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Citations to this article

Impaired renal Na+ retention in the sgk1-knockout mouse
Peer Wulff, … , Florian Lang, Dietmar Kuhl
Peer Wulff, … , Florian Lang, Dietmar Kuhl
Published November 1, 2002
Citation Information: J Clin Invest. 2002;110(9):1263-1268. https://doi.org/10.1172/JCI15696.
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Article Nephrology

Impaired renal Na+ retention in the sgk1-knockout mouse

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Abstract

Research Article

Authors

Peer Wulff, Volker Vallon, Dan Yang Huang, Harald Völkl, Fang Yu, Kerstin Richter, Martina Jansen, Michaela Schlünz, Karin Klingel, Johannes Loffing, Gunther Kauselmann, Michael R. Bösl, Florian Lang, Dietmar Kuhl

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Year: 2025 2024 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 2006 2005 2004 2003 2002 Total
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ND Pietro, V Panel, S Hayes, A Bagattin, S Meruvu, A Pandolfi, L Hugendubler, G Fejes-Tóth, A Naray-Fejes-Tóth, E Mueller
Molecular Endocrinology 2010
Knockdown of Circadian Rhythm Gene Period 1 Dramatically Reduces Expression of the Renal Epithelial Sodium Channel
Michelle L. Gumz, Lisa R. Stow, I. Jeanette Lynch, Megan M. Greenlee, Alicia Rudin, Brian D. Cain, David R. Weaver and Charles S. Wingo
Journal of Clinical Investigation 2009
Akt2 and SGK3 are both determinants of postnatal hair follicle development
TM Mauro, JA McCormick, J Wang, KM Boini, L Ray, B Monks, MJ Birnbaum, F Lang, D Pearce
The FASEB Journal 2009
Pulmonary surfactant: an immunological perspective
ZC Chroneos, Z Sever-Chroneos, VL Shepherd
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2009
Regulated sodium transport in the renal connecting tubule (CNT) via the epithelial sodium channel (ENaC)
J Loffing, C Korbmacher
Pflügers Archiv - European Journal of Physiology 2009
Expression and phosphorylation of the Na+-Cl- cotransporter NCC in vivo is regulated by dietary salt, potassium, and SGK1
V Vallon, J Schroth, F Lang, D Kuhl, S Uchida
American journal of physiology. Renal physiology 2009
Rictor/TORC2 regulates Caenorhabditis elegans fat storage, body size, and development through sgk-1
KT Jones, ER Greer, D Pearce, K Ashrafi
PLoS Biology 2009
Regulation of a third conserved phosphorylation site in SGK1
W Chen, Y Chen, B Xu, YC Juang, S Stippec, Y Zhao, MH Cobb
The Journal of biological chemistry 2009
SGK1-sensitive renal tubular glucose reabsorption in diabetes
TF Ackermann, KM Boini, H Völkl, M Bhandaru, PM Bareiss, L Just, V Vallon, K Amann, D Kuhl, Y Feng, HP Hammes, F Lang
American journal of physiology. Renal physiology 2009
Stimulation of electrogenic intestinal dipeptide transport by the glucocorticoid dexamethasone
R Rexhepaj, A Rotte, DS Kempe, M Sopjani, M Föller, EM Gehring, M Bhandaru, I Gruner, AF Mack, I Rubio-Aliaga, AM Näßl, H Daniel, D Kuhl, F Lang
Pflügers Archiv - European Journal of Physiology 2009
Glucocorticoids can activate the α-ENaC gene promoter independently of SGK1
N McTavish, J Getty, A Burchell, SM Wilson
Biochemical Journal 2009
Sgk1 activates MDM2-dependent p53 degradation and affects cell proliferation, survival, and differentiation
