JCI - Citations to Endogenous production of interleukin 15 by activated human monocytes is critical for optimal production of interferon-gamma by natural killer cells in vitro.

Citations to this article

Endogenous production of interleukin 15 by activated human monocytes is critical for optimal production of interferon-gamma by natural killer cells in vitro.

W E Carson, … , K Grabstein, M A Caligiuri

W E Carson, … , K Grabstein, M A Caligiuri

Published December 1, 1995
Citation Information: J Clin Invest. 1995;96(6):2578-2582. https://doi.org/10.1172/JCI118321.

View: Text | PDF

Research Article

Total citations by year

Year:	2025	2024	2023	2022	2021	2020	2019	2018	2017	2016	2015	2014	2013	2012	2011	2010	2009	2008	2007	2006	2005	2004	2003	2002	2001	2000	1999	1998	1997	1996	Total
Citations:	3	3	3	3	5	5	8	6	2	5	2	7	8	2	13	2	8	12	5	13	11	13	11	20	17	15	17	13	12	8	252

Citation information

Citations to this article (252)

Title and authors	Publication	Year
Fucoidan alginate and sulfated alginate microbeads induce distinct coagulation, inflammatory and fibrotic responses Vasuthas K, Kjesbu JS, Brambilla A, Levitan M, Coron AE, Fonseca DM, Strand BL, Slupphaug G, Rokstad AM	Materials Today Bio	2025
Targeting γc family cytokines with biologics: current status and future prospects Bick F, Blanchetot C, Lambrecht BN, Schuijs MJ	mAbs	2025
Inhibition of TIGIT on NK cells improves their cytotoxicity and HIV reservoir eradication potential Wang Y, Li Y, Chen J, Guo C, Yu X, Zhang Z, Fu Y, Han X, Hu Q, Ding H, Shang H, Jiang Y	mBio	2025
Swollen Feet: Considering the Paradoxical Roles of Interleukins in Nephrotic Syndrome Kovalik ME, Dacanay MA, Crowley SD, Hall G	Biomedicines	2024
A Critical Role of Culture Medium Selection in Maximizing the Purity and Expansion of Natural Killer Cells Kusch N, Storm J, Macioszek A, Kisselmann E, Knabbe C, Kaltschmidt B, Kaltschmidt C	Cells	2024
Comprehensive snapshots of natural killer cells functions, signaling, molecular mechanisms and clinical utilization Chen S, Zhu H, Jounaidi Y	Signal Transduction and Targeted Therapy	2024
The Function of NK Cells in Tumor Metastasis and NK Cell-Based Immunotherapy Yu Y	Cancers	2023
Exploiting an Interleukin-15 Heterodimeric Agonist (N803) for Effective Immunotherapy of Solid Malignancies Lui G, Minnar CM, Soon-Shiong P, Schlom J, Gameiro SR	Cells	2023
Interleukin-15 in kidney disease and therapeutics. Hall G	Current Opinion in Nephrology and Hypertension	2023
COVID-19 lung disease shares driver AT2 cytopathic features with Idiopathic pulmonary fibrosis. Sinha S, Castillo V, Espinoza CR, Tindle C, Fonseca AG, Dan JM, Katkar GD, Das S, Sahoo D, Ghosh P	EBioMedicine	2022
Allergic rhinitis, allergic contact dermatitis and disease comorbidity belong to separate entities with distinct composition of T-cell subsets, cytokines, immunoglobulins and autoantibodies. Chai W, Zhang X, Lin M, Chen Z, Wang X, Wang C, Chen A, Wang C, Wang H, Yue H, Gui J	Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology	2022
IFN-γ and TGF-β, Crucial Players in Immune Responses: A Tribute to Howard Young Gauthier T, Chen W	Journal of Interferon & Cytokine Research	2022
Functional NK Cell Activation by Ovalbumin Immunization with a Monophosphoryl Lipid A and Poly I:C Combination Adjuvant Promoted Dendritic Cell Maturation CT Le, SY Ahn, SM Kang, EJ Ko	Human vaccines	2021
Heterodimeric IL-15 in Cancer Immunotherapy C Bergamaschi, V Stravokefalou, D Stellas, S Karaliota, BK Felber, GN Pavlakis	Cancers	2021
AI-guided discovery of the invariant host response to viral pandemics D Sahoo, GD Katkar, S Khandelwal, M Behroozikhah, A Claire, V Castillo, C Tindle, MK Fuller, S Taheri, TF Rogers, N Beutler, SI Ramirez, SA Rawlings, V Pretorius, DM Smith, DR Burton, LE Alexander, J Duran, S Crotty, JM Dan, S Das, P Ghosh	EBioMedicine	2021
Cbl-b Is Upregulated and Plays a Negative Role in Activated Human NK Cells T Lu, L Chen, AG Mansour, MJ Yu, N Brooks, KY Teng, Z Li, J Zhang, T Barr, J Yu, MA Caligiuri	Journal of immunology (Baltimore, Md. : 1950)	2021
Seven interferon gamma response genes serve as a prognostic risk signature that correlates with immune infiltration in lung adenocarcinoma B Yao, L Wang, H Wang, J Bao, Q Li, F Yu, W Zhu, L Zhang, W Li, Z Gu, K Fei, P Zhang, F Zhang, X Huang	Aging	2021
Sesamolin promotes cytolysis and migration activity of natural killer cells via dendritic cells JK Lee	Archives of Pharmacal Research	2020
Monocytes and the Host Response to Fungal Pathogens LJ Heung	Frontiers in Cellular and Infection Microbiology	2020
Cloning and functional characterisation of natural killer enhancing factor-B (NKEF-B) gene of Labeo rohita: Anti-oxidant and antimicrobial activities of its recombinant protein S Parida, A Mohapatra, PK Sahoo	Molecular Immunology	2020
IL-15 enhances the capacity of primary human macrophages to control Leishmania braziliensis infection by IL-32/vitamin D dependent and independent pathways LL de Lima Silva, RS Gomes, MV Silva, LA Joosten, F Ribeiro-Dias	Parasitology International	2020
Cellular, Molecular, and Immunological Characteristics of Langhans Multinucleated Giant Cells Programmed by IL-15 H Wang, H Jiang, RM Teles, Y Chen, A Wu, J Lu, Z Chen, F Ma, M Pellegrini, RL Modlin	Journal of Investigative Dermatology	2020
Fueling Cancer Immunotherapy With Common Gamma Chain Cytokines CJ Dwyer, HM Knochelmann, AS Smith, MM Wyatt, GO Rivera, DC Arhontoulis, E Bartee, Z Li, MP Rubinstein, CM Paulos	Frontiers in immunology	2019
Cytokines: Key Determinants of Resistance or Disease Progression in Visceral Leishmaniasis: Opportunities for Novel Diagnostics and Immunotherapy A Dayakar, S Chandrasekaran, SV Kuchipudi, SK Kalangi	Frontiers in immunology	2019
Activation of Human NK Cells by Bordetella pertussis Requires Inflammasome Activation in Macrophages MM Kroes, R Mariman, D Hijdra, HJ Hamstra, KJ van Boxtel, JP van Putten, J de Wit, E Pinelli	Frontiers in immunology	2019
Patrolling Monocytes Control NK Cell Expression of Activating and Stimulatory Receptors to Curtail Lung Metastases PB Narasimhan, T Eggert, YP Zhu, P Marcovecchio, MA Meyer, R Wu, CC Hedrick	Journal of immunology (Baltimore, Md. : 1950)	2019
Identification and functional characterization of a g-type lysozyme gene of Labeo rohita, an Indian major carp species A Mohapatra, S Parida, J Mohanty, PK Sahoo	Developmental and comparative immunology	2019
