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Citations to this article

DC-based cancer vaccines
Eli Gilboa
Eli Gilboa
Published May 1, 2007
Citation Information: J Clin Invest. 2007;117(5):1195-1203. https://doi.org/10.1172/JCI31205.
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Review Series Article has an altmetric score of 12

DC-based cancer vaccines

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Abstract

Because of the large preexisting antigenic load and immunosuppressive environment within a tumor, inducing therapeutically useful antitumor immunity in cancer patients requires the development of powerful vaccination protocols. An approach gaining increasing popularity in the tumor vaccine field is to immunize cancer patients with their own DCs loaded ex vivo with tumor antigens. The underlying premise of this approach is that the efficiency and control over the vaccination process provided by ex vivo manipulation of the DCs generates an optimally potent APC and a superior method for stimulating antitumor immunity in vivo compared with the more conventional direct vaccination methods, offsetting the added cost and complexity associated with this form of customized cell therapy.

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Eli Gilboa

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Total citations by year

Year: 2024 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 Total
Citations: 8 11 5 5 8 8 16 11 4 12 17 20 20 23 28 28 18 3 245
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Citations to this article (245)

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Beilstein Journal of Organic Chemistry 2014
Classification of current anticancer immunotherapies
Galluzzi L, Vacchelli E, Pedro JM, Buqué A, Senovilla L, Baracco EE, Bloy N, Castoldi F, Abastado JP, Agostinis P, Apte RN, Aranda F, Ayyoub M, Beckhove P, Blay JY, Bracci L, Caignard A, Castelli C, Cavallo F, Celis E, Cerundolo V, Clayton A, Colombo MP, Coussens L, Dhodapkar MV, Eggermont AM, Fearon DT, Fridman WH, Fučíková J, Gabrilovich DI, Galon J, Garg A, Ghiringhelli F, Giaccone G, Gilboa E, Gnjatic S, Hoos A, Hosmalin A, Jäger D, Kalinski P, Kärre K, Kepp O, Kiessling R, Kirkwood JM, Klein E, Knuth A, Lewis CE, Liblau R, Lotze MT, Lugli E, Mach JP, Mattei F, Mavilio D, Melero I, Melief CJ, Mittendorf EA, Moretta L, Odunsi A, Okada H, Palucka AK, Peter ME, Pienta KJ, Porgador A, Prendergast GC, Rabinovich GA, Restifo NP, Rizvi N, Sautès-Fridman C, Schreiber H, Seliger B, Shiku H, Silva-Santos B, Smyth MJ, Speiser DE, Spisek R, Srivastava PK, Talmadge JE, Tartour E, Van Der Burg SH, Van Den Eynde BJ, Vile R, Wagner H, Weber JS, Whiteside TL, Wolchok JD, Zitvogel L, Zou W, Kroemer G
Oncotarget 2014
Relationship of vaccine efficacy to the kinetics of DC and T-cell responses induced by PLG-based cancer vaccines
OA Ali, E Doherty, DJ Mooney, D Emerich
Biomatter 2013
Rhamnogalacturonan II is a Toll-like receptor 4 agonist that inhibits tumor growth by activating dendritic cell-mediated CD8+ T cells
SN Park, KT Noh, YI Jeong, ID Jung, HK Kang, GS Cha, SJ Lee, JK Seo, DH Kang, TH Hwang, EK Lee, B Kwon, YM Park
Experimental & molecular medicine 2013
CpG oligodeoxynucleotide as immune adjuvant enhances photodynamic therapy response in murine metastatic breast cancer
Y Xia, GK Gupta, AP Castano, P Mroz, P Avci, MR Hamblin
Journal of Biophotonics 2013
Inflammatory Cytokines Presented from Polymer Matrices Differentially Generate and Activate DCs In Situ
OA Ali, P Tayalia, D Shvartsman, S Lewin, DJ Mooney
Advanced Functional Materials 2013
Natural killer T cells in advanced melanoma patients treated with tremelimumab