R Amato, L D’Antona, G Porciatti, V Agosti, M Menniti, C Rinaldo, N Costa, E Bellacchio, S Mattarocci, G Fuiano, S Soddu, MG Paggi, F Lang, N Perrotti
Journal of Molecular Medicine 2009
Regulation of the Ca2+ Channel TRPV6 by the Kinases SGK1, PKB/Akt, and PIKfyve
M Sopjani, A Kunert, K Czarkowski, F Klaus, J Laufer, M Föller, F Lang
The Journal of Membrane Biology 2009
Regulation of epithelial sodium transport by promyelocytic leukemia zinc finger protein
A Náray-Fejes-Tóth, C Boyd, G Fejes-Tóth
American journal of physiology. Renal physiology 2008
A brain-specific SGK1 splice isoform regulates expression of ASIC1 in neurons
MF Arteaga, T Coric, C Straub, CM Canessa
Proceedings of the National Academy of Sciences 2008
SGK1 activity in Na+ absorbing airway epithelial cells monitored by assaying NDRG1-Thr346/356/366 phosphorylation
SK Inglis, M Gallacher, SG Brown, N McTavish, J Getty, EM Husband, JT Murray, SM Wilson
Pflügers Archiv - European Journal of Physiology 2008
Lack of the serum and glucocorticoid-inducible kinase SGK1 attenuates the volume retention after treatment with the PPARγ agonist pioglitazone
F Artunc, D Sandulache, O Nasir, KM Boini, B Friedrich, N Beier, E Dicks, S Pötzsch, K Klingel, K Amann, BL Blazer-Yost, W Scholz, T Risler, D Kuhl, F Lang
Pflügers Archiv - European Journal of Physiology 2008
SGK1 dependence of insulin induced hypokalemia
KM Boini, D Graf, D Kuhl, D Häussinger, F Lang
Pflügers Archiv - European Journal of Physiology 2008
Steroid hormone release as well as renal water and electrolyte excretion of mice expressing PKB/SGK-resistant GSK3
KM Boini, M Bhandaru, A Mack, F Lang
Pflügers Archiv - European Journal of Physiology 2008
Aldosterone-Stimulated SGK1 Activity Mediates Profibrotic Signaling in the Mesangium
Y Terada, H Kuwana, T Kobayashi, T Okado, N Suzuki, T Yoshimoto, Y Hirata, S Sasaki
Journal of the American Society of Nephrology : JASN 2008
Mutation of the PDK1 PH Domain Inhibits Protein Kinase B/Akt, Leading to Small Size and Insulin Resistance
JR Bayascas, S Wullschleger, K Sakamoto, JM García-Martínez, C Clacher, D Komander, DM van Aalten, KM Boini, F Lang, C Lipina, L Logie, C Sutherland, JA Chudek, JA van Diepen, PJ Voshol, JM Lucocq, DR Alessi
Molecular and cellular biology 2008
Aldosterone and glomerular podocyte injury
M Nagase, T Fujita
Clinical and Experimental Nephrology 2008
Aldosterone-induced SGK1 Phosphorylates AF9 and Relieves Dot1a-AF9-Mediated Transcriptional Repression of ENaCalpha
Wenzheng Zhang, Xuefeng Xia, Mary Rose Reisenauer, Timo Rieg, Florian Lang, Dietmar Kuhl,Volker Vallon, and Bruce C. Kone
Journal of Clinical Investigation 2007
Salt, sodium channels, and SGK1
David Pearce1 and Thomas R. Kleyman2
Journal of Clinical Investigation 2007
Role of the serum and glucocorticoid inducible kinase SGK1 in glucocorticoid stimulation of gastric acid secretion
C Sandu, F Artunc, F Grahammer, A Rotte, KM Boini, B Friedrich, D Sandulache, M Metzger, L Just, A Mack, T Skutella, R Rexhepaj, T Risler, P Wulff, D Kuhl, F Lang
Pflügers Archiv - European Journal of Physiology 2007
Genetics of salt-sensitive hypertension
P Strazzullo, F Galletti
Current Hypertension Reports 2007
