Research Article
P Ray, W Tang, P Wang, R Homer, C Kuhn 3rd, R A Flavell, J A Elias
Title and authors | Publication | Year |
---|---|---|
Emerging roles for IL-11 in inflammatory diseases
KY Fung, C Louis, RD Metcalfe, CC Kosasih, IP Wicks, MD Griffin, TL Putoczki |
Cytokine | 2022 |
Tissue and cell-type-specific transduction using rAAV vectors in lung diseases
K Kochergin-Nikitsky, L Belova, A Lavrov, S Smirnikhina |
Journal of Molecular Medicine | 2021 |
Therapeutic Targeting of IL-11 for Chronic Lung Disease
RK Kortekaas, JK Burgess, R van Orsoy, D Lamb, M Webster, R Gosens |
Trends in Pharmacological Sciences | 2021 |
Bcl2-induced DNA replication stress promotes lung carcinogenesis in response to space radiation
M Xie, D Park, GL Sica, X Deng |
Carcinogenesis | 2020 |
Interleukin-11 signaling underlies fibrosis, parenchymal dysfunction, and chronic inflammation of the airway
B Ng, SA Cook, S Schafer |
Experimental & molecular medicine | 2020 |
Modeling of Fibrotic Lung Disease Using 3D Organoids Derived from Human Pluripotent Stem Cells
A Strikoudis, A Cieślak, L Loffredo, YW Chen, N Patel, A Saqi, DJ Lederer, HW Snoeck |
Cell Reports | 2019 |
Stem Cell-Based Therapy for Lung Disease
JK Burgess, IH Heijink |
2019 | |
Context-specific regulation of cell survival by a miRNA-controlled BIM rheostat
V Labi, S Peng, F Klironomos, M Munschauer, N Kastelic, T Chakraborty, K Schoeler, E Derudder, M Martella, G Mastrobuoni, LR Hernandez-Miranda, I Lahmann, C Kocks, C Birchmeier, S Kempa, LQ de Fend, M Landthaler, N Rajewsky, K Rajewsky |
Genes & development | 2019 |
β 2 -Adrenoceptor signaling in airway epithelial cells promotes eosinophilic inflammation, mucous metaplasia, and airway contractility
LP Nguyen, NA Al-Sawalha, S Parra, I Pokkunuri, O Omoluabi, AA Okulate, EW Li, M Hazen, JM Gonzalez-Granado, CJ Daly, JC McGrath, MJ Tuvim, BJ Knoll, BF Dickey, RA Bond |
Proceedings of the National Academy of Sciences | 2017 |
Lung disease phenotypes caused by over-expression of combinations of alpha, beta, and gamma subunits of the epithelial sodium channel in mouse airways
A Livraghi-Butrico, KJ Wilkinson, AS Volmer, RC Gilmore, TD Rogers, RA Caldwell, KA Burns, CR Esther, MA Mall, RC Boucher, WK O'Neal, BR Grubb |
American journal of physiology. Lung cellular and molecular physiology | 2017 |
Compartment-Specific and Sequential Role of MyD88 and CARD9 in Chemokine Induction and Innate Defense during Respiratory Fungal Infection
A Jhingran, S Kasahara, KM Shepardson, BA Junecko, LJ Heung, DK Kumasaka, SE Knoblaugh, X Lin, BI Kazmierczak, TA Reinhart, RA Cramer, TM Hohl, BS Klein |
PLoS pathogens | 2015 |
Plasticity of Airway Epithelial Cell Transcriptome in Response to Flagellin
JG Clark, KH Kim, RS Basom, SA Gharib, YP Di |
PloS one | 2015 |
Animal Models, Learning Lessons to Prevent and Treat Neonatal Chronic Lung Disease
AH Jobe |
Frontiers in Medicine | 2015 |
Attenuation of Monocrotaline-Induced Pulmonary Hypertension by Luminal Adeno-Associated Virus Serotype 9 Gene Transfer of Prostacyclin Synthase
IB Gubrij, SR Martin, AK Pangle, R Kurten, LG Johnson |
Human Gene Therapy | 2014 |
Combined exposure to cigarette smoke and nontypeable Haemophilus influenzae drives development of a COPD phenotype in mice
S Ganesan, AT Comstock, B Kinker, P Mancuso, JM Beck, US Sajjan |
Respiratory Research | 2014 |
IL-13 receptor α2 contributes to development of experimental allergic asthma
W Chen, U Sivaprasad, AM Gibson, MB Ericksen, CM Cunningham, SA Bass, KG Kinker, FD Finkelman, M Wills-Karp, GK Hershey |
Journal of Allergy and Clinical Immunology | 2013 |
IL-18 Induces Emphysema and Airway and Vascular Remodeling via IFN-γ, IL-17A, and IL-13
MJ Kang, JM Choi, BH Kim, CM Lee, WK Cho, G Choe, DH Kim, CG Lee, JA Elias |
American journal of respiratory and critical care medicine | 2012 |
α1-Antitrypsin Deficiency
D Perlmutter |
Zakim and Boyer s Hepatology | 2012 |
The Newborn Lung: Neonatology Questions and Controversies
GG Konduri |
The Newborn Lung: Neonatology Questions and Controversies | 2012 |
Long-term reparative effects of mesenchymal stem cell therapy following neonatal hyperoxia-induced lung injury
