Go to
JCI Insight
Citations to this article
Peter S. Mortimer, Stanley G. Rockson
Published March 3, 2014
Citation Information: J Clin Invest. 2014;124(3):915-921. https://doi.org/10.1172/JCI71608.
Citation Information: J Clin Invest. 2014;124(3):915-921. https://doi.org/10.1172/JCI71608.
Abstract
The lymphatic system is fundamentally important to cardiovascular disease, infection and immunity, cancer, and probably obesity — the four major challenges in healthcare in the 21st century. This Review will consider the manner in which new knowledge of lymphatic genes and molecular mechanisms has demonstrated that lymphatic dysfunction should no longer be considered a passive bystander in disease but rather an active player in many pathological processes and, therefore, a genuine target for future therapeutic developments. The specific roles of the lymphatic system in edema, genetic aspects of primary lymphedema, infection (cellulitis/erysipelas), Crohn’s disease, obesity, cancer, and cancer-related lymphedema are highlighted.
Authors
Peter S. Mortimer, Stanley G. Rockson
Total citations by year
Citation information
Citations to this article (124)
| Title and authors | Publication | Year |
|---|---|---|
|
Direct specification of lymphatic endothelium from mesenchymal progenitors
Lupu IE, Grainger DE, Kirschnick N, Weischer S, Zhao E, Martinez-Corral I, Schoofs H, Vanhollebeke M, Jones G, Godwin J, Forrow A, Lahmann I, Riley PR, Zobel T, Alitalo K, Mäkinen T, Kiefer F, Stone OA |
Nature Cardiovascular Research | 2025 |
|
The prognostic effect and mechanism of erysipelas in cancer-associated lymphedema
Li P, Zhao Z, Sun Y, Xia S, Shen W |
Scientific Reports | 2025 |
|
15-Lipoxygenase promotes resolution of inflammation in lymphedema by controlling T(reg) cell function through IFN-β.
Zamora A, Nougué M, Verdu L, Balzan E, Draia-Nicolau T, Benuzzi E, Pujol F, Baillif V, Lacazette E, Morfoisse F, Galitzky J, Bouloumié A, Dubourdeau M, Chaput B, Fazilleau N, Malloizel-Delaunay J, Bura-Rivière A, Prats AC, Garmy-Susini B |
Nature Communications | 2024 |
|
Apelin-VEGF-C mRNA delivery as therapeutic for the treatment of secondary lymphedema.
Creff J, Lamaa A, Benuzzi E, Balzan E, Pujol F, Draia-Nicolau T, Nougué M, Verdu L, Morfoisse F, Lacazette E, Valet P, Chaput B, Gross F, Gayon R, Bouillé P, Malloizel-Delaunay J, Bura-Rivière A, Prats AC, Garmy-Susini B |
EMBO Molecular Medicine | 2024 |
|
Sleep quality and lymphedema in breast cancer survivors: a mixed method analysis.
Bock K, Peltzer J, Liu W, Colgrove Y, Smirnova I, Siengsukon C |
Journal of Cancer Survivorship | 2024 |
|
Limb Volume Measurements: A Comparison of Circumferential Techniques and Optoelectronic Systems against Water Displacement
Farina G, Galli M, Borsari L, Aliverti A, Paraskevopoulos IT, LoMauro A |
Bioengineering | 2024 |
|
The lymphedema patient experience within the healthcare system: a cross-sectional epidemiologic assessment.
Bowman C, Rockson SG |
Scientific Reports | 2024 |
|
Micromassage Compression Leggings Associated with Physical Exercise: Pilot Study and Example of Evaluation of the Clinical and Instrumental Effectiveness of Conservative Treatment in Lipedema.
