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  • Volume 110, Issue 10
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In This Issue
/articles/view/119962
Published November 15, 2002
Citation Information: J Clin Invest. 2002;110(10):1373-1373. https://doi.org/10.1172/JCI119962.
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In This Issue

Abstract

Authors

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Perspectives
Deciphering the genesis and fate of amyloid β-protein yields novel therapies for Alzheimer disease
Dennis J. Selkoe
Dennis J. Selkoe
Published November 15, 2002
Citation Information: J Clin Invest. 2002;110(10):1375-1381. https://doi.org/10.1172/JCI16783.
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Translational control in the endoplasmic reticulum stress response
David Ron
David Ron
Published November 15, 2002
Citation Information: J Clin Invest. 2002;110(10):1383-1388. https://doi.org/10.1172/JCI16784.
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Orchestrating the unfolded protein response in health and disease
Randal J. Kaufman
Randal J. Kaufman
Published November 15, 2002
Citation Information: J Clin Invest. 2002;110(10):1389-1398. https://doi.org/10.1172/JCI16886.
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Orchestrating the unfolded protein response in health and disease

Abstract

Perspective

Authors

Randal J. Kaufman

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Commentaries
Manipulating the environment of cancer cells in bone: a novel therapeutic approach
T. John Martin
T. John Martin
Published November 15, 2002
Citation Information: J Clin Invest. 2002;110(10):1399-1401. https://doi.org/10.1172/JCI17124.
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Misfolded, protease-resistant proteins in animal models and human neurodegenerative disease
Dennis W. Dickson
Dennis W. Dickson
Published November 15, 2002
Citation Information: J Clin Invest. 2002;110(10):1403-1405. https://doi.org/10.1172/JCI17164.
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IFN-γ suspends the killing license of anti-tumor CTLs
Aron E. Lukacher
Aron E. Lukacher
Published November 15, 2002
Citation Information: J Clin Invest. 2002;110(10):1407-1409. https://doi.org/10.1172/JCI17209.
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IFN-γ suspends the killing license of anti-tumor CTLs

Abstract

Commentary

Authors

Aron E. Lukacher

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Arginine: an unusual dietary requirement of pre-B lymphocytes?
Tucker W. LeBien
Tucker W. LeBien
Published November 15, 2002
Citation Information: J Clin Invest. 2002;110(10):1411-1413. https://doi.org/10.1172/JCI17210.
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Arginine: an unusual dietary requirement of pre-B lymphocytes?

Abstract

Commentary

Authors

Tucker W. LeBien

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Adoptive therapy with CD8+ T cells: it may get by with a little help from its friends
William Y. Ho, … , Cassian Yee, Philip D. Greenberg
William Y. Ho, … , Cassian Yee, Philip D. Greenberg
Published November 15, 2002
Citation Information: J Clin Invest. 2002;110(10):1415-1417. https://doi.org/10.1172/JCI17214.
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Adoptive therapy with CD8+ T cells: it may get by with a little help from its friends

Abstract

Commentary

Authors

William Y. Ho, Cassian Yee, Philip D. Greenberg

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Research Articles
Osteoclasts are essential for TNF-α–mediated joint destruction
Kurt Redlich, … , Erwin F. Wagner, Georg Schett
Kurt Redlich, … , Erwin F. Wagner, Georg Schett
Published November 15, 2002
Citation Information: J Clin Invest. 2002;110(10):1419-1427. https://doi.org/10.1172/JCI15582.
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Osteoclasts are essential for TNF-α–mediated joint destruction

Abstract

Research Article

Authors

Kurt Redlich, Silvia Hayer, Romeo Ricci, Jean-Pierre David, Makiyeh Tohidast-Akrad, George Kollias, Günter Steiner, Josef S. Smolen, Erwin F. Wagner, Georg Schett

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Misfolded proteinase K–resistant hyperphosphorylated α-synuclein in aged transgenic mice with locomotor deterioration and in human α-synucleinopathies
Manuela Neumann, … , Hans A. Kretzschmar, Christian Haass
Manuela Neumann, … , Hans A. Kretzschmar, Christian Haass
Published November 15, 2002
Citation Information: J Clin Invest. 2002;110(10):1429-1439. https://doi.org/10.1172/JCI15777.
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Misfolded proteinase K–resistant hyperphosphorylated α-synuclein in aged transgenic mice with locomotor deterioration and in human α-synucleinopathies

Abstract

Research Article

Authors

Manuela Neumann, Philipp J. Kahle, Benoit I. Giasson, Laurence Ozmen, Edilio Borroni, Will Spooren, Veronika Müller, Sabine Odoy, Hideo Fujiwara, Masato Hasegawa, Takeshi Iwatsubo, John Q. Trojanowski, Hans A. Kretzschmar, Christian Haass