RP Sutsko, KC Young, A Ribeiro, E Torres, M Rodriguez, D Hehre, C Devia, I McNiece, C Suguihara |
Pediatric Research | 2012 |
Airway epithelial MyD88 restores control of Pseudomonas aeruginosa murine infection via an interleukin-1 dependent pathway
LA Mijares, T Wangdi, C Sokol, R Homer, R Medzhitov, BI Kazmierczak |
Journal of immunology (Baltimore, Md. : 1950) | 2011 |
Genetically manipulated mouse models of lung disease: potential and pitfalls
RM Baron, AJ Choi, CA Owen, AM Choi |
American journal of physiology. Lung cellular and molecular physiology | 2011 |
The construction of transgenic and gene knockout/knockin mouse models of human disease
A Doyle, MP McGarry, NA Lee, JJ Lee |
Transgenic Research | 2011 |
Conditional Expression of Oncogenic C-RAF in Mouse Pulmonary Epithelial Cells Reveals Differential Tumorigenesis and Induction of Autophagy Leading to Tumor Regression12
F Ceteci, J Xu, S Ceteci, E Zanucco, C Thakur, UR Rapp |
Neoplasia (New York, N.Y.) | 2011 |
Use of a New-Generation Reverse Tetracycline Transactivator System for Quantitative Control of Conditional Gene Expression in the Murine Lung
J Duerr, M Gruner, SC Schubert, U Haberkorn, H Bujard, MA Mall |
American journal of respiratory cell and molecular biology | 2011 |
Lymphotoxin-alpha contributes to lymphangiogenesis
RH Mounzer, OS Svendsen, P Baluk, CM Bergman, TP Padera, H Wiig, RK Jain, DM McDonald, NH Ruddle |
Blood | 2010 |
Inactivation of I kappaB-kinase-beta dependent genes in airway epithelium reduces tobacco smoke induced acute airway inflammation
SY Lee, M Miller, JY Cho, DJ Song, M Karin, DH Broide |
International Immunopharmacology | 2010 |
Epithelial reticulon 4B (Nogo-B) is an endogenous regulator of Th2-driven lung inflammation
PL Wright, J Yu, YP Di, RJ Homer, G Chupp, JA Elias, L Cohn, WC Sessa |
Journal of Experimental Medicine | 2010 |
Nuclear Hormone Retinoid X Receptor (RXR) Negatively Regulates the Glucose-Stimulated Insulin Secretion of Pancreatic -Cells
S Miyazaki, H Taniguchi, Y Moritoh, F Tashiro, T Yamamoto, E Yamato, H Ikegami, K Ozato, J Miyazaki |
Diabetes | 2010 |
Elastase- and LPS-exposed mice display altered responses to rhinovirus infection
U Sajjan, S Ganesan, AT Comstock, J Shim, Q Wang, DR Nagarkar, Y Zhao, AM Goldsmith, J Sonstein, MJ Linn, JL Curtis, MB Hershenson |
American journal of physiology. Lung cellular and molecular physiology | 2009 |
Determinants of initiation and progression of idiopathic pulmonary fibrosis
RM KOTTMANN, CM HOGAN, RP PHIPPS, PJ SIME |
Respirology | 2009 |
IL-12 p80-dependent macrophage recruitment primes the host for increased survival following a lethal respiratory viral infection
S Gunsten, CL Mikols, MH Grayson, RA Schwendener, E Agapov, RM Tidwell, CL Cannon, SL Brody, MJ Walter |
Immunology | 2009 |
Sox2 Is Required for Maintenance and Differentiation of Bronchiolar Clara, Ciliated, and Goblet Cells
DH Tompkins, V Besnard, AW Lange, SE Wert, AR Keiser, AN Smith, R Lang, JA Whitsett |
PloS one | 2009 |
Middleton's Allergy: Principles and Practice
RP Schleimer |
Middleton's Allergy: Principles and Practice | 2009 |
Matrix Metalloproteinase-9 Deficiency Worsens Lung Injury in a Model of Bronchopulmonary Dysplasia
H Lukkarinen, A Hogmalm, U Lappalainen, K Bry |
American journal of respiratory cell and molecular biology | 2009 |
Molecular cloning and functional analysis of the FSH receptor gene promoter from the volcano mouse (Neotomodon alstoni alstoni)
MA Pérez-Solis, H Macías, A Acosta-MontesdeOca, AM Pasapera, R Fierro, A Ulloa-Aguirre, R Gutiérrez-Sagal |
Endocrine | 2009 |
Fas-ligand-induced apoptosis of respiratory epithelial cells causes disruption of postcanalicular alveolar development
ME de Paepe, S Gundavarapu, U Tantravahi, JR Pepperell, SA Haley, FI Luks, Q Mao |
The American Journal of Pathology | 2008 |
Endogenous IL-11 signaling is essential in Th2- and IL-13-induced inflammation and mucus production
CG Lee, D Hartl, H Matsuura, FM Dunlop, PD Scotney, LJ Fabri, AD Nash, NY Chen, CY Tang, Q Chen, RJ Homer, M Baca, JA Elias |
American journal of respiratory cell and molecular biology | 2008 |
Developmental regulation of NO-mediated VEGF-induced effects in the lung
