Todd E. Golde
Title and authors | Publication | Year |
---|---|---|
Alzheimer’s disease – the journey of a healthy brain into organ failure
T Golde |
Molecular Neurodegeneration | 2022 |
Disease-Modifying Therapies for Alzheimer’s Disease: More Questions than Answers
Golde TE |
Neurotherapeutics | 2022 |
Functional chicken-liver hydrolysates ameliorate insulin resistance and cognitive decline in streptozotocin-induced diabetic mice.
Yeh WY, Lin YL, Yang WY, Chou CH, Wu YS, Chen YC |
Poultry science | 2022 |
From Hybrids to New Scaffolds: The Latest Medicinal Chemistry Goals in Multi-target Directed Ligands for Alzheimer's Disease.
Alarcón-Espósito J, Mallea M, Rodríguez-Lavado J |
Current neuropharmacology | 2021 |
Can we learn lessons from the FDA’s approval of aducanumab?
KY Liu, R Howard |
Nature Reviews Neurology | 2021 |
Novel strategies for the fight of Alzheimer’s disease targeting amyloid-β protein
Y Xie, Y Wang, S Jiang, X Xiang, J Wang, L Ning |
Journal of Drug Targeting | 2021 |
γ-Secretase modulators exhibit selectivity for modulation of APP cleavage but inverse γ-secretase modulators do not
CB Lessard, E Rodriguez, TB Ladd, LM Minter, BA Osborne, L Miele, TE Golde, Y Ran |
Alzheimer's research & therapy | 2020 |
Isoquinolines from national herb Corydalis tomentella and neuroprotective effect against lipopolysaccharide-induced BV2 microglia cells
YM Wang, WZ Ming, H Liang, YJ Wang, YH Zhang, DL Meng |
Bioorganic chemistry | 2020 |
Alcohol consumption and cognitive function in elderly Japanese men
AT Siddiquee, A Kadota, A Fujiyoshi, N Miyagawa, Y Saito, H Suzuki, K Kondo, H Yamauchi, T Ito, H Segawa, I Tooyama, K Miura, H Ueshima |
Alcohol (Fayetteville, N.Y.) | 2020 |
3,3-Difluoro-3,4,5,6-tetrahydropyridin-2-amines: potent and permeable BACE-1 inhibitors
A Peschiulli, D Oehlrich, F Rombouts, A Vos, HJ Gijsen |
Bioorganic & Medicinal Chemistry Letters | 2020 |
Deficiency in BDNF/TrkB Neurotrophic Activity Stimulates δ-Secretase by Upregulating C/EBPβ in Alzheimer’s Disease
ZH Wang, J Xiang, X Liu, SP Yu, FP Manfredsson, IM Sandoval, S Wu, JZ Wang, K Ye |
Cell Reports | 2019 |
A Closer Look into the Role of Protein Tau in the Identification of Promising Therapeutic Targets for Alzheimer’s Disease
RI Khan, S Nirzhor, B Rashid |
Brain Sciences | 2018 |
Tramiprosate (Alzhemed) for Alzheimer's disease
Malouf R, Collins H |
The Cochrane Database of Systematic Reviews | 2018 |
Pathological Role of Peptidyl-Prolyl Isomerase Pin1 in the Disruption of Synaptic Plasticity in Alzheimer’s Disease
L Xu, Z Ren, FE Chow, R Tsai, T Liu, F Rizzolio, S Boffo, Y Xu, S Huang, CF Lippa, Y Gong |
Neural plasticity | 2017 |
Mouse Models for Drug Discovery
G Proetzel, MV Wiles |
Mouse Models for Drug Discovery | 2016 |
Mouse Models for Drug Discovery
G Proetzel, MV Wiles |
Mouse Models for Drug Discovery | 2016 |
Mouse Models for Drug Discovery
G Proetzel, MV Wiles |
Mouse Models for Drug Discovery | 2016 |
Mouse Models for Drug Discovery
G Proetzel, MV Wiles |
Mouse Models for Drug Discovery | 2016 |
Mouse Models for Drug Discovery
G Proetzel, MV Wiles |
Mouse Models for Drug Discovery | 2016 |
Mouse Models for Drug Discovery
G Proetzel, MV Wiles |
Mouse Models for Drug Discovery | 2016 |
