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Myeloid-derived suppressor cells in the tumor microenvironment: expect the unexpected
Douglas Marvel, Dmitry I. Gabrilovich
Douglas Marvel, Dmitry I. Gabrilovich
Published July 13, 2015
Citation Information: J Clin Invest. 2015;125(9):3356-3364. https://doi.org/10.1172/JCI80005.
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Myeloid-derived suppressor cells in the tumor microenvironment: expect the unexpected

Abstract

Our understanding of the role of myeloid-derived suppressor cells (MDSCs) in cancer is becoming increasingly complex. In addition to their eponymous role in suppressing immune responses, they directly support tumor growth, differentiation, and metastasis in a number of ways that are only now beginning to be appreciated. It is because of this increasingly complex role that these cells may become an important factor in the treatment of human cancer. In this Review, we discuss the most pertinent and controversial issues of MDSC biology and their role in promoting cancer progression and highlight how these cells may be used in the clinic, both as prognostic factors and as therapeutic targets.

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Douglas Marvel, Dmitry I. Gabrilovich

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Targeting myeloid-derived suppressor cells to enhance natural killer cell-based immunotherapy
Joshi S, Sharabi A 		Pharmacology & Therapeutics 2022
Targeted regulation of tumor microenvironment through the inhibition of MDSCs by curcumin loaded self-assembled nano-filaments
Wang T, Wang J, Jiang H, Ni M, Zou Y, Chen Y, Wu T, Ding D, Xu H, Li X 		2022
Immune Microenvironment in Osteosarcoma: Components, Therapeutic Strategies and Clinical Applications
Zhu T, Han J, Yang L, Cai Z, Sun W, Hua Y, Xu J 		Frontiers in immunology 2022
Notch-Signaling Deregulation Induces Myeloid-Derived Suppressor Cells in T-Cell Acute Lymphoblastic Leukemia
Grazioli P, Orlando A, Giordano N, Noce C, Peruzzi G, Abdollahzadeh B, Screpanti I, Campese AF 		Frontiers in immunology 2022
Discovery of efficacy biomarkers for non-small cell lung cancer with first-line anti-PD-1 immunotherapy by 
data-independent acquisition mass spectrometry
Chao Y, Jiang W, Wang X, Wang X, Song J, Chen C, Zhou J, Huang Q, Hu J, Song Y 		Clinical & Experimental Immunology 2022
Targeting of Nrf2 improves antitumoral responses by human NK cells, TIL and CAR T cells during oxidative stress.
Renken S, Nakajima T, Magalhaes I, Mattsson J, Lundqvist A, Arnér ESJ, Kiessling R, Wickström SL 		Journal for ImmunoTherapy of Cancer 2022
3,3′-Diindolylmethane improves antitumor immune responses of PD-1 blockade via inhibiting myeloid-derived suppressor cells
Sun Q, Xiao L, Cui Z, Yang Y, Ma J, Huang Z, Zhang J, Chen J 		Chinese medicine 2022
Crosstalk of RNA Adenosine Modification-Related Subtypes, Establishment of a Prognostic Model, and Immune Infiltration Characteristics in Ovarian Cancer
Ni X, Chen C, Cui G, Ding W, Liu J 		Frontiers in immunology 2022
Activation of cGAS‐STING by Lethal Malaria N67C Dictates Immunity and Mortality through Induction of CD11b+Ly6Chi Proinflammatory Monocytes
Du Y, Luo Y, Hu Z, Lu J, Liu X, Xing C, Wu J, Duan T, Chu J, Wang HY, Su X, Yu X, Wang R 		Advanced Science 2022
TIE-2 Signaling Activation by Angiopoietin 2 On Myeloid-Derived Suppressor Cells Promotes Melanoma-Specific T-cell Inhibition
Marguier A, Laheurte C, Lecoester B, Malfroy M, Boullerot L, Renaudin A, Seffar E, Kumar A, Nardin C, Aubin F, Adotevi O 		Frontiers in immunology 2022
Aging Affects the Role of Myeloid-Derived Suppressor Cells in Alloimmunity
Schroeter A, Roesel MJ, Matsunaga T, Xiao Y, Zhou H, Tullius SG 		Frontiers in immunology 2022
Beneficial Modulatory Effects of Treatment With Bone Marrow Lysate on Hematopoietic Stem Cells and Myeloid Cells in Tumor-Bearing Mice
Salem ML, El-Bakry KA, Moubark EH, Sobh A, Khalil SM 		British journal of biomedical science 2022
Novel Systemic Treatment Modalities Including Immunotherapy and Molecular Targeted Therapy for Recurrent and Metastatic Head and Neck Squamous Cell Carcinoma
Ghosh S, Shah PA, Johnson FM 		International journal of molecular sciences 2022
The Role of Beetroot Extract in Overcoming Chemoresistance of Neoadjuvant Adriamycin Cyclophosphamide Regimen by Targeting Immune Response in Tumor Microenvironment: A Preclinical Study in Mammary Adenocarcinoma Rats.
Susilowati S, Istiadi H, Suhartono S, Prajoko YW, Riwanto I, Susilaningsih N, Suharti C 		Asian Pacific Journal of Cancer Prevention 2022
Interaction between microbiota and immunity and its implication in colorectal cancer.
Xing C, Du Y, Duan T, Nim K, Chu J, Wang HY, Wang RF 		Frontiers in immunology 2022
Combinatorial therapeutic approaches of photodynamic therapy and immune checkpoint blockade for colon cancer treatment.
Hao Y, Chung CK, Gu Z, Schomann T, Dong X, Veld RVHI', Camps MGM, Ten Dijke P, Ossendorp FA, Cruz LJ 		2022
Ablation of NLRP3 inflammasome rewires MDSC function and promotes tumor regression
Papafragkos I, Grigoriou M, Boon L, Kloetgen A, Hatzioannou A, Verginis P 		Frontiers in immunology 2022
Prognostic significance of inflammatory markers LMR, PLR, MPV, FIB in intermediate-and high-risk papillary thyroid carcinoma.
Li C, Li J, Li S, Zhao Y, Liu G, Du R, Dionigi G, Liang N, Sun H 		Frontiers in Endocrinology 2022
Breast cancer microenvironment and obesity: challenges for therapy.
Hillers-Ziemer LE, Kuziel G, Williams AE, Moore BN, Arendt LM 		Cancer metastasis reviews 2022
Circadian Rhythm Disruption Increases Tumor Growth Rate and Accumulation of Myeloid-Derived Suppressor Cells
Roberts NT, MacDonald CR, Mohammadpour H, Antoch MP, Repasky EA 		2022
Immune status for monitoring and treatment of bladder cancer
Pan S, Li S, Zhan Y, Chen X, Sun M, Liu X, Wu B, Li Z, Liu B 		Frontiers in immunology 2022
New Perspectives on Myeloid-Derived Suppressor Cells and Their Emerging Role in Haematology
Bizymi N, Matthaiou AM, Matheakakis A, Voulgari I, Aresti N, Zavitsanou K, Karasachinidis A, Mavroudi I, Pontikoglou C, Papadaki HA 		Journal of Clinical Medicine 2022
Peripheral Lymphocyte Counts and Lymphocyte-Related Inflammation Indicators During Radiotherapy for Pelvic Malignancies: Temporal Characterization and Dosimetric Predictors.
Xiang X, Li N, Ding Z, Dai Z, Jin J 		Technology in cancer research & treatment 2022
Myeloid-derived suppressor cells: an emerging target for anticancer immunotherapy.
Wu Y, Yi M, Niu M, Mei Q, Wu K 		Molecular Cancer 2022
Targeting depletion of myeloid-derived suppressor cells potentiates PD-L1 blockade efficacy in gastric and colon cancers
Tang Y, Zhou C, Li Q, Cheng X, Huang T, Li F, He L, Zhang B, Tu S 		OncoImmunology 2022
NLRP1 in Cutaneous SCCs: An Example of the Complex Roles of Inflammasomes in Cancer Development.
Di Filippo M, Hennig P, Karakaya T, Slaufova M, Beer HD 		International journal of molecular sciences 2022
Targeting myeloid suppressive cells revives cytotoxic anti-tumor responses in pancreatic cancer.
Sarhan D, Eisinger S, He F, Bergsland M, Pelicano C, Driescher C, Westberg K, Benitez II, Humoud R, Palano G, Li S, Carannante V, Muhr J, Önfelt B, Schlisio S, Ravetch JV, Heuchel R, Löhr MJ, Karlsson MCI 		iScience 2022
The roles of metabolic profiles and intracellular signaling pathways of tumor microenvironment cells in angiogenesis of solid tumors.
Zalpoor H, Aziziyan F, Liaghat M, Bakhtiyari M, Akbari A, Nabi-Afjadi M, Forghaniesfidvajani R, Rezaei N 		Cell communication and signaling : CCS 2022
ARID1A loss induces polymorphonuclear myeloid-derived suppressor cell chemotaxis and promotes prostate cancer progression.
Li N, Liu Q, Han Y, Pei S, Cheng B, Xu J, Miao X, Pan Q, Wang H, Guo J, Wang X, Zhang G, Lian Y, Zhang W, Zang Y, Tan M, Li Q, Wang X, Xiao Y, Hu G, Jiang J, Huang H, Qin J 		Nature Communications 2022
Bone Marrow Immune Microenvironment in Myelodysplastic Syndromes
Kouroukli O, Symeonidis A, Foukas P, Maragkou MK, Kourea EP 		Cancers 2022
Mechanism of exosomes in the tumor microenvironment in the abscopal effect (Review)
Kuang G, Wang Z, Luo C, Luo J, Wang J 		International journal of oncology 2022
Improving head and neck cancer therapies by immunomodulation of the tumour microenvironment.
Ruffin AT, Li H, Vujanovic L, Zandberg DP, Ferris RL, Bruno TC 		Nature reviews. Cancer 2022
Bone Metastasis of Breast Cancer: Molecular Mechanisms and Therapeutic Strategies
Pang L, Gan C, Xu J, Jia Y, Chai J, Huang R, Li A, Ge H, Yu S, Cheng H 		Cancers 2022
The mononuclear phagocyte system in hepatocellular carcinoma
Qiao DR, Shan GY, Wang S, Cheng JY, Yan WQ, Li HJ 		World Journal of Gastroenterology 2022
Heterogeneity of neutrophils in cancer: one size does not fit all
Chen S, Zhang Q, Lu L, Xu C, Li J, Zha J, Ma F, Luo HR, Hsu AY 		Cancer biology & medicine 2022
Differentiation and Immunological Function of MDSC-Derived Dendritic Cells
Ding Z, Zhang Y 		2022
Tumor microenvironment enriches the stemness features: the architectural event of therapy resistance and metastasis
Nallasamy P, Nimmakayala RK, Parte S, Are AC, Batra SK, Ponnusamy MP 		Molecular Cancer 2022
Immunophenotype and function of circulating myeloid derived suppressor cells in COVID-19 patients
Kiaee F, Jamaati H, Shahi H, Roofchayee ND, Varahram M, Folkerts G, Garssen J, Adcock IM, Mortaz E 		Scientific Reports 2022
An Overview of Epithelial-to-Mesenchymal Transition and Mesenchymal-to-Epithelial Transition in Canine Tumors: How Far Have We Come?
Armando F, Mazzola F, Ferrari L, Corradi A 		Veterinary Sciences 2022
S‐1 eliminates MDSCs and enhances the efficacy of PD‐1 blockade via regulation of tumor‐derived Bv8 and S100A8 in thoracic tumor
Nguyen NT, Mitsuhashi A, Ogino H, Kozai H, Yoneda H, Afroj T, Sato S, Nokihara H, Shinohara T, Nishioka Y 		Cancer Science 2022
Monocytic Myeloid-Derived Suppressor Cells from Tumor Tissue Are a Differentiated Cell with Limited Fate Plasticity
Calvert RD, Fleet JC, Fournier PG, Juarez P, Burcham GN, Haverkamp JM, Guise TA, Ratliff TL, Elzey BD 		ImmunoHorizons 2022
Chimeric antigen receptor engineered NK cellular immunotherapy overcomes the selection of T-cell escape variant cancer cells
MY Lee, Y Robbins, C Sievers, J Friedman, HA Sater, PE Clavijo, N Judd, E Tsong, C Silvin, P Soon-Shiong, MR Padget, J Schlom, J Hodge, C Hinrichs, C Allen 		Journal for ImmunoTherapy of Cancer 2021
Enhancing clinical and immunological effects of anti-PD-1 with belapectin, a galectin-3 inhibitor
BD Curti, Y Koguchi, RS Leidner, AS Rolig, ER Sturgill, Z Sun, Y Wu, V Rajamanickam, B Bernard, I Hilgart-Martiszus, CB Fountain, G Morris, N Iwamoto, T Shimada, SC Chang, PG Traber, E Zomer, JR Horton, H Shlevin, WL Redmond 		Journal for ImmunoTherapy of Cancer 2021
Interplay of Immunometabolism and Epithelial–Mesenchymal Transition in the Tumor Microenvironment
MY Chou, MH Yang 		International journal of molecular sciences 2021
Phospholipase A2 Drives Tumorigenesis and Cancer Aggressiveness through Its Interaction with Annexin A1
L Vecchi, TG Araújo, FV de Vasconcelos Azevedo, ST Mota, V de Melo Rodrigues Ávila, MA Ribeiro, LR Goulart 		Cells 2021
Advancing to the era of cancer immunotherapy
Y Wang, M Wang, HX Wu, RH Xu 		2021
Bulk and Single-Cell Profiling of Breast Tumors Identifies TREM-1 as a Dominant Immune Suppressive Marker Associated With Poor Outcomes
AK Pullikuth, ED Routh, KD Zimmerman, J Chifman, JW Chou, MH Soike, G Jin, J Su, Q Song, MA Black, C Print, D Bedognetti, M Howard-McNatt, SS ONeill, A Thomas, CD Langefeld, AB Sigalov, Y Lu, LD Miller 		Frontiers in Oncology 2021
Translational Research in Breast Cancer
DY Noh, W Han, M Toi 		Translational Research in Breast Cancer 2021
Myeloid-derived suppressor cells as immunosuppressive regulators and therapeutic targets in cancer
K Li, H Shi, B Zhang, X Ou, Q Ma, Y Chen, P Shu, D Li, Y Wang 		Signal Transduction and Targeted Therapy 2021
Crosstalk between cancer-associated fibroblasts and immune cells in the tumor microenvironment: new findings and future perspectives
X Mao, J Xu, W Wang, C Liang, J Hua, J Liu, B Zhang, Q Meng, X Yu, S Shi 		Molecular Cancer 2021
HDAC inhibition potentiates anti-tumor activity of macrophages and enhances anti-PD-L1-mediated tumor suppression
X Li, X Su, R Liu, Y Pan, J Fang, L Cao, C Feng, Q Shang, Y Chen, C Shao, Y Shi 		Oncogene 2021
Pancreatic Cancer Microenvironment and Cellular Composition: Current Understandings and Therapeutic Approaches
LH Truong, S Pauklin 		Cancers 2021
Calcium/Calmodulin Dependent Protein Kinase Kinase 2 Regulates the Expansion of Tumor-Induced Myeloid-Derived Suppressor Cells
W Huang, Y Liu, A Luz, M Berrong, JN Meyer, Y Zou, E Swann, P Sundaramoorthy, Y Kang, S Jauhari, W Lento, N Chao, L Racioppi 		Frontiers in immunology 2021
CD95/Fas protects triple negative breast cancer from anti-tumor activity of NK cells
AS Qadir, JP Guégan, C Ginestier, A Chaibi, A Bessede, E Charafe-Jauffret, M Macario, V Lavoué, T de la Motte Rouge, C Law, J Vilker, H Wang, E Stroup, MJ Schipma, B Bridgeman, AE Murmann, Z Ji, P Legembre, ME Peter 		iScience 2021
