Rescuing protein conformation: prospects for pharmacological therapy in cystic fibrosis

• Text
• PDF

Abstract

Perspective

Authors

Marina S. Gelman, Ron R. Kopito

Deciphering the genesis and fate of amyloid β-protein yields novel therapies for Alzheimer disease

• Text
• PDF

Abstract

Perspective

Authors

Dennis J. Selkoe

Translational control in the endoplasmic reticulum stress response

• Text
• PDF

Abstract

Perspective

Authors

David Ron

Orchestrating the unfolded protein response in health and disease

• Text
• PDF

Abstract

Perspective

Authors

Randal J. Kaufman

Series Introduction: The cellular response to aggregated proteins associated with human disease

• Text
• PDF

Abstract

Perspective

Authors

David H. Perlmutter

Protein aggregation in disease: a role for folding intermediates forming specific multimeric interactions

• Text
• PDF

Abstract

Perspective

Authors

Arthur Horwich

Bacterial infectious disease control by vaccine development

• Text
• PDF

Abstract

Perspective

Authors

Roy Curtiss III

High-flux mitochondrial cholesterol trafficking, a specialized function of the adrenal cortex

• Text
• PDF

Abstract

Perspective

Authors

Colin Jefcoate

Intracellular cholesterol transport

• Text
• PDF

Abstract

Perspective

Authors

Frederick R. Maxfield, Daniel Wüstner

Regulation and mechanisms of macrophage cholesterol efflux

• Text
• PDF

Abstract

Perspective

Authors

Alan R. Tall, Philippe Costet, Nan Wang