Philipp S. Wild, Janine F. Felix, Arne Schillert, Alexander Teumer, Ming-Huei Chen, Maarten J.G. Leening, Uwe Völker, Vera Großmann, Jennifer A. Brody, Marguerite R. Irvin, Sanjiv J. Shah, Setia Pramana, Wolfgang Lieb, Reinhold Schmidt, Alice V. Stanton, Dörthe Malzahn, Albert Vernon Smith, Johan Sundström, Cosetta Minelli, Daniela Ruggiero, Leo-Pekka Lyytikäinen, Daniel Tiller, J. Gustav Smith, Claire Monnereau, Marco R. Di Tullio, Solomon K. Musani, Alanna C. Morrison, Tune H. Pers, Michael Morley, Marcus E. Kleber, AortaGen Consortium, Jayashri Aragam, Emelia J. Benjamin, Joshua C. Bis, Egbert Bisping, Ulrich Broeckel, CHARGE-Heart Failure Consortium, Susan Cheng, Jaap W. Deckers, Fabiola Del Greco M, Frank Edelmann, Myriam Fornage, Lude Franke, Nele Friedrich, Tamara B. Harris, Edith Hofer, Albert Hofman, Jie Huang, Alun D. Hughes, Mika Kähönen, KNHI investigators, Jochen Kruppa, Karl J. Lackner, Lars Lannfelt, Rafael Laskowski, Lenore J. Launer, Margrét Leosdottir, Honghuang Lin, Cecilia M. Lindgren, Christina Loley, Calum A. MacRae, Deborah Mascalzoni, Jamil Mayet, Daniel Medenwald, Andrew P. Morris, Christian Müller, Martina Müller-Nurasyid, Stefania Nappo, Peter M. Nilsson, Sebastian Nuding, Teresa Nutile, Annette Peters, Arne Pfeufer, Diana Pietzner, Peter P. Pramstaller, Olli T. Raitakari, Kenneth M. Rice, Fernando Rivadeneira, Jerome I. Rotter, Saku T. Ruohonen, Ralph L. Sacco, Tandaw E. Samdarshi, Helena Schmidt, Andrew S.P. Sharp, Denis C. Shields, Rossella Sorice, Nona Sotoodehnia, Bruno H. Stricker, Praveen Surendran, Simon Thom, Anna M. Töglhofer, André G. Uitterlinden, Rolf Wachter, Henry Völzke, Andreas Ziegler, Thomas Münzel, Winfried März, Thomas P. Cappola, Joel N. Hirschhorn, Gary F. Mitchell, Nicholas L. Smith, Ervin R. Fox, Nicole D. Dueker, Vincent W.V. Jaddoe, Olle Melander, Martin Russ, Terho Lehtimäki, Marina Ciullo, Andrew A. Hicks, Lars Lind, Vilmundur Gudnason, Burkert Pieske, Anthony J. Barron, Robert Zweiker, Heribert Schunkert, Erik Ingelsson, Kiang Liu, Donna K. Arnett, Bruce M. Psaty, Stefan Blankenberg, Martin G. Larson, Stephan B. Felix, Oscar H. Franco, Tanja Zeller, Ramachandran S. Vasan, Marcus Dörr
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Convergence of coronary artery disease genes onto endothelial cell programs.
Schnitzler GR, Kang H, Fang S, Angom RS, Lee-Kim VS, Ma XR, Zhou R, Zeng T, Guo K, Taylor MS, Vellarikkal SK, Barry AE, Sias-Garcia O, Bloemendal A, Munson G, Guckelberger P, Nguyen TH, Bergman DT, Hinshaw S, Cheng N, Cleary B, Aragam K, Lander ES, Finucane HK, Mukhopadhyay D, Gupta RM, Engreitz JM |
Nature | 2024 |
Genetic analysis of cardiac dynamic flow volumes identifies loci mapping aortic root size.
