Go to
JCI Insight
Citations to this article
Peter A. Rice, Dennis L. Kasper
Published July 1, 1982
Citation Information: J Clin Invest. 1982;70(1):157-167. https://doi.org/10.1172/JCI110589.
Citation Information: J Clin Invest. 1982;70(1):157-167. https://doi.org/10.1172/JCI110589.
Abstract
Neisseria gonorrhoeae isolated from patients with disseminated infection (DGI) often resist complement (C′)-dependent killing by normal human serum (NHS) and less commonly by convalescent DGI serum. 7 of 10 NHS specimens completely inhibited killing of serum-resistant (serr) gonococci by convalescent or immune DGI serum. Immunoglobulin G (IgG) purified from NHS was shown to be the blocking agent. In addition, IgM (plus C′) purified from NHS was shown to be fivefold more effective (wt/wt) in killing serum-sensitive (sers) gonococci than equivalent amounts of IgM tested in the presence of IgG (whole serum). Although inhibition of NHS killing of sers gonococci required a 640% excess of IgG, only a 40% excess was required to block immune serum killing of serr gonococci. F(ab′)2 prepared from IgG also blocked killing of serr gonococci by immune serum indicating antigenic specificity of blocking IgG.
Authors
Peter A. Rice, Dennis L. Kasper
Total citations by year
Citation information
Citations to this article (59)
| Title and authors | Publication | Year |
|---|---|---|
|
Mechanisms of antibody-dependent enhancement of infectious disease.
Wells TJ, Esposito T, Henderson IR, Labzin LI |
Nature reviews. Immunology | 2024 |
|
Gonococcal PorB: a multifaceted modulator of host immune responses
Jones RA, Jerse AE, Tang CM |
Trends in Microbiology | 2024 |
|
Mechanisms of host manipulation by Neisseria gonorrhoeae
Walker E, van Niekerk S, Hanning K, Kelton W, Hicks J |
Frontiers in microbiology | 2023 |
|
Preclinical efficacy of a cell division protein candidate gonococcal vaccine identified by artificial intelligence
Gulati S, Mattsson AH, Schussek S, Zheng B, DeOliveira RB, Shaughnessy J, Lewis LA, Rice PA, Comstedt P, Ram S |
mBio | 2023 |
|
Antibody-Dependent Enhancement of Bacterial Disease: Prevalence, Mechanisms, and Treatment
VV Torres, CF Coggon, TJ Wells, AR Richardson |
Infection and immunity | 2021 |
|
Complement interactions with the pathogenic Neisseriae: clinical features, deficiency states, and evasion mechanisms
LA Lewis, S Ram |
FEBS Letters | 2020 |
|
Human Immune Responses and the Natural History of Neisseria gonorrhoeae Infection
A Lovett, JA Duncan |
Frontiers in immunology | 2019 |
|
Gonorrhea – an evolving disease of the new millennium
SA Hill, TL Masters, J Wachter |
Microbial Cell | 2016 |
|
Methods in Enzymology
JD Stone, AS Chervin, DH Aggen, DM Kranz |
Protein Engineering for Therapeutics Part B | 2012 |
|
Advances in Clinical Chemistry
M Mahler |
Advances in Clinical Chemistry Volume 54 | 2011 |
|
Resistance of Neisseria gonorrhoeae to neutrophils
MB Johnson, AK Criss |
Frontiers in microbiology | 2011 |
|
Gonococcal Infections
JE Embree |
Infectious Diseases of the Fetus and Newborn | 2011 |
|
Antibiotic and Chemotherapy
P Moss |
Antibiotic and Chemotherapy | 2010 |
|
An Evaluation of the Role of Properdin in Alternative Pathway Activation on Neisseria meningitidis and Neisseriagonorrhoeae
S Agarwal, VP Ferreira, C Cortes, MK Pangburn, PA Rice, S Ram |
Journal of immunology (Baltimore, Md. : 1950) | 2010 |
|
The role of complement in gonococcal infection of cervical epithelia
JL Edwards |
Vaccine | 2008 |
|
Mucosal Immunology
WR Brown |
Mucosal Immunology | 2005 |
|
