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A β_IV-spectrin/CaMKII signaling complex is essential for membrane excitability in mice

Thomas J. Hund, … , Mark E. Anderson, Peter J. Mohler

Thomas J. Hund, … , Mark E. Anderson, Peter J. Mohler

Published September 27, 2010
Citation Information: J Clin Invest. 2010;120(10):3508-3519. https://doi.org/10.1172/JCI43621.

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Title and authors	Publication	Year
βIV spectrin abundancy, cellular distribution and sensitivity to AKT/GSK3 regulation in schizophrenia. Di Re J, Marini M, Hussain SI, Singh AK, Venkatesh A, Alshammari MA, Alshammari TK, Hamoud AA, Imami AS, Haghighijoo Z, Fularcyzk N, Stertz L, Hawes D, Mosebarger A, Jernigan J, Chaljub C, Nehme R, Walss-Bass C, Schulmann A, Vawter MP, McCullumsmith R, Damoiseaux RD, Limon A, Labate D, Wells MF, Laezza F	Molecular psychiatry	2025
Phosphoproteomic profiling identifies DNMT1 as a key substrate of beta IV spectrin-dependent ERK/MAPK signaling in suppressing angiogenesis. Flores PC, Ahmed T, Podgorski J, Ortiz HR, Langlais PR, Mythreye K, Lee NY	Biochemical and Biophysical Research Communications	2024
Empagliflozin inhibits increased Na influx in atrial cardiomyocytes of patients with HFpEF Trum M, Riechel J, Schollmeier E, Lebek S, Hegner P, Reuthner K, Heers S, Keller K, Wester M, Klatt S, Hamdani N, Provaznik Z, Schmid C, Maier L, Arzt M, Wagner S	Cardiovascular Research	2024
Phosphorylation of cardiac sodium channel at Ser571 anticipates manifestations of the aging myopathy Pizzo E, Cervantes DO, Ketkar H, Ripa V, Nassal DM, Buck B, Parambath SP, Di Stefano V, Singh K, Thompson CI, Mohler PJ, Hund TJ, Jacobson JT, Jain S, Rota M	American Journal of Physiology - Heart and Circulatory Physiology	2024
Heparan Sulfates Regulate Axonal Excitability and Context Generalization through Ca2+/Calmodulin-Dependent Protein Kinase II Song I, Kuznetsova T, Baidoe-Ansah D, Mirzapourdelavar H, Senkov O, Hayani H, Mironov A, Kaushik R, Druzin M, Johansson S, Dityatev A	Cells	2023
Spectrins: molecular organizers and targets of neurological disorders. Lorenzo DN, Edwards RJ, Slavutsky AL	Nature reviews. Neuroscience	2023
Chronic Propafenone Application Increases Functional K(IR)2.1 Expression In Vitro. Li E, Kool W, Woolschot L, van der Heyden MAG	Pharmaceuticals (Basel, Switzerland)	2023
Feedback contributions to excitation–contraction coupling in native functioning striated muscle Salvage SC, Dulhunty AF, Jeevaratnam K, Jackson AP, Huang CL	Philosophical Transactions of the Royal Society B: Biological Sciences	2023
Endothelial tip/stalk cell selection requires BMP9-induced βIV-spectrin expression during sprouting angiogenesis Ahmed T, Ramonett A, Kwak EA, Kumar S, Flores PC, Ortiz HR, Langlais PR, Hund TJ, Mythreye K, Lee NY	Molecular biology of the cell	2023
Microtubule plus-end tracking proteins: novel modulators of cardiac sodium channels and arrhythmogenesis. Marchal GA, Galjart N, Portero V, Remme CA	Cardiovascular Research	2023
βIV-Spectrin in Cardiac Fibroblasts: Implications for Fibrosis and Therapeutic Targeting in Cardiac Diseases. Comment on Nassal et al. Spectrin-Based Regulation of Cardiac Fibroblast Cell-Cell Communication. Cells 2023, 12, 748. Xiang W, Zhou N, Li L, Chen F, Li L, Wang Y	Cells	2023
Genomic and Non-Genomic Regulatory Mechanisms of the Cardiac Sodium Channel in Cardiac Arrhythmias H Daimi, E Lozano-Velasco, A Aranega, D Franco	International journal of molecular sciences	2022
βIV-spectrin as a stalk cell-intrinsic regulator of VEGF signaling E Kwak, C Pan, A Ramonett, S Kumar, P Cruz-Flores, T Ahmed, H Ortiz, J Lochhead, N Ellis, G Mouneimne, T Georgieva, Y Lee, T Vanderah, T Largent-Milnes, P Mohler, T Hund, P Langlais, K Mythreye, N Lee	Nature Communications	2022
Subcellular trafficking and endocytic recycling of KATP channels Yang HQ, Echeverry FA, ElSheikh A, Gando I, Anez Arredondo S, Samper N, Cardozo T, Delmar M, Shyng SL, Coetzee WA	AJP Cell Physiology	2022
Ventricular voltage‐gated ion channels: Detection, characteristics, mechanisms, and drug safety evaluation L Chen, Y He, X Wang, J Ge, H Li	Clinical and Translational Medicine	2021
