Vanessa Schmidt and colleagues demonstrate that the intracellular sorting receptor SORLA is an important regulator of lipid metabolism…
Published June 20, 2016

Souheil-Antoine Younes and colleagues provide evidence that IL-15 is involved in the expansion of CD8+ T cells in chronic HIV infection...
Published June 20, 2016

Mårten C.G. Winge and colleagues characterize the role of RAC1 in the autoimmune disorder, psoriasis…
Published June 13, 2016

Ramos and colleagues demonstrate that CAR T cells engineered to target κ-light chain-expressing B cells can be infused safely and effectively in human patients with a variety of cancerous B cell malignancies…
Published June 6, 2016

Nicola M. Tomas, Elion Hoxha, and colleagues provide evidence that anti-THSD7A antibodies promote the development of membranous nephropathy...
Published May 23, 2016

Luke Bonser and colleagues characterize the composition and transport of pathogenic, asthma-associated mucus…
Published May 16, 2016

Taichiro Nonaka and colleagues find that AID plays a role in the development of inflammation-driven, non-UV skin cancer
Published March 14, 2016

Haiyang Yu, Mykyta Artomov, Sebastian Brähler and colleagues demonstrate the genetic contribution to the development of focal segmental glomerulosclerosis...
Published February 22, 2016

Charlotte de Winde, Sharon Veenbergen, and colleagues demonstrate that loss of CD37 expression relieves SOCS3-mediated suppression of IL-6 signaling and supports the development of B cell lymphoma…
Published January 19, 2016

Jian Chen and colleagues present evidence that dysfunctional TGF-β/β2SP/CTFC signaling underlies spontaneous tumor development in Beckwith-Wiedemann syndrome…
Published January 19, 2016