IFNG-AS1 Enhances Interferon Gamma Production in Human Natural Killer Cells N Stein, O Berhani, D Schmiedel, A Duev-Cohen, E Seidel, I Kol, P Tsukerman, M Hecht, A Reches, M Gamliel, A Obeidat, Y Charpak-Amikam, R Yamin, O Mandelboim	iScience	2019
Hepatic Tumor Microenvironments and Effects on NK Cell Phenotype and Function JP Fernández, KA Luddy, C Harmon, C OFarrelly	International journal of molecular sciences	2019
Human natural killer cells for targeting delivery of gold nanostars and bimodal imaging directed photothermal/photodynamic therapy and immunotherapy Bin Liu, Wen Cao, Jin Cheng, Sisi Fan, Shaojun Pan, Lirui Wang, Jiaqi Niu, Yunxiang Pan, Yanlei Liu, Xiyang Sun, Lijun Ma, Jie Song, Jian Ni, Daxiang Cui	Cancer biology & medicine	2019
The Interferon-Gamma Paradox in Cancer MR Zaidi	Journal of Interferon & Cytokine Research	2018
Interferon-Gamma at the Crossroads of Tumor Immune Surveillance or Evasion F Castro, AP Cardoso, RM Gonçalves, K Serre, MJ Oliveira	Frontiers in immunology	2018
Mechanisms regulating expansion of CD8+ T cells during HIV-1 infection A Nasi, F Chiodi	Journal of Internal Medicine	2018
Conjunctival Inflammatory Gene Expression Profiling in Dry Eye Disease: Correlations With HLA-DRA and HLA-DRB1 K Kessal, H Liang, G Rabut, P Daull, JS Garrigue, M Docquier, SM Parsadaniantz, C Baudouin, F Brignole-Baudouin	Frontiers in immunology	2018
Frequencies of IL-15Rα+ cells in patients with Behçet’s disease and the effects of overexpressing IL-15Rα+ on disease symptoms in mice SM Islam, B Choi, J Choi, ES Lee, S Sohn	Cytokine	2018
Molecular characterization and expression analysis of interleukin 15 (IL15) and interleukin-15 receptor subunit alpha (IL15Rα) in dojo loach (Misgurnus anguillicaudatus): Their salient roles during bacterial, parasitic and fungal infection X Chen, W Kong, Y Yu, S Dong, Z Huang, W Yu, J Xu, Y Luo, Q Wang, Z Xu	Molecular Immunology	2018
MICA-Expressing Monocytes Enhance Natural Killer Cell Fc Receptor-Mediated Antitumor Functions AR Campbell, MC Duggan, LP Suarez-Kelly, N Bhave, KS Opheim, EL McMichael, P Trikha, R Parihar, E Luedke, A Lewis, B Yung, R Lee, D Raulet, S Tridandapani, V Groh, L Yu, V Yildiz, JC Byrd, MA Caligiuri, WE Carson	Cancer immunology research	2017
The potential and promise of IL-15 in immuno-oncogenic therapies TO Robinson, KS Schluns	Immunology Letters	2017
Pro- and anti-inflammatory cytokines in cutaneous leishmaniasis: a review N Maspi, A Abdoli, F Ghaffarifar	Pathogens and Global Health	2016
TLR2 signals via NF-κB to drive IL-15 production in salivary gland epithelial cells derived from patients with primary Sjögren’s syndrome M Sisto, L Lorusso, S Lisi	Clinical and Experimental Medicine	2016
Higher Type 1 Interferon Levels in Plasma of Asymptomatic HIV-2 than in HIV-1 Individuals SV Nuvor, H Whittle, S Rowland-Jones, A Jaye	Advances in Infectious Diseases	2016
Novel Immunotherapeutic Approaches to the Treatment of Cancer S Ranganath, AC Nguyen	Novel Immunotherapeutic Approaches to the Treatment of Cancer	2016
Identification of IFN-γ-producing T cells as the main mediators of the side effects associated to mouse interleukin-15 sustained exposure MD Scala, I Gil-Fariña, C Olagüe, A Vales, L Sobrevals, P Fortes, D Corbacho, G González-Aseguinolaza	Oncotarget	2016
Molecular characterization of interleukin 15 mRNA from rohu, Labeo rohita (Hamilton): Its prominent role during parasitic infection as indicated from infection studies S Das, A Mohapatra, B Kar, PK Sahoo	Fish & Shellfish Immunology	2015
Effect of total flavonoids from the seeds of Astragali complanati on natural killer cell function R Han, WQ Wu, XP Wu, CY Liu	Journal of Ethnopharmacology	2015
Molecular Pathways: Interleukin-15 Signaling in Health and in Cancer A Mishra, L Sullivan, MA Caligiuri	Clinical cancer research	2014
Clinical utility of natural killer cells in cancer therapy and transplantation DA Knorr, V Bachanova, MR Verneris, JS Miller	Seminars in Immunology	2014
Notch Signaling at Later Stages of NK Cell Development Enhances KIR Expression and Functional Maturation M Felices, DE Ankarlo, TR Lenvik, HH Nelson, BR Blazar, MR Verneris, JS Miller	Journal of immunology (Baltimore, Md. : 1950)	2014
Human monocytes have increased IFN-γ-mediated IL-15 production with age alongside altered IFN-γ receptor signaling N Lee, MS Shin, KS Kang, SA Yoo, S Mohanty, RR Montgomery, AC Shaw, I Kang	Clinical Immunology	2014
T cell interleukin-15 surface expression in chimpanzees infected with human immunodeficiency virus AR Rodriguez, V Hodara, K Murthy, LS Morrow, M Sanchez, AE Bienvenu, KK Murthy	Cellular Immunology	2014
A promoter polymorphism (rs3806798) of interleukin-15 gene is associated with chronic hepatitis B virus infection in the Chinese Han population X Zhang, XH Sun, M Li, ZH Zhou, YQ Gao	International Journal of Immunogenetics	2014
The Absence or Overexpression of IL-15 Drastically Alters Breast Cancer Metastasis via Effects on NK Cells, CD4 T Cells, and Macrophages A Gillgrass, N Gill, A Babian, AA Ashkar	Journal of immunology (Baltimore, Md. : 1950)	2014
Human cord blood γδ T cells expressing public Vγ2 chains dominate the response to bisphosphonate plus interleukin-15 C Cairo, B Sagnia, G Cappelli, V Colizzi, RG Leke, RJ Leke, CD Pauza	Immunology	2013
Location and cellular stages of natural killer cell development J Yu, AG Freud, MA Caligiuri	Trends in Immunology	2013
The role of IL15 gene variants in visceral leishmaniasis among Iranian patients M Rasouli, M Kalani, S Kiany	Molecular Biology Reports	2013
IFN-γ production by human natural killer cells in response to HCV-infected hepatoma cells is dependent on accessory cells S Zhang, B Saha, K Kodys, G Szabo	Journal of Hepatology	2013
Effect of IL-15 and Natural Killer Cells on Osteoclasts and Osteoblasts in a Mouse Coculture H Takeda, T Kikuchi, K Soboku, I Okabe, H Mizutani, A Mitani, Y Ishihara, T Noguchi	Inflammation	2013
Effect of Hibisci Flos on Inflammatory Cytokines Production in lipopolysaccaride-stimulated Raw 264.7 Macrophages DM Lee, HS Han, YJ Lee	The Korea Journal of Herbology	2013
Soluble MICA-NKG2D interaction upregulates IFN-γ production by activated CD3−CD56+ NK cells: Potential impact on chronic graft versus host disease W Boukouaci, R Al-Daccak, N Dulphy, L Lauden, K Amokrane, C Fortier, F Marzais, M Bennabi, RP de Latour, G Socie, A Toubert, D Charron, R Krishnamoorthy, R Tamouza	Human Immunology	2013