Ricolfi L, Reverdito V, Gabriele G, Bortolon M, Macherelli I, Haag P, De Santis N, Guerriero M, Patton L |
Life (Basel, Switzerland) | 2024 |
|
Longitudinal assessment of health-related quality of life and clinical outcomes with at home advanced pneumatic compression treatment of lower extremity lymphedema
Padberg FT Jr, Ucuzian A, Dosluoglu H, Jacobowitz G, O'Donnell TF |
Journal of Vascular Surgery: Venous and Lymphatic Disorders | 2024 |
|
Congestive lower extremity failure: An educational model for improved understanding of phlebolymphedema
Chuback JA, Melin MM, Massey HT, Gloviczki ML |
Journal of Vascular Surgery: Venous and Lymphatic Disorders | 2024 |
|
Leukocyte-Lymphatic Intersections during Cardiac Inflammation
Glinton K, Thakkar AV, Jones R, Inui H, Ge ZD, Thorp EB |
Journal of molecular and cellular cardiology | 2024 |
|
Development and application of a novel cervical lymph collection method to assess lymphatic transport in rats
Hoang TA, Cao E, Gracia G, Nicolazzo JA, Trevaskis NL |
Frontiers in pharmacology | 2023 |
|
Lymphatic Intervention, the Frontline of Modern Lymphatic Medicine: Part I. History, Anatomy, Physiology, and Diagnostic Imaging of the Lymphatic System
Hur S, Kim J, Ratnam L, Itkin M |
Korean Journal of Radiology | 2023 |
|
Mapping the lymphatic system across body scales and expertise domains: A report from the 2021 National Heart, Lung, and Blood Institute workshop at the Boston Lymphatic Symposium
Singhal D, Börner K, Chaikof EL, Detmar M, Hollmén M, Iliff JJ, Itkin M, Makinen T, Oliver G, Padera TP, Quardokus EM, Radtke AJ, Suami H, Weber GM, Rovira II, Muratoglu SC, Galis ZS |
Frontiers in physiology | 2023 |
|
Effect of valve spacing on peristaltic pumping
Wolf KT, Poorghani A, Dixon JB, Alexeev A |
Bioinspiration & Biomimetics | 2023 |
|
Improving the Assessment and Diagnosis of Breast Lymphedema after Treatment for Breast Cancer.
Riches K, Cheung KL, Keeley V |
Cancers | 2023 |
|
A2AR-mediated lymphangiogenesis via VEGFR2 signaling prevents salt-sensitive hypertension.
Zhuang T, Lei Y, Chang JJ, Zhou YP, Li Y, Li YX, Yang YF, Chen MH, Meng T, Fu SM, Huang LH, Cheang WS, Cooke JP, Dong ZH, Bai YN, Ruan CC |
European Heart Journal | 2023 |
|
A dual-clock-driven model of lymphatic muscle cell pacemaking to emulate knock-out of Ano1 or IP3R
Hancock EJ, Zawieja SD, Macaskill C, Davis MJ, Bertram CD |
The Journal of General Physiology | 2023 |
|
Etiology and treatment of cancer-related secondary lymphedema.
Bernas M, Al-Ghadban S, Thiadens SRJ, Ashforth K, Lin WC, Safa B, Buntic R, Paukshto M, Rovnaya A, McNeely ML |
Clinical & Experimental Metastasis | 2023 |
|
Profound and selective lymphopaenia in primary lymphatic anomaly patients demonstrates the significance of lymphatic-lymphocyte interactions
Pearce J, Hadcocks L, Mansour S, van Zanten M, Jeffery S, Gordon K, Ostergaard P, Mortimer P, Macallan DC |
Frontiers in immunology | 2023 |
|
Interruption of Lymph Flow Worsens the Skin Inflammation Caused by Saprophytic Staphylococcus epidermidis
Cąkała-Jakimowicz M, Domaszewska-Szostek A, Puzianowska-Kuznicka M |
Biomedicines | 2023 |
|
Novel Interventional Radiology for the Treatment of Various Lymphatic Leakages: Lymphatic Intervention and Embolization
Hur S |
Vascular Specialist International | 2023 |
|
Demystifying vascularized lymph node transfers and lymphatico-venous anastomoses
Almadani Y, Davison P, Efanov JI, Kokosis G, Vorstenbosch J |
Annals of translational medicine | 2023 |
|
In vivo lymph node CEST-Dixon MRI in breast cancer patients with metastatic lymph node involvement.