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Regulation of Cardiac Conduction and Arrhythmias by Ankyrin/Spectrin-Based Macromolecular Complexes D Nassal, J Yu, D Min, C Lane, R Shaheen, D Gratz, TJ Hund	Journal of Cardiovascular Development and Disease	2021
Cardioprotection by SGLT2 Inhibitors—Does It All Come Down to Na+? M Trum, J Riechel, S Wagner	International journal of molecular sciences	2021
Proteomic and functional mapping of cardiac NaV1.5 channel phosphorylation sites M Lorenzini, S Burel, A Lesage, E Wagner, C Charrière, PM Chevillard, B Evrard, D Maloney, KM Ruff, RV Pappu, S Wagner, JM Nerbonne, JR Silva, RR Townsend, LS Maier, C Marionneau	The Journal of General Physiology	2021
Phospho-ablation of cardiac sodium channel Nav1.5 mitigates susceptibility to atrial fibrillation and improves glucose homeostasis under conditions of diet-induced obesity RS Dewal, A Greer-Short, C Lane, S Nirengi, PA Manzano, D Hernández-Saavedra, KR Wright, D Nassal, LA Baer, PJ Mohler, TJ Hund, KI Stanford	International Journal of Obesity	2021
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Ca2+/calmodulin kinase II–dependent regulation of βIV-spectrin modulates cardiac fibroblast gene expression, proliferation, and contractility DM Nassal, NJ Patel, SD Unudurthi, R Shaheen, J Yu, PJ Mohler, TJ Hund	The Journal of biological chemistry	2021
A Rare Variant of ANK3 Is Associated With Intracranial Aneurysm J Liu, X Liao, J Zhou, B Li, L Xu, S Liu, Y Li, D Yuan, C Hu, W Jiang, J Yan	Frontiers in neurology	2021
Ca2+-dependent modulation of voltage-gated myocyte sodium channels SC Salvage, ZF Habib, HR Matthews, AP Jackson, CL Huang	Biochemical Society Transactions	2021
CaMKII in Regulation of Cell Death During Myocardial Reperfusion Injury Y Yang, K Jiang, X Liu, M Qin, Y Xiang	Frontiers in Molecular Biosciences	2021
Calbindin regulates Kv4.1 trafficking and excitability in dentate granule cells via CaMKII-dependent phosphorylation KR Kim, HJ Jeong, Y Kim, SY Lee, Y Kim, HJ Kim, SH Lee, H Cho, JS Kang, WK Ho	Experimental & molecular medicine	2021
Giant ankyrin-G regulates cardiac function O Cavus, J Williams, H Musa, ME Refaey, D Gratz, R Shaheen, NA Schwieterman, S Koenig, S Antwi-Boasiako, LJ Young, X Xu, M Han, LE Wold, TJ Hund, PJ Mohler, EA Bradley	The Journal of biological chemistry	2021
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Heritable arrhythmia syndromes associated with abnormal cardiac sodium channel function: ionic and non-ionic mechanisms MR Rivaud, M Delmar, CA Remme	Cardiovascular Research	2020
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Challenges and Opportunities for Therapeutic Targeting of Calmodulin Kinase II in Heart D Nassal, D Gratz, TJ Hund	Frontiers in pharmacology	2020
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Ankyrin-G mediates targeting of both Na+ and KATP channels to the rat cardiac intercalated disc HQ Yang, M Pérez-Hernández, J Sanchez-Alonso, A Shevchuk, J Gorelik, E Rothenberg, M Delmar, WA Coetzee	eLife	2020
β spectrin-dependent and domain specific mechanisms for Na+ channel clustering CH Liu, R Seo, TS Ho, M Stankewich, PJ Mohler, TJ Hund, JL Noebels, MN Rasband	eLife	2020
Emerging therapeutic targets for cardiac arrhythmias: Role of STAT3 in regulating cardiac fibroblast function NJ Patel, DM Nassal, D Gratz, TJ Hund	Expert Opinion on Therapeutic Targets	2020
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βIV-spectrin/STAT3 complex regulates fibroblast phenotype, fibrosis and cardiac function Nehal J. Patel, Drew M. Nassal, Amara Greer-Short, Sathya Unudurthi, Benjamin W Scandling, Daniel Gratz, Xianyao Xu, Anuradha Kalyanasundaram, Vadim V. Fedorov, Federica Accornero, Peter J. Mohler, Keith J Gooch, Thomas J Hund	JCI Insight	2019
Protein Phosphatase 2A Regulates Cardiac Na + Channels ME Refaey, H Musa, NP Murphy, E Lubbers, M Skaf, M Han, O Cavus, SN Koenig, MJ Wallace, D Gratz, E Bradley, KM Alsina, XH Wehrens, TJ Hund, PJ Mohler	Circulation research	2019
Conduction in the right and left ventricle is differentially regulated by protein kinases and phosphatases: implications for arrhythmogenesis AV Zaitsev, NS Torres, KM Cawley, AD Sabry, JS Warren, M Warren	American journal of physiology. Heart and circulatory physiology	2019