Negative regulation of SEK1 signaling by serum- and glucocorticoid-inducible protein kinase 1
MJ Kim, JS Chae, KJ Kim, SG Hwang, KW Yoon, EK Kim, HJ Yun, JH Cho, J Kim, BW Kim, HC Kim, SS Kang, F Lang, SG Cho, EJ Choi
The EMBO Journal 2007
SGK1 survival through various lives may save us all
FC Luft
Journal of Molecular Medicine 2007
Crystal structure of the kinase domain of serum and glucocorticoid-regulated kinase 1 in complex with AMP-PNP
B Zhao, R Lehr, AM Smallwood, TF Ho, K Maley, T Randall, MS Head, KK Koretke, CG Schnackenberg
Protein Science 2007
Multiple Translational Isoforms Give Functional Specificity to Serum- and Glucocorticoid-induced Kinase 1
MF Arteaga, DA de la Rosa, JA Alvarez, CM Canessa, JS Gutkind
Molecular biology of the cell 2007
SGK1-dependent cardiac CTGF formation and fibrosis following DOCA treatment
V Vallon, AW Wyatt, K Klingel, DY Huang, A Hussain, S Berchtold, B Friedrich, F Grahammer, RS Belaiba, A Görlach, P Wulff, J Daut, ND Dalton, J Ross, U Flögel, J Schrader, H Osswald, R Kandolf, D Kuhl, F Lang
Journal of Molecular Medicine 2006
Renal Ca2+ handling in sgk1 knockout mice
D Sandulache, F Grahammer, F Artunc, G Henke, A Hussain, O Nasir, A Mack, B Friedrich, V Vallon, P Wulff, D Kuhl, M Palmada, F Lang
Pflügers Archiv - European Journal of Physiology 2006
Acute activation of NHE3 by dexamethasone correlates with activation of SGK1 and requires a functional glucocorticoid receptor
D Wang, H Zhang, F Lang, CC Yun
American journal of physiology. Cell physiology 2006
Mice heterozygous for beta-ENaC deletion have defective potassium excretion
XR Cao, PP Shi, RD Sigmund, RF Husted, CD Sigmund, RA Williamson, JB Stokes, B Yang
American journal of physiology. Renal physiology 2006
An amphipathic helix targets serum and glucocorticoid-induced kinase 1 to the endoplasmic reticulum-associated ubiquitin-conjugation machinery
MF Arteaga, L Wang, T Ravid, M Hochstrasser, CM Canessa
Proceedings of the National Academy of Sciences 2006
The N-terminus of the serum- and glucocorticoid-inducible kinase Sgk1 specifies mitochondrial localization and rapid turnover
A Engelsberg, F Kobelt, D Kuhl
Biochemical Journal 2006
SGK1 is not required for regulation of colonic ENaC activity
R Rexhepaj, F Artunc, F Grahammer, O Nasir, C Sandu, B Friedrich, D Kuhl, F Lang
Pflügers Archiv - European Journal of Physiology 2006
PI3-Kinase-dependent electrogenic intestinal transport of glucose and amino acids
R Rexhepaj, F Artunc, M Metzger, T Skutella, F Lang
Pflügers Archiv - European Journal of Physiology 2006
Additive regulation of GluR1 by stargazin and serum- and glucocorticoid-inducible kinase isoform SGK3
N Strutz-Seebohm, G Seebohm, G Korniychuk, R Baltaev, O Ureche, M Striegel, F Lang
Pflügers Archiv - European Journal of Physiology 2006
The serum- and glucocorticoid-induced kinase in DOCA–salt hypertension
FC Luft
Journal of Molecular Medicine 2006
Blunted DOCA/high salt induced albuminuria and renal tubulointerstitial damage in gene-targeted mice lacking SGK1
F Artunc, K Amann, O Nasir, B Friedrich, D Sandulache, N Jahovic, T Risler, V Vallon, P Wulff, D Kuhl, F Lang
Journal of Molecular Medicine 2006
Renal tubular transport and the genetic basis of hypertensive disease