Donahue MJ, Donahue PMC, Jones RS, Garza M, Lee C, Patel NJ, Cooper A, De Vis JB, Meszoely I, Crescenzi R |
Magnetic resonance in medicine | 2023 |
|
Exploring disease interrelationships in patients with lymphatic disorders: A single center retrospective experience
S Rockson, X Zhou, L Zhao, D Hosseini, X Jiang, A Sweatt, D Kim, W Tian, M Snyder, M Nicolls |
Clinical and Translational Medicine | 2022 |
|
The bright future of nanotechnology in lymphatic system imaging and imaging-guided surgery
S Qi, X Wang, K Chang, W Shen, G Yu, J Du |
Journal of nanobiotechnology | 2022 |
|
The American Venous Forum, American Vein and Lymphatic Society and the Society for Vascular Medicine expert opinion consensus on lymphedema diagnosis and treatment
F Lurie, R Malgor, T Carman, S Dean, M Iafrati, N Khilnani, N Labropoulos, T Maldonado, P Mortimer, T O'Donnell, J Raffetto, S Rockson, A Gasparis |
Phlebology / Venous Forum of the Royal Society of Medicine | 2022 |
|
Current Mechanistic Understandings of Lymphedema and Lipedema: Tales of Fluid, Fat, and Fibrosis
Duhon BH, Phan TT, Taylor SL, Crescenzi RL, Rutkowski JM |
International journal of molecular sciences | 2022 |
|
Lymph Leakage Promotes Immunosuppression by Enhancing Anti-Inflammatory Macrophage Polarization
Herrada AA, Olate-Briones A, Lazo-Amador R, Liu C, Hernández-Rojas B, Riadi G, Escobedo N |
Frontiers in immunology | 2022 |
|
Towards Understanding the Lymph Node Response to Skin Infection with Saprophytic Staphylococcus epidermidis
Cąkała-Jakimowicz M, Puzianowska-Kuznicka M |
Biomedicines | 2022 |
|
Nanomaterial-Based Drug Delivery System Targeting Lymph Nodes
Cheng Z, Que H, Chen L, Sun Q, Wei X |
Pharmaceutics | 2022 |
|
Treatment of Recurrent Severe Cellulitis with a Pill in Pocket Approach.
Doub JB |
Infection & Chemotherapy | 2022 |
|
Lymphatics in Cardiovascular Physiology.
Balasubbramanian D, Mitchell BM |
Cold Spring Harbor Perspectives in Medicine | 2022 |
|
Visual analysis of global research output of lymphedema based on bibliometrics
Zhang YD, Zhang X, Wang XY, Han DM, Du JS |
Frontiers in Oncology | 2022 |
|
The interstitial compartment as a therapeutic target in heart failure
Aronson D |
Frontiers in Cardiovascular Medicine | 2022 |
|
Breast Cancer Treatment Decreases Serum Levels of TGF-β1, VEGFR2, and TIMP-2 Compared to Healthy Volunteers: Significance for Therapeutic Outcomes?
Krasnikova V, Pospelova M, Fionik O, Alekseeva T, Samochernykh K, Ivanova N, Trofimov N, Vavilova T, Vasilieva E, Makhanova A, Tonyan S, Nikolaeva A, Kayumova E, Shevtsov M |
Pathophysiology | 2022 |
|
Investigation of clinical characteristics and genome associations in the ‘UK Lipoedema’ cohort
Grigoriadis D, Sackey E, Riches K, van Zanten M, Brice G, England R, Mills M, Dobbins SE, Lee LL, Jeffery S, Dong L, Savage DB, Mortimer PS, Keeley V, Pittman A, Gordon K, Ostergaard P |
PloS one | 2022 |
|
The Lymphatic System, Lymphoedema, and Medical Curricula-Survey of Australian Medical Graduates.