Production of Bioactive Soluble Interleukin-15 in Complex with Interleukin-15 Receptor Alpha from a Conditionally-Replicating Oncolytic HSV-1 DC Gaston, CI Odom, L Li, JM Markert, JC Roth, KA Cassady, RJ Whitley, JN Parker, B Lichty	PloS one	2013
Vaccine Development Against Leishmania donovani A Das, N Ali	Frontiers in immunology	2012
Expression of Interleukin-15 and Interleukin-15Rα in Monocytes of HIV Type 1-Infected Patients with Different Courses of Disease Progression M Tarkowski, L Ferraris, S Martone, FS de Castillia, D Misciagna, RI Mazzucchelli, E Lattuada, G Paraninfo, M Galli, A Riva	AIDS Research and Human Retroviruses	2012
The Cytokine Network of Acute HIV Infection: A Promising Target for Vaccines and Therapy to Reduce Viral Set-Point? PD Katsikis, YM Mueller, F Villinger	PLoS pathogens	2011
NK cells: immune cross-talk and therapeutic implications A Malhotra, A Shanker	Immunotherapy	2011
Interleukin (IL)-15 in combination with IL-2, fms-like tyrosine kinase-3 ligand and anti-CD3 significantly enhances umbilical cord blood natural killer (NK) cell and NK-cell subset expansion and NK function P Satwani, C de Ven, J Ayello, D Cairo, LL Simpson, L Baxi, MS Cairo	Cytotherapy	2011
Interleukin 15 as a promising candidate for tumor immunotherapy M Jakobisiak, J Golab, W Lasek	Cytokine & Growth Factor Reviews	2011
The role of IL-15 in central nervous system disorders M Rentzos, A Rombos	Acta Neurologica Scandinavica	2011
Evaluating the role of IL-12 based therapies in ovarian cancer: a review of the literature JM Whitworth, RD Alvarez	Expert Opinion on Biological Therapy	2011
Stimulating natural killer cells to protect against cancer: recent developments A Gillgrass, A Ashkar	Expert Review of Clinical Immunology	2011
Advances in Immunology E Pinaud, M Marquet, R Fiancette, S Péron, C Vincent-Fabert, Y Denizot, M Cogné	Advances in Immunology Volume 110	2011
Vaccination of Mice with ORF5 Plasmid DNA of PRRSV; Enhanced Effects by Co-immunizing with Porcine IL-15 G Li, N Shi, S Suo, J Cui, D Zarlenga, X Ren	Immunological Investigations	2011
Natural Killer (NK) Cells in Antibacterial Innate Immunity: Angels or Devils? F Souza-Fonseca-Guimaraes, M Adib-Conquy, JM Cavaillon	Molecular Medicine	2011
Henry's Clinical Diagnosis and Management by Laboratory Methods JL Miller, AK Rao	Henry's Clinical Diagnosis and Management by Laboratory Methods	2011
The Cytokine Network of Acute HIV Infection: A Promising Target for Vaccines and Therapy to Reduce Viral Set-Point? PD Katsikis, YM Mueller, F Villinger, M Manchester	PLoS pathogens	2011
The Role of IL-15 Deficiency in the Pathogenesis of Virus-Induced Asthma Exacerbations V Laza-Stanca, SD Message, MR Edwards, HL Parker, MT Zdrenghea, T Kebadze, OM Kon, P Mallia, LA Stanciu, SL Johnston, JU Jung	PLoS pathogens	2011
Contribution of astrocyte-derived IL-15 to CD8 T cell effector functions in multiple sclerosis P Saikali, JP Antel, CL Pittet, J Newcombe, N Arbour	Journal of immunology (Baltimore, Md. : 1950)	2010
Natural Killer Cell–Mediated Cytokine Response Among HIV-Positive South Indians With Pulmonary Tuberculosis PV Rao, S Rajasekaran, A Raja	Journal of Interferon & Cytokine Research	2010
An Accessory Role for B Cells in the IL-12-Induced Activation of Resting Mouse NK Cells EA Haddad, LK Senger, F Takei	Journal of immunology (Baltimore, Md. : 1950)	2009
Exposure to cigarette smoke suppresses IL-15 generation and its regulatory NK cell functions in poly I:C-augmented human PBMCs MF Mian, EA Pek, KL Mossman, MR Stämpfli, AA Ashkar	Molecular Immunology	2009
Effect of interleukin-15 on the course of myocarditis in Coxsackievirus B3-infected BALB/c mice B Bigalke, PL Schwimmbeck, CS Haas, S Lindemann	Canadian Journal of Cardiology	2009
Chronic bacterial osteomyelitis suppression of tumor growth requires innate immune responses JL Sottnik, LW U’Ren, DH Thamm, SJ Withrow, SW Dow	Cancer Immunology, Immunotherapy	2009
Influence of testosterone and a novel SARM on gene expression in whole blood of Macaca fascicularis I Riedmaier, A Tichopad, M Reiter, MW Pfaffl, HH Meyer	The Journal of Steroid Biochemistry and Molecular Biology	2009
A Programmed Switch from IL-15- to IL-2-Dependent Activation in Human NK Cells AH Pillet, F Bugault, J Thèze, LA Chakrabarti, T Rose	Journal of immunology (Baltimore, Md. : 1950)	2009
Interleukin-15 and NK1.1 + Cells Provide Innate Protection against Acute Salmonella enterica Serovar Typhimurium Infection in the Gut and in Systemic Tissues AA Ashkar, S Reid, EF Verdu, K Zhang, BK Coombes	Infection and immunity	2009
Effect of interleukin-15 on the course of myocarditis in Coxsackievirus B3-infected BALB/c mice. Bigalke B, Schwimmbeck PL, Haas CS, Lindemann S	The Canadian journal of cardiology	2009
Association between interleukin-15 and obesity: interleukin-15 as a potential regulator of fat mass AR Nielsen, P Hojman, C Erikstrup, CP Fischer, P Plomgaard, R Mounier, OH Mortensen, C Broholm, S Taudorf, R Krogh-Madsen, B Lindegaard, AM Petersen, J Gehl, BK Pedersen	The Journal of clinical endocrinology and metabolism	2008
Immunology		2008
Requirement of TLR2-mediated signaling for the induction of IL-15 gene expression in human monocytic cells by HSV-1 R Ahmad, SE Bassam, P Cordeiro, J Menezes	Blood	2008
Augumentation of Natural Killer Activity with Exogenous Interleukins in Patients with HIV and Pulmonary Tuberculosis Coinfection PV Rao, S Rajasekaran, A Raja	AIDS Research and Human Retroviruses	2008
The number and function of circulating dendritic cells may limit effector memory CD4+ T-cell responses in HIV patients responding to antiretroviral therapy S Fernandez, SF Stone, P Price, MA French	Clinical Immunology	2008
Interleukin-15 increases Paracoccidioides brasiliensis killing by human neutrophils EG Tavian, LA Dias-Melicio, MJ Acorci, AP Graciani, MT Peraçoli, AM de Soares	Cytokine	2008
Membrane bound IL-15 is increased on CD14 monocytes in early stages of MS A Vaknin-Dembinsky, SD Brass, S Brass, R Gandhi, HL Weiner	Journal of Neuroimmunology	2008
Trogocytosis and killing of IL-4-polarized monocytes by autologous NK cells M Poupot, JJ Fournié, R Poupot	Journal of leukocyte biology	2008
NK Cells Play a Critical Protective Role in Host Defense against Acute Extracellular Staphylococcus aureus Bacterial Infection in the Lung CL Small, S McCormick, N Gill, K Kugathasan, M Santosuosso, N Donaldson, DE Heinrichs, A Ashkar, Z Xing	Journal of immunology (Baltimore, Md. : 1950)	2008
