Go to JCI Insight
  • About
  • Editors
  • Consulting Editors
  • For authors
  • Publication ethics
  • Publication alerts by email
  • Advertising
  • Job board
  • Contact
  • Clinical Research and Public Health
  • Current issue
  • Past issues
  • By specialty
    • COVID-19
    • Cardiology
    • Gastroenterology
    • Immunology
    • Metabolism
    • Nephrology
    • Neuroscience
    • Oncology
    • Pulmonology
    • Vascular biology
    • All ...
  • Videos
    • Conversations with Giants in Medicine
    • Video Abstracts
  • Reviews
    • View all reviews ...
    • Pancreatic Cancer (Jul 2025)
    • Complement Biology and Therapeutics (May 2025)
    • Evolving insights into MASLD and MASH pathogenesis and treatment (Apr 2025)
    • Microbiome in Health and Disease (Feb 2025)
    • Substance Use Disorders (Oct 2024)
    • Clonal Hematopoiesis (Oct 2024)
    • Sex Differences in Medicine (Sep 2024)
    • View all review series ...
  • Viewpoint
  • Collections
    • In-Press Preview
    • Clinical Research and Public Health
    • Research Letters
    • Letters to the Editor
    • Editorials
    • Commentaries
    • Editor's notes
    • Reviews
    • Viewpoints
    • 100th anniversary
    • Top read articles

  • Current issue
  • Past issues
  • Specialties
  • Reviews
  • Review series
  • Conversations with Giants in Medicine
  • Video Abstracts
  • In-Press Preview
  • Clinical Research and Public Health
  • Research Letters
  • Letters to the Editor
  • Editorials
  • Commentaries
  • Editor's notes
  • Reviews
  • Viewpoints
  • 100th anniversary
  • Top read articles
  • About
  • Editors
  • Consulting Editors
  • For authors
  • Publication ethics
  • Publication alerts by email
  • Advertising
  • Job board
  • Contact

Citations to this article

Neutrophil extracellular traps sequester circulating tumor cells and promote metastasis
Jonathan Cools-Lartigue, … , Paul Kubes, Lorenzo Ferri
Jonathan Cools-Lartigue, … , Paul Kubes, Lorenzo Ferri
Published July 1, 2013
Citation Information: J Clin Invest. 2013;123(8):3446-3458. https://doi.org/10.1172/JCI67484.
View: Text | PDF
Research Article Oncology Article has an altmetric score of 51

Neutrophil extracellular traps sequester circulating tumor cells and promote metastasis

  • Text
  • PDF
Abstract

The majority of patients with cancer undergo at least one surgical procedure as part of their treatment. Severe postsurgical infection is associated with adverse oncologic outcomes; however, the mechanisms underlying this phenomenon are unclear. Emerging evidence suggests that neutrophils, which function as the first line of defense during infections, facilitate cancer progression. Neutrophil extracellular traps (NETs) are extracellular neutrophil-derived DNA webs released in response to inflammatory cues that trap and kill invading pathogens. The role of NETs in cancer progression is entirely unknown. We report that circulating tumor cells become trapped within NETs in vitro under static and dynamic conditions. In a murine model of infection using cecal ligation and puncture, we demonstrated microvascular NET deposition and consequent trapping of circulating lung carcinoma cells within DNA webs. NET trapping was associated with increased formation of hepatic micrometastases at 48 hours and gross metastatic disease burden at 2 weeks following tumor cell injection. These effects were abrogated by NET inhibition with DNAse or a neutrophil elastase inhibitor. These findings implicate NETs in the process of cancer metastasis in the context of systemic infection and identify NETs as potential therapeutic targets.