In Vivo Detection of Amyloid Plaques by Gadolinium-Stained MRI Can Be Used to Demonstrate the Efficacy of an Anti-amyloid Immunotherapy
MD Santin, ME Vandenberghe, AS Herard, L Pradier, C Cohen, T Debeir, T Delzescaux, T Rooney, M Dhenain |
Frontiers in aging neuroscience | 2016 |
Versatility of the Curcumin Scaffold: Discovery of Potent and Balanced Dual BACE-1 and GSK-3β Inhibitors
RM di Martino, AD Simone, V Andrisano, P Bisignano, A Bisi, S Gobbi, A Rampa, R Fato, C Bergamini, DI Perez, A Martinez, G Bottegoni, A Cavalli, F Belluti |
Journal of Medicinal Chemistry | 2016 |
Resurrection of neurodegenerative diseases via stem cells
S Nagaraj |
Biomedical Research and Therapy | 2016 |
The Protective Effects of Icariin against the Homocysteine-Induced Neurotoxicity in the Primary Embryonic Cultures of Rat Cortical Neurons
XA Li, YS HO, L Chen, WL Hsiao |
Molecules (Basel, Switzerland) | 2016 |
Metal ion mediated transition from random coil to β-sheet and aggregation of Bri2-23, a natural inhibitor of Aβ aggregation
M Luczkowski, RD Ricco, M Stachura, S Potocki, L Hemmingsen, D Valensin |
Metallomics | 2015 |
Theta and alpha EEG frequency interplay in subjects with mild cognitive impairment: evidence from EEG, MRI, and SPECT brain modifications
DV Moretti |
Frontiers in aging neuroscience | 2015 |
Comparative studies using the Morris water maze to assess spatial memory deficits in two transgenic mouse models of Alzheimer's disease
SR Edwards, AS Hamlin, N Marks, EJ Coulson, MT Smith |
Clinical and Experimental Pharmacology and Physiology | 2014 |
Dose-Dependent Inhibition of BACE-1 by the Monoterpenoid 2,3,4,4-Tetramethyl-5-methylenecyclopent-2-enone in Cellular and Mouse Models of Alzheimer’s Disease
R Videira, P Castanheira, M Grãos, R Resende, L Salgueiro, C Faro, C Cavaleiro |
Journal of Natural Products | 2014 |
MER5101, a novel Aβ1-15:DT conjugate vaccine, generates a robust anti-Aβ antibody response and attenuates Aβ pathology and cognitive deficits in APPswe/PS1ΔE9 transgenic mice
B Liu, JL Frost, J Sun, H Fu, S Grimes, P Blackburn, CA Lemere |
The Journal of neuroscience : the official journal of the Society for Neuroscience | 2013 |
Nanoparticulate flurbiprofen reduces amyloid-β42 generation in an in vitro blood-brain barrier model
S Meister, I Zlatev, J Stab, D Docter, S Baches, RH Stauber, M Deutsch, R Schmidt, S Ropele, M Windisch, K Langer, S Wagner, H Briesen, S Weggen, CU Pietrzik |
Alzheimer's research & therapy | 2013 |
Suppressed Retinal Degeneration in Aged Wild Type and APPswe/PS1ΔE9 Mice by Bone Marrow Transplantation
Y Yang, C Shiao, JF Hemingway, NL Jorstad, BR Shalloway, R Chang, CD Keene, J Priller |
PloS one | 2013 |
The missing link in the amyloid cascade of Alzheimer’s disease – Metal ions
A Tiiman, P Palumaa, V Tõugu |
Neurochemistry International | 2013 |
Increase of theta frequency is associated with reduction in regional cerebral blood flow only in subjects with mild cognitive impairment with higher upper alpha/low alpha EEG frequency power ratio
DV Moretti, A Prestia, G Binetti, O Zanetti, GB Frisoni |
Frontiers in behavioral neuroscience | 2013 |
Relevance of Magnetic Resonance Imaging for Early Detection and Diagnosis of Alzheimer Disease
SJ Teipel, M Grothe, S Lista, N Toschi, FG Garaci, H Hampel |