Munroe PB, Aung N, Ramírez J |
Nature Genetics | 2024 |
Sex-stratified genome-wide association and transcriptome-wide Mendelian randomization studies reveal drug targets of heart failure
Yang Q, Yang Q, Wu X, Zheng R, Lin H, Wang S, Joseph J, Sun YV, Li M, Wang T, Zhao Z, Xu M, Lu J, Chen Y, Ning G, Wang W, Bi Y, Zheng J, Xu Y |
Cell reports. Medicine | 2024 |
Deep learning of left atrial structure and function provides link to atrial fibrillation risk.
Pirruccello JP, Di Achille P, Choi SH, Rämö JT, Khurshid S, Nekoui M, Jurgens SJ, Nauffal V, Kany S, Ng K, Friedman SF, Batra P, Lunetta KL, Palotie A, Philippakis AA, Ho JE, Lubitz SA, Ellinor PT |
Nature Communications | 2024 |
Atrial cardiomyopathy revisited—evolution of a concept: a clinical consensus statement of the European Heart Rhythm Association (EHRA) of the ESC, the Heart Rhythm Society (HRS), the Asian Pacific Heart Rhythm Society (APHRS), and the Latin American Heart Rhythm Society (LAHRS)
Goette A, Corradi D, Dobrev D, Aguinaga L, Cabrera JA, Chugh SS, de Groot JR, Soulat-Dufour L, Fenelon G, Hatem SN, Jalife J, Lin YJ, Lip GY, Marcus GM, Murray KT, Pak HN, Schotten U, Takahashi N, Yamaguchi T, Zoghbi WA, Nattel S, Mont L, Akar JG, Akoum N, Althoff T, Diaz JC, Guichard JB, Jadidi A, Kalman J, Lim H, Teixeira RA |
Europace | 2024 |
Dilated Cardiomyopathy: A Genetic Journey from Past to Future
Newman NA, Burke MA |
International Journal of Molecular Sciences | 2024 |
Molecular convergence of risk variants for congenital heart defects leveraging a regulatory map of the human fetal heart
Ma XR, Conley SD, Kosicki M, Bredikhin D, Cui R, Tran S, Sheth MU, Qiu WL, Chen S, Kundu S, Kang HY, Amgalan D, Munger CJ, Duan L, Dang K, Rubio OM, Kany S, Zamirpour S, DePaolo J, Padmanabhan A, Olgin J, Damrauer S, Andersson R, Gu M, Priest JR, Quertermous T, Qiu X, Rabinovitch M, Visel A, Pennacchio L, Kundaje A, Glass IA, Gifford CA, Pirruccello JP, Goodyer WR, Engreitz JM |
medRxiv | 2024 |
Genome-Wide Analysis of Left Ventricular Maximum Wall Thickness in the UK Biobank Cohort Reveals a Shared Genetic Background With Hypertrophic Cardiomyopathy
Aung N, Lopes LR, van Duijvenboden S, Harper AR, Goel A, Grace C, Ho CY, Weintraub WS, Kramer CM, Neubauer S, Watkins HC, Petersen SE, Munroe PB |
Circulation. Genomic and precision medicine | 2023 |
Clinical and genetic associations of deep learning-derived cardiac magnetic resonance-based left ventricular mass
Khurshid S, Lazarte J, Pirruccello JP, Weng LC, Choi SH, Hall AW, Wang X, Friedman SF, Nauffal V, Biddinger KJ, Aragam KG, Batra P, Ho JE, Philippakis AA, Ellinor PT, Lubitz SA |
Nature Communications | 2023 |
Cfdp1 Is Essential for Cardiac Development and Function.