Authors

Jonathan Cools-Lartigue, Jonathan Spicer, Braedon McDonald, Stephen Gowing, Simon Chow, Betty Giannias, France Bourdeau, Paul Kubes, Lorenzo Ferri

×

Total citations by year

Year: 2025 2024 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014 2009 Total
Citations: 48 83 84 88 109 89 55 60 40 50 19 18 1 744
Citation information
This citation data is accumulated from CrossRef, which receives citation information from participating publishers, including this journal. Not all publishers participate in CrossRef, so this information is not comprehensive. Additionally, data may not reflect the most current citations to this article, and the data may differ from citation information available from other sources (for example, Google Scholar, Web of Science, and Scopus).

Citations to this article in year 2023 (84)

Title and authors Publication Year
Neutrophil Extracellular Traps Promote Metastases of Colorectal Cancers through Activation of ERK Signaling by Releasing Neutrophil Elastase
Okamoto M, Mizuno R, Kawada K, Itatani Y, Kiyasu Y, Hanada K, Hirata W, Nishikawa Y, Masui H, Sugimoto N, Tamura T, Inamoto S, Sakai Y, Obama K
International journal of molecular sciences 2023
Circulating Histones to Detect and Monitor the Progression of Cancer.
Tsoneva DK, Ivanov MN, Conev NV, Manev R, Stoyanov DS, Vinciguerra M
International journal of molecular sciences 2023
The Association of Inflammatory Markers with Maternal-Neonatal Outcome After Cervical Cerclage
Fang J, Lin Y, Chen Z, Lin Y, Pan M
Journal of inflammation research 2023
Peripheral low-density granulocytes after colorectal cancer surgery in predicting recurrence.
Futoh Y, Kumagai Y, Miyato H, Ozawa H, Kanamaru R, Sadatomo A, Ohnishi Y, Koinuma K, Horie H, Yamaguchi H, Lefor AK, Sata N, Kitayama J
2023
Phosphoinositol 3-kinase-driven NET formation involves different isoforms and signaling partners depending on the stimulus
de Carvalho Oliveira V, Tatsiy O, McDonald PP
Frontiers in immunology 2023
Moonlighting chromatin: when DNA escapes nuclear control
Singh J, Boettcher M, Dölling M, Heuer A, Hohberger B, Leppkes M, Naschberger E, Schapher M, Schauer C, Schoen J, Stürzl M, Vitkov L, Wang H, Zlatar L, Schett GA, Pisetsky DS, Liu ML, Herrmann M, Knopf J
Cell Death and Differentiation 2023
Prognostic value of systemic immune-inflammation index in non-metastatic clear cell renal cell carcinoma with tumor thrombus
Gu Y, Fu Y, Pan X, Zhou Y, Ji C, Zhao T, Miao H, Lv H, Da J, Ge J, Wang L, Qu L, Ge S, Guo H, Zhou W
Frontiers in Oncology 2023
Simvastatin Reduces NETosis to Attenuate Severe Asthma by Inhibiting PAD4 Expression
Chen YR, Xiang XD, Sun F, Xiao BW, Yan MY, Peng B, Liu D
Oxidative medicine and cellular longevity 2023
NK cells are never alone: crosstalk and communication in tumour microenvironments
Zhou Y, Cheng L, Liu L, Li X
Molecular Cancer 2023
Hepatocyte SGK1 activated by hepatic ischemia-reperfusion promotes the recurrence of liver metastasis via IL-6/STAT3
Li X, Wang Z, Jiao C, Zhang Y, Xia N, Yu W, Chen X, Wikana LP, Liu Y, Sun L, Chen M, Xiao Y, Shi Y, Han S, Pu L
Journal of Translational Medicine 2023
Unobvious Neutrophil Extracellular Traps Signification in the Course of Oral Squamous Cell Carcinoma: Current Understanding and Future Perspectives