Calmodulin kinase II regulates atrial myocyte late sodium current, calcium handling, and atrial arrhythmia A Greer-Short, H Musa, KM Alsina, L Ni, TA Word, JO Reynolds, D Gratz, C Lane, M El-Refaey, S Unudurthi, M Skaf, N Li, VV Fedorov, XH Wehrens, PJ Mohler, TJ Hund	Heart rhythm : the official journal of the Heart Rhythm Society	2019
Gene Therapy for Catecholaminergic Polymorphic Ventricular Tachycardia by Inhibition of Ca 2+ /Calmodulin-Dependent Kinase II VJ Bezzerides, A Caballero, S Wang, Y Ai, RJ Hylind, F Lu, DA Heims-Waldron, KD Chambers, D Zhang, DJ Abrams, WT Pu	Circulation	2019
Axonal Spectrins: Nanoscale Organization, Functional Domains and Spectrinopathies CH Liu, MN Rasband	Frontiers in cellular neuroscience	2019
Supporting the heart: Functions of the cardiomyocyte's non-sarcomeric cytoskeleton KM Grimes, V Prasad, JW McNamara	Journal of Molecular and Cellular Cardiology	2019
Defining new mechanistic roles for αII spectrin in cardiac function ER Lubbers, NP Murphy, H Musa, CY Huang, R Gupta, MV Price, M Han, G Daoud, D Gratz, ME Refaey, X Xu, NK Hoeflinger, EL Friel, P Lancione, MJ Wallace, O Cavus, SL Simmons, JL Williams, M Skaf, SN Koenig, PM Janssen, MN Rasband, TJ Hund, PJ Mohler	The Journal of biological chemistry	2019
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Neurodevelopmental mutation of giant ankyrin-G disrupts a core mechanism for axon initial segment assembly R Yang, KK Walder-Christensen, S Lalani, H Yan, ID García-Prieto, S Álvarez, A Fernández-Jaén, L Speltz, YH Jiang, V Bennett	Proceedings of the National Academy of Sciences	2019
STAT3: A link between CaMKII/βIV-spectrin and maladaptive remodeling? Mohit Hulsurkar, Ann Quick, Xander H.T. Wehrens	Journal of Clinical Investigation	2018
Oxidative Stress Creates a Unique, CaMKII Mediated Substrate for Atrial Fibrillation in Heart Failure Shin Yoo, Gary Aistrup, Yohannes Shiferaw, Jason Ng, Peter J. Mohler, Thomas J Hund, Trent A. Waugh, Suzanne Browne, Georg Gussak, Mehul Gilani, Bradley P. Knight, Rod Passman, Jeffrey Goldberger, J. Andrew Wasserstrom, Rishi Arora	JCI Insight	2018
betaIV-spectrin regulates STAT3 targeting to tune cardiac response to pressure overload Sathya Unudurthi, Drew M Nassal, Amara Greer-Short, Nehal J. Patel, Taylor Howard, Xianyao Xu, Birce Onal, Tony Satroplus, Deborah Y Hong, Cemantha M Lane, Alyssa Dalic, Sara N Koenig, Adam C. Lehnig, Lisa A. Baer, Hassan Musa, Kristin I. Stanford, Sakima A Smith, Peter J. Mohler, Thomas J. Hund	Journal of Clinical Investigation	2018
Phosphorylation of cardiac voltage‐gated sodium channel: Potential players with multiple dimensions SM Iqbal, R LemmensGruber	Acta physiologica (Oxford, England)	2018
CaMKII-dependent late sodium current increases electrical dispersion and arrhythmia in ischemia/reperfusion T Howard, A Greer-Short, T Satroplus, N Patel, D Nassal, PJ Mohler, TJ Hund	American journal of physiology. Heart and circulatory physiology	2018
β-adrenergic regulation of late Na+ current during cardiac action potential is mediated by both PKA and CaMKII B Hegyi, T Bányász, LT Izu, L Belardinelli, DM Bers, Y Chen-Izu	Journal of Molecular and Cellular Cardiology	2018
Primary Effect of SERCA2a Gene Transfer on Conduction Reserve in Chronic Myocardial Infarction LJ Motloch, M Cacheux, K Ishikawa, C Xie, J Hu, J Aguero, KM Fish, RJ Hajjar, FG Akar	Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease	2018
Cardiac CaMKII activation promotes rapid translocation to its extra-dyadic targets BM Wood, M Simon, S Galice, CC Alim, M Ferrero, NN Pinna, DM Bers, J Bossuyt	Journal of Molecular and Cellular Cardiology	2018
Voltage-Gated Sodium Channel β1/β1B Subunits Regulate Cardiac Physiology and Pathophysiology N Edokobi, LL Isom	Frontiers in physiology	2018
Novel Mechanistic Roles for Ankyrin-G in Cardiac Remodeling and Heart Failure MA Makara, J Curran, ER Lubbers, NP Murphy, SC Little, H Musa, SA Smith, SD Unudurthi, MV Rajaram, PM Janssen, PA Boyden, EA Bradley, TJ Hund, PJ Mohler	JACC: Basic to Translational Science	2018
Arrhythmogenic Substrates for Atrial Fibrillation in Obesity ER Lubbers, MV Price, PJ Mohler	Frontiers in physiology	2018
The Effect of Ca2+, Lobe-Specificity, and CaMKII on CaM Binding to NaV1.1 J Li, Z Yu, J Xu, R Feng, Q Gao, T Boczek, J Liu, Z Li, Q Wang, M Lei, J Gong, H Hu, E Minobe, HL Ji, M Kameyama, F Guo	International journal of molecular sciences	2018