F Lang, G Capasso, M Schwab, S Waldegger
Clinical and Experimental Nephrology 2005
Aldosterone acts via an ATP autocrine/paracrine system: the Edelman ATP hypothesis revisited
J Gorelik, Y Zhang, D Sánchez, A Shevchuk, G Frolenkov, M Lab, D Klenerman, C Edwards, Y Korchev
Proceedings of the National Academy of Sciences 2005
Activation of NHE3 by dexamethasone requires phosphorylation of NHE3 at Ser663 by SGK1
D Wang, H Sun, F Lang, CC Yun
American journal of physiology. Cell physiology 2005
KESTREL: a powerful method for identifying the physiological substrates of protein kinases
P Cohen, A Knebel
Biochemical Journal 2005
WNK1 activates SGK1 to regulate the epithelial sodium channel
B Xu, S Stippec, PY Chu, A Lazrak, XJ Li, BH Lee, JM English, B Ortega, CL Huang, MH Cobb
Proceedings of the National Academy of Sciences 2005
Impaired ability to increase water excretion in mice lacking the taurine transporter gene TAUT
DY Huang, KM Boini, PA Lang, F Grahammer, M Duszenko, B Heller-Stilb, U Warskulat, D Häussinger, F Lang, V Vallon
Pflügers Archiv - European Journal of Physiology 2005
Expression and insights on function of potassium channel TWIK-1 in mouse kidney
X Nie, I Arrighi, B Kaissling, I Pfaff, J Mann, J Barhanin, V Vallon
Pflügers Archiv - European Journal of Physiology 2005
Decreased intestinal glucose transport in the sgk3-knockout mouse
C Sandu, R Rexhepaj, F Grahammer, JA McCormick, G Henke, M Palmada, S Nammi, U Lang, M Metzger, L Just, T Skutella, K Dawson, J Wang, D Pearce, F Lang
Pflügers Archiv - European Journal of Physiology 2005
Targeted disruption of the protein kinase SGK3/CISK impairs postnatal hair follicle development
JA McCormick, Y Feng, K Dawson, MJ Behne, B Yu, J Wang, AW Wyatt, G Henke, F Grahammer, TM Mauro, F Lang, D Pearce
Molecular biology of the cell 2004
Functional consequences at the single-nephron level of the lack of adenosine A1 receptors and tubuloglomerular feedback in mice
V Vallon, K Richter, DY Huang, T Rieg, J Schnermann
Pflügers Archiv - European Journal of Physiology 2004
Exploitation of KESTREL to identify NDRG family members as physiological substrates for SGK1 and GSK3
JT Murray, DG Campbell, N Morrice, GC Auld, N Shpiro, R Marquez, M Peggie, J Bain, GB Bloomberg, F Grahammer, F Lang, P Wulff, D Kuhl, P Cohen
Biochemical Journal 2004
Mechanisms of regulation of epithelial sodium channel by SGK1 in A6 cells
DA de la Rosa, TG Paunescu, WJ Els, SI Helman, CM Canessa
The Journal of General Physiology 2004
Regulation of the epithelial sodium channel by accessory proteins
K Gormley, Y Dong, GA Sagnella
Biochemical Journal 2003
Characterizing embryonic gene expression patterns in the mouse using nonredundant sequence-based selection
R Sousa-Nunes, AA Rana, R Kettleborough, JM Brickman, M Clements, A Forrest, S Grimmond, P Avner, JC Smith, SL Dunwoodie, RS Beddington
Genome research 2003
Distribution and regulation of expression of serum- and glucocorticoid-induced kinase-1 in the rat kidney
DA de la Rosa, T Coric, N Todorovic, D Shao, T Wang, CM Canessa
The Journal of Physiology 2003
Sgk: an old enzyme revisited
N Farman, S Boulkroun, N Courtois-Coutry
Journal of Clinical Investigation 2002

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