FJ Ibarrondo, OO Yang, T Chodon, E Avramis, Y Lee, H Sazegar, J Jalil, B Chmielowski, RC Koya, I Schmid, J Gomez-Navarro, BD Jamieson, A Ribas, B Comin-Anduix
PloS one 2013
Immune-maximizing (IMAX) therapy for cancer: Combination of dendritic cell vaccine and intensity-modulated radiation
Y Shibamoto, M Okamoto, M Kobayashi, S Ayakawa, H Iwata, C Sugie, Y Mitsuishi, H Takahashi
Molecular and Clinical Oncology 2013
Clinical Implications of Co-Inhibitory Molecule Expression in the Tumor Microenvironment for DC Vaccination: A Game of Stop and Go
A Vasaturo, SD Blasio, DG Peeters, CC de Koning, JM de Vries, CG Figdor, SV Hato
Frontiers in immunology 2013
A novel and simple method for generation of human dendritic cells from unfractionated peripheral blood mononuclear cells within 2 days: its application for induction of HIV-1-reactive CD4(+) T cells in the hu-PBL SCID mice
A Kodama, R Tanaka, M Saito, AA Ansari, Y Tanaka
Frontiers in microbiology 2013
A suppressor of cytokine signaling 1 antagonist enhances antigen-presenting capacity and tumor cell antigen-specific cytotoxic T lymphocyte responses by human monocyte-derived dendritic cells
Y Wang, S Wang, Y Ding, Y Ye, Y Xu, H He, Q Li, Y Mi, C Guo, Z Lin, T Liu, Y Zhang, Y Chen, J Yan
Clinical and vaccine immunology : CVI 2013
Bee Venom Phospholipase A2, a Good "Chauffeur" for Delivering Tumor Antigen to the MHC I and MHC II Peptide-Loading Compartments of the Dendritic Cells: The Case of NY-ESO-1
C Almunia, M Bretaudeau, G Held, A Babon, C Marchetti, FA Castelli, A Ménez, B Maillere, D Gillet
PloS one 2013
The natural killer cell response and tumor debulking are associated with prolonged survival in recurrent glioblastoma patients receiving dendritic cells loaded with autologous tumor lysates
S Pellegatta, M Eoli, S Frigerio, C Antozzi, MG Bruzzone, G Cantini, S Nava, E Anghileri, L Cuppini, V Cuccarini, E Ciusani, M Dossena, B Pollo, R Mantegazza, EA Parati, G Finocchiaro
OncoImmunology 2013
Cytotoxicity of tumor antigen specific human T cells is unimpaired by arginine depletion
M Munder, M Engelhardt, D Knies, S Medenhoff, G Wabnitz, C Luckner-Minden, N Feldmeyer, RH Voss, P Kropf, I Müller, R Conradi, Y Samstag, M Theobald, AD Ho, H Goldschmidt, M Hundemer
PloS one 2013
Recombinant rabies viruses expressing GM-CSF or flagellin are effective vaccines for both intramuscular and oral immunizations
M Zhou, G Zhang, G Ren, CW Gnanadurai, Z Li, Q Chai, Y Yang, CM Leyson, W Wu, M Cui, ZF Fu
PloS one 2013
Recombinant mammaglobin A adenovirus-infected dendritic cells induce mammaglobin A-specific CD8+ cytotoxic T lymphocytes against breast cancer cells in vitro
H Cui, W Zhang, W Hu, K Liu, T Wang, N Ma, X Liu, Y Liu, Y Jiang
PloS one 2013
Trial watch
E Vacchelli, I Vitale, A Eggermont, WH Fridman, J Fučíková, I Cremer, J Galon, E Tartour, L Zitvogel, G Kroemer, L Galluzzi
OncoImmunology 2013
Human Parainfluenza Virus Type 2 Vector Induces Dendritic Cell Maturation Without Viral RNA Replication/Transcription
K Hara, M Fukumura, J Ohtsuka, M Kawano, T Nosaka
Human Gene Therapy 2013
Dendritic cell-based immunotherapy in ovarian cancer
A Coosemans, I Vergote, SW van Gool
OncoImmunology 2013
CD8+ T-cell priming and boosting: more antigen-presenting DC, or more antigen per DC?
N Schaft, V Wellner, C Wohn, G Schuler, J Dörrie
Cancer Immunology, Immunotherapy 2013
Activation of Dendritic Cells by the Novel Toll-Like Receptor 3 Agonist RGC100
K Naumann, R Wehner, A Schwarze, C Petzold, M Schmitz, J Rohayem
Clinical and Developmental Immunology 2013
Immune response, clinical outcome and safety of dendritic cell vaccine in combination with cytokine-induced killer cell therapy in cancer patients