Type 2 Diabetes Leads to Axon Initial Segment Shortening in db/db Mice LM Yermakov, DE Drouet, RB Griggs, KM Elased, K Susuki	Frontiers in cellular neuroscience	2018
Localized Myosin II Activity Regulates Assembly and Plasticity of the Axon Initial Segment SL Berger, A Leo-Macias, S Yuen, L Khatri, S Pfennig, Y Zhang, E Agullo-Pascual, G Caillol, MS Zhu, E Rothenberg, CV Melendez-Vasquez, M Delmar, C Leterrier, JL Salzer	Neuron	2018
The Axon Initial Segment: An Updated Viewpoint C Leterrier	The Journal of neuroscience : the official journal of the Society for Neuroscience	2018
Potential new mechanisms of pro-arrhythmia in arrhythmogenic cardiomyopathy: focus on calcium sensitive pathways CJ van Opbergen, M Delmar, TA van Veen	Netherlands Heart Journal	2017
Blockade of CaMKII depresses conduction preferentially in the right ventricular outflow tract and promotes ischemic ventricular fibrillation in the rabbit heart M Warren, KJ Sciuto, TG Taylor, V Garg, NS Torres, J Shibayama, KW Spitzer, AV Zaitsev	American journal of physiology. Heart and circulatory physiology	2017
C-terminal phosphorylation of Na V 1.5 impairs FGF13-dependent regulation of channel inactivation S Burel, FC Coyan, M Lorenzini, MR Meyer, CF Lichti, JH Brown, G Loussouarn, F Charpentier, JM Nerbonne, RR Townsend, LS Maier, C Marionneau	The Journal of biological chemistry	2017
Ca 2+ /calmodulin-dependent kinase II-dependent regulation of atrial myocyte late Na + current, Ca 2+ cycling, and excitability: a mathematical modeling study B Onal, D Gratz, TJ Hund	American journal of physiology. Heart and circulatory physiology	2017
Obscure functions: the location–function relationship of obscurins HR Manring, OA Carter, MA Ackermann	Biophysical Reviews	2017
Axonal Membranes and Their Domains: Assembly and Function of the Axon Initial Segment and Node of Ranvier AD Nelson, PM Jenkins	Frontiers in cellular neuroscience	2017
A recessive mutation in beta-IV-spectrin (SPTBN4) associates with congenital myopathy, neuropathy, and central deafness E Knierim, E Gill, F Seifert, S Morales-Gonzalez, SD Unudurthi, TJ Hund, W Stenzel, M Schuelke	Human Genetics	2017
Mild Traumatic Brain Injury Evokes Pyramidal Neuron Axon Initial Segment Plasticity and Diffuse Presynaptic Inhibitory Terminal Loss M Vascak, J Sun, M Baer, KM Jacobs, JT Povlishock	Frontiers in cellular neuroscience	2017
Autoinhibition of ankyrin-B/G membrane target bindings by intrinsically disordered segments from the tail regions K Chen, J Li, C Wang, Z Wei, M Zhang	eLife	2017
CaMKII modulates sodium current in neurons from epileptic Scn2a mutant mice CH Thompson, NA Hawkins, JA Kearney, AL George	Proceedings of the National Academy of Sciences	2017
Ankyrins and Spectrins in Cardiovascular Biology and Disease MM el Refaey, PJ Mohler	Frontiers in physiology	2017
Late sodium current associated cardiac electrophysiological and mechanical dysfunction S Yu, G Li, CL Huang, M Lei, L Wu	Pflügers Archiv - European Journal of Physiology	2017
Non-canonical heterogeneous cellular distribution and co-localization of CaMKIIα and CaMKIIβ in the spinal superficial dorsal horn M Larsson	Brain structure & function	2017
Spectrin-based pathways underlying electrical and mechanical dysfunction in cardiac disease SD Unudurthi, A Greer-Short, N Patel, D Nassal, TJ Hund	Expert Review of Cardiovascular Therapy	2017
Murine Electrophysiological Models of Cardiac Arrhythmogenesis CL Huang	Physiological reviews	2016
Atrial remodelling in atrial fibrillation: CaMKII as a nodal proarrhythmic signal OO Mesubi, ME Anderson	Cardiovascular Research	2016
Vascular CaMKII: heart and brain in your arteries F Toussaint, C Charbel, BG Allen, J Ledoux	American journal of physiology. Cell physiology	2016
Neuronal Na+ Channels Are Integral Components of Pro-Arrhythmic Na+/Ca2+ Signaling Nanodomain That Promotes Cardiac Arrhythmias During β-Adrenergic Stimulation PB Radwański, HT Ho, R Veeraraghavan, L Brunello, B Liu, AE Belevych, SD Unudurthi, MA Makara, SG Priori, P Volpe, AA Armoundas, WH Dillmann, BC Knollmann, PJ Mohler, TJ Hund, S Györke	JACC: Basic to Translational Science	2016