V Bhandari, R Choo-Wing, CG Lee, K Yusuf, JH Nedrelow, N Ambalavanan, H Malkus, RJ Homer, JA Elias |
American journal of respiratory cell and molecular biology | 2008 |
Divergent roles of endothelial NF-kappaB in multiple organ injury and bacterial clearance in mouse models of sepsis
X Ye, J Ding, X Zhou, G Chen, SF Liu |
Journal of Experimental Medicine | 2008 |
Selective p38α mitogen-activated protein kinase inhibitor attenuates lung inflammation and fibrosis in IL-13 transgenic mouse model of asthma
JY Ma, S Medicherla, I Kerr, R Mangadu, AA Protter, LS Higgins |
Journal of asthma and allergy | 2008 |
Wnt signaling in lung organogenesis
SP de Langhe, SD Reynolds |
Organogenesis | 2008 |
Intrathecal coelectrotransfer of a tetracycline-inducible, three-plasmid-based system to achieve tightly regulated antinociceptive gene therapy for mononeuropathic rats
KH Chen, CH Wu, CC Tseng, JM Shiau, CT Lee, CR Lin |
The Journal of Gene Medicine | 2008 |
Rat aquaporin-5 4.3-kb 5′-flanking region differentially regulates expression in salivary gland and lung in vivo
B Zhou, DK Ann, P Flodby, P Minoo, JM Liebler, ED Crandall, Z Borok |
American journal of physiology. Cell physiology | 2008 |
Cre-mediated recombination in mouse Clara cells
HG Li, SN Cho, CM Evans, BF Dickey, JW Jeong, FJ DeMayo |
genesis | 2008 |
VEGF-induced heme oxygenase-1 confers cytoprotection from lethal hyperoxia in vivo
JM Siner, G Jiang, ZI Cohen, P Shan, X Zhang, CG Lee, JA Elias, PJ Lee |
The FASEB Journal | 2007 |
Building better mouse models of asthma.
Lloyd CM |
Current Allergy and Asthma Reports | 2007 |
Airway Inflammation and Bronchial Remodelling in Toluene Diisocyanate-exposed BALB/c Mouse Model
LZ Sun, S Elsayed, AM Bronstad, TV Do, Å Irgens, NP Aardal, TB Aasen |
Scandinavian Journal of Immunology | 2007 |
Adenosine Metabolism and Murine Strain-Specific IL-4-Induced Inflammation, Emphysema and Fibrosis
Bing Ma, Michael R. Blackburn, Chun Geun Lee, Robert J. Homer, Wei Liu, Richard A. Flavell, Lynn Boyden, Richard P. Lifton, Chun-Xiao Sun, Hays W. Young, Jack A. Elias |
Journal of Clinical Investigation | 2006 |
Expression of the reverse tetracycline-transactivator gene causes emphysema-like changes in mice
TH Sisson, JM Hansen, M Shah, KE Hanson, M Du, T Ling, RH Simon, PJ Christensen |
American journal of respiratory cell and molecular biology | 2006 |
Adeno-associated virus serotype 9 vectors transduce murine alveolar and nasal epithelia and can be readministered
MP Limberis, JM Wilson |
Proceedings of the National Academy of Sciences | 2006 |
Impaired mesenchymal cell function in Gata4 mutant mice leads to diaphragmatic hernias and primary lung defects
PY Jay, M Bielinska, JM Erlich, S Mannisto, WT Pu, M Heikinheimo, DB Wilson |
Developmental Biology | 2006 |
Conditional expression of interferon-γ to enhance host responses to pulmonary bacterial infection
S Ruan, E Young, MJ Luce, J Reiser, JK Kolls, JE Shellito |
Pulmonary Pharmacology & Therapeutics | 2006 |
Stage-specific Effects of cAMP Signaling during Distal Lung Epithelial Development
J Xu, J Tian, SM Grumelli, KJ Haley, SD Shapiro |
The Journal of biological chemistry | 2006 |
Bcl-2-Related Protein A1 Is An Endogenous and Cytokine-Stimulated Mediator of Cytoprotection in Hyperoxia Acute Lung Injury
Chuan Hua He, Aaron B. Waxman, Chun Geun Lee, Holger Link, Morgan E. Rabach, Bing Ma, Qingsheng Chen, Zhou Zhu, Keiko Nakayama, Keiichi I. Nakayama, Robert Homer, Jack A. Elias |
Journal of Clinical Investigation | 2005 |
BLT1-mediated T cell trafficking is critical for rejection and obliterative bronchiolitis after lung transplantation
BD Medoff, E Seung, JC Wain, TK Means, GS Campanella, SA Islam, SY Thomas, LC Ginns, N Grabie, AH Lichtman, AM Tager, AD Luster |
Journal of Experimental Medicine | 2005 |
Allergen-induced peribronchial fibrosis and mucus production mediated by IkappaB kinase beta-dependent genes in airway epithelium
DH Broide, T Lawrence, T Doherty, JY Cho, M Miller, K McElwain, S McElwain, M Karin |
Proceedings of the National Academy of Sciences | 2005 |
Pathological role of IL-6 in the experimental allergic bronchial asthma in mice.
