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Andrew S. Greenberg, … , Hideaki Miyoshi, Douglas G. Mashek
Published June 1, 2011
Citation Information: J Clin Invest. 2011;121(6):2102-2110. https://doi.org/10.1172/JCI46069.
Citation Information: J Clin Invest. 2011;121(6):2102-2110. https://doi.org/10.1172/JCI46069.
Abstract
Lipid droplets (LDs) are intracellular organelles that store neutral lipids within cells. Over the last two decades there has been a dramatic growth in our understanding of LD biology and, in parallel, our understanding of the role of LDs in health and disease. In its simplest form, the LD regulates the storage and hydrolysis of neutral lipids, including triacylglycerol and/or cholesterol esters. It is becoming increasingly evident that alterations in the regulation of LD physiology and metabolism influence the risk of developing metabolic diseases such as diabetes. In this review we provide an update on the role of LD-associated proteins and LDs in metabolic disease.
Authors
Andrew S. Greenberg, Rosalind A. Coleman, Fredric B. Kraemer, James L. McManaman, Martin S. Obin, Vishwajeet Puri, Qing-Wu Yan, Hideaki Miyoshi, Douglas G. Mashek
Total citations by year
Citation information
Citations to this article (306)
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N Nitta, T Iino, A Isozaki, M Yamagishi, Y Kitahama, S Sakuma, Y Suzuki, H Tezuka, M Oikawa, F Arai, T Asai, D Deng, H Fukuzawa, M Hase, T Hasunuma, T Hayakawa, K Hiraki, K Hiramatsu, Y Hoshino, M Inaba, Y Inoue, T Ito, M Kajikawa, H Karakawa, Y Kasai, Y Kato, H Kobayashi, C Lei, S Matsusaka, H Mikami, A Nakagawa, K Numata, T Ota, T Sekiya, K Shiba, Y Shirasaki, N Suzuki, S Tanaka, S Ueno, H Watarai, T Yamano, M Yazawa, Y Yonamine, DD Carlo, Y Hosokawa, S Uemura, T Sugimura, Y Ozeki, K Goda |
Nature Communications | 2020 |
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Two Types of Contact Between Lipid Droplets and Mitochondria
L Cui, P Liu |
Frontiers in Cell and Developmental Biology | 2020 |
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Hypoxia, hypoxia-inducible gene 2 (HIG2)/HILPDA, and intracellular lipolysis in cancer
D Povero, SM Johnson, J Liu |
Cancer Letters | 2020 |
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A phosphoprotein helps lipid droplets stay in shape
MJ Spiering |
The Journal of biological chemistry | 2020 |
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Watch What You (Self-) Eat: Autophagic Mechanisms that Modulate Metabolism
V Lahiri, WD Hawkins, DJ Klionsky |
Cell Metabolism | 2019 |
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Fermented Korean Red Ginseng Extract Enriched in Rd and Rg3 Protects against Non-Alcoholic Fatty Liver Disease through Regulation of mTORC1
SY Choi, JS Park, CH Shon, CY Lee, JM Ryu, DJ Son, BY Hwang, HS Yoo, YC Cho, J Lee, JW Kim, YS Roh |
Nutrients | 2019 |
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Perilipin‐2 promotes obesity and progressive fatty liver disease in mice through mechanistically distinct hepatocyte and extra‐hepatocyte actions
DJ Orlicky, AE Libby, ES Bales, RH McMahan, J Monks, FG Rosa, JL McManaman |
The Journal of Physiology | 2019 |
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Skeletal Muscle Lipid Droplets and the Athlete’s Paradox
X Li, Z Li, M Zhao, Y Nie, P Liu, Y Zhu, X Zhang |
Cells | 2019 |
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CIDE Proteins in Human Health and Disease
M Slayton, A Gupta, B Balakrishnan, V Puri |
Cells | 2019 |
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FSP27 and Links to Obesity and Diabetes Mellitus
S Karki |
Current Obesity Reports | 2019 |
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Glycerol kinase 5 confers gefitinib resistance through SREBP1/SCD1 signaling pathway
J Zhou, G Qu, G Zhang, Z Wu, J Liu, D Yang, J Li, M Chang, H Zeng, J Hu, T Fang, Y Song, C Bai |
Journal of Experimental & Clinical Cancer Research | 2019 |
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Neutral Lipid Storage Diseases as Cellular Model to Study Lipid Droplet Function
S Missaglia, R Coleman, A Mordente, D Tavian |
Cells | 2019 |
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Cholesterol and the Safety Factor for Neuromuscular Transmission
I Krivoi, A Petrov |
International journal of molecular sciences | 2019 |
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Metabolomics: Methods and Protocols
SK Bhattacharya |
2019 | |
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Single-molecule localization microscopy and tracking with red-shifted states of conventional BODIPY conjugates in living cells
S Adhikari, J Moscatelli, EM Smith, C Banerjee, EM Puchner |
Nature Communications | 2019 |
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Development of Technetium-99m-Labeled BODIPY-Based Probes Targeting Lipid Droplets Toward the Diagnosis of Hyperlipidemia-Related Diseases
Y Shimizu, K Tanimura, S Iikuni, H Watanabe, H Saji, M Ono |
Molecules (Basel, Switzerland) | 2019 |
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Theracurmin (Highly Bioavailable Curcumin) Prevents High Fat Diet-Induced Hepatic Steatosis Development in Mice
JW Yang, HK Yeo, JH Yun, JU Lee |
Toxicological Research | 2019 |
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Autophagy Attenuation Hampers Progesterone Synthesis during the Development of Pregnant Corpus Luteum
Z Tang, Z Zhang, H Zhang, Y Wang, Y Zhang, J Zhao, H Yang, Z Wang |
Cells | 2019 |
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Electron Tomography Revels that Milk Lipids Originate from Endoplasmic Reticulum Domains with Novel Structural Features
MS Ladinsky, GA Mardones, DJ Orlicky, KE Howell, JL McManaman |
Journal of Mammary Gland Biology and Neoplasia | 2019 |
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Cardiac Snail family of transcription factors directs systemic lipid metabolism in Drosophila
Y Liu, H Bao, W Wang, HY Lim, R Bodmer |
PLoS genetics | 2019 |
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Phenolic Compounds with Antioxidant Properties from Canola Meal Extracts Inhibit Adipogenesis
S Hussain, AU Rehman, DJ Luckett, CL Blanchard, HK Obied, P Strappe |
International journal of molecular sciences | 2019 |
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Lipid Droplets in Cancer: Guardians of Fat in a Stressful World
T Petan, E Jarc, M Jusović |
Molecules (Basel, Switzerland) | 2018 |
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Perilipin-2 deletion promotes carbohydrate-mediated browning of white adipose tissue at ambient temperature