Medical Clinics of North America | 2013 |
A necrodane monoterpenoid from Lavandula luisieri essential oil as a cell-permeable inhibitor of BACE-1, the β -secretase in Alzheimer's disease: Necrodane monoterpenoids from Lavandula luisieri inhibit β -secretase
R Videira, P Castanheira, M Grãos, L Salgueiro, C Faro, C Cavaleiro |
Flavour and Fragrance Journal | 2013 |
Neurodegeneration in Alzheimer Disease: Role of Amyloid Precursor Protein and Presenilin 1 Intracellular Signaling
M Nizzari, S Thellung, A Corsaro, V Villa, A Pagano, C Porcile, C Russo, T Florio |
Journal of Toxicology | 2012 |
A Plaque-Specific Antibody Clears Existing β-amyloid Plaques in Alzheimer's Disease Mice
RB DeMattos, J Lu, Y Tang, MM Racke, CA DeLong, JA Tzaferis, JT Hole, BM Forster, PC McDonnell, F Liu, RD Kinley, WH Jordan, ML Hutton |
Neuron | 2012 |
Chemical Biology, Molecular Mechanism and Clinical Perspective of γ-Secretase Modulators in Alzheimer’s Disease
B Bulic, J Ness, S Hahn, A Rennhack, T Jumpertz, S Weggen |
Current neuropharmacology | 2011 |
Apolipoprotein E: from lipid transport to neurobiology
PS Hauser, V Narayanaswami, RO Ryan |
Progress in Lipid Research | 2011 |
Pyridazine-derived γ-secretase modulators
Z Wan, A Hall, Y Jin, JN Xiang, E Yang, A Eatherton, B Smith, G Yang, H Yu, J Wang, L Ye, LF Lau, T Yang, W Mitchell, W Cai, X Zhang, Y Sang, Y Wang, Z Tong, Z Cheng, I Hussain, JD Elliott, Y Matsuoka |
Bioorganic & Medicinal Chemistry Letters | 2011 |
Alzheimer’s Disease: Current Status of Etiopathogenesis and Therapeutic Strategies
MI Kh, LA Kassem |
Pakistan Journal of Biological Sciences | 2011 |
Moderate alcohol consumption and cognitive risk
EJ Neafsey, MA Collins |
Neuropsychiatric Disease and Treatment | 2011 |
Cdk5: Multitasking between physiological and pathological conditions
JP Lopes, P Agostinho |
Progress in Neurobiology | 2011 |
Precolumn derivatization followed by liquid chromatographic separation and determination of tramiprosate in rat plasma by fluorescence detector: Application to pharmacokinetics
RN Rao, PK Maurya, DD Shinde, S Khalid |
Journal of Pharmaceutical and Biomedical Analysis | 2011 |
Epigenetic Aspects of Chronic Diseases
HI Roach, F Bronner, RO Oreffo |
2011 | |
Inhibition of phosphodiesterase-4 reverses memory deficits produced by Aβ25–35 or Aβ1–40 peptide in rats
YF Cheng, C Wang, HB Lin, YF Li, Y Huang, JP Xu, HT Zhang |
Psychopharmacology | 2010 |
Protein Misfolding Diseases
P Chakrabarty, P Das, TE Golde |
Protein Misfolding Diseases | 2010 |
Cochrane Database of Systematic Reviews: Reviews
N Shafiq, M Singh, S Kaur, P Khosla, S Malhotra, N Shafiq |
Cochrane Database of Systematic Reviews: Reviews | 2010 |
Alzheimer’s Disease: Fatty Acids We Eat may be Linked to a Specific Protection via Low-dose Aspirin
MF Pomponi, G Gambassi, M Pomponi, C Masullo |
Aging and disease | 2010 |
Blue Books of Neurology
H Wiendl, N Melzer, C Kleinschnitz, SG Meuth |
Blue Books of Neurology | 2010 |
An update on clinical proteomics in Alzheimer’s research
MA Korolainen, TA Nyman, T Aittokallio, T Pirttilä |
Journal of Neurochemistry | 2010 |
His-tag binding by antibody C706 mimics β-amyloid recognition
A Teplyakov, G Obmolova, G Canziani, Y Zhao, L Gutshall, SS Jung, GL Gilliland |
Journal of molecular recognition : JMR | 2010 |