Hypomethylating Agents and Immunotherapy: Therapeutic Synergism in Acute Myeloid Leukemia and Myelodysplastic Syndromes
KK Wong, R Hassan, NS Yaacob 		Frontiers in Oncology 2021
Myeloid-derived suppressor cells in gastrointestinal cancers: A systemic review
M Farshidpour, M Ahmed, S Junna, JL Merchant 		World journal of gastrointestinal oncology 2021
From Good to Bad: The Opposing Effects of PTHrP on Tumor Growth, Dormancy, and Metastasis Throughout Cancer Progression
CM Edwards, RW Johnson 		Frontiers in Oncology 2021
Atovaquone Suppresses Triple-Negative Breast Tumor Growth by Reducing Immune-Suppressive Cells
N Gupta, S Gaikwad, I Kaushik, SE Wright, MM Markiewski, SK Srivastava 		International journal of molecular sciences 2021
Lipid Metabolism in Tumor Immunity
Y Li 		2021
Myeloid Cell Mediated Ilmmune Suppression in Pancreatic Cancer
SB Kemp, MP di Magliano, HC Crawford 		CMGH Cellular and Molecular Gastroenterology and Hepatology 2021
Local Depletion of Immune Checkpoint Ligand CTLA4 Expressing Cells in Tumor Beds Enhances Antitumor Host Immunity
R Okada, T Kato, A Furusawa, F Inagaki, H Wakiyama, PL Choyke, H Kobayashi 		2021
Pharmacological Wnt ligand inhibition overcomes key tumor-mediated resistance pathways to anti-PD-1 immunotherapy
NC DeVito, M Sturdivant, B Thievanthiran, C Xiao, MP Plebanek, AK Salama, GM Beasley, A Holtzhausen, V Novotny-Diermayr, JH Strickler, BA Hanks 		Cell Reports 2021
TGF-β Increases MFGE8 Production in Myeloid-Derived Suppressor Cells to Promote B16F10 Melanoma Metastasis
H Lim, T Yang, W Lee, SG Park 		Biomedicines 2021
Natural Killer Cell Interactions With Myeloid Derived Suppressor Cells in the Tumor Microenvironment and Implications for Cancer Immunotherapy
C Zalfa, S Paust 		Frontiers in immunology 2021
Severe COVID-19 Is Characterized by an Impaired Type I Interferon Response and Elevated Levels of Arginase Producing Granulocytic Myeloid Derived Suppressor Cells
MJ Dean, JB Ochoa, MD Sanchez-Pino, J Zabaleta, J Garai, LD Valle, D Wyczechowska, LB Baiamonte, P Philbrook, R Majumder, RS Heide, L Dunkenberger, RP Thylur, B Nossaman, WM Roberts, AG Chapple, J Wu, C Hicks, J Collins, B Luke, R Johnson, HK Koul, CA Rees, CR Morris, J Garcia-Diaz, AC Ochoa 		Frontiers in immunology 2021
Icaritin Induces Anti-tumor Immune Responses in Hepatocellular Carcinoma by Inhibiting Splenic Myeloid-Derived Suppressor Cell Generation
H Tao, M Liu, Y Wang, S Luo, Y Xu, B Ye, L Zheng, K Meng, L Li 		Frontiers in immunology 2021
Glucosamine Interferes With Myelopoiesis and Enhances the Immunosuppressive Activity of Myeloid-Derived Suppressor Cells
EC Lin, SW Chen, LK Chen, TA Lin, YX Wu, CC Juan, YI Chang 		Frontiers in Nutrition 2021
Realization of Osteolysis, Angiogenesis, Immunosuppression, and Drug Resistance by Extracellular Vesicles: Roles of RNAs and Proteins in Their Cargoes and of Ectonucleotidases of the Immunosuppressive Adenosinergic Noncanonical Pathway in the Bone Marrow Niche of Multiple Myeloma
T Watanabe 		Cancers 2021
Role of Inflammatory Mediators, Macrophages, and Neutrophils in Glioma Maintenance and Progression: Mechanistic Understanding and Potential Therapeutic Applications
AS Basheer, F Abas, I Othman, R Naidu 		Cancers 2021
Runx2 Deficiency in Osteoblasts Promotes Myeloma Resistance to Bortezomib by Increasing TSP-1–Dependent TGFβ1 Activation and Suppressing Immunity in Bone Marrow
C Zhang, X Xu, T Trotter, P Gowda, Y Lu, M Suto, A Javed, J Murphy-Ullrich, J Li, Y Yang 		Molecular cancer therapeutics 2021
Role of Complement in Regulating Inflammation Processes in Renal and Prostate Cancers
GS Netti, R Franzin, A Stasi, F Spadaccino, AD Strologo, B Infante, L Gesualdo, G Castellano, E Ranieri, G Stallone 		Cells 2021
BATF2 prevents glioblastoma multiforme progression by inhibiting recruitment of myeloid-derived suppressor cells
X Zhang, Y Liu, L Dai, G Shi, J Deng, Q Luo, Q Xie, L Cheng, C Li, Y Lin, Q Wang, P Fan, H Zhang, X Su, S Zhang, Y Yang, X Hu, Q Gong, D Yu, L Zheng, H Deng 		Oncogene 2021
The Potential Regulatory Roles of Circular RNAs in Tumor Immunology and Immunotherapy
Z Fang, C Jiang, S Li 		Frontiers in immunology 2021
Immunopathogenesis of Craniotomy Infection and Niche-Specific Immune Responses to Biofilm
SD de Morais, G Kak, JP Menousek, T Kielian 		Frontiers in immunology 2021
Myeloid-derived suppressor cell subtypes differentially influence T-cell function, T-helper subset differentiation, and clinical course in CLL
G Ferrer, B Jung, PY Chiu, R Aslam, F Palacios, AN Mazzarello, S Vergani, D Bagnara, SS Chen, S Yancopoulos, A Xochelli, XJ Yan, JA Burger, JC Barrientos, JE Kolitz, SL Allen, K Stamatopoulos, KR Rai, B Sherry, N Chiorazzi 		Leukemia 2021
Metabolic Remodeling in Glioma Immune Microenvironment: Intercellular Interactions Distinct From Peripheral Tumors
R Qiu, Y Zhong, Q Li, Y Li, H Fan 		Frontiers in Cell and Developmental Biology 2021
Association between cellular immune response and spleen weight in mice with hepatocellular carcinoma
W Jiang, Y Li, S Zhang, G Kong, Z Li 		Oncology Letters 2021
Targeting MDSC for Immune-Checkpoint Blockade in Cancer Immunotherapy: Current Progress and New Prospects
T Li, T Liu, W Zhu, S Xie, Z Zhao, B Feng, H Guo, R Yang 		Clinical Medicine Insights. Oncology 2021
The Stromal and Immune Landscape of Nasopharyngeal Carcinoma and Its Implications for Precision Medicine Targeting the Tumor Microenvironment
L Gong, DL Kwong, W Dai, P Wu, Y Wang, AW Lee, XY Guan 		Frontiers in Oncology 2021
Beyond immunosuppressive effects: dual roles of myeloid-derived suppressor cells in bone-related diseases
Z Ling, C Yang, J Tan, C Dou, Y Chen 		Cellular and Molecular Life Sciences 2021
Sleep Deprivation Disturbs Immune Surveillance and Promotes the Progression of Hepatocellular Carcinoma
J Huang, P Song, K Hang, Z Chen, Z Zhu, Y Zhang, J Xu, J Qin, B Wang, W Qu, Z Huang, C Liang 		Frontiers in immunology 2021
Tumor-Associated Neutrophils in Hepatocellular Carcinoma Pathogenesis, Prognosis, and Therapy
K Arvanitakis, I Mitroulis, G Germanidis 		Cancers 2021
Myeloid cells in COVID-19 microenvironment
G Qin, S Liu, L Yang, W Yu, Y Zhang 		Signal Transduction and Targeted Therapy 2021
Myeloid-Derived Suppressor Cells and Mesenchymal Stem/Stromal Cells in Myeloid Malignancies
S Kapor, JF Santibanez 		Journal of Clinical Medicine 2021
A Tale of Two Viruses: Immunological Insights Into HCV/HIV Coinfection
ST Gobran, P Ancuta, NH Shoukry 		Frontiers in immunology 2021
Difluoromethylornithine (DFMO), an Inhibitor of Polyamine Biosynthesis, and Antioxidant N-Acetylcysteine Potentiate Immune Response in Mice to the Recombinant Hepatitis C Virus NS5B Protein
EI Lesnova, OV Masalova, KY Permyakova, VV Kozlov, TN Nikolaeva, AV Pronin, VT Valuev-Elliston, AV Ivanov, AA Kushch 		International journal of molecular sciences 2021
Myeloid-derived suppressor cells promote lung cancer metastasis by CCL11 to activate ERK and AKT signaling and induce epithelial-mesenchymal transition in tumor cells
S Lin, X Zhang, G Huang, L Cheng, J Lv, D Zheng, S Lin, S Wang, Q Wu, Y Long, B Li, W Wei, P Liu, D Pei, Y Li, Z Wen, S Cui, P Li, X Sun, Y Wu, Y Yao 		Oncogene 2021
Immune Modulation of Metastatic Niche Formation in the Bone
X Cheng, Z Wang 		Frontiers in immunology 2021
Human CD22-Transgenic, Primary Murine Lymphoma Challenges Immunotherapies in Organ-Specific Tumor Microenvironments
F Gsottberger, C Brandl, K Wendland, S Petkovic, C Emmerich, R Erber, C Geppert, A Hartmann, A Mackensen, L Nitschke, F Müller 		International journal of molecular sciences 2021
Treatment with lentiviral vectors encoding shRNA against interleukin 10 modulates the immunosuppressive activity of murine colon carcinoma‑associated myeloid‑derived suppressor cells
N Angergóra, K WęgierekCiura, A Szczygieł, J Mierzejewska, E PajtaszPiasecka, J Rossowska 		Oncology Letters 2021
Single-Cell Omics in Dissecting Immune Microenvironment of Malignant Gliomas—Challenges and Perspectives
B Kaminska, N Ochocka, P Segit 		Cells 2021
Prospective Evaluation of Radiotherapy-Induced Immunologic and Genetic Effects in Colorectal Cancer Oligo-Metastatic Patients with Lung-Limited Disease: The PRELUDE-1 Study
A Ottaiano, A Petito, M Santorsola, V Gigantino, M Capuozzo, D Fontanella, RD Franco, V Borzillo, S Buonopane, V Ravo, E Scipilliti, G Totaro, M Serra, G Ametrano, R Penta, F Tatangelo, G Scognamiglio, AD Mauro, MD Bonito, M Napolitano, S Scala, G Rea, S Santagata, A Lombardi, A Grimaldi, C Caputo, A Crispo, E Celentano, GD Feo, L Circelli, G Savarese, R Ruggiero, F Perri, V Granata, G Botti, M Caraglia, G Nasti, P Muto 		Cancers 2021
PDIA5 is Correlated With Immune Infiltration and Predicts Poor Prognosis in Gliomas
H Zhang, J He, Z Dai, Z Wang, X Liang, F He, Z Xia, S Feng, H Cao, L Zhang, Q Cheng 		Frontiers in immunology 2021
SLC7A2 deficiency promotes hepatocellular carcinoma progression by enhancing recruitment of myeloid-derived suppressors cells
S Xia, J Wu, W Zhou, M Zhang, K Zhao, J Liu, D Tian, J Liao 		Cell Death and Disease 2021
Neutrophil in the Pancreatic Tumor Microenvironment
L Jin, HS Kim, J Shi 		Biomolecules 2021
Inhibition of CCL7 derived from Mo-MDSCs prevents metastatic progression from latency in colorectal cancer
X Ren, J Xiao, W Zhang, F Wang, Y Yan, X Wu, Z Zeng, Y He, W Yang, W Liao, Y Ding, L Liang 		Cell Death and Disease 2021
Intratumoral Injection of a Human Papillomavirus Therapeutic Vaccine-Induced Strong Anti-TC-1-Grafted Tumor Activity in Mice
Y Che, Y Yang, J Suo, C Chen, X Wang 		Cancer management and research 2021
Lymph Node Immune Profiles as Predictive Biomarkers for Immune Checkpoint Inhibitor Response
EF Goode, ET Torres, S Irshad 		Frontiers in Molecular Biosciences 2021
Elevated M-MDSCs in Circulation Are Indicative of Poor Prognosis in Diffuse Large B-Cell Lymphoma Patients
Z Wang, R Jiang, Q Li, H Wang, Q Tao, Z Zhai 		Journal of Clinical Medicine 2021
Identification of an Immune Gene Signature Based on Tumor Microenvironment Characteristics in Colon Adenocarcinoma
Y Chen, J Zhao 		Cell Transplantation 2021
Treatment With Endothelin-A Receptor Antagonist BQ123 Attenuates Acute Inflammation in Mice Through T-Cell-Dependent Polymorphonuclear Myeloid-Derived Suppressor Cell Activation
Z Chen, X Zhang, S Lv, Z Xing, M Shi, X Li, M Chen, S Zuo, Y Tao, G Xiao, J Liu, Y He 		Frontiers in immunology 2021
To inhibit or to boost the ATP/P2RX7 pathway to fight cancer—that is the question
SJ dit Hreich, J Benzaquen, P Hofman, V Vouret-Craviari 		Purinergic Signalling 2021
Repression of MUC1 Promotes Expansion and Suppressive Function of Myeloid-Derived Suppressor Cells in Pancreatic and Breast Cancer Murine Models
M Sahraei, M Bose, JA Sanders, C De, L DasRoy, S Nath, CR Brouwer, P Mukherjee 		International journal of molecular sciences 2021
Critical View of Novel Treatment Strategies for Glioblastoma: Failure and Success of Resistance Mechanisms by Glioblastoma Cells
T Burster, R Traut, Z Yermekkyzy, K Mayer, MA Westhoff, J Bischof, U Knippschild 		Frontiers in Cell and Developmental Biology 2021
Myeloid cell subsets that express latency-associated peptide promote cancer growth by modulating T cells
G Gabriely, D Ma, S Siddiqui, L Sun, NP Skillin, H Abou-El-Hassan, TG Moreira, D Donnelly, AP da Cunha, M Fujiwara, LR Walton, A Patel, R Krishnan, SS Levine, BC Healy, RM Rezende, G Murugaiyan, HL Weiner 		iScience 2021
Dual Targeting of Multiple Myeloma Stem Cells and Myeloid-Derived Suppressor Cells for Treatment of Chemotherapy-Resistant Multiple Myeloma
FM Uckun 		Frontiers in Oncology 2021
Targeting Myeloid-Derived Suppressor Cells to Enhance the Antitumor Efficacy of Immune Checkpoint Blockade Therapy
X Li, J Zhong, X Deng, X Guo, Y Lu, J Lin, X Huang, C Wang 		Frontiers in immunology 2021
Immunotherapy Resistance in Glioblastoma
EJ Wang, JS Chen, S Jain, RA Morshed, AF Haddad, S Gill, AS Beniwal, MK Aghi 		Frontiers in Genetics 2021
Current Advances in Immunotherapy for Glioblastoma Multiforme and Future Prospects.
Chowdhury S, Bappy MH, Clocchiatti-Tuozzo S, Cheeti S, Chowdhury S, Patel V 		Cureus 2021
Polymorphonuclear myeloid-derived suppressor cells impair the anti-tumor efficacy of GD2.CAR T-cells in patients with neuroblastoma
Tumino N, Weber G, Besi F, Del Bufalo F, Bertaina V, Paci P, Quatrini L, Antonucci L, Sinibaldi M, Quintarelli C, Maggi E, De Angelis B, Locatelli F, Moretta L, Vacca P, Caruana I 		Journal of Hematology & Oncology 2021
Early Myeloid Derived Suppressor Cells (eMDSCs) Are Associated With High Donor Myeloid Chimerism Following Haploidentical HSCT for Sickle Cell Disease
Bhat DK, Olkhanud PB, Gangaplara A, Seifuddin F, Pirooznia M, Biancotto A, Fantoni G, Pittman C, Francis B, Dagur PK, Saxena A, McCoy JP, Pfeiffer RM, Fitzhugh CD 		Frontiers in immunology 2021
Hypoxic tumor-derived exosomal circular RNA SETDB1 promotes invasive growth and EMT via the miR-7/Sp1 axis in lung adenocarcinoma.
Xu L, Liao WL, Lu QJ, Zhang P, Zhu J, Jiang GN 		2021
LOX-1 and cancer: an indissoluble liaison
Murdocca M, De Masi C, Pucci S, Mango R, Novelli G, Di Natale C, Sangiuolo F 		Cancer Gene Therapy 2021
Immune Dysregulation and Recurring Mutations in Myelodysplastic Syndromes Pathogenesis.