Kruger N, Plinsinga ML, Noble-Jones R, Piller N, Keeley V, Hayes SC |
Cancers | 2022 |
|
KIF11 As a Potential Pan-Cancer Immunological Biomarker Encompassing the Disease Staging, Prognoses, Tumor Microenvironment, and Therapeutic Responses
Guo X, Zhou L, Wu Y, Li J |
Oxidative medicine and cellular longevity | 2022 |
|
Tetracyclines improve experimental lymphatic filariasis pathology by disrupting interleukin-4 receptor-mediated lymphangiogenesis
Julio Furlong-Silva, Stephen D Cross, Amy E Marriott, Nicolas Pionnier, John Archer, Andrew Steven, Stefan Schulte-Merker, Matthias Mack, Young-Kwon Hong, Mark J Taylor, Joseph D Turner |
Journal of Clinical Investigation | 2021 |
|
Nucleoside-modified VEGFC mRNA induces organ-specific lymphatic growth and reverses experimental lymphedema
D Szőke, G Kovács, É Kemecsei, L Bálint, K Szoták-Ajtay, P Aradi, AS Dinnyés, BL Mui, YK Tam, TD Madden, K Karikó, RP Kataru, MJ Hope, D Weissman, BJ Mehrara, N Pardi, Z Jakus |
Nature Communications | 2021 |
|
Fluid pumping of peristaltic vessel fitted with elastic valves
KT Wolf, JB Dixon, A Alexeev |
Journal of Fluid Mechanics | 2021 |
|
Lymphatic dysfunction in advanced cirrhosis: Contextual perspective and clinical implications
R Kumar, U Anand, RN Priyadarshi |
World journal of hepatology | 2021 |
|
Biology of Lymphedema
B Brix, O Sery, A Onorato, C Ure, A Roessler, N Goswami |
Biology : open access journal | 2021 |
|
New lymphatic cell formation is associated with damaged brain tissue clearance after penetrating traumatic brain injury
FW Meng, JT Yu, JY Chen, PF Yang |
Scientific Reports | 2021 |
|
Sex Hormones in Lymphedema
F Morfoisse, A Zamora, E Marchaud, M Nougue, LH Diallo, F David, E Roussel, E Lacazette, AC Prats, F Tatin, B Garmy-Susini |
Cancers | 2021 |
|
Cellulitis in chronic oedema
PS Mortimer |
British Journal of Dermatology | 2021 |
|
Sigmar1’s Molecular, Cellular, and Biological Functions in Regulating Cellular Pathophysiology
R Aishwarya, CS Abdullah, M Morshed, NS Remex, S Bhuiyan |
Frontiers in physiology | 2021 |
|
Assessing Lymphatic Uptake of Lipids Using Magnetic Resonance Imaging: A Feasibility Study in Healthy Human Volunteers with Potential Application for Tracking Lymph Node Delivery of Drugs and Formulation Excipients
A Jewell, H Williams, CL Hoad, PR Gellert, MB Ashford, J Butler, S Stolnik, D Scurr, MJ Stocks, L Marciani, PA Gowland, P Gershkovich |
Pharmaceutics | 2021 |
|
Stimulation of Synthesis and Lysis of Extracellular Matrix Proteins in Fibrosis Associated with Lymphedema
J de Godoy, M de Fatima Guerreiro Godoy, H de Godoy, D Neto |
Dermatopathology | 2021 |
|
Comparison of avascular lymph node fragment transplantation techniques to optimize lymphangiogenesis in the minipig model
C Hadamitzky, F Bruns, K Gratz, L Schindewolffs, K Roth, M Werner, K Gordon, P Vogt, R Pabst |
European Journal of Plastic Surgery | 2021 |
|
Modelling the coupling of the M-clock and C-clock in lymphatic muscle cells
Hancock EJ, Zawieja SD, Macaskill C, Davis MJ, Bertram CD |
Computers in Biology and Medicine | 2021 |
|
Effects of physical therapy on hyaluronan clearance and volume regulating hormones in lower limb lymphedema patients: A pilot study.