Gelsolin as therapeutic target in Alzheimer's disease
E Carro |
Expert Opinion on Therapeutic Targets | 2010 |
fac -{Ru(CO) 3 } 2+ Selectively Targets the Histidine Residues of the β-Amyloid Peptide 1-28. Implications for New Alzheimer's Disease Treatments Based on Ruthenium Complexes
D Valensin, P Anzini, E Gaggelli, N Gaggelli, G Tamasi, R Cini, C Gabbiani, E Michelucci, L Messori, H Kozlowski, G Valensin |
Inorganic Chemistry | 2010 |
A small molecule inhibitor of signal peptide peptidase inhibits Plasmodium development in the liver and decreases malaria severity
I Parvanova, S Epiphanio, A Fauq, TE Golde, M Prudêncio, MM Mota |
PloS one | 2009 |
Modeling familial British and Danish dementia
HJ Garringer, J Murrell, L D’Adamio, B Ghetti, R Vidal |
Brain structure & function | 2009 |
Modular Synthesis of Heparan Sulfate Oligosaccharides for Structure−Activity Relationship Studies
S Arungundram, K Al-Mafraji, J Asong, FE Leach, IJ Amster, A Venot, JE Turnbull, GJ Boons |
Journal of the American Chemical Society | 2009 |
MCP-1 involvement in glial differentiation of neuroprogenitor cells through APP signaling
EG Vrotsos, PE Kolattukudy, K Sugaya |
Brain Research Bulletin | 2009 |
A Small Molecule Inhibitor of Signal Peptide Peptidase Inhibits Plasmodium Development in the Liver and Decreases Malaria Severity
I Parvanova, S Epiphanio, A Fauq, TE Golde, M Prudêncio, MM Mota, G Langsley |
PloS one | 2009 |
Pharmacogenomics in Drug Discovery and Development
Q Yan |
2008 | |
Pharmacogenomics in Drug Discovery and Development
Q Yan |
2008 | |
Pharmacogenomics in Drug Discovery and Development
Q Yan |
2008 | |
Pharmacogenomics in Drug Discovery and Development
Q Yan |
2008 | |
Pharmacogenomics in Drug Discovery and Development
Q Yan |
2008 | |
Pharmacogenomics in Drug Discovery and Development
Q Yan |
2008 | |
Pharmacogenomics in Drug Discovery and Development
Q Yan |
2008 | |
Pharmacogenomics in Drug Discovery and Development
Q Yan |
2008 | |
Pharmacogenomics in Drug Discovery and Development
Q Yan |
2008 | |
Restraining tumor necrosis factor-alpha by thalidomide prevents the Amyloid beta-induced impairment of recognition memory in mice
T Alkam, A Nitta, H Mizoguchi, K Saito, M Seshima, A Itoh, K Yamada, T Nabeshima |
Behavioural Brain Research | 2008 |
BRI2 (ITM2b) inhibits Abeta deposition in vivo
J Kim, VM Miller, Y Levites, KJ West, CW Zwizinski, BD Moore, FJ Troendle, M Bann, C Verbeeck, RW Price, L Smithson, L Sonoda, K Wagg, V Rangachari, F Zou, SG Younkin, N Graff-Radford, D Dickson, T Rosenberry, TE Golde |
The Journal of neuroscience : the official journal of the Society for Neuroscience | 2008 |
Apolipoprotein E and cholesterol in aging and disease in the brain
EP de Chaves, V Narayanaswami |
Future Lipidology | 2008 |
Early diagnosis and treatment of Alzheimer’s disease
PR Solomon, CA Murphy |
Expert Review of Neurotherapeutics | 2008 |
Aβ1–42 reduces synapse number and inhibits neurite outgrowth in primary cortical and hippocampal neurons: A quantitative analysis
NA Evans, L Facci, DE Owen, PE Soden, SA Burbidge, RK Prinjha, JC Richardson, SD Skaper |
Journal of Neuroscience Methods | 2008 |
Discovery of a novel series of Notch-sparing γ-secretase inhibitors
