Daytime-restricted parenteral feeding is associated with earlier oral intake in children following stem cell transplant
YunZu Michele Wang, … , John B. Hogenesch, Christopher E. Dandoy
YunZu Michele Wang, … , John B. Hogenesch, Christopher E. Dandoy
Published February 15, 2023
Citation Information: J Clin Invest. 2023;133(4):e167275. https://doi.org/10.1172/JCI167275.
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Research Letter Clinical trials Metabolism

Daytime-restricted parenteral feeding is associated with earlier oral intake in children following stem cell transplant

Abstract

Authors

YunZu Michele Wang, Cynthia B. Taggart, John F. Huber, Stella M. Davies, David F. Smith, John B. Hogenesch, Christopher E. Dandoy

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Figure 1

Daytime-restricted parenteral feeding is associated with earlier oral intake compared with continuous parenteral feeding in children after HSCT.

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Daytime-restricted parenteral feeding is associated with earlier oral in...
(A) Study timeline. (B) Study schema. (C) Glucose level in daytime-restricted nutrition (red) and continuous nutrition (blue) groups. The x axis represents days after HSCT. (D) Enteral calories in daytime-restricted (green) and continuous (white) groups. **P < 0.01. (E) i.v. nutrition calories in daytime-restricted (green) and continuous (unfilled) groups. (F) Duration of total parenteral nutrition (TPN) administration starting at day 0 in continuous (blue) and daytime-restricted (red) groups (P = 0.618). (G) Inpatient admission length for HSCT (P = 0.315). Data represent median ± interquartile range in C–G. Statistical significance was determined by Mann-Whitney U test for all analyses in D–G.