Brix B, Apich G, Rössler A, Walbrodt S, Goswami N |
Science Progress | 2021 |
|
Lymphatic Proliferation Ameliorates Pulmonary Fibrosis after Lung Injury
P Baluk, RP Naikawadi, S Kim, F Rodriguez, D Choi, YK Hong, PJ Wolters, DM McDonald |
The American Journal of Pathology | 2020 |
|
The Impact of Estrogen Receptor in Arterial and Lymphatic Vascular Diseases
C Fontaine, F Morfoisse, F Tatin, A Zamora, R Zahreddine, D Henrion, JF Arnal, F Lenfant, B Garmy-Susini |
International journal of molecular sciences | 2020 |
|
Emerging Roles of Mast Cells in the Regulation of Lymphatic Immuno-Physiology
S Pal, S Nath, CJ Meininger, AA Gashev |
Frontiers in immunology | 2020 |
|
Development and Validation of a Risk Model for Breast Cancer–Related Lymphedema
JY Kwan, P Famiyeh, J Su, W Xu, BY Kwan, JM Jones, E Chang, KW Yip, FF Liu |
2020 | |
|
The physiological and pathological functions of VEGFR3 in cardiac and lymphatic development and related diseases
RM Monaghan, DJ Page, P Ostergaard, BD Keavney |
Cardiovascular Research | 2020 |
|
Lymphatic Flow: A Potential Target in Sepsis-Associated Acute Lung Injury C Wu, H Li, P Zhang, C Tian, J Luo, W Zhang, S Bhandari, S Jin, Y Hao |
Journal of inflammation research | 2020 |
|
Update and audit of the St George’s classification algorithm of primary lymphatic anomalies: a clinical and molecular approach to diagnosis
K Gordon, R Varney, V Keeley, K Riches, S Jeffery, MV Zanten, P Mortimer, P Ostergaard, S Mansour |
Journal of medical genetics | 2020 |
|
Short-term molecular and cellular effects of ischemia/reperfusion on vascularized lymph node flaps in rats
FS Frueh, B Jelvani, C Scheuer, C Körbel, BS Kim, P Giovanoli, N Lindenblatt, Y Harder, E Ampofo, MD Menger, MW Laschke, Z Cai |
PloS one | 2020 |
|
Reduced Lymphatic Reserve in Heart Failure With Preserved Ejection Fraction
G Rossitto, S Mary, C McAllister, KB Neves, L Haddow, JP Rocchiccioli, NN Lang, CL Murphy, RM Touyz, MC Petrie, C Delles |
Journal of the American College of Cardiology | 2020 |
|
Bioimpedance Analysis for Predicting Outcomes of Complex Decongestive Therapy for Gynecological Cancer Related Lymphedema: A Feasibility Study
SH Bae, WJ Kim, YJ Seo, JY Kim, JY Jeon |
Annals of Rehabilitation Medicine | 2020 |
|
Examining Obesity in Lymphedema: A Retrospective Study of 178 New Patients with Suspected Lymphedema at a Canadian Hospital-Based Clinic
SM Shallwani, P Hodgson, A Towers |
Physiotherapy Canada | 2020 |
|
Diagnostic approach to lower limb edema
AP Gasparis, PS Kim, SM Dean, NM Khilnani, N Labropoulos |
Phlebology / Venous Forum of the Royal Society of Medicine | 2020 |
|
Uso de software na imagem ultrassonográfica para diferenciação de edema de origem venosa e de origem linfática em membros inferiores
VL de Carvalho, GB Pitta, SX Cunha |
Jornal Vascular Brasileiro | 2020 |
|
K ATP Channel Openers Inhibit Lymphatic Contractions and Lymph Flow as a Possible Mechanism of Peripheral Edema
BR Garner, AJ Stolarz, D Stuckey, M Sarimollaoglu, Y Liu, PT Palade, NJ Rusch, S Mu |
The Journal of pharmacology and experimental therapeutics | 2020 |
|
Lymphatic Anatomy and Physiology
AK Goswami, MS Khaja, T Downing, N Kokabi, WE Saad, BS Majdalany |
Seminars in interventional radiology | 2020 |
|
A 61-year-old woman with chronic leg lymphedema managed with complete decongestive therapy
L Bondalevich, S de Laplante |
CMAJ : Canadian Medical Association Journal | 2020 |
|
Kir6.1‐dependent K ATP channels in lymphatic smooth muscle and vessel dysfunction in mice with Kir6.1 gain‐of‐function
MJ Davis, HJ Kim, SD Zawieja, JA CastorenaGonzalez, P Gui, M Li, BT Saunders, BH Zinselmeyer, GJ Randolph, MS Remedi, CG Nichols |
The Journal of Physiology | 2020 |
|
Application of microscale culture technologies for studying lymphatic vessel biology
CW Chang, AJ Seibel, JW Song |
Microcirculation (New York, N.Y. : 1994) | 2019 |
|
A novel mouse tail lymphedema model for observing lymphatic pump failure during lymphedema development
MJ Weiler, MT Cribb, Z Nepiyushchikh, TS Nelson, JB Dixon |
Scientific Reports | 2019 |
|
Fibrosis and secondary lymphedema: chicken or egg?
