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The metabolism of low density lipoprotein in familial type II hyperlipoproteinemia

Terry Langer, … , Warren Strober, Robert I. Levy

Terry Langer, … , Warren Strober, Robert I. Levy

Published June 1, 1972
Citation Information: J Clin Invest. 1972;51(6):1528-1536. https://doi.org/10.1172/JCI106949.

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Citations to this article (499)

Title and authors	Publication	Year
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HDL-free cholesterol influx into macrophages and transfer to LDL correlate with HDL-free cholesterol content Yelamanchili D, Gillard BK, Gotto AM Jr, Achirica MC, Nasir K, Remaley AT, Rosales C, Pownall HJ	Journal of Lipid Research	2024
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Absorption and Distribution Kinetics of the 13C-Labeled Tomato Carotenoid Phytoene in Healthy Adults NE Moran, JA Novotny, MJ Cichon, KM Riedl, RB Rogers, EM Grainger, SJ Schwartz, JW Erdman, SK Clinton	The Journal of nutrition	2015
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The atherogenic Scarb1 null mouse model shows a high bone mass phenotype C Martineau, L Martin-Falstrault, L Brissette, R Moreau	American journal of physiology. Endocrinology and metabolism	2013
Detection of oxidized and glycated proteins in clinical samples using mass spectrometry — A user's perspective PJ Thornalley, N Rabbani	Biochimica et Biophysica Acta (BBA) - General Subjects	2013
Rat rotator cuff tendon-to-bone healing properties are adversely affected by hypercholesterolemia DP Beason, JJ Tucker, CS Lee, L Edelstein, JA Abboud, LJ Soslowsky	Journal of Shoulder and Elbow Surgery	2013
The Pathogenic Role of the Adaptive Immune Response to Modified LDL in Diabetes G Virella, MF Lopes-Virella	Frontiers in Endocrinology	2012
Methods in Enzymology JD Stone, AS Chervin, DH Aggen, DM Kranz	Protein Engineering for Therapeutics Part B	2012
Advances in Food and Nutrition Research N Siriwardhana, NS Kalupahana, N Moustaid-Moussa	Marine Medicinal Foods - Implications and Applications - Animals and Microbes	2012
Hypercholesterolemia increases supraspinatus tendon stiffness and elastic modulus across multiple species DP Beason, JE Hsu, SM Marshall, AL McDaniel, RE Temel, JA Abboud, LJ Soslowsky	Journal of Shoulder and Elbow Surgery	2012
Advances in Clinical Chemistry M Mahler	Advances in Clinical Chemistry Volume 54	2011
Understanding hypertriglyceridemia in women: clinical impact and management with prescription omega-3-acid ethyl esters TD Dayspring	International journal of women's health	2011
Dairy calcium intake modifies responsiveness of fat metabolism and blood lipids to a high-fat diet JK Lorenzen, A Astrup	British Journal of Nutrition	2011
Methylglyoxal modification of LDL: proatherogenicity without oxidation opens new paths to prevent cardiovascular disease PJ Thornalley, N Rabbani	Clinical Lipidology	2011
Methylglyoxal, glyoxalase 1 and the dicarbonyl proteome N Rabbani, PJ Thornalley	Amino Acids	2010
The genetic basis of familial hypercholesterolemia: inheritance, linkage, and mutations ID Castro-Orós, M Pocoví, F Civeira	The Application of Clinical Genetics	2010
Increased Glycation and Oxidative Damage to Apolipoprotein B100 of LDL Cholesterol in Patients With Type 2 Diabetes and Effect of Metformin N Rabbani, MV Chittari, CW Bodmer, D Zehnder, A Ceriello, PJ Thornalley		2010
Lipoproteins, cholesterol homeostasis and cardiac health TF Daniels, KM Killinger, JJ Michal, RW Wright, Z Jiang	International journal of biological sciences	2009
Influence of oxidized low-density lipoproteins (LDL) on the viability of osteoblastic cells MR Brodeur, L Brissette, L Falstrault, P Ouellet, R Moreau	Free radical biology & medicine	2008
HDL3reduces the association and modulates the metabolism of oxidized LDL by osteoblastic cells: A protection against cell death MR Brodeur, L Brissette, L Falstrault, R Moreau	Journal of Cellular Biochemistry	2008
Mechanisms of Disease: genetic causes of familial hypercholesterolemia AK Soutar, RP Naoumova	Nature Clinical Practice Cardiovascular Medicine	2007
Scavenger Receptor of Class B Expressed by Osteoblastic Cells Are Implicated in the Uptake of Cholesteryl Ester and Estradiol From LDL and HDL3 MR Brodeur, L Brissette, L Falstrault, V Luangrath, R Moreau	Journal of Bone and Mineral Research	2007
Studying apolipoprotein turnover with stable isotope tracers: correct analysis is by modeling enrichments R Ramakrishnan	Journal of lipid research	2006
Encyclopedia of Molecular Cell Biology and Molecular Medicine E Beutler	Encyclopedia of Molecular Cell Biology and Molecular Medicine	2006
Differential abilities of mouse liver parenchymal and nonparenchymal cells in HDL and LDL (native and oxidized) association and cholesterol efflux J Lapointe, TQ Truong, L Falstrault, L Brissette	Biochemistry and Cell Biology	2006
In vivo cholesteryl ester selective uptake of mildly and standardly oxidized LDL occurs by both parenchymal and nonparenchymal mouse hepatic cells but SR-BI is only responsible for standardly oxidized LDL selective uptake by nonparenchymal cells G Bourret, MR Brodeur, V Luangrath, J Lapointe, L Falstrault, L Brissette	The International Journal of Biochemistry & Cell Biology	2006
Opposite effect of caveolin-1 in the metabolism of high-density and low-density lipoproteins TQ Truong, D Aubin, P Bourgeois, L Falstrault, L Brissette	Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids	2006
Lipid Metabolism and Health S Navare, P Thompson	Lipid Metabolism and Health	2005
Apolipoproteins C-II and C-III inhibit selective uptake of low- and high-density lipoprotein cholesteryl esters in HepG2 cells K Huard, P Bourgeois, D Rhainds, L Falstrault, JS Cohn, L Brissette	The International Journal of Biochemistry & Cell Biology	2005
Low-density lipoprotein apolipoprotein B production differs between laboratory opossums exhibiting high and low lipemic responses to dietary cholesterol and fat RS Kushwaha, JF VandeBerg, R Rodriguez, J Chan, JL VandeBerg	Metabolism	2005
Hyperglycemia, Lipoprotein Glycation, and Vascular Disease A Veiraiah	Angiology	2005
Physiological importance of SR-BI in the in vivo metabolism of human HDL and LDL in male and female mice MR Brodeur, V Luangrath, G Bourret, L Falstrault, L Brissette	Journal of lipid research	2005
Localization and regulation of SR-BI in membrane rafts of HepG2 cells D Rhainds, P Bourgeois, G Bourret, K Huard, L Falstrault, L Brissette	Journal of cell science	2004
The Role of Human and Mouse Hepatic Scavenger Receptor Class B Type I (SR-BI) in the Selective Uptake of Low-Density Lipoprotein−Cholesteryl Esters D Rhainds, M Brodeur, J Lapointe, D Charpentier, L Falstrault, L Brissette	Biochemistry	2003
Primary hypercholesterolemia: genetic causes and treatment of five monogenic disorders CR Pullinger, JP Kane, MJ Malloy	Expert Review of Cardiovascular Therapy	2003
Structure-guided Protein Engineering Modulates Helix Bundle Exchangeable Apolipoprotein Properties RS Kiss, PM Weers, V Narayanaswami, J Cohen, CM Kay, RO Ryan	The Journal of biological chemistry	2003
A physiological pharmacokinetic model describing the disposition of lycopene in healthy men V Diwadkar-Navsariwala, JA Novotny, DM Gustin, JA Sosman, KA Rodvold, JA Crowell, M Stacewicz-Sapuntzakis, PE Bowen	Journal of lipid research	2003
Effect of taurine on cholesterol metabolism in hamsters: Up-regulation of low density lipoprotein (LDL) receptor by taurine S Murakami, Y Kondo, Y Toda, H Kitajima, K Kameo, M Sakono, N Fukuda	Life Sciences	2002
Elevated uptake of low density lipoprotein by drug resistant human leukemic cell lines L Tatidis, M Masquelier, S Vitols	Biochemical Pharmacology	2002
Dexamethasone stimulates very low density lipoprotein (VLDL) receptor gene expression in differentiating 3T3-L1 cells K Ensler, M Mohammadieh, A Bröijersén, B Angelin, M Gåfvels	Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids	2002
Effects of F2833 on cholesterol metabolism in the genetically hyperlipidemic rat K Ouguerram, C Lutton, A Delhon, T Magot	European Journal of Pharmacology	2001
Low and high density lipoprotein metabolism in primary cultures of hepatic cells from normal and apolipoprotein E knockout mice A Auger, TQ Truong, D Rhainds, J Lapointe, F Letarte, L Brissette	European Journal of Biochemistry	2001
Growth modulation of low density lipoprotein receptor sterol sensitivity in cultured human fibroblasts L Tatidis, S Vitols	Lipids	2001
Cholesterol catabolism in patients with acute myelogenous leukemia and hypocholesterolemia: suppressed levels of a circulating marker for bile acid synthesis L Tatidis, S Vitols, A Gruber, C Paul, M Axelson	Cancer Letters	2001
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The role of the LDL receptor in apolipoprotein B secretion J Twisk, DL Gillian-Daniel, A Tebon, L Wang, PH Barrett, AD Attie	Journal of Clinical Investigation	2000
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Low Density Lipoprotein as a Carrier of Cytostatics in Cancer Chemotherapy: Study of Stability of Drug-carrier Complexes in Blood M Masquelier, S Vitols, M Pålsson, U Mårs, B Larsson, C Peterson	Journal of Drug Targeting	2000
Structural Characterization of a Low Density Lipoprotein Receptor-active Apolipoprotein E Peptide, ApoE3-(126–183) V Raussens, MK Mah, CM Kay, BD Sykes, RO Ryan	The Journal of biological chemistry	2000
Analysis of low-density lipoprotein catabolism by primary cultures of hepatic cells from normal and low-density lipoprotein receptor knockout mice TQ Truong, A Auger, F Denizeau, L Brissette	Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids	2000
Uptake and fate of class B scavenger receptor ligands in HepG2 cells D Rhainds, L Falstrault, C Tremblay, L Brissette	European Journal of Biochemistry	1999
Evidence of circadian rhythm in low-density lipoprotein apoB catabolism and its impact on the estimation of kinetic parameters Werynski, Nahorski, Berglund, Ericsson, Angelin, Eriksson	European Journal of Clinical Investigation	1999
Selective uptake of cholesteryl ester from low density lipoprotein is involved in HepG2 cell cholesterol homeostasis MC Charest, D Rhainds, L Falstrault, T Matzouranis, L Brissette	European Journal of Biochemistry	1999
Mutation screening and genotype:phenotype correlation in familial hypercholesterolaemia CA Graham, E McClean, AJ Ward, ED Beattie, S Martin, M O’Kane, IS Young, DP Nicholls	Atherosclerosis	1999
Up-regulation of low density lipoprotein receptor by a novel isobenzofranone derivative, MD-700 S Murakami, I Nitanai, S Uchida, Y Kondo-Ohta, Y Asami, K Kondo, M Sato, A Kawashima, H Hara, K Tomisawa, HB Mei, CZ Xiang	Atherosclerosis	1999
Selective uptake of cholesteryl esters from various classes of lipoproteins by HepG2 cells L Brissette, MC Charest, L Falstrault, J Lafond, D Rhainds, C Tremblay, TQ Truong	Biochemistry and Cell Biology	1999
Human apolipoprotein E N-terminal domain displacement of apolipophorin III from insect low density lipophorin creates a receptor-competent hybrid lipoprotein CA Fisher, RS Kiss, GA Francis, P Gao, RO Ryan	Comparative Biochemistry and Physiology Part B: Biochemistry and Molecular Biology	1999