Giardoglou P, Deloukas P, Dedoussis G, Beis D |
Cells | 2023 |
Using Genomics to Identify Novel Therapeutic Targets for Aortic Disease
Raghavan A, Pirruccello JP, Ellinor PT, Lindsay ME |
Arteriosclerosis, thrombosis, and vascular biology | 2023 |
Identification of Clinical Drivers of Left Atrial Enlargement through Genomics of Left Atrial Size
Agrawal V, Manouchehri A, Vaitinadin NS, Shi M, Bagheri M, Gupta DK, Kullo IJ, Luo Y, McNally EM, Puckelwartz MJ, Ferguson JF, Wells QS, Mosley JD |
Circulation. Heart failure | 2023 |
Association of rs35006907 Polymorphism with Risk of Dilated Cardiomyopathy in Han Chinese Population.
Yang C, Chen F, Li S, Zeng X, Wang S, Lan J |
2023 | |
Heart-specific DNA methylation analysis in plasma for the investigation of myocardial damage
J Ren, L Jiang, X Liu, Y Liao, X Zhao, F Tang, H Yu, Y Shao, J Wang, L Wen, L Song |
Journal of Translational Medicine | 2022 |
Positive selection acts on regulatory genetic variants in populations of European ancestry that affect ALDH2 gene expression
H Schaschl, T Göllner, D Morris |
Scientific Reports | 2022 |
Genetic and environmental determinants of diastolic heart function
M Thanaj, J Mielke, K McGurk, W Bai, N Savioli, A de Marvao, H Meyer, L Zeng, F Sohler, R Lumbers, M Wilkins, J Ware, C Bender, D Rueckert, A MacNamara, D Freitag, D ORegan |
2022 | |
High heritability of ascending aortic diameter and trans-ancestry prediction of thoracic aortic disease
C Tcheandjieu, K Xiao, H Tejeda, J Lynch, S Ruotsalainen, T Bellomo, M Palnati, R Judy, D Klarin, R Kember, S Verma, G Abecasis, A Baras, Michael, G Coppola, A Deubler, A Economides, K Karalis, L Lotta, J Overton, J Reid, K Siminovitch, A Shuldiner, C Beechert, C Forsythe, E Fuller, Z Gu, M Lattari, A Lopez, M Padilla, M Pradhan, K Manoochehri, T Schleicher, L Widom, S Wolf, R Ulloa, A Averitt, N Banerjee, D Li, S Malhotra, D Sharma, J Staples, X Bai, S Balasubramanian, S Bao, B Boutkov, S Chen, G Eom, L Habegger, A Hawes, S Khalid, O Krasheninina, R Lanche, A Mansfield, E Maxwell, G Mitra, M Nafde, S OKeeffe, M Orelus, R Panea, T Polanco, A Rasool, W Salerno, K Sun, J Xin, J Backman, A Damask, L Dobbyn, M Ferreira, A Ghosh, C Gillies, L Gurski, E Jorgenson, H Kang, M Kessler, J Kosmicki, A Li, N Lin, D Liu, A Locke, J Marchini, A Marcketta, J Mbatchou, A Moscati, C Paulding, C Sidore, E Stahl, K Watanabe, B Ye, B Zhang, A Ziyatdinov, M Jones, J Mighty, L Mitnaul, A Palotie, M Daly, M Ritchie, D Rader, M Rivas, T Assimes, P Tsao, S Damrauer, J Priest |
Nature Genetics | 2022 |
Genome-wide association analysis reveals insights into the genetic architecture of right ventricular structure and function
N Aung, J Vargas, C Yang, K Fung, M Sanghvi, S Piechnik, S Neubauer, A Manichaikul, J Rotter, K Taylor, J Lima, D Bluemke, S Kawut, S Petersen, P Munroe |
Nature Genetics | 2022 |
Genetic analysis of right heart structure and function in 40,000 people
J Pirruccello, P Achille, V Nauffal, M Nekoui, S Friedman, M Klarqvist, M Chaffin, L Weng, J Cunningham, S Khurshid, C Roselli, H Lin, S Koyama, K Ito, Y Kamatani, I Komuro, K Matsuda, Y Yamanashi, Y Furukawa, T Morisaki, Y Murakami, Y Kamatani, K Mutu, A Nagai, W Obara, K Yamaji, K Takahashi, S Asai, Y Takahashi, T Suzuki, N Sinozaki, H Yamaguchi, S Minami, S Murayama, K Yoshimori, S Nagayama, D Obata, M Higashiyama, A Masumoto, Y Koretsune, S Jurgens, E Benjamin, P Batra, P Natarajan, K Ng, U Hoffmann, S Lubitz, J Ho, M Lindsay, A Philippakis, P Ellinor |
Nature Genetics | 2022 |
Low Level of PALMD Contributes to the Metastasis of Uveal Melanoma.
