JCI - Citations to Immunologic responses to bacteriophage ϕX 174 in immunodeficiency diseases

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Immunologic responses to bacteriophage ϕX 174 in immunodeficiency diseases

Hans D. Ochs, … , Starkey D. Davis, Ralph J. Wedgwood

Hans D. Ochs, … , Starkey D. Davis, Ralph J. Wedgwood

Published December 1, 1971
Citation Information: J Clin Invest. 1971;50(12):2559-2568. https://doi.org/10.1172/JCI106756.

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Citations to this article (170)

Title and authors	Publication	Year
Oral bacteriophages and their potential as adjunctive treatments for periodontitis: a narrative review Kabwe M, Tucci J, Darby I, Dashper S	Journal of Oral Microbiology	2025
The Next Generation of Drug Delivery: Harnessing the Power of Bacteriophages. Aljabali AAA, Aljbaly MBM, Obeid MA, Shahcheraghi SH, Tambuwala MM	Methods in molecular biology (Clifton, N.J.)	2024
The untapped potential of phage model systems as therapeutic agents Romeyer Dherbey J, Bertels F	Virus Evolution	2024
Mini review advantages and limitations of lytic phages compared with chemical antibiotics to combat bacterial infections. Guo Z, Yuan M, Chai J	Heliyon	2024
Phage therapy could be key to conquering persistent bacterial lung infections in children Sithu Shein AM, Hongsing P, Khatib A, Phattharapornjaroen P, Miyanaga K, Cui L, Shibuya K, Amarasiri M, Monk PN, Kicic A, Chatsuwan T, Higgins PG, Abe S, Wannigama DL	npj Antimicrobials and Resistance	2024
Development of Host Immune Response to Bacteriophage in a Lung Transplant Recipient on Adjunctive Phage Therapy for a Multidrug-Resistant Pneumonia. Dan JM, Lehman SM, Al-Kolla R, Penziner S, Afshar K, Yung G, Golts E, Law N, Logan C, Kovach Z, Mearns G, Schooley RT, Aslam S, Crotty S	The Journal of Infectious Diseases	2023
Human Neutrophil Response to Pseudomonas Bacteriophage PAK_P1, a Therapeutic Candidate. Roach DR, Noël B, Chollet-Martin S, de Jode M, Granger V, Debarbieux L, de Chaisemartin L	Viruses	2023
CD5 B-Cell Predominant Primary Immunodeficiency: Part of the Spectrum of MAGT1 Deficiency. Rowane MJ, Stewart-Bates BC, Doll RJ, Meyerson HJ, Venglarcik JS 3rd, Callahan M, Fill L, Saab R, Ochs HD, Hostoffer RW Jr		2023
Evaluation of the impact of repeated intravenous phage doses on mammalian host-phage interactions. Tan X, Chen K, Jiang Z, Liu Z, Wang S, Ying Y, Zhang J, Yuan S, Huang Z, Gao R, Zhao M, Weng A, Yang Y, Luo H, Zhang D, Ma Y	Journal of virology	2023
Effects of Klebsiella pneumoniae Bacteriophages on IRAK3 Knockdown/Knockout THP-1 Monocyte Cell Lines. Schubert BD, Ku H, Kabwe M, Nguyen TH, Irving H, Tucci J	Viruses	2022
Tracking the phage trends: A comprehensive review of applications in therapy and food production. Jaglan AB, Anand T, Verma R, Vashisth M, Virmani N, Bera BC, Vaid RK, Tripathi BN	Frontiers in microbiology	2022
Advances in Phage Therapy: Targeting the Burkholderia cepacia Complex P Lauman, JJ Dennis	Viruses	2021
Phage-specific antibodies K Gembara, K Dąbrowska	Current Opinion in Biotechnology	2021
Bacteriophages and the Immune System M Popescu, JD Belleghem, A Khosravi, PL Bollyky	Annual Review of Virology	2021
Pf Bacteriophage and Their Impact on Pseudomonas Virulence, Mammalian Immunity, and Chronic Infections PR Secor, EB Burgener, M Kinnersley, LK Jennings, V Roman-Cruz, M Popescu, JD Belleghem, N Haddock, C Copeland, LA Michaels, CR de Vries, Q Chen, J Pourtois, TJ Wheeler, CE Milla, PL Bollyky	Frontiers in immunology	2020
The Rationale for Using Bacteriophage to Treat and Prevent Periprosthetic Joint Infections JD Belleghem, R Manasherob, R Miȩdzybrodzki, P Rogóż, A Górski, GA Suh, PL Bollyky, DF Amanatullah	Frontiers in microbiology	2020
Natural and Induced Antibodies Against Phages in Humans: Induction Kinetics and Immunogenicity for Structural Proteins of PB1-Related Phages K Hodyra-Stefaniak, Z Kaźmierczak, J Majewska, S Sillankorva, P Miernikiewicz, R Międzybrodzki, A Górski, J Azeredo, R Lavigne, D Lecion, S Nowak, M Harhala, P Waśko, B Owczarek, K Gembara, K Dąbrowska		2020
