Cardiology

Overexpression of ABCG5 and ABCG8 promotes biliary cholesterol secretion and reduces fractional absorption of dietary cholesterol
Liqing Yu, … , Jonathan C. Cohen, Helen H. Hobbs
Liqing Yu, … , Jonathan C. Cohen, Helen H. Hobbs
Published September 1, 2002
Citation Information: J Clin Invest. 2002;110(5):671-680. https://doi.org/10.1172/JCI16001.
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Overexpression of ABCG5 and ABCG8 promotes biliary cholesterol secretion and reduces fractional absorption of dietary cholesterol

Abstract

Research Article

Authors

Liqing Yu, Jia Li-Hawkins, Robert E. Hammer, Knut E. Berge, Jay D. Horton, Jonathan C. Cohen, Helen H. Hobbs

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Increased ABCA1 activity protects against atherosclerosis
Roshni R. Singaraja, … , Bart Staels, Michael R. Hayden
Roshni R. Singaraja, … , Bart Staels, Michael R. Hayden
Published July 1, 2002
Citation Information: J Clin Invest. 2002;110(1):35-42. https://doi.org/10.1172/JCI15748.
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Increased ABCA1 activity protects against atherosclerosis

Abstract

Research Article

Authors

Roshni R. Singaraja, Catherine Fievet, Graciela Castro, Erick R. James, Nathalie Hennuyer, Susanne M. Clee, Nagat Bissada, Jonathan C. Choy, Jean-Charles Fruchart, Bruce M. McManus, Bart Staels, Michael R. Hayden

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Calpain-6 mediates atherogenic macrophage function
In this episode, Takuro Miyazaki and colleagues reveal that elevation of calpain-6 in macrophages promotes atherogenic functions by disrupting CWC22/EJC/Rac1 signaling.
Published August 15, 2016
Author's TakeCardiology
Kruppel-like factor 4 keeps the heart healthy
Xudong Liao and colleagues identify KLF4 as an important regulator of mitochondrial development and function in the heart…
Published August 4, 2015
Scientific Show StopperCardiology
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Oxidation impedes cardioprotection
Taishi Nakamura and colleagues reveal that oxidation prevents the beneficial effects of PKG1α in response to cardiac stress…
Published May 4, 2015
Scientific Show StopperCardiology
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