Atrial-specific pathways for control of intracellular signaling and myocyte function TJ Hund, PJ Mohler	Journal of Clinical Investigation	2016
Quantifying Drug-Induced Nanomechanics and Mechanical Effects to Single Cardiomyocytes for Optimal Drug Administration To Minimize Cardiotoxicity T Yue, KH Park, BE Reese, H Zhu, S Lyon, J Ma, PJ Mohler, M Zhang	Langmuir	2016
Complexity of cardiac ion channel macromolecular complexes PJ Mohler, H Abriel	Cardiovascular Research	2016
Dysfunction of the β 2 -spectrin-based pathway in human heart failure SA Smith, LD Hughes, CF Kline, AN Kempton, LE Dorn, J Curran, M Makara, TR Webb, P Wright, N Voigt, PF Binkley, PM Janssen, A Kilic, CA Carnes, D Dobrev, MN Rasband, TJ Hund, PJ Mohler	American journal of physiology. Heart and circulatory physiology	2016
Two‐Pore K + Channel TREK‐1 Regulates Sinoatrial Node Membrane Excitability SD Unudurthi, X Wu, L Qian, F Amari, B Onal, N Li, MA Makara, SA Smith, J Snyder, VV Fedorov, V Coppola, ME Anderson, PJ Mohler, TJ Hund	Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease	2016
Fine-mapping, novel loci identification, and SNP association transferability in a genome-wide association study of QRS duration in African Americans DS Evans, CL Avery, MA Nalls, G Li, J Barnard, EN Smith, T Tanaka, AM Butler, SG Buxbaum, A Alonso, DE Arking, GS Berenson, JC Bis, S Buyske, CL Carty, W Chen, MK Chung, SR Cummings, R Deo, CB Eaton, ER Fox, SR Heckbert, G Heiss, LA Hindorff, WC Hsueh, A Isaacs, Y Jamshidi, KF Kerr, F Liu, Y Liu, KK Lohman, JW Magnani, JF Maher, R Mehra, YA Meng, SK Musani, C Newton-Cheh, KE North, BM Psaty, S Redline, JI Rotter, RB Schnabel, NJ Schork, RV Shohet, AB Singleton, JD Smith, EZ Soliman, SR Srinivasan, HA Taylor, DR van Wagoner, JG Wilson, T Young, ZM Zhang, AB Zonderman, MK Evans, L Ferrucci, SS Murray, GJ Tranah, EA Whitsel, AP Reiner, N Sotoodehnia	Human Molecular Genetics	2016
Cardiac Na Channels: Structure to Function. DeMarco KR, Clancy CE	Current topics in membranes	2016
Protein assemblies of sodium and inward rectifier potassium channels control cardiac excitability and arrhythmogenesis BC Willis, D Ponce-Balbuena, J Jalife	American journal of physiology. Heart and circulatory physiology	2015
Na + channel function, regulation, structure, trafficking and sequestration: Na + channel function, structure and trafficking Y Chen-Izu, RM Shaw, GS Pitt, V Yarov-Yarovoy, JT Sack, H Abriel, RW Aldrich, L Belardinelli, MB Cannell, WA Catterall, WJ Chazin, N Chiamvimonvat, I Deschenes, E Grandi, TJ Hund, LT Izu, LS Maier, VA Maltsev, C Marionneau, PJ Mohler, S Rajamani, RL Rasmusson, EA Sobie, CE Clancy, DM Bers	The Journal of Physiology	2015
Role of Sodium and Calcium Dysregulation in Tachyarrhythmias in Sudden Cardiac Death S Wagner, LS Maier, DM Bers	Circulation research	2015
Voltage-Gated Sodium Channel Phosphorylation at Ser571 Regulates Late Current, Arrhythmia, and Cardiac Function In VivoCLINICAL PERSPECTIVE P Glynn, H Musa, X Wu, SD Unudurthi, S Little, L Qian, PJ Wright, PB Radwanski, S Gyorke, PJ Mohler, TJ Hund	Circulation	2015
Late I Na in the Heart: Physiology, Pathology, and Pathways JC Makielski, JW Kyle	Circulation	2015
Counteracting Protein Kinase Activity in the Heart: The Multiple Roles of Protein Phosphatases S Weber, S Meyer-Roxlau, M Wagner, D Dobrev, A El-Armouche	Frontiers in pharmacology	2015
CaMKII Phosphorylation of Na V 1.5: Novel in Vitro Sites Identified by Mass Spectrometry and Reduced S516 Phosphorylation in Human Heart Failure AW Herren, DM Weber, RR Rigor, KB Margulies, BS Phinney, DM Bers	Journal of Proteome Research	2015
Quantitative Proteomics Reveals Protein–Protein Interactions with Fibroblast Growth Factor 12 as a Component of the Voltage-Gated Sodium Channel 1.2 (Nav1.2) Macromolecular Complex in Mammalian Brain NC Wildburger, SR Ali, WC Hsu, AS Shavkunov, MN Nenov, CF Lichti, RD LeDuc, E Mostovenko, NI Panova-Elektronova, MR Emmett, CL Nilsson, F Laezza	Molecular & cellular proteomics : MCP	2015
Protein phosphatase 2A regulatory subunit B56 limits phosphatase activity in the heart SC Little, J Curran, MA Makara, CF Kline, HT Ho, Z Xu, X Wu, I Polina, H Musa, AM Meadows, CA Carnes, BJ Biesiadecki, JP Davis, N Weisleder, S Gyorke, XH Wehrens, TJ Hund, PJ Mohler	Science signaling	2015