Influence of Etoposide on the Retention of Radiolabeled Low-Density Lipoprotein in the Arterial Wall M Krainer, M Rodrigues, C Zielinski, H Sinzinger	Archives of pathology & laboratory medicine	1999
Lipoprotein Receptors in Acute Myelogenous LeukemiaFailure to Detect Increased Low-Density Lipoprotein (LDL) Receptor Numbers in Cell Membranes despite Increased Cellular LDL Degradation M Rudling, M Gåfvels, P Parini, G Gahrton, B Angelin	The American Journal of Pathology	1998
Effect of reduced low-density lipoprotein receptor level on HepG2 cell cholesterol metabolism L Izem, E Rassart, L Kamate, L Falstrault, D Rhainds, L Brissette	Biochemical Journal	1998
Advances in Protein Chemistry CM Silva, J Isgaard, MO Thorner	Advances in Protein Chemistry	1998
What’s New in Cardiovascular Imaging? JH Reiber, EE Wall		1998
Simvastatin impairs mitogen-induced proliferation of malignant B-lymphocytes from humans—in vitro and in vivo studies S Vitols, B Angelin, G Juliusson	Lipids	1997
Rate of Low-Density Lipoprotein Cholesterol and Apolipoprotein B Changes on Initiation and Discontinuation of Atorvastatin Treatment RH Stern, RB Abel	The Journal of Clinical Pharmacology	1997
Plasma Kinetics of Cholesteryl Ester Transfer Protein in the Rabbit: Effects of Dietary Cholesterol R McPherson, P Lau, P Kussie, H Barrett, AR Tall	Arteriosclerosis, thrombosis, and vascular biology	1997
Detection of early atherosclerotic lesions in the carotid artery: Experimental and preliminary human data H Kritz, P Schmid, G Karanikas, M Rodrigues, H Sinzinger	International Journal of Angiology	1997
Decreased production of low density lipoprotein by atorvastatin after apheresis in homozygous familial hypercholesterolemia AD Marais, RP Naoumova, JC Firth, C Penny, CK Neuwirth, GR Thompson	Journal of lipid research	1997
Decreased feedback regulation of low density lipoprotein receptor activity by sterols in leukemic cells from patients with acute myelogenous leukemia L Tatidis, A Gruber, S Vitols	Journal of lipid research	1997
Selective uptake of cholesteryl esters of low-density lipoproteins is mediated by the lipoprotein-binding site in HepG2 cells and is followed by the hydrolysis of cholesteryl esters L Brissette, MC Charest, L Falstrault	Biochemical Journal	1996
The selective uptake of the cholesteryl esters of low density lipoproteins parallels the activity of protein kinase C L Brissette	Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism	1996
Metabolism of plasma lipoproteins in the genetically hypercholesterolemic rat (RICO) K Ouguerram, T Magot, C Lutton	Metabolism	1996
GENE THERAPY AND INHERITED DYSLIPIDEMIA TO MD	Endocrine Practice	1996
Drugs Affecting Lipid Metabolism AM Gotto, R Paoletti, LC Smith, AL Catapano, AS Jackson		1996
Binding affinity and particle size of LDL in subjects with moderate hypercholesterolemia: relationship with in vivo LDL metabolism K Yamane, S Kataoka, NA Le, M Paidi, WJ Howard, JS Hannah, BV Howard	Journal of lipid research	1996
Decreased clearance of low-density lipoprotein in uremic patients under dialysis treatment S Hörkkö, K Huttunen, YA Kesäniemi	Kidney International	1995
Uptake of high-density lipoprotein by Y-organs of the crab,Cancer antennarius. I. characterization in vitro and effects of stimulators and inhibitors BK Kang, E Spaziani	Archives of Insect Biochemistry and Physiology	1995
Uptake of high-density lipoprotein by Y-organs of the crab,cancer antennarius. II. formal characterization of receptor-mediation with isolated membranes BK Kang, E Spaziani	Archives of Insect Biochemistry and Physiology	1995
Uptake of high-density lipoprotein by Y-organs of the crabCancer antennarius: III. Evidence for adsorptive endocytosis and the absence of lysosomal processing BK Kang, E Spaziani	Journal of Experimental Zoology	1995
Radioactive Isotopes in Clinical Medicine and Research H Bergmann, H Sinzinger		1995
Development and application of a multicompartmental model to study very low density lipoprotein subfraction metabolism CJ Packard, A Gaw, T Demant, J Shepherd	Journal of lipid research	1995
Familial lipoprotein disorders and premature coronary artery disease EJ Schaefer, JJ Genest, JM Ordovas, DN Salem, PW Wilson	Atherosclerosis	1994
Decreased clearance of uraemic and mildly carbamylated low-density lipoprotein S Hörkkö, K Huttunen, K Kervinen, YA Kesäniemi	European Journal of Clinical Investigation	1994
Decreased clearance of low-density lipoprotein in patients with chronic renal failure S Hörkkö, K Huttunen, T Korhonen, YA Kesäniemi	Kidney International	1994
Extravascular circulation of lipoproteins: their role in reverse transport of cholesterol D Reichl	Atherosclerosis	1994
Effects of albumin on lipid synthesis, apo B-100 secretion, and LDL catabolism in HepG2 cells K Cianflone, H Vu, ZJ Zhang, AD Sniderman	Atherosclerosis	1994
In vitro oxidised HDL is recognised by the scavenger receptor of macrophages: implications for its protective role in vivo AE la Ville, R Sola, J Balanya, PR Turner, L Masana	Atherosclerosis	1994
Effects of ciprofibrate on LDL metabolism in man A Gaw, CJ Packard, MJ Caslake, BA Griffin, GM Lindsay, J Thomson, BD Vallance, D Wosornu, J Shepherd	Atherosclerosis	1994
Altered hepatic catabolism of low-density lipoprotein subjected to lipid peroxidation in vitro WL Stone, M Heimberg, RL Scott, I LeClair, HG Wilcox	Biochemical Journal	1994
Analysis of the selective uptake of the cholesteryl ester of human intermediate density lipoproteins by HepG2 cells L Brissette, L Falstrault	Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism	1994
ApoB metabolism in familial hypercholesterolemia. Inconsistencies with the LDL receptor paradigm WR Fisher, LA Zech, PW Stacpoole	Arteriosclerosis Thrombosis and Vascular Biology	1994
Radiolabeled Blood Elements J Martin-Comin, ML Thakur, C Piera, M Roca, F Lomeña		1994
Cholesterol kinetics in subjects with bile fistula. Positive relationship between size of the bile acid precursor pool and bile acid synthetic rate CC Schwartz, LA Zech, JM VandenBroek, PS Cooper	Journal of Clinical Investigation	1993
Low-density lipoprotein metabolism in rats treated with cyclosporine J López-Miranda, E Vilella, F Pérez-Jiménez, A Espino, JA Jiménez-Perepérez, L Masana, PR Turner	Metabolism	1993
The effects of hypercholesterolaemia, simvastatin and dietary fat on the low density lipoprotein receptor of unstimulated mononuclear cells PD Roach, J Hosking, PM Clifton, R Bais, B Kusenic, P Coyle, MB Wight, DW Thomas, PJ Nestel	Atherosclerosis	1993
Non-steady-state kinetics of low density lipoproteins in man: studies after plasma exchange in healthy subjects and patients with familial hypercholesterolaemia M Eriksson, L Berglund, J Gabrielsson, B Lantz, B Angelin	European Journal of Clinical Investigation	1993
Changes in Iipoprotein(a), LDL-cholesterol and apolipoprotein B in homozygous familial hypercholesterolaemic patients treated with dextran sulfate LDL-apheresis MA Lasunción, JL Teruel, JJ Alvarez, P Carrero, J Ortuño, D Gómez-Coronado	European Journal of Clinical Investigation	1993
The Gordon Wilson Lecture. Plasma cholesterol: atherogenesis and mortality WR Fisher	Transactions of the American Clinical and Climatological Association	1993
Lipoprotein Metabolism DR Illingworth	American Journal of Kidney Diseases	1993
Fenofibrate and LDL metabolic heterogeneity in hypercholesterolemia MJ Caslake, CJ Packard, A Gaw, E Murray, BA Griffin, BD Vallance, J Shepherd	Arteriosclerosis Thrombosis and Vascular Biology	1993
Plasma triglyceride and low density lipoprotein metabolism MJ Caslake, CJ Packard, JJ Series, B Yip, MM Dagen, J Shepherd	European Journal of Clinical Investigation	1992
Low density lipoprotein ligand-receptor interactions in normal healthy individuals characterized by their XbaI apolipoprotein B DNA polymorphism E Vilella, J Balanyà, L Masana, S Marsal, AE Ville, PR Turner	Atherosclerosis	1992
Familial hypercholesterolaemia and LDL receptor mutations AK Soutar	Journal of Internal Medicine	1992
Metabolism of plasma low density lipoproteins in familial combined hyperlipidaemia: effect of acipimox therapy S Ericsson, M Eriksson, L Berglund, B Angelin	Journal of Internal Medicine	1992
Importance of growth hormone for the induction of hepatic low density lipoprotein receptors M Rudling, G Norstedt, H Olivecrona, E Reihnér, JA Gustafsson, B Angelin	Proceedings of the National Academy of Sciences	1992
The effects of low density lipoprotein and high density lipoprotein on phosphoinositide hydrolysis in bovine aortic endothelial cells DE Myers, NH Fidge, H Stanton, RG Larkins	Atherosclerosis	1992
The visceral yolk sac — an important site of synthesis and secretion of apolipoprotein B containing lipoproteins in the feto-placental unit of the rat D Plonné, L Winkler, H Franke, R Dargel	Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism	1992
Effects of lovastatin therapy on very-low-density lipoprotein triglyceride metabolism in subjects with combined hyperlipidemia: Evidence for reduced assembly and secretion of triglyceride-rich lipoproteins Y Arad, R Ramakrishnan, HN Ginsberg	Metabolism	1992
Interaction of oxidized low density lipoproteins with both apo B,E and scavenger receptors. A model for its production in vitro E Vilella, J Joven, T Bargalló, PR Turner, L Masana	Clinica Chimica Acta	1992
Eicosapentaenoic acid inhibits cholesteryl ester accumulation in rat peritoneal macrophages by decreasing the number of specific binding sites of acetyl LDL I Saito, H Saito, Y Tamura, S Yoshida	Clinical Biochemistry	1992
Analysis of the binding and association of human intermediate density lipoproteins to HepG2 cells L Brissette, L Falstrault	Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism	1992
In vivo quantification of cholesterol content in human carotid arteries by quantitative Gamma-camera imaging after injection of autologous low density lipoproteins (LDL) I Virgolini, J O'Grady, G Lupattelli, F Rauscha, P Angelberger, S Ventura, H Sinzinger	International Journal of Radiation Applications and Instrumentation. Part B. Nuclear Medicine and Biology	1992
Comparison of methods for incorporating a radioiodinated residualizing cholesteryl ester analog into low density lipoprotein LE Deforge, MR Degalan, MK Ruyan, RS Newton, RE Counsell	International Journal of Radiation Applications and Instrumentation. Part B. Nuclear Medicine and Biology	1992
In vivo metabolism of apolipoprotein A-I in a patient with homozygous familial hypercholesterolemia JR Schaefer, DJ Rader, K Ikewaki, T Fairwell, LA Zech, MR Kindt, J Davignon, RE Gregg, HB Brewer	Arteriosclerosis Thrombosis and Vascular Biology	1992
Low and high density lipoprotein metabolism in atherothrombotic brain infarction R Alam, FM Yatsu, R Kasturi, G Bui	Stroke; a journal of cerebral circulation	1992
The effect of interferon on the metabolism of LDLs G Schectman, S Kaul, RA Mueller, EC Borden, AH Kissebah	Arteriosclerosis Thrombosis and Vascular Biology	1992
