wagner, W Müller, G Brenner-Weiss, F Hug, B Prior, U Obst, GM Hänsch
Infection and immunity 2006
Mycobacterium avium Genes Associated with the Ability To Form a Biofilm
Y Yamazaki, L Danelishvili, M Wu, M MacNab, LE Bermudez
Applied and environmental microbiology 2006
Plasmadeponierte Kohlenstoffbeschichtung auf urologischen Verweilkathetern: Vermeidung der Ausbildung von Inkrustationen und konsekutiven Komplikationen
N Laube, J Bradenahl, A Meißner, J v. Rappard, L Kleinen, SC Müller
Der Urologe, Ausgabe A 2006

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