Exon Organization and Novel Alternative Splicing of Ank3 in Mouse Heart G Yamankurt, HC Wu, M McCarthy, SR Cunha, E Buratti	PloS one	2015
Calcium-Activated Potassium Channels at Nodes of Ranvier Secure Axonal Spike Propagation J Gründemann, BA Clark	Cell Reports	2015
Deletion of FoxO1 Leads to Shortening of QRS by Increasing Na+ Channel Activity through Enhanced Expression of both Cardiac NaV1.5 and β3 Subunit B Cai, N Wang, W Mao, T You, Y Lu, X Li, B Ye, F Li, H Xu	Journal of Molecular and Cellular Cardiology	2014
CaMKII-dependent regulation of cardiac Na(+) homeostasis E Grandi, AW Herren	Frontiers in pharmacology	2014
Handbook of Experimental Pharmacology C Antzelevitch, V Nesterenko, JC Shryock, S Rajamani, Y Song, L Belardinelli	Handbook of experimental pharmacology	2014
Tubulin polymerization disrupts cardiac -adrenergic regulation of late INa N Dybkova, S Wagner, J Backs, TJ Hund, PJ Mohler, T Sowa, VO Nikolaev, LS Maier	Cardiovascular Research	2014
Toward a hierarchy of mechanisms in CaMKII-mediated arrhythmia KP Vincent, AD McCulloch, AG Edwards	Frontiers in pharmacology	2014
Role of CaMKII in cardiac arrhythmias TJ Hund, PJ Mohler	Trends in Cardiovascular Medicine	2014
A novel computational model of mouse myocyte electrophysiology to assess the synergy between Na + loading and CaMKII: CaMKII-Na + -Ca 2+ -CaMKII feedback in cardiac myocytes S Morotti, AG Edwards, AD McCulloch, DM Bers, E Grandi	The Journal of Physiology	2014
Ankyrin-G Coordinates Intercalated Disc Signaling Platform to Regulate Cardiac Excitability In Vivo MA Makara, J Curran, SC Little, H Musa, I Polina, SA Smith, PJ Wright, SD Unudurthi, J Snyder, V Bennett, TJ Hund, PJ Mohler	Circulation research	2014
Nav Channel Complex Heterogeneity: New Targets for the Treatment of Arrhythmia? TJ Hund, PJ Mohler	Circulation	2014
CaMKII inhibitors: from research tools to therapeutic agents P Pellicena, H Schulman	Frontiers in pharmacology	2014
Axon initial segments: diverse and dynamic neuronal compartments T Yoshimura, MN Rasband	Current Opinion in Neurobiology	2014
IV-Spectrin regulates TREK-1 membrane targeting in the heart TJ Hund, JS Snyder, X Wu, P Glynn, OM Koval, B Onal, ND Leymaster, SD Unudurthi, J Curran, C Camardo, PJ Wright, PF Binkley, ME Anderson, PJ Mohler	Cardiovascular Research	2014
Assembly of the cardiac intercalated disk during pre- and postnatal development of the human heart A Vreeker, L Stuijvenberg, TJ Hund, PJ Mohler, PG Nikkels, TA van Veen	PloS one	2014
Modeling CaMKII in cardiac physiology: from molecule to tissue B Onal, SD Unudurthi, TJ Hund	Frontiers in pharmacology	2014
Role of the Axonal Initial Segment in Psychiatric Disorders: Function, Dysfunction, and Intervention WC Hsu, CL Nilsson, F Laezza	Frontiers in Psychiatry	2014
Diseases Caused by Mutations in Nav1.5 Interacting Proteins JW Kyle, JC Makielski	Cardiac Electrophysiology Clinics	2014
EHD3-Dependent Endosome Pathway Regulates Cardiac Membrane Excitability and Physiology J Curran, MA Makara, SC Little, H Musa, B Liu, X Wu, I Polina, JS Alecusan, P Wright, J Li, GE Billman, PA Boyden, S Gyorke, H Band, TJ Hund, PJ Mohler	Circulation research	2014
The arrhythmogenic consequences of increasing late INa in the cardiomyocyte JC Shryock, Y Song, S Rajamani, C Antzelevitch, L Belardinelli	Cardiovascular Research	2013
The promise of CaMKII inhibition for heart disease: preventing heart failure and arrhythmias BD Westenbrink, AG Edwards, AD McCulloch, JH Brown	Expert Opinion on Therapeutic Targets	2013
Mechanisms of Altered Ca 2+ Handling in Heart Failure M Luo, ME Anderson	Circulation research	2013
Redox Regulation of Sodium and Calcium Handling S Wagner, AG Rokita, ME Anderson, LS Maier	Antioxidants & Redox Signaling	2013
Role of late sodium current as a potential arrhythmogenic mechanism in the progression of pressure-induced heart disease K Toischer, N Hartmann, S Wagner, TH Fischer, J Herting, BC Danner, CM Sag, TJ Hund, PJ Mohler, L Belardinelli, G Hasenfuss, LS Maier, S Sossalla	Journal of Molecular and Cellular Cardiology	2013
Post-translational modifications of the cardiac Na channel: contribution of CaMKII-dependent phosphorylation to acquired arrhythmias AW Herren, DM Bers, E Grandi	American journal of physiology. Heart and circulatory physiology	2013