YU CUI, X Yang, W Zhu, J Li, X Wu, Y Pang
Oncology Letters 2013
Trial watch
L Galluzzi, L Senovilla, E Vacchelli, A Eggermont, WH Fridman, J Galon, C Sautès-Fridman, E Tartour, L Zitvogel, G Kroemer
OncoImmunology 2012
Tumor-Associated Antigens for Specific Immunotherapy of Prostate Cancer
A Kiessling, R Wehner, S Füssel, M Bachmann, MP Wirth, M Schmitz
Cancers 2012
PD-1/PD-L1 Blockade Can Enhance HIV-1 Gag-specific T Cell Immunity Elicited by Dendritic Cell-Directed Lentiviral Vaccines
B Dai, L Xiao, PD Bryson, J Fang, P Wang
Molecular Therapy 2012
Dendritic Cells The Tumor Microenvironment and the Challenges for an Effective Antitumor Vaccination
F Benencia, L Sprague, J McGinty, M Pate, M Muccioli
Journal of Biomedicine and Biotechnology 2012
Combined Tbet and IL12 Gene Therapy Elicits and Recruits Superior Antitumor Immunity In Vivo
Y Qu, L Chen, DB Lowe, WJ Storkus, JL Taylor
Molecular Therapy 2012
Identification of novel HLA-A*0201-restricted epitopes from anterior gradient-2 as a tumor-associated antigen against colorectal cancer
HJ Lee, CY Hong, CJ Jin, MH Kim, YK Lee, TN Nguyen-Pham, H Lee, BC Park, IJ Chung, HJ Kim, JJ Lee
Cellular and Molecular Immunology 2012
Off-the-shelf Adenoviral-mediated Immunotherapy via Bicistronic Expression of Tumor Antigen and iMyD88/CD40 Adjuvant
JO Kemnade, M Seethammagari, P Narayanan, JM Levitt, AA McCormick, DM Spencer
Molecular Therapy 2012
HPK1 as a novel target for cancer immunotherapy
S Sawasdikosol, R Zha, B Yang, S Burakoff
Immunologic Research 2012
Interleukin-12p70 Expression by Dendritic Cells of HIV-1-Infected Patients Fails to Stimulate gag-Specific Immune Responses
EV Gulck, N Cools, D Atkinson, L Bracke, K Vereecken, M Vekemans, VF van Tendeloo, ZN Berneman, G Vanham
Clinical and Developmental Immunology 2012
Lactobacillus acidophilus Could Modulate the Immune Response Against Breast Cancer in Murine Model
H Maroof, ZM Hassan, AM Mobarez, MA Mohamadabadi
Journal of Clinical Immunology 2012
Current Protocols in Immunology
S Nair, GE Archer, TF Tedder
Current Protocols in Immunology 2012
Immunoregulatory properties of rapamycin-conditioned monocyte-derived dendritic cells and their role in transplantation
C Macedo, H Turquist, D Metes, AW Thomson
Transplantation Research 2012
An optimized method for manufacturing a clinical scale dendritic cell-based vaccine for the treatment of glioblastoma
S Nava, M Dossena, S Pogliani, S Pellegatta, C Antozzi, F Baggi, C Gellera, B Pollo, EA Parati, G Finocchiaro, S Frigerio
PloS one 2012
Expression of ESE-3 isoforms in immunogenic and tolerogenic human monocyte-derived dendritic cells
F Sprater, AO Hovden, S Appel
PloS one 2012
Vaccines for Pancreatic Cancer
KC Soares, L Zheng, B Edil, EM Jaffee
The Cancer Journal 2012
Methionine enkephalin (MENK) improved the functions of bone marrow-derived dendritic cells (BMDCs) loaded with antigen
W Li, J Meng, X Li, H Hua, Y Meng, Q Wang, E Wang, F Shan
Human Vaccines & Immunotherapeutics 2012
In vivo imaging of lymph node migration of MNP- and (111)In-labeled dendritic cells in a transgenic mouse model of breast cancer (MMTV-Ras).
Martelli C, Borelli M, Ottobrini L, Rainone V, Degrassi A, Russo M, Gianelli U, Bosari S, Fiorini C, Trabattoni D, Clerici M, Lucignani G
Molecular Imaging and Biology 2012
Synergistical toll-like receptors activated dendritic cells induce antitumor effects against carcinoembryonic antigen-expressing colon cancer.
Hong X, Dong T, Hu J, Yi T, Li W, Zhang Z, Lin S, Niu W
International Journal of Colorectal Disease 2012
RAFTsomes containing epitope-MHC-II complexes mediated CD4+ T cell activation and antigen-specific immune responses.