Matos A, Magalhães SMM, Rauh MJ 		Advances in experimental medicine and biology 2021
Biohybrid Nanosystems for Cancer Treatment: Merging the Best of Two Worlds.
Fontana F, Bartolo R, Santos HA 		Advances in experimental medicine and biology 2021
IL-6 Promotes the Proliferation and Immunosuppressive Function of Myeloid-Derived Suppressor Cells via the MAPK Signaling Pathway in Bladder Cancer
Zheng Z, Zheng X, Zhu Y, Yao Z, Zhao W, Zhu Y, Sun F, Mu X, Wang Y, He W, Liu Z, Wu K, Zheng J 		BioMed Research International 2021
TGF-β orchestrates the phenotype and function of monocytic myeloid-derived suppressor cells in colorectal cancer
Gneo L, Rizkalla N, Hejmadi R, Mussai F, de Santo C, Middleton G 		Cancer Immunology, Immunotherapy 2021
CD123-Directed Bispecific Antibodies for Targeting MDS Clones and Immunosuppressive Myeloid-Derived Suppressor Cells (MDSC) in High-Risk Adult MDS Patients
Uckun FM, Watts J 		2021
Revisiting the outstanding questions in cancer nanomedicine with a future outlook.
Sudheesh MS, Pavithran K, M S 		2021
How metabolism bridles cytotoxic CD8+ T cells through epigenetic modifications
Van Acker HH, Ma S, Scolaro T, Kaech SM, Mazzone M 		Trends in Immunology 2021
Nitrogen-Doped Carbon Nanotube Cups for Cancer Therapy
Burkert SC, He X, Shurin GV, Nefedova Y, Kagan VE, Shurin MR, Star A 		2021
A Tumor-intrinsic PD-L1-NLRP3 Inflammasome Signaling Pathway Drives Resistance to Anti-PD-1 Immunotherapy
Balamayooran Theivanthiran, Kathy S. Evans, Nicholas C. DeVito, Michael P. Plebanek, Michael Sturdivant, Lucas P. Wachsmuth, April K.S. Salama, Yubin Kang, David Hsu, Justin M. Balko, Douglas B. Johnson, Mark Starr, Andrew B. Nixon, Alisha Holtzhausen, Brent A. Hanks 		Journal of Clinical Investigation 2020
Activation of STAT3 is a key event in TLR4 signaling-mediated melanoma progression
XQ Fu, B Liu, YP Wang, JK Li, PL Zhu, T Li, KW Tse, JY Chou, CL Yin, JX Bai, YX Liu, YJ Chen, ZL Yu 		Cell Death and Disease 2020
Contribution of Macrophages and T Cells in Skeletal Metastasis
V Mendoza-Reinoso, LK McCauley, PG Fournier 		Cancers 2020
Application of Anti-Inflammatory Agents in Prostate Cancer
K Hatano, K Fujita, N Nonomura 		Journal of Clinical Medicine 2020
Myeloid-derived suppressor cells impede T cell functionality and promote Th17 differentiation in oral squamous cell carcinoma
AA Dar, RS Patil, TN Pradhan, DA Chaukar, AK DCruz, SV Chiplunkar 		Cancer Immunology, Immunotherapy 2020
Unleashing Natural Killer Cells in the Tumor Microenvironment–The Next Generation of Immunotherapy?
A Ben-Shmuel, G Biber, M Barda-Saad 		Frontiers in immunology 2020
Aptamers against mouse and human tumor-infiltrating myeloid cells as reagents for targeted chemotherapy
AD Fuente, S Zilio, J Caroli, DV Simaeys, EM Mazza, TA Ince, V Bronte, S Bicciato, DT Weed, P Serafini 		Science Translational Medicine 2020
Hypoxia-inducible factor 1 alpha limits dendritic cell stimulation of CD8 T cell immunity
CW Tran, MJ Gold, C Garcia-Batres, K Tai, AR Elford, ME Himmel, AJ Elia, PS Ohashi, J Karhausen 		PloS one 2020
Myeloid Cell Modulation by Tumor-Derived Extracellular Vesicles
I Arkhypov, S Lasser, V Petrova, R Weber, C Groth, J Utikal, P Altevogt, V Umansky 		International journal of molecular sciences 2020
CCL2/CCR2 signaling in cancer pathogenesis
Q Hao, JV Vadgama, P Wang 		Cell Communication and Signaling 2020
Friend or Foe? Recent Strategies to Target Myeloid Cells in Cancer
M Chaib, SC Chauhan, L Makowski 		Frontiers in Cell and Developmental Biology 2020
Microbiome, bile acids, and obesity: How microbially modified metabolites shape anti‐tumor immunity
LM Sipe, M Chaib, AK Pingili, JF Pierre, L Makowski 		Immunological Reviews 2020
Mechanisms of Cancer Resistance to Immunotherapy
R Bai, N Chen, L Li, N Du, L Bai, Z Lv, H Tian, J Cui 		Frontiers in Oncology 2020
Tumor immune microenvironment in head and neck cancers
SM Chen, AL Krinsky, RA Woolaver, X Wang, Z Chen, JH Wang 		Molecular Carcinogenesis 2020
MicroRNAs and lncRNAs—A New Layer of Myeloid-Derived Suppressor Cells Regulation
E Safarzadeh, Z Asadzadeh, S Safaei, A Hatefi, A Derakhshani, F Giovannelli, O Brunetti, N Silvestris, B Baradaran 		Frontiers in immunology 2020
Modulation of tumor microenvironment for immunotherapy: focus on nanomaterial-based strategies
Y Liu, J Guo, L Huang 		Theranostics 2020
Tumor Microenvironments in Organs: From the Brain to the Skin – Part B
A Birbrair 		2020
CAR-T Cells Hit the Tumor Microenvironment: Strategies to Overcome Tumor Escape
A Rodriguez-Garcia, A Palazon, E Noguera-Ortega, DJ Powell, S Guedan 		Frontiers in immunology 2020
Cancer and HIV-1 Infection: Patterns of Chronic Antigen Exposure
S Vigano, S Bobisse, G Coukos, M Perreau, A Harari 		Frontiers in immunology 2020
Strategies to Improve Chimeric Antigen Receptor Therapies for Neuroblastoma
P Sawaisorn, K Atjanasuppat, U Anurathapan, S Chutipongtanate, S Hongeng 		Human vaccines 2020
c-Rel is a myeloid checkpoint for cancer immunotherapy
T Li, X Li, A Zamani, W Wang, CN Lee, M Li, G Luo, E Eiler, H Sun, S Ghosh, J Jin, R Murali, Q Ruan, W Shi, YH Chen 		2020
Reprogramming immunosuppressive myeloid cells facilitates immunotherapy for colorectal cancer
W Lu, W Yu, J He, W Liu, J Yang, X Lin, Y Zhang, X Wang, W Jiang, J Luo, Q Zhang, H Yang, S Peng, Z Yi, S Ren, J Chen, S Siwko, R Nussinov, F Cheng, H Zhang, M Liu 		EMBO Molecular Medicine 2020
Myeloid - derived suppressor cells in Type 1 diabetes are an expanded population exhibiting diverse T-cell suppressor mechanisms
A Grohová, K Dáňová, I Adkins, Z Šumník, L Petruželková, B Obermannová, S Koloušková, R Špíšek, L Palová-Jelínková, V Taneja 		PloS one 2020
Lessons from Hippocrates: Time to Change the Cancer Paradigm
CM Galmarini 		International Journal of Chronic Diseases 2020
Anti-Cancer Immunotherapies Targeting Telomerase
S Negrini, RD Palma, G Filaci 		Cancers 2020
Response to radiotherapy in pancreatic ductal adenocarcinoma is enhanced by inhibition of myeloid-derived suppressor cells using STAT3 anti-sense oligonucleotide
AJ Oweida, AC Mueller, M Piper, D Milner, BV Court, S Bhatia, A Phan, T Bickett, K Jordan, T Proia, R Schulick, WA Messersmith, MD Chiaro, E Clambey, MJ Gough, J Williams, K Hansen, K Goodman, SD Karam 		Cancer Immunology, Immunotherapy 2020
Immunobiology and immunotherapy of HCC: spotlight on innate and innate-like immune cells
B Ruf, B Heinrich, TF Greten 		Cellular and Molecular Immunology 2020
Myeloid-Derived Suppressor Cells as a Therapeutic Target for Cancer
AM Law, F Valdes-Mora, D Gallego-Ortega 		Cells 2020
Explicating the Pivotal Pathogenic, Diagnostic, and Therapeutic Biomarker Potentials of Myeloid-Derived Suppressor Cells in Glioblastoma
SA Richard, WJ Tu 		Disease Markers 2020
Myeloid-Derived Suppressor Cells: A New and Pivotal Player in Colorectal Cancer Progression
K Yin, X Xia, K Rui, T Wang, S Wang 		Frontiers in Oncology 2020
Neutrophil Elastase Facilitates Tumor Cell Intravasation and Early Metastatic Events
E Deryugina, A Carré, V Ardi, T Muramatsu, J Schmidt, C Pham, JP Quigley 		iScience 2020
Immune suppression in gliomas
MM Grabowski, EW Sankey, KJ Ryan, P Chongsathidkiet, SJ Lorrey, DS Wilkinson, PE Fecci 		Journal of Neuro-Oncology 2020
A pan-cancer blueprint of the heterogeneous tumor microenvironment revealed by single-cell profiling
J Qian, S Olbrecht, B Boeckx, H Vos, D Laoui, E Etlioglu, E Wauters, V Pomella, S Verbandt, P Busschaert, A Bassez, A Franken, MV Bempt, J Xiong, B Weynand, Y van Herck, A Antoranz, FM Bosisio, B Thienpont, G Floris, I Vergote, A Smeets, S Tejpar, D Lambrechts 		Cell Research 2020
Hyperprogression: A novel response pattern under immunotherapy
X Han, A Alu, Y Xiao, Y Wei, X Wei 		Clinical and Translational Medicine 2020
Brief review on the roles of neutrophils in cancer development
W Long, J Chen, C Gao, Z Lin, X Xie, H Dai 		Journal of leukocyte biology 2020
Emerging Prospects for Nanoparticle-Enabled Cancer Immunotherapy
MA Buabeid, ES Arafa, G Murtaza 		Journal of Immunology Research 2020
Loss of myeloid‐specific lamin A/C drives lung metastasis through Gfi‐1 and C/EBPε‐mediated granulocytic differentiation
H Ishii, WY Park, J So, S Kuhn, VN Koparde, Y Pang, TF Greten, MC Hollander, L Yang 		Molecular Carcinogenesis 2020
Mycobacterium tuberculosis and myeloid-derived suppressor cells: Insights into caveolin rich lipid rafts
LA Kotzé, C Young, VN Leukes, V John, Z Fang, G Walzl, MB Lutz, N du Plessis 		EBioMedicine 2020
Immunotherapy for advanced thyroid cancers — rationale, current advances and future strategies
JD French 		Nature Reviews Endocrinology 2020
TET family dioxygenases and the TET activator vitamin C in immune responses and cancer
X Yue, A Rao 		Blood 2020
Design and Implementation of NK Cell-Based Immunotherapy to Overcome the Solid Tumor Microenvironment
I Navin, MT Lam, R Parihar 		Cancers 2020
Long Non-coding RNAs: Emerging Roles in the Immunosuppressive Tumor Microenvironment
Y Luo, J Yang, J Yu, X Liu, C Yu, J Hu, H Shi, X Ma 		Frontiers in Oncology 2020
Bone metastases: a comprehensive review of the literature
F Migliorini, N Maffulli, A Trivellas, J Eschweiler, M Tingart, A Driessen 		Molecular Biology Reports 2020
Immune‐checkpoint molecules on regulatory T‐cells as a potential therapeutic target in head and neck squamous cell cancers
S Suzuki, T Ogawa, R Sano, T Takahara, D Inukai, S Akira, H Tsuchida, K Yoshikawa, R Ueda, T Tsuzuki 		Cancer Science 2020
Immunomodulatory Effects of Radiotherapy
S Kumari, S Mukherjee, D Sinha, S Abdisalaam, S Krishnan, A Asaithamby 		International journal of molecular sciences 2020
Nanomedicines modulating tumor immunosuppressive cells to enhance cancer immunotherapy
Y Zhu, X Yu, SD Thamphiwatana, Y Zheng, Z Pang 		Acta pharmaceutica Sinica. B 2020
Transcriptomic Analyses of Myeloid-Derived Suppressor Cell Subsets in the Circulation of Colorectal Cancer Patients
VS Nair, R Saleh, SM Toor, NM Alajez, E Elkord 		Frontiers in Oncology 2020
Myeloid‐derived suppressor cells promote epithelial ovarian cancer cell stemness by inducing the CSF2/p‐STAT3 signalling pathway
X Li, J Wang, W Wu, H Gao, N Liu, G Zhan, L Li, L Han, X Guo 		The FEBS journal 2020
Differential regulation of breast cancer bone metastasis by PARP1 and PARP2
H Zuo, D Yang, Q Yang, H Tang, YX Fu, Y Wan 		Nature Communications 2020
TET2 promotes anti-tumor immunity by governing G-MDSCs and CD8 + T-cell numbers
S Li, J Feng, F Wu, J Cai, X Zhang, H Wang, IS Fetahu, I Iwanicki, D Ma, T Hu, H Liu, B Wang, G Shi, L Tan, YG Shi 		EMBO reports 2020
Immunoregulatory Cells in Myasthenia Gravis
Y Wu, J Luo, OA Garden 		Frontiers in neurology 2020
Effect of Octreotide Long-Acting Release on Tregs and MDSC Cells in Neuroendocrine Tumour Patients: A Pivotal Prospective Study
C von Arx, G Rea, M Napolitano, A Ottaiano, F Tatangelo, F Izzo, A Petrillo, O Clemente, AD Sarno, G Botti, S Scala, S Tafuto 		Cancers 2020
Prostaglandin E Receptor 4 Antagonist in Cancer Immunotherapy: Mechanisms of Action
Y Take, S Koizumi, A Nagahisa 		Frontiers in immunology 2020
High M-MDSC Percentage as a Negative Prognostic Factor in Chronic Lymphocytic Leukaemia
M Zarobkiewicz, W Kowalska, S Chocholska, W Tomczak, A Szymańska, I Morawska, A Wojciechowska, A Bojarska-Junak 		Cancers 2020
Resistance Mechanisms of Anti-PD1/PDL1 Therapy in Solid Tumors
Q Lei, D Wang, K Sun, L Wang, Y Zhang 		Frontiers in Cell and Developmental Biology 2020
Peripheral natural killer cells and myeloid-derived suppressor cells correlate with anti-PD-1 responses in non-small cell lung cancer
JI Youn, SM Park, S Park, G Kim, HJ Lee, J Son, MH Hong, A Ghaderpour, B Baik, J Islam, JW Choi, EY Lee, HR Kim, SU Seo, S Paik, HI Yoon, I Jung, CF Xin, HT Jin, BC Cho, SY Seong, SJ Ha, HR Kim 		Scientific Reports 2020
Anti-angiogenic Agents in Combination With Immune Checkpoint Inhibitors: A Promising Strategy for Cancer Treatment
Y Song, Y Fu, Q Xie, B Zhu, J Wang, B Zhang 		Frontiers in immunology 2020
Impact of inflammation and immunotherapy in renal cell carcinoma (Review)
J Shi, K Wang, Z Xiong, C Yuan, C Wang, Q Cao, H Yu, X Meng, K Xie, Z Cheng, H Yang, K Chen, X Zhang 		Oncology Letters 2020
Sunitinib Treatment-elicited Distinct Tumor Microenvironment Dramatically Compensated the Reduction of Myeloid-derived Suppressor Cells
FU SY, WANG CC, CHEN FH, YU CF, HONG JH, CHIANG CS 		In vivo (Athens, Greece) 2020
Malignant Pleural Mesothelioma: Genetic and Microenviromental Heterogeneity as an Unexpected Reading Frame and Therapeutic Challenge
Abbott DM, Bortolotto C, Benvenuti S, Lancia A, Filippi AR, Stella GM 		Cancers 2020
Effects of dexmedetomidine on immune response in patients undergoing radical and reconstructive surgery for oral cancer
Huang L, Qin C, Wang L, Zhang T, Li J 		Oncology Letters 2020
Oncolytic virotherapy: new weapon for breast cancer treatment
Martini V, D\u2019Avanzo F, Maggiora PM, Varughese FM, Sica A, Gennari A 		ecancermedicalscience 2020
Transcriptomic profiling disclosed the role of DNA methylation and histone modifications in tumor-infiltrating myeloid-derived suppressor cell subsets in colorectal cancer.