RP Kataru, I Wiser, JE Baik, HJ Park, S Rehal, JY Shin, BJ Mehrara |
Translational research : the journal of laboratory and clinical medicine | 2019 |
|
Lymphatic Function and Dysfunction in the Context of Sex Differences
CE Trincot, KM Caron |
2019 | |
|
Lymphatic vasculature in tumor metastasis and immunobiology
X Jiang |
Journal of Zhejiang University SCIENCE B | 2019 |
|
Modulation of Immunity by Lymphatic Dysfunction in Lymphedema
Y Yuan, V Arcucci, SM Levy, MG Achen |
Frontiers in immunology | 2019 |
|
Classification of Widely and Rarely Expressed Genes with Recurrent Neural Network
L Chen, XY Pan, YH Zhang, M Liu, T Huang, YD Cai |
Computational and Structural Biotechnology Journal | 2019 |
|
Comparison of Staging Systems to Assess Lymphedema Caused by Cancer Therapies, Lymphatic Filariasis, and Podoconiosis
J Douglass, L Kelly-Hope |
Lymphatic Research and Biology | 2019 |
|
Hormone therapy outcome in lymphedema
B Garmy-Susini |
Aging | 2019 |
|
Paraxial Mesoderm Is the Major Source of Lymphatic Endothelium
OA Stone, DY Stainier |
Developmental Cell | 2019 |
|
Evidence of functional ryanodine receptors in rat mesenteric collecting lymphatic vessels
M Jo, AN Trujillo, Y Yang, JW Breslin |
American journal of physiology. Heart and circulatory physiology | 2019 |
|
Brain-to-cervical lymph node signaling after stroke
E Esposito, BJ Ahn, J Shi, Y Nakamura, JH Park, ET Mandeville, Z Yu, SJ Chan, R Desai, A Hayakawa, X Ji, EH Lo, K Hayakawa |
Nature Communications | 2019 |
|
Lymphoedema management by independent hospices: a cohort study
A Brown, C Nicholson, A Fearing, J Newton, S Gordon, A Hughes, A Egdell, J Ellam |
BMJ Supportive & Palliative Care | 2019 |
|
Interprofessional Management of Median Arcuate Ligament Syndrome (Dunbar Syndrome) Related to Lumbar Lordosis and Hip Dysplasia: A Patient’s Perspective
SL Janssen, T Scholbach, S Jeno, H Laurie, M Meyer, C Combs |
European journal of case reports in internal medicine | 2019 |
|
Pilot Studies Demonstrate the Potential Benefits of Anti-inflammatory Therapy in Human Lymphedema
Stanley G. Rockson, Wen Tian, Xinguo Jiang, Tatiana Kuznetsova, Francois Haddad, Jamie Zampell, Babak Mehrara, Joshua Sampson, Leslie Roche, Jinah Kim, Mark Nicolls |
JCI Insight | 2018 |
|
Lymphatic System Flows
JE Moore, CD Bertram |
Annual Review of Fluid Mechanics | 2018 |
|
Lymphatic Tissue Engineering and Regeneration
L Alderfer, A Wei, D Hanjaya-Putra |
Journal of biological engineering | 2018 |
|
Physiological Perspective on Therapies of Lymphatic Vessels
WW Kilarski |
Advances in Skin & Wound Care | 2018 |
|
AutoTube: a novel software for the automated morphometric analysis of vascular networks in tissues
JA Montoya-Zegarra, E Russo, P Runge, M Jadhav, AH Willrodt, S Stoma, SF Nørrelykke, M Detmar, C Halin |
Angiogenesis | 2018 |
|
Lymphatic dysfunction in critical illness:
E Burke, SA Datar |
Current Opinion in Pediatrics | 2018 |
|
3.0 T relaxation time measurements of human lymph nodes in adults with and without lymphatic insufficiency: Implications for magnetic resonance lymphatic imaging
R Crescenzi, PM Donahue, VG Braxton, AO Scott, HB Mahany, SK Lants, MJ Donahue |
NMR in Biomedicine | 2018 |
|
Effect of cryopreservation on lymph node fragment regeneration after autologous transplantation in the minipig model
C Hadamitzky, H Perić, SJ Theobald, KF Gratz, H Spohr, R Pabst, PM Vogt |
Innovative Surgical Sciences | 2018 |
|