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Resident lung antigen-presenting cells have the capacity to promote Th2 T cell differentiation in situ
Stephanie L. Constant, … , Nancy H. Ruddle, Kim Bottomly
Stephanie L. Constant, … , Nancy H. Ruddle, Kim Bottomly
Published November 15, 2002
Citation Information: J Clin Invest. 2002;110(10):1441-1448. https://doi.org/10.1172/JCI16109.
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Resident lung antigen-presenting cells have the capacity to promote Th2 T cell differentiation in situ

Abstract

Research Article

Authors

Stephanie L. Constant, Jennifer L. Brogdon, Damani A. Piggott, Christina A. Herrick, Irene Visintin, Nancy H. Ruddle, Kim Bottomly

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The mouse mahoganoid coat color mutation disrupts a novel C3HC4 RING domain protein
Loan K. Phan, … , Wendy K. Chung, Rudolph L. Leibel
Loan K. Phan, … , Wendy K. Chung, Rudolph L. Leibel
Published November 15, 2002
Citation Information: J Clin Invest. 2002;110(10):1449-1459. https://doi.org/10.1172/JCI16131.
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The mouse mahoganoid coat color mutation disrupts a novel C3HC4 RING domain protein

Abstract

Research Article

Authors

Loan K. Phan, Feng Lin, Charles A. LeDuc, Wendy K. Chung, Rudolph L. Leibel

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The Staphylococcus aureus Map protein is an immunomodulator that interferes with T cell–mediated responses
Lawrence Y. Lee, … , Damien McDevitt, Eric L. Brown
Lawrence Y. Lee, … , Damien McDevitt, Eric L. Brown
Published November 15, 2002
Citation Information: J Clin Invest. 2002;110(10):1461-1471. https://doi.org/10.1172/JCI16318.
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The Staphylococcus aureus Map protein is an immunomodulator that interferes with T cell–mediated responses

Abstract

Research Article

Authors

Lawrence Y. Lee, Yuko J. Miyamoto, Bradley W. McIntyre, Magnus Höök, Kirk W. McCrea, Damien McDevitt, Eric L. Brown

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Target organ localization of memory CD4+ T cells in patients with chronic beryllium disease
Andrew P. Fontenot, … , Lee S. Newman, Brian L. Kotzin
Andrew P. Fontenot, … , Lee S. Newman, Brian L. Kotzin
Published November 15, 2002
Citation Information: J Clin Invest. 2002;110(10):1473-1482. https://doi.org/10.1172/JCI15846.
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Target organ localization of memory CD4+ T cells in patients with chronic beryllium disease

Abstract

Research Article

Authors

Andrew P. Fontenot, Scott J. Canavera, Laia Gharavi, Lee S. Newman, Brian L. Kotzin

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Hyperinsulinemia, glucose intolerance, and dyslipidemia induced by acute inhibition of phosphoinositide 3-kinase signaling in the liver
Kazuaki Miyake, … , Hiroshi Sakaue, Masato Kasuga
Kazuaki Miyake, … , Hiroshi Sakaue, Masato Kasuga
Published November 15, 2002
Citation Information: J Clin Invest. 2002;110(10):1483-1491. https://doi.org/10.1172/JCI15880.
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Hyperinsulinemia, glucose intolerance, and dyslipidemia induced by acute inhibition of phosphoinositide 3-kinase signaling in the liver

Abstract

Research Article

Authors

Kazuaki Miyake, Wataru Ogawa, Michihiro Matsumoto, Takehiro Nakamura, Hiroshi Sakaue, Masato Kasuga

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Rescue of CD8 T cell–mediated antimicrobial immunity with a nonspecific inflammatory stimulus
Roman A. Tuma, … , Ingrid Leiner, Eric G. Pamer
Roman A. Tuma, … , Ingrid Leiner, Eric G. Pamer
Published November 15, 2002
Citation Information: J Clin Invest. 2002;110(10):1493-1501. https://doi.org/10.1172/JCI16356.
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Rescue of CD8 T cell–mediated antimicrobial immunity with a nonspecific inflammatory stimulus

Abstract

Research Article

Authors

Roman A. Tuma, Rielle Giannino, Patrick Guirnalda, Ingrid Leiner, Eric G. Pamer

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Opposing roles of STAT1 and STAT3 in T cell–mediated hepatitis: regulation by SOCS
Feng Hong, … , Van-Anh Nguyen, Bin Gao
Feng Hong, … , Van-Anh Nguyen, Bin Gao
Published November 15, 2002
Citation Information: J Clin Invest. 2002;110(10):1503-1513. https://doi.org/10.1172/JCI15841.
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Opposing roles of STAT1 and STAT3 in T cell–mediated hepatitis: regulation by SOCS

Abstract

Research Article

Authors

Feng Hong, Barbara Jaruga, Won Ho Kim, Svetlana Radaeva, Osama N. El-Assal, Zhigang Tian, Van-Anh Nguyen, Bin Gao