Characterization of chylomicron remnant clearance by retinyl palmitate label in normal humans F Berr	Journal of lipid research	1992
Influence of age on the metabolism of plasma low density lipoproteins in healthy males S Ericsson, M Eriksson, S Vitols, K Einarsson, L Berglund, B Angelin	Journal of Clinical Investigation	1991
Effect of chronic glucagon administration on lipoprotein composition in normally fed, fasted and cholesterol-fed rats C Guettet, N Rostaqui, D Mathe, B Lecuyer, N Navarro, B Jacotot	Lipids	1991
Low density lipoprotein receptor levels and the response to dietary and pharmacological intervention in polygenic hypercholesterolemia J Joven, E Vilella, L Masana, J Ansoleaga	Clinica Chimica Acta	1991
In vivo clearance of low-density lipoproteins and β-very-low-density lipoproteins in normal and hypercholesterolemic White Carneau pigeons JW Reagan, RW Clair	Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism	1991
In vivo effect of simvastatin on lipoprotein cholesteryl ester metabolism in normocholesterolemic volunteers T Magot, CL Malmendier, K Ouguerram, JF Lontie, C Lutton	Clinica Chimica Acta	1991
Comparison of different methods for LDL isolation and radioiodination on liver LDL receptor binding in vitro I Virgolini, P Angelberger, G Lupattelli, S Li, J Pidlich, E Molinari, H Sinzinger	International Journal of Radiation Applications and Instrumentation. Part B. Nuclear Medicine and Biology	1991
Hepatic metabolism of cholesterol in Crohn's disease JE Åkerlund, E Reihnér, B Angelin, M Rudling, S Ewerth, I Björkhem, K Einarsson	Gastroenterology	1991
Synthesis and evaluation of radioiodinated cholesteryl ethers as lipoprotein probes LE DeForge, MK Ruyan, SW Schwendner, RS Newton, RE Counsell	Bioconjugate Chemistry	1991
Quantitative studies of transfer in vivo of low density, Sf 12-60, and Sf 60-400 lipoproteins between plasma and arterial intima in humans M Shaikh, R Wootton, BG Nordestgaard, P Baskerville, JS Lumley, AE Ville, J Quiney, B Lewis	Arteriosclerosis Thrombosis and Vascular Biology	1991
Serum low density lipoprotein cholesterol level and cholesterol absorption efficiency are influenced by apolipoprotein B and E polymorphism and by the FH-Helsinki mutation of the low density lipoprotein receptor gene in familial hypercholesterolemia H Gylling, K Aalto-Setälä, K Kontula, TA Miettinen	Arteriosclerosis Thrombosis and Vascular Biology	1991
Metabolic pathways of apolipoprotein B in heterozygous familial hypercholesterolemia: studies with a [3H]leucine tracer WR Fisher, LA Zech, LL Kilgore, PW Stacpoole	Journal of lipid research	1991
Autologous low-density lipoprotein labelling allows characterization of human atherosclerotic lesions in vivo as to presence of foam cells and endothelial coverage I Virgolini, F Rauscha, G Lupattelli, P Angelberger, A Ventura, J O'Grady, H Sinzinger	European Journal of Nuclear Medicine	1991
Low density lipoprotein labelling characterizes experimentally induced atherosclerotic lesions in rabbits in vivo as to presence of foam cells and endothelial coverage I Virgolini, P Angelberger, J O'Grady, H Sinzinger	European Journal of Nuclear Medicine	1991
Impaired response of fibroblasts from patients with hyperapobetalipoproteinemia to acylation-stimulating protein KM Cianflone, MH Maslowska, AD Sniderman	Journal of Clinical Investigation	1990
Nuclear medicine and atherosclerosis H Sinzinger, I Virgolini	European Journal of Nuclear Medicine	1990
The Effect of Pravastatin in Relation to Low Density Lipoprotein Receptor Activity H Hayashi, C Naito, H Ito, M Kawamura, S Miyazaki	Current Medical Research and Opinion	1990
Effect of chronic renal failure on high-density lipoprotein kinetics MM Fuh, CM Lee, CY Jeng, DC Shen, SM Shieh, GM Reaven, YD Chen	Kidney International	1990
Uptake of low density lipoproteins by human leukemic cells in vivo: relation to plasma lipoprotein levels and possible relevance for selective chemotherapy S Vitols, B Angelin, S Ericsson, G Gahrton, G Juliusson, M Masquelier, C Paul, C Peterson, M Rudling, K Söderberg-Reid	Proceedings of the National Academy of Sciences	1990
Low density lipoprotein for delivery of a water-insoluble alkylating agent to malignant cells. In vitro and in vivo studies of a drug-lipoprotein complex S Vitols, K Söderberg-Reid, M Masquelier, B Sjöström, C Peterson	British Journal of Cancer	1990
Low density lipoprotein receptor-binding activity in human tissues: quantitative importance of hepatic receptors and evidence for regulation of their expression in vivo MJ Rudling, E Reihnér, K Einarsson, S Ewerth, B Angelin	Proceedings of the National Academy of Sciences	1990
Metabolic studies on the hypolipidaemic effect of guar gum PR Turner, J Tuomilehto, P Happonen, AE Ville, M Shaikh, B Lewis	Atherosclerosis	1990
Low-density lipoprotein metabolism in the nephrotic syndrome GL Warwick, MJ Caslake, JM Boulton-Jones, M Dagen, CJ Packard, J Shepherd	Metabolism	1990
Arteriosklerose A Maelicke	Nachrichten aus Chemie, Technik und Laboratorium	1990
Abnormalities of Lipoprotein Metabolism in Patients with the Nephrotic Syndrome J Joven, C Villabona, E Vilella, L Masana, R Albertí, M Vallés	New England Journal of Medicine	1990
Regulation of LTP-I secretion from human monocyte-derived macrophages by differentiation and cholesterol accumulation in vitro RA Faust, JH Tollefson, A Chait, JJ Albers	Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism	1990
Nonuniform radiolabeling of VLDL apolipoprotein B: implications for the analysis of studies of the kinetics of the metabolism of lipoproteins containing apolipoprotein B R Ramakrishnan, Y Arad, S Wong, HN Ginsberg	Journal of lipid research	1990
Computer program for iterative evaluation of fractional turnover rates by exponential regression: application to the turnover of VLDL-triglycerides in blood W Leonhardt, C Lüthke, F Leonhardt, U Julius	Computer Methods and Programs in Biomedicine	1990
Cholesterol Metabolism, Ldl, and the Ldl Receptor NB Myant	Cholesterol Metabolism, Ldl, and the Ldl Receptor	1990
99mTc-low density lipoprotein: Intracellularly trapped radiotracer for noninvasive imaging of low density lipoprotein metabolism in vivo S Vallabhajosula, SJ Goldsmith	Seminars in Nuclear Medicine	1990
Plasma membrane enrichment with cis-unsaturated fatty acids enhances LDL metabolism in U937 monocytes P Kuo, M Weinfeld, MA Rudd, P Amarante, J Loscalzo	Arteriosclerosis (Dallas, Tex.)	1990
Effect of dietary fat saturation and cholesterol on LDL composition and metabolism. In vivo studies of receptor and nonreceptor-mediated catabolism of LDL in cebus monkeys RJ Nicolosi, AF Stucchi, MC Kowala, LK Hennessy, DM Hegsted, EJ Schaefer	Arteriosclerosis (Dallas, Tex.)	1990
Lipoprotein(a), fibrin binding, and plasminogen activation J Loscalzo, M Weinfeld, GM Fless, AM Scanu	Arteriosclerosis (Dallas, Tex.)	1990
Regulation of apoB secretion from HepG2 cells: evidence for a critical role for cholesteryl ester synthesis in the response to a fatty acid challenge KM Cianflone, Z Yasruel, MA Rodriguez, D Vas, AD Sniderman	Journal of lipid research	1990
Lovastatin therapy reduces low density lipoprotein apoB levels in subjects with combined hyperlipidemia by reducing the production of apoB-containing lipoproteins: implications for the pathophysiology of apoB production Y Arad, R Ramakrishnan, HN Ginsberg	Journal of lipid research	1990
In vivo clearance of low density lipoprotein in pigeons occurs by a receptor-like mechanism that is not down-regulated by cholesterol feeding JW Reagan, LR Miller, RW Clair	The Journal of biological chemistry	1990
Tracer kinetic studies of the low density lipoprotein metabolism in the fetal rat: an example for estimation of flux rates in the nonsteady state D Plonné, B Schlag, L Winkler, R Dargel	Journal of lipid research	1990
Effects of estrogen on low density lipoprotein metabolism in males. Short-term and long-term studies during hormonal treatment of prostatic carcinoma M Eriksson, L Berglund, M Rudling, P Henriksson, B Angelin	Journal of Clinical Investigation	1989
Estimation of turnover of low density lipoproteins by simplified methods GL Vega, SM Grundy	Atherosclerosis	1989
Kinetik der Lipide und Lipoproteine mit Bestimmung der Recovery-Rate im Non Steady State nach Plasma-, Membranfiltrations- und Dextransulfatadsorptionsapherese bei Hypercholesterinämie - Kinetics of Lipids and Lipoproteins with Determination of Recovery Rates in non-steady state after Plasma-, Membranefiltration and Dextransulfate Adsorption Apheresis for Hypercholesterolemia W Schwartzkopff, H Gräfenhahn, A Nold, H Baeyer, A Bimmermann, J Schleicher	Biomedizinische Technik/Biomedical Engineering	1989
Kinetics of a heterogeneous population of particles in low density lipoprotein apolipoprotein B CL Malmendier, C Delcroix, JF Lontie	Atherosclerosis	1989
Human hepatic low-density lipoprotein receptors: associations of receptor activities in vitro with plasma lipid and apolipoprotein concentrations in vivo MN Nanjee, NE Miller	Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism	1989
Biodistribution of 1311-radiolabelled plasma low density lipoprotein in hyperlipidaemic Vervet monkeys S Wynchank, JE Fincham, JF Klopper, HJ Wasserman, MJ Weight	Atherosclerosis	1989
Ecdysteroid biosynthesis in the crustacean Y-organ and control by an eyestalk neuropeptide E Spaziani, RD Watson, MP Mattson, ZF Chen	Journal of Experimental Zoology	1989
Low density lipoprotein metabolism in rats with puromycin aminonucleoside-induced nephrotic syndrome J Joven, L Masana, C Villabona, E Vilella, T Bargalló, M Trias, M Figueras, PR Turner	Metabolism	1989
Effect of combined therapy with bezafibrate and cholestyramine on low-density lipoprotein metabolism in type IIa hypercholesterolemia JJ Series, MJ Caslake, C Kilday, A Cruickshank, T Demant, AR Lorimer, CJ Packard, J Shepherd	Metabolism	1989
Treatment of Diet-Resistant Polygenic Hypercholesterolaemic Patients with a New Nicotinate Derivative; In Vivo and In Vitro Low Density Lipoprotein Metabolic Studies L Masana, A Escobar, J Joven, R Sola, E Vilella, T Bargallo, PR Turner	The Journal of Clinical Pharmacology	1989
Reduction in plasma low-density lipoprotein cholesterol and urinary mevalonic acid by lovastatin in patients with heterozygous familial hypercholesterolemia AS Pappu, DR Illingworth, S Bacon	Metabolism	1989
Effect of dietary fat saturation and cholesterol on low density lipoprotein degradation by mononuclear cells of Cebus monkeys PC Kuo, MA Rudd, R Nicolosi, J Loscalzo	Arteriosclerosis (Dallas, Tex.)	1989
The use of low density lipoprotein receptor activity of lymphocytes to determine the prevalence of familial hypercholesterolaemia in a rural South African community K Steyn, MJ Weight, BR Dando, KJ Christopher, JE Rossouw	Journal of medical genetics	1989
Colestipol-induced changes in LDL composition and metabolism. II. Studies in humans SG Young, JL Witztum, TE Carew, RW Krauss, FT Lindgren	Journal of lipid research	1989