AE Libby, ES Bales, J Monks, DJ Orlicky, JL McManaman |
Journal of lipid research | 2018 |
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Autophagy in Adipose Tissue Physiology and Pathophysiology
M Ferhat, K Funai, S Boudina |
Antioxidants & Redox Signaling | 2018 |
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Rab18 promotes lipid droplet (LD) growth by tethering the ER to LDs through SNARE and NRZ interactions
D Xu, Y Li, L Wu, Y Li, D Zhao, J Yu, T Huang, C Ferguson, RG Parton, H Yang, P Li |
The Journal of Cell Biology | 2018 |
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Polybasic RKKR motif in the linker region of lipid droplet (LD)–associated protein CIDEC inhibits LD fusion activity by interacting with acidic phospholipids
J Wang, C Yan, C Xu, BT Chua, P Li, FJ Chen |
The Journal of biological chemistry | 2018 |
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A Proximity Labeling Strategy Provides Insights into the Composition and Dynamics of Lipid Droplet Proteomes
K Bersuker, CW Peterson, M To, SJ Sahl, V Savikhin, EA Grossman, DK Nomura, JA Olzmann |
Developmental Cell | 2018 |
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Dietary fat-associated osteoarthritic chondrocytes gain resistance to lipotoxicity through PKCK2/STAMP2/FSP27
SW Lee, JH Rho, SY Lee, WT Chung, YJ Oh, JH Kim, SH Yoo, WY Kwon, JY Bae, SY Seo, H Sun, HY Kim, YH Yoo |
Bone Research | 2018 |
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Analysis of hepatic transcriptome demonstrates altered lipid metabolism following Lactobacillus johnsonii BS15 prevention in chickens with subclinical necrotic enteritis
X Qing, D Zeng, H Wang, X Ni, J Lai, L Liu, A Khalique, K Pan, B Jing |
Lipids in Health and Disease | 2018 |
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Inhibition of ghrelin o-acyltransferase attenuated lipotoxicity by inducing autophagy via AMPK–mTOR pathway
S Zhang, YQ Mao, X Fan |
Drug design, development and therapy | 2018 |
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Differential effects of reticulophagy and mitophagy on nonalcoholic fatty liver disease
L Pang, K Liu, D Liu, F Lv, Y Zang, F Xie, J Yin, Y Shi, Y Wang, D Chen |
Cell Death and Disease | 2018 |
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Astragaloside IV Inhibits Adipose Lipolysis and Reduces Hepatic Glucose Production via Akt Dependent PDE3B Expression in HFD-Fed Mice
Q Du, S Zhang, A Li, IS Mohammad, B Liu, Y Li |
Frontiers in physiology | 2018 |
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Lipid metabolism and lipophagy in cancer
M Maan, JM Peters, M Dutta, AD Patterson |
Biochemical and Biophysical Research Communications | 2018 |
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Double Knockout of Peroxiredoxin 4 (Prdx4) and Superoxide Dismutase 1 (Sod1) in Mice Results in Severe Liver Failure
T Homma, T Kurahashi, J Lee, A Nabeshima, S Yamada, J Fujii |
Oxidative medicine and cellular longevity | 2018 |
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Er-Miao-Fang Extracts Inhibits Adipose Lipolysis and Reduces Hepatic Gluconeogenesis via Suppression of Inflammation
W Zhao, X Feng, B Liu, J Xian, N Zhang |
Frontiers in physiology | 2018 |
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Multiplatform Metabolomics Investigation of Antiadipogenic Effects on 3T3-L1 Adipocytes by a Potent Diarylheptanoid
D Du, H Gu, D Djukovic, L Bettcher, M Gong, W Zheng, L Hu, X Zhang, R Zhang, D Wang, D Raftery |
Journal of Proteome Research | 2018 |
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MCAM knockdown impairs PPARγ expression and 3T3-L1 fibroblasts differentiation to adipocytes
M Gabrielli, DG Romero, CN Martini, LJ Iustman, M del C. Vila |
Molecular and Cellular Biochemistry | 2018 |
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Methods for Lipid Droplet Biophysical Characterization in Flaviviridae Infections
AS Martins, IC Martins, NC Santos |
Frontiers in microbiology | 2018 |
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Perilipin 1 Mediates Lipid Metabolism Homeostasis and Inhibits Inflammatory Cytokine Synthesis in Bovine Adipocytes
S Zhang, G Liu, C Xu, L Liu, Q Zhang, Q Xu, H Jia, X Li, X Li |
Frontiers in immunology | 2018 |
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Submucosal fat accumulation in human colorectal tissue and its association with abdominal obesity and insulin resistance
S Wada, Y Yasunaga, K Oka, N Dan, E Tanaka, K Morita, E Masuda, K Yanagawa, H Matsumoto, S Yoshioka, M Tsujie, Y Inui, S Kawata |
United European gastroenterology journal | 2018 |
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The utrophin–beta 2 syntrophin complex regulates adipocyte lipid droplet size independent of adipogenesis
S Krautbauer, M Neumeier, EM Haberl, R Pohl, S Feder, K Eisinger, L Rein-Fischboeck, C Buechler |
Molecular and Cellular Biochemistry | 2018 |
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Co-administration effects of aqueous extract of turnip leaf and metformin in diabetic rats
M Hassanzadeh-Taheri, M Hassanpour-Fard, M Doostabadi, H Moodi, K Vazifeshenas-Darmiyan, M Hosseini |
Journal of traditional and complementary medicine | 2018 |
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The Various Roles of Fatty Acids
C de Carvalho, M Caramujo |
Molecules (Basel, Switzerland) | 2018 |
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Dynamics and functions of lipid droplets
JA Olzmann, P Carvalho |
Nature Reviews Molecular Cell Biology | 2018 |
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Coenzyme Q10 protects against hyperlipidemia-induced cardiac damage in apolipoprotein E-deficient mice
X Zhang, H Liu, Y Hao, L Xu, T Zhang, Y Liu, L Guo, L Zhu, Z Pei |
Lipids in Health and Disease | 2018 |
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Lipid Index Determination by Liquid Fluorescence Recovery in the Fungal Pathogen Ustilago Maydis
L Romero-Aguilar, M Montero-Lomeli, JP Pardo, GG Sánchez |
Journal of visualized experiments : JoVE | 2018 |
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Mammary adipocytes stimulate breast cancer invasion through metabolic remodeling of tumor cells
Yuan Yuan Wang, Attané Camille, Delphine Milhas, Béatrice Dirat, Stéphanie Dauvillier, Adrien Guerard, Julia Gilhodes, Ikrame Lazar, Nathalie Alet, Victor Laurent, Sophie LE GONIDEC, Denis Biard, Caroline Hervé, Frédéric Bost, Guosheng Ren, Françoise Bono, Ghislaine Escourrou, Marc Prentki, Laurence Nieto, Philippe Valet, Catherine MULLER |