Ding Q, Chen J, Wei X, Sun W, Mai J, Yang Y, Xu Y
Pharmaceutical Research 2012
Metastatic melanoma patients treated with dendritic cell vaccination, Interleukin-2 and metronomic cyclophosphamide: results from a phase II trial
Ellebaek E, Engell-Noerregaard L, Iversen TZ, Froesig TM, Munir S, Hadrup SR, Andersen MH, Svane IM
Cancer Immunology, Immunotherapy 2012
A composite MyD88/CD40 “switch” synergistically activates mouse and human dendritic cells for enhanced anti-tumor efficacy
Priyadharshini Narayanan, Natalia Lapteva, Mamatha Seethammagari, Jonathan Levitt, Kevin Slawin, David Spencer
Journal of Clinical Investigation 2011
Viral tumor inflammation facilitates effective dendritic cell cancer immunotherapy in a regulatory T cell-dependent manner
Norman Woller, Sarah Knocke, Bettina Mundt, Engin Gürlevik, Nina Strüver, Arnold Kloos, Bita Boozari, Peter Schache, Michael P. Manns, Nisar Malek, Tim Sparwasser, Lars Zender, Thomas Wirth, Stefan Kubicka, Florian Kühnel
Journal of Clinical Investigation 2011
Maturation of monocyte derived dendritic cells with OK432 boosts IL-12p70 secretion and conveys strong T-cell responses
AO Hovden, M Karlsen, R Jonsson, HJ Aarstad, S Appel
BMC Immunology 2011
A gynecologic oncology group phase II trial of two p53 peptide vaccine approaches: subcutaneous injection and intravenous pulsed dendritic cells in high recurrence risk ovarian cancer patients
OE Rahma, E Ashtar, M Czystowska, ME Szajnik, E Wieckowski, S Bernstein, VE Herrin, MA Shams, SM Steinberg, M Merino, W Gooding, C Visus, AB DeLeo, JK Wolf, JG Bell, JA Berzofsky, TL Whiteside, SN Khleif
Cancer Immunology, Immunotherapy 2011
Effect of Oxygen Levels on the Physiology of Dendritic Cells: Implications for Adoptive Cell Therapy
D Futalan, CT Huang, IG Schmidt-Wolf, M Larsson, D Messmer
Molecular Medicine 2011
Novel Immunotherapeutic Strategies of Gastric Cancer Treatment
A Amedei, M Benagiano, C Bella, E Niccolai, MM D'Elios
Journal of Biomedicine and Biotechnology 2011
Disruption of the SapM locus in Mycobacterium bovis BCG improves its protective efficacy as a vaccine against M. tuberculosis
N Festjens, P Bogaert, A Batni, E Houthuys, E Plets, D Vanderschaeghe, B Laukens, B Asselbergh, E Parthoens, RD Rycke, MA Willart, P Jacques, D Elewaut, P Brouckaert, BN Lambrecht, K Huygen, N Callewaert
EMBO Molecular Medicine 2011
Immunological and Clinical Effects of Vaccines Targeting p53-Overexpressing Malignancies
R Vermeij, N Leffers, SH van der Burg, CJ Melief, T Daemen, HW Nijman
Journal of Biomedicine and Biotechnology 2011
Cancer-Immune Equilibrium: Questions Unanswered
A Bhatia, Y Kumar
Cancer Microenvironment 2011
Specific microtubule-depolymerizing agents augment efficacy of dendritic cell-based cancer vaccines
CC Wen, HM Chen, SS Chen, LT Huang, WT Chang, WC Wei, LC Chou, P Arulselvan, JB Wu, SC Kuo, NS Yang
Journal of Biomedical Science 2011
Carthamus Tinctorius Enhances the Antitumor Activity of Dendritic Cell Vaccines via Polarization toward Th1 Cytokines and Increase of Cytotoxic T Lymphocytes
JM Chang, LM Hung, YJ Chyan, CM Cheng, RY Wu
Evidence-based complementary and alternative medicine : eCAM 2011
Tolerogenic dendritic cells and their potential applications
J Hu, Y Wan
Immunology 2011
Biomaterial-Based Vaccine Induces Regression of Established Intracranial Glioma in Rats
OA Ali, E Doherty, WJ Bell, T Fradet, J Hudak, MT Laliberte, DJ Mooney, DF Emerich
Pharmaceutical Research 2011
In vivo modulation of dendritic cells by engineered materials: Towards new cancer vaccines
J Kim, DJ Mooney
Nano Today 2011
Engineering Dendritic Cells to Enhance Cancer Immunotherapy
JE Boudreau, A Bonehill, K Thielemans, Y Wan
Molecular Therapy 2011
Generation of immunogenic and tolerogenic clinical-grade dendritic cells
T Kalantari, E Kamali-Sarvestani, B Ciric, MH Karimi, M Kalantari, A Faridar, H Xu, A Rostami
Immunologic Research 2011
Dendritic cell vaccines in cancer immunotherapy: from biology to translational medicine
H Xu, X Cao
Frontiers of Medicine 2011
Poly I: C-activated dendritic cells that were generated in CellGro for use in cancer immunotherapy trials
J Fučíková, D Rožková, H Ulčová, V Budinský, K Sochorová, K Pokorná, J Bartůňková, R Špíšek
Journal of Translational Medicine 2011
CD40-Activated B Cell Cancer Vaccine Improves Second Clinical Remission and Survival in Privately Owned Dogs with Non-Hodgkin's Lymphoma
KU Sorenmo, E Krick, CM Coughlin, B Overley, TP Gregor, RH Vonderheide, NJ Mason
PloS one 2011
Targeting NKT cells and PD-L1 pathway results in augmented anti-tumor responses in a melanoma model
K Durgan, M Ali, P Warner, YE Latchman
Cancer Immunology, Immunotherapy 2011
HER2-based recombinant immunogen to target DCs through FcγRs for cancer immunotherapy
IG Zizzari, F Veglia, F Taurino, H Rahimi, E Quaglino, F Belleudi, F Riccardo, M Antonilli, C Napoletano, F Bellati, P Benedetti-Panici, MR Torrisi, L Frati, M Nuti, A Rughetti
Journal of Molecular Medicine 2011
TLR4 Engagement during TLR3-Induced Proinflammatory Signaling in Dendritic Cells Promotes IL-10–Mediated Suppression of Antitumor Immunity
D Bogunovic, O Manches, E Godefroy, A Yewdall, A Gallois, AM Salazar, I Marie, DE Levy, N Bhardwaj
Cancer research 2011
A multifunctional core-shell nanoparticle for dendritic cell-based cancer immunotherapy.