Chenodeoxycholic acid normalizes elevated lipoprotein secretion and catabolism in cerebrotendinous xanthomatosis GS Tint, H Ginsberg, G Salen, NA Le, S Shefer	Journal of lipid research	1989
Catabolic rate of low density lipoprotein is influenced by variation in the apolipoprotein B gene T Demant, RS Houlston, MJ Caslake, JJ Series, J Shepherd, CJ Packard, SE Humphries	Journal of Clinical Investigation	1988
Simvastatin and bezafibrate: Effects on serum lipoproteins and lecithin: Cholesterol acyltransferase activity in familial hypercholesterolaemia P Weisweiler	European Journal of Clinical Pharmacology	1988
Regulation of lipoprotein receptors on a rat hepatoma cell line T Tamai, W Patsch, G Schonfeld	Atherosclerosis	1988
Impaired low-density lipoprotein receptor activity in chronic B-lymphocytic leukaemia cells G Juliusson, S Vitols	European Journal of Haematology	1988
Modified plasma-derived lipoproteins in human atherosclerotic plaques M Shaikh, S Martini, JR Quiney, P Baskerville, AE Ville, NL Browse, R Duffield, PR Turner, B Lewis	Atherosclerosis	1988
Biochemical and pathological features of a modified strain of Watanabe heritable hyperlipidaemic rabbits PJ Gallagher, MN Nanjee, T Richards, WR Roche, NE Miller	Atherosclerosis	1988
Measurement of 125I-low density lipoprotein uptake in selected tissues of the squirrel monkey by quantitative autoradiography RG Tompkins, JJ Schnitzer, ML Yarmush, CK Colton, KA Smith	The American Journal of Pathology	1988
Low density lipoprotein kinetics in African Green monkeys showing variable cholesterolaemic responses to diets realistic for westernised people MJ Weight, AJ Benade, CJ Lombard, JE Fincham, M Marais, B Dando, JV Seier, D Kritchevsky	Atherosclerosis	1988
Influence of etofibrate on low density lipoprotein metabolism JJ Series, MJ Caslake, C Kilday, A Cruickshank, T Demant, CJ Packard, J Shepherd	Atherosclerosis	1988
Cyclic AMP decseases LDL catabolism and cholesterol synthesis in the human hepatoma cell line HepG2 C Maziere, JC Maziere, S Salmon, M Auclair, L Mora, M Moreau, J Polonovski	Biochemical and Biophysical Research Communications	1988
Sex difference in the saturable binding of low-density lipoprotein by liver membranes in ageing rats MN Nanjee, NE Miller	Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism	1988
Modelling of LDL-apheresis: System efficacy and rebound kinetics F Kochinke, H Baeyer, I Schwaner, H Gräfenhahn, A Nold, R Schwerdtfeger, W Schwartzkopff	Plasma Therapy and Transfusion Technology	1988
Bile acid metabolism in heterozygous familial hypercholesterolaemia: a study comparing affected and unaffected siblings of four kindreds B Angelin	European Journal of Clinical Investigation	1988
Menstrual cycle effect on plasma lipids DY Jones, JT Judd, PR Taylor, WS Campbell, PP Nair	Metabolism	1988
Changes in plasma lipids and lipoprotein cholesterol during a high altitude mountaineering expedition (4800 m) J Frzou, JP Richalet, T Coste, C Rathat	European Journal of Applied Physiology and Occupational Physiology	1988
Direct measurement of apolipoprotein B synthesis in human very low density lipoprotein using stable isotopes and mass spectrometry DR Cryer, T Matsushima, JB Marsh, M Yudkoff, PM Coates, JA Cortner	Journal of lipid research	1988
Guinea pig low density lipoproteins: structural and metabolic heterogeneity G Luc, MJ Chapman	Journal of lipid research	1988
Low density lipoproteins in atherosclerosis LL Rudel, JS Parks, FL Johnson, J Babiak	Journal of lipid research	1988
Metabolism of apoprotein B in selectively bred baboons with low and high levels of low density lipoproteins RS Kushwaha, GM Barnwell, KD Carey, HC McGill	Journal of lipid research	1988
In vivo regulation of human mononuclear leukocyte 3-hydroxy-3-methylglutaryl coenzyme A reductase. Decreased enzyme catalytic efficiency in familial hypercholesterolemia PW Stacpoole, DM Bridge, IM Alvarez, RB Goldberg, HJ Harwood	Journal of Clinical Investigation	1987
Suppression of apolipoprotein B production during treatment of cholesteryl ester storage disease with lovastatin. Implications for regulation of apolipoprotein B synthesis HN Ginsberg, NA Le, MP Short, R Ramakrishnan, RJ Desnick	Journal of Clinical Investigation	1987
Acetaldehyde modification of low density lipoprotein accelerates its catabolism in man YA Kesäniemi, K Kervinen, TA Miettinen	European Journal of Clinical Investigation	1987
Lipoprotein catabolism in rats with portacaval anastomosis on various diets EE Windler, GH Mum, H Greten	Atherosclerosis	1987
Enhanced degradation of low density lipoprotein in human monocyte-derived macrophages associated with an increase in its free fatty acid content H Hayashi, C Naito, H Ito, M Kawamura, S Miyazaki, M Kumai	Atherosclerosis	1987
2 Lipoproteins and atherosclerosis J Babiak, LL Rudel	Baillière's Clinical Endocrinology and Metabolism	1987
Role of the liver for the receptor-mediated catabolism of low-density lipoprotein in the 17α-ethinylestradiol-treated rat MJ Rudling	Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism	1987
In vivo metabolism of apolipoprotein S in humans. Comparison with apolipoprotein A-I metabolism CL Malmendier, JF Lontie, C Delcroix	Clinica Chimica Acta	1987
Effects of Serum from Oral Contraceptive Users on the Metabolism of Low Density Lipoprotein JD Bagdade, PV Subbaiah, JJ Albers	The American Journal of the Medical Sciences	1987
Hereditary hyperlipidemia in the rabbit due to overproduction of lipoproteins. I. Biochemical studies AL Ville, PR Turner, RM Pittilo, S Martini, CB Marenah, PM Rowles, G Morris, GA Thomson, N Woolf, B Lewis	Arteriosclerosis (Dallas, Tex.)	1987
Unsaturated fatty acids enhance low density lipoprotein uptake and degradation by peripheral blood mononuclear cells J Loscalzo, J Freedman, MA Rudd, I Barsky-Vasserman, DE Vaughan	Arteriosclerosis (Dallas, Tex.)	1987
Effects of MK‐733 on plasma lipid and lipoprotein levels in subjects with hypercholesterolaemia LA Simons, PJ Nestel, GD Calvert, CL lennings	The Medical Journal of Australia	1987
Biotinylation of low density lipoproteins via free amino groups without loss of receptor binding activity PD Roach, SP Noël	Journal of lipid research	1987
Effect of apoE on triglyceride emulsion interaction with hepatocyte and hepatoma G2 cells B Oswald, S Quarfordt	Journal of lipid research	1987
Detection of the low density lipoprotein (LDL) receptor on nitrocellulose paper with colloidal gold-LDL conjugates PD Roach, M Zollinger, SP Noël	Journal of lipid research	1987
Dexamethasone modulates lipoprotein metabolism in cultured human monocyte-derived macrophages. Stimulation of scavenger receptor activity LJ Hirsch, T Mazzone	Journal of Clinical Investigation	1986
Metabolic basis of hyperapobetalipoproteinemia. Turnover of apolipoprotein B in low density lipoprotein and its precursors and subfractions compared with normal and familial hypercholesterolemia B Teng, AD Sniderman, AK Soutar, GR Thompson	Journal of Clinical Investigation	1986
Ein Rezeptor-vermittelter Stoffwechselweg für die Cholesterin-Homöostase (Nobel-Vortrag) MS Brown, JL Goldstein	Angewandte Chemie	1986
Kinetic analysis of glycation as a tool for assessing the half-life of proteins E Schleicher, OH Wieland	Biochimica et Biophysica Acta (BBA) - General Subjects	1986
Evidence for kinetic heterogeneity among human low density lipoproteins DM Foster, A Chait, JJ Albers, RA Failor, C Harris, JD Brunzell	Metabolism	1986
Low density lipoprotein metabolism in familial combined hyperlipidemia and familial hypercholesterolemia: Kinetic analysis using an integrated model A Chait, DM Foster, JJ Albers, RA Failor, JD Brunzell	Metabolism	1986
Impaired hepatocyte binding, uptake and degradation of glucosylated low-density lipoproteins JE Triau, J Arbetter, EJ Schaefer	Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism	1986
Altered high density lipoprotein metabolism in patients with myeloproliferative disorders and hypocholesterolemia HN Ginsberg, NA Le, HS Gilbert	Metabolism	1986
Scavenger activity in monocyte-derived macrophages from atherothrombotic strokes FM Yatsu, R Alam, S Alam	Stroke; a journal of cerebral circulation	1986
Content of low density lipoprotein receptors in breast cancer tissue related to survival of patients MJ Rudling, L Stahle, CO Peterson, L Skoog	BMJ : British Medical Journal	1986
A receptor-mediated pathway for cholesterol homeostasis Brown, JL Goldstein	Science	1986
The effects of human low and high density lipoproteins on the binding of rat intermediate density lipoproteins to rat liver membranes L Brissette, SP Noël	The Journal of biological chemistry	1986
The effects of liposome-reconstituted apolipoproteins on the binding of rat intermediate density lipoproteins to rat liver membranes L Brissette, PD Roach, SP Noël	The Journal of biological chemistry	1986
Apolipoprotein A-IV. A determinant for binding and uptake of high density lipoproteins by rat hepatocytes E Dvorin, NL Gorder, DM Benson, AM Gotto	The Journal of biological chemistry	1986
Regulation of the production and catabolism of plasma low density lipoproteins in hypertriglyceridemic subjects. Effect of weight loss HN Ginsberg, NA Le, JC Gibson	Journal of Clinical Investigation	1985
Development of an integrated model for analysis of the kinetics of apolipoprotein B in plasma very low density lipoproteins, intermediate density lipoproteins, and low density lipoproteins WF Beltz, YA Kesäniemi, BV Howard, SM Grundy	Journal of Clinical Investigation	1985
Plasma apolipoprotein B metabolism in familial type III dysbetalipoproteinaemia PR Turner, C Cortese, R Wootton, C Marenah, NE Miller, B Lewis	European Journal of Clinical Investigation	1985
Suitable hollow fibre immunobioreactors for specific ex vivo removal of antibodies and antigens from plasma C Larue, V Gueraud, C Rivat	Clinical & Experimental Immunology	1985
Low Density Lipoprotein Receptor Activity in Human Leukemic Cells-Relation to Chromosome Aberrations R Lindquist, S Vitols, G Gahrton, Ä Öst, C Peterson	Acta Medica Scandinavica	1985
LDL receptors in bovine tissues assayed as the heparin-sensitive binding of 125I-labeled LDL in homogenates: relation between liver LDL receptors and serum cholesterol in the fetus and post term MJ Rudling, CO Peterson	Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism	1985
Limited nonenzymatic glucosylation of low-density lipoprotein does not alter its catabolism in tissue culture E Schleicher, B Olgemöller, J Schön, T Dürst, OH Wieland	Biochimica et Biophysica Acta (BBA) - Molecular Cell Research	1985
Enhancement of cholesteryl ester metabolism in cultured human monocyte-derived macrophages by verapamil FM Yatsu, R Alam, SS Alam	Biochimica et Biophysica Acta (BBA) - Molecular Cell Research	1985
Kinetic mechanisms determining variability in low density lipoprotein levels and rise with age SM Grundy, GL Vega, DW Bilheimer	Arteriosclerosis (Dallas, Tex.)	1985
Fenofibrate reduces low density lipoprotein catabolism in hypertriglyceridemic subjects J Shepherd, MJ Caslake, AR Lorimer, BD Vallance, CJ Packard	Arteriosclerosis (Dallas, Tex.)	1985