Anti-phage serum antibody responses and the outcome of phage therapy M Łusiak-Szelachowska, R Międzybrodzki, W Fortuna, J Borysowski, A Górski	Folia Microbiologica	2020
Defining Common Variable Immunodeficiency Disorders in 2020 R Ameratunga, C Allan, ST Woon	Immunology and Allergy Clinics of North America	2020
Class switch recombination defects: impact on b cell maturation and antibody responses ED Renner, CE Krätz, JS Orange, B Hagl, S Rylaarsdam, G Notheis, A Durandy, TR Torgerson, HD Ochs	Clinical Immunology	2020
Perspective: Evolving Concepts in the Diagnosis and Understanding of Common Variable Immunodeficiency Disorders (CVID) R Ameratunga, ST Woon	Clinical Reviews in Allergy & Immunology	2019
Pulmonary Manifestations of Predominantly Antibody Deficiencies Saghazadeh A, Rezaei N		2019
Phage therapy: What factors shape phage pharmacokinetics and bioavailability? Systematic and critical review K Dąbrowska	Medicinal Research Reviews	2019
Pulmonary Manifestations of Primary Immunodeficiency Diseases SA Mahdaviani, N Rezaei		2019
Efficacy and potential of phage therapy against multidrug resistant Shigella spp SS Tang, SK Biswas, WS Tan, AK Saha, BF Leo	PeerJ	2019
Bacteriophages engineered to display foreign peptides may become short‐circulating phages K HodyraStefaniak, K Lahutta, J Majewska, Z Kaźmierczak, D Lecion, M Harhala, W Kęska, B Owczarek, E JończykMatysiak, A Kłopot, P Miernikiewicz, D Kula, A Górski, K Dąbrowska	Microbial Biotechnology	2019
Bacteriophages as Alternatives to Antibiotics in Clinical Care D Romero-Calle, RG Benevides, A Góes-Neto, C Billington	Antibiotics	2019
Pharmacologically Aware Phage Therapy: Pharmacodynamic and Pharmacokinetic Obstacles to Phage Antibacterial Action in Animal and Human Bodies K Dąbrowska, ST Abedon	Microbiology and molecular biology reviews : MMBR	2019
Antibacterial Drug Discovery to Combat MDR: Natural Compounds, Nanotechnology and Novel Synthetic Sources I Ahmad, S Ahmad, KP Rumbaugh		2019
Antibody deficiency testing for primary immunodeficiency RA Marsh, JS Orange	Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology	2019
Phage Therapy: A Practical Approach A Górski, R Międzybrodzki, J Borysowski		2019
Rapid immune reconstitution of SCID-X1 canines after G-CSF/AMD3100 mobilization and in vivo gene therapy O Humbert, F Chan, YS Rajawat, TR Torgerson, CR Burtner, NW Hubbard, D Humphrys, ZK Norgaard, P ODonnell, JE Adair, GD Trobridge, AM Scharenberg, PJ Felsburg, DJ Rawlings, HP Kiem	Blood Advances	2018
Applications for Bacteriophage Therapy during Pregnancy and the Perinatal Period LL Furfaro, BJ Chang, MS Payne	Frontiers in microbiology	2018
Close Encounters of Three Kinds: Bacteriophages, Commensal Bacteria, and Host Immunity EC Keen, G Dantas	Trends in Microbiology	2018
Contribution of the Immune Response to Phage Therapy O Krut, I Bekeredjian-Ding	Journal of immunology (Baltimore, Md. : 1950)	2018
Interactions between Bacteriophage, Bacteria, and the Mammalian Immune System JV Belleghem, K Dąbrowska, M Vaneechoutte, J Barr, P Bollyky	Viruses	2018
A Systematic and Critical Review of Bacteriophage Therapy Against Multidrug-resistant ESKAPE Organisms in Humans LE Haddad, CP Harb, MA Gebara, MA Stibich, RF Chemaly	Clinical Infectious Diseases	2018
Dynamic changes of the normal B lymphocyte repertoire in CLL in response to ibrutinib or FCR chemo-immunotherapy S Schliffke, M Sivina, E Kim, L Wenserski, B Thiele, N Akyüz, C Falker-Gieske, D Statovci, A Oberle, T Thenhausen, A Krohn-Grimberghe, C Bokemeyer, N Jain, Z Estrov, A Ferrajoli, W Wierda, M Keating, JA Burger, M Binder	OncoImmunology	2017
Current review-The rise of bacteriophage as a unique therapeutic platform in treating peri-prosthetic joint infections: PHAGE THERAPY FOR PROSTHETIC JOINT INFECTION ZZ Akanda, M Taha, H Abdelbary	Journal of orthopaedic research : official publication of the Orthopaedic Research Society	2017
