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Citations to this article

Myeloid-derived suppressor cells in the tumor microenvironment: expect the unexpected
Douglas Marvel, Dmitry I. Gabrilovich
Douglas Marvel, Dmitry I. Gabrilovich
Published July 13, 2015
Citation Information: J Clin Invest. 2015;125(9):3356-3364. https://doi.org/10.1172/JCI80005.
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Review Series Article has an altmetric score of 25

Myeloid-derived suppressor cells in the tumor microenvironment: expect the unexpected

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Abstract

Our understanding of the role of myeloid-derived suppressor cells (MDSCs) in cancer is becoming increasingly complex. In addition to their eponymous role in suppressing immune responses, they directly support tumor growth, differentiation, and metastasis in a number of ways that are only now beginning to be appreciated. It is because of this increasingly complex role that these cells may become an important factor in the treatment of human cancer. In this Review, we discuss the most pertinent and controversial issues of MDSC biology and their role in promoting cancer progression and highlight how these cells may be used in the clinic, both as prognostic factors and as therapeutic targets.

Authors

Douglas Marvel, Dmitry I. Gabrilovich

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Total citations by year

Year: 2025 2024 2023 2022 2021 2020 2019 2018 2017 2016 2015 2009 Total
Citations: 18 34 51 65 80 77 62 71 79 63 7 1 608
Citation information
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