Doganci A, Sauer K, Karwot R, Finotto S |
Clinical Reviews in Allergy & Immunology | 2005 |
Conditional expression of the mutant Ki-rasG12C allele results in formation of benign lung adenomas: development of a novel mouse lung tumor model
HS Floyd, CL Farnsworth, ND Kock, MC Mizesko, JL Little, ST Dance, J Everitt, J Tichelaar, JA Whitsett, MS Miller |
Carcinogenesis | 2005 |
Techniques in the Behavioral and Neural Sciences
S Coste, S Murray, M Stenzelpoore |
Techniques in the Behavioral and Neural Sciences | 2005 |
Nuclear Factor of Activated T Cells and Serum Response Factor Cooperatively Regulate the Activity of an α-Actin Intronic Enhancer
LV Bosc, JJ Layne, MT Nelson, DC Hill-Eubanks |
The Journal of biological chemistry | 2005 |
Chronic endotoxin exposure does not cause sustained structural abnormalities in the fetal sheep lungs
SG Kallapur, I Nitsos, TJ Moss, BW Kramer, JP Newnham, M Ikegami, AH Jobe |
American journal of physiology. Lung cellular and molecular physiology | 2005 |
Animal Models of T Cell-Mediated Skin Diseases
T Zollner, H Renz, K Asadullah |
2005 | |
IL-11 Receptor α in the Pathogenesis of IL-13-Induced Inflammation and Remodeling
Q Chen, L Rabach, P Noble, T Zheng, CG Lee, RJ Homer, JA Elias |
Journal of immunology (Baltimore, Md. : 1950) | 2005 |
Expression of nitric oxide synthase-2 in the lungs decreases airway resistance and responsiveness
J Hjoberg, S Shore, L Kobzik, S Okinaga, A Hallock, J Vallone, V Subramaniam, GT de Sanctis, JA Elias, JM Drazen, ES Silverman |
Journal of applied physiology | 2004 |
Airway Remodeling: Lessons From Animal Models
D Ramos-Barbón, MS Ludwig, JG Martin |
Clinical Reviews in Allergy & Immunology | 2004 |
Vascular endothelial growth factor (VEGF) induces remodeling and enhances TH2-mediated sensitization and inflammation in the lung
CG Lee, H Link, P Baluk, RJ Homer, S Chapoval, V Bhandari, MJ Kang, L Cohn, YK Kim, DM McDonald, JA Elias |
Nature Medicine | 2004 |
Mouse Models of Human Cancer
R Benezra, S Rafii, D Lyden |
Mouse Models of Human Cancer | 2004 |
Regulated angiogenesis and vascular regression in mice overexpressing vascular endothelial growth factor in airways
P Baluk, CG Lee, H Link, E Ator, A Haskell, JA Elias, DM McDonald |
The American Journal of Pathology | 2004 |
Partial reconstitution of V(D)J rearrangement and lymphocyte development in RAG-deficient mice expressing inducible, tetracycline-regulated RAG transgenes
PE Shockett, S Zhou, X Hong, DG Schatz |
Molecular Immunology | 2004 |
Genetically Engineered Mouse Models for Lung Cancer
I Kwak, SY Tsai, FJ DeMayo |
Annual Review of Physiology | 2004 |
Models of chronic obstructive pulmonary disease: a review of current status
JC Fox, MF Fitzgerald |
Drug Discovery Today: Disease Models | 2004 |
Molekularmedizinische Grundlagen von altersspezifischen Erkrankungen
D Ganten, K Ruckpaul, A Ruiz-Torres |
2004 | |
Hematopoietic Growth Factors in Oncology
G Morstyn, MA Foote, GJ Lieschke |
2004 | |
Bronchopulmonary Dysplasia in Preterm Infants: Pathophysiology and Management Strategies
CT DAngio, WM Maniscalco |
Pediatric Drugs | 2004 |
A prominent role for airway epithelial NF-kappa B activation in lipopolysaccharide-induced airway inflammation
ME Poynter, CG Irvin, YM Janssen-Heininger |
Journal of immunology (Baltimore, Md. : 1950) | 2003 |
Inducible expression of keratinocyte growth factor (KGF) in mice inhibits lung epithelial cell death induced by hyperoxia
P Ray, Y Devaux, DB Stolz, M Yarlagadda, SC Watkins, Y Lu, L Chen, XF Yang, A Ray |
Proceedings of the National Academy of Sciences | 2003 |
The role of gp130/IL-6 cytokines in the development of pulmonary fibrosis: critical determinants of disease susceptibility and progression?