Phage Therapy in the Era of Synthetic Biology EM Barbu, KC Cady, B Hubby	Cold Spring Harbor perspectives in biology	2016
PhiXing-it, displaying foreign peptides on bacteriophage ΦX174 KJ Christakos, JA Chapman, BA Fane, SK Campos	Virology	2016
SpringerBriefs in Biochemistry and Molecular Biology J Nicastro, S Wong, RA Slavcev	SpringerBriefs in Biochemistry and Molecular Biology	2016
Bacteriophage Therapy: Advances in Formulation Strategies and Human Clinical Trials D Vandenheuvel, R Lavigne, H Brüssow	Annual Review of Virology	2015
Safety and efficacy of phage therapy via the intravenous route P Speck, A Smithyman, A Millard	FEMS Microbiology Letters	2015
Comparison of Diagnostic Criteria for Common Variable Immunodeficiency Disorder R Ameratunga, M Brewerton, C Slade, A Jordan, D Gillis, R Steele, W Koopmans, ST Woon	Frontiers in immunology	2014
Laboratory Diagnosis of Primary Immunodeficiencies BA Locke, T Dasu, JW Verbsky	Clinical Reviews in Allergy & Immunology	2014
The T-cell-dependent antibody response assay in nonclinical studies of pharmaceuticals and chemicals: Study design, data analysis, interpretation H Lebrec, B Molinier, D Boverhof, M Collinge, W Freebern, K Henson, DT Mytych, HD Ochs, R Wange, Y Yang, L Zhou, J Arrington, MS Christin-Piché, J Shenton	Regulatory Toxicology and Pharmacology	2014
Diagnostic Immunization with Bacteriophage Î¦X 174 in Patients with Common Variable Immunodeficiency/Hypogammaglobulinemia LL Smith, R Buckley, P Lugar	Frontiers in immunology	2014
Isolation of a Bacteriophage and Its Depolymerase Specific for K1 Capsule of Klebsiella pneumoniae: Implication in Typing and Treatment TL Lin, PF Hsieh, YT Huang, WC Lee, YT Tsai, PA Su, YJ Pan, CR Hsu, MC Wu, JT Wang	The Journal of Infectious Diseases	2014
Adventitious agents in viral vaccines: Lessons learned from 4 case studies J Petricciani, R Sheets, E Griffiths, I Knezevic	Biologicals	2014
Primary Immunodeficiency Disorders M Berger, ER Stiehm		2014
New diagnostic criteria for Common Variable Immune Deficiency (CVID), which may assist with decisions to treat with intravenous or subcutaneous Immunoglobulin R Ameratunga, ST Woon, D Gillis, W Koopmans, R Steele	Clinical & Experimental Immunology	2013
B-cell reconstitution for SCID: Should a conditioning regimen be used in SCID treatment? E Haddad, S Leroy, RH Buckley	Journal of Allergy and Clinical Immunology	2013
Use of vaccines in the evaluation of presumed immunodeficiency M Ballow	Annals of Allergy, Asthma & Immunology	2013
Use of bacteriophages in the treatment of Pseudomonas aeruginosa infections J Soothill	Expert Review of Anti-infective Therapy	2013
Therapeutic Potential of Staphylococcal Bacteriophages for Nasal Decolonization of <i>Staphylococcus aureus</i> in Mice MH Narasimhaiah, JY Asrani, SM Palaniswamy, J Bhat, SE George, R Srinivasan, A Vipra, SN Desai, RP Junjappa, P Roy, B Sriram, S Padmanabhan	Advances in Microbiology	2013
Post-Transplantation B Cell Function in Different Molecular Types of SCID RH Buckley, CM Win, BK Moser, RE Parrott, E Sajaroff, M Sarzotti-Kelsoe	Journal of Clinical Immunology	2012
Use and interpretation of diagnostic vaccination in primary immunodeficiency: A working group report of the Basic and Clinical Immunology Interest Section of the American Academy of Allergy, Asthma & Immunology JS Orange, M Ballow, ER Stiehm, ZK Ballas, J Chinen, MD la Morena, D Kumararatne, TO Harville, P Hesterberg, M Koleilat, S McGhee, EE Perez, J Raasch, R Scherzer, H Schroeder, C Seroogy, A Huissoon, RU Sorensen, R Katial	Journal of Allergy and Clinical Immunology	2012
Immunocompatibility of Bacteriophages as Nanomedicines T Kaur, N Nafissi, O Wasfi, K Sheldon, S Wettig, R Slavcev	Journal of Nanotechnology	2012
Propionibacterium acnes Bacteriophages Display Limited Genetic Diversity and Broad Killing Activity against Bacterial Skin Isolates LJ Marinelli, S Fitz-Gibbon, C Hayes, C Bowman, M Inkeles, A Loncaric, DA Russell, D Jacobs-Sera, S Cokus, M Pellegrini, J Kim, JF Miller, GF Hatfull, RL Modlin, JE Davies	mBio	2012
