Go to JCI Insight
  • About
  • Editors
  • Consulting Editors
  • For authors
  • Publication ethics
  • Publication alerts by email
  • Advertising
  • Job board
  • Contact
  • Clinical Research and Public Health
  • Current issue
  • Past issues
  • By specialty
    • COVID-19
    • Cardiology
    • Gastroenterology
    • Immunology
    • Metabolism
    • Nephrology
    • Neuroscience
    • Oncology
    • Pulmonology
    • Vascular biology
    • All ...
  • Videos
    • Conversations with Giants in Medicine
    • Video Abstracts
  • Reviews
    • View all reviews ...
    • Complement Biology and Therapeutics (May 2025)
    • Evolving insights into MASLD and MASH pathogenesis and treatment (Apr 2025)
    • Microbiome in Health and Disease (Feb 2025)
    • Substance Use Disorders (Oct 2024)
    • Clonal Hematopoiesis (Oct 2024)
    • Sex Differences in Medicine (Sep 2024)
    • Vascular Malformations (Apr 2024)
    • View all review series ...
  • Viewpoint
  • Collections
    • In-Press Preview
    • Clinical Research and Public Health
    • Research Letters
    • Letters to the Editor
    • Editorials
    • Commentaries
    • Editor's notes
    • Reviews
    • Viewpoints
    • 100th anniversary
    • Top read articles

  • Current issue
  • Past issues
  • Specialties
  • Reviews
  • Review series
  • Conversations with Giants in Medicine
  • Video Abstracts
  • In-Press Preview
  • Clinical Research and Public Health
  • Research Letters
  • Letters to the Editor
  • Editorials
  • Commentaries
  • Editor's notes
  • Reviews
  • Viewpoints
  • 100th anniversary
  • Top read articles
  • About
  • Editors
  • Consulting Editors
  • For authors
  • Publication ethics
  • Publication alerts by email
  • Advertising
  • Job board
  • Contact
Top
  • View PDF
  • Download citation information
  • Send a comment
  • Terms of use
  • Standard abbreviations
  • Need help? Email the journal
  • Top
  • Version history
  • Article usage
  • Citations to this article (42)

Advertisement

Research Article Free access | 10.1172/JCI101977

STUDIES ON THE CHEMOTHERAPY OF THE HUMAN MALARIAS. III. THE PHYSIOLOGICAL DISPOSITION AND ANTIMALARIAL ACTIVITY OF THE CINCHONA ALKALOIDS

John V. Taggart, David P. Earle Jr., Robert W. Berliner, Charles G. Zubrod, William J. Welch, Nancy Bowman Wise, Edmond F. Schroeder, Irving M. London, and James A. Shannon

Department of Medicine, New York University College of Medicine, New York City

Research Service, Third [New York University] Medical Division, Goldwater Memorial Hospital, New York City

4

Captain, MC, AUS.

1

The work described in this paper was done under a contract, recommended by the Committee on Medical Research, between the Office of Scientific Research and Development and New York University.

2

Portions of this work were presented at the meetings of the Federation of American Societies for Experimental Biology, March 11-15, 1946, Federation Proc., 1946, 5, 206 and 216.

3

The authors express their thanks to the Malaria Study Section of the National Institute of Health for editorial assistance and for arrangements in regard to the publication of this paper. They are also grateful to the Abbott Laboratories, E. I. du Pont de Nemours and Company, Inc., E. R. Squibb and Sons, Eli Lilly and Company, Sharp and Dohme, and Wyeth, Inc., for contributing toward the publication costs.

Find articles by Taggart, J. in: JCI | PubMed | Google Scholar

Department of Medicine, New York University College of Medicine, New York City

Research Service, Third [New York University] Medical Division, Goldwater Memorial Hospital, New York City

4

Captain, MC, AUS.

1

The work described in this paper was done under a contract, recommended by the Committee on Medical Research, between the Office of Scientific Research and Development and New York University.

2

Portions of this work were presented at the meetings of the Federation of American Societies for Experimental Biology, March 11-15, 1946, Federation Proc., 1946, 5, 206 and 216.