Cho NH, Cheong TC, Min JH, Wu JH, Lee SJ, Kim D, Yang JS, Kim S, Kim YK, Seong SY
Nature Nanotechnology 2011
Prolonged antigen storage endows merocytic DC with enhanced capacity to prime anti-tumor responses in tumor-bearing mice
RA Reboulet, CM Hennies, Z Garcia, S Nierkens, EM Janssen
Journal of immunology (Baltimore, Md. : 1950) 2010
Quality assessment of cellular therapies: the emerging role of molecular assays
DF Stroncek, P Jin, J Ren, J Feng, L Castiello, S Civini, E Wang, FM Marincola, M Sabatino
The Korean Journal of Hematology 2010
Whole tumor antigen vaccines
CL Chiang, F Benencia, G Coukos
Seminars in Immunology 2010
Dendritic cell-based immunotherapy for prostate cancer
H Jähnisch, S Füssel, A Kiessling, R Wehner, S Zastrow, M Bachmann, EP Rieber, MP Wirth, M Schmitz
Clinical & developmental immunology 2010
CCL3 and CCL20-recruited dendritic cells modified by melanoma antigen gene-1 induce anti-tumor immunity against gastric cancer ex vivo and in vivo
S He, L Wang, Y Wu, D Li, Y Zhang
Journal of Experimental & Clinical Cancer Research 2010
Cancer vaccine by fusions of dendritic and cancer cells
S Koido, E Hara, S Homma, Y Namiki, T Ohkusa, J Gong, H Tajiri
Clinical & developmental immunology 2010
1-MT enhances potency of tumor cell lysate-pulsed dendritic cells against pancreatic adenocarcinoma by downregulating the percentage of tregs
Y Li, J Xu, H Zou, C Wang
Journal of Huazhong University of Science and Technology [Medical Sciences] 2010
Viral Vaccines and CTL Response
SN Woolard, U Kumaraguru
Journal of Biomedicine and Biotechnology 2010
Novel cancer vaccine based on genes of Salmonella pathogenicity island 2
G Xiong, MI Husseiny, L Song, A Erdreich-Epstein, GM Shackleford, RC Seeger, D Jäckel, M Hensel, LS Metelitsa
International Journal of Cancer 2010
Prostate cancer as a model for tumour immunotherapy
CG Drake
Nature Reviews Immunology 2010
Gene Carriers and Transfection Systems Used in the Recombination of Dendritic Cells for Effective Cancer Immunotherapy
YZ Chen, XL Yao, Y Tabata, S Nakagawa, JQ Gao
Clinical and Developmental Immunology 2010
Overview of Cellular Immunotherapy for Patients with Glioblastoma
E Vauleon, T Avril, B Collet, J Mosser, V Quillien
Clinical and Developmental Immunology 2010
Rabies virus expressing dendritic cell-activating molecules enhances the innate and adaptive immune response to vaccination
Y Wen, H Wang, H Wu, F Yang, RA Tripp, RJ Hogan, ZF Fu
Journal of virology 2010
Three-day dendritic cells for vaccine development: antigen uptake, processing and presentation
M Bürdek, S Spranger, S Wilde, B Frankenberger, DJ Schendel, C Geiger
Journal of Translational Medicine 2010
FRET microscopy autologous tumor lysate processing in mature dendritic cell vaccine therapy
L Fiammenghi, V Ancarani, T Rosales, JR Knutson, M Petrini, AM Granato, E Pancisi, L Ridolfi, R Ridolfi, A Riccobon, P Neyroz
Journal of Translational Medicine 2010
The establishment of dendritic cell-tumor fusion vaccines for hormone refractory prostate cancer cell
TB Kim, HK Park, JH Chang, IH Choi, KH Kim, SJ Yoon, MS Lee, H Jung, CS Kim
Korean Journal of Urology 2010
Molecular signatures of maturing dendritic cells: implications for testing the quality of dendritic cell therapies
P Jin, TH Han, J Ren, S Saunders, E Wang, FM Marincola, DF Stroncek
Journal of Translational Medicine 2010
Well-defined block copolymers for gene delivery to dendritic cells: probing the effect of polycation chain-length
R Tang, RN Palumbo, L Nagarajan, E Krogstad, C Wang
Journal of Controlled Release 2010
In vivo imaging of immune cell trafficking in cancer
L Ottobrini, C Martelli, DL Trabattoni, M Clerici, G Lucignani