Impact of rituximab on human in vivo antibody immune responses Mark Pescovitz, Troy Torgerson, Hans Ochs, Elizabeth Ocheltree, Paula McGee, Heidi Krause-Steinrauf, John Lachin, Jennifer Canniff, Carla Greenbaum, Kevan Herold, Jay Skyler, Adriana Weinberg		2011
Antibody forming cells and plasmablasts in peripheral blood in CVID patients after vaccination Z Chovancova, M Vlkova, J Litzman, J Lokaj, V Thon	Vaccine	2011
Advances in Immunology E Pinaud, M Marquet, R Fiancette, S Péron, C Vincent-Fabert, Y Denizot, M Cogné	Advances in Immunology Volume 110	2011
Heterozygous signal transducer and activator of transcription 3 mutations in hyper-IgE syndrome result in altered B-cell maturation A Meyer-Bahlburg, ED Renner, S Rylaarsdam, J Reichenbach, LF Schimke, A Marks, H Tcheurekdjian, R Hostoffer, A Brahmandam, TR Torgerson, BH Belohradsky, DJ Rawlings, HD Ochs	Journal of Allergy and Clinical Immunology	2011
Oligoclonality, impaired class switch and B-cell memory responses in WHIM syndrome PJ Guire, C Cunningham-Rundles, H Ochs, GA Diaz	Clinical Immunology	2010
Vaccination against tick-borne encephalitis virus tests specific IgG production ability in patients under immunoglobulin substitution therapy MG Seidel, E Grohmann, K Sadeghi, A Pollak, A Heitger, E Förster-Waldl	Vaccine	2010
Bacteriophage therapy for Staphylococcus aureus bacteremia in streptozotocin-induced diabetic mice R Sunagar, SA Patil, RK Chandrakanth	Research in Microbiology	2010
A Short Burst of Oral Corticosteroid for Children with Acute Asthma: Is There an Impact on Immunity? FM Ducharme, HD Ochs, S Resendes, X Zhang, BD Mazer	Pediatric Allergy, Immunology, and Pulmonology	2010
The Use of Immunoglobulin Therapy for Patients With Primary Immune Deficiency: An Evidence-Based Practice Guideline N Shehata, V Palda, T Bowen, E Haddad, TB Issekutz, B Mazer, R Schellenberg, R Warrington, D Easton, D Anderson, H Hume	Transfusion Medicine Reviews	2010
Biological Gene Delivery Vehicles: Beyond Viral Vectors Y Seow, MJ Wood	Molecular Therapy	2009
Immunologic reconstitution during PEG-ADA therapy in an unusual mosaic ADA deficient patient P Liu, I Santisteban, LM Burroughs, HD Ochs, TR Torgerson, MS Hershfield, DJ Rawlings, AM Scharenberg	Clinical Immunology	2009
Comèl-Netherton syndrome defined as primary immunodeficiency ED Renner, D Hartl, S Rylaarsdam, ML Young, L Monaco-Shawver, G Kleiner, ML Markert, ER Stiehm, BH Belohradsky, MP Upton, TR Torgerson, JS Orange, HD Ochs	Journal of Allergy and Clinical Immunology	2009
Phage therapy JN Housby, NH Mann	Drug Discovery Today	2009
The role of costimulation in antibody deficiencies: ICOS and common variable immunodeficiency PF Yong, U Salzer, B Grimbacher	Immunological Reviews	2009
PERSISTENT ANTIBODY DEPLETION AFTER RITUXIMAB IN THREE CHILDREN WITH AUTOIMMUNE CYTOPENIAS MM Adeli, BH Eichner, C Thornburg, L Williams	Pediatric Hematology-Oncology	2009
Bacteriophage biocontrol in animals and meat products RJ Atterbury	Microbial Biotechnology	2009
Rituximab, B-lymphocyte depletion, and preservation of beta-cell function. Pescovitz MD, Greenbaum CJ, Krause-Steinrauf H, Becker DJ, Gitelman SE, Goland R, Gottlieb PA, Marks JB, McGee PF, Moran AM, Raskin P, Rodriguez H, Schatz DA, Wherrett D, Wilson DM, Lachin JM, Skyler JS	The New England journal of medicine	2009
Effect of Therapeutic Integrin (CD11a) Blockade with Efalizumab on Immune Responses to Model Antigens in Humans: Results of a Randomized, Single Blind Study JG Krueger, HD Ochs, P Patel, E Gilkerson, E Guttman-Yassky, W Dummer	Journal of Investigative Dermatology	2008
Proteasome inhibitors enhance bacteriophage lambda (lambda) mediated gene transfer in mammalian cells K Volcy, S Dewhurst	Virology	2008
Assessment of protein antibody response in patients with suspected immune deficiency AK Chouksey, M Berger	Annals of Allergy Asthma & Immunology	2008