DA Knight, M Ernst, GP Anderson, YP Moodley, SE Mutsaers |
Pharmacology & Therapeutics | 2003 |
Requirement of transcription factor NFAT in developing atrial myocardium
W Schubert, XY Yang, TT Yang, SM Factor, MP Lisanti, JD Molkentin, M Rincon, CW Chow |
The Journal of Cell Biology | 2003 |
IL-11 and IL-17 expression in nasal polyps: Relationship to collagen deposition and suppression by intranasal fluticasone propionate
SM Molet, QA Hamid, DL Hamilos |
The Laryngoscope | 2003 |
Inducible, brain region-specific expression of a dominant negative mutant of c-Jun in transgenic mice decreases sensitivity to cocaine
MC Peakman, C Colby, LI Perrotti, P Tekumalla, T Carle, P Ulery, J Chao, C Duman, C Steffen, L Monteggia, MR Allen, JL Stock, RS Duman, JD McNeish, M Barrot, DW Self, EJ Nestler, E Schaeffer |
Brain Research | 2003 |
Lung Biology in Health and Disease
N Zamel |
Lung Biology in Health and Disease: Experimental Models and Therapeutic Potential | 2003 |
Transgenic modeling of interleukin-13 in the lung
JA Elias, T Zheng, CG Lee, RJ Homer, Q Chen, B Ma, M Blackburn, Z Zhu |
Chest | 2003 |
Plunging into the Chaos of the Cytokine/Chemokine Cocktail in Pulmonary Fibrosis: How Many and How Important Are They?
M Selman |
American journal of respiratory and critical care medicine | 2003 |
Epithelial Cell Modulation of Airway Fibrosis in Asthma
MA Olman |
American journal of respiratory cell and molecular biology | 2003 |
Transforming growth factor-β induces fibrosis in immune cell-depleted lungs
MA Olman, MA Matthay |
American journal of physiology. Lung cellular and molecular physiology | 2003 |
Overexpression of IL-9 in the Lung Leads to Th2 Cytokine Expression which is Essential for Immune Pathology
Ulla-Angela Temann, Prabir Ray, Richard A. Flavell |
Journal of Clinical Investigation | 2002 |
Overlapping and enzyme-specific contributions of matrix metalloproteinase (MMP)-9 and MMP-12 to the pathogenesis of IL-13-induced inflammation and alveolar remodeling in the lung
Sophie Lanone, Tao Zheng, Zhou Zhu, Wei Liu, Chun Geun Lee, Bing Ma, Qingsheng Chen, Robert J. Homer, Jingming Wang, Lesley A. Rabach, Morgan E. Rabach, J. Michael Shipley, Steven D. Shapiro, Robert M. Senior, Jack A. Elias |
Journal of Clinical Investigation | 2002 |
Chronic obstructive pulmonary disease * 3: Experimental animal models of pulmonary emphysema
R Mahadeva, SD Shapiro |
Thorax | 2002 |
Tetracycline-controlled transcriptional regulation systems: advances and application in transgenic animal modeling
Z Zhu, T Zheng, CG Lee, RJ Homer, JA Elias |
Seminars in Cell & Developmental Biology | 2002 |
STUDYINGGENEFUNCTION INEUKARYOTES BYCONDITIONALGENEINACTIVATION
M Gossen, H Bujard |
Annual Review of Genetics | 2002 |
Gene Therapy in Lung Disease
K Amin |
Gene Therapy in Lung Disease | 2002 |
Pseudomonas aeruginosa and Tumor Necrosis Factor- α Attenuate Clara Cell Secretory Protein Promoter Function
KS Harrod, RJ Jaramillo |
American journal of respiratory cell and molecular biology | 2002 |
Conditional gene expression in the respiratory epithelium of the mouse
AK Perl, JW Tichelaar, JA Whitsett |
Transgenic Research | 2002 |
Animal Models of Cigarette Smoke-Induced COPD*
JL Wright, A Churg |
Chest | 2002 |
Inducible lung-specific urokinase expression reduces fibrosis and mortality after lung injury in mice
TH Sisson, KE Hanson, N Subbotina, A Patwardhan, N Hattori, RH Simon |
American journal of physiology. Lung cellular and molecular physiology | 2002 |
Mesenchymal-epithelial interactions in lung development and repair: are modeling and remodeling the same process?