Garley M
Cancer control : journal of the Moffitt Cancer Center 2023
Endotoxemia and Gastrointestinal Cancers: Insight into the Mechanisms Underlying a Dangerous Relationship
Manilla V, Di Tommaso N, Santopaolo F, Gasbarrini A, Ponziani FR
Microorganisms 2023
Higher aorta dose increased neutrophil‐to‐lymphocyte ratio resulting in poorer outcomes in stage II‐III non‐small cell lung cancer
Li Y, Fan X, Yu Q, Zhai H, Mi J, Lu R, Jiang G, Wu K
Thoracic Cancer 2023
Perioperative oncolytic virotherapy to counteract surgery-induced immunosuppression and improve outcomes in pancreatic ductal adenocarcinoma.
Mansouri S, Daniel L, Amhis N, Leveille M, Boudreau JE, Alkayyal AA, Collin Y, Tai LH
Frontiers in Oncology 2023
Tailoring therapies to counter the divergent immune landscapes of breast cancer
Attalla S, Taifour T, Muller W
Frontiers in Cell and Developmental Biology 2023
Targeting lung cancer brain metastases: a narrative review of emerging insights for anaplastic lymphoma kinase (ALK)-positive disease
Nelson TA, Wang N
Translational Lung Cancer Research 2023
Perioperative lidocaine and dexmedetomidine intravenous infusion reduce the serum levels of NETs and biomarkers of tumor metastasis in lung cancer patients: A prospective, single-center, double-blinded, randomized clinical trial.
Ren B, Cheng M, Liu C, Zheng H, Zhang J, Chen W, Song J, Zhuang J, Liu T, Wang R, Wang Z
Frontiers in Oncology 2023
The Formation of NETs and Their Mechanism of Promoting Tumor Metastasis
Li J, Chen J, Sun J, Li K
Journal of Oncology 2023
Neutrophil extracellular traps in tumor progression and immunotherapy
Yan M, Gu Y, Sun H, Ge Q
Frontiers in immunology 2023
Neutrophil Extracellular Traps and Cancer: Trapping Our Attention with Their Involvement in Ovarian Cancer
Castaño M, Tomás-Pérez S, González-Cantó E, Aghababyan C, Mascarós-Martínez A, Santonja N, Herreros-Pomares A, Oto J, Medina P, Götte M, Mc Cormack BA, Marí-Alexandre J, Gilabert-Estellés J
International journal of molecular sciences 2023
Apoptosis-induced nuclear expulsion in tumor cells drives S100a4-mediated metastatic outgrowth through the RAGE pathway
Park WY, Gray JM, Holewinski RJ, Andresson T, So JY, Carmona-Rivera C, Hollander MC, Yang HH, Lee M, Kaplan MJ, Cappell SD, Yang L
Nature cancer 2023
Immunosuppressive reprogramming of neutrophils by lung mesenchymal cells promotes breast cancer metastasis.
Gong Z, Li Q, Shi J, Li P, Hua L, Shultz LD, Ren G
Science Immunology 2023
Neutrophil-to-lymphocyte ratio is a negative prognostic biomarker for luminal A breast cancer
Xiang Y, Zhang N, Lei H, Wu J, Wang W, Zhang H, Zeng X
Gland Surgery 2023
Baseline neutrophil-to- ratio combined with the change during treatment provides risk stratification for metastatic malignant melanoma patients treated with PD-1 inhibitors in a Chinese population
Wang C, Liu S, Li X, Cui K, Zhang W, Du Y
Frontiers in Oncology 2023
Neutrophil diversity in inflammation and cancer
Carnevale S, Ceglie ID, Grieco G, Rigatelli A, Bonavita E, Jaillon S
Frontiers in immunology 2023
Immune Determinants of the Pre-Metastatic Niche
Patras L, Shaashua L, Matei I, Lyden D
Cancer Cell 2023
The emerging role of neutrophil extracellular traps in cancer: from lab to ward