Sasidharan Nair V, Saleh R, Toor SM, Taha RZ, Ahmed AA, Kurer MA, Murshed K, Alajez NM, Abu Nada M, Elkord E 		Clinical Epigenetics 2020
Consistency Analysis of Programmed Death-Ligand 1 Expression between Primary and Metastatic Non-Small Cell Lung Cancer: A Retrospective Study.
Luo L, Luo X, Chen W, Liang C, Yao S, Huang W, Liu C, Ge Y, Lin X, Li Z 		Journal of Cancer 2020
Myeloid-derived suppressor cells infiltration in non-small-cell lung cancer tumor and MAGE-A4 and NY-ESO-1 expression
Hou Z, Liang X, Wang X, Zhou Z, Shi G 		Oncology Letters 2020
Fundamentals to clinical application of nanoparticles in cancer immunotherapy and radiotherapy
Selvaraja VK, Gudipudi DK 		ecancermedicalscience 2020
Interleukin-35 promotes progression of prostate cancer and inhibits anti-tumour immunity
Zhu J, Wang Y, Li D, Zhang H, Guo Z, Yang X 		Cancer Cell International 2020
Identification of an extracellular vesicle-related gene signature in the prediction of pancreatic cancer clinical prognosis.
Xu D, Wang Y, Zhou K, Wu J, Zhang Z, Zhang J, Yu Z, Liu L, Liu X, Li B, Zheng J 		Bioscience Reports 2020
Palliative Radiofrequency Ablation Accelerates the Residual Tumor Progression Through Increasing Tumor-Infiltrating MDSCs and Reducing T-Cell-Mediated Anti-Tumor Immune Responses in Animal Model
Wu H, Li SS, Zhou M, Jiang AN, He Y, Wang S, Yang W, Liu H 		Frontiers in Oncology 2020
Mannose-Modified Liposome Co-Delivery of Human Papillomavirus Type 16 E7 Peptide and CpG Oligodeoxynucleotide Adjuvant Enhances Antitumor Activity Against Established Large TC-1 Grafted Tumors in Mice.
Zhao Y, Wang H, Yang Y, Jia W, Su T, Che Y, Feng Y, Yuan X, Wang X 		International Journal of Nanomedicine 2020
Stress‐induced premature senescence activated by the SENEX gene mediates apoptosis resistance of diffuse large B‐cell lymphoma via promoting immunosuppressive cells and cytokines
Wang J, Tao Q, Pan Y, Wanyan Z, Zhu F, Xu X, Wang H, Yi L, Zhou M, Zhai Z 		Immunity, Inflammation and Disease 2020
PD-L1过表达对CLL-1 CAR-T细胞抗急性髓系白血病作用的影响
2020
Importance of myeloid derived suppressor cells in cancer from a biomarker perspective
Kalathil SG, Thanavala Y 		Cellular Immunology 2020
Ganoderma lucidum polysaccharide (GLP) enhances antitumor immune response by regulating differentiation and inhibition of MDSCs via a CARD9-NF-κB-IDO pathway.
Wang Y, Fan X, Wu X 		Bioscience Reports 2020
Neutrophil Elastase from Myeloid Cells Promotes TSC2-null Tumor Growth
Taya M, Garcia-Hernandez MD, Rangel-Moreno J, Minor B, Gibbons E, Hammes SR 		Endocrine Related Cancer 2020
Induction of systemic immune responses and reversion of immunosuppression in the tumor microenvironment by a therapeutic vaccine for cervical cancer.
Che Y, Yang Y, Suo J, An Y, Wang X 		Cancer Immunology, Immunotherapy 2020
NK1R antagonist decreases inflammation and metastasis of breast carcinoma cells metastasized to liver but not to brain; phenotype-dependent therapeutic and toxic consequences.
Nizam E, Köksoy S, Erin N 		Cancer Immunology, Immunotherapy 2020
Tofacitinib enhances delivery of antibody-based therapeutics to tumor cells through modulation of inflammatory cells
Nathan Simon, Antonella Antignani, Stephen M. Hewitt, Massimo Gadina, Christine Alewine, David Fitzgerald 		JCI Insight 2019
Relief of tumor hypoxia unleashes the tumoricidal potential of neutrophils
Karim Mahiddine, Adam Blaisdell, Stephany Ma, Amandine Créquer-Grandhomme, Clifford A. Lowell, Adrian Erlebacher 		Journal of Clinical Investigation 2019
NK cells expressing a chimeric activating receptor eliminate MDSCs and rescue impaired CAR-T cell activity against solid tumors
R Parihar, CH Rivas, M Huynh, B Omer, N Lapteva, LS Metelitsa, S Gottschalk, CM Rooney 		Cancer immunology research 2019
Broadening the Impact of Immunotherapy to Pancreatic Cancer: Challenges and Opportunities
VP Balachandran, GL Beatty, SK Dougan 		Gastroenterology 2019
Drug Delivery for Cancer Immunotherapy and Vaccines
CJ Batty, P Tiet, EM Bachelder, KM Ainslie 		2019
Plasmodium infection inhibits the expansion and activation of MDSCs and Tregs in the tumor microenvironment in a murine Lewis lung cancer model
D Adah, Y Yang, Q Liu, K Gadidasu, Z Tao, S Yu, L Dai, X Li, S Zhao, L Qin, L Qin, X Chen 		Cell Communication and Signaling 2019
Strategies to Interfere with Tumor Metabolism through the Interplay of Innate and Adaptive Immunity
J Mora, C Mertens, JK Meier, DC Fuhrmann, B Brüne, M Jung 		Cells 2019
Cysteine Cathepsins in Tumor-Associated Immune Cells
T Jakoš, A Pišlar, A Jewett, J Kos 		Frontiers in immunology 2019
Exosomes Produced by Mesenchymal Stem Cells Drive Differentiation of Myeloid Cells into Immunosuppressive M2-Polarized Macrophages in Breast Cancer
S Biswas, G Mandal, SR Chowdhury, S Purohit, KK Payne, C Anadon, A Gupta, P Swanson, X Yu, JR Conejo-Garcia, A Bhattacharyya 		Journal of immunology (Baltimore, Md. : 1950) 2019
Immune and Inflammatory Cells in Thyroid Cancer Microenvironment
Ferrari, Fallahi, Galdiero, Ruffilli, Elia, Ragusa, Paparo, Patrizio, Mazzi, Varricchi, Marone, Antonelli 		International journal of molecular sciences 2019
Trabectedin Reduces Skeletal Prostate Cancer Tumor Size in Association with Effects on M2 Macrophages and Efferocytosis
JD Jones, BP Sinder, D Paige, FN Soki, AJ Koh, S Thiele, Y Shiozawa, LC Hofbauer, S Daignault, H Roca, LK McCauley 		Neoplasia (New York, N.Y.) 2019
The Role of TRAIL/DRs in the Modulation of Immune Cells and Responses
D Sag, ZO Ayyildiz, S Gunalp, G Wingender 		Cancers 2019
Estrogen promotes multiple myeloma through enhancing the immunosuppressive activity of MDSC
M Ozerova, Y Nefedova 		Leukemia & Lymphoma 2019
Functional Diversity of Myeloid-Derived Suppressor Cells: The Multitasking Hydra of Cancer
A Jayakumar, AL Bothwell 		Journal of immunology (Baltimore, Md. : 1950) 2019

Application Of Adoptive Immunotherapy In Ovarian Cancer
S Yang, X Yin, Y Yue, S Wang 		OncoTargets and therapy 2019
Increased CD14+HLA-DR−/low Myeloid-Derived Suppressor Cells Correlate With Disease Severity in Systemic Lupus Erythematosus Patients in an iNOS-Dependent Manner
Z Wang, F Zhu, J Wang, Q Tao, X Xu, H Wang, S Xiong, Y Wang, Z Zhai 		Frontiers in immunology 2019
Different role of circulating myeloid-derived suppressor cells in patients with multiple myeloma undergoing autologous stem cell transplantation
SE Lee, JY Lim, TW Kim, DB Ryu, SS Park, YW Jeon, JH Yoon, BS Cho, KS Eom, YJ Kim, HJ Kim, S Lee, SG Cho, DW Kim, JW Lee, CK Min 		Journal for ImmunoTherapy of Cancer 2019
Myeloid Derived Suppressor Cells Interactions With Natural Killer Cells and Pro-angiogenic Activities: Roles in Tumor Progression
A Bruno, L Mortara, D Baci, DM Noonan, A Albini 		Frontiers in immunology 2019
Tumor-Infiltrating Immunosuppressive Cells in Cancer-Cell Plasticity, Tumor Progression and Therapy Response
L Lorenzo-Sanz, P Muñoz 		Cancer Microenvironment 2019
Phenotypic and transcriptomic characterization of canine myeloid-derived suppressor cells
MR Goulart, SI Hlavaty, YM Chang, G Polton, A Stell, J Perry, Y Wu, E Sharma, J Broxholme, AC Lee, B Szladovits, M Turmaine, J Gribben, D Xia, OA Garden 		Scientific Reports 2019
Cancer cells induce immune escape via glycocalyx changes controlled by the telomeric protein TRF 2
J CherfilsVicini, C Iltis, L Cervera, S Pisano, O Croce, N Sadouni, B Győrffy, R Collet, VM Renault, M ReyMillet, C Leonetti, P Zizza, F Allain, F Ghiringhelli, N Soubeiran, M Shkreli, E Vivier, A Biroccio, E Gilson 		The EMBO Journal 2019
CXCR2 expression on granulocyte and macrophage progenitors under tumor conditions contributes to mo-MDSC generation via SAP18/ERK/STAT3
X Han, H Shi, Y Sun, C Shang, T Luan, D Wang, X Zeng, X Ba 		Cell Death and Disease 2019
The Role of Checkpoint Inhibitors in Glioblastoma
K Desai, A Hubben, M Ahluwalia 		Targeted Oncology 2019
Primary tumor-induced immunity eradicates disseminated tumor cells in syngeneic mouse model
R Piranlioglu, EM Lee, M Ouzounova, RJ Bollag, AH Vinyard, AS Arbab, D Marasco, M Guzel, JK Cowell, M Thangaraju, A Chadli, KA Hassan, MS Wicha, E Celis, H Korkaya 		Nature Communications 2019
KRAS-IRF2 Axis Drives Immune Suppression and Immune Therapy Resistance in Colorectal Cancer
W Liao, MJ Overman, AT Boutin, X Shang, D Zhao, P Dey, J Li, G Wang, Z Lan, J Li, M Tang, S Jiang, X Ma, P Chen, R Katkhuda, K Korphaisarn, D Chakravarti, A Chang, DJ Spring, Q Chang, J Zhang, DM Maru, DY Maeda, JA Zebala, S Kopetz, YA Wang, RA DePinho 		Cancer Cell 2019
Lipid Metabolic Pathways Confer the Immunosuppressive Function of Myeloid-Derived Suppressor Cells in Tumor
D Yan, AO Adeshakin, M Xu, LO Afolabi, G Zhang, YH Chen, X Wan 		Frontiers in immunology 2019
Allies or Enemies—The Multifaceted Role of Myeloid Cells in the Tumor Microenvironment
L Haas, AC Obenauf 		Frontiers in immunology 2019
Clinical Relevance and Immunosuppressive Pattern of Circulating and Infiltrating Subsets of Myeloid-Derived Suppressor Cells (MDSCs) in Epithelial Ovarian Cancer
K Okła, A Czerwonka, A Wawruszak, M Bobiński, M Bilska, R Tarkowski, W Bednarek, I Wertel, J Kotarski 		Frontiers in immunology 2019
Targeting innate sensing in the tumor microenvironment to improve immunotherapy
Z Liu, C Han, YX Fu 		Cellular and Molecular Immunology 2019
Increased intratumoral mast cells foster immune suppression and gastric cancer progression through TNF-α-PD-L1 pathway
Y Lv, Y Zhao, X Wang, N Chen, F Mao, Y Teng, T Wang, L Peng, J Zhang, P Cheng, Y Liu, H Kong, W Chen, C Hao, B Han, Q Ma, Q Zou, J Chen, Y Zhuang 		Journal for ImmunoTherapy of Cancer 2019
The immunomodulatory potential of natural compounds in tumor-bearing mice and humans
P Pan, YW Huang, K Oshima, M Yearsley, J Zhang, M Arnold, J Yu, LS Wang 		Critical Reviews in Food Science and Nutrition 2019
Diverging inflammasome signals in tumorigenesis and potential targeting
R Karki, TD Kanneganti 		Nature Reviews Cancer 2019
Temporal and spatial profile of polymorphonuclear myeloid-derived suppressor cells (PMN-MDSCs) in ischemic stroke in mice
T Kawano, M Shimamura, H Nakagami, H Kanki, T Sasaki, H Mochizuki, M Mogi 		PloS one 2019
Tumor derived EDIL3 modulates the expansion and osteoclastogenesis of myeloid derived suppressor cells in murine breast cancer model
Z Kun, G Xin, W Tao, Z Chenglong, W Dongsheng, T Liang, L Tielong, X Jianru 		Journal of Bone Oncology 2019
GNAI1 and GNAI3 Reduce Colitis-Associated Tumorigenesis in Mice by Blocking IL6 Signaling and Down-regulating Expression of GNAI2
ZW Li, B Sun, T Gong, S Guo, J Zhang, J Wang, A Sugawara, M Jiang, J Yan, A Gurary, X Zheng, B Gao, SY Xiao, W Chen, C Ma, C Farrar, C Zhu, OT Chan, C Xin, A Winnicki, J Winnicki, M Tang, R Park, M Winnicki, K Diener, Z Wang, Q Liu, CH Chu, ZL Arter, P Yue, L Alpert, GS Hui, P Fei, J Turkson, W Yang, G Wu, A Tao, JW Ramos, S Moisyadi, RF Holcombe, W Jia, L Birnbaumer, X Zhou, WM Chu 		Gastroenterology 2019
MicroRNAs as Molecular Switches in Macrophage Activation
G Curtale, M Rubino, M Locati 		Frontiers in immunology 2019
PMN-MDSCs Enhance CTC Metastatic Properties through Reciprocal Interactions via ROS/Notch/Nodal Signaling
ML Sprouse, T Welte, D Boral, HN Liu, W Yin, M Vishnoi, D Goswami-Sewell, L Li, G Pei, P Jia, IC Glitza-Oliva, D Marchetti 		International journal of molecular sciences 2019
Enhancing Dendritic Cell Therapy in Solid Tumors with Immunomodulating Conventional Treatment
RA Belderbos, JG Aerts, H Vroman 		Molecular Therapy — Oncolytics 2019
Epigenetic Suppression of SERPINB1 Promotes Inflammation-Mediated Prostate Cancer Progression
I Lerman, X Ma, C Seger, A Maolake, M de la Luz Garcia-Hernandez, J Rangel-Moreno, J Ackerman, KL Nastiuk, M Susiarjo, SR Hammes 		Molecular cancer research : MCR 2019
Perforin and Granzyme B Expressed by Murine Myeloid-Derived Suppressor Cells: A Study on Their Role in Outgrowth of Cancer Cells
I Dufait, J Pardo, D Escors, YD Vlaeminck, H Jiang, M Keyaerts, MD Ridder, K Breckpot 		Cancers 2019
A Call for Epidemiological Research on Myeloid-Derived Suppressor Cells in Ovarian Cancer: A Review of the Existing Immunological Evidence and Suggestions for Moving Forward
AE Stenzel, SI Abrams, KB Moysich 		Frontiers in immunology 2019
Apelin inhibition prevents resistance and metastasis associated with anti‐angiogenic therapy
I Uribesalgo, D Hoffmann, Y Zhang, A Kavirayani, J Lazovic, J Berta, M Novatchkova, TP Pai, RA Wimmer, V László, D Schramek, R Karim, L Tortola, S Deswal, L Haas, J Zuber, M Szűcs, K Kuba, B Dome, Y Cao, BJ Haubner, JM Penninger 		EMBO Molecular Medicine 2019
ATR Inhibition Potentiates the Radiation-induced Inflammatory Tumor Microenvironment
MT Dillon, KF Bergerhoff, M Pedersen, H Whittock, E Crespo-Rodriguez, EC Patin, A Pearson, HG Smith, JT Paget, RR Patel, S Foo, G Bozhanova, C Ragulan, E Fontana, K Desai, AC Wilkins, A Sadanandam, A Melcher, M McLaughlin, KJ Harrington 		Clinical cancer research 2019
Syringeable immunotherapeutic nanogel reshapes tumor microenvironment and prevents tumor metastasis and recurrence
C Song, H Phuengkham, YS Kim, VV Dinh, I Lee, IW Shin, HS Shin, SM Jin, SH Um, H Lee, KS Hong, SM Jin, E Lee, TH Kang, YM Park, YT Lim 		Nature Communications 2019
Is There a Place for Immunotherapy for Metastatic Microsatellite Stable Colorectal Cancer?
