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Citations to this article

Breast cancer — one term, many entities?
Nicholas R. Bertos, Morag Park
Nicholas R. Bertos, Morag Park
Published October 3, 2011
Citation Information: J Clin Invest. 2011;121(10):3789-3796. https://doi.org/10.1172/JCI57100.
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Review Series Article has an altmetric score of 13

Breast cancer — one term, many entities?

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Abstract

Breast cancer, rather than constituting a monolithic entity, comprises heterogeneous tumors with different clinical characteristics, disease courses, and responses to specific treatments. Tumor-intrinsic features, including classical histological and immunopathological classifications as well as more recently described molecular subtypes, separate breast tumors into multiple groups. Tumor-extrinsic features, including microenvironmental configuration, also have prognostic significance and further expand the list of tumor-defining variables. A better understanding of the features underlying heterogeneity, as well as of the mechanisms and consequences of their interactions, is essential to improve targeting of existing therapies and to develop novel agents addressing specific combinations of features.

Authors

Nicholas R. Bertos, Morag Park

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Total citations by year

Year: 2024 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 Total
Citations: 5 5 11 4 2 9 5 6 14 6 12 16 8 1 1 1 106
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Oncotarget 2010
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Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2009

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