Citations to this article

Deletion of the A gamma-globin gene in G gamma-delta beta-thalassemia.
S H Orkin, … , B P Alter, C Altay
S H Orkin, … , B P Alter, C Altay
Published September 1, 1979
Citation Information: J Clin Invest. 1979;64(3):866-869. https://doi.org/10.1172/JCI109535.
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Research Article

Deletion of the A gamma-globin gene in G gamma-delta beta-thalassemia.

Abstract

In an individual homozygous for G gamma-delta beta-thalassemia, a physical alteration in gamma-globin gene organization was detected by restriction enzyme mapping. The data indicated that the absence of A gamma-globin chains resulted from extension of the DNA deletion from the delta beta-globin gene region into the gamma-globin gene region rather than a functional disturbance of gamma-gene expression.

Authors

S H Orkin, B P Alter, C Altay

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Citations to this article in year 2007 (1)

Title and authors Publication Year
Thalassemia intermedia due to homozygosity for an Asian Indian (Aγδβ)° deletional inversion
A Nadkarni, R Surve, M Holay, A Dani, A Shrikhande, V Bharti, S Suryawanshi, R Colah⁎, K Ghosh 		Clinica Chimica Acta 2007

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