European Journal of Nuclear Medicine and Molecular Imaging 2010
Mitochondria-centric activation induced cell death of cytolytic T lymphocytes and its implications for cancer immunotherapy
A Chhabra
Vaccine 2010
Characterization of transglutaminase type II role in dendritic cell differentiation and function
I Matic, A Sacchi, A Rinaldi, G Melino, C Khosla, L Falasca, M Piacentini
Journal of leukocyte biology 2010
Significant anti-tumour activity of adoptively transferred T cells elicited by intratumoral dendritic cell vaccine injection through enhancing the ratio of CD8+ T cell/regulatory T cells in tumour
S Song, K Zhang, H You, J Wang, Z Wang, C Yan, F Liu
Clinical & Experimental Immunology 2010
Dendritic cells transfected with Her2 antigen-encoding RNA replicons cross-prime CD8 T cells and protect mice against tumor challenge
B Edlich, LJ Hogdal, B Rehermann, SE Behrens
Vaccine 2010
Survival in rectal cancer is predicted by T cell infiltration of tumour-associated lymphoid nodules
TP McMullen, R Lai, L Dabbagh, TM Wallace, CJ de Gara
Clinical & Experimental Immunology 2010
Dendritic Cells Loaded with Tumor B Cells Elicit Broad Immunity against Murine Gammaherpesvirus 68 but Fail To Prevent Long-Term Latency
J Weslow-Schmidt, F Ye, SS Cush, KA Stuller, MA Blackman, E Flaño
Journal of virology 2010
In vivo trafficking and immunostimulatory potential of an intranasally-administered primary dendritic cell-based vaccine
P Vilekar, V Awasthi, P Lagisetty, C King, N Shankar, S Awasthi
BMC Immunology 2010
Comparative Analysis of Cytotoxic T Lymphocyte Response Induced by Dendritic Cells Loaded with Hepatocellular Carcinoma -Derived RNA or Cell Lysate
Pan K, Zhao JJ, Wang H, Li JJ, Liang XT, Sun JC, Chen YB, Ma HQ, Liu Q, Xia JC
International journal of biological sciences 2010
Cancer vaccine development: Designing tumor cells for greater immunogenicity
Bozeman EN, Shashidharamurthy R, Paulos SA, Palaniappan R, D\u2019Souza M, Selvaraj P
2010
Tumor-infiltrating regulatory dendritic cells inhibit CD8+ T cell function via L-arginine metabolism
LA Norian, PC Rodriguez, LA O'Mara, J Zabaleta, AC Ochoa, M Cella, PM Allen
Cancer research 2009
Pulmonary surfactant: an immunological perspective
ZC Chroneos, Z Sever-Chroneos, VL Shepherd
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2009
Immunotherapy of Diffuse Gliomas: Biological Background, Current Status and Future Developments
OM Grauer, P Wesseling, GJ Adema
Brain Pathology 2009
In situ regulation of DC subsets and T cells mediates tumor regression in mice
OA Ali, D Emerich, G Dranoff, DJ Mooney
Science Translational Medicine 2009
The Tat-conjugated N-terminal region of mucin antigen 1 (MUC1) induces protective immunity against MUC1-expressing tumours
H Yang, NH Cho, SY Seong
Clinical & Experimental Immunology 2009
Protective anti-tumour immune responses by murine dendritic cells pulsed with recombinant Tat-carcinoembryonic antigen derived from Escherichia coli
MY Bae, NH Cho, SY Seong
Clinical & Experimental Immunology 2009
Immune tolerance induction by integrating innate and adaptive immune regulators
J Suzuki, C Ricordi, Z Chen
Cell transplantation 2009
Engulfing tumors with synthetic extracellular matrices for cancer immunotherapy
Y Hori, PJ Stern, RO Hynes, DJ Irvine
Biomaterials 2009
Modular injectable matrices based on alginate solution/microsphere mixtures that gel in situ and co-deliver immunomodulatory factors
Y Hori, AM Winans, DJ Irvine
Acta Biomaterialia 2009
Behavior of immune players in the tumor microenvironment
MJ Pittet
Current Opinion in Oncology 2009