F Ghiringhelli, JD Fumet 		Frontiers in immunology 2019
Multifunctional Nanoregulator Reshapes Immune Microenvironment and Enhances Immune Memory for Tumor Immunotherapy
M Yu, X Duan, Y Cai, F Zhang, S Jiang, S Han, J Shen, X Shuai 		Advanced Science 2019
Myeloid cell–synthesized coagulation factor X dampens antitumor immunity
C Graf, P Wilgenbus, S Pagel, J Pott, F Marini, S Reyda, M Kitano, S Macher-Göppinger, H Weiler, W Ruf 		Science Immunology 2019
The prognostic value of myeloid derived suppressor cell level in hepatocellular carcinoma: A systematic review and meta-analysis
X Zhang, X Fu, T Li, H Yan, JC Hsieh 		PloS one 2019
Insights in the immunobiology of glioblastoma
D Strepkos, M Markouli, A Klonou, C Piperi, AG Papavassiliou 		Journal of Molecular Medicine 2019
Endoplasmic Reticulum Stress Pathway, the Unfolded Protein Response, Modulates Immune Function in the Tumor Microenvironment to Impact Tumor Progression and Therapeutic Response
MU Ramirez, SR Hernandez, DR Soto-Pantoja, KL Cook 		International journal of molecular sciences 2019
RIPK3-Induced Inflammation by I-MDSCs Promotes Intestinal Tumors
A Jayakumar, AL Bothwell 		Cancer research 2019
Wnt Signaling and Its Significance Within the Tumor Microenvironment: Novel Therapeutic Insights
S Patel, A Alam, R Pant, S Chattopadhyay 		Frontiers in immunology 2019
Mouse CD8+NKT-like cells exert dual cytotoxicity against mouse tumor cells and myeloid-derived suppressor cells
Z Li, Y Wu, C Wang, M Zhang 		Cancer Immunology, Immunotherapy 2019
Ferumoxytol Attenuates the Function of MDSCs to Ameliorate LPS-Induced Immunosuppression in Sepsis
Y Xu, Y Xue, X Liu, Y Li, H Liang, H Dou, Y Hou 		Nanoscale research letters 2019
Receptor‐Interacting Protein Kinase 3 Deficiency Recruits Myeloid‐Derived Suppressor Cells to Hepatocellular Carcinoma Through the Chemokine (C‐X‐C Motif) Ligand 1–Chemokine (C‐X‐C Motif) Receptor 2 Axis
YM Li, ZY Liu, JC Wang, JM Yu, ZC Li, HJ Yang, J Tang, ZN Chen 		Hepatology 2019
Role of AHR in the control of GBM-associated myeloid cells
Gabriely G, Quintana FJ 		Seminars in Cancer Biology 2019
1α, 25 Dihydroxyvitamin D (1,25(OH)2D) inhibits the T cell suppressive function of myeloid derived suppressor cells (MDSC)
Fleet JC, Burcham GN, Calvert RD, Elzey BD, Ratliff TL 		The Journal of Steroid Biochemistry and Molecular Biology 2019
Functional assay to assess T-cell inhibitory properties of myeloid derived suppressor cells (MDSCs) isolated from the tumor microenvironment of murine glioma models.
Alghamri MS, Kamran N, Kadiyala P, Lowenstein PR, Castro MG 		Methods in enzymology 2019
Clinical outcomes in non-small-cell lung cancer patients receiving concurrent metformin and immune checkpoint inhibitors
Afzal MZ, Dragnev K, Sarwar T, Shirai K 		Lung Cancer Management 2019
Visualization and quantification of in vivo homing kinetics of myeloid-derived suppressor cells in primary and metastatic cancer.
Hoffmann SHL, Reck DI, Maurer A, Fehrenbacher B, Sceneay JE, Poxleitner M, Öz HH, Ehrlichmann W, Reischl G, Fuchs K, Schaller M, Hartl D, Kneilling M, Möller A, Pichler BJ, Griessinger CM 		Theranostics 2019
A multiscale signalling network map of innate immune response in cancer reveals cell heterogeneity signatures
Kondratova M, Czerwinska U, Sompairac N, Amigorena SD, Soumelis V, Barillot E, Zinovyev A, Kuperstein I 		Nature Communications 2019
A patenting perspective on human neutrophil elastase (HNE) inhibitors (2014-2018) and their therapeutic applications.
Crocetti L, Quinn MT, Schepetkin IA, Giovannoni MP 		Expert Opinion on Therapeutic Patents 2019
Autophagy orchestrates the regulatory program of tumor-associated myeloid-derived suppressor cells
Themis Alissafi, Aikaterini Hatzioannou, Konstantinos Mintzas, Roza Maria Barouni, Aggelos Banos, Sundary Sormendi, Alexandros Polyzos, Maria Xilouri, Ben Wielockx, Helen Gogas, Panayotis Verginis 		Journal of Clinical Investigation 2018
ΔNp63-driven recruitment of myeloid-derived suppressor cells promotes metastasis in triple-negative breast cancer
Sushil Kumar, David Wilkes, Nina Samuel, M. Andres Blanco, Anupma Nayak, Kevin Alicea-Torres, Christian Gluck, Satrajit Sinha, Dmitry I. Gabrilovich, Rumela Chakrabarti 		Journal of Clinical Investigation 2018
Targeted hypoxia reduction restores T cell infiltration and sensitizes prostate cancer to immunotherapy
Priyamvada Jayaprakash, Midan Ai, Arthur Liu, Pratha Budhani, Todd Bartkowiak, Jie Sheng, Casey R Ager, Courtney Nicholas, Ashvin R Jaiswal, Yanqiu Sun, Krishna Shah, Sadhana Balasubramanyam, Nan Li, Guocan Wang, Jing Ning, M. Anna Zal, Tomasz Zal, Michael A. Curran 		Journal of Clinical Investigation 2018
Tumor-derived microRNAs induce myeloid suppressor cells and predict immunotherapy resistance in melanoma
Veronica Huber, Viviana Vallacchi, Viktor Fleming, Xiaoying Hu, Agata Cova, Matteo Dugo, Eriomina Shahaj, Roberta Sulsenti, Elisabetta Vergani, Paola Filipazzi, Angela De Laurentiis, Luca Lalli, Lorenza Di Guardo, Roberto Patuzzo, Barbara Vergani, Elena Casiraghi, Mara Cossa, Ambra V Gualeni, Valentina Bollati, Flavio Arienti, Filippo de Braud, Luigi Mariani, Antonello Villa, Peter Altevogt, Viktor Umansky, Monica Rodolfo, Licia Rivoltini 		Journal of Clinical Investigation 2018
Metformin blocks myeloid-derived suppressor cell accumulation through AMPK-DACH1-CXCL1 axis
G Qin, J Lian, L Huang, Q Zhao, S Liu, Z Zhang, X Chen, D Yue, L Li, F Li, L Wang, V Umansky, B Zhang, S Yang, Y Zhang 		OncoImmunology 2018
Snail promotes ovarian cancer progression by recruiting myeloid-derived suppressor cells via CXCR2 ligand upregulation
M Taki, K Abiko, T Baba, J Hamanishi, K Yamaguchi, R Murakami, K Yamanoi, N Horikawa, Y Hosoe, E Nakamura, A Sugiyama, M Mandai, I Konishi, N Matsumura 		Nature Communications 2018
Plasticity of myeloid-derived suppressor cells in cancer
E Tcyganov, J Mastio, E Chen, DI Gabrilovich 		Current Opinion in Immunology 2018
The inflammatory function of human IgA
IS Hansen, DL Baeten, J den Dunnen 		Cellular and Molecular Life Sciences 2018
Notch Signaling in Myeloid Cells as a Regulator of Tumor Immune Responses
F Hossain, S Majumder, DA Ucar, PC Rodriguez, TE Golde, LM Minter, BA Osborne, L Miele 		Frontiers in immunology 2018
Effects of tumor grade and dexamethasone on myeloid cells in patients with glioma
KW Moyes, A Davis, V Hoglund, K Haberthur, NA Lieberman, SA Kreuser, GH Deutsch, S Franco, D Locke, MO Carleton, DG Gilbertson, R Simmons, C Winter, J Silber, LF Gonzalez-Cuyar, RG Ellenbogen, CA Crane 		OncoImmunology 2018
Targeting Myeloid-Derived Suppressor Cells to Bypass Tumor-Induced Immunosuppression
V Fleming, X Hu, R Weber, V Nagibin, C Groth, P Altevogt, J Utikal, V Umansky 		Frontiers in immunology 2018
Levels of peripheral blood polymorphonuclear myeloid-derived suppressor cells and selected cytokines are potentially prognostic of disease progression for patients with non-small cell lung cancer
L Barrera, E Montes-Servín, JM Hernandez-Martinez, M Orozco-Morales, E Montes-Servín, D Michel-Tello, RA Morales-Flores, D Flores-Estrada, O Arrieta 		Cancer Immunology, Immunotherapy 2018
Contribution to Tumor Angiogenesis From Innate Immune Cells Within the Tumor Microenvironment: Implications for Immunotherapy
A Albini, A Bruno, DM Noonan, L Mortara 		Frontiers in immunology 2018
IL-6 augments IL-4-induced polarization of primary human macrophages through synergy of STAT3, STAT6 and BATF transcription factors
S Gupta, A Jain, SN Syed, RG Snodgrass, B Pflüger-Müller, MS Leisegang, A Weigert, RP Brandes, I Ebersberger, B Brüne, D Namgaladze 		OncoImmunology 2018
Monocytes Differentiate to Immune Suppressive Precursors of Metastasis-Associated Macrophages in Mouse Models of Metastatic Breast Cancer
T Kitamura, D Doughty-Shenton, L Cassetta, S Fragkogianni, D Brownlie, Y Kato, N Carragher, JW Pollard 		Frontiers in immunology 2018
A 2A Adenosine Receptor Gene Deletion or Synthetic A 2A Antagonist Liberate Tumor-Reactive CD8 + T Cells from Tumor-Induced Immunosuppression
J Kjaergaard, S Hatfield, G Jones, A Ohta, M Sitkovsky 		Journal of immunology (Baltimore, Md. : 1950) 2018
Transitory presence of myeloid-derived suppressor cells in neonates is critical for control of inflammation
YM He, X Li, M Perego, Y Nefedova, AV Kossenkov, EA Jensen, V Kagan, YF Liu, SY Fu, QJ Ye, YH Zhou, L Wei, DI Gabrilovich, J Zhou 		Nature Medicine 2018
Efficacy of metformin in combination with immune checkpoint inhibitors (anti-PD-1/anti-CTLA-4) in metastatic malignant melanoma
MZ Afzal, RR Mercado, K Shirai 		Journal for ImmunoTherapy of Cancer 2018
S100A4 Protects Myeloid-Derived Suppressor Cells from Intrinsic Apoptosis via TLR4–ERK1/2 Signaling
Q Li, C Dai, R Xue, P Wang, L Chen, Y Han, U Erben, Z Qin 		Frontiers in immunology 2018
Tumor matrix remodeling and novel immunotherapies: the promise of matrix-derived immune biomarkers
MU Mushtaq, A Papadas, A Pagenkopf, E Flietner, Z Morrow, SG Chaudhary, F Asimakopoulos 		Journal for ImmunoTherapy of Cancer 2018
Expansion of Granulocytic, Myeloid-Derived Suppressor Cells in Response to Ethanol-Induced Acute Liver Damage
S Li, N Wang, HY Tan, M Hong, MF Yuen, H Li, Y Feng 		Frontiers in immunology 2018
Polymorphonuclear Leukocytes in Pulmonary Hypertension and Fibrosis: Not Always What They Appear to Be
N Durmus, G Grunig 		American journal of respiratory cell and molecular biology 2018
NRF2 Is One of the Players Involved in Bone Marrow Mediated Drug Resistance in Multiple Myeloma
CH Yen, HH Hsiao 		International journal of molecular sciences 2018
Prospects for chimeric antigen receptor-modified T cell therapy for solid tumors
E Zhang, J Gu, H Xu 		Molecular Cancer 2018
STAT3 in Tumor-Associated Myeloid Cells: Multitasking to Disrupt Immunity
YL Su, S Banerjee, S White, M Kortylewski 		International journal of molecular sciences 2018
Dietary Protein Restriction Reprograms Tumor-Associated Macrophages and Enhances Immunotherapy
A Orillion, NP Damayanti, L Shen, R Adelaiye-Ogala, H Affronti, M Elbanna, S Chintala, M Ciesielski, L Fontana, C Kao, BD Elzey, TL Ratliff, DE Nelson, D Smiraglia, SI Abrams, R Pili 		Clinical cancer research 2018
Tumor-infiltrating Treg, MDSC, and IDO expression associated with outcomes of neoadjuvant chemotherapy of breast cancer
F Li, Y Zhao, L Wei, S Li, J Liu 		Cancer biology & therapy 2018
Neutrophil elastase in the tumor microenvironment
I Lerman, SR Hammes 		Steroids 2018
MDSCs drive the process of endometriosis by enhancing angiogenesis and are a new potential therapeutic target
T Zhang, J Zhou, GC Man, KT Leung, B Liang, B Xiao, X Ma, S Huang, H Huang, VL Hegde, Y Zhong, Y Li, GW Kong, AK Yiu, J Kwong, PC Ng, PS Nagarkatti, M Nagarkatti, CC Wang 		European Journal of Immunology 2018
Myeloid-derived suppressor cells are bound and inhibited by anti-thymocyte globulin
YS Lee, E Davila, T Zhang, HP Milmoe, SN Vogel, JS Bromberg, JR Scalea 		Innate immunity 2018
Metastatic niche functions and therapeutic opportunities
T Celià-Terrassa, Y Kang 		Nature Cell Biology 2018
Aging Mouse Models Reveal Complex Tumor-Microenvironment Interactions in Cancer Progression
H Mori, RD Cardiff, AD Borowsky 		Frontiers in Cell and Developmental Biology 2018
The level of myeloid-derived suppressor cells positively correlates with regulatory T cells in the blood of children with transient hypogammaglobulinaemia of infancy
I Siemińska, M Rutkowska-Zapała, K Bukowska-Strakova, A Gruca, A Szaflarska, K Kobylarz, M Siedlar, J Baran 		CENT EUR J IMMUNOL 2018
Perspectives of Immune Suppression in the Tumor Microenvironment Promoting Oral Malignancy
N Kondoh, M Mizuno-Kamiya, E Takayama, H Kawati, N Umemura, Y Yamazaki, K Mitsudo, I Tohnai 		The open dentistry journal 2018
The neutrophil: one cell on many missions or many cells with different agendas?