JCI Insight | 2017 |
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Ginsenoside Rb2 Alleviates Hepatic Lipid Accumulation by Restoring Autophagy via Induction of Sirt1 and Activation of AMPK
Q Huang, T Wang, L Yang, HY Wang |
International journal of molecular sciences | 2017 |
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Narciclasine attenuates diet-induced obesity by promoting oxidative metabolism in skeletal muscle
SG Julien, SY Kim, R Brunmeir, JR Sinnakannu, X Ge, H Li, W Ma, J Yaligar, BP KN, SS Velan, PV Röder, Q Zhang, CK Sim, J Wu, M Garcia-Miralles, MA Pouladi, W Xie, C McFarlane, W Han, F Xu, H Christofk |
PLoS Biology | 2017 |
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Olfactory receptor 10J5 responding to α-cedrene regulates hepatic steatosis via the cAMP–PKA pathway
T Tong, SE Ryu, Y Min, CA de March, C Bushdid, J Golebiowski, C Moon, T Park |
Scientific Reports | 2017 |
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Lipid Droplet Biogenesis
TC Walther, J Chung, RV Farese |
Annual Review of Cell and Developmental Biology | 2017 |
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Lipid Metabolism and Lipid Droplets in Pancreatic Cancer and Stellate Cells
Y Sunami, A Rebelo, J Kleeff |
Cancers | 2017 |
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Aronia melanocarpa Extract Ameliorates Hepatic Lipid Metabolism through PPARγ2 Downregulation
CH Park, JH Kim, EB Lee, W Hur, OJ Kwon, HJ Park, SK Yoon, W Huang |
PloS one | 2017 |
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Perilipin-2 modulates dietary fat-induced microbial global gene expression profiles in the mouse intestine
X Xiong, ES Bales, D Ir, CE Robertson, JL McManaman, DN Frank, J Parkinson |
Microbiome | 2017 |
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Overexpression of C-type Natriuretic Peptide in Endothelial Cells Protects against Insulin Resistance and Inflammation during Diet-induced Obesity
CR Bae, J Hino, H Hosoda, Y Arai, C Son, H Makino, T Tokudome, T Tomita, T Kimura, T Nojiri, K Hosoda, M Miyazato, K Kangawa |
Scientific Reports | 2017 |
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Breaking fat: The regulation and mechanisms of lipophagy
RJ Schulze, A Sathyanarayan, DG Mashek |
Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids | 2017 |
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Loss of HSulf-1: The Missing Link between Autophagy and Lipid Droplets in Ovarian Cancer
D Roy, S Mondal, A Khurana, DB Jung, R Hoffmann, X He, E Kalogera, T Dierks, E Hammond, K Dredge, V Shridhar |
Scientific Reports | 2017 |
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Mature adipocytes observed to undergo reproliferation and polyploidy
P Xu, J Li, J Liu, J Wang, Z Wu, X Zhang, Y Zhai |
FEBS Open Bio | 2017 |
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ATGL Promotes Autophagy/Lipophagy via SIRT1 to Control Hepatic Lipid Droplet Catabolism
A Sathyanarayan, MT Mashek, DG Mashek |
Cell Reports | 2017 |
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Non-fused Phospholes as Fluorescent Probes for Imaging of Lipid Droplets in Living Cells
KP Nilsson, E Öberg, H Appelqvist |
Frontiers in Chemistry | 2017 |
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Neutral Lipid Storage Diseases: clinical/genetic features and natural history in a large cohort of Italian patients
EM Pennisi, M Arca, E Bertini, C Bruno, D Cassandrini, A Damico, M Garibaldi, F Gragnani, L Maggi, R Massa, S Missaglia, L Morandi, O Musumeci, E Pegoraro, E Rastelli, FM Santorelli, E Tasca, D Tavian, A Toscano, C Angelini |
Orphanet Journal of Rare Diseases | 2017 |
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Establishing the lipid droplet proteome: Mechanisms of lipid droplet protein targeting and degradation
K Bersuker, JA Olzmann |
Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids | 2017 |
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Lipid Droplets in Health and Disease
G Onal, O Kutlu, D Gozuacik, SD Emre |
Lipids in Health and Disease | 2017 |
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Differential proteomics profiling identifies LDPs and biological functions in high-fat diet-induced fatty livers
M Liu, R Ge, W Liu, Q Liu, X Xia, M Lai, L Liang, C Li, L Song, B Zhen, J Qin, C Ding |
Journal of lipid research | 2017 |
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Zebrafish lipid droplets regulate embryonic ATP homeostasis to power early development
A Dutta, DK Sinha |
Open Biology | 2017 |
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Lipid droplet functions beyond energy storage
MA Welte, AP Gould |
Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids | 2017 |
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High-throughput screens using photo-highlighting discover BMP signaling in mitochondrial lipid oxidation
Y Yu, AS Mutlu, H Liu, MC Wang |
Nature Communications | 2017 |
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Non-Targeted Metabolomics Analysis of Golden Retriever Muscular Dystrophy-Affected Muscles Reveals Alterations in Arginine and Proline Metabolism, and Elevations in Glutamic and Oleic Acid In Vivo
M Abdullah, J Kornegay, A Honcoop, T Parry, C Balog-Alvarez, S ONeal, J Bain, M Muehlbauer, C Newgard, C Patterson, M Willis |
Metabolites | 2017 |
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Lipocalin-2 in Fructose-Induced Fatty Liver Disease
J Lambertz, T Berger, TW Mak, J Helden, R Weiskirchen |
Frontiers in physiology | 2017 |
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Identification of seipin-linked factors that act as determinants of a lipid droplet subpopulation
M Eisenberg-Bord, M Mari, U Weill, E Rosenfeld-Gur, O Moldavski, IG Castro, KG Soni, N Harpaz, TP Levine, AH Futerman, F Reggiori, VA Bankaitis, M Schuldiner, M Bohnert |
The Journal of Cell Biology | 2017 |
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The glucose and lipid metabolism reprogramming is gradedependent in clear cell renal cell carcinoma primary cultures and is targetable to modulate cell viability and proliferation
C Bianchi, C Meregalli, S Bombelli, VD Stefano, F Salerno, B Torsello, SD Marco, G Bovo, I Cifola, E Mangano, C Battaglia, G Strada, G Lucarelli, RH Weiss, RA Perego |
Oncotarget | 2017 |
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Tomographic phase microscopy: principles and applications in bioimaging [Invited].