A Kreft, B Harrison, S Aschmies, K Atchison, D Casebier, DC Cole, G Diamantidis, J Ellingboe, D Hauze, Y Hu, D Huryn, M Jin, D Kubrak, P Lu, J Lundquist, C Mann, R Martone, W Moore, A Oganesian, A Porte, DR Riddell, J Sonnenberg-Reines, JR Stock, SC Sun, E Wagner, K Woller, Z Xu, H Zhou, JS Jacobsen |
Bioorganic & Medicinal Chemistry Letters | 2008 |
S14G-Humanin ameliorates Aβ25-35-induced behavioral deficits by reducing neuroinflammatory responses and apoptosis in mice
J Miao, W Zhang, R Yin, R Liu, C Su, G Lei, Z Li |
Neuropeptides | 2008 |
l-3-n-Butylphthalide ameliorates β-amyloid-induced neuronal toxicity in cultured neuronal cells
Y Peng, C Xing, CA Lemere, G Chen, L Wang, Y Feng, X Wang |
Neuroscience Letters | 2008 |
Soluble amyloid β oligomers may contribute to apoptosis of retinal ganglion cells in glaucoma
H Yin, L Chen, X Chen, X Liu |
Medical Hypotheses | 2008 |
Alzheimer's Disease Research: Progress and Promises
DD Christensen |
CNS Spectrums | 2008 |
5-Lipoxygenase gene disruption reduces amyloid-beta pathology in a mouse model of Alzheimer's disease
O Firuzi, J Zhuo, CM Chinnici, T Wisniewski, D Praticò |
The FASEB Journal | 2007 |
Dendrimeric Aβ1–15 is an effective immunogen in wildtype and APP-tg mice
TJ Seabrook, K Thomas, L Jiang, J Bloom, E Spooner, M Maier, G Bitan, CA Lemere |
Neurobiology of Aging | 2007 |
Changing the course of Alzheimer's disease: anti-amyloid disease-modifying treatments on the horizon
DD Christensen |
Primary care companion to the Journal of clinical psychiatry | 2007 |
Amyloid Precursor Protein and Presenilin Involvement in Cell Signaling
V Venezia, M Nizzari, P Carlo, A Corsaro, T Florio, C Russo |
Neurodegenerative Diseases | 2007 |
Targeting insulin-like growth factor-1 to treat Alzheimer's disease
I Torres-Aleman |
Expert Opinion on Therapeutic Targets | 2007 |
Looking for novel ways to treat the hallmarks of Alzheimer's disease
AJ Stewart, A Fox, BH Morimoto, I Gozes |
Expert Opinion on Investigational Drugs | 2007 |
Attenuated cytotoxicity but enhanced βfibril of a mutant amyloid β-peptide with a methionine to cysteine substitution
XL Dai, YX Sun, ZF Jiang |
FEBS Letters | 2007 |
The Pathogenesis of Alzheimer's Disease and the Role of Aβ42
TE Golde |
CNS Spectrums | 2007 |
Alzheimer's Disease: Progress in the Development of Anti-amyloid Disease-Modifying Therapies
DD Christensen |
CNS Spectrums | 2007 |
Amyloid Precursor Protein and Presenilin1 Interact with the Adaptor GRB2 and Modulate ERK 1,2 Signaling
M Nizzari, V Venezia, E Repetto, V Caorsi, R Magrassi, MC Gagliani, P Carlo, T Florio, G Schettini, C Tacchetti, T Russo, A Diaspro, C Russo |
The Journal of biological chemistry | 2007 |
Pharmacological Mechanisms in Alzheimer's Therapeutics
AC Cuello |
2007 | |
Insights into the mechanisms of action of anti-Abeta antibodies in Alzheimer's disease mouse models
Y Levites, LA Smithson, RW Price, RS Dakin, B Yuan, MR Sierks, J Kim, E McGowan, DK Reed, TL Rosenberry, P Das, TE Golde |
The FASEB Journal | 2006 |
Boosting with intranasal dendrimeric Aβ1–15 but not Aβ1–15 peptide leads to an effective immune response following a single injection of Aβ1–40/42 in APP-tg mice
TJ Seabrook, L Jiang, K Thomas, CA Lemere |
Journal of Neuroinflammation | 2006 |
Disease modifying therapy for AD?