Abrogation of Local Cancer Recurrence After Radiofrequency Ablation by Dendritic Cell-based Hyperthermic Tumor Vaccine
Q Liu, B Zhai, W Yang, LX Yu, W Dong, YQ He, L Chen, L Tang, Y Lin, DD Huang, HP Wu, MC Wu, HX Yan, HY Wang
Molecular Therapy 2009
Identification of a 17beta-hydroxysteroid dehydrogenase type 12 pseudogene as the source of a highly restricted BALB/c Meth A tumor rejection peptide
RC Hendrickson, VR Cicinnati, A Albers, G Dworacki, A Gambotto, O Pagliano, T Tüting, JI Mayordomo, C Visus, E Appella, J Shabanowitz, DF Hunt, AB DeLeo
Cancer Immunology, Immunotherapy 2009
Recombinant vesicular stomatitis virus transduction of dendritic cells enhances their ability to prime innate and adaptive antitumor immunity
JE Boudreau, BW Bridle, KB Stephenson, KM Jenkins, J Brunellière, JL Bramson, BD Lichty, Y Wan
Molecular Therapy 2009
Production of antibodies against multipass membrane proteins expressed in human tumor cells using dendritic cell immunization
T Tamura, J Chiba
Journal of biomedicine & biotechnology 2009
Lymphoid-tissue-specific homing of bone-marrow-derived dendritic cells
RJ Creusot, SS Yaghoubi, P Chang, J Chia, CH Contag, SS Gambhir, CG Fathman
Blood 2009
Evaluation of 3 clinical dendritic cell maturation protocols containing lipopolysaccharide and interferon-gamma
TH Han, P Jin, J Ren, S Slezak, FM Marincola, DF Stroncek
Journal of immunotherapy (Hagerstown, Md. : 1997) 2009
Generation in vivo of peptide-specific cytotoxic T cells and presence of regulatory T cells during vaccination with hTERT (class I and II) peptide-pulsed DCs
MM Aloysius, AJ Kechnie, RA Robins, C Verma, JM Eremin, F Farzaneh, NA Habib, J Bhalla, NR Hardwick, S Satthaporn, T Sreenivasan, M El-Sheemy, O Eremin
Journal of Translational Medicine 2009
In vivo dendritic cell tracking using fluorescence lifetime imaging and near-infrared-emissive polymersomes
NA Christian, F Benencia, MC Milone, G Li, PR Frail, MJ Therien, G Coukos, DA Hammer
Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging 2009
Infection-mimicking materials to program dendritic cells in situ
OA Ali, N Huebsch, L Cao, G Dranoff, DJ Mooney
Nature Materials 2009
Antigen-Specific T-Cell Response from Dendritic Cell Vaccination Using Cancer Stem-Like Cell-Associated Antigens
Q Xu, G Liu, X Yuan, M Xu, H Wang, J Ji, B Konda, KL Black, JS Yu
Stem Cells 2009
Increased extracellular pressure provides a novel adjuvant stimulus for enhancement of conventional dendritic cell maturation strategies
DH Craig, H Shiratsuchi, MD Basson
Biochemical and Biophysical Research Communications 2009
Effect of ex vivo culture duration on phenotype and cytokine production by mature dendritic cells derived from peripheral blood monocytes
A Tawab, Y Fan, EJ Read, RJ Kurlander
Transfusion 2009
Dendritic Cells as Danger-Recognizing Biosensors
M Gi, W Im, S Hong
Sensors (Basel, Switzerland) 2009
Recognition of live phosphatidylserine-labeled tumor cells by dendritic cells: a novel approach to immunotherapy of skin cancer
MR Shurin, AI Potapovich, YY Tyurina, IL Tourkova, GV Shurin, VE Kagan
Cancer research 2009
Cytosolic Delivery Mediated via Electrostatic Surface Binding of Protein, Virus, or siRNA Cargos to pH-Responsive Core−Shell Gel Particles
Y Hu, PU Atukorale, JJ Lu, JJ Moon, SH Um, EC Cho, Y Wang, J Chen, DJ Irvine
Biomacromolecules 2009
Increases in serum TARC/CCL17 levels are associated with progression-free survival in advanced melanoma patients in response to dendritic cell-based immunotherapy.
Cornforth AN, Lee GJ, Fowler AW, Carbonell DJ, Dillman RO
Journal of Clinical Immunology 2009
Tumor cell lysate-pulsed dendritic cells induce a T cell response against colon cancer in vitro and in vivo.