Cai MY, Xu YL, Rong H, Yang H |
Frontiers in Oncology | 2022 |
Genetic Determinants of Body Mass Index and Fasting Glucose Are Mediators of Grade 1 Diastolic Dysfunction.
Vaitinadin NS, Shi M, Shaffer CM, Farber-Eger E, Lowery BD, Agrawal V, Gupta DK, Roden DM, Wells QS, Mosley JD |
Journal of the American Heart Association | 2022 |
Genetics and mechanisms of thoracic aortic disease.
Chou E, Pirruccello JP, Ellinor PT, Lindsay ME |
Nature reviews. Cardiology | 2022 |
Biomarkers in HFpEF for Diagnosis, Prognosis, and Biological Phenotyping.
Eltelbany M, Shah P, deFilippi C |
Current Heart Failure Reports | 2022 |
CFDP1 promotes hepatocellular carcinoma progression through activating NEDD4/PTEN/PI3K/AKT signaling pathway
Zhou Y, Qiu J, Liu S, Wang P, Ma D, Zhang G, Cao Y, Hu L, Wang Z, Wu J, Jiang C |
Cancer Medicine | 2022 |
Spatially Distinct Genetic Determinants of Aortic Dimensions Influence Risks of Aneurysm and Stenosis
Nekoui M, Pirruccello JP, Di Achille P, Choi SH, Friedman SN, Nauffal V, Ng K, Batra P, Ho JE, Philippakis AA, Lubitz SA, Lindsay ME, Ellinor PT |
Journal of the American College of Cardiology | 2022 |
Towards precision medicine in heart failure
CS Weldy, EA Ashley |
Nature Reviews Cardiology | 2021 |
The genetics of human performance
DS Kim, MT Wheeler, EA Ashley |
Nature Reviews Genetics | 2021 |
Progress and Research Priorities in Imaging Genomics for Heart and Lung Disease: Summary of an NHLBI Workshop
M Nayor, L Shen, GM Hunninghake, P Kochunov, RG Barr, DA Bluemke, U Broeckel, P Caravan, S Cheng, PS de Vries, U Hoffmann, M Kolossváry, H Li, J Luo, EM McNally, G Thanassoulis, DK Arnett, RS Vasan |
Circulation. Cardiovascular imaging | 2021 |
Enhancer-associated aortic valve stenosis risk locus 1p21.2 alters NFATC2 binding site and promotes fibrogenesis
A Chignon, M Rosa, MC Boulanger, D Argaud, R Devillers, V Bon-Baret, G Mkannez, Z Li, A Rufiange, N Gaudreault, D Gosselin, S Thériault, Y Bossé, P Mathieu |
iScience | 2021 |
Genetic approaches toward understanding the individual variation in cardiac structure, function and responses to exercise training
M Kim, SK Kim |
The Korean Journal of Physiology & Pharmacology | 2021 |
Chromatin Accessibility of Human Mitral Valves and Functional Assessment of MVP Risk Loci
S Kyryachenko, A Georges, M Yu, T Barrandou, L Guo, P Bruneval, T Rubio, J Gronwald, H Baraki, I Kutschka, KK Aras, IR Efimov, RA Norris, N Voigt, N Bouatia-Naji |
Circulation research | 2021 |
Association of 3 single nucleotide polymorphisms of the eighth chromosome with remodeling of the myocardium and carotid arteries in the Kazakh population
K Raushan, V Benberin, T Vochshenkova, D Babenko, A Sibagatova |
Medicine | 2021 |
Deep learning enables genetic analysis of the human thoracic aorta