3

The authors express their thanks to the Malaria Study Section of the National Institute of Health for editorial assistance and for arrangements in regard to the publication of this paper. They are also grateful to the Abbott Laboratories, E. I. du Pont de Nemours and Company, Inc., E. R. Squibb and Sons, Eli Lilly and Company, Sharp and Dohme, and Wyeth, Inc., for contributing toward the publication costs.

Find articles by Earle, D. in: JCI | PubMed | Google Scholar

Department of Medicine, New York University College of Medicine, New York City

Research Service, Third [New York University] Medical Division, Goldwater Memorial Hospital, New York City

4

Captain, MC, AUS.

1

The work described in this paper was done under a contract, recommended by the Committee on Medical Research, between the Office of Scientific Research and Development and New York University.

2

Portions of this work were presented at the meetings of the Federation of American Societies for Experimental Biology, March 11-15, 1946, Federation Proc., 1946, 5, 206 and 216.

3

The authors express their thanks to the Malaria Study Section of the National Institute of Health for editorial assistance and for arrangements in regard to the publication of this paper. They are also grateful to the Abbott Laboratories, E. I. du Pont de Nemours and Company, Inc., E. R. Squibb and Sons, Eli Lilly and Company, Sharp and Dohme, and Wyeth, Inc., for contributing toward the publication costs.

Find articles by Berliner, R. in: JCI | PubMed | Google Scholar

Department of Medicine, New York University College of Medicine, New York City

Research Service, Third [New York University] Medical Division, Goldwater Memorial Hospital, New York City

4

Captain, MC, AUS.

1

The work described in this paper was done under a contract, recommended by the Committee on Medical Research, between the Office of Scientific Research and Development and New York University.

2

Portions of this work were presented at the meetings of the Federation of American Societies for Experimental Biology, March 11-15, 1946, Federation Proc., 1946, 5, 206 and 216.

3

The authors express their thanks to the Malaria Study Section of the National Institute of Health for editorial assistance and for arrangements in regard to the publication of this paper. They are also grateful to the Abbott Laboratories, E. I. du Pont de Nemours and Company, Inc., E. R. Squibb and Sons, Eli Lilly and Company, Sharp and Dohme, and Wyeth, Inc., for contributing toward the publication costs.

Find articles by Zubrod, C. in: JCI | PubMed | Google Scholar

Department of Medicine, New York University College of Medicine, New York City

Research Service, Third [New York University] Medical Division, Goldwater Memorial Hospital, New York City

4

Captain, MC, AUS.

1

The work described in this paper was done under a contract, recommended by the Committee on Medical Research, between the Office of Scientific Research and Development and New York University.

2

Portions of this work were presented at the meetings of the Federation of American Societies for Experimental Biology, March 11-15, 1946, Federation Proc., 1946, 5, 206 and 216.

3

The authors express their thanks to the Malaria Study Section of the National Institute of Health for editorial assistance and for arrangements in regard to the publication of this paper. They are also grateful to the Abbott Laboratories, E. I. du Pont de Nemours and Company, Inc., E. R. Squibb and Sons, Eli Lilly and Company, Sharp and Dohme, and Wyeth, Inc., for contributing toward the publication costs.

Find articles by Welch, W. in: JCI | PubMed | Google Scholar

Department of Medicine, New York University College of Medicine, New York City

Research Service, Third [New York University] Medical Division, Goldwater Memorial Hospital, New York City

4

Captain, MC, AUS.

1

The work described in this paper was done under a contract, recommended by the Committee on Medical Research, between the Office of Scientific Research and Development and New York University.

2

Portions of this work were presented at the meetings of the Federation of American Societies for Experimental Biology, March 11-15, 1946, Federation Proc., 1946, 5, 206 and 216.

3

The authors express their thanks to the Malaria Study Section of the National Institute of Health for editorial assistance and for arrangements in regard to the publication of this paper. They are also grateful to the Abbott Laboratories, E. I. du Pont de Nemours and Company, Inc., E. R. Squibb and Sons, Eli Lilly and Company, Sharp and Dohme, and Wyeth, Inc., for contributing toward the publication costs.