A Memory Molecule, Ca2+/Calmodulin-Dependent Protein Kinase II and Redox Stress; Key Factors for Arrhythmias in a Diseased Heart YH Song	Korean Circulation Journal	2013
Molecular determinants for cardiovascular TRPC6 channel regulation by Ca 2+ /calmodulin-dependent kinase II: Molecular mechanism for CaMKII-mediated TRPC6 regulation J Shi, N Geshi, S Takahashi, S Kiyonaka, J Ichikawa, Y Hu, Y Mori, Y Ito, R Inoue	The Journal of Physiology	2013
Channelopathies from mutations in the cardiac sodium channel protein complex GS Adsit, R Vaidyanathan, CM Galler, JW Kyle, JC Makielski	Journal of Molecular and Cellular Cardiology	2013
L-type calcium channels play a critical role in maintaining lens transparency by regulating phosphorylation of aquaporin-0 and myosin light chain and expression of connexins R Maddala, T Nagendran, GG de Ridder, KL Schey, PV Rao	PloS one	2013
Deletion of the last five C-terminal amino acid residues of connexin43 leads to lethal ventricular arrhythmias in mice without affecting coupling via gap junction channels I Lübkemeier, RP Requardt, X Lin, P Sasse, R Andrié, JW Schrickel, H Chkourko, FF Bukauskas, JS Kim, M Frank, D Malan, J Zhang, A Wirth, R Dobrowolski, PJ Mohler, S Offermanns, BK Fleischmann, M Delmar, K Willecke	Basic Research in Cardiology	2013
Integrative Biological Analysis For Neuropsychopharmacology MR Emmett, RA Kroes, JR Moskal, CA Conrad, W Priebe, F Laezza, A Meyer-Baese, CL Nilsson	Neuropsychopharmacology	2013
DNA methylation map of mouse and human brain identifies target genes in Alzheimer's disease JV Sanchez-Mut, E Aso, N Panayotis, I Lott, M Dierssen, A Rabano, RG Urdinguio, AF Fernandez, A Astudillo, JI Martin-Subero, B Balint, MF Fraga, A Gomez, C Gurnot, JC Roux, J Avila, TK Hensch, I Ferrer, M Esteller	Brain	2013
Ankyrin-G participates in INa remodeling in myocytes from the border zones of infarcted canine heart W Dun, JS Lowe, P Wright, TJ Hund, PJ Mohler, PA Boyden	PloS one	2013
βIV-Spectrin and CaMKII facilitate Kir6.2 regulation in pancreatic beta cells CF Kline, PJ Wright, OM Koval, EJ Zmuda, BL Johnson, ME Anderson, T Hai, TJ Hund, PJ Mohler	Proceedings of the National Academy of Sciences	2013
Calcineurin signaling mediates activity-dependent relocation of the axon initial segment MD Evans, RP Sammons, S Lebron, AS Dumitrescu, TB Watkins, VN Uebele, JJ Renger, MS Grubb	The Journal of neuroscience : the official journal of the Society for Neuroscience	2013
Ankyrin-B protein in heart failure: identification of a new component of metazoan cardioprotection F Kashef, J Li, P Wright, J Snyder, F Suliman, A Kilic, RS Higgins, ME Anderson, PF Binkley, TJ Hund, PJ Mohler	The Journal of biological chemistry	2012
Na + Channel I–II Loop Mediates Parallel Genetic and Phosphorylation-Dependent Gating Changes DM Bers, AW Herren	Circulation	2012
Ca 2+ /Calmodulin-Dependent Protein Kinase II–Based Regulation of Voltage-Gated Na + Channel in Cardiac Disease OM Koval, JS Snyder, RM Wolf, RE Pavlovicz, P Glynn, J Curran, ND Leymaster, W Dun, PJ Wright, N Cardona, L Qian, CC Mitchell, PA Boyden, PF Binkley, C Li, ME Anderson, PJ Mohler, TJ Hund	Circulation	2012
Calmodulin-dependent protein kinase II: linking heart failure and arrhythmias PD Swaminathan, A Purohit, TJ Hund, ME Anderson	Circulation research	2012
New Therapeutic Targets in Cardiology: Arrhythmias and Ca 2+ /Calmodulin-Dependent Kinase II (CaMKII) AG Rokita, ME Anderson	Circulation	2012
Mass Spectrometry-Based Identification of Native Cardiac Nav1.5 Channel α Subunit Phosphorylation Sites C Marionneau, CF Lichti, P Lindenbaum, F Charpentier, JM Nerbonne, RR Townsend, J Mérot	Journal of Proteome Research	2012
Ca2+/calmodulin-dependent protein kinase II (CaMKII) regulates cardiac sodium channel NaV1.5 gating by multiple phosphorylation sites NM Ashpole, AW Herren, KS Ginsburg, JD Brogan, DE Johnson, TR Cummins, DM Bers, A Hudmon	The Journal of biological chemistry	2012
Remodeling of the cardiac sodium channel, connexin 43, and plakoglobin at the intercalated disk in patients with arrhythmogenic cardiomyopathy M Noorman, S Hakim, E Kessler, JA Groeneweg, MG Cox, A Asimaki, HV van Rijen, L Stuijvenberg, H Chkourko, MA van der Heyden, MA Vos, N Jonge, JJ van der Smagt, D Dooijes, A Vink, RA de Weger, A Varro, JM de Bakker, JE Saffitz, TJ Hund, PJ Mohler, M Delmar, RN Hauer, TA van Veen	Heart Rhythm	2012