Zhong W, Wang Q, Shen X, Du J
Frontiers in Oncology 2023
Neutrophil elastase: From mechanisms to therapeutic potential
Zeng W, Song Y, Wang R, He R, Wang T
Journal of Pharmaceutical Analysis 2023
Anti-triple-negative breast cancer metastasis efficacy and molecular mechanism of the STING agonist for innate immune pathway
Lu X, Wang X, Cheng H, Wang X, Liu C, Tan X
Annals of Medicine 2023
Radiation-induced tumor immune microenvironments and potential targets for combination therapy.
Guo S, Yao Y, Tang Y, Xin Z, Wu D, Ni C, Huang J, Wei Q, Zhang T
Signal Transduction and Targeted Therapy 2023
The Interplay between T Cells and Cancer: The Basis of Immunotherapy
Chen C, Liu X, Chang CY, Wang HY, Wang RF
Genes & development 2023
Mapping current status and emerging trends in NETosis: A bibliometric study
Wang H, Liu X, Jia Z, Liu L, Qi Y, Zhou Q, Xu F, Zhang Y
Medicine 2023
CD200R signaling contributes to unfavorable tumor microenvironment through regulating production of chemokines by tumor-associated myeloid cells
Lin CH, Talebian F, Yang L, Zhu J, Liu JQ, Zhao B, Basu S, Pan X, Chen X, Yan P, Carson WE, Xin G, Wen H, Wang R, Li Z, Ma Q, Bai XF
iScience 2023
Current insights into the hepatic microenvironment and advances in immunotherapy for hepatocellular carcinoma
Zhao M, Huang H, He F, Fu X
Frontiers in immunology 2023
Bladder cancer patients have increased NETosis and impaired DNaseI-mediated NET degradation that can be therapeutically restored in vitro
Herranz R, Oto J, Hueso M, Plana E, Cana F, Castaño M, Cordón L, Ramos-Soler D, Bonanad S, Vera-Donoso CD, Martínez-Sarmiento M, Medina P
Frontiers in immunology 2023
Tumor-neutrophil crosstalk promotes in vitro and in vivo glioblastoma progression.
Rubenich DS, de Souza PO, Omizzollo N, Aubin MR, Basso PJ, Silva LM, da Silva EM, Teixeira FC, Gentil GFS, Domagalski JL, Cunha MT, Gadelha KA, Diel LF, Gelsleichter NE, Rubenich AS, Lenz GS, de Abreu AM, Kroeff GM, Paz AH, Visioli F, Lamers ML, Wink MR, Worm PV, Araújo AB, Sévigny J, Câmara NOS, Ludwig N, Braganhol E
Frontiers in immunology 2023
NETworking with cancer: the bidirectional interplay between cancer and neutrophil extracellular traps
Adrover JM, McDowell SA, He XY, Quail DF, Egeblad M
Cancer Cell 2023
ENPP1 Immunobiology as a Therapeutic Target.
Ruiz-Fernández de Córdoba B, Martínez-Monge R, Lecanda F
Clinical cancer research 2023
Molecular Mechanisms of Colorectal Liver Metastases
Tsilimigras DI, Ntanasis-Stathopoulos I, Pawlik TM
Cells 2023
Associations of subcutaneous fat area and Systemic Immune-inflammation Index with survival in patients with advanced gastric cancer receiving dual PD-1 and HER2 blockade
He M, Chen ZF, Zhang L, Gao X, Chong X, Li HS, Shen L, Ji J, Zhang X, Dong B, Li ZY, Lei T
Journal for ImmunoTherapy of Cancer 2023
NLRP3 Exacerbate NETosis-Associated Neuroinflammation in an LPS-Induced Inflamed Brain.
Byun DJ, Lee J, Yu JW, Hyun YM
Immune Network 2023
Deciphering the role of NETosis-related signatures in the prognosis and immunotherapy of soft-tissue sarcoma using machine learning
Qi L, Chen F, Wang L, Yang Z, Zhang W, Li Z
Frontiers in pharmacology 2023