Intensive postgrafting immune suppression combined with nonmyeloablative conditioning for transplantation of HLA-identical hematopoietic cell grafts: results of a pilot study for treatment of primary immunodeficiency disorders LM Burroughs, R Storb, WM Leisenring, MA Pulsipher, MR Loken, TR Torgerson, HD Ochs, AE Woolfrey	Bone Marrow Transplantation	2007
Viruses vs. Superbugs T Häusler		2006
Rituximab Inhibits the In Vivo Primary and Secondary Antibody Response to a Neoantigen, Bacteriophage phiX174 CM Bearden, A Agarwal, BK Book, CA Vieira, RA Sidner, HD Ochs, M Young, MD Pescovitz	American Journal of Transplantation	2005
A transgenic mouse model for studying the clearance of blood-borne pathogens via human complement receptor 1 (CR1) A Repik, SE Pincus, I Ghiran, A Nicholson-Weller, DR Asher, AM Cerny, LS Casey, SM Jones, SN Jones, N Mohamed, LB Klickstein, G Spitalny, RW Finberg	Clinical & Experimental Immunology	2005
Bacterial viruses against viruses pathogenic for man? R Miedzybrodzki, W Fortuna, B Weber-Dabrowska, A Gorski	Virus Research	2005
Functional and molecular evaluation of lymphocytes TA Fleisher, JB Oliveira	Journal of Allergy and Clinical Immunology	2004
Interleukin receptor–associated kinase (IRAK-4) deficiency associated with bacterial infections and failure to sustain antibody responses N Day, N Tangsinmankong, H Ochs, R Rucker, C Picard, JL Casanova, S Haraguchi, R Good	The Journal of Pediatrics	2004
Bacteriophages: Biology and Applications C Westwater, D Schofield	Bacteriophages: Biology and Applications	2004
Current concepts and review of alefacept in the treatment of psoriasis GG Krueger	Dermatologic Clinics	2004
Janus kinase 3 (JAK3) deficiency: clinical, immunologic, and molecular analyses of 10 patients and outcomes of stem cell transplantation JL Roberts, A Lengi, SM Brown, M Chen, YJ Zhou, JJ O'Shea, RH Buckley	Blood	2003
Inducible CO-stimulator molecule, a candidate gene for defective isotype switching, is normal in patients with hyper-IgM syndrome of unknown molecular diagnosis WI Lee, Q Zhu, E Gambine, YZ Jin, AA Welcher, HD Ochs	Journal of Allergy and Clinical Immunology	2003
New insights into the possible role of bacteriophages in host defense and disease A Gorski, K Dabrowska, K Switala-Jeleń, M Nowaczyk, B Weber-Dabrowska, J Boratynski, J Wietrzyk, A Opolski	Medical immunology (London, England)	2003
CD4+ T-cell–directed antibody responses are maintained in patients with psoriasis receiving alefacept: results of a randomized study AB Gottlieb, TB Casale, E Frankel, B Goffe, N Lowe, HD Ochs, JL Roberts, K Washenik, AK Vaishnaw, KB Gordon	Journal of the American Academy of Dermatology	2003
The prospect for bacteriophage therapy in Western medicine CR Merril, D Scholl, SL Adhya	Nature Reviews Drug Discovery	2003
Absence of Memory B Cells in Patients with Common Variable Immunodeficiency K Agematsu, T Futatani, S Hokibara, N Kobayashi, M Takamoto, S Tsukada, H Suzuki, S Koyasu, T Miyawaki, K Sugane, A Komiyama, HD Ochs	Clinical Immunology	2002
Selective targeting of T cell subsets: focus on alefacept – a remittive therapy for psoriasis GG Krueger	Expert Opinion on Biological Therapy	2002
The antibody response to bacteriophage is linked to the lymphopenia gene in congenic BioBreeding rats L Clark, C Greenbaum, J Jiang, Ã Lernmark, H Ochs	FEMS Immunology & Medical Microbiology	2002
Severe deficiency of switched memory B cells (CD27+IgM−IgD−) in subgroups of patients with common variable immunodeficiency: a new approach to classify a heterogeneous disease K Warnatz, A Denz, R Dräger, M Braun, C Groth, G Wolff-Vorbeck, H Eibel, M Schlesier, HH Peter	Blood	2002
Long-Term Low-Dose IL-2 Enhances Immune Function in Common Variable Immunodeficiency C Cunningham-Rundles, C Bodian, HD Ochs, S Martin, M Reiter-Wong, Z Zhuo	Clinical Immunology	2001
Defective surface expression of attractin on T cells in patients with common variable immunodeficiency (CVID) N Pozzi, L Gaetaniello, B Martire, DD Mattia, B Balestrieri, E Cosentini, SF Schlossman, JS Duke-Cohan, C Pignata	Clinical & Experimental Immunology	2001