F Demayo, P Minoo, CG Plopper, L Schuger, J Shannon, JS Torday |
American journal of physiology. Lung cellular and molecular physiology | 2002 |
Animal models of chronic obstructive pulmonary disease
PA Dawkins, RA Stockley |
Thorax | 2001 |
Activated Akt protects the lung from oxidant-induced injury and delays death of mice
Y Lu, L Parkyn, LE Otterbein, Y Kureishi, K Walsh, A Ray, P Ray |
Journal of Experimental Medicine | 2001 |
Activated Akt Protects the Lung from Oxidant-Induced Injury and Delays Death of Mice
Y Lu, L Parkyn, LE Otterbein, Y Kureishi, K Walsh, A Ray, P Ray |
Journal of Experimental Medicine | 2001 |
Targeted gene regulation and gene ablation
FJ DeMayo, SY Tsai |
Trends in Endocrinology & Metabolism | 2001 |
Interleukin-11 Up-Regulates Survivin Expression in Endothelial Cells through a Signal Transducer and Activator of Transcription-3 Pathway
K Mahboubi, F Li, J Plescia, NC Kirkiles-Smith, M Mesri, Y Du, JM Carroll, JA Elias, DC Altieri, JS Pober |
Laboratory Investigation | 2001 |
IL-11: Insights in asthma from overexpression transgenic modeling
T Zheng, Z Zhu, J Wang, RJ Homer, JA Elias |
Journal of Allergy and Clinical Immunology | 2001 |
Airway inflammation and remodeling in asthma. Lessons from interleukin 11 and interleukin 13 transgenic mice
Z Zhu, CG Lee, T Zheng, G Chupp, J Wang, RJ Homer, PW Noble, Q Hamid, JA Elias |
American journal of respiratory and critical care medicine | 2001 |
Lung Biology in Health and Disease: Pathogenesis and Clinical Management
R Ballard |
Lung Biology in Health and Disease: Experimental Models and Therapeutic Potential | 2001 |
Transgenic Models for Study of Lung Morphogenesis and Repair
JA Whitsett, SW Glasser, JW Tichelaar, AK Perl, JC Clark, SE Wert |
Chest | 2001 |
Adenosine deaminase-deficient mice as models for adenosine-mediated lung inflammation and damage
MR Blackburn, H Zhong |
Drug Development Research | 2001 |
CCSP modulates airway dysfunction and host responses in an Ova-challenged mouse model
SZ Wang, CL Rosenberger, TM Espindola, EG Barrett, Y Tesfaigzi, DE Bice, KS Harrod |
American journal of physiology. Lung cellular and molecular physiology | 2001 |
Inducible, pharmacogenetic approaches to the study of learning and memory
M Ohno, PW Frankland, AP Chen, RM Costa, AJ Silva |
Nature Neuroscience | 2001 |
Tetracyclines in Biology, Chemistry and Medicine
M Nelson, W Hillen, RA Greenwald |
2001 | |
Inducible targeting of IL-13 to the adult lung causes matrix metalloproteinase- and cathepsin-dependent emphysema
Tao Zheng, Zhou Zhu, Zhongde Wang, Robert J. Homer, Bing Ma, Richard J. Riese, Jr., Harold A. Chapman, Jr., Steven D. Shapiro, Jack A. Elias |
Journal of Clinical Investigation | 2000 |
IL-13 stimulates vascular endothelial cell growth factor and protects against hyperoxic acute lung injury
J Corne, G Chupp, CG Lee, RJ Homer, Z Zhu, Q Chen, B Ma, Y Du, F Roux, J McArdle, AB Waxman, JA Elias |
Journal of Clinical Investigation | 2000 |
Metabolic Consequences of Adenosine Deaminase Deficiency in Mice Are Associated with Defects in Alveogenesis, Pulmonary Inflammation, and Airway Obstruction
MR Blackburn, JB Volmer, JL Thrasher, H Zhong, JR Crosby, JJ Lee, RE Kellems |
Journal of Experimental Medicine | 2000 |
Metabolic consequences of adenosine deaminase deficiency in mice are associated with defects in alveogenesis, pulmonary inflammation, and airway obstruction
MR Blackburn, JB Volmer, JL Thrasher, H Zhong, JR Crosby, JJ Lee, RE Kellems |
Journal of Experimental Medicine | 2000 |
Interferon gamma induction of pulmonary emphysema in the adult murine lung
Z Wang, T Zheng, Z Zhu, RJ Homer, RJ Riese, HA Chapman, SD Shapiro, JA Elias |
Journal of Experimental Medicine | 2000 |
MECHANISMS OF REPAIR AND REMODELING FOLLOWING ACUTE LUNG INJURY
DH Ingbar |
Clinics in Chest Medicine | 2000 |
gp130-mediated signalling as a therapeutic target
T Ohtani, K Ishihara, T Atsumi, Y Yoshida, K Nishida, M Narimatsu, T Shirogane, M Hibi, T Hirano |
Expert Opinion on Therapeutic Targets | 2000 |
CONSEQUENCES OF LONG-TERM INFLAMMATION
RJ Homer, JA Elias |
Clinics in Chest Medicine | 2000 |
IL-11 expression is increased in severe asthma: Association with epithelial cells and eosinophils
E Minshall, J Chakir, M Laviolette, S Molet, Z Zhu, R Olivenstein, JA Elias, Q Hamid |
Journal of Allergy and Clinical Immunology | 2000 |