G Christoffersson, M Phillipson 		Cell and Tissue Research 2018
Tumour-elicited neutrophils engage mitochondrial metabolism to circumvent nutrient limitations and maintain immune suppression
CM Rice, LC Davies, JJ Subleski, N Maio, M Gonzalez-Cotto, C Andrews, NL Patel, EM Palmieri, JM Weiss, JM Lee, CM Annunziata, TA Rouault, SK Durum, DW McVicar 		Nature Communications 2018
Concomitant type I IFN and M-CSF signaling reprograms monocyte differentiation and drives pro-tumoral arginase production
Y Tong, L Zhou, L Yang, P Guo, Y Cao, FX Qin, J Liu 		EBioMedicine 2018
Entinostat Converts Immune-Resistant Breast and Pancreatic Cancers into Checkpoint-Responsive Tumors by Reprogramming Tumor-Infiltrating MDSCs
BJ Christmas, CI Rafie, AC Hopkins, BA Scott, HS Ma, KA Cruz, S Woolman, TD Armstrong, RM Connolly, NA Azad, EM Jaffee, ET Torres 		Cancer immunology research 2018
Caspase-1 from Human Myeloid-Derived Suppressor Cells Can Promote T Cell–Independent Tumor Proliferation
Q Zeng, J Fu, M Korrer, M Gorbounov, PJ Murray, D Pardoll, DL Masica, YJ Kim 		Cancer immunology research 2018
Breast and pancreatic cancer interrupt IRF8-dependent dendritic cell development to overcome immune surveillance
MA Meyer, JM Baer, BL Knolhoff, TM Nywening, RZ Panni, X Su, KN Weilbaecher, WG Hawkins, C Ma, RC Fields, DC Linehan, GA Challen, R Faccio, RL Aft, DG DeNardo 		Nature Communications 2018
Myeloid-derived suppressor cells coming of age
F Veglia, M Perego, D Gabrilovich 		Nature Immunology 2018
Adaptive NK cells resist regulatory T cell suppression driven by IL-37
D Sarhan, KL Hippen, A Lemire, S Hying, X Luo, T Lenvik, J Curtsinger, Z Davis, B Zhang, S Cooley, F Cichocki, BR Blazar, JS Miller 		Cancer immunology research 2018
Tumor Hypoxia As an Enhancer of Inflammation-Mediated Metastasis: Emerging Therapeutic Strategies
JW DiGiacomo, DM Gilkes 		Targeted Oncology 2018
Long term impact of CTLA4 blockade immunotherapy on regulatory and effector immune responses in patients with melanoma
J Retseck, A Nasr, Y Lin, H Lin, P Mendiratta, LH Butterfield, AA Tarhini 		Journal of Translational Medicine 2018
Immunosuppressive monocytes (CD14+/HLA-DRlow/−) increase in childhood precursor B-cell acute lymphoblastic leukemia after induction chemotherapy
DS Lima, RP Lemes, DM Matos 		Medical Oncology 2018
A preclinical model to investigate the role of surgically-induced inflammation in tumor responses to intraoperative photodynamic therapy: PRECLINICAL MODEL OF SURGICAL INFLAMMATION
RW Davis, E Papasavvas, A Klampatsa, M Putt, LJ Montaner, MJ Culligan, S McNulty, JS Friedberg, CB Simone, S Singhal, SM Albelda, KA Cengel, TM Busch 		Lasers in Surgery and Medicine 2018
The multi-receptor inhibitor axitinib reverses tumor-induced immunosuppression and potentiates treatment with immune-modulatory antibodies in preclinical murine models
H Läubli, P Müller, L DAmico, M Buchi, AS Kashyap, A Zippelius 		Cancer Immunology, Immunotherapy 2018
Aberrant erythropoiesis fuels tumor growth
K Nakamura, MJ Smyth 		Cell Research 2018
Microarray analysis of long non-coding RNA expression profiles in monocytic myeloid-derived suppressor cells in Echinococcus granulosus-infected mice
A Yu, Y Wang, J Yin, J Zhang, S Cao, J Cao, Y Shen 		Parasites & vectors 2018
Protective immunity elicited by measles vaccine exerts anti-tumor effects on measles virus hemagglutinin gene-modified cancer cells in a mouse model
Y Qi, K Xing, L Zhang, F Zhao, M Yao, A Hu, X Wu 		Journal of Cancer Research and Clinical Oncology 2018
Tumour YAP1 and PTEN expression correlates with tumour-associated myeloid suppressor cell expansion and reduced survival in colorectal cancer
R Yang, T Cai, X Wu, Y Liu, J He, X Zhang, G Ma, J Li 		Immunology 2018
Assessing the Role of DNA Methylation-Derived Neutrophil-to-Lymphocyte Ratio in Rheumatoid Arthritis
S Ambatipudi, GC Sharp, SL Clarke, D Plant, JH Tobias, DM Evans, A Barton, CL Relton 		Journal of Immunology Research 2018
The Shifting Paradigm of Prognostic Factors of Colorectal Liver Metastases: From Tumor-Centered to Host Immune-Centered Factors
M Donadon, A Lleo, LD Tommaso, C Soldani, B Franceschini, M Roncalli, G Torzilli 		Frontiers in Oncology 2018
New opportunities for nanoparticles in cancer immunotherapy
W Park, YJ Heo, DK Han 		Biomaterials Research 2018
Histamine targets myeloid-derived suppressor cells and improves the anti-tumor efficacy of PD-1/PD-L1 checkpoint blockade
HG Wiktorin, MS Nilsson, R Kiffin, FE Sander, B Lenox, A Rydström, K Hellstrand, A Martner 		Cancer Immunology, Immunotherapy 2018
Immunosuppressive circuits in tumor microenvironment and their influence on cancer treatment efficacy
A Tuccitto, E Shahaj, E Vergani, S Ferro, V Huber, M Rodolfo, C Castelli, L Rivoltini, V Vallacchi 		Virchows Archiv 2018
AAV-Vectored Fms-Related Tyrosine Kinase 3 Ligand Inhibits CD34+ Progenitor Cell Engraftment in Humanized Mice
L Ling, X Tang, X Huang, J Li, H Wang, Z Chen 		Journal of Neuroimmune Pharmacology 2018
Intratumoral delivery of antigen with complement C3-bound liposomes reduces tumor growth in mice
A Francian, S Namen, M Stanley, K Mann, H Martinson, M Kullberg 		Nanomedicine : nanotechnology, biology, and medicine 2018
Microenvironmental oxygen pressure orchestrates an anti- and pro-tumoral γδ T cell equilibrium via tumor-derived exosomes
L Li, B Cao, X Liang, S Lu, H Luo, Z Wang, S Wang, J Jiang, J Lang, G Zhu 		Oncogene 2018
The failure of radical treatments to cure cancer: can less deliver more?
AG Dalgleish, PL Stern 		2018
Computational Immune Monitoring Reveals Abnormal Double-Negative T Cells Present across Human Tumor Types
AR Greenplate, DD McClanahan, BK Oberholtzer, DB Doxie, CE Roe, KE Diggins, N Leelatian, ML Rasmussen, MC Kelley, V Gama, PJ Siska, JC Rathmell, PB Ferrell, DB Johnson, JM Irish 		Cancer immunology research 2018
Prostaglandin E2 produced by myeloid-derived suppressive cells induces cancer stem cells in uterine cervical cancer
H Kuroda, S Mabuchi, E Yokoi, N Komura, K Kozasa, Y Matsumoto, M Kawano, R Takahashi, T Sasano, K Shimura, M Kodama, K Hashimoto, K Sawada, E Morii, T Kimura 		Oncotarget 2018
Establishment of malignantly transformed dendritic cell line SU3-ihDCTC induced by Glioma stem cells and study on its sensitivity to resveratrol
X Fei, A Wang, D Wang, X Meng, J Ma, L Hong, R Qin, A Wang, J Dong, Q Huang, Z Wang 		BMC Immunology 2018
Autocrine TGFβ Is a Survival Factor for Monocytes and Drives Immunosuppressive Lineage Commitment
A Gonzalez-Junca, KE Driscoll, I Pellicciotta, S Du, CH Lo, R Roy, R Parry, I Tenvooren, DM Marquez, MH Spitzer, MH Barcellos-Hoff 		Cancer immunology research 2018
Combining immunotherapy with radiation therapy in thoracic oncology
SN Badiyan, MC Roach, MD Chuong, SR Rice, NE Onyeuku, J Remick, S Chilukuri, E Glass, P Mohindra, CB Simone 		Journal of Thoracic Disease 2018
Interferon-γ and Colorectal Cancer: an up-to date
C Kosmidis, K Sapalidis, T Koletsa, M Kosmidou, C Efthimiadis, G Anthimidis, N Varsamis, N Michalopoulos, C Koulouris, S Atmatzidis, L Liavas, TM Strati, G Koimtzis, A Tsakalidis, S Mantalovas, K Zarampouka, M Florou, DE Giannakidis, E Georgakoudi, S Baka, P Zarogoulidis, YG Man, I Kesisoglou 		Journal of Cancer 2018
Salidroside prevents skin carcinogenesis induced by DMBA/TPA in a mouse model through suppression of inflammation and promotion of apoptosis.
Kong YH, Xu SP 		Oncology reports 2018
Chromogenic Multiplex Immunohistochemistry Reveals Modulation of the Immune Microenvironment Associated with Survival in Elderly Patients with Lung Adenocarcinoma.
Ilié M, Beaulande M, Ben Hadj S, Chamorey E, Schiappa R, Long-Mira E, Lassalle S, Butori C, Cohen C, Leroy S, Guérin O, Mouroux J, Marquette CH, Pomerol JF, Erb G, Hofman V, Hofman P 		Cancers 2018
Resveratrol ameliorates Lewis lung carcinoma‐bearing mice development, decreases granulocytic myeloid‐derived suppressor cell accumulation and impairs its suppressive ability
Zhao Y, Shao Q, Zhu H, Xu H, Long W, Yu B, Zhou L, Xu H, Wu Y, Su Z 		Cancer Science 2018
Reduction of myeloid-derived suppressor cells reinforces the anti-solid tumor effect of recipient leukocyte infusion in murine neuroblastoma-bearing allogeneic bone marrow chimeras
Dierckx de Casterlé I, Fevery S, Rutgeerts O, Poosti F, Struyf S, Lenaerts C, Waer M, Billiau AD, Sprangers B 		Cancer Immunology, Immunotherapy 2018
Interactions among myeloid regulatory cells in cancer
Umansky V, Adema GJ, Baran J, Brandau S, Van Ginderachter JA, Hu X, Jablonska J, Mojsilovic S, Papadaki HA, Pico de Coaña Y, Santegoets KC, Santibanez JF, Serre K, Si Y, Sieminska I, Velegraki M, Fridlender ZG 		Cancer Immunology, Immunotherapy 2018
Role of ILC2-modulated T-cell/MDSC balance in bladder cancer recurrence
Mathieu Chevalier, Sara Trabanelli, Julien Racle, Bérengère Salomé, Valérie Cesson, Dalila Gharbi, Perrine Bohner, Sonia Domingos-Pereira, Florence Dartiguenave, Anne-Sophie Fritschi, Daniel Speiser, Cyrill Rentsch, David Gfeller, Patrice Jichlinski, Denise Nardelli-Haefliger, Camilla Jandus, Laurent Derré 		Journal of Clinical Investigation 2017
Neutralization of IL-8 decreases tumor PMN-MDSCs and reduces mesenchymalization of claudin-low triple negative breast cancer
Charli Dominguez, Kristen McCampbell, Justin David, Claudia Palena 		JCI Insight 2017
The protumorigenic potential of FTY720 by promoting extramedullary hematopoiesis and MDSC accumulation
Y Li, T Zhou, Y Wang, C Ning, Z Lv, G Han, JC Morris, EN Taylor, R Wang, H Xiao, C Hou, Y Ma, B Shen, J Feng, R Guo, Y Li, G Chen 		Oncogene 2017
Local Activation of p53 in the Tumor Microenvironment Overcomes Immune Suppression and Enhances Antitumor Immunity
G Guo, M Yu, W Xiao, E Celis, Y Cui 		Cancer research 2017
LMP1-mediated glycolysis induces myeloid-derived suppressor cell expansion in nasopharyngeal carcinoma
TT Cai, SB Ye, YN Liu, J He, QY Chen, HQ Mai, CX Zhang, J Cui, XS Zhang, P Busson, YX Zeng, J Li, R Longnecker 		PLoS pathogens 2017
Targeting Autocrine CCL5–CCR5 Axis Reprograms Immunosuppressive Myeloid Cells and Reinvigorates Antitumor Immunity
Y Ban, J Mai, X Li, M Mitchell-Flack, T Zhang, L Zhang, L Chouchane, M Ferrari, H Shen, X Ma 		Cancer research 2017
Extracellular matrix and the myeloid-in-myeloma compartment: balancing tolerogenic and immunogenic inflammation in the myeloma niche
F Asimakopoulos, C Hope, MG Johnson, A Pagenkopf, K Gromek, B Nagel 		Journal of leukocyte biology 2017
Natural killer cells unleashed: Checkpoint receptor blockade and BiKE/TriKE utilization in NK-mediated anti-tumor immunotherapy
ZB Davis, DA Vallera, JS Miller, M Felices 		Seminars in Immunology 2017
Arginase inhibition suppresses lung metastasis in the 4T1 breast cancer model independently of the immunomodulatory and anti-metastatic effects of VEGFR-2 blockade
C Secondini, O Coquoz, L Spagnuolo, T Spinetti, S Peyvandi, L Ciarloni, F Botta, C Bourquin, C Rüegg 		OncoImmunology 2017
A Relay Pathway between Arginine and Tryptophan Metabolism Confers Immunosuppressive Properties on Dendritic Cells
G Mondanelli, R Bianchi, MT Pallotta, C Orabona, E Albini, A Iacono, ML Belladonna, C Vacca, F Fallarino, A Macchiarulo, S Ugel, V Bronte, F Gevi, L Zolla, A Verhaar, M Peppelenbosch, EM Mazza, S Bicciato, Y Laouar, L Santambrogio, P Puccetti, C Volpi, U Grohmann 		Immunity 2017
Identifying baseline immune-related biomarkers to predict clinical outcome of immunotherapy
S Gnjatic, V Bronte, LR Brunet, MO Butler, ML Disis, J Galon, LG Hakansson, BA Hanks, V Karanikas, SN Khleif, JM Kirkwood, LD Miller, DJ Schendel, I Tanneau, JM Wigginton, LH Butterfield 		Journal for ImmunoTherapy of Cancer 2017
Exogenous Lipid Uptake Induces Metabolic and Functional Reprogramming of Tumor-Associated Myeloid-Derived Suppressor Cells
AA Al-Khami, L Zheng, LD Valle, F Hossain, D Wyczechowska, J Zabaleta, MD Sanchez-Pino, MJ Dean, PC Rodriguez, AC Ochoa 		OncoImmunology 2017
HYPE or HOPE: the prognostic value of infiltrating immune cells in cancer
TA Barnes, E Amir 		British Journal of Cancer 2017
Cancer Immunotherapy: Whence and Whither
PJ Stambrook, J Maher, F Farzaneh 		Molecular cancer research : MCR 2017
Differentiation of Myeloid-derived Suppressor Cells from Murine Bone Marrow and Their Co-culture with Splenic Dendritic Cells
G Mondanelli, C Volpi 		Bio-protocol 2017
Radiotherapy and immunotherapy: a beneficial liaison?
RR Weichselbaum, H Liang, L Deng, YX Fu 		Nature Reviews Clinical Oncology 2017
Engineering Chimeric Antigen Receptor T-Cells for Racing in Solid Tumors: Don’t Forget the Fuel
M Irving, RV de Silly, K Scholten, N Dilek, G Coukos 		Frontiers in immunology 2017
Cancer Immunotherapies: Are They as Effective in the Elderly?