Wu YG, Wu GZ, Wang L, Zhang YY, Li Z, Li DC
Medical Oncology 2009
Tumor endothelial marker 8 expression levels in dendritic cell-based cancer vaccines are related to clinical outcome
Venanzi FM, Petrini M, Fiammenghi L, Bolli E, Granato AM, Ridolfi L, Gabrielli F, Barucca A, Concetti A, Ridolfi R, Riccobon A
Cancer Immunology, Immunotherapy 2009
An effective vaccine against colon cancer in mice: use of recombinant adenovirus interleukin-12 transduced dendritic cells
XZ He, L Wang, YY Zhang
World journal of gastroenterology : WJG 2008
Therapeutic dendritic cell vaccine preparation using tumor RNA transfection: a promising approach for the treatment of prostate cancer
JM Sousa-Canavez, FC Canavez, KR Leite, LH Camara-Lopes
Genetic vaccines and therapy 2008
Induction of antigen-specific cytotoxic T lymphocytes by using monocyte-derived DCs transfected with in vitro-transcribed WT1 or SART1 mRNA
M Narita, N Tochiki, A Saitoh, N Watanabe, M Kaji, N Satoh, A Yamahira, T Nakamura, M Masuko, T Furukawa, K Toba, I Fuse, Y Aizawa, M Takahashi
Medical Oncology 2008
High-Level Antigen Expression and Sustained Antigen Presentation in Dendritic Cells Nucleofected with Wild-Type Viral mRNA but Not DNA
NM Melhem, SM Gleason, XD Liu, SM Barratt-Boyes
Clinical and vaccine immunology : CVI 2008
Prevention of Both Direct and Cross-Priming of Antitumor CD8 + T-Cell Responses following Overproduction of Prostaglandin E 2 by Tumor Cells In vivo
M Ahmadi, DC Emery, DJ Morgan
Cancer research 2008
Immunologic and clinical effects of antibody blockade of cytotoxic T lymphocyte-associated antigen 4 in previously vaccinated cancer patients
FS Hodi, M Butler, DA Oble, MV Seiden, FG Haluska, A Kruse, S Macrae, M Nelson, C Canning, I Lowy, A Korman, D Lautz, S Russell, MT Jaklitsch, N Ramaiya, TC Chen, D Neuberg, JP Allison, MC Mihm, G Dranoff
Proceedings of the National Academy of Sciences 2008
Differentiation of two types of mobilized peripheral blood stem cells by microRNA and cDNA expression analysis
P Jin, E Wang, J Ren, R Childs, JW Shin, H Khuu, FM Marincola, DF Stroncek
Journal of Translational Medicine 2008
Protein disulfide isomerases are antibody targets during immune-mediated tumor destruction
C Fonseca, R Soiffer, V Ho, M Vanneman, M Jinushi, J Ritz, D Neuberg, R Stone, D DeAngelo, G Dranoff
Blood 2008
Ex vivo recovery and activation of dysfunctional, anergic, monocyte-derived dendritic cells from patients with operable breast cancer: critical role of IFN-alpha
S Satthaporn, MM Aloysius, RA Robins, C Verma, S Chuthapisith, AJ McKechnie, M El-Sheemy, W Vassanasiri, D Valerio, D Clark, JA Jibril, O Eremin
BMC Immunology 2008
Bone marrow-derived dendritic cells pulsed with tumor lysates induce anti-tumor immunity against gastric cancer ex vivo
YL Li, YG Wu, YQ Wang, Z Li, RC Wang, L Wang, YY Zhang
World journal of gastroenterology : WJG 2008
Dendritic cells pulsed with keyhole limpet hemocyanin and cryopreserved maintain anti-tumor activity in a murine melanoma model
S Teitz-Tennenbaum, Q Li, MA Davis, AE Chang
Clinical Immunology 2008
Targeting of antigens to B cells augments antigen-specific T-cell responses and breaks immune tolerance to tumor-associated antigen MUC1
C Ding, L Wang, J Marroquin, J Yan
Blood 2008
Whole tumor antigen vaccination using dendritic cells: comparison of RNA electroporation and pulsing with UV-irradiated tumor cells
F Benencia, MC Courrèges, G Coukos
Journal of Translational Medicine 2008
Increased TLR responses in dendritic cells lacking the ITAM-containing adapters DAP12 and FcRgamma
CL Chu, YL Yu, KY Shen, CA Lowell, LL Lanier, JA Hamerman
European Journal of Immunology 2008
Culture of myeloid dendritic cells from bone marrow precursors
J Boudreau, S Koshy, D Cummings, Y Wan
Journal of visualized experiments : JoVE 2008
Type 2 Bias of T Cells Expanded from the Blood of Melanoma Patients Switched to Type 1 by IL-12p70 mRNA–Transfected Dendritic Cells
K Minkis, DG Kavanagh, G Alter, D Bogunovic, D O'Neill, S Adams, A Pavlick, BD Walker, MA Brockman, RT Gandhi, N Bhardwaj
Cancer research 2008
Dual Signaling of MyD88 and TRIF are Critical for Maximal TLR4-Induced Dendritic Cell Maturation
Shen H, Tesar BM, Walker WE, Goldstein DR
Journal of immunology (Baltimore, Md. : 1950) 2008
Review of clinical studies on dendritic cell-based vaccination of patients with malignant melanoma: assessment of correlation between clinical response and vaccine parameters
Engell-Noerregaard L, Hansen TH, Andersen MH, thor Straten P, Svane IM
Cancer Immunology, Immunotherapy 2008
Series overview: Harnessing the immune system to treat cancer
Nina Bhardwaj
Journal of Clinical Investigation 2007
Dendritic cell preactivation impairs MHC class II presentation of vaccines and endogenous viral antigens
LJ Young, NS Wilson, P Schnorrer, A Mount, RJ Lundie, NL la Gruta, BS Crabb, GT Belz, WR Heath, JA Villadangos
Proceedings of the National Academy of Sciences 2007
Activation of cytotoxic T lymphocytes against CML28-bearing tumors by dendritic cells transduced with a recombinant adeno-associated virus encoding the CML28 gene
LH Xie, FW Sin, SC Cheng, YK Cheung, KT Chan, Y Xie, Y Xie
Cancer Immunology, Immunotherapy 2007

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