Go to JCI Insight
  • About
  • Editors
  • Consulting Editors
  • For authors
  • Publication ethics
  • Publication alerts by email
  • Advertising
  • Job board
  • Contact
  • Clinical Research and Public Health
  • Current issue
  • Past issues
  • By specialty
    • COVID-19
    • Cardiology
    • Gastroenterology
    • Immunology
    • Metabolism
    • Nephrology
    • Neuroscience
    • Oncology
    • Pulmonology
    • Vascular biology
    • All ...
  • Videos
    • Conversations with Giants in Medicine
    • Video Abstracts
  • Reviews
    • View all reviews ...
    • Complement Biology and Therapeutics (May 2025)
    • Evolving insights into MASLD and MASH pathogenesis and treatment (Apr 2025)
    • Microbiome in Health and Disease (Feb 2025)
    • Substance Use Disorders (Oct 2024)
    • Clonal Hematopoiesis (Oct 2024)
    • Sex Differences in Medicine (Sep 2024)
    • Vascular Malformations (Apr 2024)
    • View all review series ...
  • Viewpoint
  • Collections
    • In-Press Preview
    • Clinical Research and Public Health
    • Research Letters
    • Letters to the Editor
    • Editorials
    • Commentaries
    • Editor's notes
    • Reviews
    • Viewpoints
    • 100th anniversary
    • Top read articles

  • Current issue
  • Past issues
  • Specialties
  • Reviews
  • Review series
  • Conversations with Giants in Medicine
  • Video Abstracts
  • In-Press Preview
  • Clinical Research and Public Health
  • Research Letters
  • Letters to the Editor
  • Editorials
  • Commentaries
  • Editor's notes
  • Reviews
  • Viewpoints
  • 100th anniversary
  • Top read articles
  • About
  • Editors
  • Consulting Editors
  • For authors
  • Publication ethics
  • Publication alerts by email
  • Advertising
  • Job board
  • Contact
Top
  • View PDF
  • Download citation information
  • Send a comment
  • Terms of use
  • Standard abbreviations
  • Need help? Email the journal
  • Top
  • Version history
  • Article usage
  • Citations to this article

Advertisement

Research Article Free access | 10.1172/JCI102858

THE DIRECT MEASUREMENT OF THE EXTRACELLULAR PHASE OF TISSUES

George Nichols Jr., Nancy Nichols, William B. Weil, and William M. Wallace

Department of Pediatrics, Harvard Medical School, Boston, Mass.

Department of Medicine, Harvard Medical School, Boston, Mass.

Children's Medical Center, Boston, Mass.

3

Present address: Peter Bent Brigham Hospital, Boston, Mass.

4

Postdoctorate Fellow, U. S. Public Health Service.

1

This work was supported by grant number H-748 from the National Heart Institute, U. S. Public Health Service.

2

A preliminary report of this investigation appeared in the Proceedings of the 44th Annual Meeting of the American Society for Clinical Investigation, May 1, 1952, J. Clin. Invest., 1952, 31, 652.

Find articles by Nichols, G. in: JCI | PubMed | Google Scholar

Department of Pediatrics, Harvard Medical School, Boston, Mass.

Department of Medicine, Harvard Medical School, Boston, Mass.

Children's Medical Center, Boston, Mass.

3

Present address: Peter Bent Brigham Hospital, Boston, Mass.

4

Postdoctorate Fellow, U. S. Public Health Service.

1

This work was supported by grant number H-748 from the National Heart Institute, U. S. Public Health Service.

2

A preliminary report of this investigation appeared in the Proceedings of the 44th Annual Meeting of the American Society for Clinical Investigation, May 1, 1952, J. Clin. Invest., 1952, 31, 652.

Find articles by Nichols, N. in: JCI | PubMed | Google Scholar

Department of Pediatrics, Harvard Medical School, Boston, Mass.

Department of Medicine, Harvard Medical School, Boston, Mass.

Children's Medical Center, Boston, Mass.

3

Present address: Peter Bent Brigham Hospital, Boston, Mass.

4

Postdoctorate Fellow, U. S. Public Health Service.

1

This work was supported by grant number H-748 from the National Heart Institute, U. S. Public Health Service.

2

A preliminary report of this investigation appeared in the Proceedings of the 44th Annual Meeting of the American Society for Clinical Investigation, May 1, 1952, J. Clin. Invest., 1952, 31, 652.

Find articles by Weil, W. in: JCI | PubMed | Google Scholar

Department of Pediatrics, Harvard Medical School, Boston, Mass.

Department of Medicine, Harvard Medical School, Boston, Mass.

Children's Medical Center, Boston, Mass.

3

Present address: Peter Bent Brigham Hospital, Boston, Mass.

4

Postdoctorate Fellow, U. S. Public Health Service.

1

This work was supported by grant number H-748 from the National Heart Institute, U. S. Public Health Service.

2

A preliminary report of this investigation appeared in the Proceedings of the 44th Annual Meeting of the American Society for Clinical Investigation, May 1, 1952, J. Clin. Invest., 1952, 31, 652.

Find articles by Wallace, W. in: JCI | PubMed | Google Scholar

Published December 1, 1953 - More info

Published in Volume 32, Issue 12 on December 1, 1953
J Clin Invest. 1953;32(12):1299–1308. https://doi.org/10.1172/JCI102858.
© 1953 The American Society for Clinical Investigation
Published December 1, 1953 - Version history
View PDF
Browse pages

Click on an image below to see the page. View PDF of the complete article

icon of scanned page 1299
page 1299
icon of scanned page 1300
page 1300
icon of scanned page 1301
page 1301
icon of scanned page 1302
page 1302
icon of scanned page 1303
page 1303
icon of scanned page 1304
page 1304
icon of scanned page 1305
page 1305
icon of scanned page 1306
page 1306
icon of scanned page 1307
page 1307
icon of scanned page 1308
page 1308
Version history
  • Version 1 (December 1, 1953): No description

Article tools

  • View PDF
  • Download citation information
  • Send a comment
  • Terms of use
  • Standard abbreviations
  • Need help? Email the journal

Metrics

  • Article usage
  • Citations to this article

Go to

  • Top
  • Version history
Advertisement
Advertisement

Copyright © 2025 American Society for Clinical Investigation
ISSN: 0021-9738 (print), 1558-8238 (online)

Sign up for email alerts