Unequivocal direct observations have established that the bacteria that cause device-related and other chronic infections grow in matrix-enclosed biofilms. The diagnostic and therapeutic strategies that have served us so well in the partial eradication of acute epidemic bacterial diseases have not yielded accurate data or favorable outcomes when applied to these biofilm diseases. We discuss the potential benefits of the application of the new methods and concepts developed by biofilm science and engineering to the clinical management of infectious diseases.
William Costerton, Richard Veeh, Mark Shirtliff, Mark Pasmore, Christopher Post, Garth Ehrlich
Title and authors | Publication | Year |
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Characterization, Distribution, and Expression of Novel Genes among Eight Clinical Isolates of Streptococcuspneumoniae
K Shen, J Gladitz, P Antalis, B Dice, B Janto, R Keefe, J Hayes, A Ahmed, R Dopico, N Ehrlich, J Jocz, L Kropp, S Yu, L Nistico, DP Greenberg, K Barbadora, RA Preston, JC Post, GD Ehrlich, FZ Hu |
Infection and immunity | 2006 |
The preterm parturition syndrome
R Romero, J Espinoza, JP Kusanovic, F Gotsch, S Hassan, O Erez, T Chaiworapongsa, M Mazor |
BJOG: An International Journal of Obstetrics and Gynaecology | 2006 |
The quorum-sensing molecule N-3-oxododecanoyl homoserine lactone (3OC12-HSL) enhances the host defence by activating human polymorphonuclear neutrophils (PMN)
C Wagner, S Zimmermann, G Brenner-Weiss, F Hug, B Prior, U Obst, GM Hänsch |
Analytical and Bioanalytical Chemistry | 2006 |
Direct detection of bacterial biofilms on the middle-ear mucosa of children with chronic otitis media
L Hall-Stoodley, FZ Hu, A Gieseke, L Nistico, D Nguyen, J Hayes, M Forbes, DP Greenberg, B Dice, A Burrows, PA Wackym, P Stoodley, JC Post, GD Ehrlich, JE Kerschner |
JAMA : the journal of the American Medical Association | 2006 |
Treatment and outcome of CPD-associated peritonitis
L Troidle, F Finkelstein |
Annals of clinical microbiology and antimicrobials | 2006 |
Phenotypic characterization of Streptococcus pneumoniae biofilm development
M Allegrucci, FZ Hu, K Shen, J Hayes, GD Ehrlich, JC Post, K Sauer |
Journal of bacteriology | 2006 |
Effect of oral decontamination with chlorhexidine on the incidence of nosocomial pneumonia: a meta-analysis
LA Pineda, RG Saliba, AA el Solh |
Critical Care | 2006 |
The endo-perio lesion: a critical appraisal of the disease condition
I Rotstein, JH Simon |
Endodontic Topics | 2006 |
Biofilm: Its Relevance In Kidney Disease
G Tapia, J Yee |
Advances in Chronic Kidney Disease | 2006 |
Die implantatassoziierte posttraumatische Osteitis: Bakterielle Biofilme und Infektabwehr als Protagonisten der lokalen Entzündungsreaktion
C Wagner, GM Hänsch, A Wentzensen, V Heppert |
Der Unfallchirurg | 2006 |
On the causes of persistent apical periodontitis: a review
PN Nair |
International Endodontic Journal | 2006 |
Bactericidal effect of Nd:YAG laser irradiation on some endodontic pathogens ex vivo
L Bergmans, P Moisiadis, W Teughels, BV Meerbeek, M Quirynen, P Lambrechts |
International Endodontic Journal | 2006 |
Bacterial Biofilms on the Sinus Mucosa of Human Subjects With Chronic Rhinosinusitis:
AR Sanderson, JG Leid, D Hunsaker |
The Laryngoscope | 2006 |
Mécanismes physiopathologiques des infections sur matériel orthopédique
L Bernard |
Revue du Rhumatisme | 2006 |
The Effect of Exposure to Irrigant Solutions on Apical Dentin Biofilms In Vitro
MS Clegg, FJ Vertucci, C Walker, M Belanger, LR Britto |
Journal of Endodontics | 2006 |
Co-selection of antibiotic and metal resistance
C Baker-Austin, MS Wright, R Stepanauskas, JV McArthur |
Trends in Microbiology | 2006 |
Microbial Biofilms: A Potential Source for Alloplastic Device Failure
LG Mercuri |
Journal of Oral and Maxillofacial Surgery | 2006 |
Preconceptional antibiotic treatment to prevent preterm birth in women with a previous preterm delivery
J Espinoza, O Erez, R Romero |
American Journal of Obstetrics and Gynecology | 2006 |
Evidence-Based Practice in the Management of Vascular Access Devices for Home Parenteral Nutrition Therapy
M Ryder |
JPEN. Journal of parenteral and enteral nutrition | 2006 |
Efficacy of N-Acetyl-Cysteine in Combination with Thiamphenicol in Sequential (Intramuscular/Aerosol) Therapy of Upper Respiratory Tract Infections Even When Sustained by Bacterial Biofilms
A Macchi, F Ardito, A Marchese, GC Schito, G Fadda |
Journal of chemotherapy (Florence, Italy) | 2006 |
Biofilm Formation by Staphylococcus Aureus and Pseudomonas Aeruginosa is Associated with an Unfavorable Evolution after Surgery for Chronic Sinusitis and Nasal Polyposis
Z Bendouah, J Barbeau, WA Hamad, M Desrosiers |
Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery | 2006 |
Endoscopically Guided Aerobic Cultures in Postsurgical Patients with Chronic Rhinosinusitis
CS Coffey, RE Sonnenburg, CT Melroy, MG Dubin, BA Senior |
American journal of rhinology | 2006 |
Use of an in Vitro Assay for Determination of Biofilm-Forming Capacity of Bacteria in Chronic Rhinosinusitis
Z Bendouah, J Barbeau, WA Hamad, M Desrosiers |
American journal of rhinology | 2006 |
Transcriptome and Phenotypic Responses of Vibrio cholerae to Increased Cyclic di-GMP Level
S Beyhan, AD Tischler, A Camilli, FH Yildiz |
Journal of bacteriology | 2006 |
Induction of Neutrophil Chemotaxis by the Quorum-Sensing Molecule N -(3-Oxododecanoyl)- l -Homoserine Lactone
S Zimmermann, C Wagner, W Müller, G Brenner-Weiss, F Hug, B Prior, U Obst, GM Hänsch |
Infection and immunity | 2006 |
Mycobacterium avium Genes Associated with the Ability To Form a Biofilm
Y Yamazaki, L Danelishvili, M Wu, M MacNab, LE Bermudez |
Applied and environmental microbiology | 2006 |
Plasmadeponierte Kohlenstoffbeschichtung auf urologischen Verweilkathetern: Vermeidung der Ausbildung von Inkrustationen und konsekutiven Komplikationen
N Laube, J Bradenahl, A Meißner, J v. Rappard, L Kleinen, SC Müller |
Der Urologe, Ausgabe A | 2006 |