Methicillin-resistant Staphylococcus aureus causes sustained collecting lymphatic vessel dysfunction
D Jones, EF Meijer, C Blatter, S Liao, ER Pereira, EM Bouta, K Jung, SM Chin, P Huang, LL Munn, BJ Vakoc, M Otto, TP Padera |
Science Translational Medicine | 2018 |
|
Pathway networks generated from human disease phenome
AG Cirincione, KL Clark, MG Kann |
BMC Medical Genomics | 2018 |
|
VIPAR, a quantitative approach to 3D-histopathology applied to lymphatic malformations
René Hägerling, Dominik Drees, Aaron Scherzinger, Cathrin Dierkes, Silvia Martin-Almedina, Stefan Butz, Kristiana Gordon, Michael A. Schafers, Klaus Hinrichs, Pia Ostergaard, Dietmar Vestweber, Tobias Goerge, Sahar Mansour, Xiaoyi Jiang, Peter Mortimer, Friedemann Kiefer |
JCI Insight | 2017 |
|
Organ-specific lymphatic vasculature: From development to pathophysiology
TV Petrova, GY Koh |
Journal of Experimental Medicine | 2017 |
|
Lymphedema evaluation using noninvasive 3T MR lymphangiography: Noninvasive MR Lymphangiography
R Crescenzi, PM Donahue, KG Hartley, AA Desai, AO Scott, V Braxton, H Mahany, SK Lants, MJ Donahue |
Journal of Magnetic Resonance Imaging | 2017 |
|
Effect of pneumatic compression therapy on lymph movement in lymphedema-affected extremities, as assessed by near-infrared fluorescence lymphatic imaging
MB Aldrich, D Gross, JR Morrow, CE Fife, JC Rasmussen |
Journal of Innovative Optical Health Sciences | 2017 |
|
A comprehensive overview on the surgical management of secondary lymphedema of the upper and lower extremities related to prior oncologic therapies
R Garza, R Skoracki, K Hock, SP Povoski |
BMC Cancer | 2017 |
|
Magnetic Resonance Imaging–Based Assessment of Breast Cancer–Related Lymphoedema Tissue Composition:
M Borri, KD Gordon, JC Hughes, ED Scurr, DM Koh, MO Leach, PS Mortimer, MA Schmidt |
Investigative Radiology | 2017 |
|
Simultaneous measurements of lymphatic vessel contraction, flow and valve dynamics in multiple lymphangions using optical coherence tomography
C Blatter, EF Meijer, TP Padera, BJ Vakoc |
Journal of Biophotonics | 2017 |
|
Modulation of mesenteric collecting lymphatic contractions by σ 1 -receptor activation and nitric oxide production
AN Trujillo, C Katnik, J Cuevas, BJ Cha, TE Taylor-Clark, JW Breslin |
American journal of physiology. Heart and circulatory physiology | 2017 |
|
Restoration of lymphatic function rescues obesity in Prox1 haploinsufficient mice
Noelia Escobedo, Steven T. Proulx, Sinem Karaman, Miriam Dillard, Nicole Johnson, Michael Detmar, Guillermo Oliver |
JCI Insight | 2016 |
|
Diphtheria toxin-mediated ablation of lymphatic endothelial cells results in progressive lymphedema
Jason Gardenier, Geoffrey Hespe, Raghu Kataru, Ira Savetsky, Jeremy Torrisi, Gabriela Garcia Nores, Joseph Dayan, David Chang, Jamie Zampell, Ines Martinez-Corral, Segrario Ortega, Babak Mehrara |
JCI Insight | 2016 |
|
Lymphatic Dysfunction, Leukotrienes, and Lymphedema
X Jiang, MR Nicolls, W Tian, SG Rockson |
Annual Review of Physiology | 2016 |
|
Bisphosphonate therapy for osteogenesis imperfecta
K Dwan, CA Phillipi, RD Steiner, D Basel |
Cochrane Database of Systematic Reviews | 2016 |
|
The Lymphatic System in Disease Processes and Cancer Progression
TP Padera, EF Meijer, LL Munn |
Annual Review of Biomedical Engineering | 2016 |
|
Endothelial Mitogen-Activated Protein Kinase Kinase Kinase Kinase 4 Is Critical for Lymphatic Vascular Development and Function
RJ Flach, CA Guo, LV Danai, JC Yawe, S Gujja, YJ Edwards, MP Czech |