K Poropatich, J Fontanarosa, S Samant, JA Sosman, B Zhang 		Drugs & Aging 2017
HIF-1α is a key regulator in potentiating suppressor activity and limiting the microbicidal capacity of MDSC-like cells during visceral leishmaniasis
A Hammami, BM Abidin, T Charpentier, A Fabié, AP Duguay, KM Heinonen, S Stäger, D Sacks 		PLoS pathogens 2017
Tumor regulation of the tissue environment in the liver
T Eggert, TF Greten 		Pharmacology & Therapeutics 2017
Monocytic myeloid-derived suppressor cells regulate T-cell responses against vaccinia virus
C Fortin, Y Yang, X Huang 		European Journal of Immunology 2017
The innate and adaptive infiltrating immune systems as targets for breast cancer immunotherapy
AM Law, E Lim, CJ Ormandy, D Gallego-Ortega 		Endocrine Related Cancer 2017
Tuning cancer fate: the unremitting role of host immunity
B Calì, B Molon, A Viola 		Open Biology 2017
Cancer vaccine based on a combination of an infection-enhanced adenoviral vector and pro-inflammatory allogeneic DCs leads to sustained antigen-specific immune responses in three melanoma models
G Fotaki, C Jin, IK Kerzeli, M Ramachandran, MM Martikainen, A Karlsson-Parra, D Yu, M Essand 		OncoImmunology 2017
Myeloid cells as a target for oligonucleotide therapeutics: turning obstacles into opportunities
M Kortylewski, D Moreira 		Cancer Immunology, Immunotherapy 2017
A standardized herbal extract mitigates tumor inflammation and augments chemotherapy effect of docetaxel in prostate cancer
CH Tsai, SF Tzeng, SC Hsieh, YC Yang, YW Hsiao, MH Tsai, PW Hsiao 		Scientific Reports 2017
The Emerging Roles of Extracellular Vesicles As Communication Vehicles within the Tumor Microenvironment and Beyond
R Sullivan, G Maresh, X Zhang, C Salomon, J Hooper, D Margolin, L Li 		Frontiers in Endocrinology 2017
Toll-like receptor 2 ligand and interferon-γ suppress anti-tumor T cell responses by enhancing the immunosuppressive activity of monocytic myeloid-derived suppressor cells
H Shime, A Maruyama, S Yoshida, Y Takeda, M Matsumoto, T Seya 		OncoImmunology 2017
CXCR2+ MDSCs promote breast cancer progression by inducing EMT and activated T cell exhaustion
H Zhu, Y Gu, Y Xue, M Yuan, X Cao, Q Liu 		Oncotarget 2017
Immunosuppressive Myeloid Cells’ Blockade in the Glioma Microenvironment Enhances the Efficacy of Immune-Stimulatory Gene Therapy
N Kamran, P Kadiyala, M Saxena, M Candolfi, Y Li, MA Moreno-Ayala, N Raja, D Shah, PR Lowenstein, MG Castro 		Molecular Therapy 2017
IRF7 regulates the development of granulocytic myeloid-derived suppressor cells through S100A9 transrepression in cancer
Q Yang, X Li, H Chen, Y Cao, Q Xiao, Y He, J Wei, J Zhou 		Oncogene 2017
Monocytic and granulocytic myeloid derived suppressor cells differentially regulate spatiotemporal tumour plasticity during metastatic cascade
M Ouzounova, E Lee, R Piranlioglu, AE Andaloussi, R Kolhe, MF Demirci, D Marasco, I Asm, A Chadli, KA Hassan, M Thangaraju, G Zhou, AS Arbab, JK Cowell, H Korkaya 		Nature Communications 2017
New insights into the role of EMT in tumor immune escape
S Terry, P Savagner, S Ortiz-Cuaran, L Mahjoubi, P Saintigny, JP Thiery, S Chouaib 		Molecular Oncology 2017
The STING agonist DMXAA triggers a cooperation between T lymphocytes and myeloid cells that leads to tumor regression
JM Weiss, MV Guerin, F Regnier, G Renault, I Galy-Fauroux, L Vimeux, V Feuillet, E Peranzoni, M Thoreau, A Trautmann, N Bercovici 		OncoImmunology 2017
Inferring the Impact of Regulatory Mechanisms that Underpin CD8+ T Cell Control of B16 Tumor Growth In vivo Using Mechanistic Models and Simulation
DJ Klinke, Q Wang 		Frontiers in pharmacology 2017
Entinostat Neutralizes Myeloid-Derived Suppressor Cells and Enhances the Antitumor Effect of PD-1 Inhibition in Murine Models of Lung and Renal Cell Carcinoma
A Orillion, A Hashimoto, N Damayanti, L Shen, R Adelaiye-Ogala, S Arisa, S Chintala, P Ordentlich, C Kao, B Elzey, D Gabrilovich, R Pili 		Clinical cancer research 2017
Immune Surveillance in Melanoma: From immune attack to melanoma escape and even counterattack
F Mahmoud, B Shields, I Makhoul, N Avaritt, HK Wong, LF Hutchins, S Shalin, AJ Tackett 		Cancer biology & therapy 2017
Therapeutic reduction of cell-mediated immunosuppression in mycosis fungoides and Sézary syndrome
LJ Geskin, OE Akilov, S Kwon, M Schowalter, S Watkins, TL Whiteside, LH Butterfield, LD Falo 		Cancer Immunology, Immunotherapy 2017
Arachidonic Acid Metabolite as a Novel Therapeutic Target in Breast Cancer Metastasis
T Borin, K Angara, M Rashid, B Achyut, A Arbab 		International journal of molecular sciences 2017
Immune engineering: from systems immunology to engineering immunity
N Jiang 		Current Opinion in Biomedical Engineering 2017
Chemotherapy and tumor microenvironment of pancreatic cancer
Q Liu, Q Liao, Y Zhao 		Cancer Cell International 2017
Ascites-derived IL-6 and IL-10 synergistically expand CD14+HLA-DR-/low myeloid-derived suppressor cells in ovarian cancer patients
L Wu, Z Deng, Y Peng, L Han, J Liu, L Wang, B Li, J Zhao, S Jiao, H Wei 		Oncotarget 2017
CXCR2 deficient mice display macrophage-dependent exaggerated acute inflammatory responses
DP Dyer, K Pallas, LM Ruiz, F Schuette, GJ Wilson, GJ Graham 		Scientific Reports 2017
Deep Immune Profiling of an Arginine-Enriched Nutritional Intervention in Patients Undergoing Surgery
N Aghaeepour, C Kin, EA Ganio, KP Jensen, DK Gaudilliere, M Tingle, A Tsai, HL Lancero, B Choisy, LS McNeil, R Okada, AA Shelton, GP Nolan, MS Angst, BL Gaudilliere 		Journal of immunology (Baltimore, Md. : 1950) 2017
miRNAs, Melanoma and Microenvironment: An Intricate Network
G Romano, L Kwong 		International journal of molecular sciences 2017
Demethylating agent decitabine disrupts tumor-induced immune tolerance by depleting myeloid-derived suppressor cells
J Zhou, Y Yao, Q Shen, G Li, L Hu, X Zhang 		Journal of Cancer Research and Clinical Oncology 2017
Mechanisms overseeing myeloid-derived suppressor cell production in neoplastic disease
CS Netherby, SI Abrams 		Cancer Immunology, Immunotherapy 2017
Human Myeloid-derived Suppressor Cells are Associated With Chronic Immune Suppression After Severe Sepsis/Septic Shock:
B Mathias, AL Delmas, T Ozrazgat-Baslanti, EL Vanzant, BE Szpila, AM Mohr, FA Moore, SC Brakenridge, BA Brumback, LL Moldawer, PA Efron 		Annals of Surgery 2017
Toca 511 gene transfer and treatment with the prodrug, 5-fluorocytosine, promotes durable antitumor immunity in a mouse glioma model
LA Mitchell, FL Espinoza, D Mendoza, Y Kato, A Inagaki, K Hiraoka, N Kasahara, HE Gruber, DJ Jolly, JM Robbins 		Neuro-Oncology 2017
Circulating myeloid-derived suppressor cells predict disease activity and treatment response in patients with immune thrombocytopenia
J Zhou, Y Zhou, J Wen, X Sun, X Zhang 		Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas / Sociedade Brasileira de Biofisica ... [et al.] 2017
MDSCs are involved in the protumorigenic potentials of GM-CSF in colitis-associated cancer
N Ma, Q Liu, L Hou, Y Wang, Z Liu 		International journal of immunopathology and pharmacology 2017
Chemotherapeutic agent-mediated elimination of myeloid-derived suppressor cells
Z Wang, B Till, Q Gao 		OncoImmunology 2017
Zoledronic acid inhibits NFAT and IL-2 signaling pathways in regulatory T cells and diminishes their suppressive function in patients with metastatic cancer
D Sarhan, C Leijonhufvud, S Murray, K Witt, C Seitz, M Wallerius, H Xie, A Ullén, U Harmenberg, E Lidbrink, C Rolny, J Andersson, A Lundqvist 		OncoImmunology 2017
Stat6 Promotes Intestinal Tumorigenesis in a Mouse Model of Adenomatous Polyposis by Expansion of MDSCs and Inhibition of Cytotoxic CD8 Response
A Jayakumar, AL Bothwell 		Neoplasia (New York, N.Y.) 2017
Biocompatibility of HbV: Liposome-Encapsulated Hemoglobin Molecules-Liposome Effects on Immune Function
H Azuma, M Fujihara, H Sakai 		Journal of Functional Biomaterials 2017
Blocking C5aR signaling promotes the anti-tumor efficacy of PD-1/PD-L1 blockade
H Zha, X Han, Y Zhu, F Yang, Y Li, Q Li, B Guo, B Zhu 		OncoImmunology 2017
Granulocytic myeloid-derived suppressor cells suppress virus-specific CD8+ T cell responses during acute Friend retrovirus infection
M Drabczyk-Pluta, T Werner, D Hoffmann, Q Leng, L Chen, U Dittmer, G Zelinskyy 		Retrovirology 2017
Pilot Study of Whole Blood MicroRNAs as Potential Tools for Diffuse Low-Grade Gliomas Detection
C Gozé, C Reynes, L Forestier, R Sabatier, H Duffau 		Cellular and Molecular Neurobiology 2017
The DNA Methylcytosine Dioxygenase Tet2 Sustains Immunosuppressive Function of Tumor-Infiltrating Myeloid Cells to Promote Melanoma Progression
W Pan, S Zhu, K Qu, K Meeth, J Cheng, K He, H Ma, Y Liao, X Wen, C Roden, Z Tobiasova, Z Wei, J Zhao, J Liu, J Zheng, B Guo, SA Khan, M Bosenberg, RA Flavell, J Lu 		Immunity 2017
Collagen I enhances the efficiency and anti-tumor activity of dendritic-tumor fusion cells
J He, R Zheng, Z Zhang, J Tan, C Zhou, G Zhang, X Jiang, Q Sun, S Zhou, D Zheng, Y Huang, L Wu, Z Lai, J Li, N Yang, X Lu, Y Zhao 		OncoImmunology 2017
Calreticulin Fragment 39-272 Promotes B16 Melanoma Malignancy through Myeloid-Derived Suppressor Cells In Vivo
XY He, FY Gong, Y Chen, Z Zhou, Z Gong, XM Gao 		Frontiers in immunology 2017
Neutrophils Slow Disease Progression in Murine Lupus via Modulation of Autoreactive Germinal Centers
AK Bird, M Chang, J Barnard, BI Goldman, N Meednu, J Rangel-Moreno, JH Anolik 		Journal of immunology (Baltimore, Md. : 1950) 2017
Infiltrating Myeloid Cells Exert Protumorigenic Actions via Neutrophil Elastase
I Lerman, ML la Garcia-Hernandez, J Rangel-Moreno, L Chiriboga, C Pan, KL Nastiuk, JJ Krolewski, A Sen, SR Hammes 		Molecular cancer research : MCR 2017
Mesenchymal stromal cells promote B-cell lymphoma in lacrimal glands by inducing immunosuppressive microenvironment
MJ Lee, SY Park, JH Ko, HJ Lee, JS Ryu, JW Park, SI Khwarg, SO Yoon, JY Oh 		Oncotarget 2017
Exosomal tetraspanins mediate cancer metastasis by altering host microenvironment
J Lu, J Li, S Liu, T Wang, A Ianni, E Bober, T Braun, R Xiang, S Yue 		Oncotarget 2017
Synergistic Immunostimulatory Effects and Therapeutic Benefit of Combined Histone Deacetylase and Bromodomain Inhibition in Non–Small Cell Lung Cancer
DO Adeegbe, Y Liu, PH Lizotte, Y Kamihara, AR Aref, C Almonte, R Dries, Y Li, S Liu, X Wang, T Warner-Hatten, J Castrillon, GC Yuan, N Poudel-Neupane, H Zhang, JL Guerriero, S Han, MM Awad, DA Barbie, J Ritz, SS Jones, PS Hammerman, J Bradner, SN Quayle, KK Wong 		Cancer Discovery 2017
Clinical Features of Acquired Resistance to Anti–PD-1 Therapy in Advanced Melanoma
DY Wang, Z Eroglu, A Ozgun, PD Leger, S Zhao, F Ye, JJ Luke, RW Joseph, R Haq, PA Ott, FS Hodi, JA Sosman, DB Johnson, EI Buchbinder 		Cancer immunology research 2017
Activation of VIP signaling enhances immunosuppressive effect of MDSCs on CMV-induced adaptive immunity
P Forghani, CT Petersen, EK Waller 		Oncotarget 2017
Serial pseudoprogression of metastatic malignant melanoma in a patient treated with nivolumab: a case report
Y Ozaki, J Shindoh, Y Miura, H Nakajima, R Oki, M Uchiyama, J Masuda, K Kinowaki, C Kondoh, Y Tanabe, T Tanaka, S Haruta, M Ueno, S Kitano, T Fujii, H Udagawa, T Takano 		BMC Cancer 2017
Immune microenvironment of experimental rat C6 gliomas resembles human glioblastomas
A Gieryng, D Pszczolkowska, K Bocian, M Dabrowski, WD Rajan, M Kloss, J Mieczkowski, B Kaminska 		Scientific Reports 2017
Immunotherapies for malignant glioma
VA Boussiotis, A Charest 		Oncogene 2017
CD14 + CD15 - HLA-DR - myeloid-derived suppressor cells impair antimicrobial responses in patients with acute-on-chronic liver failure
C Bernsmeier, E Triantafyllou, R Brenig, FJ Lebosse, A Singanayagam, VC Patel, OT Pop, W Khamri, R Nathwani, R Tidswell, CJ Weston, DH Adams, MR Thursz, JA Wendon, CG Antoniades 		Gut 2017
LncRNA RNCR3 promotes Chop expression by sponging miR-185-5p during MDSC differentiation
W Shang, Z Tang, Y Gao, H Qi, X Su, Y Zhang, R Yang 		Oncotarget 2017
Myeloid-derived cells in prostate cancer progression: phenotype and prospective therapies
Z Lopez-Bujanda, CG Drake 		Journal of leukocyte biology 2017
Immunotherapy for Breast Cancer: Current and Future Strategies
Williams AD, Payne KK, Posey AD Jr, Hill C, Conejo-Garcia J, June CH, Tchou J 		Current Surgery Reports 2017
Melanoma induced immunosuppression is mediated by hematopoietic dysregulation.
Kamran N, Li Y, Sierra M, Alghamri MS, Kadiyala P, Appelman HD, Edwards M, Lowenstein PR, Castro MG 		OncoImmunology 2017
Identifying a Clinically Applicable Mutational Burden Threshold as a Potential Biomarker of Response to Immune Checkpoint Therapy in Solid Tumors
Panda A, Betigeri A, Subramanian K, Ross JS, Pavlick DC, Ali S, Markowski P, Silk A, Kaufman HL, Lattime E, Mehnert JM, Sullivan R, Lovly CM, Sosman J, Johnson DB, Bhanot G, Ganesan S 		JCO Precision Oncology 2017
Systematic Pan-Cancer Analysis Reveals Immune Cell Interactions in the Tumor Microenvironment.
Varn FS, Wang Y, Mullins DW, Fiering S, Cheng C 		Cancer research 2017
Tumor Immuno-Environment in Cancer Progression and Therapy.
