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Unconjugated Bilirubin and an Increased Proportion of Bilirubin Monoconjugates in the Bile of Patients with Gilbert's Syndrome and Crigler-Najjar Disease
Johan Fevery, … , Norbert Blanckaert, Karel P. M. Heirwegh
Johan Fevery, … , Norbert Blanckaert, Karel P. M. Heirwegh
Published November 1, 1977
Citation Information: J Clin Invest. 1977;60(5):970-979. https://doi.org/10.1172/JCI108877.
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Research Article

Unconjugated Bilirubin and an Increased Proportion of Bilirubin Monoconjugates in the Bile of Patients with Gilbert's Syndrome and Crigler-Najjar Disease

Abstract

Bilirubin pigments were studied in the bile of 20 normal adults, 25 patients with Gilbert's syndrome, 9 children with Crigler-Najjar disease, and 6 patients with hemolysis, to determine how a deficiency of hepatic bilirubin UDP-glucuronosyltransferase would affect the end products of bilirubin biotransformation.

Authors

Johan Fevery, Norbert Blanckaert, Karel P. M. Heirwegh

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