Citations to this article
Citation Information: J Clin Invest. 2012;122(11):3824-3834. https://doi.org/10.1172/JCI64124.
Abstract
Spinal cord injury (SCI) is a devastating condition producing great personal and societal costs and for which there is no effective treatment. Stem cell transplantation is a promising therapeutic strategy, though much preclinical and clinical research work remains. Here, we briefly describe SCI epidemiology, pathophysiology, and experimental and clinical stem cell strategies. Research in stem cell biology and cell reprogramming is rapidly advancing, with the hope of moving stem cell therapy closer to helping people with SCI. We examine issues important for clinical translation and provide a commentary on recent developments, including termination of the first human embryonic stem cell transplantation trial in human SCI.
Authors
Andrea J. Mothe, Charles H. Tator
Total citations by year
Citations to this article in year 2014 (4)
| Title and authors | Publication | Year |
|---|---|---|
|
Stem cell therapy for central nerve system injuries: glial cells hold the key
L Xiao, C Saiki, R Ide |
NEURAL REGEN RES | 2014 |
|
Electrical stimulation of transplanted motoneurons improves motor unit formation
Y Liu, RM Grumbles, CK Thomas |
Journal of neurophysiology | 2014 |
|
Stem Cell Imaging: From Bench to Bedside
PK Nguyen, J Riegler, JC Wu |
Cell Stem Cell | 2014 |
|
Pilot study: bone marrow stem cells as a treatment for dogs with chronic spinal cord injury
CA Sarmento, MN Rodrigues, RZ Bocabello, AM Mess, MA Miglino |
Regenerative Medicine Research | 2014 |
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