TE Golde |
Journal of Neurochemistry | 2006 |
Inhibitors of Rho-kinase modulate amyloid-β (Aβ) secretion but lack selectivity for Aβ42
S Leuchtenberger, MP Kummer, T Kukar, E Czirr, N Teusch, SA Sagi, R Berdeaux, CU Pietrzik, TB Ladd, TE Golde, EH Koo, S Weggen |
Journal of Neurochemistry | 2006 |
Intracranial adeno-associated virus-mediated delivery of anti-pan amyloid beta, amyloid beta40, and amyloid beta42 single-chain variable fragments attenuates plaque pathology in amyloid precursor protein mice
Y Levites, K Jansen, LA Smithson, R Dakin, VM Holloway, P Das, TE Golde |
The Journal of neuroscience : the official journal of the Society for Neuroscience | 2006 |
Encyclopedia of Molecular Cell Biology and Molecular Medicine
E Beutler |
Encyclopedia of Molecular Cell Biology and Molecular Medicine | 2006 |
NEURODEGENERATIVE DISEASES: New Concepts of Pathogenesis and Their Therapeutic Implications
DM Skovronsky, VM Lee, JQ Trojanowski |
Annual Review of Pathology: Mechanisms of Disease | 2006 |
Plaques, Tangles, and Memory Loss in Mouse Models of Neurodegeneration
JL Eriksen, CG Janus |
Behavior Genetics | 2006 |
Structure-Based Organic Synthesis of Drug Prototypes: A Personal Odyssey
S Hanessian |
ChemMedChem | 2006 |
Longitudinal assessment of Alzheimer's β-amyloid plaque development in transgenic mice monitored by in vivo magnetic resonance microimaging
N Braakman, J Matysik, SG van Duinen, F Verbeek, R Schliebs, HJ de Groot, A Alia |
Journal of Magnetic Resonance Imaging | 2006 |
γ-Secretase Modulation with Aβ42-Lowering Nonsteroidal Anti-Inflammatory Drugs and Derived Compounds
E Czirr, S Weggen |
Neurodegenerative Diseases | 2006 |
Alzheimer Disease and Its Management: A Review
MK Samanta, B Wilson, K Santhi, KP Kumar, B Suresh |
American Journal of Therapeutics | 2006 |
Abeta42 neurotoxicity in primary co-cultures: effect of apoE isoform and Abeta conformation
AM Manelli, LC Bulfinch, PM Sullivan, MJ LaDu |
Neurobiology of Aging | 2006 |
Blockade of the insulin-like growth factor I receptor in the choroid plexus originates Alzheimer's-like neuropathology in rodents: New cues into the human disease?
E Carro, JL Trejo, C Spuch, D Bohl, JM Heard, I Torres-Aleman |
Neurobiology of Aging | 2006 |
Inverse relation between in vivo amyloid imaging load and cerebrospinal fluid Aβ 42 in humans
AM Fagan, MA Mintun, RH Mach, SY Lee, CS Dence, AR Shah, GN LaRossa, ML Spinner, WE Klunk, CA Mathis, ST DeKosky, JC Morris, DM Holtzman |
Annals of Neurology | 2006 |
Organofluorine Inhibitors of Amyloid Fibrillogenesis
M Török, M Abid, SC Mhadgut, B Török |
Biochemistry | 2006 |
The amyloid precursor protein and its network of interacting proteins: physiological and pathological implications
C Russo, V Venezia, E Repetto, M Nizzari, E Violani, P Carlo, G Schettini |
Brain research. Brain research reviews | 2005 |
Toward the Validation of Functional Neuroimaging as a Potential Biomarker for Alzheimer?s Disease: Implications for Drug Development
A Pupi, L Mosconi, FM Nobili, S Sorbi |
Molecular Imaging and Biology | 2005 |
Bringing amyloid into focus
TE Golde, BJ Bacskai |
Nature Biotechnology | 2005 |
STIGMATIZATION IN ALZHEIMER'S DISEASE RESEARCH ON AFRICAN AMERICAN ELDERS
EC Holston |
Issues in Mental Health Nursing | 2005 |
Intraneuronal Aβ accumulation and origin of plaques in Alzheimer's disease
GK Gouras, CG Almeida, RH Takahashi |
Neurobiology of Aging | 2005 |
Studies on the mechanism of action of a proline-rich polypeptide complex (PRP): Effect on the stage of cell differentiation
A Kubis, E Marcinkowska, M Janusz, J Lisowski |
Peptides | 2005 |
Synergistic amplification of β-amyloid- and interferon-γ-induced microglial neurotoxic response by the senile plaque component chromogranin A
G Twig, SA Graf, MA Messerli, PJ Smith, SH Yoo, OS Shirihai |
American journal of physiology. Cell physiology | 2005 |
Apoptotic Cell Death and Amyloid Precursor Protein Signaling in Neuroblastoma SH-SY5Y Cells
V Venezia, C Russo, E Repetto, M Nizzari, E Violani, P Carlo, B Marchetti, G Schettini |
Annals of the New York Academy of Sciences | 2004 |
BACE1 Overexpression Regulates Amyloid Precursor Protein Cleavage and Interaction with the ShcA Adapter
E Repetto, C Russo, V Venezia, M Nizzari, RM Nitsch, G Schettini |
Annals of the New York Academy of Sciences | 2004 |
Search Strategies Used by APP Transgenic Mice During Navigation in the Morris Water Maze
C Janus |
Learning & Memory | 2004 |
Apoptotic mechanisms in Alzheimer neurofibrillary degeneration: cause or effect?