JP Pirruccello, MD Chaffin, EL Chou, SJ Fleming, H Lin, M Nekoui, S Khurshid, SF Friedman, AG Bick, A Arduini, LC Weng, SH Choi, AD Akkad, P Batra, NR Tucker, AW Hall, C Roselli, EJ Benjamin, SK Vellarikkal, RM Gupta, CM Stegmann, D Juric, JR Stone, RS Vasan, JE Ho, U Hoffmann, SA Lubitz, AA Philippakis, ME Lindsay, PT Ellinor |
Nature Genetics | 2021 |
Genome-wide association and Mendelian randomisation analysis provide insights into the pathogenesis of heart failure
S Shah, A Henry, C Roselli, H Lin, G Sveinbjörnsson, G Fatemifar, ÅK Hedman, JB Wilk, MP Morley, MD Chaffin, A Helgadottir, N Verweij, A Dehghan, P Almgren, C Andersson, KG Aragam, J Ärnlöv, JD Backman, ML Biggs, HL Bloom, J Brandimarto, MR Brown, L Buckbinder, DJ Carey, DI Chasman, X Chen, X Chen, J Chung, W Chutkow, JP Cook, GE Delgado, S Denaxas, AS Doney, M Dörr, SC Dudley, ME Dunn, G Engström, T Esko, SB Felix, C Finan, I Ford, M Ghanbari, S Ghasemi, V Giedraitis, F Giulianini, JS Gottdiener, S Gross, DF Guðbjartsson, R Gutmann, CM Haggerty, P van der Harst, CL Hyde, E Ingelsson, JW Jukema, M Kavousi, KT Khaw, ME Kleber, L Køber, A Koekemoer, C Langenberg, L Lind, CM Lindgren, B London, LA Lotta, RC Lovering, J Luan, P Magnusson, A Mahajan, KB Margulies, W März, O Melander, IR Mordi, T Morgan, AD Morris, AP Morris, AC Morrison, MW Nagle, CP Nelson, A Niessner, T Niiranen, ML ODonoghue, AT Owens, CN Palmer, HM Parry, M Perola, E Portilla-Fernandez, BM Psaty, KM Rice, PM Ridker, SP Romaine, JI Rotter, P Salo, V Salomaa, J van Setten, AA Shalaby, DT Smelser, NL Smith, S Stender, DJ Stott, P Svensson, ML Tammesoo, KD Taylor, M Teder-Laving, A Teumer, G Thorgeirsson, U Thorsteinsdottir, C Torp-Pedersen, S Trompet, B Tyl, AG Uitterlinden, A Veluchamy, U Völker, AA Voors, X Wang, NJ Wareham, D Waterworth, PE Weeke, R Weiss, KL Wiggins, H Xing, LM Yerges-Armstrong, B Yu, F Zannad, JH Zhao, H Hemingway, NJ Samani, JJ McMurray, J Yang, PM Visscher, C Newton-Cheh, A Malarstig, H Holm, SA Lubitz, N Sattar, MV Holmes, TP Cappola, FW Asselbergs, AD Hingorani, K Kuchenbaecker, PT Ellinor, CC Lang, K Stefansson, JG Smith, RS Vasan, DI Swerdlow, RT Lumbers |
Nature Communications | 2020 |
Genomic inbreeding trends, influential sire lines and selection in the global Thoroughbred horse population
BA McGivney, H Han, LR Corduff, LM Katz, T Tozaki, DE MacHugh, EW Hill |
Scientific Reports | 2020 |
Lymphangiogenic therapy prevents cardiac dysfunction by ameliorating inflammation and hypertension
LJ Song, X Chen, TA Swanson, B LaViolette, J Pang, T Cunio, MW Nagle, S Asano, K Hales, A Shipstone, H Sobon, SD Al-Harthy, Y Ahn, S Kreuser, A Robertson, C Ritenour, F Voigt, M Boucher, F Sun, WC Sessa, RJ Flach |
eLife | 2020 |
Aptamer-Based Proteomic Platform Identifies Novel Protein Predictors of Incident Heart Failure and Echocardiographic Traits
M Nayor, MI Short, H Rasheed, H Lin, C Jonasson, Q Yang, K Hveem, JF Felix, AC Morrison, PS Wild, MP Morley, TP Cappola, MD Benson, D Ngo, S Sinha, MJ Keyes, D Shen, TJ Wang, MG Larson, BM Brumpton, RE Gerszten, T Omland, RS Vasan |