Jin D, Zhou R, Yaqoob Z, So PTC |
Journal of the Optical Society of America. B, Optical physics | 2017 |
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STRUCTURE, FUNCTION AND METABOLISM OF HEPATIC AND ADIPOSE TISSUE LIPID DROPLETS: IMPLICATIONS IN ALCOHOLIC LIVER DISEASE
Natarajan SK, Rasineni K, Ganesan M, Feng D, McVicker BL, McNiven MA, Osna NA, Mott JL, Casey CA, Kharbanda KK |
Current molecular pharmacology | 2017 |
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Acyl CoA synthetase 5 (ACSL5) ablation in mice increases energy expenditure and insulin sensitivity and delays fat absorption
TA Bowman, KR O'Keeffe, T D'Aquila, QW Yan, JD Griffin, EA Killion, DM Salter, DG Mashek, KK Buhman, AS Greenberg |
Molecular Metabolism | 2016 |
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Nimesulide, a cyclooxygenase-2 selective inhibitor, suppresses obesity-related non-alcoholic fatty liver�disease and hepatic insulin resistance through the regulation of�peroxisome proliferator-activated receptor γ
S Tsujimoto, M Kishina, M Koda, Y Yamamoto, K Tanaka, Y Harada, A Yoshida, I Hisatome |
International journal of molecular medicine | 2016 |
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Mice subjected to aP2-Cre mediated ablation of microsomal triglyceride transfer protein are resistant to high fat diet induced obesity
A Bakillah, MM Hussain |
Nutrition & Metabolism | 2016 |
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Communication between natural killer T cells and adipocytes in obesity
M Satoh, K Iwabuchi |
Adipocyte | 2016 |
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The role of expression imbalance between adipose synthesis and storage mediated by PPAR-γ/FSP27 in the formation of insulin resistance in catch up growth
SX Wang, JG Wei, LL Chen, X Hu, W Kong |
Lipids in Health and Disease | 2016 |
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Adipocyte-specific Hypoxia-inducible gene 2 promotes fat deposition and diet-induced insulin resistance
MT DiStefano, RJ Flach, O Senol-Cosar, LV Danai, JV Virbasius, SM Nicoloro, J Straubhaar, S Dagdeviren, M Wabitsch, OT Gupta, JK Kim, MP Czech |
Molecular Metabolism | 2016 |
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Hepatic Notch1 deletion predisposes to diabetes and steatosis via glucose-6-phosphatase and perilipin-5 upregulation
C Bernsmeier, MT Dill, A Provenzano, Z Makowska, I Krol, G Muscogiuri, D Semela, L Tornillo, F Marra, MH Heim, FH Duong |
Laboratory Investigation | 2016 |
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Lipid-laden cells differentially distributed in the aging brain are functionally active and correspond to distinct phenotypes
MK Shimabukuro, LG Langhi, I Cordeiro, JM Brito, CM de Batista, MP Mattson, VM Coelho |
Scientific Reports | 2016 |
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Oncogenic driver genes and the inflammatory microenvironment dictate liver tumor phenotype
MS Matter, JU Marquardt, JB Andersen, C Quintavalle, N Korokhov, JK Stauffer, K Kaji, T Decaens, L Quagliata, F Elloumi, T Hoang, A Molinolo, EA Conner, A Weber, M Heikenwalder, VM Factor, SS Thorgeirsson |
Hepatology | 2016 |
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Regulation of Hepatic Triacylglycerol Metabolism by CGI-58 Does Not Require ATGL Co-activation
CC Lord, D Ferguson, G Thomas, AL Brown, RC Schugar, A Burrows, AD Gromovsky, J Betters, C Neumann, J Sacks, S Marshall, R Watts, M Schweiger, RG Lee, RM Crooke, MJ Graham, JD Lathia, TF Sakaguchi, R Lehner, G Haemmerle, R Zechner, JM Brown |
Cell Reports | 2016 |
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Modeling Nonalcoholic Fatty Liver Disease with Human Pluripotent Stem Cell-Derived Immature Hepatocyte-Like Cells Reveals Activation of PLIN2 and Confirms Regulatory Functions of Peroxisome Proliferator-Activated Receptor Alpha
N Graffmann, S Ring, MA Kawala, W Wruck, A Ncube, HI Trompeter, J Adjaye |
Stem Cells and Development | 2016 |
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SNAREs and cholesterol movement for steroidogenesis
FB Kraemer, WJ Shen, S Azhar |
Molecular and Cellular Endocrinology | 2016 |
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Decoration of intramyocellular lipid droplets with PLIN5 modulates fasting-induced insulin resistance and lipotoxicity in humans
A Gemmink, M Bosma, HJ Kuijpers, J Hoeks, G Schaart, MA van Zandvoort, P Schrauwen, MK Hesselink |
Diabetologia | 2016 |
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Alcohol and fat promote steatohepatitis: a critical role for fat-specific protein 27/CIDEC
S Liangpunsakul, B Gao |
Journal of Investigative Medicine | 2016 |
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Liver-specific loss of Perilipin 2 alleviates diet-induced hepatic steatosis, inflammation, and fibrosis
CP Najt, S Senthivinayagam, MB Aljazi, KA Fader, SD Olenic, JR Brock, TA Lydic, AD Jones, BP Atshaves |
AJP Gastrointestinal and Liver Physiology | 2016 |
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Discovery of plant extracts that greatly delay yeast chronological aging and have different effects on longevity-defining cellular processes
V Lutchman, Y Medkour, E Samson, A Arlia-Ciommo, P Dakik, B Cortes, R Feldman, S Mohtashami, M McAuley, M Chancharoen, B Rukundo, É Simard, VI Titorenko |
Oncotarget | 2016 |
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Omic studies reveal the pathogenic lipid droplet proteins in non-alcoholic fatty liver disease
X Zhang, Y Wang, P Liu |
Protein & Cell | 2016 |
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Three-dimensional label-free imaging and quantification of lipid droplets in live hepatocytes
K Kim, SE Lee, J Yoon, JH Heo, C Choi, YK Park |
Scientific Reports | 2016 |
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Differentiating brown and white adipose tissues by high-resolution diffusion NMR spectroscopy
SK Verma, K Nagashima, J Yaligar, N Michael, SS Lee, T Xianfeng, V Gopalan, SA Sadananthan, R Anantharaj, SS Velan |
Journal of lipid research | 2016 |
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Omega-3 and alpha-tocopherol provide more protection against contaminants in novel feeds for Atlantic salmon ( Salmo salar L.) than omega-6 and gamma tocopherol
L Søfteland, MH Berntssen, JA Kirwan, TR Størseth, MR Viant, BE Torstensen, R Waagbø, PA Olsvik |
Toxicology Reports | 2016 |
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BODIPY 493/503 Staining of Neutral Lipid Droplets for Microscopy and Quantification by Flow Cytometry
B Qiu, M Simon |
Bio-protocol | 2016 |
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Multifactorial resistance to aminopeptidase inhibitor prodrug CHR2863 in myeloid leukemia cells: down-regulation of carboxylesterase 1, drug sequestration in lipid droplets and pro-survival activation ERK/Akt/mTOR.
