The antifungal antibiotic, clotrimazole, inhibits chloride secretion by human intestinal T84 cells via blockade of distinct basolateral K+ conductances. Demonstration of efficacy in intact rabbit colon and in an in vivo mouse model of cholera.

• Text
• PDF

Abstract

Research Article

Authors

P A Rufo, D Merlin, M Riegler, M H Ferguson-Maltzman, B L Dickinson, C Brugnara, S L Alper, W I Lencer