The Predictive Role of Inflammatory Biomarkers for Treatment Response and Progression-Free Survival in Patients with Hepatocellular Carcinoma Receiving Hepatic Arterial Infusion Chemotherapy with FOLFOX Regimen: A Preliminary Study
Zhao Y, Liu J, Xiong Z, Gu S, Xia X
Journal of Hepatocellular Carcinoma 2023
Circulating and Tumor-Associated Neutrophils in the Era of Immune Checkpoint Inhibitors: Dynamics, Phenotypes, Metabolism, and Functions
Gibellini L, Borella R, Santacroce E, Serattini E, Boraldi F, Quaglino D, Aramini B, De Biasi S, Cossarizza A
Cancers 2023
A Novel Hematological Inflammation-Nutrition Score (HINS) and Its Related Nomogram Model to Predict Survival Outcome in Advanced Gastric Cancer Patients Receiving First-Line Palliative Chemotherapy.
Chen C, Wang Z, Qin Y
Journal of inflammation research 2023
Immune Checkpoint Inhibitors, Small-Molecule Immunotherapies and the Emerging Role of Neutrophil Extracellular Traps in Therapeutic Strategies for Head and Neck Cancer
O\u2019Meara CH, Jafri Z, Khachigian LM
International journal of molecular sciences 2023
Prognostic value of neutrophil extracellular trap signature in clear cell renal cell carcinoma
Li R, Jiang X, Wang P, Liu X
Frontiers in Oncology 2023
Tumour extracellular vesicles induce neutrophil extracellular traps to promote lymph node metastasis
Su X, Brassard A, Bartolomucci A, Dhoparee\u2010Doomah I, Qiu Q, Tsering T, Rohanizadeh R, Koufos O, Giannias B, Bourdeau F, Feng L, Messina\u2010Pacheco J, Leo S, Sangwan V, Quail D, Tankel J, Spicer J, Burnier JV, Bailey SD, Ferri L, Cools\u2010Lartigue J
Journal of Extracellular Vesicles 2023
A Novel Neutrophil Extracellular Traps Signature for Overall Survival Prediction and Tumor Microenvironment Identification in Gastric Cancer
Qu Z, Han Y, Zhu Q, Ding W, Wang Y, Zhang Y, Wei W, Lei Y, Li M, Jiao Y, Gu K, Zhang Y
Journal of inflammation research 2023
Neutrophil extracellular traps−related signature predicts the prognosis and immune infiltration in gastric cancer
Li M, Zhao Z, Mak TK, Wang X, Chen J, Ren H, Yu Z, Zhang C
Frontiers in Medicine 2023
Myeloperoxidase Alters Lung Cancer Cell Function to Benefit Their Survival.
Cosic-Mujkanovic N, Valadez-Cosmes P, Maitz K, Lueger A, Mihalic ZN, Runtsch MC, Kienzl M, Davies MJ, Chuang CY, Heinemann A, Schicho R, Marsche G, Kargl J
2023
FGF19‐Induced Inflammatory CAF Promoted Neutrophil Extracellular Trap Formation in the Liver Metastasis of Colorectal Cancer
Li C, Chen T, Liu J, Wang Y, Zhang C, Guo L, Shi D, Zhang T, Wang X, Li J
Advanced Science 2023
TGF-β1 activates neutrophil signaling and gene expression but not migration
Hein LE, SenGupta S, Gunasekaran G, Johnson CN, Parent CA
PloS one 2023
The role of platelets in the regulation of tumor growth and metastasis: the mechanisms and targeted therapy
Liao K, Zhang X, Liu J, Teng F, He Y, Cheng J, Yang Q, Zhang W, Xie Y, Guo D, Cao G, Xu Y, Huang B, Wang X
2023
Neutrophil extracellular traps and neutrophil-related mediators in human thyroid cancer.
Modestino L, Cristinziano L, Poto R, Ventrici A, Trocchia M, Ferrari SM, Fallahi P, Paparo SR, Marone G, Antonelli A, Varricchi G, Galdiero MR
Frontiers in immunology 2023
Exploring the potential use of Chinese herbs in regulating the inflammatory microenvironment of tumours based on the concept of ‘state-target identification and treatment’: a scooping review