DW Dickson |
Journal of Clinical Investigation | 2004 |
Genomic characterization of Alzheimer’s disease and genotype-related phenotypic analysis of biological markers in dementia
R Cacabelos |
Pharmacogenomics | 2004 |
Future directions in the treatment of Alzheimer’s disease
R Bullock |
Expert Opinion on Investigational Drugs | 2004 |
Neuroprotective effect of cannabidiol, a non-psychoactive component from Cannabis sativa, on beta-amyloid-induced toxicity in PC12 cells
T Iuvone, G Esposito, R Esposito, R Santamaria, MD Rosa, AA Izzo |
Journal of Neurochemistry | 2004 |
Insulin-like growth factor I and Alzheimer´s disease: therapeutic prospects?
E Carro, I Torres-Aleman |
Expert Review of Neurotherapeutics | 2004 |
Species-specific immune response to immunization with human versus rodent Aβ peptide
TJ Seabrook, JK Bloom, M Iglesias, ET Spooner, DM Walsh, CA Lemere |
Neurobiology of Aging | 2004 |
Neuroprotective strategies in Alzheimer’s disease
FM Longo, SM Massa |
NeuroRX | 2004 |
Inhibitors of beta-amyloid aggregation: still an issue of structure and function?
P Talaga |
Drug Discovery Today: Therapeutic Strategies | 2004 |
Oligomerization of Alzheimer's -Amyloid within Processes and Synapses of Cultured Neurons and Brain
RH Takahashi |
The Journal of neuroscience : the official journal of the Society for Neuroscience | 2004 |
Cognitive Enhancing Drugs
JJ Buccafusco |
2004 | |
Consistent Lowering of Abeta42 levels In Vitro and In Vivo by Commonly Used NSAIDs and Enantiomers of Flurbiprofen: Implications for Alzheimer’s Disease Therapy
Jason L. Eriksen, Sarah A. Sagi, Tawnya E. Smith, Sascha Weggen, Pritam Das, D.C. McLendon, Victor V. Ozols, Kevin W. Jessing, Kenton H. Zavitz, Edward H. Koo, Todd E. Golde |
Journal of Clinical Investigation | 2003 |
Series Introduction: Neurodegeneration: What is it and where are we?
S Przedborski, M Vila, V Jackson-Lewis |
Journal of Clinical Investigation | 2003 |
Alzheimer’s disease: from molecular pathogenesis to innovative therapies
E Scarpini, F Cogiamanian |
Expert Review of Neurotherapeutics | 2003 |
Antibodies against beta-amyloid slow cognitive decline in Alzheimer's disease
Christoph Hock, Uwe Konietzko, Johannes R Streffer, Jay Tracy, Andri Signorell, Britta Müller-Tillmanns, Ulrike Lemke, Katharina Henke, Eva Moritz, Esmeralda Garcia, M Axel Wollmer, Daniel Umbricht, Dominique J F de Quervain, Marc Hofmann, Alessia Maddalena, Andreas Papassotiropoulos, Roger M Nitsch |
Neuron | 2003 |
Partial Purification and Characterization of γ-Secretase from Post-mortem Human Brain
MR Farmery, LO Tjernberg, SE Pursglove, A Bergman, B Winblad, J Näslund |
The Journal of biological chemistry | 2003 |
Cholesterol: from heart attacks to Alzheimer's disease
RL Raffaï, KH Weisgraber |
Journal of lipid research | 2003 |
Kirk-Othmer Encyclopedia of Chemical Technology
GR Lenz, HG Schoepke, TC SPAULDING |
Kirk-Othmer Encyclopedia of Chemical Technology | 2000 |