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Research Article Free access | 10.1172/JCI101978

STUDIES ON THE CHEMOTHERAPY OF THE HUMAN MALARIAS. IV. THE METABOLISM OF CINCHONINE IN RELATION TO ITS ANTIMALARIAL ACTIVITY

David P. Earle Jr., William J. Welch, and James A. Shannon

Department of Medicine, New York University College of Medicine, New York City

Research Service, Third [New York University] Medical Division, Goldwater Memorial Hospital, New York City

4

Captain, MC, AUS.

1

The work described in this paper was done under a contract, recommended by the Committee on Medical Research, between the Office of Scientific Research and Development and New York University.

2

Portions of this work were presented at the meetings of the Federation of American Societies for Experimental Biology, March 11-15, 1946, Federation Proc., 1946, 5, 175 and 214, and were also discussed in a Harvey Lecture by Dr. James A. Shannon, Oct. 25, 1945. Permission to use Table VI has been obtained from the Harvey Society.

3

The authors express their thanks to the Malaria Study Section of the National Institute of Health for editorial assistance and for arrangements in regard to the publication of this paper. They are also grateful to the Abbott Laboratories, E. I. du Pont de Nemours and Company, Inc., E. R. Squibb and Sons, Eli Lilly and Company, Sharp and Dohme, and Wyeth, Inc., for contributing toward the publication costs.

Find articles by Earle, D. in: JCI | PubMed | Google Scholar

Department of Medicine, New York University College of Medicine, New York City

Research Service, Third [New York University] Medical Division, Goldwater Memorial Hospital, New York City

4

Captain, MC, AUS.

1

The work described in this paper was done under a contract, recommended by the Committee on Medical Research, between the Office of Scientific Research and Development and New York University.

2

Portions of this work were presented at the meetings of the Federation of American Societies for Experimental Biology, March 11-15, 1946, Federation Proc., 1946, 5, 175 and 214, and were also discussed in a Harvey Lecture by Dr. James A. Shannon, Oct. 25, 1945. Permission to use Table VI has been obtained from the Harvey Society.

3

The authors express their thanks to the Malaria Study Section of the National Institute of Health for editorial assistance and for arrangements in regard to the publication of this paper. They are also grateful to the Abbott Laboratories, E. I. du Pont de Nemours and Company, Inc., E. R. Squibb and Sons, Eli Lilly and Company, Sharp and Dohme, and Wyeth, Inc., for contributing toward the publication costs.

Find articles by Welch, W. in: JCI | PubMed | Google Scholar

Department of Medicine, New York University College of Medicine, New York City

Research Service, Third [New York University] Medical Division, Goldwater Memorial Hospital, New York City

4

Captain, MC, AUS.

1

The work described in this paper was done under a contract, recommended by the Committee on Medical Research, between the Office of Scientific Research and Development and New York University.

2

Portions of this work were presented at the meetings of the Federation of American Societies for Experimental Biology, March 11-15, 1946, Federation Proc., 1946, 5, 175 and 214, and were also discussed in a Harvey Lecture by Dr. James A. Shannon, Oct. 25, 1945. Permission to use Table VI has been obtained from the Harvey Society.

3

The authors express their thanks to the Malaria Study Section of the National Institute of Health for editorial assistance and for arrangements in regard to the publication of this paper. They are also grateful to the Abbott Laboratories, E. I. du Pont de Nemours and Company, Inc., E. R. Squibb and Sons, Eli Lilly and Company, Sharp and Dohme, and Wyeth, Inc., for contributing toward the publication costs.

Find articles by Shannon, J. in: JCI | PubMed | Google Scholar

Published May 1, 1948 - More info

Published in Volume 27, Issue 3 on May 1, 1948
J Clin Invest. 1948;27(3):87–92. https://doi.org/10.1172/JCI101978.
© 1948 The American Society for Clinical Investigation
Published May 1, 1948 - Version history
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