An Unusual CD56 bright CD16 low NK Cell Subset Dominates the Early Posttransplant Period following HLA-Matched Hematopoietic Stem Cell Transplantation N Dulphy, P Haas, M Busson, S Belhadj, RP de Latour, M Robin, M Carmagnat, P Loiseau, R Tamouza, C Scieux, C Rabian, JP Santo, D Charron, A Janin, G Socié, A Toubert	Journal of immunology (Baltimore, Md. : 1950)	2008
Interaction of Monocytes with NK Cells upon Toll-Like Receptor-Induced Expression of the NKG2D Ligand MICA M Kloss, P Decker, KM Baltz, T Baessler, G Jung, HG Rammensee, A Steinle, M Krusch, HR Salih	Journal of immunology (Baltimore, Md. : 1950)	2008
IL-15 Links TLR2/1-Induced Macrophage Differentiation to the Vitamin D-Dependent Antimicrobial Pathway SR Krutzik, M Hewison, PT Liu, JA Robles, S Stenger, JS Adams, RL Modlin	Journal of immunology (Baltimore, Md. : 1950)	2008
Prolonged, NK cell-mediated antitumor effects of suicide gene therapy combined with monocyte chemoattractant protein-1 against hepatocellular carcinoma T Tsuchiyama, Y Nakamoto, Y Sakai, Y Marukawa, M Kitahara, N Mukaida, S Kaneko	Journal of immunology (Baltimore, Md. : 1950)	2007
Cell-specific interleukin-15 and interleukin-15 receptor subunit expression and regulation in pneumococcal pneumonia--comparison to chlamydial lung infection AC Hocke, MP Lampe, M Witzenrath, H Mollenkopf, J Zerrahn, B Schmeck, U Kessler, M Krüll, S Hammerschmidt, S Hippenstiel, H Schütte, N Suttorp, S Rosseau	Cytokine	2007
Mycobacterium tuberculosis -Induced Gamma Interferon Production by Natural Killer Cells Requires Cross Talk with Antigen-Presenting Cells Involving Toll-Like Receptors 2 and 4 and the Mannose Receptor in Tuberculous Pleurisy P Schierloh, N Yokobori, M Alemán, V Landoni, L Geffner, RM Musella, J Castagnino, M Baldini, E Abbate, SS de la Barrera, MC Sasiain	Infection and immunity	2007
Gr-1 high Polymorphonuclear Leukocytes and NK Cells Act via IL-15 to Clear Intracellular Haemophilus influenzae in Experimental Murine Peritonitis and Pneumonia S Miyazaki, F Ishikawa, K Shimizu, T Ubagai, PH Edelstein, K Yamaguchi	Journal of immunology (Baltimore, Md. : 1950)	2007
Molecular and Functional Characterization of IL-15 in Rainbow Trout Oncorhynchus mykiss: A Potent Inducer of IFN-γ Expression in Spleen Leukocytes T Wang, JW Holland, A Carrington, J Zou, CJ Secombes	Journal of immunology (Baltimore, Md. : 1950)	2007
Utilizing IL-12, IL-15 and IL-7 as Mucosal Vaccine Adjuvants L Stevceva, M Moniuszko, MG Ferrari	Letters in drug design & discovery	2006
Cytokine profile during latent and slowly progressive primary tuberculosis: a possible role for interleukin-15 in mediating clinical disease F Abebe, T Mustafa, AH Nerland, GA Bjune	Clinical & Experimental Immunology	2006
Interleukin-15 rescues tolerant CD8+ T cells for use in adoptive immunotherapy of established tumors RM Teague, BD Sather, JA Sacks, MZ Huang, ML Dossett, J Morimoto, X Tan, SE Sutton, MP Cooke, C Öhlén, PD Greenberg	Nature Medicine	2006
Regulation by GD3 of the proinflammatory response of microglia mediated by interleukin-15 D Gómez-Nicola, E Doncel-Pérez, M Nieto-Sampedro	Journal of Neuroscience Research	2006
Natural killer cells: Primary target for hepatitis C virus immune evasion strategies? L Golden-Mason, HR Rosen	Liver Transplantation	2006
Levels of IL-15 in Serum and Cerebrospinal Fluid of Patients with Beh�et's Disease K Hamzaoui, A Hamzaoui, I Ghorbel, M Khanfir, H Houman	Scandinavian Journal of Immunology	2006
Modulation of Immune Responses Induced by DNA Vaccine Expressing Glycoprotein B of Pseudorabies Virus via Coadministration of IFN-γ-Associated Cytokines HA Yoon, AG Aleyas, JA George, SO Park, YW Han, JH Lee, HY Kang, SH Kang, JG Cho, SK Eo	Journal of Interferon & Cytokine Research	2006
Human natural killer cell development and biology SS Farag, MA Caligiuri	Blood Reviews	2006
Two interleukin (IL)-15 homologues in fish from two distinct origins JX Bei, H Suetake, K Araki, K Kikuchi, Y Yoshiura, HR Lin, Y Suzuki	Molecular Immunology	2006
The innate interferon gamma response of BALB/c and C57BL/6 mice to in vitro Burkholderia pseudomallei infection GC Koo, YH Gan	BMC Immunology	2006
IL-15 is elevated in serum and cerebrospinal fluid of patients with multiple sclerosis M Rentzos, C Cambouri, A Rombos, C Nikolaou, M Anagnostouli, A Tsoutsou, A Dimitrakopoulos, N Triantafyllou, D Vassilopoulos	Journal of the Neurological Sciences	2006
Interaction of monocytic cells with respiratory syncytial virus results in activation of NF-κB and PKC-α/β leading to up-regulation of IL-15 gene expression J Ennaciri, R Ahmad, J Menezes	Journal of leukocyte biology	2006
Impaired Protection against Mycobacterium bovis Bacillus Calmette-Guérin Infection in IL-15-Deficient Mice K Saito, T Yajima, S Kumabe, T Doi, H Yamada, S Sad, H Shen, Y Yoshikai	Journal of immunology (Baltimore, Md. : 1950)	2006
NK cell activity in tuberculosis is associated with impaired CD11a and ICAM-1 expression: a regulatory role of monocytes in NK activation P Schierloh, M Alemán, N Yokobori, L Alves, N Roldán, E Abbate, MC Sasiain, S la Barrera	Immunology	2005
Human CD56bright and CD56dim Natural Killer Cell Subsets Respond Differentially to Direct Stimulation with Mycobacterium bovis Bacillus Calmette-Guerin G Batoni, S Esin, F Favilli, M Pardini, D Bottai, G Maisetta, W Florio, M Campa	Scandinavian Journal of Immunology	2005
Signaling T-Cell Survival and Death by IL-2 and IL-15 E Zambricki, A Shigeoka, H Kishimoto, J Sprent, S Burakoff, C Carpenter, E Milford, D McKay	American Journal of Transplantation	2005
Herpesviruses and the Innate Immune Response KL Mossman, AA Ashkar	Viral Immunology	2005
Effects of interleukin-15 on antifungal responses of human polymorphonuclear leukocytes against Fusarium spp. and Scedosporium spp RM Winn, C Gil-Lamaignere, E Roilides, M Simitsopoulou, CA Lyman, A Maloukou, TJ Walsh	Cytokine	2005
A high-efficiency system of natural killer cell cloning RJ Morris, LK Chong, GW Wilkinson, EC Wang	Journal of Immunological Methods	2005
Inhibition of lymphocyte apoptosis by pancreatic stellate cells: impact of interleukin-15 G Sparmann, Ä Glass, P Brock, R Jaster, D Koczan, HJ Thiesen, S Liebe, J Emmrich	AJP Gastrointestinal and Liver Physiology	2005
Cytokines, chemokines and growth factors in endometrium related to implantation E Dimitriadis, CA White, RL Jones, LA Salamonsen	Human Reproduction Update	2005
Biophysical Aspects of Transmembrane Signaling S Damjanovich		2005