Influence of mevinolin on metabolism of low density lipoproteins in primary moderate hypercholesterolemia SM Grundy, GL Vega	Journal of lipid research	1985
Specific binding of high density lipoprotein (HDL3) is not related to sterol synthesis in rat intestinal mucosa A Kagami, NH Fidge, PJ Nestel	Journal of lipid research	1985
Low density lipoprotein metabolism in hypertriglyceridemic and normolipidemic patients with coronary heart disease GL Vega, WF Beltz, SM Grundy	Journal of lipid research	1985
Solubilization of the 17 alpha-ethinyl estradiol-stimulated low density lipoprotein receptor of male rat liver PD Roach, SP Noël	Journal of lipid research	1985
Hypocholesterolemic effects of mevinolin in patients with heterozygous familial hypercholesterolemia DR Illingworth, GJ Sexton	Journal of Clinical Investigation	1984
Zusammensetzung der Lipoproteinfraktionen VLDL, LDL und HDL bei Hyperlipämikern der Typen IIa, IIb, III, IV und V im Vergleich zu Stoffwechselgesunden V Hutt, HU Klör, JG Wechsler, H Ditschuneit	Clinical Chemistry and Laboratory Medicine	1984
Studies of lipoprotein metabolism in a patient with fish-eye disease PR Turner, LA Carlson, C Cortese, S Rao, CB Marenah, NE Miller, B Lewis	European Journal of Clinical Investigation	1984
WHY DOES PLASMA LOW DENSITY LIPOPROTEIN CONCENTRATION IN ADULTS INCREASE WITH AGE? NE Miller	The Lancet	1984
Regulation of low-density lipoprotein receptors in the human hepatoma cell line Hep G2 DR Illingworth, S Lindsey, FC Hagemenas	Experimental Cell Research	1984
Regulation of Low Density Lipoprotein Receptor Function in a Human Hepatoma Cell Line AM Leichtner, M Krieger, AL Schwartz	Hepatology	1984
Surface determinants of low density lipoprotein uptake by endothelial cells P Görög, JD Pearson	Atherosclerosis	1984
Increase of electrophoretic mobility and of content of soluble proteins of human plasma β-lipoproteins by incubation of plasma in vitro LA Carlson, J Regnstram	Atherosclerosis	1984
The hormonal stimulation of high-density lipoprotein binding, internalization and degradation by cultured rat adrenal cortical cells N Fidge, M Leonard-Kanevsky, P Nestel	Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism	1984
Low-density lipoproteins modified by lipid transfer protein have altered biological activity A Chait, S Eisenberg, A Steinmetz, JJ Albers, EL Bierman	Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism	1984
Clinical, biochemical, and genetic features in familial disorders of high density lipoprotein deficiency EJ Schaefer	Arteriosclerosis (Dallas, Tex.)	1984
Causal relationship between removal efficiency of low density lipoproteins and their composition following cholesterol feeding and cholestyramine therapy C Lacombe, G Corraze, M Nibbelink	Nutrition Research	1984
Characteristics of the binding of high-density lipoprotein3 by intact cells and membrane preparations of rat intestinal mucosa A Kagami, N Fidge, N Suzuki, P Nestel	Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism	1984
Turnover of low density lipoproteins during inhibition of cholesterol absorption by neomycin YA Kesäniemi, SM Grundy	Arteriosclerosis (Dallas, Tex.)	1984
Contribution of the receptor pathway to low density lipoprotein catabolism in humans. New methods for quantitation HR Slater, L McKinney, CJ Packard, J Shepherd	Arteriosclerosis (Dallas, Tex.)	1984
Inhibition of low density lipoprotein synthesis by dietary omega-3 fatty acids in humans DR Illingworth, WS Harris, WE Connor	Arteriosclerosis (Dallas, Tex.)	1984
Low density lipoprotein metabolism in familial combined hyperlipidemia. Mechanism of the multiple lipoprotein phenotypic expression AH Kissebah, S Alfarsi, DJ Evans	Arteriosclerosis (Dallas, Tex.)	1984
Protocol for efficient plasma sampling for low density lipoprotein turnover studies NA Le, HN Ginsberg, WV Brown	Journal of lipid research	1984
Plasma low density lipoprotein transport kinetics in noninsulin-dependent diabetes mellitus AH Kissebah, S Alfarsi, DJ Evans, PW Adams	Journal of Clinical Investigation	1983
Receptor-mediated catabolism of low density lipoprotein in man. Quantitation using glucosylated low density lipoprotein YA Kesaniemi, JL Witztum, UP Steinbrecher	Journal of Clinical Investigation	1983
Studies on the role of specific cell surface receptors in the removal of lipoprotein (a) in man F Krempler, GM Kostner, A Roscher, F Haslauer, K Bolzano, F Sandhofer	Journal of Clinical Investigation	1983
Cholesterol feeding increases low density lipoprotein synthesis CJ Packard, L McKinney, K Carr, J Shepherd	Journal of Clinical Investigation	1983
A novel method for generating region-specific monoclonal antibodies to modified proteins. Application to the identification of human glucosylated low density lipoproteins LK Curtiss, JL Witztum	Journal of Clinical Investigation	1983
Regulation and interaction of cholesterol, bile salt and lipoprotein synthesis in liver CA Barth	Klinische Wochenschrift	1983
The metabolic basis of familial hypercholesterolaemia NB Myant	Klinische Wochenschrift	1983
Modes of action of lipid-lowering diets in man: studies of apolipoprotein B kinetics in relation to fat consumption and dietary fatty acid composition C Cortese, Y Levy, ED Janus, PR Turner, SN Rao, NE Miller, B Lewis	European Journal of Clinical Investigation	1983
Atherosclerosis and apoproteins B and A-I PO Kwiterovich, AD Sniderman	Preventive Medicine	1983
Hydrocortisone decreases the internalization of low density lipoprotein in cultured human fibroblasts and arterial smooth muscle cells K Henze, A Chait, JJ Alber, EL Bierman	European Journal of Clinical Investigation	1983
Regulation of low density lipoprotein receptors by plasma lipoproteins from patients with abetalipoproteinemia DR Illingworth, NA Alam, EE Sundberg, FC Hagemenas, DL Layman	Proceedings of the National Academy of Sciences	1983
Effects of hypolipidemic therapy on cholesterol homeostasis in freshly isolated mononuclear cells from patients with heterozygous familial hypercholesterolemia EE Sundberg, DR Illingworth	Proceedings of the National Academy of Sciences	1983
Mevinolin and colestipol stimulate receptor-mediated clearance of low density lipoprotein from plasma in familial hypercholesterolemia heterozygotes DW Bilheimer, SM Grundy, MS Brown, JL Goldstein	Proceedings of the National Academy of Sciences	1983
Interaction of high-density lipoprotein with Trypanosoma brucei: Effect of membrane stabilizers MR Rifkin	Journal of Cellular Biochemistry	1983
A case of heterozygous familial hypercholesterolemia associated with hyperthyroidism: Effects of triiodothyronine on low-density lipoprotein receptor and cholesterol synthesis T Haba, Y Sakai, J Koizumi, S Miyamoto, H Mabuchi, R Takeda	Metabolism	1983
Comparison of binding and degradation of high density lipoprotein by intestinal mucosal cells, fibroblasts and adrenal cortical cells in culture NH Fidge, PJ Nestel, S Naoki	Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism	1983
The effect of human t and b lymphocytes on low-density lipoprotein catabolism by cultured fibroblasts K Hiramatsu, A Chait, EL Bierman	Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism	1983
Fate of intravenously administered high-density lipoprotein labeled with radioiodinated cholesteryl oleate in normal and hypolipidemic rats RE Counsell, N Korn, RC Pohland, SW Schwendner, RH Seevers	Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism	1983
Scavenger lipoprotein receptors are more effective in ligand internalization than low density lipoprotein receptors in human monocyte-macrophages GA Coetzee, A Chait	Biochemical and Biophysical Research Communications	1983
HDL3 degradation by proteases in isolated rat intestinal mucosal cells N Suzuki, N Fidge, P Nestel	Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism	1983
Metabolism of apoprotein B in cynomolgus monkey: evidence for independent production of low-density lipoprotein apoprotein B IJ Goldberg, NA Le, HN Ginsberg, JR Paterniti, WV Brown	American journal of physiology. Endocrinology and metabolism	1983
Increased low density lipoprotein production associated with obesity YA Kesaniemi, SM Grundy	Arteriosclerosis (Dallas, Tex.)	1983
Overproduction of low density lipoproteins associated with coronary heart disease YA Kesaniemi, SM Grundy	Arteriosclerosis (Dallas, Tex.)	1983
Increased catabolism of native and cyclohexanedione-modified low density lipoprotein in subjects with myeloproliferative diseases H Ginsberg, IJ Goldberg, P Wang-Iverson, E Gitler, NA Le, HS Gilbert, WV Brown	Arteriosclerosis (Dallas, Tex.)	1983
Lipoproteine und Lipoproteinrezeptoren und ihre Bedeutung f�r die Pathogenese der Arteriosklerose HA Dresel, G Schettler	Klinische Wochenschrift	1983
Effect of cholesterol feeding on the distribution of plasma lipoproteins and on the metabolism of apolipoprotein E in the rabbit RI Roth, JW Gaubatz, AM Gotto, JR Patsch	Journal of lipid research	1983
Interaction of serum lipoproteins with the intestine. Evidence for specific high density lipoprotein-binding sites on isolated rat intestinal mucosal cells N Suzuki, N Fidge, P Nestel, J Yin	Journal of lipid research	1983
Receptors for homologous plasma lipoproteins on a rat hepatoma cell line T Tamai, W Patsch, D Lock, G Schonfeld	Journal of lipid research	1983
The hypolipidemic action of probucol: a study of its effects on high and low density lipoproteins RF Atmeh, JM Stewart, DE Boag, CJ Packard, AR Lorimer, J Shepherd	Journal of lipid research	1983
Low density lipoprotein metabolism in the normal to moderately elevated range of plasma cholesterol: comparisons with familial hypercholesterolemia LA Simons, S Balasubramaniam, J Holland	Journal of lipid research	1983
Isopropanol precipitation method for the determination of apolipoprotein B specific activity and plasma concentrations during metabolic studies of very low density lipoprotein and low density lipoprotein apolipoprotein B G Egusa, DW Brady, SM Grundy, BV Howard	Journal of lipid research	1983
Significance of low density lipoprotein production in the regulations of plasma cholesterol level in man YA Kesaniemi, SM Grundy	Journal of Clinical Investigation	1982
Role of apolipoprotein E-containing lipoproteins in abetalipoproteinemia CB Blum, RJ Deckelbaum, LD Witte, AR Tall, J Cornicelli	Journal of Clinical Investigation	1982
Transfers and exchanges of esterified cholesterol between plasma lipoproteins PJ Barter, GJ Hopkins, GD Calvert	Biochemical Journal	1982
Impaired receptor-mediated catabolism of low density lipoprotein in the WHHL rabbit, an animal model of familial hypercholesterolemia DW Bilheimer, Y Watanabe, T Kita	Proceedings of the National Academy of Sciences	1982
Degradation by cultured fibroblasts and macrophages of unmodified and 1,2-cyclohexanedione-modified low-density lipoprotein from normal and homozygous familial hypercholesterolaemic subjects BL Knight, AK Soutar	Biochemical Journal	1982
Processing of acetylated human low-density lipoprotein by parenchymal and non-parenchymal liver cells. Involvement of calmodulin? TJ van Berkel, JF Nagelkerke, L Harkes, JK Kruijt	Biochemical Journal	1982
