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Citations to this article

A sobering addition to the literature on COVID-19 and the brain
Amit Mahajan, Graeme F. Mason
Amit Mahajan, Graeme F. Mason
Published March 16, 2021
Citation Information: J Clin Invest. 2021;131(8):e148376. https://doi.org/10.1172/JCI148376.
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Commentary Article has an altmetric score of 5

A sobering addition to the literature on COVID-19 and the brain

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Abstract

Several coronavirus disease 2019 (COVID-19) studies have focused on neuropathology. In this issue of the JCI, Qin, Wu, and Chen et al. focused specifically on people whose acute infection lacked obvious neurological involvement. Severely infected patients showed abnormal gray matter volumes, white matter diffusion, and cerebral blood flow compared with healthy controls and those with mild infection. The data remain associative rather than mechanistic, but correlations with systemic immune markers suggest effects of inflammation, hypercoagulation, or other aspects of disease severity. Mechanistic research is warranted. Given the lack of obvious neurological symptoms, neurocognitive assessments were not performed, but the findings suggest that such assessments may be warranted in severely affected patients, even without obvious symptoms. Further, studying CNS involvement of other disorders with overlapping pathophysiologies such as inflammation, coagulation, hypoxia, or direct viral infection may reveal the causes for COVID-19–related neuropathology.

Authors

Amit Mahajan, Graeme F. Mason

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Total citations by year

Year: 2022 2021 Total
Citations: 2 2 4
Citation information
This citation data is accumulated from CrossRef, which receives citation information from participating publishers, including this journal. Not all publishers participate in CrossRef, so this information is not comprehensive. Additionally, data may not reflect the most current citations to this article, and the data may differ from citation information available from other sources (for example, Google Scholar, Web of Science, and Scopus).

Citations to this article (4)

Title and authors Publication Year
Ethical considerations regarding animal experimentation
KIANI AK, PHEBY D, HENEHAN G, BROWN R, SIEVING P, SYKORA P, MARKS R, FALSINI B, CAPODICASA N, MIERTUS S, LORUSSO L, DONDOSSOLA D, TARTAGLIA GM, ERGOREN MC, DUNDAR M, MICHELINI S, MALACARNE D, BONETTI G, DAUTAJ A, DONATO K, MEDORI MC, BECCARI T, SAMAJA M, CONNELLY ST, MARTIN D, MORRESI A, BACU A, HERBST KL, KAPUSTIN M, STUPPIA L, LUMER L, FARRONATO G, BERTELLI M
Journal of Preventive Medicine and Hygiene 2022
Post-COVID-19 human memory impairment: A PRISMA-based systematic review of evidence from brain imaging studies
Shan D, Li S, Xu R, Nie G, Xie Y, Han J, Gao X, Zheng Y, Xu Z, Dai Z
Frontiers in aging neuroscience 2022
Role of miR-2392 in driving SARS-CoV-2 infection.
McDonald JT, Enguita FJ, Taylor D, Griffin RJ, Priebe W, Emmett MR, Sajadi MM, Harris AD, Clement J, Dybas JM, Aykin-Burns N, Guarnieri JW, Singh LN, Grabham P, Baylin SB, Yousey A, Pearson AN, Corry PM, Saravia-Butler A, Aunins TR, Sharma S, Nagpal P, Meydan C, Foox J, Mozsary C, Cerqueira B, Zaksas V, Singh U, Wurtele ES, Costes SV, Davanzo GG, Galeano D, Paccanaro A, Meinig SL, Hagan RS, Bowman NM, Wolfgang MC, Altinok S, Sapoval N, Treangen TJ, Moraes-Vieira PM, Vanderburg C, Wallace DC, Schisler JC, Mason CE, Chatterjee A, Meller R, Beheshti A
Cell Reports 2021
Persistent white matter changes in recovered COVID-19 patients at the 1-year follow-up
Huang S, Zhou Z, Yang D, Zhao W, Zeng M, Xie X, Du Y, Jiang Y, Zhou X, Yang W, Guo H, Sun H, Liu P, Liu J, Luo H, Liu J
Brain : a journal of neurology 2021

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