Circulation. Heart failure | 2020 |
Objectives, design and main findings until 2020 from the Rotterdam Study
MA Ikram, G Brusselle, M Ghanbari, A Goedegebure, MK Ikram, M Kavousi, BC Kieboom, CC Klaver, RJ de Knegt, AI Luik, TE Nijsten, RP Peeters, FJ van Rooij, BH Stricker, AG Uitterlinden, MW Vernooij, T Voortman |
European Journal of Epidemiology | 2020 |
Analysis of cardiac magnetic resonance imaging in 36,000 individuals yields genetic insights into dilated cardiomyopathy
JP Pirruccello, A Bick, M Wang, M Chaffin, S Friedman, J Yao, X Guo, BA Venkatesh, KD Taylor, WS Post, S Rich, JA Lima, JI Rotter, A Philippakis, SA Lubitz, PT Ellinor, AV Khera, S Kathiresan, KG Aragam |
Nature Communications | 2020 |
When genetic burden reaches threshold
R Walsh, R Tadros, CR Bezzina |
European Heart Journal | 2020 |
Genetic and functional insights into the fractal structure of the heart
HV Meyer, TJ Dawes, M Serrani, W Bai, P Tokarczuk, J Cai, A de Marvao, A Henry, RT Lumbers, J Gierten, T Thumberger, J Wittbrodt, JS Ware, D Rueckert, PM Matthews, SK Prasad, ML Costantino, SA Cook, E Birney, DP ORegan |
Nature | 2020 |
The polygenic architecture of left ventricular mass mirrors the clinical epidemiology
JD Mosley, RT Levinson, E Farber-Eger, TL Edwards, JN Hellwege, AM Hung, A Giri, MM Shuey, CM Shaffer, M Shi, EL Brittain, WK Chung, IJ Kullo, AM Arruda-Olson, GP Jarvik, EB Larson, DR Crosslin, MS Williams, KM Borthwick, H Hakonarson, JC Denny, TJ Wang, CM Stein, DM Roden, QS Wells |
Scientific Reports | 2020 |
Common Genetic Variation Indicates Separate Causes for Periventricular and Deep White Matter Hyperintensities
NJ Armstrong, KA Mather, M Sargurupremraj, MJ Knol, R Malik, CL Satizabal, LR Yanek, W Wen, VG Gudnason, ND Dueker, LT Elliott, E Hofer, J Bis, N Jahanshad, S Li, MA Logue, M Luciano, M Scholz, AV Smith, S Trompet, D Vojinovic, R Xia, F Alfaro-Almagro, D Ames, N Amin, P Amouyel, AS Beiser, H Brodaty, IJ Deary, C Fennema-Notestine, PG Gampawar, R Gottesman, L Griffanti, CR Jack, M Jenkinson, J Jiang, BG Kral, JB Kwok, L Lampe, DC Liewald, P Maillard, J Marchini, ME Bastin, B Mazoyer, L Pirpamer, JR Romero, GV Roshchupkin, PR Schofield, ML Schroeter, DJ Stott, A Thalamuthu, J Trollor, C Tzourio, J van der Grond, MW Vernooij, VA Witte, MJ Wright, Q Yang, Z Morris, S Siggurdsson, B Psaty, A Villringer, H Schmidt, AK Haberg, CM van Duijn, JW Jukema, M Dichgans, RL Sacco, CB Wright, WS Kremen, LC Becker, PM Thompson, TH Mosley, JM Wardlaw, MA Ikram, HH Adams, S Seshadri, PS Sachdev, SM Smith, L Launer, W Longstreth, C DeCarli, R Schmidt, M Fornage, S Debette, PA Nyquist |
Stroke; a journal of cerebral circulation | 2020 |
Genome-wide association and multi-omic analyses reveal ACTN2 as a gene linked to heart failure