Dysregulation of Expression of Immunoregulatory and Cytokine Genes and Its Association with the Immaturity in Neonatal Phagocytic and Cellular Immunity P Satwani, E Morris, C van de Ven, MS Cairo	Neonatology	2005
Ligands for natural killer cell–activating receptors are expressed upon the maturation of normal myelomonocytic cells but at low levels in acute myeloid leukemias P Nowbakht, MC Ionescu, A Rohner, CP Kalberer, E Rossy, L Mori, D Cosman, GD Libero, A Wodnar-Filipowicz	Blood	2005
Heterogeneity of TLR-induced responses in dendritic cells: from innate to adaptive immunity F Re, JL Strominger	Immunobiology	2004
IL-12 Pretreatments Enhance IFN-α-Induced Janus Kinase-STAT Signaling and Potentiate the Antitumor Effects of IFN-α in a Murine Model of Malignant Melanoma GB Lesinski, B Badgwell, J Zimmerer, T Crespin, Y Hu, G Abood, WE Carson	Journal of immunology (Baltimore, Md. : 1950)	2004
Interleukin-15, as Interferon-gamma, Induces the Killing of Leishmania infantum in Phorbol-Myristate-Acetate-Activated Macrophages Increasing Interleukin-12 P D'Agostino, S Milano, F Arcoleo, GD Bella, ML Rosa, V Ferlazzo, R Caruso, N Chifari, G Vitale, S Mansueto, E Cillari	Scandinavian Journal of Immunology	2004
Hepatic interleuklin 15 (IL-15) expression: implications for local NK/NKT cell homeostasis and development L Golden-Mason, AM Kelly, DG Doherty, O Traynor, G McEntee, J Kelly, JE Hegarty, C O'Farrelly	Clinical & Experimental Immunology	2004
Induction and Regulation of IFNs During Viral Infections L Malmgaard	Journal of Interferon & Cytokine Research	2004
The Regulation and Activation of CD44 by Natural Killer (NK) Cells and Its Role in the Production of IFN-γ SL Sague, C Tato, E Puré, CA Hunter	Journal of Interferon & Cytokine Research	2004
Combined activation of innate and T cell immunity for recognizing immunomodulatory properties of therapeutic agents B Rose, C Herder, H Löffler, H Kolb, S Martin	Journal of leukocyte biology	2004
Interleukin-15 Enhances Cytotoxicity, Receptor Expression, and Expansion of Neonatal Natural Killer Cells in Long-Term Culture SS Choi, VS Chhabra, QH Nguyen, BJ Ank, ER Stiehm, RL Roberts	Clinical and vaccine immunology : CVI	2004
Cytokines and Joint Injury WB van den Berg, P Miossec		2004
Mature dendritic cells can enhance CD8+ cell noncytotoxic anti-HIV responses: the role of IL-15 JA Castelli, EK Thomas, M Gilliet, YJ Liu, JA Levy	Blood	2004
Overexpression of Interleukin-15 Increases Susceptibility to Lipopolysaccharide-Induced Liver Injury in Mice Primed with Mycobacterium bovis Bacillus Calmette-Guérin T Yajima, H Nishimura, K Saito, H Kuwano, Y Yoshikai	Infection and immunity	2004
IL-10 Released by Concomitant TLR2 Stimulation Blocks the Induction of a Subset of Th1 Cytokines That Are Specifically Induced by TLR4 or TLR3 in Human Dendritic Cells F Re, JL Strominger	Journal of immunology (Baltimore, Md. : 1950)	2004
CD56 + Cells Induce Steroid Resistance in B Cells Exposed to IL-15 Q Xu, E Goleva, LS Ou, LB Li, DY Leung	Journal of immunology (Baltimore, Md. : 1950)	2004
Recombinant gamma interferon stimulates signal transduction and gene expression in alveolar macrophages in vitro and in tuberculosis patients R Condos, B Raju, A Canova, BY Zhao, M Weiden, WN Rom, R Pine	Infection and immunity	2003
Cytokine control of memory T-cell development and survival KS Schluns, L Lefrançois	Nature Reviews Immunology	2003
Interferon (IFN)-α/β, interleukin (IL)-12 and IL-18 coordinately induce production of IFN-γ during infection with herpes simplex virus type 2 L Malmgaard, SR Paludan	Journal of General Virology	2003
HIV-1 matrix protein p17 enhances the proliferative activity of natural killer cells and increases their ability to secrete proinflammatory cytokines M Vitale, A Caruso, MA de Francesco, L Rodella, L Bozzo, E Garrafa, M Grassi, G Gobbi, A Cacchioli, S Fiorentini	British Journal of Haematology	2003
The innate immune response in calves to Boophilus microplus tick transmitted Babesia bovis involves type-1 cytokine induction and NK-like cells in the spleen WL Goff, WC Johnson, RH Horn, GM Barrington, DP Knowles	Parasite Immunology	2003
Host's innate immune response to fungal and bacterial agents in vitro: up-regulation of interleukin-15 gene expression resulting in enhanced natural killer cell activity P Tran, R Ahmad, J Xu, A Ahmad, J Menezes	Immunology	2003
Cytokine Tissue Levels as Markers of Disease Activity in Pediatric Crohn Disease MA Silva, J Menezes, S Wizman, R Gendron, L Oligny, EG Seidman	Pediatric Research	2003
Interleukin 12 in Part Regulates Gamma Interferon Release in Human Whole Blood Stimulated with Leptospira interrogans M de Fost, RA Hartskeerl, MR Groenendijk, T van der Poll	Clinical and vaccine immunology : CVI	2003
IL-15 induces antigen-independent expansion and differentiation of human naive CD8+ T cells in vitro NL Alves, B Hooibrink, FA Arosa, RA van Lier	Blood	2003
Studies on the production of IL-15 in HIV-infected/AIDS patients Rasheed Ahmad, Sardar T A Sindhu, Emil Toma, Richard Morisset, Ali Ahmad	Journal of Clinical Immunology	2003
Natural killer lymphocytes: biology, development, and function Papamichail M, Perez SA, Gritzapis AD, Baxevanis CN	Cancer Immunology, Immunotherapy	2003
In vivo evidence for a dependence on interleukin 15 for survival of natural killer cells MA Cooper, JE Bush, TA Fehniger, JB VanDeusen, RE Waite, Y Liu, HL Aguila, MA Caligiuri	Blood	2002
Host Resistance in the Brain againstToxoplasma gondii Y Suzuki	The Journal of Infectious Diseases	2002
Type I Interferon Production by Plasmacytoid Dendritic Cells and Monocytes Is Triggered by Viruses, but the Level of Production Is Controlled by Distinct Cytokines H Gary-Gouy, P Lebon, AH Dalloul	Journal of Interferon & Cytokine Research	2002
IL-15 Is a Growth Factor and an Activator of CD8 Memory T Cells NP Weng, K Liu, M Catalfamo, Y Li, PA Henkart	Annals of the New York Academy of Sciences	2002
IL-15 in human visceral leishmaniasis caused by Leishmania infantum S Milano, GD Bella, P D'Agostino, C Barbera, R Caruso, ML Rosa, V Ferlazzo, G Vitale, CL Russa, G Gambino, N Chifari, S Mansueto, E Cillari	Clinical & Experimental Immunology	2002
Induction of IL-15 by TCR/CD3 aggregation depends on IFN-gamma and protects against apoptosis of immature thymocytes in vivo P Matthys, H Dooms, P Rottiers, T Mitera, L Overgergh, G Leclercq, A Billiau, J Grooten	Clinical & Experimental Immunology	2002