IκBα is not required for axon initial segment assembly SA Buffington, JM Sobotzik, C Schultz, MN Rasband	Molecular and Cellular Neuroscience	2012
Simulation and Mechanistic Investigation of the Arrhythmogenic Role of the Late Sodium Current in Human Heart Failure B Trenor, K Cardona, JF Gomez, S Rajamani, JM Ferrero, L Belardinelli, J Saiz	PloS one	2012
Defects in Cytoskeletal Signaling Pathways, Arrhythmia, and Sudden Cardiac Death S Smith, J Curran, TJ Hund, PJ Mohler	Frontiers in physiology	2012
Age-Related Intraneuronal Elevation of αII-Spectrin Breakdown Product SBDP120 in Rodent Forebrain Accelerates in 3×Tg-AD Mice Y Cai, HX Zhu, JM Li, XG Luo, PR Patrylo, GM Rose, J Streeter, R Hayes, KK Wang, XX Yan, A Jeromin	PloS one	2012
Sodium current deficit and arrhythmogenesis in a murine model of plakophilin-2 haploinsufficiency M Cerrone, M Noorman, X Lin, H Chkourko, FX Liang, R der Nagel, T Hund, W Birchmeier, P Mohler, TA van Veen, HV van Rijen, M Delmar	Cardiovascular Research	2012
CaMKII inhibition rescues proarrhythmic phenotypes in the model of human ankyrin-B syndrome S DeGrande, D Nixon, O Koval, JW Curran, P Wright, Q Wang, F Kashef, D Chiang, N Li, XH Wehrens, ME Anderson, TJ Hund, PJ Mohler	Heart rhythm : the official journal of the Heart Rhythm Society	2012
Cysteine 70 of ankyrin-G is S-palmitoylated and is required for function of ankyrin-G in membrane domain assembly M He, P Jenkins, V Bennett	The Journal of biological chemistry	2012
CaMKII in the Cardiovascular System: Sensing Redox States JR Erickson, BJ He, IM Grumbach, ME Anderson	Physiological reviews	2011
CaMKII in myocardial hypertrophy and heart failure ME Anderson, JH Brown, DM Bers	Journal of Molecular and Cellular Cardiology	2011
Fluorescence Resonance Energy Transfer–Based Sensor Camui Provides New Insight Into Mechanisms of Calcium/Calmodulin-Dependent Protein Kinase II Activation in Intact Cardiomyocytes JR Erickson, R Patel, A Ferguson, J Bossuyt, DM Bers	Circulation research	2011
Beyond membrane channelopathies: alternative mechanisms underlying complex human disease KD Boudoulas, PJ Mohler	Acta Pharmacologica Sinica	2011
Coordinating electrical activity of the heart: ankyrin polypeptides in human cardiac disease J Curran, PJ Mohler	Expert Opinion on Therapeutic Targets	2011
Compartmentation of membrane processes and nucleotide dynamics in diffusion-restricted cardiac cell microenvironment AE Alekseev, S Reyes, VA Selivanov, PP Dzeja, A Terzic	Journal of Molecular and Cellular Cardiology	2011
Reactive Oxygen Species–Activated Ca/Calmodulin Kinase IIδ Is Required for Late INa Augmentation Leading to Cellular Na and Ca Overload S Wagner, HM Ruff, SL Weber, S Bellmann, T Sowa, T Schulte, ME Anderson, E Grandi, DM Bers, J Backs, L Belardinelli, LS Maier	Circulation research	2011
Short- and long-term plasticity at the axon initial segment MS Grubb, Y Shu, H Kuba, MN Rasband, VC Wimmer, KJ Bender	The Journal of neuroscience : the official journal of the Society for Neuroscience	2011
Di-rectifying Tau S Jha, MN Rasband	The EMBO Journal	2011
Spectrin-based skeleton as an actor in cell signaling B Machnicka, R Grochowalska, DM Bogusławska, AF Sikorski, MC Lecomte	Cellular and Molecular Life Sciences	2011
Schwann cell spectrins modulate peripheral nerve myelination K Susuki, AR Raphael, Y Ogawa, MC Stankewich, E Peles, WS Talbot, MN Rasband	Proceedings of the National Academy of Sciences	2011
Ankyrin-based Cellular Pathways for Cardiac Ion Channel and Transporter Targeting and Regulation SR Cunha, PJ Mohler	Seminars in Cell & Developmental Biology	2011
Interactions Between Ankyrin-G, Plakophilin-2, and Connexin43 at the Cardiac Intercalated Disc PY Sato, W Coombs, X Lin, O Nekrasova, KJ Green, LL Isom, SM Taffet, M Delmar	Circulation research	2011
Location, location, regulation: a novel role for beta spectrin in the heart Robert S. Kass, Kevin Sampson	Journal of Clinical Investigation	2010
Pulmonary surfactant: an immunological perspective ZC Chroneos, Z Sever-Chroneos, VL Shepherd	Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology	2009

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