Airway hyperresponsiveness and airway obstruction in transgenic mice. Morphologic correlates in mice overexpressing interleukin (IL)-11 and IL-6 in the lung
CK 3rd, RJ Homer, Z Zhu, N Ward, RA Flavell, GP Geba, JA Elias |
American journal of respiratory cell and molecular biology | 2000 |
Animal Models for Chronic Obstructive Pulmonary Disease: Age of Klotho and Marlboro Mice
SD Shapiro |
American journal of respiratory cell and molecular biology | 2000 |
Morphometry explains variation in airway responsiveness in transgenic mice overexpressing interleukin-6 and interleukin-11 in the lung
C Kuhn, RJ Homer, Z Zhu, N Ward, JA Elias |
Chest | 2000 |
Inducible lung-specific expression of RANTES: preferential recruitment of neutrophils
ZZ Pan, L Parkyn, A Ray, P Ray |
American journal of physiology. Lung cellular and molecular physiology | 2000 |
Conditional Expression of Fibroblast Growth Factor-7 in the Developing and Mature Lung
JW Tichelaar, W Lu, JA Whitsett |
The Journal of biological chemistry | 2000 |
Cellular Mechanisms in Airways Inflammation
CP Page, KH Banner, D Spina |
2000 | |
Antenatal Endotoxin and Glucocorticoid Effects on Lung Morphometry in Preterm Lambs:
KE Willet, AH Jobe, M Ikegami, J Newnham, , PD Sly |
Pediatric Research | 2000 |
IL-11 Selectively Inhibits Aeroallergen-Induced Pulmonary Eosinophilia and Th2 Cytokine Production
J Wang, RJ Homer, L Hong, L Cohn, CG Lee, S Jung, JA Elias |
Journal of immunology (Baltimore, Md. : 1950) | 2000 |
Inducible Gene Expression and Gene Modification in Transgenic Mice
F Jaisser |
Journal of the American Society of Nephrology : JASN | 2000 |
Pulmonary expression of interleukin-13 causes inflammation, mucus hypersecretion, subepithelial fibrosis, physiologic abnormalities, and eotaxin production
Z Zhu, RJ Homer, Z Wang, Q Chen, GP Geba, J Wang, Y Zhang, JA Elias |
Journal of Clinical Investigation | 1999 |
Emphysematous Lesions, Inflammation, and Fibrosis in the Lungs of Transgenic Mice Overexpressing Platelet-Derived Growth Factor
GW Hoyle, J Li, JB Finkelstein, T Eisenberg, JY Liu, JA Lasky, G Athas, GF Morris, AR Brody |
The American Journal of Pathology | 1999 |
Reduced Tumor Necrosis Factor-α and Transforming Growth Factor-β1 Expression in the Lungs of Inbred Mice that Fail to Develop Fibroproliferative Lesions Consequent to Asbestos Exposure
DM Brass, GW Hoyle, HG Poovey, JY Liu, AR Brody |
The American Journal of Pathology | 1999 |
Reduced tumor necrosis factor-alpha and transforming growth factor-beta1 expression in the lungs of inbred mice that fail to develop fibroproliferative lesions consequent to asbestos exposure
DM Brass, GW Hoyle, HG Poovey, JY Liu, AR Brody |
The American Journal of Pathology | 1999 |
Inhibition of Allergic Inflammation in a Murine Model of Asthma by Expression of a Dominant-Negative Mutant of GATA-3
DH Zhang, L Yang, L Cohn, L Parkyn, R Homer, P Ray, A Ray |
Immunity | 1999 |
Modulation of cell growth and transformation by doxycycline-regulated FGF-2 expression in NIH-3T3 cells
A Gualandris, M Arese, B Shen, DB Rifkin |
Journal of Cellular Physiology | 1999 |
The New BPD: An Arrest of Lung Development
AJ Jobe |
Pediatric Research | 1999 |
The T3b gene promoter directs intestinal epithelial cell-specific expression in transgenic mice
H Aihara, N Hiwatashi, S Kumagai, Y Obata, T Shimosegawa, T Toyota, J Miyazaki |
FEBS Letters | 1999 |
Nonviral Vectors for Gene Therapy
U Griesenbach, DM Geddes, EW Alton |
Nonviral Vectors for Gene Therapy | 1999 |
Myofibroblasts. I. Paracrine cells important in health and disease
D Li, SL Friedman |
The American journal of physiology | 1999 |
Use of Animal Models in the Study of Inflammatory Mediators of Pneumonia
B Mehrad, TJ Standiford |
ILAR journal / National Research Council, Institute of Laboratory Animal Resources | 1999 |
Airway Remodeling and Repair
W Busse, J Elias, D Sheppard, S Banks-Schlegel |
American journal of respiratory and critical care medicine | 1999 |
Dexamethasone regulation of lung epithelial cell and fibroblast interleukin-11 production
J Wang, Z Zhu, R Nolfo, JA Elias |
American journal of physiology. Lung cellular and molecular physiology | 1999 |
Submucosal gland development in the airway is controlled by lymphoid enhancer binding factor 1 (LEF1)
D Duan, Y Yue, W Zhou, B Labed, TC Ritchie, R Grosschedl, JF Engelhardt |
Development (Cambridge, England) | 1999 |