Differential expression of interleukins (IL) IL-13 and IL-15 throughout the menstrual cycle in endometrium of normal fertile women and women with recurrent spontaneous abortion N Chegini, C Ma, M Roberts, RS Williams, BA Ripps	Journal of Reproductive Immunology	2002
Quantitation of natural killer cell precursors in man A Gharehbaghian, KM Haque, C Truman, J Newman, BA Bradley	Journal of Immunological Methods	2002
Development and characterization of monoclonal antibodies to chicken interleukin-15 W Min, HS Lillehoj, G Li, EJ Sohn, T Miyamoto	Veterinary Immunology and Immunopathology	2002
The contrasting roles of IL-2 and IL-15 in the life and death of lymphocytes: implications for the immunotherapy of rheumatological diseases T Waldmann	Arthritis research	2002
Comprehensive gene expression analysis of human NK cells and CD8+ T lymphocytes A Obata-Onai, S Hashimoto, N Onai, M Kurachi, S Nagai, K Shizuno, T Nagahata, K Matsushima	International Immunology	2002
Decreased IL-15 may contribute to elevated IgE and acute inflammation in atopic dermatitis PY Ong, QA Hamid, JB Travers, I Strickland, MA Kerithy, M Boguniewicz, DY Leung	Journal of immunology (Baltimore, Md. : 1950)	2002
Administration of two macrophage-derived interferon-γ-inducing factors (IL-12 and IL-15) induces a lethal systemic inflammatory response in mice that is dependent on natural killer cells but does not require interferon-γ JL Biber, S Jabbour, R Parihar, J Dierksheide, Y Hu, H Baumann, P Bouchard, MA Caligiuri, W Carson	Cellular Immunology	2002
Regulatory pathways involved in the infection-induced production of IFN-γ by NK cells LA Lieberman, CA Hunter	Microbes and Infection	2002
Activation of Human NK Cells by Staphylococci and Lactobacilli Requires Cell Contact-Dependent Costimulation by Autologous Monocytes D Haller, P Serrant, D Granato, EJ Schiffrin, S Blum	Clinical and vaccine immunology : CVI	2002
Overexpression of interleukin-15in vivo enhances antitumor activity against mhc class I-negative and -positive malignant melanoma through augmented NK activity and cytotoxic T-cell response T Yajima, H Nishimura, W Wajjwalku, M Harada, H Kuwano, Y Yoshikai	International Journal of Cancer	2002
CD8 T Cell-Mediated Killing of Cryptococcus neoformans Requires Granulysin and Is Dependent on CD4 T Cells and IL-15 LL Ma, JC Spurrell, JF Wang, GG Neely, S Epelman, AM Krensky, CH Mody	Journal of immunology (Baltimore, Md. : 1950)	2002
Coordinated and Distinct Roles for IFN-αβ, IL-12, and IL-15 Regulation of NK Cell Responses to Viral Infection KB Nguyen, TP Salazar-Mather, MY Dalod, JB Deusen, X Wei, FY Liew, MA Caligiuri, JE Durbin, CA Biron	Journal of immunology (Baltimore, Md. : 1950)	2002
Endotoxin-Induced Gamma Interferon Production: Contributing Cell Types and Key Regulatory Factors TK Varma, CY Lin, TE Toliver-Kinsky, ER Sherwood	Clinical and vaccine immunology : CVI	2002
Human γδ-T Cells in Adoptive Immunotherapy of Malignant and Infectious Diseases RD Lopez	Immunologic Research	2002
In vivo induction of EBV-specific cellular immunity and protection against EBV-lymphoproliferative disorder with GM-CSF and IL-2 Robert A. Baiocchi, Jacqueline S. Ward, Lester Carrodeguas, Charles Eisenbeis, Ruoqi Peng, Sameek Roychowdhury, Srinivas Vourganti, Taryn Sekula, Maggie O\'Brien, Melvin Moeschberger, Michael A. Caligiuri	Journal of Clinical Investigation	2001
Current Protocols in Immunology EH Leiter	Current Protocols in Immunology	2001
Interleukin 2 and interleukin 15 differentially predispose natural killer cells to apoptosis mediated by endothelial and tumour cells L Rodella, L Zamai, R Rezzani, M Artico, G Peri, M Falconi, A Facchini, G Pelusi, M Vitale	British Journal of Haematology	2001
Interleukin-1β costimulates interferon-γ production by human natural killer cells MA Cooper, TA Fehniger, A Ponnappan, V Mehta, MD Wewers, MA Caligiuri	European Journal of Immunology	2001
Interleukin-2 enhances the natural killer cell response to Herceptin-coated Her2 /neu-positive breast cancer cells WE Carson, R Parihar, MJ Lindemann, N Personeni, J Dierksheide, NJ Meropol, J Baselga, MA Caligiuri	European Journal of Immunology	2001
Immuno-regulatory cytokines in asthma: IL-15 and IL-13 in induced sputum M Komai-Koma, A McKay, L Thomson, C McSharry, GW Chalmers, FY Liew, NC Thomson	Clinical & Experimental Allergy	2001
Inflammation JA Hunt	Encyclopedia of Materials Science and Technology	2001
Cytokine Expression by Murine DX5+ Cells in Response to IL-12, IL-18, or the Combination of IL-12 and IL-18 H Chakir, AM Lemay, JR Webb	Cellular Immunology	2001
Interleukin 15: biology and relevance to human disease TA Fehniger, MA Caligiuri	Blood	2001
Interleukin-12 (IL-12) and IL-18 Are Important in Innate Defense against Genital Herpes Simplex Virus Type 2 Infection in Mice but Are Not Required for the Development of Acquired Gamma Interferon-Mediated Protective Immunity AM Harandi, B Svennerholm, J Holmgren, K Eriksson	Journal of virology	2001
Human Natural Killer Cells Mediate Killing of Intracellular Mycobacterium tuberculosis H37Rv via Granule-Independent Mechanisms SH Kaufmann, KJ Brill, Q Li, R Larkin, DH Canaday, DR Kaplan, WH Boom, RF Silver	Infection and immunity	2001
Overexpression of IL-15 In Vivo Enhances Protection Against Mycobacterium bovis Bacillus Calmette-Guérin Infection Via Augmentation of NK and T Cytotoxic 1 Responses M Umemura, H Nishimura, K Hirose, T Matsuguchi, Y Yoshikai	Journal of immunology (Baltimore, Md. : 1950)	2001
Selective Expansion and Partial Activation of Human NK Cells and NK Receptor-Positive T Cells by IL-2 and IL-15 J Dunne, S Lynch, C OFarrelly, S Todryk, JE Hegarty, C Feighery, DG Doherty	Journal of immunology (Baltimore, Md. : 1950)	2001
Role of CD4 + and CD8 + T Cells in Allorecognition: Lessons from Corneal Transplantation F Boisgérault, Y Liu, N Anosova, E Ehrlich, MR Dana, G Benichou	Journal of immunology (Baltimore, Md. : 1950)	2001
Lipopolysaccharide-Stimulated or Granulocyte-Macrophage Colony-Stimulating Factor-Stimulated Monocytes Rapidly Express Biologically Active IL-15 on Their Cell Surface Independent of New Protein Synthesis GG Neely, SM Robbins, EK Amankwah, S Epelman, H Wong, JC Spurrell, KK Jandu, W Zhu, DK Fogg, CB Brown, CH Mody	Journal of immunology (Baltimore, Md. : 1950)	2001
Enhancement of Human Cord Blood CD34 + Cell-Derived NK Cell Cytotoxicity by Dendritic Cells Y Yu, M Hagihara, K Ando, B Gansuvd, H Matsuzawa, T Tsuchiya, Y Ueda, H Inoue, T Hotta, S Kato	Journal of immunology (Baltimore, Md. : 1950)	2001