M Arvanitis, E Tampakakis, Y Zhang, W Wang, A Auton, D Dutta, S Glavaris, A Keramati, N Chatterjee, NC Chi, B Ren, WS Post, A Battle |
Nature Communications | 2020 |
Big Data Approaches in Heart Failure Research
JD Lanzer, F Leuschner, R Kramann, RT Levinson, J Saez-Rodriguez |
Current Heart Failure Reports | 2020 |
Epigenomes of Human Hearts Reveal New Genetic Variants Relevant for Cardiac Disease and Phenotype
Tan WL, Anene-Nzelu CG, Wong E, Lee CJ, Tan HS, Tang SJ, Perrin A, Wu KX, Wenhao Z, Ashburn RJ, Pan B, Yin LM, Autio MI, Morley MP, Tam WL, Cheung C, Margulies KB, Chen L, Cappola TP, Loh M, Chambers J, Prabhakar S, Foo RS |
Circulation research | 2020 |
Genome Wide Meta-Analysis identifies common genetic signatures shared by heart function and Alzheimer’s disease
ME Sáez, A González-Pérez, B Hernández-Olasagarre, A Beà, S Moreno-Grau, I de Rojas, G Monté-Rubio, A Orellana, S Valero, JX Comella, D Sanchís, A Ruiz |
Scientific Reports | 2019 |
Genes Whose Gain or Loss-of-Function Increases Endurance Performance in Mice: A Systematic Literature Review
FY Nezhad, SA Verbrugge, M Schönfelder, L Becker, MH de Angelis, H Wackerhage |
Frontiers in physiology | 2019 |
TMEM16A is implicated in the regulation of coronary flow and is altered in hypertension
HR Page, T Dalsgaard, SN Baldwin, TA Jepps, O Povstyan, SP Olesen, IA Greenwood |
British Journal of Pharmacology | 2019 |
Phenotypic Refinement of Heart Failure in a National Biobank Facilitates Genetic Discovery
KG Aragam, M Chaffin, RT Levinson, G McDermott, SH Choi, MB Shoemaker, ME Haas, LC Weng, ME Lindsay, JG Smith, C Newton-Cheh, DM Roden, B London, QS Wells, PT Ellinor, S Kathiresan, SA Lubitz, HL Bloom, SC Dudley, AA Shalaby, R Weiss, R Gutmann, S Saba |
Circulation | 2019 |
Genetic overlap between birthweight and adult cardiometabolic diseases has implications for genomic medicine
F Tekola-Ayele, A Lee, T Workalemahu, W Zhang, D Shrestha, AT Amare, M Ouidir |
Scientific Reports | 2019 |
Cardioprotective Effects of MTSS1 Enhancer Variants
MP Morley, X Wang, R Hu, J Brandimarto, NR Tucker, JF Felix, NL Smith, P van der Harst, PT Ellinor, KB Margulies, K Musunuru, TP Cappola |
Circulation | 2019 |
Differential interactions of missing in metastasis and insulin receptor tyrosine kinase substrate with RAB proteins in the endocytosis of CXCR4
L Li, SS Baxter, P Zhao, N Gu, |
The Journal of biological chemistry | 2019 |
Isoproterenol-Induced Cardiac Diastolic Dysfunction in Mice: A Systems Genetics Analysis
J Wang, A Huertas-Vazquez, Y Wang, AJ Lusis |
Frontiers in Cardiovascular Medicine | 2019 |
Genome-Wide Analysis of Left Ventricular Image-Derived Phenotypes Identifies Fourteen Loci Associated With Cardiac Morphogenesis and Heart Failure Development
N Aung, JD Vargas, C Yang, CP Cabrera, HR Warren, K Fung, E Tzanis, MR Barnes, JI Rotter, KD Taylor, AW Manichaikul, JA Lima, DA Bluemke, SK Piechnik, S Neubauer, PB Munroe, SE Petersen |