The Molecular Mechanisms Used by Neisseria gonorrhoeae To Initiate Infection Differ between Men and Women
JL Edwards, MA Apicella |
Clinical microbiology reviews | 2004 |
|
Musculoskeletal Infections
M Shirtliff, J Leid, J Costerton |
Musculoskeletal Infections | 2003 |
|
Acute septic arthritis
ME Shirtliff, JT Mader |
Clinical microbiology reviews | 2002 |
|
High Affinity Mimotope of the Polysaccharide Capsule of Cryptococcus neoformans Identified from an Evolutionary Phage Peptide Library
DO Beenhouwer, RJ May, P Valadon, MD Scharff |
Journal of immunology (Baltimore, Md. : 1950) | 2002 |
|
Strategies for Mimicking Neisserial Saccharide Epitopes as Vaccines
S Gulati, J Ngampasutadol, R Yamasaki, DP McQuillen, PA Rice |
International Reviews of Immunology | 2001 |
|
Molecular Mimicry, Microbes, and Autoimmunity
MW Cunningham, RS Fujinami |
2000 | |
|
Binding of complement factor H to loop 5 of porin protein 1A: a molecular mechanism of serum resistance of nonsialylated Neisseria gonorrhoeae
S Ram, DP McQuillen, S Gulati, C Elkins, MK Pangburn, PA Rice |
Journal of Experimental Medicine | 1998 |
|
GONOCOCCAL ARTHRITIS
E Cucurull, LR Espinoza |
Rheumatic Disease Clinics of North America | 1998 |
|
Binding of Complement Factor H to Loop 5 of Porin Protein 1A: A Molecular Mechanism of Serum Resistance of Nonsialylated Neisseria gonorrhoeae
S Ram, DP McQuillen, S Gulati, C Elkins, MK Pangburn, PA Rice |
Journal of Experimental Medicine | 1998 |
|
Systemic gonococcal infection
JD Ross |
Genitourinary medicine | 1996 |
|
Neisserial porins inhibit human neutrophil actin polymerization, degranulation, opsonin receptor expression, and phagocytosis but prime the neutrophils to increase their oxidative burst
R Bjerknes, HK Guttormsen, CO Solberg, LM Wetzler |
Infection and immunity | 1995 |
|
Complement Activation and Sensitizing Antibodies in Lyme Borreliosis. A Microbial Adherence Immobilization Assay for Borrelia burgdorferi (MAIA-BB)
B Cacciapuoti, L Ciceroni, L Fontana, R Perricone |
Zentralblatt für Bakteriologie | 1993 |
|
The Complement System
A Agostoni, M Cicardi, M Gardinali, L Bergamaschini |
International journal of immunopathology and pharmacology | 1992 |
|
Emerging Targets in Antibacterial and Antifungal Chemotherapy
JA Sutcliffe, NH Georgopapadakou |
1992 | |
|
Infectious diseases associated with complement deficiencies
JE Figueroa, P Densen |
Clinical microbiology reviews | 1991 |
|
Binding of S protein by Neisseria gonorrhoeae and potential role in invasion
RJ Arko, CY Chen, WO Schalla, SK Sarafian, CL Taylor, JS Knapp, SA Morse |
Journal of clinical microbiology | 1991 |
|
Gonococcal Endocarditis: Twenty-Five Year Experience
JD Jackman, DB Glamann |
The American Journal of the Medical Sciences | 1991 |
|
Septic arthritis
RJ Williams, RL Smith, DJ Schurman |
Arthritis & Rheumatism | 1990 |
|
Lacto- and ganglio-series glycolipids are adhesion receptors for Neisseria gonorrhoeae
CD Deal, HC Krivan |
The Journal of biological chemistry | 1990 |
|
Interaction of complement with Neisseria meningitidis and Neisseria gonorrhoeae
P Densen |
Clinical microbiology reviews | 1989 |
|
Interactions of Neisseria gonorrhoeae with human neutrophils
RF Rest, WM Shafer |
Clinical microbiology reviews | 1989 |
|
Molecular basis for serum resistance in Neisseria gonorrhoeae
PA Rice |
Clinical microbiology reviews | 1989 |
|
Sexually Transmitted Infections: Current Epidemiological Perspective on World-Wide Infections with Aspects on Transmission, Molecular Biology, Epidemiological Control and Prevention
D Danielsson, E Lycke |
Scandinavian Journal of Infectious Diseases | 1989 |