Verbrugge SE, Al M, Assaraf YG, Kammerer S, Chandrupatla DM, Honeywell R, Musters RP, Giovannetti E, O'Toole T, Scheffer GL, Krige D, de Gruijl TD, Niessen HW, Lems WF, Kramer PA, Scheper RJ, Cloos J, Ossenkoppele GJ, Peters GJ, Jansen G |
Oncotarget | 2016 |
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Perilipin-2 Modulates Lipid Absorption and Microbiome Responses in the Mouse Intestine
DN Frank, ES Bales, J Monks, MJ Jackman, PS MacLean, D Ir, CE Robertson, DJ Orlicky, JL McManaman, F Blachier |
PloS one | 2015 |
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Tubular atrophy in the pathogenesis of chronic kidney disease progression
JR Schelling |
Pediatric Nephrology | 2015 |
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Protective mechanisms of mitochondria and heart function in diabetes
MA Aon, CG Tocchetti, N Bhatt, N Paolocci, S Cortassa |
Antioxidants & Redox Signaling | 2015 |
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Soybean Oil Is More Obesogenic and Diabetogenic than Coconut Oil and Fructose in Mouse: Potential Role for the Liver
P Deol, JR Evans, J Dhahbi, K Chellappa, DS Han, S Spindler, FM Sladek, J Peterson |
PloS one | 2015 |
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How Inflammation Impinges on NAFLD: A Role for Kupffer Cells
N Duarte, IC Coelho, RS Patarrão, JI Almeida, C Penha-Gonçalves, MP Macedo |
BioMed Research International | 2015 |
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Immunoregulation by lipids during the development of non-alcoholic steatohepatitis
Pierluigi Ramadori, Daniela Kroy, Konrad L Streetz |
Hepatobiliary surgery and nutrition | 2015 |
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Lipopolysaccharide binding protein is an adipokine involved in the resilience of the mouse adipocyte to inflammation
JM Moreno-Navarrete, X Escoté, F Ortega, M Camps, W Ricart, A Zorzano, J Vendrell, A Vidal-Puig, JM Fernández-Real |
Diabetologia | 2015 |
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Effects of Intermittent Fasting, Caloric Restriction, and Ramadan Intermittent Fasting on Cognitive Performance at Rest and During Exercise in Adults
A Cherif, B Roelands, R Meeusen, K Chamari |
Sports Medicine | 2015 |
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Effects of chronic sugar consumption on lipid accumulation and autophagy in the skeletal muscle
DD Stefanis, R Mastrocola, D Nigro, P Costelli, M Aragno |
European Journal of Nutrition | 2015 |
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The Lipid Droplet Protein Hypoxia-inducible Gene 2 Promotes Hepatic Triglyceride Deposition by Inhibiting Lipolysis
MT DiStefano, LV Danai, RJ Flach, A Chawla, DJ Pedersen, A Guilherme, MP Czech |
The Journal of biological chemistry | 2015 |
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Turnover of the actomyosin complex in zebrafish embryos directs geometric remodelling and the recruitment of lipid droplets
A Dutta, DK Sinha |
Scientific Reports | 2015 |
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HIF2 -Dependent Lipid Storage Promotes Endoplasmic Reticulum Homeostasis in Clear-Cell Renal Cell Carcinoma
B Qiu, D Ackerman, DJ Sanchez, B Li, JD Ochocki, A Grazioli, E Bobrovnikova-Marjon, JA Diehl, B Keith, MC Simon |
Cancer Discovery | 2015 |
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ATGL-Catalyzed Lipolysis Regulates SIRT1 to Control PGC-1α/PPAR-α Signaling
SA Khan, A Sathyanarayan, MT Mashek, KT Ong, EE Wollaston-Hayden, DG Mashek |
Diabetes | 2015 |
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As the fat flies: the dynamic lipid droplets of Drosophila embryos
MA Welte |
Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids | 2015 |
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Degradation of lipid droplet-associated proteins by chaperone-mediated autophagy facilitates lipolysis
S Kaushik, AM Cuervo |
Nature Cell Biology | 2015 |
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Expanding Roles for Lipid Droplets
MA Welte |
Current Biology | 2015 |
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Autophagy and Lipid Droplets in the Liver
N Martinez-Lopez, R Singh |
Annual Review of Nutrition | 2015 |
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Differential sensing for the regio- and stereoselective identification and quantitation of glycerides
KL Diehl, MA Ivy, S Rabidoux, SM Petry, G Müller, EV Anslyn |
Proceedings of the National Academy of Sciences | 2015 |
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Specialized Cortex Glial Cells Accumulate Lipid Droplets in Drosophila melanogaster
V Kis, B Barti, M Lippai, M Sass, G Roman |
PloS one | 2015 |
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Lipidtropfen-assoziierte Proteine: Bedeutung für Steatose, Steatohepatitis und Hepatokarzinogenese
BK Straub |
Der Pathologe | 2015 |
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Perilipin 4 in human skeletal muscle: localization and effect of physical activity
S Pourteymour, S Lee, TM Langleite, K Eckardt, M Hjorth, C Bindesbøll, KT Dalen, KI Birkeland, CA Drevon, T Holen, F Norheim |
Physiological Reports | 2015 |
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Leptin activation of mTOR pathway in intestinal epithelial cell triggers lipid droplet formation, cytokine production and increased cell proliferation
NP Fazolini, AL Cruz, MB Werneck, JP Viola, CM Maya-Monteiro, PT Bozza |
Cell cycle (Georgetown, Tex.) | 2015 |
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Bringing obesity to light: Rev-erbα, a central player in light-induced adipogenesis in the zebrafish?
R Kopp, N Billecke, J Legradi, M Broeder, SH Parekh, J Legler |
International Journal of Obesity | 2015 |
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The brown adipocyte protein CIDEA promotes lipid droplet fusion via a phosphatidic acid-binding amphipathic helix: ( A ) Live imaging of the LD dynamics during the differentiation of a brown pre-adipocyte, showing the characteristic CIDE-triggered LD enlargement, characterized by the progressive transference of lipids from a donor to an acceptor LD until it is completely absorbed. ( B ) Live imaging of the LD dynamics in an undifferentiated 3T3-L1 cell 6 hr after infection with adenoviral particles carrying the Cidea gene. Red arrows highlight the transient formation of irregularly shaped LD clusters, while yellow arrows mark the fusion of two droplets by transference of lipids. ( C ) CIDEA-v5 expression in Hela cells induces LD enlargement. An enrichment in CIDEA-v5 (red) can be observed in the contact site between two LDs (green). ( D ) Detail of LD fusion by slow transference of lipids in a 3T3-L1 cell stably expressing CIDEA-v5
D Barneda, J Planas-Iglesias, ML Gaspar, D Mohammadyani, S Prasannan, D Dormann, GS Han, SA Jesch, GM Carman, V Kagan, MG Parker, NT Ktistakis, J Klein-Seetharaman, AM Dixon, SA Henry, M Christian |
eLife | 2015 |
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Role of cystathionine beta synthase in lipid metabolism in ovarian cancer.