Advanced transgenic and gene-targeting approaches
X Gao, A Kemper, B Popko |
Neurochemical Research | 1999 |
Targeted lung expression of interleukin-11 enhances murine tolerance of 100% oxygen and diminishes hyperoxia-induced DNA fragmentation
AB Waxman, O Einarsson, T Seres, RG Knickelbein, JB Warshaw, R Johnston, RJ Homer, JA Elias |
Journal of Clinical Investigation | 1998 |
Targeted lung expression of interleukin-11 enhances murine tolerance of 100% oxygen and diminishes hyperoxia-induced DNA fragmentation
AB Waxman, O Einarsson, T Seres, RG Knickelbein, JB Warshaw, R Johnston, RJ Homer, JA Elias |
Journal of Clinical Investigation | 1998 |
Essential role of nuclear factor kappaB in the induction of eosinophilia in allergic airway inflammation
L Yang, L Cohn, DH Zhang, R Homer, A Ray, P Ray |
Journal of Experimental Medicine | 1998 |
Expression of interleukin 9 in the lungs of transgenic mice causes airway inflammation, mast cell hyperplasia, and bronchial hyperresponsiveness
UA Temann, GP Geba, JA Rankin, RA Flavell |
Journal of Experimental Medicine | 1998 |
Essential Role of Nuclear Factor B in the Induction of Eosinophilia in Allergic Airway Inflammation
L Yang, L Cohn, DH Zhang, R Homer, A Ray, P Ray |
Journal of Experimental Medicine | 1998 |
Interleukin-13 induces human monocyte/macrophage fusion and macrophage mannose receptor expression
JA Rankin, DE Picarella, GP Geba, UA Temann, B Prasad, B DiCosmo, A Tarallo, B Stripp, J Whitsett, RA Flavell |
Journal of immunology (Baltimore, Md. : 1950) | 1997 |
The lung enriched transcription factor TTF-1 and the ubiquitously expressed proteins Sp1 and Sp3 interact with elements located in the minimal promoter of the rat Clara cell secretory protein gene
RF Toonen, S Gowan, CD Bingle |
Biochemical Journal | 1996 |
Transcriptional regulation of a mouse Clara cell-specific protein (mCC10) gene by the NKx transcription factor family members thyroid transciption factor 1 and cardiac muscle-specific homeobox protein (CSX)
MK Ray, CY Chen, RJ Schwartz, FJ DeMayo |
Molecular and cellular biology | 1996 |
Role of hepatocyte nuclear factor-3 alpha and hepatocyte nuclear factor-3 beta in Clara cell secretory protein gene expression in the bronchiolar epithelium
CD Bingle, BP Hackett, M Moxley, W Longmore, JD Gitlin |
Biochemical Journal | 1995 |
Primary structure of hepatocyte nuclear factor/forkhead homologue 4 and characterization of gene expression in the developing respiratory and reproductive epithelium
BP Hackett, SL Brody, M Liang, ID Zeitz, LA Bruns, JD Gitlin |
Proceedings of the National Academy of Sciences | 1995 |
Airway epithelial cell expression of interleukin-6 in transgenic mice. Uncoupling of airway inflammation and bronchial hyperreactivity
BF DiCosmo, GP Geba, D Picarella, JA Elias, JA Rankin, BR Stripp, JA Whitsett, RA Flavell |
Journal of Clinical Investigation | 1994 |
Utilization of modified surfactant-associated protein B for delivery of DNA to airway cells in culture
JE Baatz, MD Bruno, PJ Ciraolo, SW Glasser, BR Stripp, KL Smyth, TR Korfhagen |
Proceedings of the National Academy of Sciences | 1994 |
Structure and alternate tissue-preferred transcription initiation of the mouse alpha B-crystallin/small heat shock protein gene
PH Frederikse, RA Dubin, JI 2nd, J Piatigorsky |
Nucleic Acids Research | 1994 |
Tissue-specific expression of the gene coding for human Clara cell 10-kD protein, a phospholipase A2-inhibitory protein
A Peri, E Cordella-Miele, L Miele, AB Mukherjee |
Journal of Clinical Investigation | 1993 |
Identification of hepatocyte nuclear factor-3 binding sites in the Clara cell secretory protein gene
CD Bingle, JD Gitlin |
Biochemical Journal | 1993 |
The lung-specific CC10 gene is regulated by transcription factors from the AP-1, octamer, and hepatocyte nuclear factor 3 families
PL Sawaya, BR Stripp, JA Whitsett, DS Luse |
Molecular and cellular biology | 1993 |
The cells of the tracheobronchial epithelium of the mouse: a quantitative light and electron microscope study
W Tang, GP Geba, T Zheng, P Ray, RJ Homer, CK 3rd, RA Flavell, JA Elias |
Journal of Clinical Investigation | 1981 |
The cells of the tracheobronchial epithelium of the mouse: a quantitative light and electron microscope study
W Tang, GP Geba, T Zheng, P Ray, RJ Homer, CK 3rd, RA Flavell, JA Elias |
Journal of Clinical Investigation | 1981 |