Effects of bezafibrate on receptor-mediated and receptor-independent low density lipoprotein catabolism in type II hyperlipoproteinaemic subjects JM Stewart, CJ Packard, AR Lorimer, DE Boag, J Shepherd	Atherosclerosis	1982
On the Pathogenesis of Acquired Hypo-β-Lipoproteinemia KS Bjerve, SA Evensen, S Stray-Pedersen, S Skrede	Acta Medica Scandinavica	1982
Evaluation of monoclonal antibodies to human plasma low density lipoproteins. A requirement for lipids to maintain antigenic structure JG Patton, MC Alley, SJ Mao	Journal of Immunological Methods	1982
Increased Uptake of Circulating Low-Density Lipoproteins and Fibrinogen by Arterial Walls After Removal of Sialic Acids from Their Endothelial Surface P Görög, GV Born	British Journal of Experimental Pathology	1982
National heart, lung, and blood institute type II coronary intervention study: Design, methods, and baseline characteristics JF Brensike, SF Kelsey, ER Passamani, MR Fisher, JM Richardson, IK Loh, NJ Stone, RF Aldrich, JW Battaglini, DJ Moriarty, MB Myrianthopoulos, KM Detre, SE Epstein, RI Levy	Controlled Clinical Trials	1982
Marked overproduction of low density lipoprotein apolipoprotein B in a subject with heterozygous familial hypercholesterolemia effect of portacaval shunting H Ginsberg, N Davidson, NA Le, J Gibson, EH Ahrens, WV Brown	Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism	1982
Low density lipoprotein receptor activity in freshly isolated human blood monocytes and lymphocytes A Chait, K Henze, T Mazzone, M Jensen, W Hammond	Metabolism	1982
Lipoprotein Kinetics and Modeling SM Grundy, GL Vega	Lipoprotein Kinetics and Modeling	1982
The LDL Receptor Defect in Familial Hypercholesterolemia: Implications for Pathogenesis and Therapy JL Goldstein, MS Brown	Medical Clinics of North America	1982
A secretory product of human monocyte-derived macrophages stimulates low density lipoprotein receptor activity in arterial smooth muscle cells and skin fibroblasts A Chait, T Mazzone	Arteriosclerosis (Dallas, Tex.)	1982
Autoregulation of the modified low density lipoprotein receptor in human monocyte-derived macrophages T Mazzone, A Chait	Arteriosclerosis (Dallas, Tex.)	1982
The hepatobiliary axis and lipoprotein metabolism: effects of bile acid sequestrants and ileal bypass surgery CJ Packard, J Shepherd	Journal of lipid research	1982
Reversible modification of human plasma low density lipoproteins toward triglyceride-rich precursors. A mechanism for losing excess cholesterol esters RJ Deckelbaum, S Eisenberg, Y Oschry, E Butbul, I Sharon, T Olivecrona	The Journal of biological chemistry	1982
Increased urinary excretion of glycosphingolipids in familial hypercholesterolemia S Chatterjee, CS Sekerke, PO Kwiterovich	Journal of lipid research	1982
Characterization of lipoprotein in a kindred with familial hypercholesterolemia W Patsch, R Ostlund, I Kuisk, R Levy, G Schonfeld	Journal of lipid research	1982
Metabolic heterogeneity of low density lipoprotein-apoB production in familial hypercholesterolemia: an analytical model solution of tracer data RP Eaton, RC Allen, DS Schade	Journal of lipid research	1982
Individual Variation in the Effects of Dietary Cholesterol on Plasma Lipoproteins and Cellular Cholesterol Homeostasis in Man STUDIES OF LOW DENSITY LIPOPROTEIN RECEPTOR ACTIVITY AND 3-HYDROXY-3-METHYLGLUTARYL COENZYME A REDUCTASE ACTIVITY IN BLOOD MON P Mistry, NE Miller, M Laker, WR Hazzard, B Lewis	Journal of Clinical Investigation	1981
Splanchnic metabolism of plasma apolipoprotein B: studies of artery-hepatic vein differences of mass and radiolabel in fasted human subjects PR Turner, NE Miller, C Cortese, W Hazzard, J Coltart, B Lewis	Journal of Clinical Investigation	1981
Effects of probucol on low density lipoprotein removal and high density lipoprotein synthesis PJ Nestel, T Billington	Atherosclerosis	1981
Selective removal of apolipoprotein B-containing serum lipoproteins from blood plasma W Stoffel, T Demant	Proceedings of the National Academy of Sciences	1981
Turnover and uptake by organs of radioactive serum high-density lipoprotein cholesteryl esters and phospholipids in the rat in vivo FM Hooft, TV Gent, AV Tol	Biochemical Journal	1981
Defects of receptor-mediated low density lipoprotein catabolism in homozygous familial hypercholesterolemia and hypothyroidism in vivo GR Thompson, AK Soutar, FA Spengel, A Jadhav, SJ Gavigan, NB Myant	Proceedings of the National Academy of Sciences	1981
Plasma lipid and apoprotein levels following plasmapheresis in a subject homozygous for familial hypercholesterolemia SI Barr, BA Kottke, AA Pineda, SJ Mao	Experientia	1981
FAMILIAL HYPERCHOLESTEROLAEMIA AND PRIMARY HYPOTHYROIDISM: COEXISTENCE OF BOTH DISORDERS IN A YOUNG WOMAN WITH SEVERE HYPERCHOLESTEROLAEMIA DR Illingworth, MR McCLUNG, WE Connor, P Alaupovic	Clinical Endocrinology	1981
SUPERIORITY OF PARTIAL ILEAL BYPASS OVER CHOLESTYRAMINE IN REDUCING CHOLESTEROL IN FAMILIAL HYPERCHOLESTEROLAEMIA FA Spengel, RG Duffield, A Jadhav, CB Wood, GR Thompson	The Lancet	1981
The effect of Ca2+ and trifluoperazine on the processing of human acetylated low density lipoprotein by non-parenchymal liver cells TJ Berkel, JF Nagelkerke, JK Kruijt	FEBS Letters	1981
The effects of hypothyroidism, age, and nutrition on LDL catabolism in the rat M Sykes, WM Cnoop-Koopmans, P Julien, A Angel	Metabolism	1981
Effect of a high carbohydrate diet on apoprotein-B catabolism in man HN Ginsberg, NA Le, J Melish, D Steinberg, WV Brown	Metabolism	1981
A physiologic role for the esterified cholesterol transfer protein: In vivo studies in rabbits and pigs YC Ha, GD Calvert, GH McIntosh, PJ Barter	Metabolism	1981
Integrated regulation of very low density lipoprotein triglyceride and apolipoprotein-B kinetics in man: Normolipemic subjects, familial hypertriglyceridemia and familial combined hyperlipidemia AH Kissebah, S Alfarsi, PW Adams	Metabolism	1981
Interconversions of diacylglycerol-transporting lipoproteins in the haemolymph of Locusta migratoria DJ der Horst, JM Doorn, AN Keijzer, AM Beenakkers	Insect Biochemistry	1981
The Biology of Cholesterol and Related Steroids NB Myant	The Biology of Cholesterol and Related Steroids	1981
Nutrition, Digestion, Metabolism J Hardcastle, PT Hardcastle, PA Sanford	Nutrition, Digestion, Metabolism	1981
The magnitude of metabolically induced changes in the density of human low-density lipoproteins P Weech, G Mills, H Meinertz, O Faergeman	Scandinavian Journal of Clinical & Laboratory Investigation	1981
Effect of changing dietary fat saturation on low-density lipoprotein metabolism in man JD Turner, NA Le, WV Brown	American journal of physiology. Endocrinology and metabolism	1981
Regulation of Plasma Cholesterol by Lipoprotein Receptors MS Brown, PT Kovanen, JL Goldstein	Science	1981
Lysosomal enzyme activities and low density lipoprotein receptors in circulating mononuclear cells: Effect of insulin therapy in diabetic patients K Henze, A Chait	Diabetologia	1981
Turnover of Lipoprotein (a) in Man F Krempler, GM Kostner, K Bolzano, F Sandhofer	Journal of Clinical Investigation	1980
Structure, Immunology, and Cell Reactivity of Low Density Lipoprotein from Umbilical Vein of a Newborn Type II Homozygote W Patsch, JL Witztum, R Ostlund, G Schonfeld	Journal of Clinical Investigation	1980
Serum profile of non-esterified fatty acids (NEFA) in patients with hyperlipoproteinemia under xantinol-nicotinate (XN) medication H Haacke, MR Parwaresch, C Mäder	Atherosclerosis	1980
Kinetic bases of the primar hperlipidaemias: studies of apolipoprotein B turnover in geneticall defined subjects ED Janus, AM Nicoll, PR Turner, P Magill, B Lewis	European Journal of Clinical Investigation	1980
Quantitative studies of ver low densit lipoprotein: conversion to low densit lipoprotein in normal controls and primar hperlipidaemic states and the role of direct secretion of low densit lipoprotein in heterozgous familial hpercholesterolaemia ED Janus, A Nicoll, R Wootton, PR Turner, PJ Magill, B Lewis	European Journal of Clinical Investigation	1980
Metabolism of endogenous plasma triglyceride in familial hypercholesterolaemia: studies of affected and unaffected siblings of two kindreds B Angelin	European Journal of Clinical Investigation	1980
Therapeutic effects of ML-236B in primary hypercholesterolemia A Yamamoto, H Sudo, A Endo	Atherosclerosis	1980
EVOLUTION OF THE LDL RECEPTOR CONCEPT?FROM CULTURED CELLS TO INTACT ANIMALS MS Brown, PT Kovanen, JL Goldstein	Annals of the New York Academy of Sciences	1980
Stability of plasma low density lipoprotein with abnormal glycolipid composition from patients with Fabry's disease JT Clarke, JM Stoltz, JB Garner	Atherosclerosis	1980
Very low density lipoprotein overproduction in genetic forms of hypertriglyceridaemia A Chait, JJ Albers, JD Brunzell	European Journal of Clinical Investigation	1980
St�rungen des Lipoprotein- und Fetts�urenstoffwechsels bei Schwerverletzten G Wolfram, J Eckart, N Z�llner	Klinische Wochenschrift	1980
Assessment of long-term plasma exchange for familial hypercholesterolaemia GR Thompson, NB Myant, D Kilpatrick, CM Oakley, MJ Raphael, RE Steiner	British heart journal	1980
Platelet-derived growth factor stimulates activity of low density lipoprotein receptors A Chait, R Ross, JJ Albers, EL Bierman	Proceedings of the National Academy of Sciences	1980
Effect of sialic acid removal on human low density lipoprotein catabolism in vivo CL Malmendier, C Delcroix, M Fontaine	Atherosclerosis	1980
Apolipoprotein B metabolism in normal, type IV, and type V hyperlipoproteinemic subjects CJ Packard, J Shepherd, S Joerns, AM Gotto, OD Taunton	Metabolism	1980
Cholestyramine Promotes Receptor-Mediated Low-Density-Lipoprotein Catabolism J Shepherd, CJ Packard, S Bicker, TD Lawrie, HG Morgan	New England Journal of Medicine	1980
A proposal linking clearance of circulating lipoproteins to tissue metabolic activity as a basis for understanding atherogenesis H Wolinsky	Circulation research	1980
Hydrolase activities in the rat aorta. IV. Relation between clearance rates of circulating 125I-labeled low-density lipoproteins and levels of tissue hydrolase activity H Wolinsky, D Katz, R Markle, J Mills, S Brem, S Wassertheil-Smoller	Circulation research	1980
Principles of Applied Clinical Chemistry S Natelson, EA Natelson		1980
Clinical Applications of Cardiovascular Drugs LS Dreifus, AN Brest		1980
Prediction of the parameters of whole body cholesterol metabolism in humans DS Goodman, FR Smith, AH Seplowitz, R Ramakrishnan, RB Dell	Journal of lipid research	1980
Effects of saturated and polyunsaturated fat diets on the chemical composition and metabolism of low density lipoproteins in man J Shepherd, CJ Packard, SM Grundy, D Yeshurun, AM Gotto, OD Taunton	Journal of lipid research	1980
St�rungen des Lipoprotein- und Fetts�urenstoffwechsels bei Schwerverletzten G Wolfram, J Eckart, N Zllner	Klinische Wochenschrift	1980
Metabolic Studies in an Unusual Case of Asymptomatic Familial Hypobetalipoproteinemia with Hypoalphalipoproteinemia and Fasting Chylomicronemia D Steinberg, SM Grundy, HY Mok, JD Turner, DB Weinstein, WV Brown, JJ Albers	Journal of Clinical Investigation	1979