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IFN-γ protects short-term ovarian carcinoma cell lines from CTL lysis via a CD94/NKG2A-dependent mechanism
Karl-Johan Malmberg, … , Jelena Levitskaya, Rolf Kiessling
Karl-Johan Malmberg, … , Jelena Levitskaya, Rolf Kiessling
Published November 15, 2002
Citation Information: J Clin Invest. 2002;110(10):1515-1523. https://doi.org/10.1172/JCI15564.
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IFN-γ protects short-term ovarian carcinoma cell lines from CTL lysis via a CD94/NKG2A-dependent mechanism

Abstract

Research Article

Authors

Karl-Johan Malmberg, Victor Levitsky, Håkan Norell, Cristina Teixeira de Matos, Mattias Carlsten, Kjell Schedvins, Hodjattallah Rabbani, Alessandro Moretta, Kalle Söderström, Jelena Levitskaya, Rolf Kiessling

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Disruption of tissue-type plasminogen activator gene in mice reduces renal interstitial fibrosis in obstructive nephropathy
Junwei Yang, … , Kari Nejak, Youhua Liu
Junwei Yang, … , Kari Nejak, Youhua Liu
Published November 15, 2002
Citation Information: J Clin Invest. 2002;110(10):1525-1538. https://doi.org/10.1172/JCI16219.
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Disruption of tissue-type plasminogen activator gene in mice reduces renal interstitial fibrosis in obstructive nephropathy

Abstract

Research Article

Authors

Junwei Yang, Ryan W. Shultz, Wendy M. Mars, Rodney E. Wegner, Yingjian Li, Chunsun Dai, Kari Nejak, Youhua Liu

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Arginine deficiency affects early B cell maturation and lymphoid organ development in transgenic mice
Wouter J. de Jonge, … , Marinus C. Lamers, Wouter H. Lamers
Wouter J. de Jonge, … , Marinus C. Lamers, Wouter H. Lamers
Published November 15, 2002
Citation Information: J Clin Invest. 2002;110(10):1539-1548. https://doi.org/10.1172/JCI16143.
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Arginine deficiency affects early B cell maturation and lymphoid organ development in transgenic mice

Abstract

Research Article

Authors

Wouter J. de Jonge, Karin L. Kwikkers, Anje A. te Velde, Sander J.H. van Deventer, Martijn A. Nolte, Reina E. Mebius, Jan M. Ruijter, Marinus C. Lamers, Wouter H. Lamers

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Modulation of tumor growth by inhibitory Fcγ receptor expressed by human melanoma cells
Lydie Cassard, … , Wolf H. Fridman, Catherine Sautès-Fridman
Lydie Cassard, … , Wolf H. Fridman, Catherine Sautès-Fridman
Published November 15, 2002
Citation Information: J Clin Invest. 2002;110(10):1549-1557. https://doi.org/10.1172/JCI15454.
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Modulation of tumor growth by inhibitory Fcγ receptor expressed by human melanoma cells

Abstract

Research Article

Authors

Lydie Cassard, Joël F.G. Cohen-Solal, Annie Galinha, Xavier Sastre-Garau, Claire Mathiot, Jérôme Galon, Thierry Dorval, Alain Bernheim, Wolf H. Fridman, Catherine Sautès-Fridman

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Guanosine nucleotides inhibit different syndromes of PTHrP excess caused by human cancers in vivo
Wolfgang E. Gallwitz, … , Theresa A. Guise, Gregory R. Mundy
Wolfgang E. Gallwitz, … , Theresa A. Guise, Gregory R. Mundy
Published November 15, 2002
Citation Information: J Clin Invest. 2002;110(10):1559-1572. https://doi.org/10.1172/JCI11936.
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Guanosine nucleotides inhibit different syndromes of PTHrP excess caused by human cancers in vivo

Abstract

Research Article

Authors

Wolfgang E. Gallwitz, Theresa A. Guise, Gregory R. Mundy

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Corrigendum
Craniosynostosis in transgenic mice overexpressing Nell-1
Xinli Zhang, … , Naoaki Saito, Kang Ting
Xinli Zhang, … , Naoaki Saito, Kang Ting
Published November 15, 2002
Citation Information: J Clin Invest. 2002;110(10):1573-1573. https://doi.org/10.1172/JCI15375C1.
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Craniosynostosis in transgenic mice overexpressing Nell-1

Abstract

Corrigendum

Authors

Xinli Zhang, Shun’ichi Kuroda, Dale Carpenter, Ichiro Nishimura, Chia Soo, Rex Moats, Keisuke Iida, Eric Wisner, Fei-Ya Hu, Steve Miao, Steve Beanes, Catherine Dang, Heleni Vastardis, Michael Longaker, Katsuyuki Tanizawa, Norihiro Kanayama, Naoaki Saito, Kang Ting

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