Cord Blood Leucocyte Expression of Functionally Significant Molecules Involved in the Regulation of Cellular Immunity: Markers of Cellular Immunity in Cord Blood S Hodge, G Hodge, R Flower, P Han	Scandinavian Journal of Immunology	2001
Cytokine-mediated protection of human dendritic cells from prostate cancer-induced apoptosis is regulated by the Bcl-2 family of proteins G Pirtskhalaishvili, GV Shurin, C Esche, Q Cai, RR Salup, SN Bykovskaia, MT Lotze, MR Shurin	British Journal of Cancer	2000
Human amniotic fluid lacks interleukin-2 and interleukin-15 but can interact with the beta-chain of the interleukin-2 receptor RF Searle, SJ Bromage, J Palmer, JE Curry, AK Lang	Immunology	2000
Eosinophilia with Aberrant T Cells and Elevated Serum Levels of Interleukin-2 and Interleukin-15 M Means-Markwell, T Burgess, D deKeratry, K O'Neil, J Mascola, T Fleisher, D Lucey	New England Journal of Medicine	2000
Inhibition of keratinocyte apoptosis by IL-15: a new parameter in the pathogenesis of psoriasis? R Rückert, K Asadullah, M Seifert, VM Budagian, R Arnold, C Trombotto, R Paus, S Bulfone-Paus	Journal of immunology (Baltimore, Md. : 1950)	2000
The role of interleukin 15 in mounting an immune response against microbial infections Y Yoshikai, H Nishimura	Microbes and Infection	2000
A Protective Role of Interleukin-15 in a Mouse Model for Systemic Infection with Herpes Simplex Virus H Tsunobuchi, H Nishimura, F Goshima, T Daikoku, H Suzuki, I Nakashima, Y Nishiyama, Y Yoshikai	Virology	2000
Epstein-Barr Virus-Infected Natural Killer Cell Leukemia K Akashi, SI Mizuno	Leukemia & Lymphoma	2000
Human Decidual Natural Killer Cells Express the Receptor for and Respond to the Cytokine Interleukin 151 S Verma, SE Hiby, YW Loke, A King	Biology of reproduction	2000
Interleukin-2 enhances the response of natural killer cells to interleukin-12 through up-regulation of the interleukin-12 receptor and STAT4 KS Wang, DA Frank, J Ritz	Blood	2000
Cutting Edge: IL-15 Costimulates the Generalized Shwartzman Reaction and Innate Immune IFN-γ Production In Vivo TA Fehniger, H Yu, MA Cooper, K Suzuki, MH Shah, MA Caligiuri	Journal of immunology (Baltimore, Md. : 1950)	2000
Inhibition of Human NK Cell Function by Valinomycin, a Toxin from Streptomyces griseus in Indoor Air JT Barbieri, A Paananen, R Mikkola, T Sareneva, S Matikainen, M Andersson, I Julkunen, MS Salkinoja-Salonen, T Timonen	Infection and immunity	2000
IL-15 Is Highly Expressed in Inflammatory Bowel Disease and Regulates Local T Cell-Dependent Cytokine Production Z Liu, K Geboes, S Colpaert, GR DHaens, P Rutgeerts, JL Ceuppens	Journal of immunology (Baltimore, Md. : 1950)	2000
Coadministration of interleukin-18 and interleukin-12 induces a fatal inflammatory response in mice: critical role of natural killer cell interferon-γ production and STAT-mediated signal transduction WE Carson, JE Dierksheide, S Jabbour, M Anghelina, P Bouchard, G Ku, H Yu, H Baumann, MH Shah, MA Cooper, J Durbin, MA Caligiuri	Blood	2000
Impaired IFN-γ Production in IFN Regulatory Factor-1 Knockout Mice During Endotoxemia Is Secondary to a Loss of Both IL-12 and IL-12 Receptor Expression CA Salkowski, KE Thomas, MJ Cody, SN Vogel	Journal of immunology (Baltimore, Md. : 1950)	2000
Proinflammatory Effects of IL-10 During Human Endotoxemia FN Lauw, D Pajkrt, CE Hack, M Kurimoto, SJ van Deventer, T van der Poll	Journal of immunology (Baltimore, Md. : 1950)	2000
The interaction of intestinal epithelial cells and intraepithelial lymphocytes in host defense Y Yoshikai	Immunologic Research	1999
IL-15 expression plasmid enhances cell-mediated immunity induced by an HIV-1 DNA vaccine KQ Xin, K Hamajima, S Sasaki, T Tsuji, S Watabe, E Okada, K Okuda	Vaccine	1999
THE MULTIFACETED REGULATION OF INTERLEUKIN-15 EXPRESSION AND THE ROLE OF THIS CYTOKINE IN NK CELL DIFFERENTIATION AND HOST RESPONSE TO INTRACELLULAR PATHOGENS1 TA Waldmann, Y Tagaya	Annual Review of Immunology	1999
NK cells and apoptosis HS Warren, MJ Smyth	Immunology and Cell Biology	1999
Levels of Interleukin-15-Expressing Blood Mononuclear Cells Are Elevated in Multiple Sclerosis Pashenkov, Mustafa, Kivisakk, Link	Scandinavian Journal of Immunology	1999
Immunogene therapy of murine fibrosarcoma using IL-15 gene with high translation efficiency K Kimura, H Nishimura, K Hirose, T Matsuguchi, Y Nimura, Y Yoshikai	European Journal of Immunology	1999
NATURAL KILLER CELLS IN ANTIVIRAL DEFENSE: Function and Regulation by Innate Cytokines CA Biron, KB Nguyen, GC Pien, LP Cousens, TP Salazar-Mather	Annual Review of Immunology	1999
Interleukin-15 as an activator of natural killer cell-mediated antiviral response J Gosselin, A TomoIu, RC Gallo, L Flamand	Blood	1999
Costimulation of human natural killer cells is required for interferon gamma production TA Fehniger, WE Carson, MA Caligiuri	Transplantation Proceedings	1999
Dendritic Cell Secretion of IL-15 Is Induced by Recombinant huCD40LT and Augments the Stimulation of Antigen-Specific Cytolytic T Cells JS Kuniyoshi, CJ Kuniyoshi, AM Lim, FY Wang, ER Bade, R Lau, EK Thomas, JS Weber	Cellular Immunology	1999
Protective Effect of NK1.1+T Cells as Well as NK Cells against Intraperitoneal Tumors in Mice T Kawamura, S Seki, K Takeda, J Narita, Y Ebe, M Naito, H Hiraide, T Abo	Cellular Immunology	1999
Induction of Interleukin-15 Production by HIV-1 Nef Protein: A Role in the Proliferation of Uninfected Cells MG Quaranta, B Camponeschi, E Straface, W Malorni, M Viora	Experimental Cell Research	1999
Molecular and functional characterization of chickenIL-15 KD Choi, HS Lillehoj, KD Song, JY Han	Developmental and comparative immunology	1999
Activation of mononuclear cells by interleukin-12: an in vivo study in chimpanzees F N Lauw, A A te Velde, P E Dekkers, P Speelman, J M Aerts, C E Hack, S J van Deventer, T van der Poll	Journal of Clinical Immunology	1999
Interferon-γ Prevents Apoptosis in Epstein-Barr Virus-Infected Natural Killer Cell Leukemia in an Autocrine Fashion S Mizuno, K Akashi, K Ohshima, H Iwasaki, T Miyamoto, N Uchida, T Shibuya, M Harada, M Kikuchi, Y Niho	Blood	1999
Interleukin-12 Enhances Antifungal Activity of Human Mononuclear Phagocytes against Aspergillus fumigatus : Implications for a Gamma Interferon-Independent Pathway TR Kozel, E Roilides, S Tsaparidou, I Kadiltsoglou, T Sein, TJ Walsh	Infection and immunity	1999