Metabolic Studies in Familial Hypercholesterolemia EVIDENCE FOR A GENE-DOSAGE EFFECT IN VIVO DW Bilheimer, NJ Stone, SM Grundy	Journal of Clinical Investigation	1979
Lipolysis Produces Changes in the Immunoreactivity and Cell Reactivity of Very Low Density Lipoproteins G Schonfeld, W Patsch, B Pfleger, JL Witztum, SW Weidman	Journal of Clinical Investigation	1979
Low-density lipoprotein receptor activity in cultured human skin fibroblasts. Mechanism of insulin-induced stimulation A Chait, EL Bierman, JJ Albers	Journal of Clinical Investigation	1979
Rate of exchange of esterified cholesterol between human plasma low and high density lipoproteins PJ Barter, ME Jones	Atherosclerosis	1979
In vivo metabolism of esterified cholesterol and apoproteins in rabbit plasma low density lipoproteins YC Ha, GD Calvert, PJ Barter	Atherosclerosis	1979
The transport of control and hyperlipidemic low density lipoproteins from plasma to liver of rabbits OW Portman, M Alexander, R Kannan	Atherosclerosis	1979
LIPODYSTROPHY WITH HYPERLIPIDAEMIA: THE ROLE OF INSULIN IN VERY LOW DENSITY LIPOPROTEIN OVER-SYNTHESIS A Chait, E Janus, AS Mason, B Lewis	Clinical Endocrinology	1979
Binding of unmodified low-density lipoproteins to human fibroblasts. An investigation by immunoelectron microscopy BJ Vermeer, JF Koster, JJ Emeis, FC Reman, WC Bruijn	Biochimica et Biophysica Acta (BBA) - Biomembranes	1979
Pore models of sheep lung microvascular barrier using new data on protein tracers JE McNamee, NC Staub	Microvascular Research	1979
In vitro exchanges of esterified cholesterol between serum lipoprotein fractions: Studies of humans and rabbits PJ Barter, JI Lally	Metabolism	1979
Changes in lipoprotein composition during the menstrual cycle HJ Kim, RK Kalkhoff	Metabolism	1979
Reduction of plasma triglyceride concentration by acute stress in man A Chait, JD Brunzell, DG Johnson, JW Benson, P Werner, JP Palmer, JJ Albers, JW Ensinck, EL Bierman	Metabolism	1979
Low density lipoprotein metabolism in Type IV and Type V hyperlipoproteinemia JG Brook, H Torsvik, RS Lees, MA McCluskey, HA Feldman	Metabolism	1979
Drug management of hypercholesterolemia BL Martz	American Heart Journal	1979
A procedure for the preferential radioiodination of small amounts of protein in the presence of excess lipids RC Montelaro, DP Bolognesi	Analytical Biochemistry	1979
Further characterization of the oncornavirus inactivating factor in normal mouse serum RC Montelaro, PJ Fischinger, SB Larrick, NM Dunlop, JN Ihle, H Frank, W Schäfer, DP Bolognesi	Virology	1979
The metabolism of esterified cholesterol in rabbit plasma low density lipoproteins PJ Barter, JI Lally	Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism	1979
Lipoprotein (a) is not a metabolic product of other lipoproteins containing apolipoprotein B F Krempler, G Kostner, K Bolzano, F Sandhofer	Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism	1979
Very low density lipoprotein B-apoprotein kinetics in human subjects. relationships between pool size, flux, and removal rate PJ Nestel, MF Reardon, NH Fidge	Circulation research	1979
Plasma lipoproteins, lipid transport, and atherosclerosis: recent developments NE Miller	Journal of clinical pathology	1979
The cholesterol turnover, synthesis, and absorption in two sisters with familial hypercholesterolemia (type IIa) GA Carter, WE Connor, AK Bhattacharyya, DS Lin	Journal of lipid research	1979
Quantification of the hepatic contribution to the catabolism of high density lipoproteins in rats G Sigurdsson, SP Noel, RJ Havel	Journal of lipid research	1979
Receptor-mediated low density lipoprotein catabolism in man J Shepherd, S Bicker, AR Lorimer, CJ Packard	Journal of lipid research	1979
Low density lipoprotein metabolism and lipoprotein cholesterol content in southwestern American Indians MB Garnick, PH Bennett, T Langer	Journal of lipid research	1979
Biliary lipid secretion in hypercholesterolemia TN Tangedahl, AF Hofmann, BA Kottke	Journal of lipid research	1979
Genetics of the low density lipoprotein receptor. Diminished receptor activity in lymphocytes from heterozygotes with familial hypercholesterolemia DW Bilheimer, YK Ho, MS Brown, RG Anderson, JL Goldstein	Journal of Clinical Investigation	1978
Catabolism of Very Low Density Lipoprotein B Apoprotein in Man MF Reardon, NH Fidge, PJ Nestel	Journal of Clinical Investigation	1978
Low Density Lipoprotein A METABOLIC PATHWAY FOR RETURN OF CHOLESTEROL TO THE SPLANCHNIC BED A Sniderman, D Thomas, D Marpole, B Teng	Journal of Clinical Investigation	1978
Apoprotein a metabolism in tangier disease G Assmann, A Capurso, E Smootz, U Wellner	Atherosclerosis	1978
High density lipoprotein catabolism before and after partial hepatectomy AV Tol, TV Gent, FM Hooft, F Vlaspolder	Atherosclerosis	1978
Metabolism of apolipoproteins A-I and A-ll and its influence on the high density lipoprotein subfraction distribution in males and females J Shepherd, CJ Packard, JR Patsch, AM Gotto, OD Taunton	European Journal of Clinical Investigation	1978
Discrepancies in the catabolic pathways of rat and human low density lipoproteins as revealed by partial hepatectomy in the rat AV Tol, FM Hooft, TV Gent	Atherosclerosis	1978
Effect of intensive plasmapheresis on the plasma cholesterol concentration with familial hypercholesterolemia CS Apstein, DB Zilversmit, RS Lees, PK George	Atherosclerosis	1978
Lecithin: cholesterol acyl transfer rate and high density lipoproteins in plasma during dietary and cholestyramine treatment of type Ila hyperlipoproteinaemia L Wallentin	European Journal of Clinical Investigation	1978
Comparison of guinea-pig serum lipoproteins after iodination by two different methods PK Weech, F McTaggart, GL Mills	Biochemical Journal	1978
Studies on the metabolism of the lipoprotein Lp(a) in man F Krempler, G Kostner, K Bolzano, F Sandhofer	Atherosclerosis	1978
Effects of dietary saturated and polyunsaturated fat on the metabolism of apolipoproteins A-I and B J Shepherd, CJ Packard, AM Gotto, OD Taunton	Clinica Chimica Acta	1978
Impaired very low density lipoprotein and triglyceride removal in broad beta disease: Comparison with endogenous hypertriglyceridemia A Chait, WR Hazzard, JJ Albers, RP Kushwaha, JD Brunzell	Metabolism	1978
Importance of apolipoproteins in lipid metabolism BE Cham	Chemico-Biological Interactions	1978
Removal of cholesterol from fibroblasts and smooth muscle cells in culture in the presence and absence of cholesterol esterification in the medium O Stein, R Goren, Y Stein	Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism	1978
Similar behaviour of lecithin:cholesterol acyltrans- ferase and pseudocholinesterase in liver disease and hyperlipoproteinemia M Cucuianu, A Opincaru, D Tapalag<A	Clinica Chimica Acta	1978
Regulatory role of insulin in the degradation of low density lipoprotein by cultured human skin fibroblasts A Chait, EL Bierman, JJ Albers	Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism	1978
Iodine labeled human and rat low-density and high-density lipoprotein degradation by human liver and parenchymal and non-parenchymal cells from rat liver TJ van Berkel, A Tol, JF Koster	Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism	1978
Lecithin: Cholesterol Acyl Transfer Rate in Plasma and its Relations to Lipoprotein Concentrations and to Kinetics of Bile Acids and Triglycerides in Hyperlipoproteinemic Subjects L Wallentin, B Angelin, K Einarsson, B Leijd	Scandinavian Journal of Clinical & Laboratory Investigation	1978
Clinical Use of Cholestyramine Resin in Diarrheas of Various Etiology GG Stebbins, BC Carlstedt, NG Popovich		1978
The Lipoprotein Molecule H Peeters		1978
Metabolsim of apoB and apoC lipoproteins in man: kinetic studies in normal and hyperlipoproteininemic subjects M Berman, M Hall, RI Levy, S Eisenberg, DW Bilheimer, RD Phair, RH Goebel	Journal of lipid research	1978
Lipoprotein apoprotein metabolism EJ Schaefer, S Eisenberg, RI Levy	Journal of lipid research	1978
Bile acid kinetics in relation to endogenous tryglyceride metabolism in various types of hyperlipoproteinemia B Angelin, K Einarsson, K Hellström, B Leijd	Journal of lipid research	1978
Endogenously labeled low density lipoprotein triglyceride and apoprotein B kinetics C Malmendier, M Berman	Journal of lipid research	1978
Origin and transport of the A-I and arginine-rich apolipoproteins in mesenteric lymph of rats K Imaizumi, RJ Havel, M Fainaru, JL Vigne	Journal of lipid research	1978
Direct measurement of apoprotein B specific activity in 125I-labeled lipoproteins NA Le, JS Melish, BC Roach, HN Ginsberg, WV Brown	Journal of lipid research	1978
Catabolism of the apoprotein of low density lipoproteins by the isolated perfused rat liver G Sigurdsson, SP Noel, RJ Havel	Journal of lipid research	1978
High Density Lipoprotein Metabolism in Man CB Blum, RI Levy, S Eisenberg, MH 3rd, RH Goebel, M Berman	Journal of Clinical Investigation	1977
The distribution of labeled low-density lipoproteins across the rabbit thoracic aorta in vivo RL Bratzler, GM Chisolm, CK Colton, KA Smith, RS Lees	Atherosclerosis	1977
Intravenous fat tolerance Correlation with very low density lipoprotein apoprotein b kinetics in man A Nicoll, G Sigurdsson, A Marsh, B Lewis	Atherosclerosis	1977
Defects in enzyme regulation: A new approach to metabolic disorders DJ Galton, DJ Betteridge	Molecular Aspects of Medicine	1977
Hypertriglyceridemia in the diabetic rat Defective removal of serum very low density lipoproteins AV Tol	Atherosclerosis	1977
Metabolism of Very Low Density Lipoprotein of Sf 100-400 in Type V Hyperlipoproteinaemia FC Ballantyne, D Ballantyne, AG Olsson, S Rössner, LA Carlson	Acta Medica Scandinavica	1977
INFLUENCE OF LIPID CONCENTRATIONS AND AGE ON TRANSFER OF PLASMA LIPOPROTEIN INTO HUMAN ARTERIAL INTIMA CE Niehaus, R Wootton, J Lewis, A Nicoll, B Williams, DJ Coltart, B Lewis	The Lancet	1977
Changes in metabolic properties of rabbit very low density lipoproteins by dietary cholesterol, and saturated and polyunsaturated fat E Stange, M Alavi, J Papenberg	Atherosclerosis	1977
Simultaneous measurement of apolipoprotein B turnover in very-low- and low-density lipoproteins in familial hypercholesterolaemia AK Soutar, NB Myant, GR Thompson	Atherosclerosis	1977
The regulation of sterol biosynthesis in leucocytes of subjects with familial hypercholesterolaemia MJ Higgins, DJ Galton	European Journal of Clinical Investigation	1977
Serum Cholesterol and Triglycerides in Children with Anaemia M Seip, S Skrede	Scandinavian Journal of Haematology	1977
Lipoprotein composition in hypothyroidism ML Wahlqvist, NH Fidge, F Lomas	Clinica Chimica Acta	1977
Turnover of apolipoprotein-B in two subjects with familial hypobetalipoproteinemia G Sigurdsson, A Nicoll, B Lewis	Metabolism	1977
Familial hypercholesterolemia: Diagnosis, metabolic defect and management RL Jackson, LC Smith, OD Taunton, AM Gotto	Life Sciences	1977
Atherosclerosis: The low-density lipoprotein receptor hypothesis JL Goldstein, MS Brown	Metabolism	1977