Find articles by Wise, N. in: JCI | PubMed | Google Scholar

Department of Medicine, New York University College of Medicine, New York City

Research Service, Third [New York University] Medical Division, Goldwater Memorial Hospital, New York City

4

Captain, MC, AUS.

1

The work described in this paper was done under a contract, recommended by the Committee on Medical Research, between the Office of Scientific Research and Development and New York University.

2

Portions of this work were presented at the meetings of the Federation of American Societies for Experimental Biology, March 11-15, 1946, Federation Proc., 1946, 5, 206 and 216.

3

The authors express their thanks to the Malaria Study Section of the National Institute of Health for editorial assistance and for arrangements in regard to the publication of this paper. They are also grateful to the Abbott Laboratories, E. I. du Pont de Nemours and Company, Inc., E. R. Squibb and Sons, Eli Lilly and Company, Sharp and Dohme, and Wyeth, Inc., for contributing toward the publication costs.

Find articles by Schroeder, E. in: JCI | PubMed | Google Scholar

Department of Medicine, New York University College of Medicine, New York City

Research Service, Third [New York University] Medical Division, Goldwater Memorial Hospital, New York City

4

Captain, MC, AUS.

1

The work described in this paper was done under a contract, recommended by the Committee on Medical Research, between the Office of Scientific Research and Development and New York University.

2

Portions of this work were presented at the meetings of the Federation of American Societies for Experimental Biology, March 11-15, 1946, Federation Proc., 1946, 5, 206 and 216.

3

The authors express their thanks to the Malaria Study Section of the National Institute of Health for editorial assistance and for arrangements in regard to the publication of this paper. They are also grateful to the Abbott Laboratories, E. I. du Pont de Nemours and Company, Inc., E. R. Squibb and Sons, Eli Lilly and Company, Sharp and Dohme, and Wyeth, Inc., for contributing toward the publication costs.

Find articles by London, I. in: JCI | PubMed | Google Scholar

Department of Medicine, New York University College of Medicine, New York City

Research Service, Third [New York University] Medical Division, Goldwater Memorial Hospital, New York City

4

Captain, MC, AUS.

1

The work described in this paper was done under a contract, recommended by the Committee on Medical Research, between the Office of Scientific Research and Development and New York University.

2

Portions of this work were presented at the meetings of the Federation of American Societies for Experimental Biology, March 11-15, 1946, Federation Proc., 1946, 5, 206 and 216.

3

The authors express their thanks to the Malaria Study Section of the National Institute of Health for editorial assistance and for arrangements in regard to the publication of this paper. They are also grateful to the Abbott Laboratories, E. I. du Pont de Nemours and Company, Inc., E. R. Squibb and Sons, Eli Lilly and Company, Sharp and Dohme, and Wyeth, Inc., for contributing toward the publication costs.

Find articles by Shannon, J. in: JCI | PubMed | Google Scholar

Published May 1, 1948 - More info

Published in Volume 27, Issue 3 on May 1, 1948
J Clin Invest. 1948;27(3):80–86. https://doi.org/10.1172/JCI101977.
© 1948 The American Society for Clinical Investigation
Published May 1, 1948 - Version history
View PDF
Browse pages

Click on an image below to see the page. View PDF of the complete article

icon of scanned page 80
page 80
icon of scanned page 81
page 81
icon of scanned page 82
page 82
icon of scanned page 83
page 83
icon of scanned page 84
page 84
icon of scanned page 85
page 85
icon of scanned page 86
page 86
Version history
  • Version 1 (May 1, 1948): No description

Article tools

  • View PDF
  • Download citation information
  • Send a comment
  • Terms of use
  • Standard abbreviations
  • Need help? Email the journal

Metrics

  • Article usage
  • Citations to this article (42)

Go to

  • Top
  • Version history
Advertisement
Advertisement

Copyright © 2025 American Society for Clinical Investigation
ISSN: 0021-9738 (print), 1558-8238 (online)

Sign up for email alerts