Human Monocytes Constitutively Express Membrane-Bound, Biologically Active, and Interferon-γ–Upregulated Interleukin-15 T Musso, L Calosso, M Zucca, M Millesimo, D Ravarino, M Giovarelli, F Malavasi, AN Ponzi, R Paus, S Bulfone-Paus	Blood	1999
Interleukin 15 is a potent stimulant of intraepithelial lymphocytes EC Ebert	Gastroenterology	1998
Interleukin-2, Interleukin-15, and Their Receptors T Waldmann, Y Tagaya, R Bamford	International Reviews of Immunology	1998
Dysregulation of lymphokine production in the neonate and its impact on neonatal cell mediated immunity Y Suen, S Lee, J Qian, C de Ven, MS Cairo	Vaccine	1998
Interleukin-15, a T-cell growth factor, is expressed in human neural cell lines and tissues J Satoh, K Kurohara, M Yukitake, Y Kuroda	Journal of the Neurological Sciences	1998
Induction of IL-15 mRNA and Protein in A549 Cells by Pro-inflammatory Cytokines M Stoeck, W Kromer, V Gekeler	Immunobiology	1998
Encyclopedia of Immunology RL Riley	Encyclopedia of Immunology	1998
Interleukin-15 as a potential regulator of the innate immune response W Carson, MA Caligiuri	Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas / Sociedade Brasileira de Biofisica ... [et al.]	1998
Induction of cell-mediated immunity during early stages of infection with intracellular protozoa RT Gazzinelli, A Talvani, MM Camargo, HC Santiago, MA Oliveira, LQ Vieira, GA Martins, JC Aliberti, JS Silva	Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas / Sociedade Brasileira de Biofisica ... [et al.]	1998
Interleukin-15 Augments Superoxide Production and Microbicidal Activity of Human Monocytes against Candida albicans N Vázquez, TJ Walsh, D Friedman, SJ Chanock, CA Lyman	Infection and immunity	1998
In Vivo Regulation of Replicative Legionella pneumophila Lung Infection by Endogenous Interleukin-12 JK Brieland, DG Remick, ML LeGendre, NC Engleberg, JC Fantone	Infection and immunity	1998
Regulation and Function of T-Cell-Mediated Immunity during Toxoplasma gondii Infection EY Denkers, RT Gazzinelli	Clinical microbiology reviews	1998
Interleukin-15 May Be Responsible for Early Activation of Intestinal Intraepithelial Lymphocytes after Oral Infection with Listeria monocytogenes in Rats EI Tuomanen, K Hirose, H Suzuki, H Nishimura, A Mitani, J Washizu, T Matsuguchi, Y Yoshikai	Infection and immunity	1998
Effect of interleukin (IL)-12 and IL-15 on activated natural killer (ANK) and antibody-dependent cellular cytotoxicity (ADCC) in HIV infection S J Lin, R L Roberts, B J Ank, Q H Nguyen, E K Thomas, E R Stiehm	Journal of Clinical Immunology	1998
A potential role for interleukin-15 in the regulation of human natural killer cell survival WE Carson, TA Fehniger, S Haldar, K Eckhert, MJ Lindemann, CF Lai, CM Croce, H Baumann, MA Caligiuri	Journal of Clinical Investigation	1997
Examining a paradox in the pathogenesis of human pulmonary tuberculosis: Immune activation and suppression/anergy G Vanham, Z Toossi, CS Hirsch, RS Wallis, SK Schwander, EA Rich, JJ Ellner	Tubercle and Lung Disease	1997
Cloning and Expression of Bovine Interleukin-15: Analysis and Modulation of Transcription by Exogenous Stimulation A Canals, L Gasbarre, P Boyd, S Almeria, D Zarlenga	Journal of Interferon & Cytokine Research	1997
In vitro immunologic and virologic effects of interleukin 15 on peripheral blood mononuclear cells from normal donors and human immunodeficiency virus type 1-infected patients DR Lucey, LA Pinto, FR Bethke, J Rusnak, GP Melcher, FN Hashemi, AL Landay, HA Kessler, RJ Paxton, K Grabstein, GM Shearer	Clinical and diagnostic laboratory immunology	1997
A primer on cytokines: sources, receptors, effects, and inducers JH Curfs, JF Meis, JA Hoogkamp-Korstanje	Clinical microbiology reviews	1997
T CELLS AND OTHER LEUKOCYTES AS MEDIATORS OF IRRITANT CONTACT DERMATITIS RS Kalish	Immunology and Allergy Clinics of North America	1997
Interleukin-15 Promotes Angiogenesisin Vivo AL Angiolillo, H Kanegane, C Sgadari, GH Reaman, G Tosato	Biochemical and Biophysical Research Communications	1997
Interleukin-15 Triggers Activation and Growth of the CD8 T-Cell Pool in Extravascular Tissues of Patients With Acquired Immunodeficiency Syndrome C Agostini, L Trentin, R Sancetta, M Facco, C Tassinari, A Cerutti, M Bortolin, A Milani, M Siviero, R Zambello, G Semenzato	Blood	1997
Decreased Interleukin-15 From Activated Cord Versus Adult Peripheral Blood Mononuclear Cells and the Effect of Interleukin-15 in Upregulating Antitumor Immune Activity and Cytokine Production in Cord Blood JX Qian, S min Lee, Y Suen, E Knoppel, C van de Ven, MS Cairo	Blood	1997
Cytokine-Induced Apoptosis of Human Natural Killer Cells Identifies a Novel Mechanism to Regulate the Innate Immune Response ME Ross, MA Caligiuri	Blood	1997
Interleukin-15 Triggers the Proliferation and Cytotoxicity of Granular Lymphocytes in Patients With Lymphoproliferative Disease of Granular Lymphocytes R Zambello, M Facco, L Trentin, R Sancetta, C Tassinari, A Perin, A Milani, G Pizzolo, F Rodeghiero, C Agostini, R Meazza, S Ferrini, G Semenzato	Blood	1997
The Role of Interleukin-10 (IL-10) in IL-15–Mediated T-Cell Responses D Körholz, U Banning, H Bönig, M Grewe, M Schneider, C Mauz-Körholz, A Klein-Vehne, J Krutmann, S Burdach	Blood	1997
Human natural killer cells produce abundant macrophage inflammatory protein-1 alpha in response to monocyte-derived cytokines EM Bluman, KJ Bartynski, BR Avalos, MA Caligiuri	Journal of Clinical Investigation	1996
Characterization of interleukin-15 (IL-15) and the IL-15 receptor complex MK Kennedy, LS Park	Journal of Clinical Immunology	1996
IL-15: A Pleiotropic Cytokine with Diverse Receptor/Signaling Pathways Whose Expression Is Controlled at Multiple Levels Y Tagaya, RN Bamford, AP DeFilippis, TA Waldmann	Immunity	1996
NK cell proliferation and inflammation HS Warren	Immunology and Cell Biology	1996
CD8+ Lymphocyte Responses to Antiretroviral Therapy of HIV Infection A Carr, S Emery, A Kelleher, M Law, DA Cooper	Journal of Acquired Immune Deficiency Syndromes and Human Retrovirology	1996
Differential effects of interleukin-12, interleukin-15, and interleukin-2 on human immunodeficiency virus type 1 replication in vitro M Bayard-McNeeley, H Doo, S He, A Hafner, WD Johnson, JL Ho	Clinical and diagnostic laboratory immunology	1996
The Instructive Role of Innate Immunity in the Acquired Immune Response DT Fearon, RM Locksley	Science	1996
Interleukin 12: Basic Biology and Potential Applications in Cancer Treatment MJ Robertson, J Ritz	The oncologist	1996

Advertisement