The in vitro interaction of human apolipoprotein A-I and high density lipoproteins J Shepherd, AM Gotto, OD Taunton, MJ Caslake, E Farish	Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism	1977
The turnover of human plasma very low density lipoprotein protein SH Quarfordt	Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism	1977
Needed: New Therapy for Hypercholesterolemia DW Bilheimer	New England Journal of Medicine	1977
Lipid Metabolism in Mammals F Snyder		1977
Bile Acid Metabolism in Hyperlipoproteinaemia K Hellström, K Einarsson		1977
Binding, internalization, and degradation of high density lipoprotein by cultured normal human fibroblasts NE Miller, DB Weinstein, D Steinberg	Journal of lipid research	1977
A comparative study of surface binding of human low density and high density lipoproteins to human fibroblasts: regulation by sterols and susceptibility to proteolytic digestion T Koschinsky, TE Carew, D Steinberg	Journal of lipid research	1977
Parameters of the three-pool model of the turnover of plasma cholesterol in normal and hyperlipidemic humans FR Smith, RB Dell, RP Noble, DS Goodman	Journal of Clinical Investigation	1976
Effects of Intravenous Phospholipid on Low Density Lipoprotein Turnover in Man GR Thompson, A Jadhav, M Nava, AM Gotto	European Journal of Clinical Investigation	1976
Low density lipoprotein turnover in familial hypercholesterolaemia after plasma exchange GR Thompson, NB Myant	Atherosclerosis	1976
Relationships between plasma lipoprotein cholesterol concentrations and the pool size and metabolism of cholesterol in man NE Miller, PJ Nestel, P Clifton-Bligh	Atherosclerosis	1976
Treatment of hypercholesterolemia with Secholex A long-term clinical trial and comparison with cholestyramine EA Nikkila, TA Miettinen, Å Lanner	Atherosclerosis	1976
Metabolism of Very Low Density Lipoproteins in Hyperlipidaemia: Studies of Apolipoprotein B Kinetics in Man G Sigurdsson, A Nicoll, B Lewis	European Journal of Clinical Investigation	1976
The Metabolism of Low Density Lipoprotein in Endogenous Hypertriglyceridaemia G Sigurdsson, A Niooll, B Lewis	European Journal of Clinical Investigation	1976
Very low density lipoproteins in normal and cholesterol-fed rabbits: lipid and protein composition and metabolism JL Rodriguez, GC Ghiselli, D Torreggiani, CR Sirtori	Atherosclerosis	1976
Radioimmunoassay for human plasma apolipoprotein B DK Bedford, J Shepherd, HG Morgan	Clinica Chimica Acta	1976
Radioiodination of human low density lipoprotein: A comparison of four methods J Shepherd, DK Bedford, HG Morgan	Clinica Chimica Acta	1976
Low density lipoprotein metabolism in a family of familial hypercholesterolemic patients CJ Packard, JL Third, J Shepherd, AR Lorimer, HG Morgan, TD Lawrie	Metabolism	1976
Drug treatment of hyperlipidemia D Yeshurun, AM Gotto	The American Journal of Medicine	1976
The effects of dietary fat and cholesterol on the metabolism of plasma low density lipoprotein apoproteins in squirrel monkeys OW Portman, M Alexander, N Tanaka, P Soltys	Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism	1976
Uptake and degradation of low density lipoprotein by swine arterial smooth muscle cells with inhibition of cholesterol biosynthesis DB Weinstein, TE Carew, D Steinberg	Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism	1976
Low Density Lipoproteins CE Day, RS Levy		1976
Fettstoffwechsel G Assmann, J Augustin, E Baraona, HU Benz, W Brech, WV Brown, RJ Desnick, WR Fallat, S Ford, D Fredrickson, CJ Glueck, H Greten, K Harzer, P Herbert, GM Kostner, W Krivit, RI Levy, CS Lieber, M Liersch, G Middelhoff, GL Mills, NB Myant, RF ODea, J Papenberg, H Pilz, HM Rauen, S Sailer, G Schettler, G Schlierf, H Schriewer, D Seidel, J Slack, E Stange, O Stein, Y Stein, D Steinberg, A Weizel, H Wieland		1976
Rat high density lipoprotein subfraction (HDL3) uptake and catabolism by isolated rat liver parenchymal cells T Nakai, PS Otto, DL Kennedy, TF Whayne	The Journal of biological chemistry	1976
Metabolism of apoprotein B of plasma very low density lipoproteins in the rat O Faergeman, T Sata, JP Kane, RJ Havel	Journal of Clinical Investigation	1975
Reduction in cholesterol and low density lipoprotein synthesis after portacaval shunt surgery in a patient with homozygous familial hypercholesterolemia DW Bilheimer, JL Goldstein, SM Grundy, MS Brown	Journal of Clinical Investigation	1975
Conversion of very low density lipoprotein to low density lipoprotein. A metabolic study of apolipoprotein B kinetics in human subjects G Sigurdsson, A Nicoll, B Lewis	Journal of Clinical Investigation	1975
The plasma and tissue turnover and distribution of two radio-iodine-labelled pig plasma low density lipoproteins GD Calvert, PJ Scott, DN Sharpe	Atherosclerosis	1975
Radioimmunoassay of human plasma apolipoproteins GJ Bautovich, LA Simons, PF Williams, JR Turtle	Atherosclerosis	1975
PLASMA EXCHANGE IN THE MANAGEMENT OF HOMOZYGOUS FAMILIAL HYPERCHOLESTEROLÆMIA GR Thompson, R Lowenthal, NB Myant	The Lancet	1975
Effects of diet and type IIa hyperlipoproteinemia upon structure of triacylglycerols and phosphatidyl cholines from human plasma lipoproteins DT Gordon, RE Pitas, RG Jensen	Lipids	1975
Lecithin: Cholesterol acyltransferase activity in hypercholesterolemic subjects and in hypercholesterolemic subjects treated with clofibrate A D'Alessandro, A Zucconi, F Bellini, L Boncinelli, R Chiostri	Lipids	1975
Effect of diet on fatty acids in the lipoprotein cholesteryl esters of type IIa and normal individuals RS Newton, RE Pitas, RG Jensen	Lipids	1975
Lipidkonstellation in der Betalipoproteinfraktion der primären Typ II-Hyperlipoproteinämie H Haacke, MR Parwaresch, C Mäder	Klinische Wochenschrift	1975
The metabolism of the apoprotein of plasma low density lipoprotein in familial hype rbetalipoproteinaemia in the homozygous form LA Simons, D Reichl, NB Myant, M Mancini	Atherosclerosis	1975
Use of mutant fibroblasts in the analysis of the regulation of cholesterol metabolism in human cells MS Brown, PG Brannan, HA Bohmfalk, GY Brunschede, SE Dana, J Helgeson, JL Goldstein	Journal of Cellular Physiology	1975
75Se-selenomethionine-labeled lipoproteins in hyperlipidemic and normolipidemic humans HB Stähelin	Metabolism	1975
Serum pseudocholinesterase and ceruloplasmin in various types of hyperlipoproteinemia M Cucuianu, TA Popescu, A Opincaru, S Hǎrǎgus	Clinica Chimica Acta	1975
Human plasma triglyceride labeling after high sucrose feeding. II. Study on triglyceride kinetics and postheparin lipolytic activity CH Wu, WW Shreeve	Metabolism	1975
Coronary insufficiency in children D Bialostozky, M Luengo, C Magos, E Zorrilla	The American Journal of Cardiology	1975
Familial hypercholesterolemia JL Goldstein, MS Brown	The American Journal of Medicine	1975
The effects of hyperlipidemia on lbpoprotein metabolism in squirrel monkeys and rabbits OW Portman, DR Illingworth, M Alexander	Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism	1975
Homozygous Familial Hypercholesterolemia: A Possible Biochemical Explanation of Clinical Heterogeneity JL Breslow, DR Spaulding, SE Lux, RI Levy, RS Lees	New England Journal of Medicine	1975
Lipoprotein receptors and the genetic control of cholesterol metabolism in cultured human cells MS Brown, JL Goldstein	Die Naturwissenschaften	1975
Hypolipidemic Agents D Kritchevsky		1975
In vitro labeling of β-apolipoprotein with 3H or 14C and preliminary application to turnover studies VK Murthy, TC Monchesky, G Steiner	Journal of lipid research	1975
Turnover and tissue distribution of 125-I-labeled low density lipoprotein in swine and dogs AD Sniderman, TE Carew, D Steinberg	Journal of lipid research	1975
Abnormal induction of 3-hydroxy-3-methylglutaryl coenzyme A reductase in leukocytes from subjects with heterozygous familial hypercholesterolemia AM Fogelman, J Edmond, J Seager, G Popják	The Journal of biological chemistry	1975
Bile Acid Kinetics in Relation to Sex, Serum Lipids, Body Weights, and Gallbladder Disease in Patients with Various Types of Hyperlipoproteinemia K Einarsson, K Hellström, M Kallner	Journal of Clinical Investigation	1974
The Effect of Cholestyramine on the Elimination of Cholesterol as Bile Acids in Patients with Hyperlipoproteinaemia Type II and IV K Einarsson, K Hellstrom, M Kallner	European Journal of Clinical Investigation	1974
Serum cholesterol esterification in species resistant and susceptible to atherosclerosis AG Lacko, HL Rutenberg, LA Soloff	Atherosclerosis	1974
Effect of al-chlorophenoxyisobutyrate (alufibrate) on pyruvate metabolism and on the fate of very low density lipoprotein lipids in hyperlipidemic patients HB Stähelin, JT Locher, R Maier	Clinica Chimica Acta	1974
A review of methods and metabolic studies associated with the radioiodination of lipoproteins N Fidge	Clinica Chimica Acta	1974
A physiological method for labelling plasma lipoproteins with radioactive cholesterol HS Sodhi, BJ Kudchodkar	Clinica Chimica Acta	1974
Studies on the radioiodination of very low density lipoprotein obtained from different mammalian species NH Fidge, P Poulis	Clinica Chimica Acta	1974
Untersuchungen zum Stoffwechsel menschlicher Chylomikronen H Greten	Klinische Wochenschrift	1974
Expression of the Familial Hypercholesterolemia Gene in Heterozygotes: Mechanism for a Dominant Disorder in Man MS Brown, JL Goldstein	Science	1974
Influx of cholesterol into plasma in rabbits with fasting hyperbetalipoproteinemia HC Klauda, DB Zilversmit	Journal of lipid research	1974
Production of plasma esterified cholesterol in lean, normotriglyceridemic humans PJ Barter	Journal of lipid research	1974
CORRELATING METABOLISM OF PLASMA AND TISSUE CHOLESTEROL WITH THAT OF PLASMA-LIPOPROTEINS HS Sodhi, BJ Kudchodkar	The Lancet	1973
LIPOPROTEINS IN RELATION TO SKIN DISEASE FD Dean	British Journal of Dermatology	1973
Classification of lipoproteins and lipoprotein disorders B Lewis	Journal of clinical pathology. Supplement (Association of Clinical Pathologists)	1973
Familial hypercholesterolemia: identification of a defect in the regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase activity associated with overproduction of cholesterol JL Goldstein, MS Brown	Proceedings of the National Academy of Sciences	1973
PLASMA LIPOPROTEINS AND HYPERLIPOPROTEINEMIA A Gustafson, K Berg	Acta Medica Scandinavica	1973
Diagnosis and management of hyperlipoproteinemia in infants and children RI Levy, BM Rifkind	The American Journal of Cardiology	1973
Metabolism of rat plasma very low density lipoprotein S Eisenberg, D Rachmilewitz	Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism	1973
Metabolic fate of rat and human lipoprotein apoproteins in the rat S Eisenberg, HG Windmueller, RI Levy	Journal of lipid research	1973
Lipid Lowering Drugs and Hyperlipidaemia: RI Levy, BM Rifkind	Drugs	1973
Interpretation of Hyperlipidemias WR Harlan, WA Shaw	Critical Reviews in Clinical Laboratory Sciences	1972
Protides of the Biological Fluids PA Small, RH Waldman	Protides of the Biological Fluids	1969
Advances in Lipid Research AM Scanu	Advances in Lipid Research	1965

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