Chakraborty PK, Xiong X, Mustafi SB, Saha S, Dhanasekaran D, Mandal NA, McMeekin S, Bhattacharya R, Mukherjee P |
Oncotarget | 2015 |
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Lipotoxic disruption of the NHE1-PI(4,5)P2 interaction expedites proximal tubule apoptosis
Shenaz Khan, Bassam Abu Jawdeh, Monu Goel, William Schilling, Mark D. Parker, Michelle Puchowicz, Satya Yadav, Raymond C. Harris, Ashraf El-Meanawy, Malcolm Hoshi, Krekwit Shinlapawittayatorn, Isabelle Deschenes, Eckhard Ficker, Jeffrey R. Schelling |
Journal of Clinical Investigation | 2014 |
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Energy metabolism in the liver
L Rui |
Comprehensive Physiology | 2014 |
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Adipocyte-specific Disruption of Fat-specific Protein 27 Causes Hepatosteatosis and Insulin Resistance in High-fat Diet-fed Mice
N Tanaka, S Takahashi, T Matsubara, C Jiang, W Sakamoto, T Chanturiya, R Teng, O Gavrilova, FJ Gonzalez |
The Journal of biological chemistry | 2014 |
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Mitochondrial and cellular mechanisms for managing lipid excess
MA Aon, N Bhatt, SC Cortassa |
Frontiers in physiology | 2014 |
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Autophagy Facilitates Secretion and Protects against Degeneration of the Harderian Gland
U Koenig, M Fobker, B Lengauer, M Brandstetter, GP Resch, M Gröger, G Plenz, J Pammer, C Barresi, C Hartmann, H Rossiter |
Autophagy | 2014 |
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Pleiotropic Effects of Cavin-1 Deficiency on Lipid Metabolism
SY Ding, MJ Lee, R Summer, L Liu, SK Fried, PF Pilch |
The Journal of biological chemistry | 2014 |
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Modes-of-Action Related to Repeated Dose Toxicity: Tissue-Specific Biological Roles of PPARγ Ligand-Dependent Dysregulation in Nonalcoholic Fatty Liver Disease
MA Sharif, P Alov, V Vitcheva, I Pajeva, I Tsakovska |
PPAR Research | 2014 |
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Adipose Tissue CIDEA Is Associated, Independently of Weight Variation, to Change in Insulin Resistance during a Longitudinal Weight Control Dietary Program in Obese Individuals
E Montastier, S Déjean, CL Gall, WH Saris, D Langin, N Viguerie |
PloS one | 2014 |
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PLIN5 deletion remodels intracellular lipid composition and causes insulin resistance in muscle
RR Mason, R Mokhtar, M Matzaris, A Selathurai, GM Kowalski, N Mokbel, PJ Meikle, CR Bruce, MJ Watt |
Molecular Metabolism | 2014 |
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In Vivo Metabolic Fingerprinting of Neutral Lipids with Hyperspectral Stimulated Raman Scattering Microscopy
D Fu, Y Yu, A Folick, E Currie, RV Farese, TH Tsai, XS Xie, MC Wang |
Journal of the American Chemical Society | 2014 |
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Perilipin 5, a lipid droplet protein adapted to mitochondrial energy utilization:
AR Kimmel, C Sztalryd |
Current Opinion in Lipidology | 2014 |
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An ER Protein Functionally Couples Neutral Lipid Metabolism on Lipid Droplets to Membrane Lipid Synthesis in the ER
DF Markgraf, RW Klemm, M Junker, HK Hannibal-Bach, CS Ejsing, TA Rapoport |
Cell Reports | 2014 |
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Lipid droplet biogenesis
F Wilfling, JT Haas, TC Walther, RV Farese |
Current Opinion in Cell Biology | 2014 |
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Fatty Acids from Membrane Lipids Become Incorporated into Lipid Bodies during Myxococcus xanthus Differentiation
S Bhat, TO Boynton, D Pham, LJ Shimkets |
PloS one | 2014 |
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On the formation of lipid droplets in human adipocytes: the organization of the perilipin-vimentin cortex
H Heid, S Rickelt, R Zimbelmann, S Winter, H Schumacher, Y Dörflinger, C Kuhn, WW Franke |
PloS one | 2014 |
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Lysosome: regulator of lipid degradation pathways
C Settembre, A Ballabio |
Trends in Cell Biology | 2014 |
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Triglycerides in the human kidney cortex: relationship with body size
IA Bobulescu, Y Lotan, J Zhang, TR Rosenthal, JT Rogers, B Adams-Huet, K Sakhaee, OW Moe |
PloS one | 2014 |
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Assessment of lipidomic species in hepatocyte lipid droplets from stressed mouse models
J Hartler, HC Köfeler, M Trötzmüller, GG Thallinger, F Spener |
Scientific Data | 2014 |
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Perilipin 5 Regulates Islet Lipid Metabolism and Insulin Secretion in a cAMP-Dependent Manner: Implication of Its Role in the Postprandial Insulin Secretion
MB Trevino, Y Machida, DR Hallinger, E Garcia, A Christensen, S Dutta, DA Peake, Y Ikeda, Y Imai |
Diabetes | 2014 |
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New concepts in white adipose tissue physiology
Proença AR, Sertié RA, Oliveira AC, Campaãa AB, Caminhotto RO, Chimin P, Lima FB |
Brazilian Journal of Medical and Biological Research | 2014 |
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Functional cardiac lipolysis in mice critically depends on comparative gene identification-58
KA Zierler, D Jaeger, NM Pollak, S Eder, GN Rechberger, FP Radner, G Woelkart, D Kolb, A Schmidt, M Kumari, K Preiss-Landl, B Pieske, B Mayer, R Zimmermann, A Lass, R Zechner, G Haemmerle |
The Journal of biological chemistry | 2013 |
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RhoA mediates defective stem cell function and heterotopic ossification in dystrophic muscle of mice
X Mu, A Usas, Y Tang, A Lu, B Wang, K Weiss, J Huard |
The FASEB Journal | 2013 |
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Uric acid secretion from adipose tissue and its increase in obesity
Y Tsushima, H Nishizawa, Y Tochino, H Nakatsuji, R Sekimoto, H Nagao, T Shirakura, K Kato, K Imaizumi, H Takahashi, M Tamura, N Maeda, T Funahashi, I Shimomura |
The Journal of biological chemistry | 2013 |
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Eicosanoids in metabolic syndrome
JP Hardwick, K Eckman, YK Lee, MA Abdelmegeed, A Esterle, WM Chilian, JY Chiang, BJ Song |
Advances in pharmacology (San Diego, Calif.) | 2013 |
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Balancing the fat: lipid droplets and human disease
N Krahmer, RV Farese, TC Walther |
EMBO Molecular Medicine | 2013 |
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Diets Containing Sea Cucumber (Isostichopus badionotus) Meals Are Hypocholesterolemic in Young Rats
L Olivera-Castillo, A Davalos, G Grant, N Valadez-Gonzalez, J Montero, HA Barrera-Perez, Y Chim-Chi, MA Olvera-Novoa, V Ceja-Moreno, P Acereto-Escoffie, J Rubio-Piña, R Rodriguez-Canul, JM Lobaccaro |
PloS one | 2013 |
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Dental infection of Porphyromonas gingivalis exacerbates high fat diet-induced steatohepatitis in mice
H Furusho, M Miyauchi, H Hyogo, T Inubushi, M Ao, K Ouhara, J Hisatune, H Kurihara, M Sugai, CN Hayes, T Nakahara, H Aikata, S Takahashi, K Chayama, T Takata |
Journal of Gastroenterology | 2013 |
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Retinoic acid-related orphan receptors α and γ: key regulators of lipid/glucose metabolism, inflammation, and insulin sensitivity
AM Jetten, HS Kang, Y Takeda |
Frontiers in Endocrinology | 2013 |
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Perilipin-2-null mice are protected against diet-induced obesity, adipose inflammation, and fatty liver disease