Lian J, Lin D, Huang Y, Chen X, Chen L, Zhang F, Tang P, Xie J, Hou X, Du Z, Deng J, Hao E, Liu J
Chinese medicine 2023
Secretomes of M1 and M2 macrophages decrease the release of neutrophil extracellular traps.
Manda-Handzlik A, Cieloch A, Kuźmicka W, Mroczek A, Stelmaszczyk-Emmel A, Demkow U, Wachowska M
Scientific Reports 2023
Chronic stress induces pulmonary epithelial cells to produce acetylcholine that remodels lung pre-metastatic niche of breast cancer by enhancing NETosis
Pan J, Zhang L, Wang X, Li L, Yang C, Wang Z, Su K, Hu X, Zhang Y, Ren G, Jiang J, Li P, Huang J
Journal of experimental & clinical cancer research : CR 2023
Neutrophil peptidylarginine deiminase 4 is essential for detrimental age-related cardiac remodelling and dysfunction in mice
Van Bruggen S, Kraisin S, Van Wauwe J, Bomhals K, Stroobants M, Carai P, Frederix L, Van De Bruaene A, Witsch T, Martinod K
Philosophical Transactions of the Royal Society B: Biological Sciences 2023
Integrated analysis of NET‐DNA receptor CCDC25 in malignant tumors: Pan‐cancer analysis
Cheng X, Yin X, Song J
2023
Inhibition of neutrophil extracellular trap formation alleviates vascular dysfunction in type 1 diabetic mice
Liu C, Yalavarthi S, Tambralli A, Zeng L, Rysenga CE, Alizadeh N, Hudgins L, Liang W, NaveenKumar SK, Shi H, Shelef MA, Atkins KB, Pennathur S, Knight JS
Science Advances 2023
Advances in proteomics: characterization of the innate immune system after birth and during inflammation
Bennike TB
Frontiers in immunology 2023
The role of the tumor microenvironment in endocrine therapy resistance in hormone receptor-positive breast cancer
Yuan J, Yang L, Li Z, Zhang H, Wang Q, Huang J, Wang B, Mohan CD, Sethi G, Wang G
Frontiers in Endocrinology 2023
Prognostic value of systemic inflammation response index in hepatoblastoma patients receiving preoperative neoadjuvant chemotherapy
Zheng C, Ye S, Liu W, Diao M, Li L
Frontiers in Oncology 2023
Lactoferrin and Activated Protein C: Potential Role in Prevention of Cancer Progression and Recurrence
Akhtar N, Wani AK, Jan M, Sinha S, Devkota HP, Li Z, Amin-ul Mannan M, Prakash A
International journal of molecular and cellular medicine 2023
Role of Neutrophil Extracellular Traps in Health and Disease Pathophysiology: Recent Insights and Advances
Islam MM, Takeyama N
International journal of molecular sciences 2023
Targeting NADPH Oxidase and Integrin α5β1 to Inhibit Neutrophil Extracellular Traps-Mediated Metastasis in Colorectal Cancer
Zhu W, Yang S, Meng D, Wang Q, Ji J
International journal of molecular sciences 2023
The implication of neutrophil extracellular traps in nonalcoholic fatty liver disease
Fa P, Ke BG, Dupre A, Tsung A, Zhang H
Frontiers in immunology 2023
Targeting Neutrophil Extracellular Traps: A Novel Antitumor Strategy
Zuo H, Yang M, Ji Q, Fu S, Pu X, Zhang X, Wang X
Journal of Immunology Research 2023
A Vaccine against Cancer: Can There Be a Possible Strategy to Face the Challenge? Possible Targets and Paradoxical Effects
Zefferino R, Conese M
Human vaccines 2023
Exploiting innate immunity for cancer immunotherapy
Yi M, Li T, Niu M, Mei Q, Zhao B, Chu Q, Dai Z, Wu K