Gene Therapy for Acute and Acquired Diseases P Factor		2001
Prokaryotic gene therapy to combat multidrug resistant bacterial infection JS Norris, C Westwater, D Schofield	Gene Therapy	2000
Analysis of engraftment, graft-versus-host disease, and immune recovery following unrelated donor cord blood transplantation BG Thomson, KA Robertson, D Gowan, D Heilman, HE Broxmeyer, D Emanuel, P Kotylo, Z Brahmi, FO Smith	Blood	2000
CTLA4Ig-mediated blockade of T-cell costimulation in patients with psoriasis vulgaris JR Abrams, MG Lebwohl, CA Guzzo, BV Jegasothy, MT Goldfarb, BS Goffe, A Menter, NJ Lowe, G Krueger, MJ Brown, RS Weiner, MJ Birkhofer, GL Warner, KK Berry, PS Linsley, JG Krueger, HD Ochs, SL Kelley, S Kang	Journal of Clinical Investigation	1999
Diminished expression of CD40 ligand may contribute to the defective humoral immunity in patients with MHC class II deficiency S Nonoyama, A Etzioni, H Toru, DP Ruggerie, D Lewis, S Pollack, A Aruffo, JI Yata, HD Ochs	European Journal of Immunology	1998
Mutations of the CD40 Ligand Gene and Its Effect on CD40 Ligand Expression in Patients With X-Linked Hyper IgM Syndrome K Seyama, S Nonoyama, I Gangsaas, D Hollenbaugh, HF Pabst, A Aruffo, HD Ochs	Blood	1998
Bacteriophage therapy and prophylaxis: rediscovery and renewed assessment of potential PA Barrow, JS Soothill	Trends in Microbiology	1997
Missense mutations affecting a conserved cysteine pair in the TH domain of Btk M Vihinen, BF Nore, PT Mattsson, CM Bäckesjö, M Nars, S Koutaniemi, C Watanabe, T Lester, A Jones, HD Ochs, CI Smith	FEBS Letters	1997
Normal Immunologic Response to a Neoantigen, Bacteriophage ΦX-174, in Baboons With Long-Term Lymphohematopoietic Reconstitution From Highly Purified CD34+ Lin− Allogeneic Marrow Cells RG Andrews, A Winkler, J Potter, E Bryant, GH Knitter, ID Bernstein, HD Ochs	Blood	1997
Full Immunologic Reconstitution Following Nonconditioned Bone Marrow Transplantation for Canine X-Linked Severe Combined Immunodeficiency PJ Felsburg, RL Somberg, BJ Hartnett, SF Suter, PS Henthorn, PF Moore, KI Weinberg, HD Ochs	Blood	1997
The Primary Immunodeficiencies FS Rosen, MD Cooper, RJ Wedgwood	New England Journal of Medicine	1995
Suppression of human immunoglobulin E antibody production by a new naphthalene derivative Y Uejima, K Takahashi, K Komoriya, S Kurozumi, HD Ochs	Immunopharmacology	1995
A new RFLP marker, SP282, at thebtk locus for genetic analysis in X-linked agammaglobulinaemia families SP Kwan, AP Walker, T Hagemann, S Gupta, B Vayuvegula, HD Ochs	Prenatal Diagnosis	1994
Deletion within the Src homology domain 3 of Bruton's tyrosine kinase resulting in X-linked agammaglobulinemia (XLA) Q Zhu, M Zhang, DJ Rawlings, M Vihinen, T Hagemann, DC Saffran, SP Kwan, L Nilsson, CI Smith, ON Witte, SH Chen, HD Ochs	Journal of Experimental Medicine	1994
CD40 ligand expression is defective in a subset of patients with common variable immunodeficiency M Farrington, LS Grosmaire, S Nonoyama, SH Fischer, D Hollenbaugh, JA Ledbetter, RJ Noelle, A Aruffo, HD Ochs	Proceedings of the National Academy of Sciences	1994
The role of CD40L (gp39)/CD40 in T/B cell interaction and primary immunodeficiency HD Ochs, D Hollenbaugh, A Aruffo	Research in Immunology	1994
Laboratory Aspects of Immunology SE Pacheco, WT Shearer	Pediatric Clinics of North America	1994
The molecular basis for T cell help in humoral immunity: CD40 and its ligand, gp39 LS Marshall, A Aruffo, JA Ledbetter, RJ Noelle	Journal of Clinical Immunology	1993
Evaluation of families wherein a single male manifests a phenotype of X-linked lymphoproliferative disease (XLP) HL Grierson, J Skare, J Church, T Silberman, JR Davis, N Kobrinsky, R McGregor, S Israels, J McCarty, LG Andrews, T Blecha, S Erdman, A Obringer, D Scharnhorst, DT Purtilo	American Journal of Medical Genetics	1993
The CD40 ligand, gp39, is defective in activated T cells from patients with X-linked hyper-IgM syndrome A Aruffo, M Farrington, D Hollenbaugh, X Li, A Milatovich, S Nonoyama, J Bajorath, LS Grosmaire, R Stenkamp, M Neubauer, RL Roberts, RJ Noelle, JA Ledbetter, U Francke, HD Ochs	Cell	1993