JL McManaman, ES Bales, DJ Orlicky, M Jackman, PS MacLean, S Cain, AE Crunk, A Mansur, CE Graham, TA Bowman, AS Greenberg |
Journal of lipid research | 2013 |
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Non-invasive monitoring of cell metabolism and lipid production in 3D engineered human adipose tissues using label-free multiphoton microscopy
T Chang, MS Zimmerley, KP Quinn, I Lamarre-Jouenne, DL Kaplan, E Beaurepaire, I Georgakoudi |
Biomaterials | 2013 |
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Role of adipose specific lipid droplet proteins in maintaining whole body energy homeostasis
M Konige, H Wang, C Sztalryd |
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease | 2013 |
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Mitochondrial dysfunction induces formation of lipid droplets as a generalized response to stress
SJ Lee, J Zhang, AM Choi, HP Kim |
Oxidative Medicine & Cellular Longevity | 2013 |
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FSP27 and PLIN1 interaction promotes the formation of large lipid droplets in human adipocytes
TH Grahn, Y Zhang, MJ Lee, AG Sommer, G Mostoslavsky, SK Fried, AS Greenberg, V Puri |
Biochemical and Biophysical Research Communications | 2013 |
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A novel JNK2/SREBP-1c pathway involved in insulin-induced fatty acid synthesis in human adipocytes
M Ito, M Nagasawa, N Omae, M Tsunoda, J Ishiyama, T Ide, Y Akasaka, K Murakami |
Journal of lipid research | 2013 |
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Plin2 inhibits cellular glucose uptake through interactions with SNAP23, a SNARE complex protein
S Senthivinayagam, AL McIntosh, KC Moon, BP Atshaves |
PloS one | 2013 |
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Differential phosphorylation of perilipin 1A at the initiation of lipolysis revealed by novel monoclonal antibodies and high content analysis
PM McDonough, D Maciejewski-Lenoir, SM Hartig, RA Hanna, R Whittaker, A Heisel, JB Nicoll, BM Buehrer, K Christensen, MG Mancini, MA Mancini, DP Edwards, JH Price |
PloS one | 2013 |
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Lipid droplet autophagy in the yeast Saccharomyces cerevisiae
T Zutphen, V Todde, R Boer, M Kreim, HF Hofbauer, H Wolinski, M Veenhuis, IJ van der Klei, SD Kohlwein |
Molecular biology of the cell | 2013 |
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Group X secreted phospholipase A(2) induces lipid droplet formation and prolongs breast cancer cell survival
A Pucer, V Brglez, C Payré, J Pungerčar, G Lambeau, T Petan |
Molecular Cancer | 2013 |
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The autophagic inhibitor 3-methyladenine potently stimulates PKA-dependent lipolysis in adipocytes
BL Heckmann, X Yang, X Zhang, J Liu |
British Journal of Pharmacology | 2013 |
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Cell-to-Cell Heterogeneity in Lipid Droplets Suggests a Mechanism to Reduce Lipotoxicity
A Herms, M Bosch, N Ariotti, BJ Reddy, A Fajardo, A Fernández-Vidal, A Alvarez-Guaita, MA Fernández-Rojo, C Rentero, F Tebar, C Enrich, MI Geli, RG Parton, SP Gross, A Pol |
Current Biology | 2013 |
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Lipins, lipinopathies, and the modulation of cellular lipid storage and signaling
LS Csaki, JR Dwyer, LG Fong, P Tontonoz, SG Young, K Reue |
Progress in Lipid Research | 2013 |
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Studying lipolysis in adipocytes by combining siRNA knockdown and adenovirus-mediated overexpression approaches
X Zhang, BL Heckmann, J Liu |
Methods in cell biology | 2013 |
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Cardiac-specific overexpression of perilipin 5 provokes severe cardiac steatosis via the formation of a lipolytic barrier
NM Pollak, M Schweiger, D Jaeger, D Kolb, M Kumari, R Schreiber, S Kolleritsch, P Markolin, GF Grabner, C Heier, KA Zierler, T Rülicke, R Zimmermann, A Lass, R Zechner, G Haemmerle |
Journal of lipid research | 2013 |
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Effects on transcriptional regulation and lipid droplet characteristics in the liver of female juvenile pigs after early postnatal feed restriction and refeeding are dependent on birth weight
C Nebendahl, R Krüger, S Görs, E Albrecht, K Martens, S Hennig, N Storm, W Höppner, R Pfuhl, BU Metzler-Zebeli, HM Hammon, CC Metges |
PloS one | 2013 |
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Lipocalin 13 regulation of glucose and lipid metabolism in obesity
Y Zhou, L Rui |
Vitamins and hormones | 2013 |
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Dynamic regulation of hepatic lipid droplet properties by diet
AE Crunk, J Monks, A Murakami, M Jackman, PS Maclean, M Ladinsky, ES Bales, S Cain, DJ Orlicky, JL McManaman |
PloS one | 2013 |
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Loss-of-Function Mutations in TBC1D20 Cause Cataracts and Male Infertility in blind sterile Mice and Warburg Micro Syndrome in Humans
RP Liegel, MT Handley, A Ronchetti, S Brown, L Langemeyer, A Linford, B Chang, DJ Morris-Rosendahl, S Carpanini, R Posmyk, V Harthill, E Sheridan, GM Abdel-Salam, PA Terhal, F Faravelli, P Accorsi, L Giordano, L Pinelli, B Hartmann, AD Ebert, FA Barr, IA Aligianis, DJ Sidjanin |
The American Journal of Human Genetics | 2013 |
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Aralia cordata Inhibits Triacylglycerol Biosynthesis in HepG2 Cells
MO Kim, SH Lee, JH Seo, IS Kim, AR Han, DO Moon, S Cho, L Cui, J Kim, HS Lee |
Journal of Medicinal Food | 2013 |
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Lipid droplets characterization in adipocyte differentiated 3T3-L1 cells: size and optical density distribution
V Rizzatti, F Boschi, M Pedrotti, E Zoico, A Sbarbati, M Zamboni |
European Journal of Histochemistry : EJH | 2013 |
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Small GTPase Rab40c associates with lipid droplets and modulates the biogenesis of lipid droplets
R Tan, W Wang, S Wang, Z Wang, L Sun, W He, R Fan, Y Zhou, X Xu, W Hong, T Wang |
PloS one | 2013 |
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Protein correlation profiles identify lipid droplet proteins with high confidence
N Krahmer, M Hilger, N Kory, F Wilfling, G Stoehr, M Mann, RV Farese, TC Walther |
Molecular & cellular proteomics : MCP | 2013 |
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Cell Survival during Complete Nutrient Deprivation Depends on Lipid Droplet-fueled -Oxidation of Fatty Acids
AG Cabodevilla, L Sanchez-Caballero, E Nintou, VG Boiadjieva, F Picatoste, A Gubern, E Claro |
The Journal of biological chemistry | 2013 |
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Analysis of Lipid Droplets in Cardiac Muscle
Wang H, Lei M, Hsia RC, Sztalryd C |
Methods in cell biology | 2013 |
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Adipocyte expression of PU.1 transcription factor causes insulin resistance through upregulation of inflammatory cytokine gene expression and ROS production
L Lin, W Pang, K Chen, F Wang, J Gengler, Y Sun, Q Tong |
American journal of physiology. Endocrinology and metabolism | 2012 |
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A Common Thread Connects Antidiabetic Effects of Multiple Nuclear Receptors
DD Moore |
Cell Metabolism | 2012 |
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Mechanisms of Lipotoxicity in the Cardiovascular System
AR Wende, JD Symons, ED Abel |
Current Hypertension Reports | 2012 |
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Regulation of lipid stores and metabolism by lipophagy
K Liu, MJ Czaja |
Cell Death and Differentiation | 2012 |
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WAT is a functional adipocyte?
