Citations to this article

Pregenerative medicine: developmental paradigms in the biology of cardiovascular regeneration
B. Alexander Yi, … , Oliver Wernet, Kenneth R. Chien
B. Alexander Yi, … , Oliver Wernet, Kenneth R. Chien
Published January 4, 2010
Citation Information: J Clin Invest. 2010;120(1):20-28. https://doi.org/10.1172/JCI40820.
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Pregenerative medicine: developmental paradigms in the biology of cardiovascular regeneration

Abstract

The ability to create new functional cardiomyocytes is the holy grail of cardiac regenerative medicine. From studies using model organisms, new insights into the fundamental pathways that drive heart muscle regeneration have begun to arise as well as a growing knowledge of the distinct families of multipotent cardiovascular progenitors that generate diverse lineages during heart development. In this Review, we highlight this intersection of the “pregenerative” biology of heart progenitor cells and heart regeneration and discuss the longer term challenges and opportunities in moving toward a therapeutic goal of regenerative cardiovascular medicine.

Authors

B. Alexander Yi, Oliver Wernet, Kenneth R. Chien

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Year: 2017 2014 2013 2012 2011 2010 2009 Total
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Citations to this article (32)

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