B cell activation via CD40 is required for specific antibody production by antigen-stimulated human B cells S Nonoyama, D Hollenbaugh, A Aruffo, JA Ledbetter, HD Ochs	Journal of Experimental Medicine	1993
Antibody responses to protein, polysaccharide, and ΦX174 antigens in the hyperimmunoglobulinemia E (hyper-IgE) syndrome KA Sheerin, RH Buckley	Journal of Allergy and Clinical Immunology	1991
Lymphocyte alterations in zinc-deficient calves with lethal trait A46 LE Perryman, DR Leach, WC Davis, WD Mickelsen, SR Heller, HD Ochs, JA Ellis, E Brummerstedt	Veterinary Immunology and Immunopathology	1989
Abnormal primary antibody responses in pediatric trauma patients NW Wilson, HD Ochs, B Peterson, RN Hamburger, JF Bastian	The Journal of Pediatrics	1989
Human antibody responses to bacteriophage φX 174: Sequential induction of IgM and IgG subclass antibody KH Pyun, HD Ochs, RJ Wedgwood, Y Xiqiang, SR Heller, CB Reimer	Clinical Immunology and Immunopathology	1989
Advances in Virus Research LA Babiuk, MJ Lawman, HB Ohmann	Advances in virus research	1988
Bone Marrow Findings in Immunodeficiency Syndromes MJ Duggan, DD Weisenburger, NC Sun, DT Purtilo	Hematology/Oncology Clinics of North America	1988
Bone marrow transplantation in DiGeorge syndrome AB Goldsobel, A Haas, ER Stiehm	The Journal of Pediatrics	1987
Differentiation of B Lymphocytes CJ Paige, RH Gisler		1987
Antibody producing capacity to the bacteriophage phi X174 in rheumatoid arthritis. Bucknall R, Bacon P, Elson C, Jones JV	Annals of the rheumatic diseases	1987
In vivo chromosomal instability in ataxia-telangiectasia homozygotes and heterozygotes MP Rosin, HD Ochs	Human Genetics	1986
iC3b Receptor and antibody formation RJ Wedgwood	Molecular Immunology	1986
Immunologic Disorders: The Regulation of Humoral Immunity RJ Wedgwood, HD Ochs	Vox Sanguinis	1986
Variability in B cell maturation and differentiation in X-linked agammaglobulinemia FE Leickley, R Buckley	Clinical & Experimental Immunology	1986
Human immune responses in vivo to protein (KLH) and polysaccharide (DNP-Ficoll) neoantigens: normal subjects compared with bone marrow transplant patients on cyclosporine PL Amlot, AE Hayes, D Gray, EC Gordon-Smith, JH Humphrey	Clinical & Experimental Immunology	1986
Complement, membrane glycoproteins, and complement receptors: Their role in regulation of the immune response HD Ochs, RJ Wedgwood, SR Heller, PG Beatty	Clinical Immunology and Immunopathology	1986
Transient immune deficiency in patients with acute Epstein-Barr virus infection AK Junker, HD Ochs, EA Clark, ML Puterman, RJ Wedgwood	Clinical Immunology and Immunopathology	1986
Graft-versus-Host Reactions and Disease GW Santos, AD Hess, GB Vogelsan	Immunological Reviews	1985
Graft-versus-Host-Reactions: The History that never Was, and the Way Things Happened to Happen M Simonsen	Immunological Reviews	1985
Antibody to bacteriophage phi X 174 synthesized by cultured human peripheral blood lymphocytes J Bohnsack, HD Ochs, RJ Wedgwood, SR Heller	Clinical & Experimental Immunology	1985
Defective humoral immunity in pediatric acquired immune deficiency syndrome LJ Bernstein, HD Ochs, RJ Wedgwood, A Rubinstein	The Journal of Pediatrics	1985
Antibody deficiency with normal immunoglobulins in a child with hypoplastic anemia AP Knutsen, DM O'Connor	Clinical Immunology and Immunopathology	1985
Epstein-Barr virus-induced lymphoblastoid cell lines derived from the peripheral blood of patients with X-linked agammaglobulinemia can secrete IgM D Levitt, H Ochs, RJ Wedgwood	Journal of Clinical Immunology	1984
Characterization of Exogenous Type D Retrovirus from a Fibroma of a Macaque with Simian AIDS and Fibromatosis K Stromberg, RE Benveniste, LO Arthur, H Rabin, WE Giddens, HD Ochs, WR Morton, CC Tsai	Science	1984
The role of complement in the induction of antibody responses HD Ochs, RJ Wedgwood, MM Frank, SR Heller, SW Hosea	Clinical & Experimental Immunology	1983