|
The construction and characterization of Neisseria gonorrhoeae lacking protein III in its outer membrane
L M Wetzler, E C Gotschlich, M S Blake, J M Koomey |
Journal of Experimental Medicine | 1989 |
|
Characterization and specificity of antibodies to protein I of Neisseria gonorrhoeae produced by injection with various protein I-adjuvant preparations
LM Wetzler, MS Blake, EC Gotschlich |
Journal of Experimental Medicine | 1988 |
|
Gonococci and Meningococci
JT Poolman |
1988 | |
|
Specificity of antibodies against Neisseria gonorrhoeae that stimulate neutrophil chemotaxis. Role of antibodies directed against lipooligosaccharides
P Densen, S Gulati, PA Rice |
Journal of Clinical Investigation | 1987 |
|
Physical heterogeneity of neisserial lipooligosaccharides reflects oligosaccharides that differ in apparent molecular weight, chemical composition, and antigenic expression
JM Griffiss, JP O'Brien, R Yamasaki, GD Williams, PA Rice, H Schneider |
Infection and immunity | 1987 |
|
Mechanisms of stable serum resistance of Neisseria gonorrhoeae
PA Rice, MS Blake, KA Joiner |
Antonie van Leeuwenhoek | 1987 |
|
Immunoglobulin G antibodies directed against protein III block killing of serum-resistant Neisseria gonorrhoeae by immune serum
PA Rice, HE Vayo, MR Tam, MS Blake |
Journal of Experimental Medicine | 1986 |
|
Protection by serum antibodies in experimental nontypable Haemophilus influenzae otitis media
SJ Barenkamp |
Infection and immunity | 1986 |
|
Antigenic and physical diversity of Neisseria gonorrhoeae lipooligosaccharides
R Mandrell, H Schneider, M Apicella, W Zollinger, PA Rice, JM Griffiss |
Infection and immunity | 1986 |
|
Characterization of antigens from nontypable Haemophilus influenzae recognized by human bactericidal antibodies. Role of Haemophilus outer membrane proteins
HE Gnehm, SI Pelton, S Gulati, PA Rice |
Journal of Clinical Investigation | 1985 |
|
Mechanism of action of blocking immunoglobulin G for Neisseria gonorrhoeae
KA Joiner, R Scales, KA Warren, MM Frank, PA Rice |
Journal of Clinical Investigation | 1985 |
|
Antigenic heterogeneity of lipid A of Haemophilus influenzae
MA Apicella, KC Dudas, A Campagnari, P Rice, JM Mylotte, TF Murphy |
Infection and immunity | 1985 |
|
Antigenic heterogeneity of outer membrane proteins of nontypable Haemophilus influenzae is a basis for a serotyping system
TF Murphy, MA Apicella |
Infection and immunity | 1985 |
|
Gonococcal Infection: A Model of Molecular Pathogenesis
BE Britigan, MS Cohen, PF Sparling |
New England Journal of Medicine | 1985 |
|
The Pathogenesis of Bacterial Infections
GG Jackson, H Thomas |
1985 | |
|
Bacteria and Complement
M Loos |
1985 | |
|
Elaboration of a 3.6-kilodalton lipooligosaccharide, antibody against which is absent from human sera, is associated with serum resistance of Neisseria gonorrhoeae
H Schneider, JM Griffiss, RE Mandrell, GA Jarvis |
Infection and immunity | 1985 |
|
Generation and characterization of monoclonal antibodies to the phenolic glycolipid of Mycobacterium leprae
DB Young, SR Khanolkar, LL Barg, TM Buchanan |
Infection and immunity | 1984 |
|
Immunoglobulin A from bronchopulmonary secretions blocks bactericidal and opsonizing effects of antibody to nontypable Haemophilus influenzae
DM Musher, A Goree, RE Baughn, HH Birdsall |
Infection and immunity | 1984 |
|
The role of complement in host resistance to bacteria
EJ Brown, KA Joiner, MM Frank |
Springer Seminars in Immunopathology | 1983 |
Copyright © 2025 American Society for Clinical Investigation
ISSN: 0021-9738 (print), 1558-8238 (online)