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Rescuing protein conformation: prospects for pharmacological therapy in cystic fibrosis
Marina S. Gelman, Ron R. Kopito
Marina S. Gelman, Ron R. Kopito
Published December 1, 2002
Citation Information:
J Clin Invest.
2002;
110(11)
:1591-1597.
https://doi.org/10.1172/JCI16786
.
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Rescuing protein conformation: prospects for pharmacological therapy in cystic fibrosis
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Marina S. Gelman, Ron R. Kopito
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Figure 1
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Cartoon representation of CFTR structure. Indicated are the transmembrane domains (blue), the two Asn-linked glycans (purple), the “R” domain (green), and the two nucleotide-binding domains (red). N, amino terminus; C, carboxy terminus.