Colonic nodular lymphoid hyperplasia in a child with antibody deficiency and near-normal immunoglobulins AP Knutsen, DF Merten, RH Buckley	The Journal of Pediatrics	1981
Differentiation of lymphocyte function in vivo following transplantation of thymic epithelial monolayers HG Herrod, WB Wheeler, AS Hanissian, HD Ochs, J Willis-Carr, CR Handorf	Clinical Immunology and Immunopathology	1981
Successful Treatment of ECHOvirus Meningoencephalitis and Myositis-Fasciitis with Intravenous Immune Globulin Therapy in a Patient with X-Linked Agammaglobulinemia PJ Mease, HD Ochs, RJ Wedgwood	New England Journal of Medicine	1981
Immunoreconstitution by Peripheral Blood Leukocytes in Adenosine Deaminase-deficient Severe Combined Immunodeficiency KC Rich, CM Richman, E Mejias, P Daddona	Journal of Clinical Investigation	1980
Predominance of B-lymphocyte function after cultured thymus fragment therapy in severe combined immunodeficiency disease JF Jones, OF Sieber, VA Fulginiti, H Ochs, H Schulte-Wisserman, R Hong	Clinical Immunology and Immunopathology	1980
The associations and relationships of congenital immune deficiency states and autoimmune phenomena SR Stewart, ME Gershwin	Seminars in Arthritis and Rheumatism	1979
Immune Response of a Patient with Deficiency of the Fourth Component of Complement and Systemic Lupus Erythematosus CG Jackson, HD Ochs, RJ Wedgwood	New England Journal of Medicine	1979
IMMUNE RESPONSE AFTER SPLENECTOMY JL Sullivan, G Schiffman, J Miser, HD Ochs, MR Hammerschlag, E Vichinsky, RJ Wedgwood	The Lancet	1978
Autoimmunity in the relatives of patients with immunodeficiency diseases JM Friedman, PJ Fialkow, SD Davis, HD Ochs, RJ Wedgwood	Clinical & Experimental Immunology	1977
Bacteriophages in Live Virus Vaccines: Lack of Evidence for Effects on the Genome of Rhesus Monkeys JB Milstien, JR Walker, JC Petricciani	Science	1977
Congenital stem cell dysfunction associated with Turner-like phenotype KW Feldman, HD Ochs, TH Price, RJ Wedgwood	The Journal of Pediatrics	1976
The immune response to phichi174 in man. IV. Primary and secondary antibody production in patients with chronic lymphatic leukaemia TJ Hamblin, JV Jones, DB Peacock	Clinical & Experimental Immunology	1975
Defective antibody response to bacteriophage ØX 174 in Down syndrome V Lopez, HD Ochs, HC Thuline, SD Davis, RJ Wedgwood	The Journal of Pediatrics	1975
Defective neutrophil chemotaxis with variant ichthyosis, hyperimmunoglobulinemia E, and recurrent infections SH Pincus, IT Thomas, RA Clark, HD Ochs	The Journal of Pediatrics	1975
Immunodeficiency Syndromes and Gastrointestinal Disease ME Ament	Pediatric Clinics of North America	1975
Management of Patients with Primary Immune Deficiency Syndromes† JV Wells, HH Fudenberg	Australian and New Zealand Journal of Medicine	1974
SERUM IgE CONCENTRATION IN TRISOMY 21 V Lopez	Journal of Intellectual Disability Research	1974
BACTERIOPHAGE INTERACTIONS WITH HIGHER ORGANISMS CR Merril	Transactions of the New York Academy of Sciences	1974
Combined immunodeficiency and reticuloendotheliosis with eosinophilia HD Ochs, SD Davis, E Mickelson, KG Lerner, RJ Wedgwood	The Journal of Pediatrics	1974
Intercellular gene transfer CR Merril, H Stanbro	Zeitschrift für Pflanzenphysiologie	1974
Investigation and Stimulation of Immunity in Cancer Patients G Mathé, R Weiner		1974
The immune response to thetaX 174 in man. I. Primary and secondary antibody production in normal adults DB Peacock, JV Jones, M Gough	Clinical & Experimental Immunology	1973
Surface immunoglobulins on blood lymphocytes of normal and immunodeficient persons studied by the mixed antiglobulin method SD Litwin, H Ochs, B Pollara	Immunology	1973
Arthritis and immunodeficiency JF McLaughlin, J Schaller, RJ Wedgwood	The Journal of Pediatrics	1972
Giardiasis with Malabsorption in X-Linked Agammaglobulinemia HD Ochs, ME Ament, SD Davis	New England Journal of Medicine	1972

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