Molecular and cellular biology | 2016 |
|
Lymph vessels: the forgotten second circulation in health and disease
LA Adamczyk, K Gordon, I Kholová, LB Meijer-Jorna, N Telinius, PJ Gallagher, AC van der Wal, U Baandrup |
Virchows Archiv | 2016 |
|
Lipidomic Profiling of Adipose Tissue Reveals an Inflammatory Signature in Cancer-Related and Primary Lymphedema
LM Sedger, DL Tull, MJ McConville, DP de Souza, TW Rupasinghe, SJ Williams, S Dayalan, D Lanzer, H Mackie, TC Lam, J Boyages, CM Maya-Monteiro |
PloS one | 2016 |
|
High-resolution 3D volumetry versus conventional measuring techniques for the assessment of experimental lymphedema in the mouse hindlimb
FS Frueh, C Körbel, L Gassert, A Müller, E Gousopoulos, N Lindenblatt, P Giovanoli, MW Laschke, MD Menger |
Scientific Reports | 2016 |
|
A novel mutation in CELSR1 is associated with hereditary lymphedema
ML Gonzalez-Garay, MB Aldrich, JC Rasmussen, R Guilliod, PE Lapinski, PD King, EM Sevick-Muraca |
Vascular cell | 2016 |
|
In vivo label-free measurement of lymph flow velocity and volumetric flow rates using Doppler optical coherence tomography
C Blatter, EF Meijer, AS Nam, D Jones, BE Bouma, TP Padera, BJ Vakoc |
Scientific Reports | 2016 |
|
Aligned nanofibrillar collagen scaffolds – Guiding lymphangiogenesis for treatment of acquired lymphedema
C Hadamitzky, TS Zaitseva, M Bazalova-Carter, MV Paukshto, L Hou, Z Strassberg, J Ferguson, Y Matsuura, R Dash, PC Yang, S Kretchetov, PM Vogt, SG Rockson, JP Cooke, NF Huang |
Biomaterials | 2016 |
|
From sewer to saviour — targeting the lymphatic system to promote drug exposure and activity
NL Trevaskis, LM Kaminskas, CJ Porter |
Nature Reviews Drug Discovery | 2015 |
|
Adrenomedullin in lymphangiogenesis: from development to disease
KR Klein, KM Caron |
Cellular and Molecular Life Sciences | 2015 |
|
Assessment of lymphatic impairment and interstitial protein accumulation in patients with breast cancer treatment-related lymphedema using CEST MRI: CEST MRI and Lymphedema
MJ Donahue, PC Donahue, S Rane, CR Thompson, MK Strother, AO Scott, SA Smith |
Magnetic Resonance in Medicine | 2015 |
|
The lymphatic vasculature revisited
Dontscho Kerjaschki |
Journal of Clinical Investigation | 2014 |
|
Evidence for SH2 Domain-Containing 5′-Inositol Phosphatase-2 (SHIP2) Contributing to a Lymphatic Dysfunction
GD Agollah, ML Gonzalez-Garay, JC Rasmussen, IC Tan, MB Aldrich, C Darne, CE Fife, R Guilliod, EA Maus, PD King, EM Sevick-Muraca, JH Fritz |
PloS one | 2014 |
|
Primary and secondary lymphatic valve development: Molecular, functional and mechanical insights
E Bazigou, JT Wilson, JE Moore |
Microvascular Research | 2014 |
|
Bridging the divide between pathogenesis and detection in lymphedema
JB Dixon, MJ Weiler |
Seminars in Cell & Developmental Biology | 2014 |
|
The Position- and Lymphatic Lumen-Controlled Tissue Chambers to Study Live Lymphatic Vessels and Surrounding Tissues ex Vivo
D Maejima, T Nagai, EA Bridenbaugh, WE Cromer, AA Gashev |
Lymphatic Research and Biology | 2014 |
|
Recent progress in the treatment and prevention of cancer-related lymphedema: Lymphedema Treatment and Prevention
SF Shaitelman, KD Cromwell, JC Rasmussen, NL Stout, JM Armer, BB Lasinski, JN Cormier |
CA A Cancer Journal for Clinicians | 2014 |
|
Comprehensive Physiology
R Terjung |
Comprehensive Physiology | 2010 |
Copyright © 2025 American Society for Clinical Investigation
ISSN: 0021-9738 (print), 1558-8238 (online)