Kalinski P, Talmadge JE 		Advances in experimental medicine and biology 2017
Acquired resistance to immune clearance promotes Klebsiella pneumoniae ST258 infection
Danielle Ahn, Hernán Peñaloza, Zheng Wang, Matthew Wickersham, Dane Parker, Purvi Patel, Antonius Koller, Emily Chen, Susan Bueno, Anne-Catrin Uhlemann, Alice S. Prince 		JCI Insight 2016
Selective Targeting of Myeloid-Derived Suppressor Cells in Cancer Patients Using DS-8273a, an Agonistic TRAIL-R2 Antibody
GA Dominguez, T Condamine, S Mony, A Hashimoto, F Wang, Q Liu, A Forero, J Bendell, R Witt, N Hockstein, P Kumar, DI Gabrilovich 		Clinical cancer research 2016
Adaptive NK Cells with Low TIGIT Expression Are Inherently Resistant to Myeloid-Derived Suppressor Cells
D Sarhan, F Cichocki, B Zhang, A Yingst, SR Spellman, S Cooley, MR Verneris, BR Blazar, JS Miller 		Cancer research 2016
Immune targets and neoantigens for cancer immunotherapy and precision medicine
RF Wang, HY Wang 		Cell Research 2016
Immune suppressive mechanisms in the tumor microenvironment
DH Munn, V Bronte 		Current Opinion in Immunology 2016
Recommendations for myeloid-derived suppressor cell nomenclature and characterization standards
V Bronte, S Brandau, SH Chen, MP Colombo, AB Frey, TF Greten, S Mandruzzato, PJ Murray, A Ochoa, S Ostrand-Rosenberg, PC Rodriguez, A Sica, V Umansky, RH Vonderheide, DI Gabrilovich 		Nature Communications 2016
Relevance of Interferon Regulatory Factor-8 Expression in Myeloid–Tumor Interactions
SI Abrams, CS Netherby, DY Twum, MN Messmer 		Journal of Interferon & Cytokine Research 2016
The Nature of Myeloid-Derived Suppressor Cells in the Tumor Microenvironment
V Kumar, S Patel, E Tcyganov, DI Gabrilovich 		Trends in Immunology 2016
Immunological battlefield in gastric cancer and role of immunotherapies
M Wang, RA Busuttil, S Pattison, PJ Neeson, A Boussioutas 		World journal of gastroenterology : WJG 2016
Myeloid-derived suppressor cells and their role in pancreatic cancer
M Pergamo, G Miller 		Cancer Gene Therapy 2016
Neural innervation stimulates splenic TFF2 to arrest myeloid cell expansion and cancer
Z Dubeykovskaya, Y Si, X Chen, DL Worthley, BW Renz, AM Urbanska, Y Hayakawa, T Xu, CB Westphalen, A Dubeykovskiy, D Chen, RA Friedman, S Asfaha, K Nagar, Y Tailor, S Muthupalani, JG Fox, J Kitajewski, TC Wang 		Nature Communications 2016
A second chance for telomerase reverse transcriptase in anticancer immunotherapy
M Zanetti 		Nature Reviews Clinical Oncology 2016
The role of myeloid cells in cancer therapies
C Engblom, C Pfirschke, MJ Pittet 		Nature Reviews Cancer 2016
Neutrophils are Essential in Short Hairpin RNA of Indoleamine 2,3- Dioxygenase Mediated-antitumor Efficiency
KT Liu, YH Liu, HL Liu, IW Chong, MC Yen, PL Kuo 		Molecular Therapy - Nucleic Acids 2016
Overexpression of PIK3CA in murine head and neck epithelium drives tumor invasion and metastasis through PDK1 and enhanced TGFβ signaling
L Du, X Chen, Y Cao, L Lu, F Zhang, S Bornstein, Y Li, P Owens, S Malkoski, S Said, F Jin, M Kulesz-Martin, N Gross, XJ Wang, SL Lu 		Oncogene 2016
Utilizing cell-based therapeutics to overcome immune evasion in hematologic malignancies
C Sun, G Dotti, B Savoldo 		Blood 2016
A2A adenosine receptor antagonists to weaken the hypoxia-HIF-1α driven immunosuppression and improve immunotherapies of cancer
SM Hatfield, M Sitkovsky 		Current Opinion in Pharmacology 2016
Doxorubicin resistant cancer cells activate myeloid-derived suppressor cells by releasing PGE2
Y Rong, CH Yuan, Z Qu, H Zhou, Q Guan, N Yang, XH Leng, L Bu, K Wu, FB Wang 		Scientific Reports 2016
Oncogenic mTOR signalling recruits myeloid-derived suppressor cells to promote tumour initiation
T Welte, IS Kim, L Tian, X Gao, H Wang, J Li, XB Holdman, JI Herschkowitz, A Pond, G Xie, S Kurley, T Nguyen, L Liao, LE Dobrolecki, L Pang, Q Mo, DP Edwards, S Huang, L Xin, J Xu, Y Li, MT Lewis, T Wang, TF Westbrook, JM Rosen, XH Zhang 		Nature Cell Biology 2016
Myeloid-derived suppressor cells in gliomas
A Gieryng, B Kaminska 		WSPOLCZESNA ONKOL 2016
Granulocyte macrophage colony-stimulating factor predicts postoperative recurrence of clear-cell renal cell carcinoma
Y Chang, L Xu, L Zhou, Q Fu, Z Liu, Y Yang, Z Lin, J Xu 		Oncotarget 2016
Considerations for successful cancer immunotherapy in aged hosts: Ageing and cancer immunotherapy
V Hurez, ÁS Padrón, RS Svatek, TJ Curiel 		Clinical & Experimental Immunology 2016
Colonic macrophage polarization in homeostasis, inflammation, and cancer
RA Isidro, CB Appleyard 		AJP Gastrointestinal and Liver Physiology 2016
Expansion and functions of myeloid-derived suppressor cells in the tumor microenvironment
P Qu, L Wang, PC Lin 		Cancer Letters 2016
The Role of Myeloid-Derived Suppressor Cells (MDSC) in Cancer Progression
V Umansky, C Blattner, C Gebhardt, J Utikal 		Human vaccines 2016
Oncolytic viruses as immunotherapy: progress and remaining challenges
L Aurelian 		OncoTargets and therapy 2016
NK Cells, Tumor Cell Transition, and Tumor Progression in Solid Malignancies: New Hints for NK-Based Immunotherapy?
C Cantoni, L Huergo-Zapico, M Parodi, M Pedrazzi, MC Mingari, A Moretta, B Sparatore, S Gonzalez, D Olive, C Bottino, R Castriconi, M Vitale 		Journal of Immunology Research 2016
Depletion of FAP+ cells reduces immunosuppressive cells and improves metabolism and functions CD8+T cells within tumors
Y Zhang, HC Ertl 		Oncotarget 2016
Neutrophils in cancer: neutral no more
SB Coffelt, MD Wellenstein, KE de Visser 		Nature Reviews Cancer 2016
Murine mesothelioma induces locally-proliferating IL-10 + TNF-α + CD206 − CX3CR1 + M3 macrophages that can be selectively depleted by chemotherapy or immunotherapy
C Jackaman, TL Yeoh, ML Acuil, JK Gardner, DJ Nelson 		OncoImmunology 2016
Sunitinib: the antiangiogenic effects and beyond
Z Hao, I Sadek 		OncoTargets and therapy 2016
Resistance to anticancer immunity in cancer patients: potential strategies to reverse resistance
B Bonavida, S Chouaib 		Annals of Oncology 2016
Targeting Immune Regulatory Networks to Counteract Immune Suppression in Cancer
C Camisaschi, V Vallacchi, E Vergani, M Tazzari, S Ferro, A Tuccitto, O Kuchuk, E Shahaj, R Sulsenti, C Castelli, M Rodolfo, L Rivoltini, V Huber 		Human vaccines 2016
Epigenetics in myeloid derived suppressor cells: a sheathed sword towards cancer
C Zhang, S Wang, Y Liu, C Yang 		Oncotarget 2016
The Bone Microenvironment: a Fertile Soil for Tumor Growth
D Buenrostro, PL Mulcrone, P Owens, JA Sterling 		Current Osteoporosis Reports 2016
Ocular Immune Privilege and Transplantation
AW Taylor 		Frontiers in immunology 2016
Mutations Associated with Acquired Resistance to PD-1 Blockade in Melanoma
JM Zaretsky, A Garcia-Diaz, DS Shin, H Escuin-Ordinas, W Hugo, S Hu-Lieskovan, DY Torrejon, G Abril-Rodriguez, S Sandoval, L Barthly, J Saco, BH Moreno, R Mezzadra, B Chmielowski, K Ruchalski, IP Shintaku, PJ Sanchez, C Puig-Saus, G Cherry, E Seja, X Kong, J Pang, B Berent-Maoz, B Comin-Anduix, TG Graeber, PC Tumeh, TN Schumacher, RS Lo, A Ribas 		New England Journal of Medicine 2016
Myeloid-derived suppressor cells correlate with patient outcomes in hepatic arterial infusion chemotherapy for hepatocellular carcinoma
E Mizukoshi, T Yamashita, K Arai, T Terashima, M Kitahara, H Nakagawa, N Iida, K Fushimi, S Kaneko 		Cancer Immunology, Immunotherapy 2016
Lectin-type oxidized LDL receptor-1 distinguishes population of human polymorphonuclear myeloid-derived suppressor cells in cancer patients
T Condamine, GA Dominguez, JI Youn, AV Kossenkov, S Mony, K Alicea-Torres, E Tcyganov, A Hashimoto, Y Nefedova, C Lin, S Partlova, A Garfall, DT Vogl, X Xu, SC Knight, G Malietzis, GH Lee, E Eruslanov, SM Albelda, X Wang, JL Mehta, M Bewtra, A Rustgi, N Hockstein, R Witt, G Masters, B Nam, D Smirnov, MA Sepulveda, DI Gabrilovich 		Science Immunology 2016
Anti-Cancer Properties of the Naturally Occurring Aphrodisiacs: Icariin and Its Derivatives
HL Tan, KG Chan, P Pusparajah, S Saokaew, A Duangjai, LH Lee, BH Goh 		Frontiers in pharmacology 2016
Dysregulation of TGFβ1 Activity in Cancer and Its Influence on the Quality of Anti-Tumor Immunity
K Hargadon 		Journal of Clinical Medicine 2016
ΔPK oncolytic activity includes modulation of the tumour cell milieu
A Colunga, B Li, L Aurelian, D Bollino 		Journal of General Virology 2016
Regulation of Natural Killer Cell Function by STAT3
NA Cacalano 		Frontiers in immunology 2016
Mesenchymal Stem Cells and Myeloid Derived Suppressor Cells: Common Traits in Immune Regulation
IL Vladimirovna, E Sosunova, A Nikolaev, T Nenasheva 		Journal of Immunology Research 2016
Exosomes miR-126a released from MDSC induced by DOX treatment promotes lung metastasis
Z Deng, Y Rong, Y Teng, X Zhuang, A Samykutty, J Mu, L Zhang, P Cao, J Yan, D Miller, HG Zhang 		Oncogene 2016
The oncolytic virus ΔPK has multimodal anti-tumor activity
L Aurelian, D Bollino, A Colunga, M Flajnik 		Pathogens and Disease 2016
SCHLAFEN 5 expression correlates with intestinal metaplasia that progresses to gastric cancer
OC Nápoles, AC Tsao, JM Sanz-Anquela, N Sala, C Bonet, ML Pardo, L Ding, O Simo, M Saqui-Salces, VP Blanco, CA Gonzalez, JL Merchant 		Journal of Gastroenterology 2016
Finasteride Enhances the Generation of Human Myeloid-Derived Suppressor Cells by Up-Regulating the COX2/PGE2 Pathway
S Zhang, K Wu, Y Liu, Y Lin, X Zhang, J Zhou, H Zhang, T Pan, Y Fu, L Yang 		PloS one 2016
Colonization of xenograft tumors by oncolytic vaccinia virus (VACV) results in enhanced tumor killing due to the involvement of myeloid cells
MO Kilinc, K Ehrig, M Pessian, BR Minev, AA Szalay 		Journal of Translational Medicine 2016
The expression profiles and regulation of PD-L1 in tumor-induced myeloid-derived suppressor cells
C Lu, PS Redd, JR Lee, N Savage, K Liu 		OncoImmunology 2016
Increased Levels of Circulating and Tumor-Infiltrating Granulocytic Myeloid Cells in Colorectal Cancer Patients
SM Toor, AS Khaja, HE Salhat, O Bekdache, J Kanbar, M Jaloudi, E Elkord 		Frontiers in immunology 2016
PD-L1+MDSCs are increased in HCC patients and induced by soluble factor in the tumor microenvironment
T Iwata, Y Kondo, O Kimura, T Morosawa, Y Fujisaka, T Umetsu, T Kogure, J Inoue, Y Nakagome, T Shimosegawa 		Scientific Reports 2016
Pseudomonas aeruginosa Airway Infection Recruits and Modulates Neutrophilic Myeloid-Derived Suppressor Cells
HH Öz, B Zhou, P Voss, M Carevic, C Schroth, N Frey, N Rieber, A Hector, D Hartl 		Frontiers in Cellular and Infection Microbiology 2016
Immature myeloid cells in the tumor microenvironment: Implications for immunotherapy
N Kamran, M Chandran, PR Lowenstein, MG Castro 		Clinical Immunology 2016
Myeloid-derived suppressor cell, arginase-1, IL-17 and cl-CD95L: an explosive cocktail in lupus?
RJ Flynn, P Legembre 		Annals of translational medicine 2016
Lymphocyte-mediated Immune Regulation in Health and Disease: The Treg and γδ T Cell Co-conspiracy
KK Payne 		Immunological Investigations 2016
Sunitinib enhances the antitumor responses of agonistic CD40-antibody by reducing MDSCs and synergistically improving endothelial activation and T-cell recruitment
L Hooren, M Georganaki, H Huang, SM Mangsbo, A Dimberg 		Oncotarget 2016
Mesenchymal stromal cells (MSCs) and colorectal cancer: a troublesome twosome for the anti-tumour immune response?
G OMalley, M Heijltjes, AM Houston, S Rani, T Ritter, LJ Egan, AE Ryan 		Oncotarget 2016
Monocytic myeloid-derived suppressor cells as a potent suppressor of tumor immunity in non-small cell lung cancer
K Pogoda, M Pyszniak, P Rybojad, J Tabarkiewicz 		Oncology Letters 2016
DNA Methylation-Derived Neutrophil-to-Lymphocyte Ratio: An Epigenetic Tool to Explore Cancer Inflammation and Outcomes
DC Koestler, J Usset, BC Christensen, CJ Marsit, MR Karagas, KT Kelsey, JK Wiencke 		Cancer epidemiology, biomarkers & prevention 2016
Humanized Mouse Xenograft Models: Narrowing the Tumor–Microenvironment Gap
JJ Morton, G Bird, Y Refaeli, A Jimeno 		Cancer research 2016
Surface Glycoproteins of Exosomes Shed by Myeloid-Derived Suppressor Cells Contribute to Function
Chauhan S, Danielson S, Clements V, Edwards N, Ostrand-Rosenberg S, Fenselau C 		Journal of Proteome Research 2016
Activated T cells sustain myeloid-derived suppressor cell-mediated immune suppression.
Pinton L, Solito S, Damuzzo V, Francescato S, Pozzuoli A, Berizzi A, Mocellin S, Rossi CR, Bronte V, Mandruzzato S 		Oncotarget 2016
Tumor-induced myeloid deviation: when myeloid-derived suppressor cells meet tumor-associated macrophages
Stefano Ugel, Francesco De Sanctis, Susanna Mandruzzato, Vincenzo Bronte 		Journal of Clinical Investigation 2015
Cancer Immunotherapy: harnessing the immune system to battle cancer
Yiping Yang 		Journal of Clinical Investigation 2015
Mesothelioma response to carbon nanotubes is associated with an early and selective accumulation of immunosuppressive monocytic cells
F Huaux, VU de Bousies, MA Parent, M Orsi, F Uwambayinema, R Devosse, S Ibouraadaten, Y Yakoub, N Panin, M Palmai-Pallag, P der Bruggen, C Bailly, R Marega, E Marbaix, D Lison 		Particle and Fibre Toxicology 2015
Cancer Immunotherapy: Strategies for Personalization and Combinatorial Approaches
V Sathyanarayanan, SS Neelapu 		Molecular Oncology 2015
Immunosuppressive cells in tumor immune escape and metastasis
Y Liu, X Cao 		Journal of Molecular Medicine 2015
Myeloid cells in the tumor microenvironment: Role of adenosine
S Morello, A Pinto, C Blandizzi, L Antonioli 		OncoImmunology 2015
Placental immune editing switch (PIES): learning about immunomodulatory pathways from a unique case report
MH Bronchud, F Tresserra, W Xu, S Warren, M Cusido, B Zantop, AC Zenclussen, A Cesano 		Oncotarget 2015
Pulmonary surfactant: an immunological perspective
ZC Chroneos, Z Sever-Chroneos, VL Shepherd 		Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2009

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