Molecular Cancer 2023
Impact of Neutrophil Extracellular Traps Identified by Citrullinated Histone H3 Immunohistochemistry for Postoperative Prognosis in Patients with Extrahepatic Cholangiocarcinomas.
Yamamoto H, Nakanishi Y, Mitsuhashi T, Hatanaka Y, Hatanaka K, Nange A, Yoshida Y, Ino N, Go M, Okamura K, Tsuchikawa T, Nakamura T, Noji T, Asano T, Matsui A, Tanaka K, Murakami S, Ebihara Y, Kurashima Y, Shichinohe T, Hirano S
Annals of Surgical Oncology 2023
ROS regulation in gliomas: implications for treatment strategies
Yang YC, Zhu Y, Sun SJ, Zhao CJ, Bai Y, Wang J, Ma LT
Frontiers in immunology 2023
The Negative Impact of Inflammation-Related Parameters in Prostate Cancer after Robot-Assisted Radical Prostatectomy: A Retrospective Multicenter Cohort Study in Japan (the MSUG94 Group)
Murase K, Kawase M, Ebara S, Tatenuma T, Sasaki T, Ikehata Y, Nakayama A, Toide M, Yoneda T, Sakaguchi K, Teishima J, Makiyama K, Inoue T, Kitamura H, Saito K, Koga F, Urakami S, Koie T
Journal of Clinical Medicine 2023
Exploring the Role of the Gut and Intratumoral Microbiomes in Tumor Progression and Metastasis
Sevcikova A, Mladosievicova B, Mego M, Ciernikova S
International journal of molecular sciences 2023
Beyond the horizon: Neutrophils leading the way in the evolution of immunotherapy.
Rajgopal S, Nakano K, Cook LM
Cancer Medicine 2023
Neutrophil extracellular traps regulating tumorimmunity in hepatocellular carcinoma.
Zhu W, Fan C, Dong S, Li X, Chen H, Zhou W
Frontiers in immunology 2023
Personalised Medicine and the Potential Role of Electrospinning for Targeted Immunotherapeutics in Head and Neck Cancer
O\u2019Meara CH, Nguyen TV, Jafri Z, Boyer M, Shonka DC Jr, Khachigian LM
Nanomaterials 2023
TF/PAR2 Signaling Axis Supports the Protumor Effect of Neutrophil Extracellular Traps (NETs) on Human Breast Cancer Cells
Martins-Cardoso K, Maçao A, Souza JL, Silva AG, König S, Martins-Gonçalves R, Hottz ED, Rondon AM, Versteeg HH, Bozza PT, Almeida VH, Monteiro RQ
Cancers 2023
A novel neutrophil extracellular traps-related lncRNA signature predicts prognosis in patients with early-stage lung adenocarcinoma
Wang H, Shi Y, Xu X, Xu S, Shi Y, Chen W, Wang K
Annals of Medicine 2023
Oral bacterium Streptococcus mutans promotes tumor metastasis through thrombosis formation
Yu L, Hong Y, Maishi N, Matsuda AY, Hida Y, Hasebe A, Kitagawa Y, Hida K
Cancer Science 2023
Vascular regulation of disseminated tumor cells during metastatic spread
Sturgess V, Azubuike UF, Tanner K
2023
Platelet Contributions to the (Pre)metastatic Tumor Microenvironment
Roweth HG
Seminars in thrombosis and hemostasis 2023
Serum Interleukin 6 Level is Associated With Overall Survival and Treatment Response in Gastric and Gastroesophageal Junction Cancer
Karalis JD, Ju MR, Yoon LY, Castro-Dubon EC, Reznik SI, Hammer ST, Porembka MR, Wang SC
Annals of surgery 2023

← Previous 1 2 3 4 Next →

Advertisement

Copyright © 2025 American Society for Clinical Investigation
ISSN: 0021-9738 (print), 1558-8238 (online)

Sign up for email alerts

Picked up by 3 news outlets
Posted by 23 X users
Referenced in 5 patents
On 4 Facebook pages
Referenced in 4 Wikipedia pages
Highlighted by 1 platforms
730 readers on Mendeley
See more details