Circulation | 2019 |
Region-based interaction detection in genome-wide case-control studies
S Zhang, W Jiang, RC Ma, W Yu |
BMC Medical Genomics | 2019 |
Nitric oxide signalling in cardiovascular health and disease
C Farah, LY Michel, JL Balligand |
Nature Reviews Cardiology | 2018 |
Update on Chronic Kidney Disease Mineral and Bone Disorder in Cardiovascular Disease
J Lunyera, JJ Scialla |
Seminars in Nephrology | 2018 |
Genome-wide analysis yields new loci associating with aortic valve stenosis
A Helgadottir, G Thorleifsson, S Gretarsdottir, OA Stefansson, V Tragante, RB Thorolfsdottir, I Jonsdottir, T Bjornsson, V Steinthorsdottir, N Verweij, JB Nielsen, W Zhou, L Folkersen, A Martinsson, M Heydarpour, S Prakash, G Oskarsson, T Gudbjartsson, A Geirsson, I Olafsson, EL Sigurdsson, P Almgren, O Melander, A Franco-Cereceda, A Hamsten, L Fritsche, M Lin, B Yang, W Hornsby, D Guo, CM Brummett, G Abecasis, M Mathis, D Milewicz, SC Body, P Eriksson, CJ Willer, K Hveem, C Newton-Cheh, JG Smith, R Danielsen, G Thorgeirsson, U Thorsteinsdottir, DF Gudbjartsson, H Holm, K Stefansson |
Nature Communications | 2018 |
Scientific Contributions of Population-Based Studies to Cardiovascular Epidemiology in the GWAS Era
W Lieb, RS Vasan |
Frontiers in Cardiovascular Medicine | 2018 |
A transcriptome-wide association study identifies PALMD as a susceptibility gene for calcific aortic valve stenosis
S Thériault, N Gaudreault, M Lamontagne, M Rosa, MC Boulanger, D Messika-Zeitoun, MA Clavel, R Capoulade, F Dagenais, P Pibarot, P Mathieu, Y Bossé |
Nature Communications | 2018 |
Electronic health records: the next wave of complex disease genetics
BN Wolford, CJ Willer, I Surakka |
Human Molecular Genetics | 2018 |
Imaging Endophenotypes of Stroke as a Target for Genetic Studies
X Jian, M Fornage |
Stroke; a journal of cerebral circulation | 2018 |
Genome‐Wide Associations of Global Electrical Heterogeneity ECG Phenotype: The ARIC (Atherosclerosis Risk in Communities) Study and CHS (Cardiovascular Health Study)
LG Tereshchenko, N Sotoodehnia, CM Sitlani, FN Ashar, M Kabir, ML Biggs, MP Morley, JW Waks, EZ Soliman, AE Buxton, T BieringSørensen, SD Solomon, WS Post, TP Cappola, DS Siscovick, DE Arking |
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease | 2018 |
Molecular Epidemiology of Heart Failure
JG Smith |
JACC: Basic to Translational Science | 2017 |
Three-dimensional cardiovascular imaging-genetics: a mass univariate framework
C Biffi, A de Marvao, MI Attard, TJ Dawes, N Whiffin, W Bai, W Shi, C Francis, H Meyer, R Buchan, SA Cook, D Rueckert, DP ORegan, R Murphy |
Bioinformatics | 2017 |
Quantitative trait mapping in Diversity Outbred mice identifies two genomic regions associated with heart size
JR Shorter, W Huang, JY Beak, K Hua, DM Gatti, FP de Villena, D Pomp, BC Jensen |
Mammalian Genome | 2017 |