C Church, M Horowitz, M Rodeheffer |
Adipocyte | 2012 |
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Proteomics in the characterization of adipose dysfunction in obesity
D Brockman, X Chen |
Adipocyte | 2012 |
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Hepatic Hdac3 promotes gluconeogenesis by repressing lipid synthesis and sequestration
Z Sun, RA Miller, RT Patel, J Chen, R Dhir, H Wang, D Zhang, MJ Graham, TG Unterman, GI Shulman, C Sztalryd, MJ Bennett, RS Ahima, MJ Birnbaum, MA Lazar |
Nature Medicine | 2012 |
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Lipophagy: Connecting Autophagy and Lipid Metabolism
R Singh, AM Cuervo |
International Journal of Cell Biology | 2012 |
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Lipid Droplets and Cellular Lipid Metabolism
TC Walther, RV Farese |
Annual Review of Biochemistry | 2012 |
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Dissociating fatty liver and diabetes
Z Sun, MA Lazar |
Trends in Endocrinology & Metabolism | 2012 |
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Fat-specific protein 27 modulates nuclear factor of activated T cells 5 and the cellular response to stress
M Ueno, WJ Shen, S Patel, AS Greenberg, S Azhar, FB Kraemer |
Journal of lipid research | 2012 |
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Distinct mechanisms regulate ATGL-mediated adipocyte lipolysis by lipid droplet coat proteins
X Yang, BL Heckmann, X Zhang, CM Smas, J Liu |
Molecular Endocrinology | 2012 |
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The size of cytoplasmic lipid droplets varies between tumour cell lines of the nervous system: a 1H NMR spectroscopy study
X Pan, M Wilson, C McConville, TN Arvanitis, RA Kauppinen, AC Peet |
Magma (New York, N.Y.) | 2012 |
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Diet-induced obesity alters the differentiation potential of stem cells isolated from bone marrow, adipose tissue and infrapatellar fat pad: the effects of free fatty acids
CL Wu, BO Diekman, D Jain, F Guilak |
International Journal of Obesity | 2012 |
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Milk lipid secretion: recent biomolecular aspects
JL McManaman |
BioMolecular Concepts | 2012 |
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Lipidome and proteome of lipid droplets from the methylotrophic yeast Pichia pastoris
VA Ivashov, K Grillitsch, H Koefeler, E Leitner, D Baeumlisberger, M Karas, G Daum |
Biochimica et Biophysica Acta | 2012 |
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Effects of perilipin 2 antisense oligonucleotide treatment on hepatic lipid metabolism and gene expression
Y Imai, S Boyle, GM Varela, E Caron, X Yin, R Dhir, R Dhir, MJ Graham, RS Ahima |
Physiological genomics | 2012 |
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Simultaneous activation of p38 and JNK by arachidonic acid stimulates the cytosolic phospholipase A2-dependent synthesis of lipid droplets in human monocytes
C Guijas, G Pérez-Chacón, AM Astudillo, JM Rubio, L Gil-de-Gómez, MA Balboa, J Balsinde |
Journal of lipid research | 2012 |
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Direct interaction of Plin2 with lipids on the surface of lipid droplets: a live cell FRET analysis
AL McIntosh, S Senthivinayagam, KC Moon, S Gupta, JS Lwande, CC Murphy, SM Storey, BP Atshaves |
American journal of physiology. Cell physiology | 2012 |
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A frequent variant in the human bile salt export pump gene ABCB11 is associated with hepatitis C virus infection, but not liver stiffness in a German population
R Müllenbach, SN Weber, M Krawczyk, V Zimmer, C Sarrazin, F Lammert, F Grünhage |
BMC Gastroenterology | 2012 |
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Emerging methodologies to investigate lipid-protein interactions
JL Scott, CA Musselman, E Adu-Gyamfi, TG Kutateladze, RV Stahelin |
Integrative biology : quantitative biosciences from nano to macro | 2012 |
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Digging deeper into obesity
Rexford S. Ahima |
Journal of Clinical Investigation | 2011 |
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Comprehensive Physiology
R Terjung |
Comprehensive Physiology | 2011 |
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Genetic dissection of the functions of the melanocortin-3 receptor, a seven-transmembrane G-protein-coupled receptor, suggests roles for central and peripheral receptors in energy homeostasis
K Begriche, PR Levasseur, J Zhang, J Rossi, D Skorupa, LA Solt, B Young, TP Burris, DL Marks, RL Mynatt, AA Butler |
The Journal of biological chemistry | 2011 |
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FSP27 Promotes Lipid Droplet Clustering and Then Fusion to Regulate Triglyceride Accumulation
S Jambunathan, J Yin, W Khan, Y Tamori, V Puri |
PloS one | 2011 |
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The dynamic roles of intracellular lipid droplets: from archaea to mammals
DJ Murphy |
Protoplasma | 2011 |
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Lipid droplet meets a mitochondrial protein to regulate adipocyte lipolysis
AS Greenberg, FB Kraemer, KG Soni, MP Jedrychowski, QW Yan, CE Graham, TA Bowman, A Mansur |
The EMBO Journal | 2011 |
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Re-patterning of skeletal muscle energy metabolism by fat storage-inducing transmembrane protein 2
DA Miranda, TR Koves, DA Gross, A Chadt, H Al-Hasani, GW Cline, GJ Schwartz, DM Muoio, DL Silver |
The Journal of biological chemistry | 2011 |
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A thematic review series: lipid droplet storage and metabolism: from yeast to man
K Reue |
Journal of lipid research | 2011 |
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Pulmonary surfactant: an immunological perspective
ZC Chroneos, Z Sever-Chroneos, VL Shepherd |
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology | 2009 |
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